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1. Epidemiology of ataxia and hereditary spastic paraplegia in Spain: A cross-sectional study

Author

Ortega Suero, G., Abenza Abildúa, M.J., Serrano Munuera, C., Rouco Axpe, I., Arpa Gutiérrez, F.J., Adarmes Gómez, A.D., Rodríguez de Rivera, F.J., Quintans Castro, B., Posada Rodríguez, I., Vadillo Bermejo, A., Domingo Santos, Á., Blanco Vicente, E., Infante Ceberio, I., Pardo Fernández, J., Costa Arpín, E., Painous Martí, C., Muñoz García, J.E., Mir Rivera, P., Montón Álvarez, F., Bataller Alberola, L., Gascón Bayarri, J., Casasnovas Pons, C., Vélez Santamaría, V., López de Munain, A., Fernández-Eulate, G., Gazulla Abío, J., Sanz Gallego, I., Rojas Bartolomé, L., Ayo Martín, Ó., Segura Martín, T., González Mingot, C., Baraldés Rovira, M., Sivera Mascaró, R., Cubo Delgado, E., Echavarría Íñiguez, A., Vázquez Sánchez, F., Bártulos Iglesias, M., Casadevall Codina, M.T., Martínez Fernández, E.M., Labandeira Guerra, C., Alemany Perna, B., Carvajal Hernández, A., Fernández Moreno, C., Palacín Larroy, M., Caballol Pons, N., Ávila Rivera, A., Navacerrada Barrero, F.J., Lobato Rodríguez, R., and Sobrido Gómez, M.J.

Published
2023
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2. Mapa epidemiológico transversal de las ataxias y paraparesias espásticas hereditarias en España

Author

Ortega Suero, G., Abenza Abildúa, M.J., Serrano Munuera, C., Rouco Axpe, I., Arpa Gutiérrez, F.J., Adarmes Gómez, A.D., Rodríguez de Rivera, F.J., Quintans Castro, B., Posada Rodríguez, I., Vadillo Bermejo, A., Domingo Santos, Á., Blanco Vicente, E., Infante Ceberio, I., Pardo Fernández, J., Costa Arpín, E., Painous Martí, C., Muñoz, J.E., Mir Rivera, P., Montón Álvarez, F., Bataller Alberola, L., Gascón Bayarri, J., Casasnovas Pons, C., Vélez Santamaría, V., López de Munain, A., Fernández-Eulate, G., Gazulla Abío, J., Sanz Gallego, I., Rojas Bartolomé, L., Ayo Martín, Ó., Segura Martín, T., González Mingot, C., Baraldés Rovira, M., Sivera Mascaró, R., Cubo Delgado, E., Echavarría Íñiguez, A., Vázquez Sánchez, F., Bártulos Iglesias, M., Casadevall Codina, M.T., Martínez Fernández, E.M., Labandeira Guerra, C., Alemany Perna, B., Carvajal Hernández, A., Fernández Moreno, C., Palacín Larroy, M., Caballol Pons, N., Ávila Rivera, A., Navacerrada Barrero, F.J., Lobato Rodríguez, R., and Sobrido Gómez, M.J.

Published
2023
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3. Estimated GFR and the Effect of Intensive Blood Pressure Lowering After Acute Intracerebral Hemorrhage

Author

Anderson, C.S., Chalmers, J., Arima, H., Davis, S., Heeley, E., Huang, Y., Lavados, P., Neal, B., Parsons, M.W., Lindley, R., Morgenstern, L., Robinson, T., Stapf, C., Tzourio, C., Wang, J.G., Chen, S., Chen, X.Y., Cui, L., Liu, Z., Lu, C., Wang, J., Wu, S., Xu, E., Yang, Q., Zhang, C., Zhang, J., Beer, R., Schmutzhard, E., Redondo, P., Kaste, M., Soinne, L., Tatlisumak, T., Wartenberg, K., Ricci, S., Klijn, K., Azevedo, E., Chamorro, A., Arnold, M., Fischer, U., Kaul, S., Pandian, J., Boyini, H., Singh, S., Rabinstein, A.A., Estol, C., Silva, G., Olavarria, V.V., Robinson, T.G., Simes, R.J., Bousser, M.-G., Hankey, G., Jamrozik, K., Johnston, S.C., Li, S., Bailey, K., Cheung, T., Delcourt, C., Chintapatla, S., Ducasse, E., Erho, T., Hata, J., Holder, B., Knight, E., Leroux, M., Sassé, T., Odgers, E., Walsh, R., Wolfowicz, Z., Chen, G., Fuentes, S., Peng, B., Schneble, H.-M., Wang, M.-X., Billot, L., Heritier, S., Li, Q., Woodward, M., Abimbola, S., Anderson, S., Chan, E., Cheng, G., Chmielnik, P., Leighton, S., Liu, J.-Y., Rasmussen, B., Saxena, A., Tripathy, S., Armenis, M., Baig, M.A., Naidu, B., Starzec, G., Steley, S., Moles, A., Ruiz, A., Zimmermann, M., Marinho, J., Alves, S., Angelim, R., Araujo, J., Kawakami, L., Bustos, C., Gonzalez, F., Munoz Venturelli, P., Chen, X., Jia, R., Li, N., Qu, S., Shu, Y., Song, A., Sun, J., Xiao, J., Zhao, Y., Huang, Q., Vicaut, E., Chamam, A., Viaud, M.-C., Dert, C., Fiedler, U., Jovis, V., Kabla, S., Marchand, S., Pena, A., Rochaud, V., Mallikarjuna, K., Hasan, N., Berge, E., Sandset, E.C., Forårsveen, A.S., Richardson, D., Kumar, T., Lewin, S., Poulter, N., Field, J., Anjum, A., Wilson, A., Perelmuter, H., Agarie, A.M., Barboza, A.G., Recchia, L.A., Miranda, I.F., Rauek, S.G., Duplessis, R.J., Dewey, H., Walker, L., Petrolo, S., Bladin, C., Sturm, J., Crimmins, D., Griffiths, D., Schutz, A., Zenteno, V., Miteff, F., Spratt, N., Kerr, E., Levi, C.R., Phan, T.G., Ma, H., Sanders, L., Moran, C., Wong, K., Read, S., Henderson, R., Wong, A., Hull, R., Skinner, G., Hand, P., Yan, B., Tu, H., Campbell, B., Blacker, D.J., Wijeratne, T., Pathirage, M., Jasinararchchi, M., Matkovic, Z., Celestino, S., Gruber, F., Vosko, M.R., Diabl, E., Rathmaier, S., Pfausler, B., Helbok, R., Fazekas, F., Fischer, R., Poltrum, B., Zechner, B., Trummer, U., Rutgers, M.P., Peeters, A., Dusart, A., Duray, M.-C., Parmentier, C., Ferrao-Santos, S., Brouns, R., De Raedt, S., De Smedt, A., VanHooff, R.-J., De Keyser, J., Martins, S.C.O., de Almeida, A.G., Broudani, R., Titton, N.F., de Freitas, G.R., Cardoso, F.M., Giesel, L.M., Lima, N.A., Jr, Ferraz de Almeida, A.C., Gomes, R.B., Borges dos Santos, T.S., Veloso Soares, E.M., Neto, O.L.A., Silva, G.S., Gomes, D.L., de Carvalho, F.A., Miranda, M., Marques, A., Zétola, V.F., de Matia, G., Lange, M.C., Montes, J., Reccius, A., Soto, A., Rivas, R., Klapp, C., Illanes, S., Aguilera, C., Castro, A., Figueroa, C., Benavides, J., Salamanca, P., Concha, M.C., Pajarito, J., Araya, P., Guerra, F., Li, Y., Liu, G., Wang, B., Chong, Y., He, M., Wang, L., Liu, J., Zhang, X., Lai, C., Jiang, H., Cui, S., Tao, Q., Zhang, Y., Yao, S., Xu, M., Xiao, H., Hu, J., Tang, J., Ji, H., Jiang, M., Yu, F., Yang, X., Guo, X., Wang, Y., Wu, L., Gao, Y., Sun, D., Huang, X., Liu, L., Li, P., Jiang, Y., Li, H., Lu, H., Zhou, J., Yuan, C., Qi, X., Qiu, F., Qian, H., Wang, W., Sun, W., Li, F., Liu, R., Peng, Q., Ren, Z., Fan, C., Wang, H., Wang, T., Shi, F., Duan, C., Chen, Z., Tan, X., Zhao, Z., Chen, J., Han, T., Zhang, L., Hu, Q., Hou, Q., Zhao, X., Zeng, G., Ma, L., Wang, F., Zeng, L., Guo, Z., Fu, Y., Song, Y., Tai, L., Liu, X., Su, X., Yang, Y., Dong, R., Xu, Y., Tian, S., Cheng, S., Su, L., Xie, X., Xu, T., Geng, D., Yan, X., Fan, H., Zhao, N., Wang, S., Yang, J., Yan, M., Li, L., Li, Z., Xu, X., Lian, Y., Sun, H., Liu, D., Wang, N., Tang, Q., Han, Z., Feng, L., Cui, Y., Tian, J., Chang, H., Sun, X., Liu, C., Wen, Z., Lin, Q., Sun, L., Hu, B., Zou, M., Bao, Q., Lin, X., Zhao, L., Tian, X., Wang, X., Li, X., Hao, L., Duan, Y., Wang, R., Wei, Z., Ren, S., Ren, H., Dong, Y., Cheng, Y., Liu, W., Han, J., Zhang, Z., Zhu, J., Qian, J., Sun, Y., Liu, K., Long, F., Peng, X., Zhang, Q., Yuan, Z., Wang, C., Huang, M., He, P., You, Y., Xia, J., Zhou, L., Hou, Y., Qi, Y., Mei, L., Lu, R., Ping, L., Zhou, S., Zhang, S., Zou, R., Guo, J., Li, M., Wei, W., Curtze, S., Saarela, M., Strbian, D., Scheperjans, F., De Broucker, T., Henry, C., Cumurciuc, R., Ibos-Augé, N., Zéghoudi, A.-C., Pico, F., Dereeper, O., Simian, M.-C., Boisselier, C., Mahfoud, A., Timsit, S., Merrien, F.M., Guillon, B., Sevin, M., Herisson, F., Magne, C., Ameri, A., Cret, C., Stefanizzi, S., Klapzcynski, F., Denier, C., Sarov-Riviere, M., Reiner, P., Mawet, J., Hervé, D., Buffon, F., Touzé, E., Domigo, V., Lamy, C., Calvet, D., Pasquini, M., Alamowitch, S., Favrole, P., Muresan, I.-P., Crozier, S., Rosso, C., Pires, C., Leger, A., Deltour, S., Cordonnier, C., Henon, H., Rossi, C., Zuber, M., Bruandet, M., Tamazyan, R., Join-Lambert, C., Juettler, E., Krause, T., Maul, S., Endres, M., Jungehulsing, G.J., Hennerici, M., Griebe, M., Sauer, T., Knoll, K., Huber, R., Knauer, K., Knauer, C., Raubold, S., Schneider, H., Hentschel, H., Lautenschläger, C., Schimmel, E., Dzialowski, I., Foerch, C., Lorenz, M., Singer, O., Meyer dos Santos, I.M.R., Hartmann, A., Hamann, A., Schacht, A., Schrader, B., Teíchmann, A., Wartenberg, K.E., Mueller, T.J., Jander, S., Gliem, M., Boettcher, C., Rosenkranz, M., Beck, C., Otto, D., Thomalla, G., Cheng, B., Wong, K.S., Leung, T.W., Soo, Y.O.Y., Prabhakar, S., Kesavarapu, S.R., Gajjela, P.K., Chenna, R.R., Ummer, K., Basheer, M., Andipet, A., Jagarlapudi, M.K.M., Mohammed, A.U.R., Pawar, V.G., Eranki, S.S.K., Singh, Y., Akhtar, N., Borah, N.C., Ghose, M., Choudhury, N., Ichaporia, N.R., Shendge, J., Khese, S., Pamidimukkala, V., Inbamuthaiah, P., Nuthakki, S.R., Tagallamudi, N.M.R., Gutti, A.K., Khurana, D., Kesavarapu, P., Jogi, V., Garg, A., Samanta, D., Sarma, G.R.K., Nadig, R., Mathew, T., Anandan, M.A., Caterbi, E., Zini, A., Cavazzuti, M., Casoni, F., Pentore, R., Falzone, F., Mazzoli, T., Greco, L.M., Menichetti, C., Coppola, F., Cenciarelli, S., Gallinella, E., Mattioni, A., Condurso, R., Sicilia, I., Zampolini, M., Corea, F., Barbi, M., Proietti, C., Toni, D., Pieroni, A., Anzini, A., Falcou, A., Demichele, M., Klijn, C.J.M., Tveiten, A., Thortveit, E.T., Pettersen, S., Holand, N., Hitland, B., Johnsen, S.H., Eltoft, A., Wasay, M., Kamal, A., Iqrar, A., Ali, L., Begum, D., Gama, G., Fonseca, L., Moreira, G., Veloso, L.M., Pinheiro, D., Paredes, L., Rozeira, C., Gregorio, T., Segura Martin, T., Ayo, O., Garcia-Garcia, J., Feria Vilar, I., Gómez Fernández, I., Amaro, S., Urra, X., Obach, V., Cervera, A., Silva, Y., Serena, J., Castellanos, M., Terceno, M., Van Eendenburg, C., Weck, A., Findling, O., Lüdi, R., Warburton, E.A., Day, D., Butler, N., Bumanlag, E., Caine, S., Steele, A., Osborn, M., Dodd, E., Murphy, P., Esisi, B., Brown, E., Hayman, R., Baliga, V.K.V., Minphone, M., Kennedy, J., Reckless, I., Pope, G., Teal, R., Michael, K., Manawadu, D., Kalra, L., Lewis, R., Mistry, B., Cattermole, E., Hassan, A., Mandizvidza, L., Bamford, J., Brooks, H., Bedford, C., Whiting, R., Baines, P., Hussain, M., Harvey, M., Fotherby, K., McBride, S., Bourke, P., Morgan, D., Jennings-Preece, K., Price, C., Huntley, S., Riddell, V.E., Storey, G., Lakey, R.L., Subramanian, G., Jenkinson, D., Kwan, J., David, O., Tiwari, D., James, M., Keenan, S., Eastwood, H., Shaw, L., Kaye, P., Button, D., Madigan, B., Williamson, D., Dixit, A., Davis, J., Hossain, M.O., Ford, G.A., Parry-Jones, A., O'Loughlin, V., Jarapa, R., Naing, Z., Lovelock, C., O'Reilly, J., Khan, U., Bhalla, A., Rudd, A., Birns, J., Werring, D.J., Law, R., Perry, R., Jones, I., Erande, R., Roffe, C., Natarajan, I., Ahmad, N., Finney, K., Lucas, J., Mistri, A., Eveson, D., Marsh, R., Haunton, V., Fugate, J.E., Lepore, S.W., Zheng, Danni, Sato, Shoichiro, Arima, Hisatomi, Heeley, Emma, Delcourt, Candice, Cao, Yongjun, Chalmers, John, and Anderson, Craig S.

Published
2016
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7. 20491. SÍNDROME DE LA OREJA ROJA SECUNDARIO, A PROPÓSITO DE UN CASO

Author

Torres López, L., Martínez Fernández, I., Restrepo Carvajal, L., Cuenca Juan, F., Ocaña Mora, B., Sánchez Morales, L., Fernández Usero, A., López Rojo, Á., Hernández Fernández, F., Payá Montes, M., Olmeda, C., Molina Nuevo, J., Alcahut Rodríguez, C., Ayo Martín, Ó., Serrano Serrano, B., and Segura Martín, T.

Published
2024
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8. 21247. VALOR PRONÓSTICO DE LA PRESENCIA DE HIPERDENSIDAD EN LA TC DE CONTROL EN LOS PACIENTES CON ICTUS ISQUÉMICO TRATADOS MEDIANTE TROMBECTOMÍA MECÁNICA

Author

Ocaña Mora, B., Ayo Martín, Ó., Hernández Fernández, F., Molina Nuevo, J., García García, J., Payá Montes, M., Serrano Serrano, B., Palao Rico, M., Collado Jiménez, R., Lozano Setién, E., Sánchez Morales, L., Martínez Fernández, I., Restrepo Carvajal, L., Cuenca Juan, F., and Segura Martín, T.

Published
2024
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9. 20068. ANGIOPATÍA AMILOIDE CEREBRAL IATRÓGENA Y COPATOLOGÍA CON ENFERMEDAD DE ALZHEIMER TRAS ANTECEDENTE NEUROQUIRÚRGICO. DESCRIPCIÓN DE UNA SERIE DE CASOS

Author

Martínez Fernández, I., Hernández Fernández, F., Barbella, R., Feria Vilar, I., Ayo, Ó., García García, J., Collado, R., Andrés López, A., Barrena, C., Serrano, G., Lozano, E., López, L., Sánchez Larsen, Á., Serrano, B., González Villar, E., Restrepo Carvajal, L., Cuenca Juan, F., Ocaña Mora, B., Sánchez Morales, L., Torres López, L., and Segura Martín, T.

Published
2024
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13. 21238. VALOR PREDICTIVO DE LA DILATACIÓN AURICULAR PARA LA DETECCIÓN DE FIBRILACIÓN AURICULAR OCULTA EN UNA SERIE MULTICÉNTRICA DE PACIENTES ESUS CON MONITORIZACIÓN TEMPRANA Y CONTINUA DE ECG

Author

Ayo Martín, Ó., Rieta, J., Payá Montes, M., López Neyra, I., Hidalgo Olivares, V., Guerra Luján, L., Lobato Casado, P., Flores Barragán, J., de Lera Alfonso, M., González Feito, P., Durán Sepúlveda, V., Serrano Serrano, B., Palao Rico, M., Segura Martín, T., and Alcaraz Martínez, R.

Published
2024
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14. Health care resources for stroke patients in Spain, 2010: Analysis of a national survey by the Cerebrovascular Diseases Study Group

Author

López Fernández, J.C., Arenillas Lara, J., Calleja Puerta, S., Botia Paniagua, E., Casado Naranjo, I., Deyá Arbona, E., Escribano Soriano, B., Freijo Guerrero, M.M., Geffners Sclarsky, D., Gil Núñez, A., Gil Peralta, A., Gil Pujadas, A., Gómez Escalonilla, C., Lago Martin, A., Larracoechea Jausoro, J., Legarda Ramírez, I., Maestre Moreno, J., Manciñeiras Montero, J.L., Mola Caballero De Rodas, S., Moniche Álvarez, F., Muñoz Arrondo, R., Vidal Sánchez, J.A., Purroy García, F., Ramírez Moreno, J.M., Rebollo Álvarez Amandi, M., Rubio Borrego, F., Segura Martin, T., Tejada García, J., Tejero Juste, C., and Masjuan Vallejo, J.

Published
2011
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15. Recursos asistenciales en ictus en España 2010: análisis de una encuesta nacional del Grupo de Estudio de Enfermedades Cerebrovasculares

Author

López Fernández, J.C., Arenillas Lara, J., Calleja Puerta, S., Botia Paniagua, E., Casado Naranjo, I., Deyá Arbona, E., Escribano Soriano, B., Freijo Guerrero, M.M., Geffners Sclarsky, D., Gil Núñez, A., Gil Peralta, A., Gil Pujadas, A., Gómez Escalonilla, C., Lago Martin, A., Larracoechea Jausoro, J., Legarda Ramírez, I., Maestre Moreno, J., Manciñeiras Montero, J.L., Mola Caballero De Rodas, S., Moniche Álvarez, F., Muñoz Arrondo, R., Vidal Sánchez, J.A., Purroy García, F., Ramírez Moreno, J.M., Rebollo Álvarez Amandi, M., Rubio Borrego, F., Segura Martin, T., Tejada García, J., Tejero Juste, C., and Masjuan Vallejo, J.

Published
2011
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16. Epidemiology of ataxia and hereditary spastic paraplegia in Spain: a cross-sectional study

Author

Ortega Suero G, Abenza Abildúa MJ, Serrano Munuera C, Rouco Axpe I, Arpa Gutiérrez FJ, Adarmes Gómez AD, Rodríguez de Rivera FJ, Quintans Castro B, Posada Rodríguez I, Vadillo Bermejo A, Domingo Santos Á, Blanco Vicente E, Infante Ceberio I, Pardo Fernández J, Costa Arpín E, Painous Martí C, Muñoz JE, Mir Rivera P, Montón Álvarez F, Bataller Alberola L, Gascón Bayarri J, Casasnovas Pons C, Vélez Santamaría V, López Munain A, Fernández García Eulate G, Gazulla Abío J, Sanz Gallego I, Rojas Bartolomé L, Ayo Martín Ó, Segura Martín T, González Mingot C, Baraldés Rovira M, Sivera Mascaró R, Cubo Delgado E, Echevarría Íñiguez A, Vázquez Sánchez F, Bártulos Iglesias M, Casadevall Codina MT, Martínez Fernández EM, Labandeira Guerra C, Alemany Perna B, Carvajal Hernández A, Fernández Moreno C, Palacín Larroy M, Caballol Pons N, Ávila Rivera A, Navacerrada Barrero FJ, Lobato Rodríguez R, and Sobrido Gómez MJ

Subjects
Ataxias, Paraparesias espásticas hereditarias, congenital, hereditary, and neonatal diseases and abnormalities, Genetic map, Epidemiology, Materials Chemistry, Genetics, Hereditary spastic paraplegia, Epidemiología, Mapa genético, Ataxia, Genética, nervous system diseases
Abstract

INTRODUCTION: Ataxia and hereditary spastic paraplegia are rare neurodegenerative syndromes. We aimed to determine the prevalence of these disorders in Spain in 2019. PATIENTS AND METHODS: We conducted a cross-sectional, multicentre, retrospective, descriptive study of patients with ataxia and hereditary spastic paraplegia in Spain between March 2018 and December 2019. RESULTS: We gathered data from a total of 1.809 patients from 11 autonomous communities, provided by 47 neurologists or geneticists. Mean (SD) age in our sample was 53.64 (20.51) years; 920 patients were men (50.8%) and 889 were women (49.2%). The genetic defect was unidentified in 920 patients (47.6%). A total of 1371 patients (70.9%) had ataxia and 562 (29.1%) had hereditary spastic paraplegia. Prevalence rates for ataxia and hereditary spastic paraplegia were estimated at 5.48 and 2.24 cases per 100 000 population, respectively. The most frequent type of dominant ataxia in our sample was SCA3, and the most frequent recessive ataxia was Friedreich ataxia. The most frequent type of dominant hereditary spastic paraplegia in our sample was SPG4, and the most frequent recessive type was SPG7. CONCLUSIONS: In our sample, the estimated prevalence of ataxia and hereditary spastic paraplegia was 7.73 cases per 100 000 population. This rate is similar to those reported for other countries. Genetic diagnosis was not available in 47.6% of cases. Despite these limitations, our study provides useful data for estimating the necessary healthcare resources for these patients, raising awareness of these diseases, determining the most frequent causal mutations for local screening programmes, and promoting the development of clinical trials.

Published
2020

24. ¿Cómo es el ictus del paciente que ingresamos? Factores de decisión en la hospitalización

Author

López-López F, Sobrino-Vega Mp, Vivancos-Mora J, del Ser-Quijano T, Segura-Martín T, Figuerola-Roig T, Fernández-García C, Monforte-Dupret C, and León-Colombo T

Subjects
Pediatrics, medicine.medical_specialty, Stroke patient, business.industry, Stroke scale, Atrial fibrillation, General Medicine, Logistic regression, medicine.disease, Epidemiology, Cohort, medicine, Observational study, cardiovascular diseases, Neurology (clinical), business, Stroke
Abstract

OBJECTIVE To study main factors determining medical decision in admitting patients with acute cerebrovascular disease (ACVD). PATIENTS AND METHODS This is an observational and transversal study. We analyze a hospitalary cohort made by all consecutive patients with ACVD coming to Emergency Room to Hospital Universitario de la Princesa during 1 year. Neurologist on call made on his/her own decision to admit the patient to hospital. Clinical and epidemiological characteristics of those patients admitted with those who went home are compared. RESULTS 517 patients were studied, 147 had transient ischemic attacks (TIA) and 370 had a stroke, 12.3% TIA and 68.4% stroke patients were hospitalized. Age, Canadian Stroke Scale (CSS) on admission, subtype of stroke, atrial fibrillation and abnormal EKG, old lesions in CT, previous TIA and/or CVD, diminished conscious level, orientation and language, sphincter control and evolution time greater than 48 hours were statistically significative in deciding admission. Logistic regression analysis (84.2% total predictive value) showed independent predictive value in age, CSS, previous CVD and some subtypes of stroke (ischemic non lacunar and hemorrhage). CONCLUSIONS We hospitalize younger patients, with a worse clinical condition and overall hemorrhagic stroke. The percentage of admissions among TIA patients is low. On the other hand, date, time and physicians-team features do not affect the percentage of admissions.

Published
1998
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25. Cerebral hemodynamic changes at basilar artery in patients with obstructive sleep apnea syndrome. A case-control study.

Author

Jiménez Caballero, P. E., Coloma Navarro, R., Segura Martín, T., and Ayo Martín, O.

Subjects
HEMODYNAMICS, BASILAR artery, SLEEP apnea syndromes, POLYSOMNOGRAPHY, HEART beat, SYMPTOMS, COMPARATIVE studies, PATIENTS
Abstract

Introduction Obstructive sleep apnea syndrome ( OSAS) is characterized in polysomnography by recurrent airflow obstruction during sleep. The underlying pathogenic mechanisms of neuropsychological and cerebrovascular events in patients with OSAS have not been clarified unequivocally. Material and methods Case-control study to evaluate the cerebral vasomotor reactivity assessed by breath-holding maneuver at basilar artery in patients with OSAS compared to control subjects. Results The study included 76 patients with OSAS and 76 controls. Vascular risk factors (arterial hypertension, diabetes mellitus, hypercholesterolemia, smoking), age, gender, coronary, and peripheral arterial diseases were similar in both groups. Patients with OSAS had breath-holding test values (31.9 ± 13.35%) lower than controls (39.06 ± 13.16%), ( P = 0.001). Patients with OSAS had higher systolic and diastolic blood pressure both basal and apnea and also a higher basal heart rate. Conclusions Altered cerebral hemodynamics together with increased blood pressure values in patients with OSAS may play a role in the association between this disease and the development of cerebrovascular events. This implies that this disease should be identified through guide symptoms such as snoring, sleep apnea, and daytime sleepiness in all patients who consult for these symptoms to reduce the number of cerebrovascular events. [ABSTRACT FROM AUTHOR]

Published
2014
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26. Mapa epidemiológico transversal de las ataxias y paraparesias espásticas hereditarias en España

Author

Ortega Suero, G., Abenza Abildúa, M.J., Serrano Munuera, C., Rouco Axpe, I., Arpa Gutiérrez, F.J., Adarmes Gómez, A.D., Rodríguez Rivera, F.J., Quintans Castro, B., Posada Rodríguez, I., Vadillo Bermejo, A., Domingo Santos, Á., Blanco Vicente, E., Infante Ceberio, I., Pardo Fernández, J., Costa Arpín, E., Painous Martí, C., Muñoz, J.E., Mir Rivera, P., Montón Álvarez, F., Bataller Alberola, L., Gascón Bayarri, J., Casasnovas Pons, C., Vélez Santamaría, V., López Munain, A., Fernández García Eulate, G., Gazulla Abío, J., Sanz Gallego, I., Rojas Bartolomé, L., Ayo Martín, Ó., Segura Martín, T., González Mingot, C., Baraldés Rovira, M., Sivera Mascaró, R., Cubo Delgado, E., Echevarría Íñiguez, A., Vázquez Sánchez, F., Bártulos Iglesias, M., Casadevall Codina, M.T., Martínez Fernández, E.M., Lavandeira Suárez, C., Alemany Perna, B., Carvajal Hernández, A., Fernández Moreno, C., Palacín Larroy, M., Caballol Pons, N., Ávila Rivera, A., Navacerrada Barrero, F.J., Lobato Rodríguez, R., and Sobrido Gómez, M.J.

Abstract

Las ataxias (AT) y paraparesias espásticas hereditarias (PEH) son síndromes neurodegenerativos raros. Nos proponemos conocer la prevalencia de las AT y PEH en España en 2019.

Published
2021
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28. Cerebral hemodynamic changes at basilar artery in obstructive sleep apnea syndrome after continuous positive airway pressure treatment.

Author

Jiménez Caballero PE, Coloma Navarro R, Ayo Martín O, and Segura Martín T

Subjects
Adult, Basilar Artery diagnostic imaging, Blood Pressure physiology, Body Mass Index, Continuous Positive Airway Pressure, Female, Heart Rate physiology, Humans, Male, Middle Aged, Sleep Apnea, Obstructive diagnostic imaging, Sleep Apnea, Obstructive physiopathology, Treatment Outcome, Ultrasonography, Basilar Artery physiopathology, Hemodynamics physiology, Sleep Apnea, Obstructive therapy
Abstract

Background: Cerebral vasoreactivity in obstructive sleep apnea syndrome is altered. Continuous positive airway pressure is effective in the reduction of the occurrence of apneas. We studied whether this treatment also improves cerebral vasoreactivity., Methods: The breath-holding maneuver was performed and assessed by apnea test with transcranial Doppler in the basilar artery. After 2 years of continuous positive airway pressure treatment, the test was repeated., Results: There is an improvement in the apnea test after continuous positive airway pressure. There are increases in the pulsatility index, diastolic blood pressure, and basal heart rate. The improvement in the apnea test depends on the body mass index of the patient., Conclusions: Cerebral vasoreactivity as measured by the apnea test improves after 2 years of continuous positive airway pressure. This improvement depends of the body mass index of the patient., (Copyright © 2013 National Stroke Association. Published by Elsevier Inc. All rights reserved.)

Published
2013
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29. Cerebral hemodynamic changes in obstructive sleep apnea syndrome after continuous positive airway pressure treatment.

Author

Jiménez Caballero PE, Coloma Navarro R, Ayo Martín O, and Segura Martín T

Subjects
Adult, Blood Flow Velocity physiology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Middle Cerebral Artery diagnostic imaging, Middle Cerebral Artery physiopathology, Polysomnography, Prospective Studies, Sleep Apnea, Obstructive diagnostic imaging, Ultrasonography, Doppler, Transcranial, Vascular Resistance physiology, Brain blood supply, Continuous Positive Airway Pressure, Hemodynamics physiology, Sleep Apnea, Obstructive physiopathology, Sleep Apnea, Obstructive therapy
Abstract

Background: Patients with obstructive sleep apnea syndrome (OSAS) are at increased risk for cerebrovascular diseases. The underlying mechanisms remain obscure. It may occur through a reduction in cerebral vascular reactivity. Continuous positive airway pressure (CPAP) is effective in reducing the occurrence of apneas. We hypothesized that treatment with CPAP improves cerebral vascular reactivity., Methods: This is a prospective study with OSAS patients. The apnea test (ApT) was calculated as an increase of mean artery velocity during apnea: [Artery velocity in apnea minus Resting artery velocity]/Resting artery velocity expressed as percentage. After 2 years of CPAP treatment, the test was repeated., Results: Seventy-six patients represented the study pool. After 2 years of treatment with CPAP, we were able to conduct a reassessment in 65 patients. Of the 65 patients who finished the clinical study, 56 were men, and 9 were women, with an average age of 48.1 ± 10.4 years. There was an improvement in the ApT after CPAP treatment (30.8 ± 12.1 vs 39.8 ± 15.1; p:0.000). The values of cerebral blood flow velocities, diastolic blood pressure in apnea, and basal heart rate decreased., Conclusions: Cerebral vascular reactivity in OSAS patients measured by ApT improved after 2 years of CPAP.

Published
2013
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30. [Color duplex and giant cell arteritis].

Author

García-García J, Ayo Martín O, and Segura Martín T

Subjects
Aged, 80 and over, Cerebrovascular Circulation, Color, Humans, Regional Blood Flow, Giant Cell Arteritis diagnosis, Giant Cell Arteritis pathology, Ultrasonography, Doppler, Color
Published
2008

31. Cardioembolic stroke secondary to non-bacterial endocarditis in Wegener disease.

Author

Jiménez Caballero PE and Segura Martín T

Subjects
Adult, Echocardiography methods, Endocarditis, Bacterial pathology, Granulomatosis with Polyangiitis pathology, Humans, Magnetic Resonance Angiography methods, Male, Middle Cerebral Artery pathology, Endocarditis, Bacterial complications, Granulomatosis with Polyangiitis complications, Stroke etiology
Abstract

Wegener granulomatosis is a systemic vasculitis that mainly affects the upper and lower respiratory tract and the kidneys. The presence of an ischemic stroke in this disease is very rare. A 40-year-old man, smoker with cavitated lesions in both lungs, and inflammation in the nasal mucosa and vocal cords developed an ischemic stroke in the left middle cerebral artery, with the etiological study showing non-bacterial endocarditis. Non-bacterial endocarditis can appear in patients with Wegener granulomatosis, with this being the first case of this cardioembolism reported in this disease.

Published
2007
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33. [The normal values of the haemodynamic reserve (HR) evaluated by the CO2 test].

Author

Alvarez Pérez FJ, Segura Martín T, Serena Leal J, Osuna Pulido T, Castellanos Rodrigo M, Silva Blas Y, and Dávalos Errando A

Subjects
Adolescent, Adult, Aged, Female, Humans, Male, Middle Aged, Reference Values, Ultrasonography methods, Carbon Dioxide metabolism, Cerebrovascular Circulation physiology, Hemodynamics physiology
Abstract

Background: The cerebral haemodynamic reserve (HR) is a recognised predictive factor of brain ischaemia in subjects with carotid stenosis. Our objective is to establish normal parameters which may be used for comparison with deficit states., Subjects and Method: The haemodynamic reserve was calculated in healthy subjects who had no evidence of previous carotid, haematological or cardiovascular pathologies. Subjects were asked to inhale CO2. The HR was then calculated as a percentage of the increase in the mean velocity in the Silvian artery for each millimetre of mercury increase of the end-tidal CO2. The median and percentiles 5 and 95 were calculated for each hemisphere, sex and age group., Results: 100 subjects were studied (45 men and 55 women, mean age 51.6 years, range 18-79). Normal HR value was defined as percentile 5, with a value of 2% for men, and 2.5% for women. The only adverse reaction was dyspnea in 2 subjects., Conclusions: Values for the haemodynamic reserve of healthy subjects, which may serve as a reference for other ultrasonography laboratories, are established from an extensive control group.

Published
2002

34. [Early recurrence of ischaemia in a patient with cerebral haemorrhage due to moya moya disease].

Author

Segura Martín T, Fernández P, and Zorita MD

Subjects
Adult, Angiography, Brain pathology, Brain Ischemia pathology, Brain Ischemia physiopathology, Cerebral Hemorrhage pathology, Female, Humans, Moyamoya Disease pathology, Moyamoya Disease physiopathology, Recurrence, Tomography, X-Ray Computed, White People, Brain Ischemia etiology, Cerebral Hemorrhage etiology, Moyamoya Disease complications
Published
2001

36. [Urinary incontinence in patients with acute ictus].

Author

Suñer Soler R, Vega Iñigo R, García Garrido L, García Gutiérrez T, Mascort Toral Z, Segura Martín T, and Dávalos Errando A

Subjects
Acute Disease, Aged, Female, Geriatric Assessment, Humans, Male, Prognosis, Prospective Studies, Recovery of Function, Stroke complications, Stroke Rehabilitation, Urinary Incontinence etiology
Abstract

This project won the "Ausonia" Incontinence First Prize among those projects submitted during 1999. This article analyzes the prevalence of urinary incontinence among patients diagnosed as suffering acute ictus after 3 months, 6 months and 12 months. The authors also investigate those factors associated with acute ictus incontinence, how incontinence influences a patient's evolution, and how incontinence affects the environment where recuperation occurs, at home or in an institution, while the patient is recovering. The results confirm that acute urinary incontinence is a forecasting factor, independent of the poor middle and long range functional prognosis, and that the potential prognosis is superior than the seriousness of the neurological deficit at the moment a patient enters a hospital.

Published
2000

37. [What sort of stroke requires patient admittance to the hospital? Factors for deciding on hospitalization].

Author

León-Colombo T, Vivancos-Mora J, del Ser-Quijano T, Fernández-García C, Segura-Martín T, Monforte-Dupret C, Figuerola-Roig T, Sobrino-Vega MP, and López-López F

Subjects
Age Factors, Aged, Cohort Studies, Emergency Service, Hospital, Female, Humans, Ischemic Attack, Transient therapy, Male, Middle Aged, Neurobehavioral Manifestations, Orientation, Regression Analysis, Time Factors, Brain Ischemia therapy, Patient Admission standards
Abstract

Objective: To study main factors determining medical decision in admitting patients with acute cerebrovascular disease (ACVD)., Patients and Methods: This is an observational and transversal study. We analyze a hospitalary cohort made by all consecutive patients with ACVD coming to Emergency Room to Hospital Universitario de la Princesa during 1 year. Neurologist on call made on his/her own decision to admit the patient to hospital. Clinical and epidemiological characteristics of those patients admitted with those who went home are compared., Results: 517 patients were studied, 147 had transient ischemic attacks (TIA) and 370 had a stroke, 12.3% TIA and 68.4% stroke patients were hospitalized. Age, Canadian Stroke Scale (CSS) on admission, subtype of stroke, atrial fibrillation and abnormal EKG, old lesions in CT, previous TIA and/or CVD, diminished conscious level, orientation and language, sphincter control and evolution time greater than 48 hours were statistically significative in deciding admission. Logistic regression analysis (84.2% total predictive value) showed independent predictive value in age, CSS, previous CVD and some subtypes of stroke (ischemic non lacunar and hemorrhage)., Conclusions: We hospitalize younger patients, with a worse clinical condition and overall hemorrhagic stroke. The percentage of admissions among TIA patients is low. On the other hand, date, time and physicians-team features do not affect the percentage of admissions.

Published
1998

38. [Admission to hospital versus home care for stroke].

Author

León-Colombo T, Segura-Martín T, and Vivancos-Mora J

Subjects
Brain Ischemia epidemiology, Humans, Incidence, Prevalence, Spain epidemiology, Brain Ischemia rehabilitation, Home Nursing, Hospitalization
Abstract

The incidence and prevalence of cerebrovascular disease is very high. This is a major sanitary problem. There are no studies comparing the management of acute stroke as inpatient or outpatient, publications about each of these items are analyzed. General Practitioners may play a very important role, not only at the first step in the attention of stroke patients. Admission criteria for stroke and hospitalization span for its different ethiopathogenic types are revised.

Published
1997

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