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17 results on '"Sellier, Pierre-Olivier"'

1. Low cabotegravir trough concentrations without oral lead-in in patients with HIV-1 switching to long-acting cabotegravir and rilpivirine

Author

Rubenstein, Emma, Diemer, Myriam, Goldwirt, Lauriane, Lascoux-Combe, Caroline, Chaix, Marie-Laure, Rami, Agathe, Ponscarme, Diane, Lafaurie, Matthieu, Denis, Blandine, De Castro, Nathalie, Gras, Julien, Liegeon, Geoffroy, Sellier, Pierre-Olivier, Deville, Laure, Chevret, Sylvie, Delaugerre, Constance, and Molina, Jean-Michel

Published
2024
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5. White blood count, D‐dimers, and ferritin levels as predictive factors of pulmonary embolism suspected upon admission in noncritically ill COVID‐19 patients: The French multicenter CLOTVID retrospective study

Author

Galland, Joris, Thoreau, Benjamin, Delrue, Maxime, Neuwirth, Marie, Stepanian, Alain, Chauvin, Anthony, Dellal, Azeddine, Nallet, Olivier, Roriz, Melanie, Devaux, Mathilde, London, Jonathan, Martin‐Lecamp, Gonzague, Froissart, Antoine, Arab, Nouara, Ferron, Bertrand, Groff, Marie‐Helene, Queyrel, Viviane, Lorut, Christine, Regard, Lucile, Berthoux, Emilie, Bayer, Guillaume, Comarmond, Chloe, Lioger, Bertrand, Mekinian, Arsène, Szwebel, Tali‐Anne, Sené, Thomas, Amador‐Boreiro, Blanca, Mangin, Olivier, Sellier, Pierre‐Olivier, Mouly, Stephane, Kevorkian, Jean‐Philippe, Siguret, Virginie, Vodovar, Dominique, Sene, Damien, Mathieu, Albertini, Sara, Bouajila, Kimbimbi, Britany, Ruxandra, Burlacu, Léa, Cacoub, Karine, Champion, Véronique, Delcey, Jean‐Guillaume, Dillinger, Florine, Feron, Aline, Frazier, Funck‐Bretano, Thomas, Diane‐Cecile, Gauthier, Jean‐François, Gautier, Patrick, Henry, Tessa, Huscenot, Izabel, Sarah, Jaulerry, Mathilde, Moenes, Jouabli, Jean‐Baptiste, Julla, Marie, Laloi Michelin, Pierre, Leroy, Amanda, Lopes, Bruno, Megarbane, Maxime, Michon, Anne‐Lise, Munier, Yoram, Nahmani, Martin, Nicol, Eroan, Nicolas, Audrey, Poulat, Eric, Revue, Pascal, Richette, Jean‐Pierre, Riveline, Emma, Rubenstein, Adrien, Zanin, Clément, Aveneau, Paul, Bastard, Diane, Beauvais, Loredana, Boghez, Alix, Borderiou, Paul, Conway, Lavignia, Cosma, Vincent, Davy, Clément, Desjardin, Sandra, Devatine, Christel, Ducroz Gerardin, Charlotte, Dupe, Chloé, Gobert, Clotilde, Gros, Soumaya, Kadiri, Enmat, Khan, Sandrine, Ongnessek, Fatima, Rhmari, Isabelle, Sacco, Natalia, Saptefrat, Pauline, Schaupp, Justine, Serre, Georgios, Sideris, Sonia, Smati, Marine, Tournier, Pauline, Treca, Tony, Truong, Mathilde, Tuffier, Mattéo, Arcelli, Yvonnick, Boue, Alban, Copie, Nicolas, Deye, Jean‐Michel, Ekherian, Zaccaria, Errabih, Antoine, Gonde, Caroline, Grant, Emmanuelle, Guerin, Adèle, Magalhaes, Isabelle, Malissin, Edouard, Meurisse, Aymen, Mrad, Giulia, Naim, Philippe, Nguyen, Kiyoko, Nitenberg, Adrien, Pepin‐Lehalleur, Arthur, Perault, Lucile, Perrin, Maxime, Renaud, Laetitia, Sutterlin, Maxime, Delrue, Virginie, Siguret, and Alain, Stepanian

Subjects
medicine.medical_specialty, pulmonary embolism, Coronavirus disease 2019 (COVID-19), Ferritin levels, D‐dimer, Gastroenterology, SARS‐CoV‐2, Fibrin Fibrinogen Degradation Products, predictive factor, Leukocyte Count, 03 medical and health sciences, Patient Admission, 0302 clinical medicine, COVID‐19, Internal medicine, D-dimer, Humans, Medicine, white blood count, Retrospective Studies, biology, SARS-CoV-2, business.industry, ferritin, COVID-19, Retrospective cohort study, Original Articles, Hematology, General Medicine, Emergency department, medicine.disease, Pulmonary embolism, Ferritin, White blood count, 030220 oncology & carcinogenesis, Ferritins, biology.protein, Original Article, France, business, 030215 immunology
Abstract

Background A high prevalence of pulmonary embolism (PE) has been described during COVID‐19. Our aim was to identify predictive factors of PE in non‐ICU hospitalized COVID‐19 patients. Methods Data and outcomes were collected upon admission during a French multicenter retrospective study, including patients hospitalized for COVID‐19, with a CT pulmonary angiography (CTPA) performed in the emergency department for suspected PE. Predictive factors significantly associated with PE were identified through a multivariate regression model. Results A total of 88 patients (median [IQR] age of 68 years [60‐78]) were analyzed. Based on CTPA, 47 (53.4%) patients were diagnosed with PE, and 41 were not. D‐dimer ≥3000 ng/mL (OR 8.2 [95% CI] 1.3‐74.2, sensitivity (Se) 0.84, specificity (Sp) 0.78, P = .03), white blood count (WBC) ≥12.0 G/L (29.5 [2.3‐1221.2], Se 0.47, Sp 0.92, P = .02), and ferritin ≥480 µg/L (17.0 [1.7‐553.3], Se 0.96, Sp 0.44, P = .03) were independently associated with the PE diagnosis. The presence of the double criterion D‐dimer ≥3000 ng/mL and WBC ≥12.0 G/L was greatly associated with PE (OR 21.4 [4.0‐397.9], P = .004). Conclusion The white blood count, the D‐dimer and ferritin levels could be used as an indication for CTPA to confirm PE on admission in non‐ICU COVID‐19 patients.

Published
2021
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7. COVID-19 convalescent plasma to treat hospitalised COVID-19 patients with or without underlying immunodeficiency

Author

Lacombe, Karine, primary, Hueso, Thomas, additional, Porcher, Raphael, additional, Mekinian, Arsène, additional, Chiarabini, Thibault, additional, Georgin-Lavialle, Sophie, additional, Ader, Florence, additional, Saison, Julien, additional, Blondel, Guillaume Martin, additional, De Castro, Nathalie, additional, Bonnet, Fabrice, additional, Cazanave, Charles, additional, François, Anne, additional, Morel, Pascal, additional, Hermine, Olivier, additional, Pourcher, Valérie, additional, Michel, Marc, additional, Lescure, Xavier, additional, Soussi, Nora, additional, Brun, Philippe, additional, Pommeret, Fanny, additional, Sellier, Pierre-Olivier, additional, Rousset, Stella, additional, Piroth, Lionel, additional, Michot, Jean-Marie, additional, Baron, Gabriel, additional, De Lamballerie, Xavier, additional, Mariette, Xavier, additional, Tharaux, Pierre-Louis, additional, Resche-Rigon, Matthieu, additional, Ravaud, Philippe, additional, Simon, Tabassome, additional, and Tiberghien, Pierre, additional

Published
2022
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8. No VTE Recurrence After 1-Year Follow-Up of Hospitalized Patients With COVID-19 and a VTE Event

Author

Delrue, Maxime, primary, Stépanian, Alain, additional, Voicu, Sebastian, additional, Nassarmadji, Kladoum, additional, Sène, Damien, additional, Bonnin, Philippe, additional, Kevorkian, Jean-Philippe, additional, Sellier, Pierre-Olivier, additional, Molina, Jean-Michel, additional, Neuwirth, Marie, additional, Vodovar, Dominique, additional, Mouly, Stéphane, additional, Mebazaa, Alexandre, additional, Mégarbane, Bruno, additional, and Siguret, Virginie, additional

Published
2022
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10. 536. Clinical Outcomes of Hospitalized COVID-19 Patients Treated with Remdesivir-NEAT ID 909REM Study

Author

Raffi, François, primary, Arber, Nadir, additional, Rokx, Casper, additional, Assoumou, Lambert, additional, Shah, Pallav L, additional, De Castro, Nathalie, additional, Bakhai, Ameet, additional, Soriano, Alex, additional, Mateu, Lourdes, additional, Lumbreras, Carlos, additional, Estrada, Vicente, additional, Curran, Adrian, additional, Sellier, Pierre-Olivier, additional, Duffy, Annie, additional, Fletcher, Carl, additional, Mozaffari, Essy, additional, Haubrich, Richard, additional, Hodgkins, Paul, additional, and Pozniak, Anton, additional

Published
2021
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11. Distribution of Cerebrospinal Fluid Biomarker Profiles in Patients Explored for Cognitive Disorders

Author

Paquet, Claire, primary, Bouaziz-Amar, Elodie, additional, Cognat, Emmanuel, additional, Volpe-Gillot, Lisette, additional, Haddad, Victor, additional, Mahieux, Florence, additional, Dekimeche, Siham, additional, Defontaines, Benedicte, additional, Chabriat, Hugues, additional, Belin, Catherine, additional, Texeira, Antonio, additional, Goutagny, Stephane, additional, Questel, Frank, additional, Azuar, Julien, additional, Sellier, Pierre-Olivier, additional, Laplanche, Jean-Louis, additional, Hugon, Jacques, additional, and Dumurgier, Julien, additional

Published
2018
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13. Faisabilité de la biopsie osseuse au lit dans un service de diabétologie pour la prise en charge des plaies de pieds suspectes d’ostéite

Author

Féron, Florine, primary, Salle-Teyssières, Laurence, additional, Laloi-Michelin, Marie, additional, Vidal-Trécan, Tiphaine, additional, Bouché, Clara, additional, Jacquier, Hervé, additional, Lecorche, Emmanuel, additional, Mougari, Faiza, additional, Lopes, Amanda, additional, Chopin, Dorothée, additional, Raskine, Laurent, additional, Sellier, Pierre-Olivier, additional, Laredo, Jean-Denis, additional, Riveline, Jean-Pierre, additional, Gautier, Jean-François, additional, and Kevorkian, Jean-Philippe, additional

Published
2017
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15. CO-84 - Faisabilité de la biopsie osseuse au lit dans un service de diabétologie pour la prise en charge des plaies de pieds suspectes d’ostéite

Author

Féron, Florine, Salle-Teyssières, Laurence, Laloi-Michelin, Marie, Vidal-Trécan, Tiphaine, Bouché, Clara, Jacquier, Hervé, Lecorche, Emmanuel, Mougari, Faiza, Lopes, Amanda, Chopin, Dorothée, Raskine, Laurent, Sellier, Pierre-Olivier, Laredo, Jean-Denis, Riveline, Jean-Pierre, Gautier, Jean-François, and Kevorkian, Jean-Philippe

Published
2017
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17. Brief Report: Efficacy and Safety of Efavirenz, Raltegravir, and Dolutegravir in HIV-1/TB Coinfection. A Multicenter Retrospective Cohort Study in France.

Author

Kherabi Y, de Castro N, Sellier PO, Hamet G, Brun A, Méchaï F, Joly V, Yazdanpanah Y, and Molina JM

Subjects
Alkynes, Benzoxazines adverse effects, Cyclopropanes, Heterocyclic Compounds, 3-Ring, Humans, Oxazines therapeutic use, Piperazines, Pyridones, Raltegravir Potassium adverse effects, Retrospective Studies, Treatment Outcome, Viral Load, Anti-HIV Agents adverse effects, Coinfection drug therapy, HIV Infections complications, HIV Infections drug therapy, HIV-1 genetics, Tuberculosis complications, Tuberculosis drug therapy
Abstract

Background: There are limited data comparing the efficacy and safety of raltegravir and dolutegravir to that of efavirenz in HIV-1/tuberculosis (TB) coinfected patients., Methods: We conducted a 10-year retrospective study in 4 centers in France. We included all HIV-1/tuberculosis coinfected patients starting antiretroviral therapy with a rifampicin-based regimen, with a plasma HIV RNA level (VL) > 1000 copies/mL. The primary endpoint was the proportion of patients with virological success that is, with VL <50 copies/mL at W48 using an Intention-To-Treat analysis, using last-observation-carried-forward to impute missing data. We also assessed antiretroviral therapy safety, analyzing treatment discontinuation for adverse events., Results: Between 2010 and 2020, 117 patients were included. Thirty-nine (33.3%) were treated with raltegravir and 2 nucleoside reverse transcriptase inhibitors (NRTIs), 19 (16.2%) with dolutegravir (and 2 NRTIs) and 59 (50.4%) with efavirenz (and 2 NRTIs). At W48, the primary endpoint was achieved in 24 patients (61.5%) in the raltegravir group, in 12 (63.2%) in the dolutegravir group, and in 41 (69.5%) in the efavirenz group using an Intention-To-Treat analysis ( P = 0.68). Emergence of drug resistance in patients with virological failure, defined as a VL >50 copies/mL, was observed in 3 patients with efavirenz and one patient with raltegravir. Rate of treatment discontinuation for drug-related adverse events was 10.3%, 10.6%, 16.9% for raltegravir, dolutegravir and efavirenz respectively ( P = 0.67)., Conclusions: In this retrospective cohort study, raltegravir and dolutegravir yielded similar efficacy and safety results to efavirenz for the treatment of HIV-1/TB coinfected patients., Competing Interests: The authors have no conflicts of interest to disclose., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)

Published
2022
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