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In this paper, we examine market-shaping literature that investigates how markets evolve over time. We focus on how controversial innovations gain acceptance as the result of the intentional strategies put into place by companies. We've carried a qualitative research based on secondary data collected from several online sources. Our study describes how a new packaging, can, had been introduced to the highly conservative market of wine in France. Our findings shed light on the opportunity for practitioners to implement controversial innovation in conservative markets and introduce a set of strategies to achieve such purpose. [ABSTRACT FROM AUTHOR]

The article discusses the analysis of real-world studies on CAR T-cell therapy in patients with relapsed/refractory large B-cell lymphomas. The study compares the outcomes of CAR T therapy based on intention-to-treat (ITT) and per protocol (PP) analyses, highlighting the importance of considering patients who undergo leukapheresis but do not receive the infusion. Results show varying response rates between ITT and PP populations, with differences influenced by factors like bridging therapy and study location. The study suggests the need for standardized data collection and the implementation of CAR T patient registries to assess treatment effectiveness comprehensively. [Extracted from the article]

Background: Serious adverse events (SAEs) are common in intensive care unit (ICU) patients. Reporting of SAEs in randomised clinical trials (RCTs) varies why underreporting is likely. We aim to describe the reporting of SAEs from 2020 onwards and to illustrate the recent reporting of SAEs published in major medical journals. Methods: We will conduct a methodological study assessing pharmacological interventions in RCTs including adult ICU patients. We will search 10 general medical and critical care journals in PubMed. We will include all RCTs published from 2020 onwards. The primary research question is how many RCTs report SAEs in the primary publication. Secondary research questions include how SAEs are reported in the primary publication either as (1) proportion of patients experiencing one or more SAE, (2) all single events occurred, or (3) both strategies combined. We will assess the association between the proportion of patients with reported SAEs and the following trial characteristics: multicentred versus single‐centre RCTs, industry‐sponsored versus academic‐sponsored, published trial protocol versus unpublished work, blinding, trials sample size, and RCTs focusing on COVID‐19 patients versus other populations. Discussion: The outlined methodological study will provide important information on the reporting of SAEs in recent drug trials in adult ICU patients. [ABSTRACT FROM AUTHOR]

Systematic reviews have witnessed significant growth across many fields, including education. In this article, we outline the background of this growth, highlight the tendency to focus on methodological considerations, and propose a framework to support education researchers in preparing systematic reviews with broad impact. We draw on our experience working with education stakeholders in Singapore and on international scholarship to propose a framework that supports education researchers in clarifying and specifying their aims and audiences and crafting syntheses of appropriate types. Our aim is that this framework, which includes examples illustrating four categories of reviews, acts as a reflective tool which researchers can use to maximize the utility, value, and potential impact of education research. [ABSTRACT FROM AUTHOR]

ABSTRACT Aim Design Methods Results Conclusions Impact Patient and Public Contribution The aim of this secondary analysis was to explore newly graduated perioperative nurses' experiences of transitioning to clinical practice to gain more in‐depth knowledge of this phenomenon.A qualitative explorative study of secondary data was used, and this study was reported following the Consolidated Criteria for Reporting Qualitative Research checklist.A secondary analysis of data collected between March 2019 and November 2020 via 16 semi‐structured interviews with newly graduated perioperative nurses. The interviews were conducted 3 to 5 months after they graduated from five different educational institutions in Norway and entered clinical practice as perioperative nurses. A three‐step phenomenological hermeneutical analysis inspired by Ricoeur's theory was applied: naïve reading, structural analysis and comprehensive understanding.We identified three themes: expectations of competence, facilitation for newly graduated perioperative nurses and the transition from being a student to a newly qualified perioperative nurse.Newly graduated perioperative nurses emphasised the critical role of supportive facilitation, manageable expectations and support from leaders and colleagues, which seemed essential for a successful transition to clinical practice.This study addresses knowledge essential for universities, universities colleges and clinical practice, specifically healthcare organisations, to understand the transition process for newly graduated perioperative nurses. This can support the establishment of improved practices to ensure patient safety via more specific education and mentoring and more accurate expectations of competence.No patient or public contribution. [ABSTRACT FROM AUTHOR]

In this article we propose a taxonomy describing various types of literature review or theoretical/conceptual articles. We distinguish each article type based on how well they address the summary and advocacy arguments inherent in all secondary scholarship. Understanding this taxonomy of review/theory scholarship is critical because our field encompasses theory, research, and design, and thus needs to be expansive in our understanding of scholarship, including secondary research. Some scholars conduct comprehensive/systematic reviews that answer the summary question of what we know. Meanwhile, other scholars develop conceptual frameworks that guide our future design and research by answering the advocacy question of what we should do. Many do not understand the differences between these different types of review scholarship, their roles, and the process and quality criteria for writing them. This limits our ability to teach students, review the variety of review and theory scholarship submitted to our journals, and propel our field forward. The taxonomy, scholarship process, and quality criteria presented in this article proposes a way forward in understanding the role of secondary scholarship in developing knowledge in our field. [ABSTRACT FROM AUTHOR]

Issue Addressed: The global epidemic of obesity is overtaking many parts of the world with the Pacific Islands at particular risk. Tonga population surveys identify significant increases in overweight and obesity with Social and Behaviour Change Communication (SBCC) offering opportunities for curbing the rise in non‐communicable diseases. Formative research was conducted during the Covid‐19 pandemic to assess stakeholder and program beneficiary needs and wants toward an obesity prevention SBCC strategy in Tonga. Methods: Semi‐structured interviews with 17 key informants and 18 focus group discussions (N = 168) were conducted in Tongatapu. Data analysis was conducted on Nvivo 2020 qualitative software with desk research of secondary data supporting in‐field findings. Results: Potential barriers to behavioural compliance included social/cultural norms, poor attitudes; low motivation and capability; and vulnerabilities of gender and other social determinants. Opportunities included the Tongan collective mindset and the desire for greater social interaction and fun. Strong political will to affect change was apparent with the need to consider targeting to youth, social mobilisation of communities through empowering messaging, and an integrated range of activities. Conclusions: Co‐design in the formative research process was able to be fostered via online communication processes to overcome the challenges of Covid‐19 travel restrictions. The innovative approach provided a number of learnings including identification of national and regional priorities and improved efficiencies in SBCC planning, implementation and evaluation. So What?: Formative research adopting co‐design approaches with stakeholders and program beneficiaries can provide optimal engagement and ownership in the SBCC strategy including insights into messaging approaches. [ABSTRACT FROM AUTHOR]

Summary: Osteonecrosis (ON) is a common complication of glucocorticoid‐based Hodgkin lymphoma (HL) treatment, but the natural evolution and prognosis of ON lesions remain poorly understood. We describe the radiological evolution of ON lesions identified in a Nordic population‐based cohort of paediatric HL patients. Magnetic resonance images of suspected ON lesions were centrally reviewed to confirm ON diagnosis and grade the ON lesions according to the Niinimäki classification. The study included 202 ON lesions in 46 patients, of which 77 were joint lesions. Follow‐up images were available for 146/202 lesions, with a mean follow‐up time of 28 months. During follow‐up, 71% of the lesions remained stable, 26% improved or resolved, and 3% progressed. A higher ON grade at diagnosis was associated with a lower likelihood of spontaneous resolution. The likelihood for resolution of ON decreased by 50% for each year of added patient age, when adjusted for sex, ON location, and symptoms. Hip ON showed less spontaneous improvement compared with other joints, and the risk for surgery was 13‐fold in hip ON. Grades 3–4 joint ON has the potential to either progress or resolve, warranting follow‐up in patients with severe symptoms. Research on secondary prevention should be directed at grade 3–4 joint ON. [ABSTRACT FROM AUTHOR]

While much research has been done regarding "palliative care" using retrospective cohort studies of large datasets, the data sources may not be capturing specialty palliative care services. This article aims to clarify what source data are used in such studies, how specialty palliative care services are determined to have been provided or not, and mismatches between the nature of the data and the interpretation of researchers. Major US data sources that are examined include cancer registries such as the National Cancer Database; health systems' internal data; state and nation-level hospital admissions data; and claims data from Medicare and commercial payers. Problematic studies are common. Many used cancer registry data and mischaracterized palliative intent for a given cancer treatment as "palliative care services." Dozens relied on the diagnosis code for "encounter for palliative care" which lacks adequate validity for use in research. Researchers, peer-reviewers, and research consumers are cautioned about these potential pitfalls that lead to meaningless or misleading research papers. Suggestions are made regarding more rigorous methods and trustworthy data sources and additional research that can lead to consensus among researchers on these issues. [ABSTRACT FROM AUTHOR]

Non-muscle invasive bladder cancer (NMIBC) is characterised by high rates of recurrence and progression, requiring substantial healthcare resources. In Latin America, the incidence of NMIBC is set to increase due to an aging population and lifestyle changes. To better understand the current challenges for NMIBC treaters and patients, a mixedmethods approach was leveraged combining secondary research with qualitative interviews from healthcare providers in Brazil, Colombia, Mexico and Argentina. Our analysis found that significant challenges persist across the region, particularly due to Bacillus Calmette-Guérin shortages, inconsistent adherence to clinical guidelines and significant socioeconomic disparities for patients accessing healthcare services. Addressing these challenges requires improved patient advocacy, strategic use of clinical trials and better resource distribution to enhance NMIBC management across Latin America. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Science is the property of Alcide De Gasperi University of Euroregional Economy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Science is the property of Alcide De Gasperi University of Euroregional Economy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article summarizes the literature on the design of a conceptual framework for secondary translanguaging classrooms. As school districts move to expand dual language programs beyond elementary schools, they are obligated to ensure that these programs are grounded in sound educational theory. Rooted in culturally sustaining perspectives, we propose a conceptual framework for dynamic dual language programming that is inclusive of translanguaging pedagogies. This conceptual framework includes key scholarship on language planning from sociocultural perspectives and offers examples of instructional approaches aligned to these perspectives. The purpose of this manuscript is to inform practice and suggest areas of potential research for secondary dual language education. [ABSTRACT FROM AUTHOR]

AbstractMarket validation is essential for assessing the feasibility of a business idea, product, or service but can involve extensive and costly primary and secondary research. Business librarians are well-positioned to support entrepreneurs and researchers but may be constrained by pricey subscriptions for business resources. While most often associated with search engine marketing, keyword research proves to be beneficial for market validation. This paper proposes integrating keyword analysis into market validation practices. It outlines the process of conducting keyword analysis and opportunities for business librarians to incorporate these strategies in their resource guides and programming. [ABSTRACT FROM AUTHOR]

AbstractThis brief report aimed to geographically describe binegativity and social distance among Hispanic Puerto Ricans, and to explore social determinants related to binegativity and social distance toward bisexual women and men. The team employed secondary research data based on a quantitative, cross-sectional study. Data from a sociodemographic questionnaire, a binegativity scale, and a social distance scale were extracted. Demographic data of a sample of 177 participants were poststratified and divided into binary categories for analysis. Results showed that half of the sample (54.2%) reported high or very high binegativity. Similarly, half of the sample (50.8%) also reported moderate or high social distance toward bisexual individuals. The study also found that participants under 30 years of age and without a religion significantly reported less binegativity. In addition, participants who identify as men, as lesbian/gay, and know a bisexual person significantly reported less social distance. The need for more research is discussed. [ABSTRACT FROM AUTHOR]

Purpose –Tourism development can provide a sustainable path through which to diversify the economy. The aim of this research is 1) to assess the current economic diversification of a potential tourism region in an emerging economy, that of the Ulytau region of Kazakhstan; 2) to detail the impediments to economic diversification through tourism development, and 3) to recommend ways to foster economic diversification. Methodology/Design/Approach – The research uses secondary data to assess the current situation of the region and in-depth interviews with tourism and economic development experts to understand the current obstacles to economic diversification. Findings – This rural region of Kazakhstan is relatively concentrated in terms of its economic diversification and investment in infrastructure such roads, airports, and telecommunication as well as marking and promotion of the natural and cultural attractions will be a path to diversify the economy through tourism development. Originality of the research – This research uses evolutionary economic geography as a useful framework through which to view how destinations change over time. The research provides a model through which other destinations, dominated by non-renewable resource extraction can pivot towards tourism as a way to diversify the economy. [ABSTRACT FROM AUTHOR]

Purpose – This study aims to evaluate the performance of the Czech spa industry within a dynamically changing external environment, specifically in the context of the COVID-19 pandemic. Considering the relationship between tourist attractiveness and fiscal policy effectiveness, the research explores the divergences existing among spa companies functioning across discrete spa resort categories within the Czech Republic. Methodology/Design/Approach – The research employs secondary data obtained from the State Statistical Office and the Business Register. The analysis entails an examination of the relationship between the level of tourist attractiveness and alterations in sales. Findings – The study reveals that spa resorts with higher levels of tourist attractiveness encountered a more pronounced decline in sales. Despite the notable allocation of public funds, the impact of subsidies on economic outcomes remained limited. Originality of the research – A contribution lies in its revelation of the adverse implications of over-reliance on tourism for the spa industry. The study highlights the imperative for diversification in resort portfolios. Moreover, the research offers valuable insights into the optimal allocation of subsidies, suggesting directions for more effective utilization and distribution in a manner that supports the industry's long-term sustainability and resilience. [ABSTRACT FROM AUTHOR]

AI is dramatically increasing service designers' capacity to deliver value. A McKinsey report (June 2023) values the potential productivity improvement of AI in customer operations at over US$400 billion annually, and the potential for marketing productivity improvement at over US$450 billion annually, thanks to efficient content creation, enhanced use of data and individual personalisation.1 To learn how AI is transforming service design, we conducted secondary research and interviews with a 40-year veteran of the tech industry, the head of design quality and collaboration for a global healthcare brand and the head of operating system customer experience for a leading luxury car brand. [ABSTRACT FROM AUTHOR]

This research was conducted to empirically test the influence of managerial ownership and managerial ability on tax avoidance, as well as the role of managerial ability in the relationship between managerial ownership and tax avoidance. This research uses secondary data in the form of company financial and annual reports. The sampling technique uses purposive sampling with the population being manufacturing companies in various industrial sectors listed on the Indonesia Stock Exchange in 2019 - 2023. This research uses regression analysis with panel data from a sample of 430 firm years. The data analysis technique for this research uses model selection tests, classical assumption tests, and hypothesis tests which are processed using STATA version 17. The research results show that managerial ownership has a negative effect on tax avoidance. Meanwhile, managerial ability has no effect on tax avoidance. Managerial ability also does not moderate the effect of managerial ownership on tax avoidance. [ABSTRACT FROM AUTHOR]

This study measured the infrared spectra of secondary minerals in the oxidation zones of three types of copper ores: dioptase, malachite, and azurite, and assigned the peak positions of OH stretching vibrations and the origins of OH combination vibrations. Dioptase contains three types of water molecules with different orientations within its ring channels, which exhibit six kinds of OH stretching vibrations in the 3000–3600 cm−1 range; the bond length range is 2.652 to 2.887 Å. Among them, the 3443 cm−1 band shows strong near-infrared activity and combines with Si–O vibrations or OH bending vibrations in the structure, resulting in five combination vibration peaks in the 4000–5000 cm−1 range. Malachite contains two inequivalent hydroxyls in its structure, leading to two OH stretching vibrations in the high-frequency region located at 3314 and 3402 cm−1, respectively. Azurite contains only one type of hydroxyl, and thus only one characteristic OH stretching vibration is present at 3424 cm−1. The OH stretching vibrations of malachite and azurite mainly combine with [CO3]2− vibrations or OH bending vibrations, leading to six and five combination peaks in the OH combination vibration region, respectively. By analyzing the combination of peak positions at 4341 cm−1 in the near-infrared spectrum, the merged OH bending vibration at 921 cm−1 in azurite was discovered. Spectroscopic research on secondary minerals can better provide a basis for ore exploration and geological remote sensing. [ABSTRACT FROM AUTHOR]

Assistive technology (AT) is a critical in providing students with visual impairments (VI) access to classroom information. However, little is known about how the fluid and diverse experiences across core-content classrooms that impact the nature of AT use among students with VI. We conducted three classroom observations of 10 secondary-age (i.e., 6th through 12th grade) students with VI in core-content classrooms (i.e., math, English, social studies, or science). Wide variations in AT use suggest that AT needs are individualized. Additionally, writing tasks, reading tasks, and independent instructional groupings were associated with the highest rates of AT usage. However, students receive little support for using their AT in classrooms. We offer implications and recommendations for research and practice aimed at increasing AT use in core-content classrooms. [ABSTRACT FROM AUTHOR]

Sarcodon mushrooms are esteemed as a rare and highly valuable resource for both culinary and medicinal purposes. Ancient medical classics have documented their beneficial effects on conditions such as indigestion, loss of appetite, and neurological disorders. Modern phytochemical research into their secondary metabolites has led to the discovery of numerous bioactive compounds with significant biological activities. Despite notable achievements in the study of the chemical composition and bioactivity of Sarcodon mushrooms, a comprehensive understanding of these findings has been lacking. This review provides an exhaustive summary of the advancements in the phytochemistry of Sarcodon mushrooms, as well as the biological and pharmacological activities of the isolated compounds and crude extracts derived from Sarcodon over the past nine decades. A total of 100 secondary metabolites isolated from these mushrooms have been classified into five major categories based on their chemical structures, which exhibit bioactivities such as anti-tumour, neurotrophic, and neuroprotective, antioxidant, anti-inflammatory, antimicrobial, and hypoglycaemic properties. The aim of this study is to establish a scientific foundation for future research in drug discovery, biotechnological development, and the exploration of functional foods involving Sarcodon mushrooms. [ABSTRACT FROM AUTHOR]

This article, through an anthropological lens inspired by Anthony Leeds’ concept of locality, examines the interplay between urban governance and autocratization in Shanghai’s gated communities during the COVID-19 pandemic. As strategic microcosms within China’s cities, these urban spaces are analysed as distinct human-geographical units to reveal the intricacies of multilevel governance within China’s authoritarian framework. Drawing on a multifaced ethnographic approach, including online and offline ethnographic research and secondary data analysis, the paper explores how gated communities act as potential enclaves for democratic practices, fostering public participation amidst strong state control. The findings highlight the pivotal role of urban fabric in shaping political dynamics, positioning gated communities as key sites for understanding deepening autocratization processes in urban China. [ABSTRACT FROM AUTHOR]

Informality has attracted significant attention in migration studies, yet a fresh look is needed given the succession of world crises over the past 15 years and the increasing use of informality to deal with them. This special issue considers informality as practices of governance that supplement, substitute, replace or operate beyond formal rules. It focuses on dissecting the governance of transit and irregular migration in the liminal space between formal policies and informal practices, and focuses on three major questions: Why and how has migration governance experienced informality’s expansion in policies and practices? What are the drivers, sites, temporalities, and implications of such an expansion? How do power relations among different stakeholders affect such governance compared to normative and institutional logics? This special issue ventures beyond existing constatations that the formal and informal are entangled. A core assertion is that informality can be a deeper structuring force, because informal interactions repeat over time, creating alternative or supplementary forms of governance beyond formal institutions. This collection of articles is original in shedding light on such governance from the perspective of world politics and political regimes, little discussed thus far in systematic ways. It is also at the forefront of theorizing on how stakeholders use mechanisms of power to govern polycentrically, that is from multiple centres related to each other but not hierarchically subordinated. This collection provides novel perspectives on socio-spatial and temporal aspects of informality’s use in such governance. Building on extensive fieldwork and data-driven secondary research, this collection covers Germany, Sweden, and Switzerland, post-socialist countries in Eastern Europe, including Belarus and Russia after the 2022 invasion of Ukraine, Turkey and Iraq in the Middle East, and Albania in the Balkans, as well as Thailand and Myanmar in Asia. [ABSTRACT FROM AUTHOR]

This paper examines the question what kind of ethics prevail in contemporary urban transport planning and what potential does an ethics of care hold for practice? Researchers have given ample attention to the need for better governance and coordination, and despite acknowledging the need to reduce reliance on private cars, little has been said by them about what ethics can or should guide planning to bring about such frameworks for caring. This area of research merits urgent work given our collective need to address the socio‐spatial, climate, and health impacts of car dependence. Taking as our focus transport planning in Victoria, Australia, we consider how an ethics of care could open new ways to redress how transport planning has perpetuated injustices in metropolitan Melbourne. We draw on secondary research to consider both the conditions that cultivated the current transport planning landscape and pathways for possible change that lie ahead. The research highlights opportunities to consider care as an ethical framework for transport planning that could amplify justice and equity claims in urban transport planning for Australian cities and that has salience for other cities elsewhere. [ABSTRACT FROM AUTHOR]

Systematic reviews should provide an unbiased summary of evidence on both benefits and harms. Authors may spin results, particularly harms, whether intentionally or unintentionally. This paper provides a framework for identifying spin and examples of and how to rectify spin. "Spin" refers to misleading reporting, interpretation, and extrapolation of findings in primary and secondary research (such as in systematic reviews). The study of spin primarily focuses on beneficial outcomes. The objectives of this research were threefold: first, to develop a framework for identifying spin associated with harms in systematic reviews of interventions; second, to apply the framework to a set of reviews, thereby pinpointing instances where spin may be present; and finally, to revise the spin examples, offering guidance on how spin can be rectified. The authors developed their framework through an iterative process that engaged an international group of researchers specializing in spin and reporting bias. The framework comprises 12 specific types of spin for harms, grouped by 7 categories across the 3 domains (reporting, interpretation, and extrapolation). The authors subsequently gathered instances of spin from a random sample of 100 systematic reviews of interventions. Of the 58 reviews that assessed harm and the 42 that did not, they found that 28 (48%) and 6 (14%), respectively, had at least 1 of the 12 types of spin for harms. Inappropriate extrapolation of the results and conclusions for harms to populations, interventions, outcomes, or settings not assessed in a review was the most common category of spin in 17 of 100 reviews. The authors revised the examples to remove spin, taking into consideration the context (for example, medical discipline, source population), findings for harms, and methodological limitations of the original reviews. They provide guidance for authors, peer reviewers, and editors in recognizing and rectifying or (preferably) avoiding spin, ultimately enhancing the clarity and accuracy of harms reporting in systematic review publications. [ABSTRACT FROM AUTHOR]

The private writings of two Southern Baptist women missionaries in China are analyzed to deepen our understanding of women's perspectives on their daily lives. After reviewing secondary research on married and single women's work in China, the author uses primary source examples from family letters and diaries to illustrate differences in responsibilities and opportunities for single and married women, and how motherhood changed their relationship to their work even further. Requirements for "homemaking", and a "civilizing mission" expected of married women, increased pressure on missionary wives. Single women, arriving in larger numbers in the early 20th century, were able to focus only on the mission work and accomplish more. The success and productivity of single women further marginalized married women, particularly those with children, who could not keep up with their single counterparts in the mission work. By exploring these two exemplars we can draw an even more nuanced picture of the many ways Baptist women missionaries negotiated their callings in light of their family status. [ABSTRACT FROM AUTHOR]

Spinal and epidural anaesthesia and analgesia are important anaesthetic techniques, familiar to all anaesthetists and applied to patients undergoing a range of surgical procedures. Although the immediate effects of a well-conducted neuraxial technique on nociceptive and sympathetic pathways are readily observable in clinical practice, the impact of such techniques on patient-centred perioperative outcomes remains an area of uncertainty and active research. The aim of this review is to present a narrative synthesis of contemporary clinical science on this topic from the most recent 5-year period and summarise the foundational scholarship upon which this research was based. We searched electronic databases for primary research, secondary research, opinion pieces, and guidelines reporting the relationship between neuraxial procedures and standardised perioperative outcomes over the period 2018–2023. Returned citation lists were examined seeking additional studies to contextualise our narrative synthesis of results. Articles were retrieved encompassing the following outcome domains: patient comfort, renal, sepsis and infection, postoperative cancer, cardiovascular, and pulmonary and mortality outcomes. Convincing evidence of the beneficial effect of epidural analgesia on patient comfort after major open thoracoabdominal surgery outcomes was identified. Recent evidence of benefit in the prevention of pulmonary complications and mortality was identified. Despite mechanistic plausibility and supportive observational evidence, there is less certain experimental evidence to support a role for neuraxial techniques impacting on other outcome domains. Evidence of positive impact of neuraxial techniques is best established for the domains of patient comfort, pulmonary complications, and mortality, particularly in the setting of major open thoracoabdominal surgery. Recent evidence does not strongly support a significant impact of neuraxial techniques on cancer, renal, infection, or cardiovascular outcomes after noncardiac surgery in most patient groups. [ABSTRACT FROM AUTHOR]

This research objectives to determine Intellectual Capital (VAIC), Growth Opportunity (GO) and Cash Holding (Cash) effect toward the Jakarta Composite Index (JCI) mediated by Company Value (PBV). The population are energy sector companies listed on the Indonesia Stock Exchange (IDX) during 2017-2023 period. This study used 74 energy companies but only 16 companies meet the sample criteria. The data used in this research are secondary data obtained from the Indonesian Stock Exchange (www.idx.co.id) and from the websites of each company. The analytical method used in this research is descriptive statistical analysis, path analysis and Sobel analysis. The results of this study indicate that the variables of intellectual capital, growth opportunity, cash holding, and company value have a positive and significant effect on the JCI. Meanwhile, the intellectual capital, growth opportunity and cash holding have a positive and significant effect on the company value. Company value as an intervening variable is able to mediate the influence of intellectual capital, growth opportunity and cash holding on JCI. [ABSTRACT FROM AUTHOR]

The effect of ionizing radiation on cells is a complex process dependent on several parameters. Cancer treatment commonly involves the use of radiotherapy. In addition to the effective killing of cancer cells, another key aspect of radiotherapy is the protection of healthy cells. An interesting position is occupied by heavy ion radiation in the field of radiotherapy due to its high relative biological effectiveness, making it an effective method of treatment. The high biological efficiency of heavy ion radiation can also pose a danger to healthy cells. The extent of cell death induced by heavy ion radiation in cells was investigated using statistical learning methods in this study. The objective was to predict the healthy cell survival rate based on the physical parameters of the available ionizing radiation. This paper is based on secondary research utilizing the PIDE database. Throughout this study, a local regression and a random forest model were generated. Their predictions were compared to the results of a linear-quadratic model commonly utilized in the field of ionizing radiation using various metrics. The relationship between dose and cell survival rate was examined using the linear-quadratic (LQM) model and local regression (LocReg). An R2 value of 88.43% was achieved for LQM and 89.86% for LocReg. Upon incorporating linear energy transfer, the random forest model attained an R2 value of 96.85%. In terms of RMSE, the linear-quadratic model yielded 9.5910−2, the local regression 9.2110−2, and the random forest 1.96 × 10−2 (lower values indicate better performance). All of these methods were also applied to a log-transformed dataset to decrease the right skewedness of the distribution of the datapoints. This significantly reduced the estimates made with LQM and LocReg (28% decrease in the case of R2), while the random forest retained nearly the same level of estimation as the untransformed data. In conclusion, it can be inferred that dose alone provides a somewhat satisfactory explanatory power for cell survival rate, but the inclusion of linear energy transfer can significantly enhance prediction accuracy in terms of variance and explanatory power. [ABSTRACT FROM AUTHOR]

As online learning has become an inevitable trend in the post-peak era of the COVID-19 pandemic, distributed pair programming (DPP) is gaining momentum in both education and industry. DDP serves as a collaborative programming approach and also benefits the development of computational thinking, a fundamental skill in today's world. This study conducted a systematic review of studies on DPP published after 2010 to understand the themes and factors that impact the team effectiveness of DPP and thus inform future research and practices on how to better leverage this approach for teaching and learning. The results showed that individual characteristics attracted major investigations in the selected 23 studies, including prior programming experience, actual skill, perceived skill, gender, personality, time management, confidence, and self-esteem, with pair compatibility identified as a critical team design factor that significantly affects programmers' satisfaction. Although the feel-good factor in the team process was investigated, no significant impact was found. Under the team environment theme, we compared different opinions on the orientation (e.g., scripted roles) and the use of technology (e.g., integrated development environment tools). Future research should investigate how task structure influences team effectiveness of DPP and relates to computational thinking education. Additionally, because most studies were conducted in higher education contexts, more research in primary and secondary educational contexts is also needed. [ABSTRACT FROM AUTHOR]

Copyright of Polityka Spoleczna is the property of Institute of Labour & Social / Instytut Pracy i Spraw Socjalnych and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

With the rapid development of urban rail transit, the environmental vibration and secondary noise induced by metro train operation have become increasingly serious, posing stricter requirements on the vibration and secondary noise of sensitive building office (SBO) and sensitive building school (SBS). To predict and control the vibrations and secondary noise in sensitive buildings along the metro line induced by metro train operations. A prediction method for the vibration and secondary noise of sensitive buildings along the metro line during metro train operation has been proposed. The sub-model of train-track system coupled dynamics and the sub-model of track-tunnel-soil-building system dynamics are included. The influence of metro train operation on the vibration and secondary noise of SBO and SBS is studied. The influence of the distance between the metro line and the building on the vibration and secondary noise of the sensitive building is discussed, and an effective control scheme of vibration and secondary noise is proposed. Results show that the vibration frequencies of the SBS and the SBO caused by the metro train operation are concentrated at about 8Hz and 63Hz. The vibration below the second floor of SBO caused by the metro train operation exceeds the limit, and the secondary noise below the third floor of SBS exceeds the limit. The secondary noise inside the building of each floor of SBO exceeded the limit. Using secondary noise to evaluate the environmental impact of metro train operations is more stringent than relying solely on vibration assessments. secondary noise is recommended in engineering to assess the impact of metro train operation on sensitive buildings along line. Combined with vibration, secondary noise and construction requirements, SBS and SBO are recommended to be no less than 72m and 74m away from the metro line, respectively. [ABSTRACT FROM AUTHOR]

Reporting findings from action research in Secondary Vocational Schools (SVSs) in Palestine contributes to our understanding of the five criteria that underpin excellence in Work-Based Learning (WBL) This paper presents a new model for promoting WBL performance for SVSs in Palestine by focusing on five key indicators derived from previous research analysis and findings for the researcher of this paper, the European Foundation for Quality Management (EFQM) and the Quality, Cost and Delivery (QCD) model. This paper addresses the question of how to promote WBL in SVSs in Palestine? In-depth interviews with 52 school personnel and 85 students from three SVSs in Palestine were conducted. A five-question descriptive questionnaire was administered to all respondents to assess the five key performance indicators to identify performance gaps. Analysis of the responses provides an understanding of the causes of the gaps and helps provide explanations to develop an action plan to improve performance. [ABSTRACT FROM AUTHOR]

Background: Mongolia introduced liver transplantation 10 years ago, becoming the 46th country globally to successfully perform this procedure. However, the cost of liver transplantation treatment remains expensive in Mongolia, a lower-middle-income country. Thus, the need to calculate the cost of liver transplants, a highly-valued treatment, forms the basis for this study. Methods: This study employed a retrospective research design with secondary data. The primary dataset comprised 143 cases of liver transplantation performed at the First Central Hospital of Mongolia between 2011 and 2021. Results: The average cost of a liver transplant in Mongolia is $39,589 ± 10,308, with 79.6% being direct costs and 20.4% indirect costs. Of the direct costs, 71% were attributed to drugs, medical equipment, and supplies, while 8.6% accounted for salaries. In terms of the Model of End-Stage Liver Disease (MELD) scores, treatment costs were $39,205 ± 10,786 for patients with MELD ≤ 14 points, $40,296 ± 1,517 for patients with MELD 15–20 points, $39,352 ± 8,718 for patients with MELD 21–27 points, and $39,812 ± 9,954 for patients with MELD ≤ 28 points, with no statistically significant difference (P = 0.953). However, when calculated according to the Child-Turcotte-Pugh (CTP) score classification, treatment cost for CTP-A patients was $35,970 ± 6,879, for CTP-B patients $41,951 ± 12,195, and for CTP-C patients $37,396 ± 6,701, which was statistically significant (Р=0.015). Conclusion: The average cost of liver transplantation treatment in Mongolia was $39,589. Despite medical facilities' capacity to treat up to 50 patients annually, the waiting list exceeds 300 individuals, highlighting significant unmet healthcare needs. [ABSTRACT FROM AUTHOR]

Using secondary research from the political, education, and employment fields, this paper aims to demonstrate the consequences of confused and overlapping conceptualizations of the Roma in Hungary as an ethnic group, a racialized minority, a national minority, and a socially disadvantaged group. The resulting cacophony of operationalizing schemes blurs clarity and constrains efficient measures for inclusion policies. In social sciences and law, the purpose of classification is to help us understand the internal logic of concepts. Thus, classification has significant consequences, as it can imperil policy goals. Through examining the case of the Hungarian Roma, the article demonstrates how the confused conceptualization of ethnicity, race, and nationality and ill-applied methods of operationalization have vastly detrimental consequences. In addition, it is argued that many concerns regarding ethnic data processing that policy actors voice are legally unfounded, and pre-existing data protection regimes allow the processing of ethno-racial data. [ABSTRACT FROM AUTHOR]

Introduction: The outpatient parenteral antibiotic therapy (OPAT) program of Vancouver General Hospital (VGH) was supervised by emergency physicians (EPs) until 2017 when infectious disease (ID) physicians began assisting in management. We designed a retrospective study to determine whether ID involvement led to improved outcomes. Methods: This study analyzes the impact of ID involvement by comparing the mean days patients spent on OPAT with ID involvement versus EPs alone through a retrospective chart review. Secondary research objectives were to compare patient care decisions, e.g., antibiotic choice, tests ordered, and final diagnosis. Results: There was no difference between the mean number of days on OPAT between physician types. Compared to historic patterns, patients seen in OPAT after increased ID consultation spent an average of 0.5 fewer days in the program. However, when grouped by the first day of ID assessment, the average total days in OPAT was closely aligned with the day of first ID assessment, implying that ID frequently discharged patients close to initial assessment. Patients seen by ID were less likely to return within one month of discharge compared to those not seen by ID. Secondary findings include ID physicians prescribing a greater range of antibiotics, providing more varied final diagnoses, prescribing antibiotics less frequently, as well as ordering more cultures, diagnostic imaging and specialist consults. Discussion: The findings of this study support the hypothesis that ID involvement in OPAT programs leads to changes in care that may have beneficial outcomes for patients and the healthcare system. [ABSTRACT FROM AUTHOR]

Informed consent is an essential part of conducting human subjects research; but its utility is dependent on participants actually reading the consent forms provided. This research conducted secondary analysis of data (N = 1,283) to assess how long participants spent on the consent forms. Participants spent an average of 35.4 seconds on consent documents: not a nonsignficant amount of time (i.e., different from 0 seconds), but insufficient to read or even skim consent forms. Women spent slightly less time on consent forms. Neither the length nor readability of a consent form predicted time spent reading, and neither readability nor gender moderated the relationship between word count and time spent reading. Results suggest participants in communication studies do not spend enough time on a consent document to be able to read it, and therefore modern practices of informed consent do not ensure informed participation in research. [ABSTRACT FROM AUTHOR]

This is the first study on the tradition and cultural heritage of the rakija market based on consumer behavior analysis. The primary objective is to investigate the impact of cultural tradition on consumer behavior regarding the purchase of rakija, the national alcoholic beverage of Serbia. The secondary objective of this research is to measure the magnitude to which the marketing program of distilleries influences consumers' purchases of rakija. The research data were collected in Serbia from December 2023 to March 2024 utilizing a survey approach. Electronic data collection was carried out through an online questionnaire. The study sample comprised 608 valid respondents (n=608) who were chosen randomly. Traditional cultural heritage affects the purchase of rakija; however, the UNESCO recognition of šljivovica as part of its intangible heritage list does not. Moreover, the marketing program of distilleries affects the purchase of rakija. However, the effect sizes of these phenomena are insignificant. [ABSTRACT FROM AUTHOR]

Career education in secondary schools plays a pivotal role in supporting students as they navigate the complex decision-making process involved in the transition to higher education. However, the evidence base regarding the effectiveness of career education is limited and fragmented, with a distinct lack of clarity regarding the underlying mechanisms. This study aimed to identify the best practices and underlying mechanisms of career education within Dutch secondary education. Based on focus group interviews with stakeholders with diverse interests and positions (N = 25), we identified five categories of best practice activities alongside a framework consisting of ten mediators, eight moderators, a meta-moderator, and four contextual factors. This framework, while reinforcing some previous identified mechanisms, brings new elements into focus, distinguishing additional mechanisms and their categorisation as mediators, moderators, and contextual factors. These findings may serve as a foundational framework for future research and can support schools in enhancing their career education curricula. It is crucial that career education activities align with the students' current capacities and potential for growth, ensuring that these programs are responsive to students' developmental stages and their zone of proximal development. [ABSTRACT FROM AUTHOR]

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During the second half of the 2012–13 theatre season, we mapped all then-existing educational theatre practices in Hungary against a standardized set of criteria. We contacted a total of 298 institutions and observed 118 programmes in person. We aimed to map the complete picture, so we involved every programme that fitted our low-threshold criteria and responded to our inquiry. Presumably, we covered the entire Hungarian educational theatre sphere. For each programme, we collected data from six sources: children or youth participating in the programmes; teachers accompanying the participants; organizational contact persons; creators/performers of the programmes; observing of the programmes by independent observers; and secondary research on the internet. In 2023, we repeated part of this data collection. In this article, we present the methodology used for the mapping in detail since we believe it can serve as a model for similar mappings in other countries. [ABSTRACT FROM AUTHOR]

During the second half of the 2012–13 theatre season, we mapped all then-existing educational theatre practices in Hungary against a standardized set of criteria. We contacted a total of 298 institutions and observed 118 programmes in person. For each programme, we collected data from six sources: children or youth participating in the programmes; teachers accompanying the participants; organizational contact persons; creators/performers of the programmes; observing of the programmes by independent observers; and secondary research on the internet. In this article, we present an interpretative qualitative analysis of the findings. Covered areas include whether a programme could alter prejudice and bias, whether post-show workshops can find solutions to issues raised by theatre performances and whether participant children and youth can link performances and programmes to current Hungarian events. [ABSTRACT FROM AUTHOR]

During the second half of the 2012–13 theatre season, we mapped all then-existing educational theatre practices in Hungary against a standardized set of criteria. We contacted a total of 298 institutions and observed 118 programmes in person. For each programme, we collected data from six sources: children or youth participating in the programmes; teachers accompanying the participants; organizational contact persons; creators/performers of the programmes; observing of the programmes by independent observers; and secondary research on the internet. In this article, we present the descriptive statistical analysis of the findings. Areas covered include the role and significance of educational theatre; programme financing; participants and programme admission; number and length of sessions; programme venues; strategies and interactivity; aims and objectives; impacts; opinions; and relevance. [ABSTRACT FROM AUTHOR]

Secondary research is burgeoning in the field of Applied Linguistics, taking the form of both narrative literature review and especially more systematic research synthesis. Clearly purposed and methodologically sound secondary research contributes to the field because it provides useful and reliable summaries in a given domain, facilitates research dialogues between sub-fields, and reduces redundancies in the published literature. It is important to understand that secondary research is an umbrella term that includes numerous types of literature review. In this commentary, we present a typology of 13 types of well-established and emergent types of secondary research in Applied Linguistics. Employing a four-dimensional analytical framework, focus, review process, structure, and representation of text of the 13 types of secondary research are discussed, supported by examples. This article ends with recommendations for conducting secondary research and calls for further inquiry into field-specific methodology of secondary research. [ABSTRACT FROM AUTHOR]

This paper gives thought to the exploitation of Niger's natural resources by France, the European Union (EU), and the United States (US), among other countries. The objective of this paper is to deconstruct the exploitation of Niger's uranium, gold, and coal, among other natural resources, and the surge in terrorism. This paper adopts qualitative secondary research as its methodology and resource curse theory as its theoretical framework. The gap that the paper bridges is that most research about the exploitation of Niger's natural resources and the rise in terrorism ignores the involvement of France among other Western countries. Findings that develop from this paper reveal that France has exploited Niger's natural resources since colonisation. Similarly, the EU and the US, among other countries, have been accomplices in the exploitation of Niger's natural resources. Additionally, Western countries, namely France, the EU, and the US, including Britain and Russia, have been involved in supporting administrations or terrorists that advance their interests in Niger, among other issues. Further results show that successive administrations in Niger and those that took control through the coup in July 2023 enjoy the support of the major global powers. [ABSTRACT FROM AUTHOR]

Simple Summary: For decades, numerous hypotheses have been suggested to explain why nest characteristics should be associated with reproductive success. However, quantitative intraspecific studies of associations between variations in nest architecture and breeding success remain rare, and they are most often conducted on model species of which nests can be easily monitored with artificial nest-boxes. Here, we review the published literature dealing with the reproductive consequences of nest design in the best-studied secondary-cavity-nesting bird species. We show that research protocols and findings are often poorly replicated across repeat studies. We discuss why many field studies report weak associations between nest architecture characteristics and breeding success and propose suggestions for future research directions. More than 40 hypotheses predict associations between features of nest architecture and at least one measure of reproductive success. However, quantitative studies of reproductive consequences of nest characteristics remain scarce. In addition, most studies were conducted on model species of which nests can be easily monitored with artificial nest-boxes. Here, we review the replicability of research protocols and findings in model species, with many repeat studies focusing mainly on nest-size components, animal-derived nest material, or fresh greenery in model species of secondary hole-nesting birds: Blue Tits (Cyanistes caeruleus), Great Tits (Parus major), Tree Swallows (Tachycineta bicolor), and Starlings (Sturnus spp.). The studies looked for correlations between nest traits and aspects of breeding performance that can be easily quantified in the field, such as clutch size, brood size at hatching or fledging, the percentage of eggs that hatch or fledge, or nestling characteristics assumed to reflect qualities associated with survival probabilities (e.g., morphometry, body condition, blood profiles). We discuss the consequences of poor replicability of research methodologies and provide explanations for why many of these studies reported poor associations between nest design and breeding success at different spatiotemporal scales. We also make suggestions for future research. [ABSTRACT FROM AUTHOR]

The article uncovers the connection between Article II(e) of the Genocide Convention and the Greek Civil War (1946–49). Through archival research and secondary sources, it reconstructs the Greek legal arguments that framed the transfer of children conducted by the communist guerrillas in Northern Greece as an act of genocide and led to the inclusion of this action in the legal definition of genocide. By analyzing the arguments of the Greek government, it presents a new interpretation of Article II(e) of the Convention. It is contended that the historical antecedent of the provision supports a biopolitical understanding of the genocidal act in question. The article concludes with a more general discussion of the continuing importance of Article II(e). [ABSTRACT FROM AUTHOR]