25 results on '"Scrace, Simon"'
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2. Novel regulation of SRC family kinase signalling by RASSF1 isoforms
3. JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations
4. RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis:prev. Amoeboid cells are stem-like and induce non-cell autonomous metastasis in vivo
5. Use of the xCELLigence System for Real-Time Analysis of Changes in Cellular Motility and Adhesion in Physiological Conditions
6. RASSF1C oncogene elicits amoeboid invasion, cancer stemness and invasive EVs via a novel SRC/Rho axis
7. Novel regulation of SRC family kinase signalling by RASSF1 isoforms
8. Abstract 5160: Development of REDX05358, a novel highly selective and potent pan RAF inhibitor and a potential therapeutic for BRAF and RAS mutant tumors
9. Abstract 4123: CRISPR-Cas9 and siRNA screening in primary human immune cells
10. Abstract B66: An integrated immuno-oncology platform using high-throughput cell based assays, gene editing and genomic screens in immune cells
11. Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth
12. TGF-β Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation
13. Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion
14. Identification of novel,in vivoactive Chk1 inhibitors utilizing structure guided drug design
15. Abstract 700: Investigating KRAS synthetic lethal/co-dependency interactions using siRNA and CRISPR
16. Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution
17. Structure-guided design of α-amino acid-derived Pin1 inhibitors
18. RASSF Signalling and DNA Damage: Monitoring the Integrity of the Genome?
19. Corrigendum to “Structure-guided design of α-amino acid-derived Pin1 inhibitors” [Bioorg. Med. Chem. Lett. 20 (2010) 586]
20. Abstract 4432: Discovery of novel Pin1 inhibitors by structure-guided fragment evolution that downregulate cyclin D1 expression in PC-3 prostate cancer cells
21. Abstract C207: Checkpoint abrogation and potentiation of cytotoxic chemotherapeutics with a novel checkpoint kinase 1 inhibitor
22. ATM Regulates a RASSF1A-Dependent DNA Damage Response
23. Transient treatment with CDK inhibitors eliminates proliferative potential even when their abilities to evoke apoptosis and DNA damage are blocked
24. Use of the xCELLigence System for Real-Time Analysis of Changes in Cellular Motility and Adhesion in Physiological Conditions.
25. Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design.
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