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Aim: We aimed to investigate the effects of anxiety or social support on sleep quality in patients with COVID-19 who were older than 65 years of age and undergoing quarantine process. Material and Method: The study included the patients ≥65 years of age who had a quarantine process for 14 days during the COVID-19 outbreak. The sociodemographic features and comorbidities were recorded in all patients. Geriatric Anxiety Scale (GAS), Multidimensional Perceived Social Support Scale (SS), and Pittsburgh Sleep Quality Index (PSQI) questionnaires were applied. Results: Totally 198 patients (123 male and 75 female) were included in the study. Among patients, 115 (58.1%) patients were living in a nursing home. All GAS scores and the total PSQI were significantly higher and all SS scores were significantly lower in PCR positive patients compared with the negative ones (p:0.001). Moreover, All GAS scores and the total PSQI were significantly higher and all SS scores were significantly lower in patients living in nursing homes compared with the others (p:0.001). Conclusion: In elderly patients faced with the COVID-19, social support was negatively associated with the sleep disturbances. We suggest that, increasing social support is important in elderly patients in the clash against COVID-19.

Amaç: Obstruktif uyku apne (OUA) olgularının bağışıklık sisteminin olumsuz etkilendiği ve COVİD enfeksiyonunun ağır seyredebileceğine yönelik öngörüler mevcuttur. Bu çalışmada Tekirdağ Devlet Hastanesi’nde COVID-19 tanısı almış olguların uyku kalitesi ve OUAS semptomlarının ve COVİD klinik derecesi ile ilişkisinin araştırılması amaçlanmıştır. Materyal ve Metot: Çalışmamız Coronavirus hastalığı 2019 (COVID-19) salgının ülkemizde ilk yükselişi sırasında 15 Mart 2020- 30 Mayıs 2020 tarihleri arasında Tekirdağ Devlet Hastanesine başvurmuş ve sereolojik testleri pozitif ve klinik olarak tanı konmuş bireylerde yapılmıştır. Tüm olgular Epworth Uykululuk skalası ve Berlin Uyku anketine göre OUA düşünülen olgularda klinik şiddet arasında ilişki ve uyku kalitesi değerlendirildi. Bulgular: COVİD-19 olgularında semptomatik olması ve obezite varlığı ile Epworth gündüz uykululuğu arasında istatistiksel olarak anlamlı bir ilişki olduğu tespit edildi (p

Aim: The main focus of this study is to determine blood malondialdehyde (MDA), Glutathione (GSH) and nitric oxide (NO) levels in patients with possible Alzheimer’s disease (AD).Material and Method: The study included 15 healthy persons and 15 Alzheimer’s patients aged between 65 and 79 living in Kars. Before taking blood samples from patients who were diagnosed with Alzheimer at Kafkas University Faculty of Medicine Neurology Service, they were applied Standardized Mini Mental State Examination (SMMSE) and Clinical Dementia Rating. In the next step, erythrocyte GSH and serum MDA, NO levels were determined.Results: The difference between healthy persons and Alzheimer’s disease group erythrocyte GSH (p

Objective: To evaluate the effects of temporal lobe epilepsy (TLE) on corpus callosum (CC) morphometry in patients with TLE. Methods: This retrospective study was conducted at the Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey between November 2010 and December 2013. The epileptic syndrome diagnosis was based on International League Against Epilepsy criteria, and this study was conducted on the MRIs of 25 epilepsy patients and 25 control subjects. We classified the patients according to their duration of epilepsy: < 10 and >= 10 years. The projection area length (PAL) of the CC was also estimated. Total brain volumes (TBV) were measured on CT images. Results: The mean values of TBV for patients with TLE and the control group were not statistically different, but the CC PAL values were statistically different. The mean CC PAL values of under and over 25 years of age in patients with TLE were statistically different. The mean values of TBV of under and over 10 years duration of TLE were small statistically, but the CC PAL values were statistically different. Conclusion: The results indicate a clear influence of TLE on the structure of the CC rather than TBV.

A 72-year-old female was admitted to our outpatient clinic with the complaints of slowed movements and sudden speeding up of her walk. She was identified to have cavernous angioma with left basal ganglion localization. The patient did not demonstrate a levodopa response and refused to have surgical treatment. The cause underlying this clinical presentation was identified as the chronic pressure brought forward by the cavernous hemangioma. We present this patient as a case report, because cavernous angioma with basal ganglia localization is an unusual cause of secondary parkinsonism.

The available data on the activity of paraoxonase-1 (PON1) in patients suffering from migraine without aura (MWoA) is scarce. The present study was conducted to fulfill the objective of investigating the probability of an association between PON1 phenotype distribution and headache duration in patients suffering from MWoA. Materials and methods: Seventy-six patients who suffer from MWoA and were not experiencing attacks at the time and 65 healthy volunteers were enrolled for the purpose of evaluation in the present study. Results: The levels of serum paraoxonase, arylesterase activities, and lipid hydroperoxide (LOOH) were determined for these subjects. The results obtained revealed that no statistical differences existed between the group suffering from MWoA and the control group with respect to the PON1 activity and the phenotype distribution (all values of P > 0.05), while the levels of serum LOOH were noted to be higher (P < 0.05) in the patient group. However, a significant relation was found between the PON1192QR phenotype distribution and headache duration in patients suffering from MWoA (P < 0.001). It was observed that patients with the PON1192QR (BB = homozygous high activity) polymorphism had headaches of shorter duration than patients with the PON1192QQ (AA = homozygous low activity) and PON1192QR (AB = heterozygous intermediate activity) polymorphisms. Along with these results, significant negative correlations were found between the ratio of salt-stimulated paraoxonase/arylesterase and headache duration (r: -0.40, P < 0.001) in patients suffering from MWoA in comparison to the control group. Finally, the activities of both paraoxonase and arylesterase were found to be inversely correlated with the levels of serum LOOH in the patient group [(r: -0.23, P < 0.05) and (r: -0.27, P < 0.05), respectively]. Conclusion: The results ascertained through the present study suggest that a significant correlation exists between PON1 phenotype distribution and headache duration in patients suffering from MWoA. Additionally, to the best of our knowledge, this is the first study to evaluate the association between PON1 polymorphism and headache duration in patients with migraine. PON1 phenotype distribution will play a key role in headache duration in patients with migraine.

We aimed to determine the prevalence of primary headache among schoolchildren in the city of Agri, located in eastern Turkey, where geographical, climatic and socio-economic conditions differ greatly from those of other regions of Turkey. A cross-sectional school-based (ages ranging from 11 to 18) study was conducted from January to April 2006. Diagnosis was based on the second edition of the International Classification of Headache Disorders. This population was evaluated by a two-stage clustered sampling procedure. In the first phase, 1385 children were asked whether they had had a headache within the past year. For the second-step interview, 540 children (38.9%) with a complaint of headache were selected. Five children who had complained of headaches in the first interview did not agree to participate in the second stage. Of the remaining 535, 473 were identified as having primary headache and 62 as having secondary headache. Overall, one-year prevalence of headache subtypes was 14.3% for migraine, 3.5% for probable migraine, 8.6% for pure tension-type headache, 4.6% for migraine plus tension-type headache, and 3.0% for probable migraine plus tension-type headache. The prevalence of migraine was higher in our study than in previous studies.