Search

Your search keyword '"Scorza R"' showing total 919 results
Start Over Author "Scorza R"
919 results on '"Scorza R"'

1. Variants of PBEF predispose to systemic sclerosis and pulmonary arterial hypertension development

Author

Mayes M, Coenen MJH, Airò P, Gonzalez-Gay M A, Ortego-Centeno N, Carreira P, Fonollosa V, Simeon C P, Scorza R, Kiener H, Riemekasten G, Fonseca C, Denton C, Hunzelman N, Worthington J, Hesselstrand R, Herrick A, Brouwer C, Rueda B, Geurts-van Bon L, Niederer F, Beretta L, Vonk M C, Broen JCA, Gourh P, Kyburz D, Arnett F C, Martin J, and Radstake TRDJ

Subjects
Medicine
Published
2010
Full Text
View/download PDF

2. Polymorphisms in the interleukin 4, interleukin 13 and corresponding receptor genes are not associated with Systemic Sclerosis and do not influence gene expression

Author

Aliprantis A, Coenen MJH, Airò P, Gonzalez-Gay M A, Ortego-Centeno N, Carreira P, Fonollosa V, Scorza R, Simeon C P, Kiener H, Riemekasten G, Hunzelmann N, Worthington J, Herrick A, Rueda B, Beretta L, Vonk M C, Dieude P, Broen JCA, Martin J, Allanore Y, and Radstake TRDJ

Subjects
Medicine
Published
2010
Full Text
View/download PDF

3. A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with Systemic Sclerosis in a large European cohort

Author

Airó P, Lie B A, Palm Ø, Nordin A, Padykov L, Claes K, Denton C, Fonseca C, Madhok R, Shiels P, Chee M M, Schuerwegh A J, Voskuyl A E, De Langhe E, Westhovens R, Smith V, De Keyser F, Houssiau F, Koeleman B P, Coenen MJH, Witte T, Riemekasten G, Hesselstrand R, González-Gay M A, Pros A, García de la Peña P, Follonosa V, Egurbide M V, Fernández-Nebro A, Gallego M, Castellví I, García-Hernández F J, Gómez-Gracia I, Román-Ivorra J A, Tolosa C, Rodríguez L, Vicente-Rabaneda E, González-Escribano M F, Navarrete N, Camps M T, Carreira P, Espinosa G, Ortego-Centeno N, Vonk M C, Beretta L, Simeon C P, Broen JCA, Bossini-Castillo L, Scorza R, van Laar J M, Hunzelmann N, Kreuter A, Herrick A, Worthington J, Radstake TRDJ, Martín J, and Rueda B

Subjects
Medicine
Published
2010
Full Text
View/download PDF

4. ACE inhibitors in SSc patients display a risk factor for scleroderma renal crisis—a EUSTAR analysis

Author

Bütikofer L, Varisco PA, Distler O, Kowal-Bielecka O, Allanore Y, Riemekasten G, Villiger PM, Adler S, Avouac J, Walker UA, Guiducci S, Airò P, Hachulla E, Valentini G, Carreira PE, Cozzi F, Gurman AB, Braun-Moscovici Y, Damjanov N, Ananieva LP, Scorza R, Jimenez S, Busquets J, Li M, Müller-Ladner U, Maurer B, Tyndall A, Lapadula G, Iannone F, Becvar R, Sierakowsky S, Bielecka OK, Cutolo M, Sulli A, Cuomo G, Vettori S, Rednic S, Nicoara I, Vlachoyiannopoulos P, Montecucco C, Caporali R, Novak S, Czirják L, Varju C, Chizzolini C, Kucharz EJ, Kotulska A, Kopec-Medrek M, Widuchowska M, Rozman B, Mallia C, Coleiro B, Gabrielli A, Farge D, Hij A, Hesselstrand R, Scheja A, Wollheim F, Martinovic D, Govoni M, Monaco AL, Hunzelmann N, Pellerito R, Bambara LM, Caramaschi P, Black C, Denton C, Henes J, Santamaria VO, Heitmann S, Krasowska D, Seidel M, Oleszowsky M, Burkhardt H, Himsel A, Salvador MJ, Stamenkovic B, Stankovic A, Tikly M, Starovoytova MN, Engelhart M, Strauss G, Nielsen H, Damgaard K, Szücs G, Mendoza AZ, de la Puente Buijdos C, Sifuentes Giraldo WA, Midtvedt Ø, Garen T, Launay D, Valesini G, Riccieri V, Ionescu RM, Opris D, Groseanu L, Wigley FM, Mihai CM, Cornateanu RS, Ionitescu R, Gherghe AM, Gorga M, Dobrota R, Bojinca M, Schett G, Distler JHW, Meroni P, Zeni S, Mouthon L, De Keyser F, Smith V, Cantatore FP, Corrado A, Ullman S, Iversen L, Pozzi MR, Eyerich K, Hein R, Knott E, Szechinski J, Wiland P, Szmyrka-Kaczmarek M, Sokolik R, Morgiel E, Krummel-Lorenz B, Saar P, Aringer M, Günther C, Anic B, Baresic M, Mayer M, Radominski SC, de Souza Müller C, Azevedo VF, Agachi S, Groppa L, Chiaburu L, Russu E, Zenone T, Stebbings S, Highton J, Stamp L, Chapman P, Baron M, O'Donnell J, Solanki K, Doube A, Veale D, O'Rourke M, Loyo E, Rosato E, Pisarri S, Tanaseanu CM, Popescu M, Dumitrascu A, Tiglea I, Chirieac R, Ancuta C, Furst DE, Kafaja S, de la Peña Lefebvre PG, Rubio SR, Exposito MV, Sibilia J, Chatelus E, Gottenberg JE, Chifflot H, Litinsky I, Venalis A, Butrimiene I, Venalis P, Rugiene R, Karpec D, Kerzberg E, Montoya F, Cosentino V, Castellvi I., Publica, Bütikofer, L, Varisco, Pa, Distler, O, Kowal-Bielecka, O, Allanore, Y, Riemekasten, G, Villiger, Pm, Adler, S, Avouac, J, Walker, Ua, Guiducci, S, Airò, P, Hachulla, E, Valentini, G, Carreira, Pe, Cozzi, F, Gurman, Ab, Braun-Moscovici, Y, Damjanov, N, Ananieva, Lp, Scorza, R, Jimenez, S, Busquets, J, Li, M, Müller-Ladner, U, Maurer, B, Tyndall, A, Lapadula, G, Iannone, F, Becvar, R, Sierakowsky, S, Bielecka, Ok, Cutolo, M, Sulli, A, Cuomo, G, Vettori, S, Rednic, S, Nicoara, I, Vlachoyiannopoulos, P, Montecucco, C, Caporali, R, Novak, S, Czirják, L, Varju, C, Chizzolini, C, Kucharz, Ej, Kotulska, A, Kopec-Medrek, M, Widuchowska, M, Rozman, B, Mallia, C, Coleiro, B, Gabrielli, A, Farge, D, Hij, A, Hesselstrand, R, Scheja, A, Wollheim, F, Martinovic, D, Govoni, M, Monaco, Al, Hunzelmann, N, Pellerito, R, Bambara, Lm, Caramaschi, P, Black, C, Denton, C, Henes, J, Santamaria, Vo, Heitmann, S, Krasowska, D, Seidel, M, Oleszowsky, M, Burkhardt, H, Himsel, A, Salvador, Mj, Stamenkovic, B, Stankovic, A, Tikly, M, Starovoytova, Mn, Engelhart, M, Strauss, G, Nielsen, H, Damgaard, K, Szücs, G, Mendoza, Az, de la Puente Buijdos, C, Sifuentes Giraldo, Wa, Midtvedt, Ø, Garen, T, Launay, D, Valesini, G, Riccieri, V, Ionescu, Rm, Opris, D, Groseanu, L, Wigley, Fm, Mihai, Cm, Cornateanu, R, Ionitescu, R, Gherghe, Am, Gorga, M, Dobrota, R, Bojinca, M, Schett, G, Distler, Jhw, Meroni, P, Zeni, S, Mouthon, L, De Keyser, F, Smith, V, Cantatore, Fp, Corrado, A, Ullman, S, Iversen, L, Pozzi, Mr, Eyerich, K, Hein, R, Knott, E, Szechinski, J, Wiland, P, Szmyrka-Kaczmarek, M, Sokolik, R, Morgiel, E, Krummel-Lorenz, B, Saar, P, Aringer, M, Günther, C, Anic, B, Baresic, M, Mayer, M, Radominski, Sc, de Souza Müller, C, Azevedo, Vf, Agachi, S, Groppa, L, Chiaburu, L, Russu, E, Zenone, T, Stebbings, S, Highton, J, Stamp, L, Chapman, P, Baron, M, O'Donnell, J, Solanki, K, Doube, A, Veale, D, O'Rourke, M, Loyo, E, Rosato, E, Pisarri, S, Tanaseanu, Cm, Popescu, M, Dumitrascu, A, Tiglea, I, Chirieac, R, Ancuta, C, Furst, De, Kafaja, S, de la Peña Lefebvre, Pg, Rubio, Sr, Exposito, Mv, Sibilia, J, Chatelus, E, Gottenberg, Je, Chifflot, H, Litinsky, I, Venalis, A, Butrimiene, I, Venalis, P, Rugiene, R, Karpec, D, Kerzberg, E, Montoya, F, Cosentino, V, and Castellvi, I.

Subjects
INVOLVEMENT, Male, Hypertension, Renal, ACE inhibitors, lcsh:Diseases of the musculoskeletal system, Scleroderma Renal Crisis, MULTICENTER, Angiotensin-Converting Enzyme Inhibitors, Scleroderma, Scleroderma renal crisis, 0302 clinical medicine, Risk Factors, Medicine and Health Sciences, Medicine, 030212 general & internal medicine, Prospective Studies, 610 Medicine & health, Renal, Antihypertensive drugs, Outcome, antihypertensive drugs, arterial hypertension, outcome, scleroderma renal crisis, Incidence (epidemiology), Incidence, Hazard ratio, Acute Kidney Injury, Middle Aged, Europe, Treatment Outcome, Population Surveillance, Cohort, Hypertension, Female, 360 Social problems & social services, Proto-oncogene tyrosine-protein kinase Src, Research Article, Arterial hypertension, medicine.medical_specialty, 03 medical and health sciences, ENDOTHELIN-1, Internal medicine, Humans, Risk factor, Aged, 030203 arthritis & rheumatology, Scleroderma, Systemic, business.industry, SYSTEMIC-SCLEROSIS, Systemic, medicine.disease, Concomitant, lcsh:RC925-935, business
Abstract

Objectives To investigate the effect of ACE inhibitors (ACEi) on the incidence of scleroderma renal crisis (SRC) when given prior to SRC in the prospectively collected cohort from the European Scleroderma Trial and Research Group (EUSTAR). Methods SSc patients without prior SRC and at least one follow-up visit were included and analyzed regarding SRC, arterial hypertension, and medication focusing on antihypertensive medication and glucocorticoids (GC). Results Out of 14,524 patients in the database, we identified 7648 patients with at least one follow-up. In 27,450 person-years (py), 102 patients developed SRC representing an incidence of 3.72 (3.06–4.51) per 1000 py. In a multivariable time-to-event analysis adjusted for age, sex, disease severity, and onset, 88 of 6521 patients developed SRC. The use of ACEi displayed an increased risk for the development of SRC with a hazard ratio (HR) of 2.55 (95% confidence interval (CI) 1.65–3.95). Adjusting for arterial hypertension resulted in a HR of 2.04 (95%CI 1.29–3.24). There was no evidence for an interaction of ACEi and arterial hypertension (HR 0.83, 95%CI 0.32–2.13, p = 0.69). Calcium channel blockers (CCB), angiotensin receptor blockers (ARB), endothelin receptor antagonists, and GC—mostly in daily dosages below 15 mg of prednisolone—did not influence the hazard for SRC. Conclusions ACEi in SSc patients with concomitant arterial hypertension display an independent risk factor for the development of SRC but are still first choice in SRC treatment. ARBs might be a safe alternative, yet the overall safety of alternative antihypertensive drugs in SSc patients needs to be further studied.

Published
2020

5. Peaches

Author

Hancock, J.F., Scorza, R., Lobos, G.A., and Hancock, James F., editor

Published
2008
Full Text
View/download PDF

6. Peach

Author

Abbott, A. G., Arús, P., Scorza, R., and Kole, Chittaranjan, editor

Published
2007
Full Text
View/download PDF

7. Figura

Author

Cuccodoro E., Marzo R., Ghelfi L., Scorza R., De Bonis A., Leo L., Colizzi M., Cuccodoro E., Marzo R., Ghelfi L., Scorza R., De Bonis A., Leo L., Colizzi M., Cuccodoro, E., Marzo, R., Ghelfi, L., Scorza, R., De Bonis, A., Leo, L., and Colizzi, M.

Published
2021

14. Supplement to: Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis

Author

van Bon, L., Affandi, A. J., Broen, J., Christmann, R. B., Marijnissen, R. J., Stawski, L., Farina, G. A., Stifano, G., Mathes, A. L., Cossu, M., York, M., Collins, C., Wenink, M., Huijbens, R., Hesselstrand, R., Saxne, T., DiMarzio, M., Wuttge, D., Agarwal, S. K., Reveille, J. D., Assassi, S., Mayes, M., Deng, Y., Drenth, J. P.H., de Graaf, J., den Heijer, M., Kallenberg, C. G.M., Bijl, M., Loof, A., van den Berg, W. B., Joosten, L. A.B., Smith, V., de Keyser, F., Scorza, R., Lunardi, C., van Riel, P. L.C.M., Vonk, M., van Heerde, W., Meller, S., Homey, B., Beretta, L., Roest, M., Trojanowska, M., Lafyatis, R., and Radstake, T. R.D.J.

Published
2014

17. Opposed independent effects and epistasis in the complex association of IRF5 to SLE

Author

Ferreiro-Neira, I, Calaza, M, Alonso-Perez, E, Marchini, M, Scorza, R, Sebastiani, G D, Blanco, F J, Rego, I, Pullmann, Jr, R, Pullmann, R, Kallenberg, C G, Bijl, M, Skopouli, F N, Mavromati, M, Migliaresi, S, Barizzone, N, Ruzickova, S, Dostal, C, Schmidt, R E, Witte, T, Papasteriades, C, Kappou-Rigatou, I, Endreffy, E, Kovacs, A, Ordi-Ros, J, Balada, E, Carreira, P, Gomez-Reino, J J, and Gonzalez, A

Published
2007
Full Text
View/download PDF

24. A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators

Author

Broen, J. C. A., Bossini-Castillo, L., van Bon, L., Vonk, M. C., Knaapen, H., Beretta, L., Rueda, B., Hesselstrand, R., Herrick, A., Worthington, J., Hunzelman, N., Denton, C. P., Fonseca, C., Riemekasten, G., Kiener, H. P., Scorza, R., Simeón, C. P., Ortego-Centeno, N., Gonzalez-Gay, M. A., Airò, P., Coenen, M. J. H., Martín, J., and Radstake, T. R. D. J.

Published
2012
Full Text
View/download PDF

28. Polymorphisms in the interleukin 4, interleukin 13 and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression

Author

Broen, J C A, Dieude, P, Vonk, M C, Beretta, L, Rueda, B, Herrick, A, Worthington, J, Hunzelmann, N, Riemekasten, G, Kiener, H, Scorza, R, Simeon, C P, Fonollosa, V, Carreira, P, Ortego-Centeno, N, Gonzalez-Gay, M A, Airoʼ, P, Coenen, M J H, Aliprantis, A, Martin, J, Allanore, Y, and Radstake, T R D J

Published
2011
Full Text
View/download PDF

29. Variants of PBEF predispose to systemic sclerosis and pulmonary arterial hypertension development

Author

Broen, J C A, Gourh, P, Vonk, M C, Beretta, L, Niederer, F, Rueda, B, Geurts-van Bon, L, Brouwer, C, Hesselstrand, R, Herrick, A, Worthington, J, Hunzelman, N, Fonseca, Denton C, Riemekasten, G, Kiener, H, Scorza, R, Simeon, C P, Fonollosa, V, Carreira, P, Ortego-Centeno, N, Gonzalez-Gay, M A, Airoʼ, P, Coenen, M J H, Mayes, M, Kyburz, D, Arnett, F C, Martin, J, and Radstake, T R D J

Published
2011
Full Text
View/download PDF

30. Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis

Author

Diaz-Gallo, LM, Gourh, P, Broen, J, Simeon, C, Fonollosa, V, Ortego-Centeno, N, Agarwal, S, Vonk, MC, Coenen, M, Riemekasten, G, Hunzelmann, N, Hesselstrand, R, Tan, FK, Reveille, JD, Assassi, S, García-Hernandez, FJ, Carreira, P, Camps, MT, Fernandez-Nebro, A, de la Peña, P Garcia, Nearney, T, Hilda, D, González-Gay, MA, Airo, P, Beretta, L, Scorza, R, Herrick, A, Worthington, J, Pros, A, Gómez-Gracia, I, Trapiella, L, Espinosa, G, Castellvi, I, Witte, T, de Keyser, F, Vanthuyne, M, Mayes, MD, Radstake, TRDJ, Arnett, FC, Martin, J, and Rueda, B

Published
2011
Full Text
View/download PDF

32. BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians

Author

Rueda, B, Gourh, P, Broen, J, Agarwal, S K, Simeon, C, Ortego-Centeno, N, Vonk, M C, Coenen, M, Riemekasten, G, Hunzelmann, N, Hesselstrand, R, Tan, F K, Reveille, J D, Assassi, S, Garcia-Hernandez, F J, Carreira, P, Camps, M, Fernandez-Nebro, A, de la Peña, P Garcia, Nearney, T, Hilda, D, Gónzalez-Gay, M A, Airo, P, Beretta, L, Scorza, R, Radstake, T R, Mayes, M D, Arnett, F C, and Martin, J

Published
2010
Full Text
View/download PDF

34. The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype

Author

Rueda, B, Broen, J, Simeon, C, Hesselstrand, R, Diaz, B, Suárez, H, Ortego-Centeno, N, Riemekasten, G, Fonollosa, V, Vonk, MC, van den Hoogen, FHJ, Sanchez-Román, J, Aguirre-Zamorano, MA, García-Portales, R, Pros, A, Camps, MT, Gonzalez-Gay, MA, Coenen, MJH, Airo, P, Beretta, L, Scorza, R, van Laar, J, Gonzalez-Escribano, MF, Nelson, JL, Radstake, TRDJ, and Martin, J

Published
2009

36. Abstracts of presentations on plant protection issues at the xth international congress of virology: August 11–16,1996 Binyanei haOoma, Jerusalem, Israel Part 2 Plenary Lectures

Author

Ramirez, E., Hernádez, A., Ham, E., Barrón, B. L., Ding, S. W., Li, W. X., Shi, B. J., Symons, R. H., Li, Q., Ryu, K. H., Palukaitis, P., Kaplan, I. B., Palukaitis, P., Kaplan, I. B., Palukaitis, P., Gal-On, A., Kunhara, J., Otsubo, T., Tomaru, K., Tsuda, S., Kinta, M., Lin, T., Johnson, J. E., Porta, C., Taylor, K. M., Spall, V. E., Lomonossoff, G. P., Spall, V. E., Porta, C., Lomonossoff, G. P., Gal-On, A., Meiri, E., Raccah, B., Gaba, V., Ikegami, M., Kawashima, H., Murayama, A., Natsuaki, T., Kageyama, Y., Sugimura, N., Thole, V., Bol, J. F., Deiman, B. A. L. M., Koenen, A. K., Pleij, C. W. A., Chaleeprom, W., Bateson, M. F., Dale, J. L., Badge, J. L., Foster, G. D., Brunt, A. A., Robinson, D., Schubert, J., Rabenstein, F., Merits, A., Yeh, Shyi-Dong, Chiang, Chu-Hui, Wang, Ching-Hsien, Chiang, Chu-Hui, Yeh, Shyi-Dong, Golshani, A., Ivanov, I. G., AbouHaidar, M. G., Rodoni, B. C., Harding, R. M., Bateson, M. F., Dale, J. L., Oertel, U., Fuchs, E., Schubert, J., Yang, S. J., Revere, F., Walter, J., Le Gall, O., Dunez, J., Candresse, T., Lot, H., Souche, S., Kasschau, Kristin D., Carrington, James C., Chiang, A. N., Turner, N. E., Hwang, D. J., Chachulska, A. M., Zagórski, W., Robaglia, C., Chrzanowska, M., Truve, E., Tamm, T., Saarma, M., Makinen, K., Wang, Aiming, Carrier, Karma, Wieczorek, Andrew, Huguenot, Claire, Sanfacon, Helene, Wurscher, M. A., Christensen, F. E., Prody, G. A., Sanchez-Navarro, J. A., Pallas, V., Carson, R., Dagless, E., Lock, S., Turner, R., Foster, G. D., Badge, J. L., Adams, M., Antoniw, J., Brunt, A. A., Phillips, S., Kashiwazaki, S., Seal, S., Karamagioli, M., Druka, Amis, Makhdoom, Rahat, Yitang, Yan, Hull, Roger, Kikkert, M., Bodegom, P., Storms, M., van Lent, J., Kormelink, R., Goldbach, R., De Haan, P., De Rover, A. R., Van Schepen, A., Gielen, J. J. L., Van Grinsven, M. Q. J. M., Livneh, O., Vardi, E., Kuznetsova, L., Aliskevicius, E., Stram, Y., Sela, I., Dinant, S., Kusiak, C., Blaise, F., Chupeau, Y., Astier, S., Albouy, J., Clifford, T. B., Taylor, S. C., Stratford, R., Foster, G. D., Xiao, X. W., Frenkel, M. J., Chu, P., Tabe, L., Shukla, D. D., Ward, C. W., Hwang, Duk-Ju, Turner, Nilgun, Taylor, S. C., Mooney, A., MacFarlane, S. A., Twell, D., Foster, G. D., Jacquet, C., Ravelonandro, M., Bachelier, J. C., Dunez, J., Almási, A., Böddi, B., Szigeti, Z., Ekes, M., Gaborianvi, R., Yankulova, Margarita, Ivanova, Lidia, Adam, G., Guelemerov, S., Nikolaeva, Velitchka, Atanassov, A., Prins, Marcel, de Haan, Peter, Goldbach, Rob, Duan, Y. P., Powell, C. A., Purcifull, D. E., Hiebert, E., Levine, B., Faktor, O., Zeituny, Silvy, Edelbaum, Orit, Sela, L., Marano, Maria-Rosa, Ratcliff, Frank, Baulcombe, David C., van Oers, Monique M., Linthorst, Huub J. M., Bol, John F., Schillberg, S., Zimmermann, S., Drossard, J., Schumann, D., Nahring, J., Fischer, R., Lapidot, Moshe, Arce-Johnson, Patricio, Rivera-Bustamante, Rafael, Beachy, Roger N., Cassidy, Brandt G., Flasinski, Stanislaw, Hajimorad, M. R., Wesley, Varsha, Angel-Diaz, J., Mayo, M. A., Hafner, G. J., May, G. D., Becker, D. K., Harding, R. M., Arntzen, C. J., Dale, J. L., Taylor, S. C., Porter, J., Foster, G. D., Palukaitis, P., Hellwald, K. H., Banerjee, N., Zaitlin, M., Gal-On, A., Wolf, D., Faure, J. E., Pilowsky, M., Cohen, S., Zelcer, A., Hardi, V., Tomassoli, L., Kaniewski, W. K., Mitsky, T., Barba, M., Hou, Y. -M., Ursin, V. M., Sanders, R., Gilbertson, R. L., Gruden, Kristina, Štrukelj, Borut, Brzin, Joze, Ravnikar, Maja, Maganja, Darja Barlič, Kregar, Igor, Maki-Valkama, T., Pehu, T., Valkonen, J., Lento, K., Pehu, E., Zaitlin, M., Kaniewski, W. K., Lawson, E. C., Feldman, J., Zalewski, J., Saarma, M., Kuittinen, T., Valkonen, J., Atiri, G. I., Romero, A., Arroyo, R., Soto, M. J., Martínez-Zapater, J. M., Ponz, F., Gilardi, P., López, L., García-Luque, I., Serra, M. T., Pang, Sheng-Zhi, Jan, Fuh-Jyh, Carney, Kim, Tricoli, David M., Quemada, Hector D., Gonsalves, Dennis, Aboul-Ata, A. E., Thouvenel, J. -C., Marshall, D., Abo-El-Saad, Sh., Satour, M., Mazithulela, G., Mehlo, L., Gahakwa, D., Leech, M., Boulton, M. I., Davies, J. W., Christou, P., Huet, H., Sivamani, E., Ong, C. A., Chen, L., de Kochko, A., Beachy, R. N., Fauquet, C. M., Sithisarn-Burns, P., Maugeri, M. M., Dale, J. L., Smith, G. R., Harding, R. M., Handley, J. A., Harding, R. M., Smith, G. R., Dale, J. L., Graichen, K., Peterka, J., Chu, Paul, Larkin, Phil, Higgins, T. J., Wylie, S., Jones, M. G. K., Somsap, V., Loo, H. P., Li, D., Mathews, A., Jones, M. G. K., Dwyer, G. I., Jones, M. G. K., McCarthy, P. L., Hansen, J., Shiel, P. J., Zemetra, R. S., Wyatt, S. D., Berger, P. H., Ford, C., Collins, N., Rathjen, J., Shams-Bakhsh, M., Paltridge, N., Symons, R. H., Aboul-Ata, A. E., Makkouk, K. M., El-Saied, M. A., El-Hariry, M., Salem, G., Soliman, N. H., Rishi, Narayan, Lodhi, G. P., Bishnoi, S. S., Sangwan, R. B., Sijen, Titia, Wellink, Joan, van Kammen, Ab, Ravelonandro, M., Scorza, R., Bachelier, J., Callahan, A., Levy, L., Dunez, J., Polák, J., Oukropec, I., Kominek, P., Bitoova, M., Cardol, Erwin, Prins, Marcel, Kormelink, Richard, Goldbach, Rob, Baulcombe, D. C., English, J. J., Davenport, G., Ruiz-Perez, T., Mueller, E., Truve, E., Nigul, L., Saarma, M., Kelve, M., Fedorkin, O. N., Denisenko, O. N., Zelenina, D. A., Morozov, S. Yu., Atabekov, J. G., Laliberté, J. -F., Wittmann, S., Plante, Daniel, Fortin, Marc G., Chatel, H., Rodriguez-Alvarado, G., Garcia-Arenal, F., Roossinck, M. J., Palukaitis, P., Roossinck, M. J., Palukaitis, P., Gellatly, D. L., AbouHaidar, M. G., Rasochova, L., Aulik, M., Passmore, B., Falk, B., Miller, W. A., Lin, Na-Sheng, Lin, Biing-Yuan, Hsu, Yau-Heiu, Tamada, T., Kiguchi, T., Saito, M., Kusume, T., Uchino, H., Taliansky, M., Robinson, D., DiSerio, F., Daròs, J. A., Ragozzino, A., Floras, R., Hohn, Thomas, Chen, Gang, Rothnie, Helen, Corsten, Sandra, Fütterer, Johannes, Mikhailov, M. V., Bishop, D. H. L., and Roy, P.

Published
1997
Full Text
View/download PDF

38. Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study

Author

Elhai, M, Boubaya, M, Distler, O, Smith, V, Matucci-Cerinic, M, Sancho, JJ, Truchetet, ME, Braun-Moscovici, Y, Iannone, F, Novikov, PI, Lescoat, A, Siegert, E, Castellvi, I, Airo, P, Vettori, S, Langhe, E, Hachulla, E, Erler, A, Ananieva, L, Krusche, M, Lopez-Longo, FJ, Distler, JHW, Hunzelmann, N, Hoffmann-Vold, AM, Riccieri, V, Hsu, VM, Pozzi, MR, Ancuta, C, Rosato, E, Mihai, C, Kuwana, M, Saketkoo, LA, Chizzolini, C, Hesselstrand, R, Ullman, S, Yavuz, S, Rednic, S, Caimmi, C, Bloch-Queyrat, C, Allanore, Y, Guiducci, S, Walker, UA, Kyburz, D, Lapadula, G, Maurer, B, Jordan, S, Dobrota, R, Becvar, R, Sierakowsky, S, Bielecka, OK, Sulli, A, Cutolo, M, Cuomo, G, Nicoara, I, Kahan, A, Vlachoyiannopoulos, PG, Montecucco, CM, Caporali, R, Stork, J, Inanc, M, Carreira, PE, Novak, S, Czirjak, L, Varju, C, Kucharz, EJ, Kotulska, A, Kopec-Medrek, M, Widuchowska, M, Cozzi, F, Rozman, B, Mallia, C, Coleiro, B, Gabrielli, A, Farge, D, Wu, C, Marjanovic, Z, Faivre, H, Hij, D, Dhamadi, R, Wollheim, F, Scheja, A, Wuttge, DM, Andreasson, K, Martinovic, D, Balbir-Gurman, A, Trotta, F, Lo Monaco, A, Pellerito, R, Mauriziano, O, Caramaschi, P, Morovic-Vergles, J, Black, C, Denton, C, Damjanov, N, Henes, J, Santamaria, VO, Heitmann, S, Krasowska, D, Matthias, Hasler, P, Burkhardt, H, Himsel, A, Bajocchi, G, Da Silva, JAP, Salvador, MJ, Stamenkovic, B, Stankovic, A, Selmi, CF, De Santis, M, Tikly, M, Denisov, LN, Herrick, A, Muller-Ladner, U, Frerix, M, Tarner, I, Scorza, R, Puppo, F, Engelhart, M, Strauss, G, Nielsen, H, Damgaard, K, Szucs, G, Mendoza, AZ, de la Puente, C, Giraldo, WAS, Midtvedt, O, Reiseter, S, Garen, T, Launay, D, Valesini, G, Ionescu, RM, Groseanu, L, Opris, D, Cornateanu, RS, Ionitescu, R, Gherghe, AM, Soare, A, Gorga, M, Bojinca, M, Milicescu, M, Sunderkotter, C, Kuhn, A, Sandorfi, N, Schett, G, Beyer, C, Meroni, P, Ingegnoli, F, Mouthon, L, De Keyser, F, Melsens, K, Cantatore, FP, Corrado, A, Iversen, L, von Muhlen, CA, Bohn, JM, Lonzetti, LS, Eyerich, K, Hein, R, Knott, E, Wiland, P, Szmyrka-Kaczmarek, M, Sokolik, R, Morgiel, E, Madej, M, Houssiau, FA, Krummel-Lorenz, B, Saar, P, Aringer, M, Gunther, C, Westhovens, R, Lenaerts, J, Anic, B, Baresic, M, Mayer, M, Uprus, M, Otsa, K, Granel, B, Muller, CD, Radominski, SC, Azevedo, VF, Jimenez, S, Busquets, J, Agachi, S, Groppa, L, Chiaburu, L, Russu, E, Popa, S, Zenone, T, Pileckyte, M, Mathieu, A, Vacca, A, Sampaio-Barros, PD, Yoshinari, NH, Marangoni, RG, Martin, P, Fuocco, L, Stebbings, S, Highton, J, Chapman, P, O'Donnell, J, Stamp, L, Doube, A, Solanki, K, Veale, D, O'Rourke, M, Loyo, E, Li, MT, Mohamed, WAAA, Amoroso, A, Gigante, A, Oksel, F, Yargucu, F, Tanaseanu, CM, Popescu, M, Dumitrascu, A, Tiglea, I, Foti, R, Chirieac, R, Furst, D, Villiger, P, Adler, S, van Laar, J, Kayser, C, Fathi, N, Hassanien, M, Lefebvre, PGD, Rubio, SR, Exposito, MV, Chatelus, E, Sibilia, J, Gottenberg, JE, Chifflot, H, Litinsky, I, Emery, P, Buch, M, Del Galdo, F, Venalis, A, Butrimiene, I, Venalis, P, Rugiene, R, Karpec, D, Lasky, JA, Cosentino, V, Kerzberg, E, Montoya, F, Bianchi, W, Carneiro, S, Maretti, GB, Bianchi, DV, Limonta, M, Lupi, ALBE, Lupi, E, Rosner, I, Rozenbaum, M, Slobodin, G, Boulman, N, Rimar, D, Couto, M, Kahl, S, Chen, F, McCloskey, D, Malveaux, H, Spertini, F, Ribi, C, Buss, G, Martin, T, Guffroy, A, Poindron, V, Chotchaeva, F, Mukhin, NA, Moiseev, S, EUSTAR Network, Elhai, Muriel, Boubaya, Marouane, Distler, Oliver, Smith, Vanessa, Matucci-Cerinic, Marco, Alegre Sancho, Juan José, Truchetet, Marie-Elise, Braun-Moscovici, Yolanda, Iannone, Florenzo, Novikov, Pavel I, Lescoat, Alain, Siegert, Elise, Castellví, Ivan, Airó, Paolo, Vettori, Serena, De Langhe, Ellen, Hachulla, Eric, Erler, Anne, Ananieva, Lidia, Krusche, Martin, López-Longo, F. J., Distler, Jörg H W, Hunzelmann, Nicola, Hoffmann-Vold, Anna-Maria, Riccieri, Valeria, Hsu, Vivien M, Pozzi, Maria R, Ancuta, Codrina, Rosato, Edoardo, Mihai, Carina, Kuwana, Masataka, Saketkoo, Lesley Ann, Chizzolini, Carlo, Hesselstrand, Roger, Ullman, Susanne, Yavuz, Sule, Rednic, Simona, Caimmi, Cristian, Bloch-Queyrat, Coralie, Allanore, Yannick, and Cuomo, Giovanna

Subjects
Male, Vital capacity, systemic sclerosis, Pulmonary Fibrosis, Vital Capacity, Scleroderma, lung fibrosis, rituximab, skin fibrosis, immune system diseases, DLCO, hemic and lymphatic diseases, Immunology and Allergy, Medicine, Prospective Studies, Registries, skin and connective tissue diseases, Prospective cohort study, Lung, skin fibrosi, Skin, ddc:616, integumentary system, Orvostudományok, Middle Aged, Respiratory Function Tests, lung fibrosis, rituximab, skin fibrosis, systemic sclerosis, Treatment Outcome, lung fibrosi, Antirheumatic Agents, Systemic sclerosis, Rituximab, Female, systemic sclerosi, medicine.drug, Adult, medicine.medical_specialty, Immunology, Klinikai orvostudományok, General Biochemistry, Genetics and Molecular Biology, FEV1/FVC ratio, Rheumatology, Internal medicine, Humans, Adverse effect, Propensity Score, Aged, Biochemistry, Genetics and Molecular Biology (all), Scleroderma, Systemic, Skin fibrosis, business.industry, medicine.disease, Fibrosis, Lung fibrosis, business
Abstract

ObjectiveTo assess the safety and efficacy of rituximab in systemic sclerosis (SSc) in clinical practice.MethodsWe performed a prospective study including patients with SSc from the European Scleroderma Trials and Research (EUSTAR) network treated with rituximab and matched with untreated patients with SSc. The main outcomes measures were adverse events, skin fibrosis improvement, lung fibrosis worsening and steroids use among propensity score-matched patients treated or not with rituximab.Results254 patients were treated with rituximab, in 58% for lung and in 32% for skin involvement. After a median follow-up of 2 years, about 70% of the patients had no side effect. Comparison of treated patients with 9575 propensity-score matched patients showed that patients treated with rituximab were more likely to have skin fibrosis improvement (22.7 vs 14.03 events per 100 person-years; OR: 2.79 [1.47–5.32]; p=0.002). Treated patients did not have significantly different rates of decrease in forced vital capacity (FVC)>10% (OR: 1.03 [0.55–1.94]; p=0.93) nor in carbon monoxide diffusing capacity (DLCO) decrease. Patients having received rituximab were more prone to stop or decrease steroids (OR: 2.34 [1.56–3.53], pConclusionRituximab use was associated with a good safety profile in this large SSc-cohort. Significant change was observed on skin fibrosis, but not on lung. However, the limitation is the observational design. The potential stabilisation of lung fibrosis by rituximab has to be addressed by a randomised trial.

Published
2019

45. Two Single-Nucleotide Polymorphisms in the 5′ and 3′ Ends of the Osteopontin Gene Contribute to Susceptibility to Systemic Lupus Erythematosus

Author

DʼAlfonso, S., Barizzone, N., Giordano, M., Chiocchetti, A., Magnani, C., Castelli, L., Indelicato, M., Giacopelli, F., Marchini, M., Scorza, R., Danieli, M. G., Cappelli, M., Migliaresi, S., Bigliardo, B., Sabbadini, M. G., Baldissera, E., Galeazzi, M., Sebastiani, G. D., Minisola, G., Ravazzolo, R., Dianzani, U., and Momigliano-Richiardi, P.

Published
2005

49. Clinical and serological associations of ribosomal P autoantibodies in systemic lupus erythematosus: prospective evaluation in a large cohort of Italian patients

Author

Gerli, R., Caponi, L., Tincani, A., Scorza, R., Sabbadini, M. G., Danieli, M. G., De Angelis, V., Cesarotti, M., Piccirilli, M., Quartesan, R., Moretti, P., Cantoni, C., Franceschini, F., Cavazzana, I., Origgi, L., Vanoli, M., Bozzolo, E., Ferrario, L., Padovani, A., Gambini, O., Vanzulli, L., Croce, D., and Bombardieri, S.

Published
2002

Catalog

Books, media, physical & digital resources
See catalog results