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25 results on '"Scotto, Pietro"'

10. CL316,243, a β3-adrenergic receptor agonist, induces muscle hypertrophy and increased strength

Author

Puzzo, Daniela, primary, Raiteri, Roberto, additional, Castaldo, Clotilde, additional, Capasso, Raffaele, additional, Pagano, Ester, additional, Tedesco, Mariateresa, additional, Gulisano, Walter, additional, Drozd, Lisaveta, additional, Lippiello, Pellegrino, additional, Palmeri, Agostino, additional, Scotto, Pietro, additional, and Miniaci, Maria Concetta, additional

Published
2016
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16. Oral communications

Author

Fiorito, Graziano, primary, Rosciano, Vincenzo, additional, Scotto, Pietro, additional, and Valsecchi, Paola, additional

Published
1994
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25. Role of hippocampus in polymodal-cue guided tasks in rats

Author

Marcellino Monda, Pellegrino Lippiello, Maria Concetta Miniaci, Pietro Scotto, Miniaci, Maria, Lippiello, Pellegrino, Marcellino, Monda, SCOTTO DI VETTIMO, Pietro, Miniaci, Maria Concetta, Monda, Marcellino, and Scotto, Pietro

Subjects
Male, Electrolytic lesion, Dorsal hippocampu, Hippocampus, Sensory system, Hippocampal formation, Polymodal cue, Task (project management), Lesion, 03 medical and health sciences, 0302 clinical medicine, Stimulus modality, Reward, Memory, medicine, Learning, Animals, 0501 psychology and cognitive sciences, Rats, Long-Evans, 050102 behavioral science & comparative psychology, Maze Learning, Molecular Biology, Neuroscience (all), Overtraining, General Neuroscience, 05 social sciences, Association Learning, Content-addressable memory, medicine.disease, Rats, Neurology (clinical), medicine.symptom, Cues, Psychology, Neuroscience, 030217 neurology & neurosurgery, Developmental Biology
Abstract

To examine how signals from different sensory modalities are integrated to generate an appropriate goal-oriented behavior, we trained rats in an eight-arm radial maze to visit a cue arm provided with intramaze cues from different sensory modalities, i.e. visual, tactile and auditory, in order to obtain a reward. When the same rats were then examined on test trials in which the cue arm contained one of the stimuli that the animals were trained with (i.e. light, sound or rough sheet), they showed a significant impairment with respect to the performance on the polymodal-cue task. The contribution of the dorsal hippocampus to the acquisition and retention of polymodal-cue guided task was also examined. We found that rats with dorsal hippocampal lesions before training showed a significant deficit in the acquisition of polymodal-cue oriented task that improved with overtraining. The selective lesion of the dorsal hippocampus after training disrupted memory retention, but the animals' performance improved following retraining of the polymodal task. All hippocampal lesioned rats displayed an impaired performance on the unimodal test. These findings suggest that the dorsal hippocampus contributes to the processing of multimodal sensory information for the associative memory formation and consolidation.

Published
2015

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