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2. A Comparative Study between cefpirome (CPR) and ceftazidime (CAZ) in Respiratory Tract Infections

Author

SOEJIMA, Rinzo, primary, SUMI, Masaru, additional, HINO, Jiro, additional, OKIMOTO, Niro, additional, KAWAKAMI, Yoshikazu, additional, YAMAGUCHI, Etsuro, additional, TERAI, Tsugio, additional, YOSHIKAWA, Takashi, additional, TAKAOKA, Kazuo, additional, SAITO, Akira, additional, TOMIZAWA, Masumi, additional, NAKAYAMA, Ichiro, additional, SHIBAKI, Hidetoshi, additional, TANEICHI, Koji, additional, KIKUIRI, Tsuyoshi, additional, SHINOHARA, Masahide, additional, MIWA, Akira, additional, ITO, Choei, additional, SATO, Mitsuo, additional, SUZUKI, Akira, additional, HONDA, Yasuhito, additional, SEKINE, Kyuichiro, additional, HIRAGA, Yomei, additional, OMICHI, Mitsuhide, additional, YASUDA, Shinya, additional, KOROKU, Tetsuji, additional, ITO, Susumu, additional, KASAGI, Shoji, additional, ONODERA, Sokichi, additional, OSAKI, Yoshinobu, additional, MATSUMOTO, Hiroyuki, additional, OTA, Takafumi, additional, SAKAI, Eiichi, additional, SHIMIZU, Tetsuo, additional, SASAKI, Nobuhiro, additional, FUJIKANE, Toshiaki, additional, FUJIUCHI, Satoshi, additional, SHISHIDO, Toshiaki, additional, TAKEBE, Kazuo, additional, YANADA, Atsuko, additional, MASUDA, Mitsuo, additional, MURAKAMI, Seiichi, additional, IMAMURA, Kenichi, additional, TAMURA, Toyokazu, additional, ENDO, Katsumi, additional, MURABAYASHI, Hideya, additional, OCHIAI, Shigeru, additional, SAWADA, Hidekazu, additional, SHIMURA, Michitaka, additional, TAMURA, Masashi, additional, KONISHI, Kazuki, additional, YOSHIDA, Taiji, additional, SUDO, Morio, additional, BANDO, Takeshi, additional, SATO, Nobuhisa, additional, OURA, Masayuki, additional, UNOURA, Tetsuro, additional, MOURI, Takashi, additional, TAKISHIMA, Tamotsu, additional, TANNO, Yasuo, additional, KUDO, Kunio, additional, ISHII, Munehiko, additional, SUGIYAMA, Masaharu, additional, MOTOMIYA, Masakichi, additional, WATANABE, Akira, additional, NAGAI, Kosaku, additional, SATO, Kazuo, additional, KONNO, Kiyoshi, additional, HASUIKE, Teruo, additional, SHIDA, Kuniharu, additional, SHINDO, Satoshi, additional, HAYASHI, Izumi, additional, SHIMADA, Jingoro, additional, YOSHIDA, Masaki, additional, SAITO, Atsushi, additional, SHIBA, Koya, additional, KAJI, Masanobu, additional, HORI, Seiji, additional, SAKAI, Osamu, additional, MIYASHITA, Hideo, additional, ONO, Yasuo, additional, BABA, Masumi, additional, KOBAYASHI, Hiroyuki, additional, OSHITANI, Hiroshi, additional, MIURA, Hiroshi, additional, INOUE, Takashi, additional, SHIMADA, Kaoru, additional, GOTO, Mieko, additional, GOTO, Hajime, additional, SANO, Yasuyuki, additional, MIYAMOTO, Yasufumi, additional, ARAI, Yasuo, additional, MATSUMURA, Kanzaburo, additional, NAKAMORI, Yoshitaka, additional, NARUI, Koji, additional, NOGUCHI, Masayuki, additional, NAKATANI, Tatsuo, additional, NAKATA, Koichiro, additional, SAKURAI, Iwao, additional, IMAI, Takeo, additional, MATSUMOTO, Fumio, additional, ODAGIRI, Shigeki, additional, MATSUMURA, Masanori, additional, SUZUKI, Kaneo, additional, MUROHASHI, Kou, additional, TAKAHASHI, Hiroshi, additional, TAKAHASHI, Kenichi, additional, YOSHIOKA, Teruaki, additional, KOYAMA, Izumi, additional, OGURA, Takashi, additional, ARAKAWA, Masaaki, additional, WADA, Koichi, additional, KAWASHIMA, Takashi, additional, TAKATO, Masanaga, additional, KUMANO, Hidenori, additional, AOKI, Nobuki, additional, SATAKE, Tatsuo, additional, YAMAKI, Kenichi, additional, SUZUKI, Ryujiro, additional, TAKAGI, Kenzo, additional, TANAKA, Hitoshi, additional, IMAI, Masatoshi, additional, TSUNODA, Toshiaki, additional, WATANABE, Yoshiaki, additional, TAKEUCHI, Toshihiko, additional, HAYASHI, Yoshimitsu, additional, YAMAMOTO, Kazuhide, additional, YAMADA, Yasuo, additional, KUZE, Fumiyuki, additional, MURAYAMA, Takako, additional, SUZUKI, Katsuhiro, additional, KATO, Motokazu, additional, CHIBA, Masaru, additional, YAMAGUCHI, Riyo, additional, NAGAI, Hitoshi, additional, UMEDA, Fumikazu, additional, TOMIOKA, Hiromi, additional, EBISUI, Osamu, additional, IWASAKI, Hironobu, additional, BANDO, Kenji, additional, NISHIMURA, Takashi, additional, OYAIZU, Tatsuki, additional, ISHIDA, Sunao, additional, OHSHIMA, Shunsaku, additional, KADO, Masao, additional, YASUBA, Hirotaka, additional, SUGIMOTO, Kikuo, additional, YONEZU, Seibun, additional, UEDA, Yoshihiro, additional, YASUNAGA, Kojiro, additional, MIKI, Fumio, additional, TSUBURA, Eiro, additional, NAKAGAWA, Masaru, additional, OGURA, Takeshi, additional, OGUSHI, Fumitaka, additional, KAWANISHI, Masashi, additional, ICHIKAWA, Waka, additional, MIZUNO, Kazuhito, additional, ISHIKAWA, Seiko, additional, TAKISHITA, Yoshihiro, additional, BANDO, Hiroyasu, additional, HASHIMOTO, Yoshihiro, additional, NARITA, Nobuhiro, additional, SAWAKI, Masayoshi, additional, MIKASA, Keiichi, additional, KONISHI, Mitsuru, additional, MATSUSHIMA, Toshiharu, additional, KIMURA, Makoto, additional, KAWANISHI, Masayasu, additional, KURIMURA, Tadasu, additional, SASAKI, Hideo, additional, FUKUHARA, Hirofumi, additional, SASAKI, Takao, additional, MATSUMOTO, Yukio, additional, SUGIMOTO, Yuji, additional, SAWAE, Yoshiro, additional, ISHIMARU, Toshiyuki, additional, TAKAGI, Koji, additional, SHIMONO, Nobuyuki, additional, SHIGEMATSU, Nobuaki, additional, YAGAWA, Katsuro, additional, HAYASHI, Shinichiro, additional, KONO, Kenji, additional, ONUKI, Keisuke, additional, TOHARA, Shinichi, additional, TAKEDA, Seiji, additional, TAKII, Masahide, additional, OKUDAIRA, Katsumi, additional, SAKAUE, Akihiko, additional, SHINOHARA, Koichi, additional, OIZUMI, Kotaro, additional, ICHIKAWA, Yoichiro, additional, KAWAHARA, Masashi, additional, HARA, Kohei, additional, HIROTA, Masaki, additional, YAMAGUCHI, Keizo, additional, KONO, Shigeru, additional, KOGA, Hironobu, additional, KAKU, Mitsuo, additional, DOTSU, Yasumasa, additional, YAMADA, Hiroshi, additional, FUKUSHIMA, Kiyoyasu, additional, SUYAMA, Naofumi, additional, HAYASHI, Toshiaki, additional, MATSUMOTO, Keizo, additional, YOSHIDA, Toshiaki, additional, NAGATAKE, Tsuyoshi, additional, AKIYAMA, Moritoshi, additional, TAKASUGI, Masakazu, additional, TAGUCHI, Mikio, additional, WATANABE, Kiwao, additional, SHISHIDO, Harumi, additional, SHIMA, Kiyoshi, additional, TAKENAKA, Shinobu, additional, NASU, Masaru, additional, GOTO, Jun, additional, SHIGENO, Hideaki, additional, GOTO, Yoichiro, additional, TASHIRO, Takayoshi, additional, NAGAI, Hiroyuki, additional, YAMAZAKI, Toru, additional, AKASHI, Mitsunobu, additional, FUKUHARA, Hiroshi, additional, KANESHIMA, Hiroshi, additional, IRABU, Yuei, additional, SHIMOJI, Katsuyoshi, additional, KITSUKAWA, Keizo, additional, SHIGENO, Yoshiteru, additional, and OGAWA, Nobuya, additional

Published
1991
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4. Comparative Study of the Effectiveness of Mezlocillin and Ampicillin on Respiratory Tract Infection

Author

KITAMOTO, Osamu, primary, KOBAYASHI, Hiroyuki, additional, TAKAMURA, Mitsuko, additional, NAGAHAMA, Fumio, additional, YASUDA, Shinya, additional, NAKABAYASHI, Takehito, additional, HIRAGA, Yomei, additional, TAKAGI, Hiroshi, additional, YAGUCHI, Kei, additional, OGI, Mitsuharu, additional, KUZE, Akihiko, additional, KUREMATSU, Saburo, additional, HARADA, Kazunori, additional, MATSUI, Katsuhiko, additional, SAITO, Akira, additional, ISHIKAWA, Kiyofumi, additional, TOMIZAWA, Masumi, additional, ABE, Morikuni, additional, UJIIE, Akira, additional, NAKAYAMA, Ichiro, additional, TAKASHIRO, Yoshinobu, additional, TANGO, Mikihiko, additional, KINOSHITA, Yoshio, additional, SHIBAKI, Hidetoshi, additional, KONNO, Takahiko, additional, TAKEBE, Kazuo, additional, IMAMURA, Kenichi, additional, KUMASAKA, Yoshihiro, additional, NAKAHATA, Hisashi, additional, YOSHIDA, Shuichiro, additional, OKAMOTO, Katsuhiro, additional, KAWABE, Hiroyasu, additional, MURAKAMI, Seiichi, additional, MIYAZAWA, Tadashi, additional, ENDO, Katsumi, additional, KITAOKA, Masafumi, additional, KOMORI, Tetsuo, additional, WATANABE, Hajime, additional, OSONOI, Ken, additional, BABA, Tsuneharu, additional, TAMURA, Toyokazu, additional, KOMORI, Kozue, additional, MASAKI, Naoyoshi, additional, MASUDA, Mitsuo, additional, TAKISHIMA, Tamotsu, additional, ARAI, Sumio, additional, KONISHI, Kazuki, additional, KONNO, Kiyoshi, additional, OIZUMI, Kotaro, additional, HAYASHI, Izumi, additional, KOBAYASHI, Setsuo, additional, FUEKI, Ryuzo, additional, NEMOTO, Toshikazu, additional, NAKAZAWA, Tsugio, additional, TOMIOKA, Shinichi, additional, KONDO, Tadanori, additional, AOKI, Hideo, additional, ABE, Osamu, additional, KOBAYASHI, Toshio, additional, OHZEKI, Hideo, additional, SAKURAI, Yasuyoshi, additional, KONDO, Kazuo, additional, NAGASAWA, Tohru, additional, MOTOHASHI, Yutaka, additional, MATSUMOTO, Shigeru, additional, YAMADA, Mamoru, additional, AKIYAMA, Takashi, additional, TANAKA, Tetsuharu, additional, SAITO, Tatsuo, additional, HAGIWARA, Osamu, additional, DOBASHI, Kunio, additional, Yokoyama, Akira, additional, KATSU, Masataka, additional, OKUI, Shinji, additional, KAWAI, Mieko, additional, AOYAGI, Akio, additional, KOIZUMI, Yuichi, additional, IKEMOTO, Hideo, additional, WATANABE, Kazuyoshi, additional, SAITO, Atsushi, additional, SHIMADA, Jingoro, additional, OHMORI, Masahisa, additional, SHIBA, Kohya, additional, YAMAJI, Takehisa, additional, IHARA, Hironobu, additional, HOJO, Toshio, additional, MIYAHARA, Tadashi, additional, MASHIMO, Keimei, additional, YAMAOKA, Sumio, additional, NAKAGAWA, Keiichi, additional, WATANABE, Kentaro, additional, KOYAMA, Masaru, additional, FUKUI, Hiroshi, additional, UEDA, Masami, additional, KABE, Junzaburo, additional, TANIMOTO, Hiroichi, additional, NAKADA, Koichiro, additional, TACHIBANA, Akio, additional, SUZUKI, Kanzo, additional, TANAKA, Motoichi, additional, SEKINE, Kyuichiro, additional, NAKAGAWA, Takashi, additional, FUKUSHIMA, Kokichi, additional, ITO, Akira, additional, SHINDO, Kunihiko, additional, ODAGIRI, Shigeki, additional, HASEGAWA, Hideyuki, additional, KURIHARA, Makio, additional, TAKIGAMI, Tadashi, additional, FUJIMORI, Ippei, additional, KOBAYASHI, Yoshio, additional, OBANA, Mitsuo, additional, YAMASAKU, Fusanosuke, additional, SEKINE, Osamu, additional, USUDA, Yoshimaru, additional, AOKI, Nobuki, additional, OYAMA, Kaoru, additional, SUZUKI, Kuninori, additional, YAMAMOTO, Toshiyuki, additional, MORI, Kohzo, additional, MAEKAWA, Nobuo, additional, NAKANISHI, Michiyasu, additional, AMITANI, Ryoichi, additional, MOCHIZUKI, Yoshiro, additional, KADO, Shigechika, additional, HASE, Mitsuo, additional, INABA, Norio, additional, ODA, Yoshiro, additional, UCHIHIRA, Fumiaki, additional, SHIOTA, Kenzo, additional, MIKI, Fumio, additional, TAKAMATSU, Kenji, additional, OKUBO, Hiroshi, additional, OKAMOTO, Yuruko, additional, MAEHARA, Keigo, additional, SHIMOMURA, Atsushi, additional, SOEJIMA, Rinzo, additional, NIKI, Yoshito, additional, KISHIMOTO, Sumio, additional, ARAKAWA, Masami, additional, NISHIMOTO, Yukio, additional, YAMAKIDO, Michio, additional, WATANABE, Takashi, additional, KODOMARI, Naomi, additional, IWAMOTO, Keiko, additional, SAKAI, Kiyoko, additional, AKAGAWA, Takaaki, additional, KURIMURA, Osamu, additional, SADAMOTO, Kazue, additional, SASAKI, Hideo, additional, TSUBURA, Eiro, additional, TAKISHITA, Yoshihiro, additional, GOTO, Toshihiro, additional, MORIOKA, Shigeharu, additional, DOI, Hiroyuki, additional, SAWAE, Yoshiro, additional, OKADA, Kaoru, additional, KARIBE, Chie, additional, TAKIHARA, Yoshihiro, additional, NAGANO, Hiroshi, additional, MATSUMOTO, Norichika, additional, TANAKA, Yasunori, additional, KAJI, Masaro, additional, ICHIKAWA, Yoichiro, additional, HAYASHI, Shunji, additional, TANAKA, Fumiro, additional, YANO, Takafumi, additional, OKAWA, Yayoi, additional, MATSUMOTO, Takuro, additional, KANEKO, Kazutoyo, additional, NAKAMURA, Eiji, additional, TACHIBANA, Masayuki, additional, NAKAZONO, Hidero, additional, OHNUKI, Tatsuya, additional, MINAMI, Hiroshi, additional, SAEKI, Kenji, additional, KINOSHITA, Akira, additional, MIYAHARA, Yoichi, additional, YASUDA, Kaori, additional, NISHIDA, Masakatsu, additional, HARA, Kohei, additional, NAKATOMI, Masao, additional, SUYAMA, Naofumi, additional, NAGASAWA, Masao, additional, ICHIMARU, Haruaki, additional, KOMORI, Munetaka, additional, MATSUMOTO, Keizo, additional, and SUZUKI, Hiroshi, additional

Published
1981
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5. Comparison of HAPA-B and Amikacin in the Treatment of Respiratory Tract Infections

Author

KOBAYASHI, Hiroyuki, primary, OSHITANI, Hiroshi, additional, YOSHIDA, Masahiko, additional, SAITO, Akira, additional, NAKAYAMA, Ichiro, additional, ONODERA, Sokichi, additional, SASAKI, Nobuhiro, additional, NAGAHAMA, Fumio, additional, HIRAGA, Yomei, additional, NAKABAYASHI, Takehito, additional, SEKINE, Kyuichiro, additional, SHIMOMURA, Jutaro, additional, TAKEBE, Kazuo, additional, KOSAKA, Shiro, additional, MASUDA, Mitsuo, additional, MURAKAMI, Seiichi, additional, KIMURA, Kenichi, additional, KASHIWAMURA, Hideaki, additional, GASA, Keiko, additional, TAMURA, Masao, additional, KONISHI, Kazuki, additional, ITO, Takashi, additional, NEMOTO, Yoshikatsu, additional, KURAMITSU, Hiroshi, additional, GOMI, Kazutoshi, additional, HAYASHI, Izumi, additional, KATSU, Masataka, additional, YAMAGATA, Hajime, additional, SATOH, Minoru, additional, UEDA, Yasushi, additional, SAITO, Atsushi, additional, MIYAHARA, Tadashi, additional, KABE, Junzaburo, additional, KUDOH, Koichiro, additional, SANO, Yasuyuki, additional, HAIDA, Michiko, additional, TAKAHASHI, Terumi, additional, KASAHARA, Keita, additional, FUJIMORI, Ippei, additional, KOBAYASHI, Yoshio, additional, MITA, Seiji, additional, MITSUI, Takeshi, additional, OKUBO, Takao, additional, ITO, Akira, additional, ODAGIRI, Shigeki, additional, SUZUKI, Kaneo, additional, MUROHASHI, Koou, additional, SEKINE, Osamu, additional, USUDA, Yoshimaru, additional, AOKI, Nobuki, additional, OYAMA, Kaoru, additional, YAMASHITA, Naohiro, additional, YANO, Saburo, additional, SHIMOKATA, Kaoru, additional, SENDA, Yoshihiro, additional, TORII, Yoshio, additional, YOSHII, Saizi, additional, NISHIWAKI, Keisuke, additional, KOHNOU, Osamu, additional, KATO, Masahito, additional, KATO, Joichi, additional, HANAKI, Hidekazu, additional, TAKEUCHI, Toshihiko, additional, SUGIMOTO, Kikuo, additional, SHIMADA, Kazue, additional, FUKUNAGA, Takafumi, additional, SATAKE, Kisao, additional, OHTA, Hikaru, additional, NISHIMURA, Toshio, additional, NAKASHIMA, Michiro, additional, IKEDA, Sadao, additional, NANBA, Hidehiro, additional, MIKI, Fumio, additional, IKUNO, Yoshiyasu, additional, INOUE, Eiji, additional, YOSHIYAMA, Minoru, additional, HIRAGA, Tooru, additional, MURATA, Akihito, additional, NAKAJIMA, Shigenori, additional, TSUYA, Yasuo, additional, UENISHI, Hiroki, additional, SOEJIMA, Rinzo, additional, KAWANE, Hiroshi, additional, NIKI, Yoshihito, additional, YAGI, Susumu, additional, SUMI, Masaru, additional, YAMAKIDO, Michiro, additional, KAMITSUNA, Akimitsu, additional, ITASAKA, Masakazu, additional, HASEGAWA, Kenji, additional, SAWAE, Yoshiro, additional, OKADA, Kaoru, additional, KUMAGAI, Yukio, additional, HAYASHI, Shinichiro, additional, SHIGEMATSU, Nobuaki, additional, NAGANO, Hitoshi, additional, KUBO, Chiharu, additional, KARIYA, Masahito, additional, NASU, Masaru, additional, GOTO, Jun, additional, GOTO, Yoichiro, additional, HARA, Kohei, additional, YAMAGUCHI, Keizo, additional, SHIGENO, Yoshiteru, additional, KOHNO, Shigeru, additional, OE, Toshiyuki, additional, FUJITA, Kiyo, additional, UEDA, Yasuko, additional, KOHNO, Kota, additional, MATSUMOTO, Keizo, additional, YOSHIDA, Toshiaki, additional, OISHI, Kazunori, additional, ARAKI, Shukuro, additional, ANDO, Masayuki, additional, SUGA, Moritaka, additional, SHIMA, Kiyoshi, additional, FUKUDA, Yasutsugu, additional, TOKUNAGA, Katsumasa, additional, TAKENAKA, Shinobu, additional, HIGUCHI, Sadanobu, additional, FUJISE, Ryuji, additional, TAMIYA, Jiro, additional, MOTOZATO, Yuichi, additional, ITO, Kiyotaka, additional, ITSUNO, Kiyonori, additional, SAKURAMI, Takehiko, additional, and FUJISAKI, Kunio, additional

Published
1986
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7. [Comparative Study of the Antiemetic Palonosetron for Lung Cancer Patients Treated with a Divided Dose of Cisplatin].

Author

Umehara K, Wakamoto A, Hatsuyama T, Sato H, Kobayashi M, Fujita A, and Sekine K

Subjects
Cisplatin therapeutic use, Female, Humans, Male, Middle Aged, Nausea chemically induced, Palonosetron, Retrospective Studies, Treatment Outcome, Vomiting chemically induced, Antiemetics therapeutic use, Cisplatin adverse effects, Isoquinolines therapeutic use, Lung Neoplasms drug therapy, Nausea prevention & control, Quinuclidines therapeutic use, Vomiting prevention & control
Abstract

Palonosetron(Palo)is a second-generation 5-hydroxytryptamine 3 receptor antagonist(5-HT3RA)effective in suppressing chemotherapy-induced nausea and vomiting in both acute and delayed phases.Most studies have reported Palo as an effective antiemetic for cisplatin(CDDP)chemotherapy(≥50mg/m2)administered on an intermittent basis.To assess the antiemetic efficacy of Palo, we performed a retrospective study in 16 patients with lung cancer who received Palo with split-dose CDDP, ifosfamide, and irinotecan(CPT-11)triple combination(CIC)therapy at Sapporo Minami-Sanjo Hospital between October 2010 and January 2012.T he CIC regimen consisted of CPT-11(50-60mg/m2)administered on days 1, 8, and 15, in addition to CDDP(15-20mg/m2)and ifosfamide(1,500mg/kg)for 4 consecutive days.On day 1, ramosetron was replaced with Palo in patients who had insufficient antiemetic control in accordance with guidelines on the management of highly emetogenic chemotherapy(HEC).There was a lower incidence of grade 1 or higher nausea(62.5%)in patients in the Palo-combination group than in those in the non-Palo-combination group(87.5%).No incidence of grade 3 or higher nausea was reported in either group.On the fifth day of chemotherapy, the incidence of nausea was significantly lower in the Palo-combination group(43.8%)than in the non-Palo-combination group(81.3%)(p<0.05).In addition, there was a significant decrease in the number of days of incidence and a significant increase in the number of days since the last episode was observed in the Palo-combination group.These results suggest that Palo, in particular, decreases the incidence of nausea and extends the number of days since its occurrence; moreover, it is effective in accelerating recovery.In conclusion, this study suggests that Palo exhibits excellent antiemetic efficacy in patients administered split doses of CDDP.

Published
2016

8. [Comparative study of an antiemetic NK1 receptor-antagonist in lung cancer patients treated with divided doses for Cisplatin].

Author

Sato H, Wada K, Umehara K, Otsu K, Wakamoto A, Hatsuyama T, Fujita A, and Sekine K

Subjects
Cisplatin administration & dosage, Humans, Male, Middle Aged, Nausea chemically induced, Vomiting chemically induced, Antiemetics therapeutic use, Cisplatin adverse effects, Lung Neoplasms drug therapy, Nausea prevention & control, Neurokinin-1 Receptor Antagonists, Vomiting prevention & control
Abstract

Aprepitant is a NK1 receptor-antagonist with a novel mechanism of action for chemotherapy-induced nausea and vomiting (CINV), and is recommended as a prophylactic by many international and domestic guidelines. However, domestic clinical trials of aprepitant have only been conducted using a single dose in patients who were treated with cisplatin(CDDP), and there is no evidence to support administration of aprepitant in divided doses. We administered aprepitant in divided doses to patients who were also being treated with cisplatin, ifosfamide, and irinotecan(CIC), and had CINV due to prophylactic administration of a 5-HT3 receptor antagonist and dexamethasone. This was done in order to evaluate the antiemetic effect of aprepitant. The patients with"No vomiting"increased significantly from 25% to 83%, and the"Days with nausea"in patients also decreased significantly. Consequently, administration of aprepitant in addition to current antiemetic therapy in divided doses, as well as in single doses, exhibited a greater antiemetic effect in CDDP-treated patients.

Published
2013

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