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We present the first empirical constraints on the turbulent velocity field of the diffuse circumgalactic medium around four luminous QSOs at $z\!\approx\!0.5$--1.1. Spatially extended nebulae of $\approx\!50$--100 physical kpc in diameter centered on the QSOs are revealed in [OII]$\lambda\lambda\,3727,3729$ and/or [OIII]$\lambda\,5008$ emission lines in integral field spectroscopic observations obtained using MUSE on the VLT. We measure the second- and third-order velocity structure functions (VSFs) over a range of scales, from $\lesssim\!5$ kpc to $\approx\!20$--50 kpc, to quantify the turbulent energy transfer between different scales in these nebulae. While no constraints on the energy injection and dissipation scales can be obtained from the current data, we show that robust constraints on the power-law slope of the VSFs can be determined after accounting for the effects of atmospheric seeing, spatial smoothing, and large-scale bulk flows. Out of the four QSO nebulae studied, one exhibits VSFs in spectacular agreement with the Kolmogorov law, expected for isotropic, homogeneous, and incompressible turbulent flows. The other three fields exhibit a shallower decline in the VSFs from large to small scales. However, with a limited dynamic range in the spatial scales in seeing-limited data, no constraints can be obtained for the VSF slopes of these three nebulae. For the QSO nebula consistent with the Kolmogorov law, we determine a turbulence energy cascade rate of $\approx\!0.2$ cm$^{2}$ s$^{-3}$. We discuss the implication of the observed VSFs in the context of QSO feeding and feedback in the circumgalactic medium., Comment: 20 pages, 6 figures in main text + 9 figures in appendix, 4 tables; accepted by MNRAS

This clinical challenge discusses a case in which a patient was referred for aortic valve repair or replacement due to severe aortic regurgitation from infective endocarditis. In addition to discovering a previously unknown tricuspid valve vegetation, the intraoperative echocardiographic evaluation was instrumental in revealing an undiagnosed Gerbode defect. The flow through this Gerbode defect was previously mistaken for tricuspid regurgitation, and the patient was misdiagnosed as exhibiting severe pulmonary hypertension. This case highlights the importance of reviewing preoperative echocardiographic imaging, as well as diligence in completing a thorough intraoperative transesophageal echocardiographic exam prior to cardiopulmonary bypass. In addition, while flow typically occurs in Gerbode defects during systole, this case demonstrates that flow can also occur during diastole, which was most likely due to the severe aortic regurgitation. Fortunately, the patient was able to undergo successful treatment for the unexpected sequalae of the infective endocarditis, including repair of the Gerbode defect, tricuspid valve repair, and aortic valve and root replacement. Importantly, the incorrect diagnosis of severe pulmonary hypertension was removed.

We report optical integral-field spectroscopy in the field of one of the most luminous quasars in the $z < 1$ Universe, PKS0454-22, with the Multi-Unit Spectroscopic Explorer. These data enable the discovery of three large ionized nebulae emitting in [O II], H$\beta$, and [O III] with projected areas of $1720, \ 1520,$ and $130 \ \mathrm{pkpc}^2$, which we refer to as N1, N2, and N3, respectively. N1 spatially and kinematically surrounds the quasar host and five nearby galaxies. The morphology and kinematics of N1 are most consistent with stripped interstellar medium resulting from ongoing interactions. Its ionization properties can be explained by quasar photoionization. N2 spatially and kinematically surrounds two galaxies which are at projected distances of $d \approx 90 \ \mathrm{pkpc}$ and line-of-sight velocities of $\Delta v \approx +1410\ \mathrm{km\ s^{-1}}$ from the quasar. The morphology and kinematics of N2 are also consistent with stripped interstellar medium. However, its ionization state requires additional ionization sources beyond the quasar, likely from fast shocks as it moves through the hot halo associated with a galaxy over-density around the quasar. N3 is not coincident with any galaxies with secure redshifts, and may arise from a cool gas structure in the intragroup medium or a dwarf galaxy. These large ionized nebulae demonstrate that interactions can produce cool gas structures on halo scales, while also possibly facilitating quasar fueling. The growing availability of wide-area integral field spectroscopic data will continue to reveal the morphologies, kinematics, and conditions of the gas flows, which may fuel galaxy and black hole growth., Comment: Accepted to MNRAS; main text 16 pages, 7 figures and 2 tables; appendix 2 pages and 2 figures

Ni, Y. Q., et al., Type Ia supernovae are thermonuclear explosions of white dwarf stars. They play a central role in the chemical evolution of the Universe and are an important measure of cosmological distances. However, outstanding questions remain about their origins. Despite extensive efforts to obtain natal information from their earliest signals, observations have thus far failed to identify how the majority of them explode. Here, we present infant-phase detections of SN 2018aoz from a very low brightness of −10.5 AB absolute magnitude, revealing a hitherto unseen plateau in the B band that results in a rapid redward colour evolution between 1.0 and 12.4 hours after the estimated epoch of first light. The missing B-band flux is best explained by line-blanket absorption from Fe-peak elements in the outer 1% of the ejected mass. The observed B − V colour evolution of the supernova also matches the prediction from an over-density of Fe-peak elements in the same outer 1% of the ejected mass, whereas bluer colours are expected from a purely monotonic distribution of Fe-peak elements. The presence of excess nucleosynthetic material in the extreme outer layers of the ejecta points to enhanced surface nuclear burning or extended subsonic mixing processes in some normal type Ia SN explosions., D.-S.M., M.R.D. and C.D.M. are supported by Discovery Grants from the Natural Sciences and Engineering Research Council of Canada. D.-S.M. was supported in part by a Leading Edge Fund from the Canadian Foundation for Innovation (project no. 30951). M.R.D. was supported in part by the Canada Research Chairs Program, the Canadian Institute for Advanced Research (CIFAR) and the Dunlap Institute at the University of Toronto. D.J.S. acknowledges support by NSF grant nos. AST-1821987, 1821967 and 1908972 and from the Heising–Simons Foundation under grant no. 2020-1864. S.G.-G. acknowledges support by FCT under project CRISP PTDC/FIS-AST-31546 and project UIDB/00099/2020. H.S.P. was supported in part by a National Research Foundation (NRF) of Korea grant funded by the Korean government (MSIT, Ministry of Science and ICT; no. NRF-2019R1F1A1058228). P.J.B. acknowledges support from the Swift GI program 80NSSC19K0316. S.V., Y.D. and K.A.B. acknowledge support by NSF grant nos. AST-1813176 and AST-2008108. C.M. acknowledges support by NSF grant AST-1313484. I.A. is a CIFAR Azrieli Global Scholar in the Gravity and the Extreme Universe Program and acknowledges support from that program, from the Israel Science Foundation (grant nos. 2108/18 and 2752/19), from the United States – Israel Binational Science Foundation (BSF) and from an Israeli Council for Higher Education Alon Fellowship. R.L.B. acknowledges support by NASA through Hubble Fellowship grant no. 51386.01 awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., for NASA under contract no. NAS 5-26555. A.G.-Y. acknowledges support from the European Union via ERC grant no. 725161, the ISF GW Excellence Center, an IMOS space infrastructure grant and BSF/Transformative and GIF grants, as well as from the Benoziyo Endowment Fund for the Advancement of Science, the Deloro Institute for Advanced Research in Space and Optics, the Veronika A. Rabl Physics Discretionary Fund, P. and T. Gardner, the Yeda-Sela Center for Basic Research and a WIS-CIT joint research grant. A.G.-Y. is the recipient of the Helen and Martin Kimmel Award for Innovative Investigation. L.G. acknowledges financial support from the Spanish Ministerio de Ciencia e Innovación (MCIN), the Agencia Estatal de Investigación (AEI) 10.13039/501100011033, the European Social Fund (ESF) ‘Investing in your future’ under the 2019 Ramón y Cajal program RYC2019-027683-I and the PID2020-115253GA-I00 HOSTFLOWS project, as well as from the Centro Superior de Investigaciones Científicas (CSIC) under the PIE project 20215AT016. G.P. acknowledges support from the Millennium Science Initiative through grant no. IC120009. J.A. is supported by the Stavros Niarchos Foundation (SNF) and the Hellenic Foundation for Research and Innovation (HFRI) under the 2nd Call of ‘Science and Society’ Action ‘Always strive for excellence – Theodoros Papazoglou’ (project no. 01431).

Although mesenchymal stem/stromal cells (MSCs) are being explored in numerous clinical trials as proangiogenic and proregenerative agents, the influence of tissue origin on the therapeutic qualities of these cells is poorly understood. Complicating the functional comparison of different types of MSCs are the confounding effects of donor age, genetic background, and health status of the donor. Leveraging a clinical setting where MSCs can be simultaneously isolated from discarded but healthy bone and thymus tissues from the same neonatal patients, thereby controlling for these confounding factors, we performed an in vitro and in vivo paired comparison of these cells. We found that both neonatal thymus (nt)MSCs and neonatal bone (nb)MSCs expressed different pericytic surface marker profiles. Further, ntMSCs were more potent in promoting angiogenesis in vitro and in vivo and they were also more motile and efficient at invading ECM in vitro. These functional differences were in part mediated by an increased ntMSC expression of SLIT3, a factor known to activate endothelial cells. Further, we discovered that SLIT3 stimulated MSC motility and fibrin gel invasion via ROBO1 in an autocrine fashion. Consistent with our findings in human MSCs, we found that SLIT3 and ROBO1 were expressed in the perivascular cells of the neonatal murine thymus gland and that global SLIT3 or ROBO1 deficiency resulted in decreased neonatal murine thymus gland vascular density. In conclusion, ntMSCs possess increased proangiogenic and invasive behaviors, which are in part mediated by the paracrine and autocrine effects of SLIT3., Comparison of mesenchymal stem/stromal cells (MSCs) from the human neonatal thymus and bone revealed that the axon guidance molecule SLIT3 is important for MSC proangiogenic effects. Not only is SLIT3 an endothelial cell stimulatory factor, but it also promotes MSC migration and invasion in an autocrine fashion via the ROBO1 receptor. Deficiency of either SLIT3 or ROBO1 can decrease the vascularization of the neonatal thymus.

Lyman$-\alpha$ (Ly$\alpha$) emission lines are typically found to be redshifted with respect to the systemic redshifts of galaxies, likely due to resonant scattering of Ly$\alpha$ photons. Here we measure the average velocity offset for a sample of 96 $z\approx3.3$ Ly$\alpha$ emitters (LAEs) with a median Ly$\alpha$ flux (luminosity) of $\approx 10^{-17}~\rm erg~cm^{-2}~s^{-1}$ ($\approx10^{42}~\rm erg~s^{-1}$) and a median star formation rate (SFR) of $\approx1.3 \rm M_{\odot} yr^{-1}$ (not corrected for possible dust extinction), detected by the Multi-Unit Spectroscopic Explorer as part of our MUSEQuBES circumgalactic medium (CGM) survey. By postulating that the stacked CGM absorption profiles of these LAEs, probed by 8 background quasars, must be centered on the systemic redshift, we measure an average velocity offset, V$_{\rm offset} = 171 \pm 8$ $\rm km s^{-1}$, between the Ly$\alpha$ emission peak and the systemic redshift. The observed V$_{\rm offset}$ is lower by factors of $\approx1.4$ and $\approx2.6$ compared to the velocity offsets measured for narrow-band selected LAEs and Lyman break galaxies, respectively, which probe galaxies with higher masses and SFRs. Consistent with earlier studies based on direct measurements for individual objects, we find that the V$_{\rm offset}$ is correlated with the full width at half-maximum of the red peak of the Ly$\alpha$ line, and anti-correlated with the rest-frame equivalent width. Moreover, we find that $V_{\rm offset}$ is correlated with SFR with a sub-linear scaling relation, V$_{\rm offset}\propto \rm SFR^{0.16\pm0.03}$. Adopting the mass scaling for main sequence galaxies, such a relation suggests that V$_{\rm offset}$ scales with the circular velocity of the dark matter halos hosting the LAEs., Comment: Published on 15 May, 2020 along with an erratum (Ref: MNRAS 498, 4424, 2020, doi:10.1093/mnras/staa2668), since Fig. 2 has not been updated in the published version. There are other typos in the published version, introduced by the typesetter, which cannot be revised in the erratum. We feel that the astrp-ph version is more accurate than the published one

This paper presents a systematic study of the photoionization and thermodynamic properties of the cool circumgalactic medium (CGM) as traced by rest-frame ultraviolet absorption lines around 26 galaxies at redshift $z\lesssim1$. The study utilizes both high-quality far-ultraviolet and optical spectra of background QSOs and deep galaxy redshift surveys to characterize the gas density, temperature, and pressure of individual absorbing components and to resolve their internal non-thermal motions. The derived gas density spans more than three decades, from $\log (n_{\rm H}/{\rm cm^{-3}}) \approx -4$ to $-1$, while the temperature of the gas is confined in a narrow range of $\log (T/{\rm K})\approx 4.3\pm 0.3$. In addition, a weak anti-correlation between gas density and temperature is observed, consistent with the expectation of the gas being in photoionization equilibrium. Furthermore, decomposing the observed line widths into thermal and non-thermal contributions reveals that more than 30% of the components at $z\lesssim 1$ exhibit line widths driven by non-thermal motions, in comparison to $, Comment: 16 pages, 4 figures, 1 table, accepted for publication in MNRAS

Intraoperative transesophageal echocardiography currently is used routinely for many cardiothoracic surgical procedures. Although it is often used for intraoperative cardiac monitoring and to confirm preoperative echocardiographic findings, it may sometimes result in the discovery of unexpected pathology. In this e-challenge, a patient was found to have a mitral valve abnormality that was not previously detected on the preoperative transthoracic echocardiogram. The mitral valve anomaly subsequently was evaluated to characterize the anatomy, interrogate the valve, and provide a diagnosis.

In the coming decade, a new generation of massively multiplexed spectroscopic surveys, such as the Prime Focus Spectrograph Galaxy Evolution Survey (PFS), Wide Area Vista Extragalactic Survey-Deep (WAVES), and Multi-Object Optical and Near-infrared Spectrograph (MOONS) for the Very Large Telescope, will probe galaxies in the distant universe in vastly greater numbers than was previously possible. In this work, we generate mock catalogs for each of these three planned surveys to help quantify and optimize their scientific output. To assign photometry into the UniverseMachine empirical model, we develop the Calibrating Light: Illuminating Mocks By Empirical Relations procedure using Ultra Deep Survey with the Visible and Infrared Survey Telescope for Astronomy (UltraVISTA) photometry. Using the published empirical selection functions for each aforementioned survey, we quantify the mass completeness of each survey. We compare different targeting strategies by varying the area and targeting completeness, and quantify how these survey parameters affect the uncertainty of the two-point correlation function. We demonstrate that the PFS and MOONS measurements will be primarily dominated by cosmic variance, not shot noise, motivating the need for increasingly large survey areas. On the other hand, the WAVES survey, which covers a much larger area, will strike a good balance between cosmic variance and shot noise. For a fixed number of targets, a 5% increased survey area (and ∼5% decreased completeness) would decrease the uncertainty of the correlation function at intermediate scales by 0.15%, 1.2%, and 1.1% for our WAVES, PFS, and MOONS samples, respectively. Meanwhile, for a fixed survey area, 5% increased targeting completeness improves the same constraints by 0.7%, 0.25%, and 0.1%. All of the utilities used to construct our mock catalogs and many of the catalogs themselves are publicly available.

We present an analysis of the galaxy environment and physical properties of a partial Lyman limit system at z = 0.83718 with HI and metal line components closely separated in redshift space ($|\Delta v| \approx 400$ km/s) towards the background quasar HE1003+0149. The HST/COS far-ultraviolet spectrum provides coverage of lines of oxygen ions from OI to OV. Comparison of observed spectral lines with synthetic profiles generated from Bayesian ionization modeling reveals the presence of two distinct gas phases in the absorbing medium. The low-ionization phase of the absorber has sub-solar metallicities (1/10-th solar) with indications of [C/O] < 0 in each of the components. The OIV and OV trace a more diffuse higher-ionization medium with predicted HI column densities that are $\approx 2$ dex lower. The quasar field observed with VLT/MUSE reveals three dwarf galaxies with stellar masses of $M^* \sim 10^{8} - 10^{9}$ M$_\odot$, and with star formation rates of $\approx 0.5 - 1$ M$_\odot$ yr$^{-1}$, at projected separations of $\rho/R_{\mathrm{vir}} \approx 1.8 - 3.0$ from the absorber. Over a wider field with projected proper separation of $\leq 5$ Mpc and radial velocity offset of $|\Delta v| \leq 1000$ km/s from the absorber, 21 more galaxies are identified in the $VLT$/VIMOS and Magellan deep galaxy redshift surveys, with 8 of them within $1$ Mpc and $500$ km/s, consistent with the line of sight penetrating a group of galaxies. The absorber presumably traces multiple phases of cool ($T \sim 10^4$ K) photoionized intragroup medium. The inferred [C/O] < 0 hints at preferential enrichment from core-collapse supernovae, with such gas displaced from one or more of the nearby galaxies, and confined to the group medium.

(Abridged) We present a systematic investigation of physical conditions and elemental abundances in four optically thick Lyman-limit systems (LLSs) at $z=0.36-0.6$ discovered within the Cosmic Ultraviolet Baryon Survey (CUBS). CUBS LLSs exhibit multi-component kinematic structure and a complex mix of multiphase gas, with associated metal transitions from multiple ionization states that span several hundred km/s in line-of-sight velocity. Specifically, higher column density components (log N(HI)>16) in all four absorbers comprise dynamically cool gas with $\langle T \rangle =(2\pm1) \times10^4\,$K and modest non-thermal broadening of $5\pm3\,$ km/s. The high quality of the QSO absorption spectra allows us to infer the physical conditions of the gas, using a detailed ionization modeling that takes into account the resolved component structures of HI and metal transitions. The range of inferred gas densities indicates that these absorbers consist of spatially compact clouds with a median line-of-sight thickness of $160^{+140}_{-50}$ pc. While obtaining robust metallicity constraints for the low-density, highly ionized phase remains challenging due to the uncertain N(HI), we demonstrate that the cool-phase gas in LLSs has a median metallicity of $\mathrm{[\alpha/H]_{1/2}}=-0.7^{+0.1}_{-0.2}$, with a 16-84 percentile range of $\mathrm{[\alpha/H]}=(-1.3,-0.1)$. Furthermore, the wide range of inferred elemental abundance ratios ($\mathrm{[C/\alpha]}$, $\mathrm{[N/\alpha]}$, and $\mathrm{[Fe/\alpha]}$) indicate a diversity of chemical enrichment histories. Combining the absorption data with deep galaxy survey data characterizing the galaxy environment of these absorbers, we discuss the physical connection between star-forming regions in galaxies and diffuse gas associated with optically thick absorption systems in the $z, Comment: Accepted for publication in MNRAS after a minor revision. 18 pages, 11 figures, and a nine-page Appendix with four additional figures

We present the first characterization of the circumgalactic medium of Ly α emitters (LAEs), using a sample of 96 z ≈ 3.3 LAEs detected with the VLT/MUSE in fields centred on eight bright background quasars. The LAEs have low Ly α luminosities ($\sim 10^{42}\, \text{erg}\, \text{s}^{-1}$) and star formation rates (SFRs) $\sim 1~\text{M}_\odot \, \text{yr}^{-1}$, which for main-sequence galaxies correspond to stellar masses of only $\sim 10^{8.6}\, \text{M}_\odot$. The median transverse distance between the LAEs and the quasar sightlines is 165 proper kpc (pkpc). We stacked the high-resolution quasar spectra and measured significant excess H i and C iv absorption near the LAEs out to 500 $\text{km}\, \text{s}^{-1}$ and at least ≈250 pkpc (corresponding to ≈7 virial radii). At $\lesssim 30~\text{km}\, \text{s}^{-1}$ from the galaxies, the median H i and C iv optical depths are enhanced by an order of magnitude. The absorption is significantly stronger around the ≈1/3 of our LAEs that are part of ‘groups’, which we attribute to the large-scale structures in which they are embedded. We do not detect any strong dependence of either the H i or C iv absorption on transverse distance (over the range ≈50–250 pkpc), redshift, or the properties of the Ly α emission line (luminosity, full width at half-maximum, or equivalent width). However, for H i, but not C iv, the absorption at $\lesssim 100\, \text{km}\, \text{s}^{-1}$ from the LAE does increase with the SFR. This suggests that LAEs surrounded by more H i tend to have higher SFRs.

Outflows from super-massive black holes (SMBHs) play an important role in the co-evolution of themselves, their host galaxies, and the larger scale environments. Such outflows are often characterized by emission and absorption lines in various bands and in a wide velocity range blueshifted from the systematic redshift of the host quasar. In this paper, we report a strong broad line region (BLR) outflow from the z~4.7 quasar BR 1202-0725 based on the high-resolution optical spectrum taken with the Magellan Inamori Kyocera Echelle (MIKE) spectrograph installed on the 6.5m Magellan/Clay telescope, obtained from the `Probing the He II re-Ionization ERa via Absorbing C IV Historical Yield' (HIERACHY) project. This rest-frame ultraviolet (UV) spectrum is characterized by a few significantly blueshifted broad emission lines from high ions; the most significant one is the C IV line at a velocity of -6500 km/s relative to the H{\alpha} emission line, which is among the highest velocity BLR outflows in observed quasars at z > 4. The measured properties of UV emission lines from different ions, except for O I and Ly{\alpha}, also follow a clear trend that higher ions tend to be broader and outflow at higher average velocities. There are multiple C IV and Si IV absorbing components identified on the blue wings of the corresponding emission lines, which may be produced by either the outflow or the intervening absorbers., Comment: Accepted for publication in the MNRAS. 15 pages, 7 figures, 3 tables

We present a detailed study of two partial Lyman limit systems (pLLSs) of neutral hydrogen column density $N_\mathrm{H\,I}\approx(1-3)\times10^{16}\,\mathrm{cm}^{-2}$ discovered at $z=0.5$ in the Cosmic Ultraviolet Baryon Survey (CUBS). Available far-ultraviolet spectra from the Hubble Space Telescope Cosmic Origins Spectrograph and optical echelle spectra from MIKE on the Magellan Telescopes enable a comprehensive ionization analysis of diffuse circumgalactic gas based on resolved kinematics and abundance ratios of atomic species spanning five different ionization stages. These data provide unambiguous evidence of kinematically aligned multi-phase gas that masquerades as a single-phase structure and can only be resolved by simultaneous accounting of the full range of observed ionic species. Both systems are resolved into multiple components with inferred $\alpha$-element abundance varying from $[\alpha/\text{H}]\approx\!{-0.8}$ to near solar and densities spanning over two decades from $\log n_\mathrm{H}\mathrm{cm}^{-3}\approx\!-2.2$ to $, Comment: Accepted for publication in MNRAS, 27 pages, 21 figures

We present a survey of MgII absorbing gas in the vicinity of 380 random galaxies, using 156 background quasi-stellar objects(QSOs) as absorption-line probes. The sample comprises 211 isolated (73 quiescent and 138 star-forming galaxies) and 43 non-isolated galaxies with sensitive constraints for both MgII absorption and Ha emission. The projected distances span a range from d=9 to 497 kpc, redshifts of the galaxies range from z=0.10 to 0.48, and rest-frame absolute B-band magnitudes range from $M_{\rm B}=-16.7$ to $-22.8$. Our analysis shows that the rest-frame equivalent width of MgII, $W_r$(2796), depends on halo radius($R_h$), $B$-band luminosity($L_{\rm B}$) and stellar mass ($M_{\rm star}$) of the host galaxies, and declines steeply with increasing $d$ for isolated, star-forming galaxies. $W_r$(2796) exhibits no clear trend for either isolated, quiescent galaxies or non-isolated galaxies. The covering fraction of MgII absorbing gas $\langle \kappa \rangle$ is high with $\langle \kappa \rangle\gtrsim 60$% at $, Comment: 20 pages, 11 figures, accepted for publication in the MNRAS

Objective To assess if there is a difference in the repositioning rate of the EZ-Blocker versus a left-sided double-lumen endobronchial tube (DLT) in patients undergoing thoracic surgery and one-lung ventilation. Design Prospective, randomized. Setting Single center, university hospital. Participants One hundred sixty-three thoracic surgery patients. Interventions Patients were randomized to either EZ-Blocker or a DLT. Measurements and Main Results The primary outcome was positional stability of either the EZ-Blocker or a left-sided double-lumen endobronchial tube, defined as the number of repositionings per hour of surgery and one-lung ventilation. Secondary outcomes included an ordinal isolation score from 1 to 3, in which 1 was poor, up to 3, which represented excellent isolation, and a visual analog postoperative sore throat score (0-100) on postoperative days (POD) one and two. Rate of repositionings per hour during one-lung ventilation and surgical manipulation in left-sided cases was similar between the two devices: 0.08 ± 0.15 v 0.11 ± 0.3 (p = 0.72). In right-sided cases, the rate of repositioning was higher in the EZ-Blocker group compared with DLT: 0.38 ± 0.65 v 0.09 ± 0.21 (p = 0.03). Overall, mean isolation scores for the EZ-Blocker versus the DLT were 2.76 v 2.92 (p = 0.04) in left-sided cases and 2.70 v 2.83 (p = 0.22) in right-sided cases. Median sore throat scores for left sided cases were 0 v 5 (p = 0.13) POD one and 0 v 5 (p = 0.006) POD two for the EZ-Blocker and left-sided DLT, respectively. Conclusion For right-sided procedures, the positional stability of the EZ-Blocker is inferior to a DLT. In left-sided cases, the rate of repositioning for the EZ-Blocker and DLT are not statistically different.

A prediction of the classic active galactic nuclei (AGN) unification model is the presence of ionisation cones with different orientations depending on the AGN type. Confirmations of this model exist for present times, but it is less clear in the early Universe. Here, we use the morphology of giant Ly$\alpha$ nebulae around AGNs at redshift z$\sim$3 to probe AGN emission and therefore the validity of the AGN unification model at this redshift. We compare the spatial morphology of 19 nebulae previously found around type I AGNs with a new sample of 4 Ly$\alpha$ nebulae detected around type II AGNs. Using two independent techniques, we find that nebulae around type II AGNs are more asymmetric than around type I, at least at radial distances $r>30$~physical kpc (pkpc) from the ionizing source. We conclude that the type I and type II AGNs in our sample show evidence of different surrounding ionising geometries. This suggests that the classical AGN unification model is also valid for high-redshift sources. Finally, we discuss how the lack of asymmetry in the inner parts (r$\lesssim$30 pkpc) and the associated high values of the HeII to Ly$\alpha$ ratios in these regions could indicate additional sources of (hard) ionizing radiation originating within or in proximity of the AGN host galaxies. This work demonstrates that the morphologies of giant Ly$\alpha$ nebulae can be used to understand and study the geometry of high redshift AGNs on circum-nuclear scales and it lays the foundation for future studies using much larger statistical samples., Comment: 15 pages, 13 figures, accepted for publication in MNRAS

We present initial results from the Cosmic Ultraviolet Baryon Survey (CUBS). CUBS is designed to map diffuse baryonic structures at redshift z~ 17.2 over a total redshift survey pathlength of dz=9.3, and a number density of n(z)=0.43 (-0.18, +0.26). Considering all absorbers with log N(HI)/cm^-2 > 16.5 leads to n(z)=1.08 (-0.25, +0.31) at z, Comment: 26 pages, 14 figures, MNRAS in press

We report the serendipitous detection of an H$_{2}$-bearing damped Lyman-$��$ absorber at z = 0.576 in the spectrum of the QSO J0111-0316 in the Cosmic Ultraviolet Baryon Survey. Spectroscopic observations from HST-COS in the far-ultraviolet reveal a damped absorber with log[N(HI)/cm^-2] = 20.1 +/- 0.2 and log[N(H$_{2}$)/cm^-2] = 18.97 (-0.06, +0.05). The diffuse molecular gas is found in two velocity components separated by dv = 60 km/s, with >99.9% of the total H$_{2}$ column density concentrated in one component. At a metallicity of $\approx$ 50% of solar, there is evidence for Fe enhancement and dust depletion, with a dust-to-gas ratio $��_{\text{O}} \approx$ 0.4. A galaxy redshift survey conducted with IMACS and LDSS-3C on Magellan reveals an overdensity of nine galaxies at projected distance d, 19 pages, 6 figures. Accepted for publication in ApJ

Galactic-scale winds driven by active galactic nuclei (AGN) are often invoked to suppress star formation in galaxy evolution models, but the mechanisms driving these outflows are hotly debated. Two key AGN feedback models are (1) radiation pressure accelerating cool gas and (2) a hot outflowing wind entraining the ISM. Highly ionized emission-line diagnostics represent a powerful means of differentiating these scenarios because of their sensitivity to the expected compression of the ISM clouds by the hot wind. Here, we report the first spatially resolved UV emission spectroscopy of a prototypical (radio-quiet) quasar-driven superwind around the obscured quasar SDSSJ1356+1026 at z=0.123. We observe ratios of OVI/CIV, NV/CIV, and CIV/HeII that are remarkably similar for outflowing gas clouds, Accepted to ApJ Letters. 11 pages, 5 figures and 1 table