1. Does the Daily Dose of Tadalafil for the Treatment of Erectile Dysfunction Increase Penile Sensation?
- Author
-
Selim Taş, Ekrem İslamoğlu, Ali Eren, and Murat Savaş
- Subjects
erectile dysfunction ,oral phosphodiesterase-5 inhibitors ,penile sensation ,Surgery ,RD1-811 ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Objective:To investigate the effect of tadalafil, used for treating erectile dysfunction (ED) at a daily dose of 5 mg for 12 weeks, on penile sensation.Materials and Methods:Our study included 30 male patients who applied to our andrology outpatient clinic with the complaint of ED and were prescribed tadalafil at a daily dose of 5 mg for 12 weeks. Before treatment, serum levels of testosterone and luteinizing hormone (LH) were measured. Demographic and clinical characteristics were recorded. Pre- and post-treatment electromyography (EMG) examinations for penile sensation and International Index of Erectile Function (IIEF-5) scoring were performed for each patient.Results:The mean age was 53±9 years. The mean body mass index was 27±2. Before treatment, serum levels of testosterone and LH were within the normal range. There were 8 (29%) patients with diabetes mellitus and 7 (25%) patients with hypertension. The pre- and post-treatment IIEF-5 scores were 13±3 and 19±3, respectively. Nerve conduction velocities (NCV) increased from 35.5 m/sec to 38.05 m/sec. Latency values decreased from 2.32 ms to 2.14 ms. There was a statistically significant improvement in IIEF-5 scores and EMG results for penile sensation after treatment (IIEF-5, NCV and latency; p
- Published
- 2023
- Full Text
- View/download PDF