Search

Your search keyword '"Sciannamea, Ivano"' showing total 17 results
Start Over Author "Sciannamea, Ivano"
17 results on '"Sciannamea, Ivano"'

1. Laparoscopic versus open resection for hepatocellular carcinoma according to the procedure’s complexity: real-world weighted data from a national register

Author

Corleone, PioS., Ciulli, Cristina, Bernasconi, Davide, Donadon, Matteo, Procopio, Fabio, Razionale, Francesco, Ratti, Francesca, Romano, Pierluigi, De Carlis, Riccardo, Russolillo, Nadia, Marinelli, Laura, Iaria, Maurizio, De Stefano, Francesca, Scarinci, Andrea, Laureiro, Zoe L., Scotti, Mauro, Marchitelli, Ivan, Rompianesi, Gianluca, Cucchetti, Alessandro, Franceschi, Angelo, Casella, Annachiara, Cosola, Davide, Patrizia, Pelizzo, Notte, Francesca, Patrone, Renato, Manzoni, Alberto, Sciannamea, Ivano, Malagnino, Alessia, Cammarata, Francesco, Mantovani, Guido, Famularo, Simone, Milana, Flavio, Ardito, Francesco, Cipriani, Federica, Vitale, Alessandro, Lauterio, Andrea, Serenari, Matteo, Fontana, Andrea, Nicolini, Daniele, Giuffrida, Mario, Garancini, Mattia, Dominioni, Tommaso, Zanello, Matteo, Perri, Pasquale, Lai, Quirino, Conci, Simone, Molfino, Sarah, Giglio, Mariano, LaBarba, Giuliano, Ferrari, Cecilia, Conticchio, Maria, Germani, Paola, Romano, Maurizio, Patauner, Stefan, Belli, Andrea, Zimmitti, Giuseppe, Antonucci, Adelmo, Fumagalli, Luca, Troci, Albert, De Angelis, Michela, Boccia, Luigi, Crespi, Michele, Hilal, Moh’d A., Izzo, Francesco, Frena, Antonio, Zanus, Giacomo, Tarchi, Paola, Memeo, Riccardo, Griseri, Guido, Ercolani, Giorgio, Troisi, Roberto, Baiocchi, Gian L., Ruzzenente, Andrea, Rossi, Massimo, Grazi, Gian L., Jovine, Elio, Maestri, Marcello, Romano, Fabrizio, Valle, Raffaele D., Vivarelli, Marco, Ferrero, Alessandro, Cescon, Matteo, De Carlis, Luciano, Cillo, Umberto, Aldrighetti, Luca, Giuliante, Felice, and Torzilli, Guido

Published
2024
Full Text
View/download PDF

2. The largest western experience on salvage hepatectomy for recurrent hepatocellular carcinoma: propensity score-matched analysis on behalf of He.RC.O.Le.Study Group

Author

Giuffrida, Mario, Russolillo, Nadia, Razionale, Francesco, De Peppo, Valerio, Tomasoni, Matteo, Marchitelli, Ivan, Costa, Guido, Laureiro, Zoe L., Scotti, Mauro, Calcagno, Pietro, Cosola, Davide, Franceschi, Angelo, Manzoni, Alberto, Pennacchi, Luca, Montuori, Mauro, Conticchio, Maria, Ratti, Francesca, Notte, Francesca, Cucchetti, Alessandro, Salvador, Luca, Corleone, Pio, Garancini, Mattia, Ciulli, Cristina, Iaria, Maurizio, Bianchi, Giorgio, Fazio, Federico, Ardito, Francesco, Perri, Pasquale, Pontarolo, Nicholas, Conci, Simone, Donadon, Matteo, Zanello, Matteo, Lai, Quirino, Famularo, Simone, Molfino, Sarah, Sciannamea, Ivano, Fumagalli, Luca, Germani, Paola, Floridi, Antonio, Ferrari, Cecilia, Zimmitti, Giuseppe, Troci, Albert, Zago, Mauro, Ferraro, Valentina, Cipriani, Federica, Patauner, Stefan, La Barba, Giuliano, Romano, Maurizio, Zanus, Giacomo, Ercolani, Giorgio, Frena, Antonio, Aldrighetti, Luca, Memeo, Riccardo, Pinotti, Enrico, Crespi, Michele, Hilal, Moh'd Abu, Griseri, Guido, Tarchi, Paola, Chiarelli, Marco, Antonucci, Adelmo, Baiocchi, Gian L., Romano, Fabrizio, Rossi, Massimo, Jovine, Elio, Torzilli, Guido, Ruzzenente, Andrea, Maestri, Marcello, Grazi, Gian L., Giuliante, Felice, Ferrero, Alessandro, and Dalla Valle, Raffaele

Published
2022
Full Text
View/download PDF

3. The Impact of Postoperative Ascites on Survival After Surgery for Hepatocellular Carcinoma: a National Study

Author

Famularo, Simone, Donadon, Matteo, Cipriani, Federica, Ardito, Francesco, Iaria, Maurizio, Carissimi, Francesca, Perri, Pasquale, Dominioni, Tommaso, Zanello, Matteo, Conci, Simone, Molfino, Sarah, D’Acapito, Fabrizio, Germani, Paola, Ferrari, Cecilia, Patauner, Stefan, Pinotti, Enrico, Sciannamea, Ivano, Garatti, Marco, Lodo, Enrico, Troci, Albert, Delvecchio, Antonella, Floridi, Antonio, Bernasconi, Davide Paolo, Fumagalli, Luca, Chiarelli, Marco, Memeo, Riccardo, Crespi, Michele, Zanus, Giacomo, Zimmitti, Giuseppe, Antonucci, Adelmo, Zago, Mauro, Frena, Antonio, Griseri, Guido, Tarchi, Paola, Ercolani, Giorgio, Baiocchi, Gian Luca, Ruzzenente, Andrea, Jovine, Elio, Maestri, Marcello, Grazi, GianLuca, Valle, Raffaele Dalla, Giuliante, Felice, Aldrighetti, Luca, Romano, Fabrizio, Torzilli, Guido, Costa, Guido, Ciulli, Cristina, Giani, Alessandro, Ratti, Francesca, Bellobono, Manuela, Cremaschi, Elena, Valsecchi, Maria Grazia, De Peppo, Valerio, Calabrese, Francesco, DeSario, Giuseppina, Lazzari, Giovanni, Cucchetti, Alessandro, Cosola, Davide, Percivale, Andrea, Ciola, Michele, Montuori, Mauro, Frassani, Silvia, Manzoni, Alberto, Salvador, Luca, Pennacchi, Luca, Corleone, Pio, and Conticchio, Maria

Published
2021
Full Text
View/download PDF

4. Curative versus palliative treatments for recurrent hepatocellular carcinoma: a multicentric weighted comparison

Author

Ciulli, Cristina, Giani, Alessandro, Carissimi, Francesca, Costa, Guido, Ratti, Francesca, Cucchetti, Alessandro, Calabrese, Francesco, Cremaschi, Elena, Lazzari, Giovanni, Franceschi, Angelo, Sega, Valentina, Conticchio, Maria, Pennacchi, Luca, Ciola, Michele, Sciannamea, Ivano, De Peppo, Valerio, Famularo, Simone, Donadon, Matteo, Cipriani, Federica, Bernasconi, Davide P., LaBarba, Giuliano, Dominioni, Tommaso, Iaria, Maurizio, Molfino, Sarah, Conci, Simone, Ferrari, Cecilia, Garatti, Marco, Delvecchio, Antonella, Troci, Albert, Patauner, Stefan, Frassani, Silvia, Cosimelli, Maurizio, Zanus, Giacomo, Giuliante, Felice, Jovine, Elio, Valsecchi, Maria G., Grazi, GianLuca, Antonucci, Adelmo, Frena, Antonio, Crespi, Michele, Memeo, Riccardo, Zimmitti, Giuseppe, Griseri, Guido, Ruzzenente, Andrea, Baiocchi, Gianluca, DallaValle, Raffaele, Maestri, Marcello, Ercolani, Giorgio, Aldrighetti, Luca, Torzilli, Guido, and Romano, Fabrizio

Published
2021
Full Text
View/download PDF

5. Hepatocellular carcinoma surgical and oncological trends in a national multicentric population: the HERCOLES experience

Author

Famularo, Simone, Donadon, Matteo, Cipriani, Federica, Ardito, Francesco, Carissimi, Francesca, Perri, Pasquale, Iaria, Maurizio, Dominioni, Tommaso, Zanello, Matteo, Conci, Simone, Molfino, Sarah, LaBarba, Giuliano, Ferrari, Cecilia, Germani, Paola, Patauner, Stefan, Pinotti, Enrico, Lodo, Enrico, Garatti, Marco, Sciannamea, Ivano, Troci, Albert, Conticchio, Maria, Floridi, Antonio, Chiarelli, Marco, Fumagalli, Luca, Memeo, Riccardo, Crespi, Michele, Antonucci, Adelmo, Zimmitti, Giuseppe, Zanus, Giacomo, Zago, Mauro, Frena, Antonio, Tarchi, Paola, Griseri, Guido, Ercolani, Giorgio, Baiocchi, Gian Luca, Ruzzenente, Andrea, Jovine, Elio, Maestri, Marcello, DallaValle, Raffaele, Grazi, Gian Luca, Giuliante, Felice, Aldrighetti, Luca, Torzilli, Guido, and Romano, Fabrizio

Published
2020
Full Text
View/download PDF

7. Single Large Hepatocellular Carcinoma > 5 cm with Surgical Indication: Is it Mandatory a Major Hepatectomy? A Propensity-score Weighted Analysis

Author

Garancini, M., primary, Ferrero, A., additional, De Carlis, L., additional, Grazi, G.L., additional, Giuliante, F., additional, Cillo, U., additional, Cescon, M., additional, Valle, R. Dalla, additional, Vivarelli, M., additional, Torzilli, G., additional, Aldrighetti, L., additional, Romano, Fabrizio, additional, Donadon, Matteo, additional, Cipriani, Federica, additional, Serenari, Matteo, additional, Ardito, Francesco, additional, Lauterio, Andrea, additional, Vitale, Alessandro, additional, Fazio, Federico, additional, Nicolini, Daniele, additional, Perri, Pasquale, additional, Iaria, Giuseppe, additional, Famularo, Simone, additional, Dominioni, Tommaso, additional, Zanello, Matteo, additional, Lai, Quirino, additional, Conci, Simone, additional, Molfino, Sarah, additional, Ferrari, Cecilia, additional, Germani, Paola, additional, Scotti, Mauro Alessandro, additional, Zago, Mauro, additional, Zimmitti, Giuseppe, additional, La Barba Maurizio Romano, Giuliano, additional, Sciannamea, Ivano, additional, Fumagalli, Luca, additional, Troci, Albert, additional, Ferraro, Valentina, additional, Memeo, Riccardo, additional, Crespi, Michele, additional, Chiarelli, Marco, additional, Antonucci, Adelmo, additional, Zanus, Giacomo, additional, Ercolani, Giorgio, additional, Hilal, Moh’d Abu, additional, Pinotti, Enrico, additional, Tarchi, Paola, additional, Griseri, Guido, additional, Baiocchi, Gian Luca, additional, Ruzzenente, Andrea, additional, Rossi, Massimo, additional, Jovine, Elio, additional, and Maestri, Marcello, additional

Published
2023
Full Text
View/download PDF

8. Hepatocellular carcinoma surgical and oncological trends in a national multicentric population: the HERCOLES experience

Author

Famularo, Simone, Donadon, Matteo, Cipriani, Federica, Ardito, Francesco, Carissimi, Francesca, Perri, Pasquale, Iaria, Maurizio, Dominioni, Tommaso, Zanello, Matteo, Conci, Simone, Molfino, Sarah, LaBarba, Giuliano, Ferrari, Cecilia, Germani, Paola, Patauner, Stefan, Pinotti, Enrico, Lodo, Enrico, Garatti, Marco, Sciannamea, Ivano, Troci, Albert, Conticchio, Maria, Floridi, Antonio, Chiarelli, Marco, Fumagalli, Luca, Memeo, Riccardo, Crespi, Michele, Antonucci, Adelmo, Zimmitti, Giuseppe, Zanus, Giacomo, Zago, Mauro, Frena, Antonio, Tarchi, Paola, Griseri, Guido, Ercolani, Giorgio, Baiocchi, Gian Luca, Ruzzenente, Andrea, Jovine, Elio, Maestri, Marcello, DallaValle, Raffaele, Grazi, Gian Luca, Giuliante, Felice, Aldrighetti, Luca, Torzilli, Guido, and Romano, Fabrizio

Abstract

Liver surgery is the first line treatment for hepatocarcinoma. Hepatocarcinoma Recurrence on the Liver Study (HERCOLES) Group was established in 2018 with the goal to create a network of Italian centres sharing data and promoting scientific research on hepatocellular carcinoma (HCC) in the surgical field. This is the first national report that analyses the trends in surgical and oncological outcomes. Register data were collected by 22 Italian centres between 2008 and 2018. One hundred sixty-four variables were collected, regarding liver functional status, tumour burden, radiological, intraoperative and perioperative data, histological features and oncological follow-up. 2381 Patients were enrolled. Median age was 70 (IQR 63–75) years old. Cirrhosis was present in 1491 patients (62.6%), and Child-A were 89.9% of cases. HCC was staged as BCLC0-A in almost 50% of cases, while BCLC B and C were 20.7% and 17.9% respectively. Major liver resections were 481 (20.2%), and laparoscopy was employed in 753 (31.6%) cases. Severe complications occurred only in 5%. Postoperative ascites was recorded in 10.5% of patients, while posthepatectomy liver failure was observed in 4.9%. Ninety-day mortality was 2.5%. At 5 years, overall survival was 66.1% and disease-free survival was 40.9%. Recurrence was intrahepatic in 74.6% of cases. Redo-surgery and thermoablation for recurrence were performed up to 32% of cases. This is the most updated Italian report of the national experience in surgical treatment for HCC. This dataset is consistently allowing the participating centres in creating multicentric analysis which are already running with a very large sample size and strong power.

Published
2024
Full Text
View/download PDF

9. The largest western experience on salvage hepatectomy for recurrent hepatocellular carcinoma: propensity score-matched analysis on behalf of He.RC.O.Le.Study Group

Author

Iaria, Maurizio, primary, Bianchi, Giorgio, additional, Fazio, Federico, additional, Ardito, Francesco, additional, Perri, Pasquale, additional, Pontarolo, Nicholas, additional, Conci, Simone, additional, Donadon, Matteo, additional, Zanello, Matteo, additional, Lai, Quirino, additional, Famularo, Simone, additional, Molfino, Sarah, additional, Sciannamea, Ivano, additional, Fumagalli, Luca, additional, Germani, Paola, additional, Floridi, Antonio, additional, Ferrari, Cecilia, additional, Zimmitti, Giuseppe, additional, Troci, Albert, additional, Zago, Mauro, additional, Ferraro, Valentina, additional, Cipriani, Federica, additional, Patauner, Stefan, additional, La Barba, Giuliano, additional, Romano, Maurizio, additional, Zanus, Giacomo, additional, Ercolani, Giorgio, additional, Frena, Antonio, additional, Aldrighetti, Luca, additional, Memeo, Riccardo, additional, Pinotti, Enrico, additional, Crespi, Michele, additional, Hilal, Moh'd Abu, additional, Griseri, Guido, additional, Tarchi, Paola, additional, Chiarelli, Marco, additional, Antonucci, Adelmo, additional, Baiocchi, Gian L., additional, Romano, Fabrizio, additional, Rossi, Massimo, additional, Jovine, Elio, additional, Torzilli, Guido, additional, Ruzzenente, Andrea, additional, Maestri, Marcello, additional, Grazi, Gian L., additional, Giuliante, Felice, additional, Ferrero, Alessandro, additional, Dalla Valle, Raffaele, additional, Giuffrida, Mario, additional, Russolillo, Nadia, additional, Razionale, Francesco, additional, De Peppo, Valerio, additional, Tomasoni, Matteo, additional, Marchitelli, Ivan, additional, Costa, Guido, additional, Laureiro, Zoe L., additional, Scotti, Mauro, additional, Calcagno, Pietro, additional, Cosola, Davide, additional, Franceschi, Angelo, additional, Manzoni, Alberto, additional, Pennacchi, Luca, additional, Montuori, Mauro, additional, Conticchio, Maria, additional, Ratti, Francesca, additional, Notte, Francesca, additional, Cucchetti, Alessandro, additional, Salvador, Luca, additional, Corleone, Pio, additional, Garancini, Mattia, additional, and Ciulli, Cristina, additional

Published
2022
Full Text
View/download PDF

10. Hepatectomy for Metabolic Associated Fatty Liver Disease (MAFLD) related HCC: Propensity case-matched analysis with viral- and alcohol-related HCC

Author

Conci, Simone, primary, Cipriani, Federica, additional, Donadon, Matteo, additional, Marchitelli, Ivan, additional, Ardito, Francesco, additional, Famularo, Simone, additional, Perri, Pasquale, additional, Iaria, Maurizio, additional, Ansaloni, Luca, additional, Zanello, Matteo, additional, La Barba, Giuliano, additional, Patauner, Stefan, additional, Pinotti, Enrico, additional, Molfino, Sarah, additional, Germani, Paola, additional, Romano, Maurizio, additional, Sciannamea, Ivano, additional, Ferrari, Cecilia, additional, Manzoni, Alberto, additional, Troci, Albert, additional, Fumagalli, Luca, additional, Delvecchio, Antonella, additional, Floridi, Antonio, additional, Memeo, Riccardo, additional, Chiarelli, Marco, additional, Crespi, Michele, additional, Zimmitti, Giuseppe, additional, Griseri, Guido, additional, Antonucci, Adelmo, additional, Zanus, Giacomo, additional, Tarchi, Paola, additional, Baiocchi, Gian Luca, additional, Zago, Mauro, additional, Frena, Antonio, additional, Ercolani, Giorgio, additional, Jovine, Elio, additional, Maestri, Marcello, additional, Valle, Raffaele Dalla, additional, Grazi, Gian Luca, additional, Romano, Fabrizio, additional, Giuliante, Felice, additional, Torzilli, Guido, additional, Aldrighetti, Luca, additional, and Ruzzenente, Andrea, additional

Published
2022
Full Text
View/download PDF

11. Additional file 1 of Indications and outcomes of enterovesical and colovesical fistulas: systematic review of the literature and meta-analysis of prevalence

Author

Granieri, Stefano, Sessa, Francesco, Bonomi, Alessandro, Paleino, Sissi, Bruno, Federica, Chierici, Andrea, Sciannamea, Ivano Massimiliano, Germini, Alessandro, Campi, Riccardo, Talso, Michele, Facciorusso, Antonio, Deiana, Gianfranco, Serni, Sergio, and Cotsoglou, Christian

Abstract

Additional file 1. Supplemetary materials including diagnostic methods, results of sensitivity analysis, funnel plots and P-curve analysis for complications and postoperative mortality, bubble plot of metaregression, word combination syntax.

Published
2021
Full Text
View/download PDF

12. Curative versus palliative treatments for recurrent hepatocellular carcinoma: a multicentric weighted comparison

Author

Famularo, Simone, primary, Donadon, Matteo, additional, Cipriani, Federica, additional, Bernasconi, Davide P., additional, LaBarba, Giuliano, additional, Dominioni, Tommaso, additional, Iaria, Maurizio, additional, Molfino, Sarah, additional, Conci, Simone, additional, Ferrari, Cecilia, additional, Garatti, Marco, additional, Delvecchio, Antonella, additional, Troci, Albert, additional, Patauner, Stefan, additional, Frassani, Silvia, additional, Cosimelli, Maurizio, additional, Zanus, Giacomo, additional, Giuliante, Felice, additional, Jovine, Elio, additional, Valsecchi, Maria G., additional, Grazi, GianLuca, additional, Antonucci, Adelmo, additional, Frena, Antonio, additional, Crespi, Michele, additional, Memeo, Riccardo, additional, Zimmitti, Giuseppe, additional, Griseri, Guido, additional, Ruzzenente, Andrea, additional, Baiocchi, Gianluca, additional, DallaValle, Raffaele, additional, Maestri, Marcello, additional, Ercolani, Giorgio, additional, Aldrighetti, Luca, additional, Torzilli, Guido, additional, Romano, Fabrizio, additional, Ciulli, Cristina, additional, Giani, Alessandro, additional, Carissimi, Francesca, additional, Costa, Guido, additional, Ratti, Francesca, additional, Cucchetti, Alessandro, additional, Calabrese, Francesco, additional, Cremaschi, Elena, additional, Lazzari, Giovanni, additional, Franceschi, Angelo, additional, Sega, Valentina, additional, Conticchio, Maria, additional, Pennacchi, Luca, additional, Ciola, Michele, additional, Sciannamea, Ivano, additional, and De Peppo, Valerio, additional

Published
2021
Full Text
View/download PDF

13. Performance of Comprehensive Complication Index and Clavien-Dindo Complication Scoring System in Liver Surgery for Hepatocellular Carcinoma

Author

Giani, Alessandro, primary, Cipriani, Federica, additional, Famularo, Simone, additional, Donadon, Matteo, additional, Bernasconi, Davide Paolo, additional, Ardito, Francesco, additional, Fazio, Federico, additional, Nicolini, Daniele, additional, Perri, Pasquale, additional, Giuffrida, Mario, additional, Pontarolo, Nicholas, additional, Zanello, Matteo, additional, Lai, Quirino, additional, Conci, Simone, additional, Molfino, Sarah, additional, Germani, Paola, additional, Pinotti, Enrico, additional, Romano, Maurizio, additional, La Barba, Giuliano, additional, Ferrari, Cecilia, additional, Patauner, Stefan, additional, Manzoni, Alberto, additional, Sciannamea, Ivano, additional, Fumagalli, Luca, additional, Troci, Albert, additional, Ferraro, Valentina, additional, Floridi, Antonio, additional, Romano, Fabrizio, additional, Ciulli, Cristina, additional, Braga, Marco, additional, Ratti, Francesca, additional, Costa, Guido, additional, Razionale, Francesco, additional, Russolillo, Nadia, additional, Marinelli, Laura, additional, De Peppo, Valerio, additional, Cremaschi, Elena, additional, Calabrese, Francesco, additional, Larghi Laureiro, Zoe, additional, Lazzari, Giovanni, additional, Cosola, Davide, additional, Montuori, Mauro, additional, Salvador, Luca, additional, Cucchetti, Alessandro, additional, Franceschi, Angelo, additional, Ciola, Michele, additional, Sega, Valentina, additional, Calcagno, Pietro, additional, Pennacchi, Luca, additional, Tedeschi, Michele, additional, Memeo, Riccardo, additional, Crespi, Michele, additional, Chiarelli, Marco, additional, Antonucci, Adelmo, additional, Zimmitti, Giuseppe, additional, Frena, Antonio, additional, Percivale, Andrea, additional, Ercolani, Giorgio, additional, Zanus, Giacomo, additional, Zago, Mauro, additional, Tarchi, Paola, additional, Baiocchi, Gian Luca, additional, Ruzzenente, Andrea, additional, Rossi, Massimo, additional, Jovine, Elio, additional, Maestri, Marcello, additional, Dalla Valle, Raffaele, additional, Grazi, Gian Luca, additional, Vivarelli, Marco, additional, Ferrero, Alessandro, additional, Giuliante, Felice, additional, Torzilli, Guido, additional, Aldrighetti, Luca, additional, and Gianotti, Luca, additional

Published
2020
Full Text
View/download PDF

14. Single Large Hepatocellular Carcinoma > 5 cm with Surgical Indication: Is it Mandatory a Major Hepatectomy? A Propensity-score Weighted Analysis

Author

Romano, Fabrizio, Donadon, Matteo, Cipriani, Federica, Serenari, Matteo, Ardito, Francesco, Lauterio, Andrea, Vitale, Alessandro, Fazio, Federico, Nicolini, Daniele, Perri, Pasquale, Iaria, Giuseppe, Famularo, Simone, Dominioni, Tommaso, Zanello, Matteo, Lai, Quirino, Conci, Simone, Molfino, Sarah, Ferrari, Cecilia, Germani, Paola, Scotti, Mauro Alessandro, Zago, Mauro, Zimmitti, Giuseppe, La Barba Maurizio Romano, Giuliano, Sciannamea, Ivano, Fumagalli, Luca, Troci, Albert, Ferraro, Valentina, Memeo, Riccardo, Crespi, Michele, Chiarelli, Marco, Antonucci, Adelmo, Zanus, Giacomo, Ercolani, Giorgio, Hilal, Moh’d Abu, Pinotti, Enrico, Tarchi, Paola, Griseri, Guido, Baiocchi, Gian Luca, Ruzzenente, Andrea, Rossi, Massimo, Jovine, Elio, Maestri, Marcello, Garancini, M., Ferrero, A., De Carlis, L., Grazi, G.L., Giuliante, F., Cillo, U., Cescon, M., Valle, R. Dalla, Vivarelli, M., Torzilli, G., and Aldrighetti, L.

Published
2023
Full Text
View/download PDF

15. Hepatocellular carcinoma surgical and oncological trends in a national multicentric population: the HERCOLES experience

Author

Famularo, S., Donadon, M., Cipriani, Fabrizio, Ardito, Francesco, Carissimi, F., Perri, Pierluigi, Iaria, M., Dominioni, T., Zanello, M., Conci, S., Molfino, S., Labarba, G., Ferrari, C., Germani, P., Patauner, S., Pinotti, E., Lodo, E., Garatti, M., Sciannamea, I., Troci, A., Conticchio, M., Floridi, A., Chiarelli, M., Fumagalli, L., Memeo, R., Crespi, M., Antonucci, Anna Maria, Zimmitti, Giuseppe, Zanus, G., Zago, M., Frena, A., Tarchi, P., Griseri, G., Ercolani, G., Baiocchi, G. L., Ruzzenente, A., Jovine, E., Maestri, Marta, Dallavalle, R., Grazi, G. L., Giuliante, Felice, Aldrighetti, L., Torzilli, Guido, Romano, Federica, Bernasconi, D. P., Ciulli, C., Giani, A., Costa, G., Ratti, F., Bellobono, M., Calabrese, F., Cremaschi, E., De Peppo, V., Cucchetti, A., Lazzari, Giovanni, Percivale, A., Ciola, M., Sega, V., Frassani, S., Del Vecchio, Arianna, Pennacchi, L., Corleone, P., Cosola, D., Salvador, L., Montuori, M., Famularo, Simone, Donadon, Matteo, Cipriani, Federica, Ardito, Francesco, Carissimi, Francesca, Perri, Pasquale, Iaria, Maurizio, Dominioni, Tommaso, Zanello, Matteo, Conci, Simone, Molfino, Sarah, LaBarba, Giuliano, Ferrari, Cecilia, Germani, Paola, Patauner, Stefan, Pinotti, Enrico, Lodo, Enrico, Garatti, Marco, Sciannamea, Ivano, Troci, Albert, Conticchio, Maria, Floridi, Antonio, Chiarelli, Marco, Fumagalli, Luca, Memeo, Riccardo, Crespi, Michele, Antonucci, Adelmo, Zimmitti, Giuseppe, Zanus, Giacomo, Zago, Mauro, Frena, Antonio, Tarchi, Paola, Griseri, Guido, Ercolani, Giorgio, Baiocchi, Gian Luca, Ruzzenente, Andrea, Jovine, Elio, Maestri, Marcello, DallaValle, Raffaele, Grazi, Gian Luca, Giuliante, Felice, Aldrighetti, Luca, Torzilli, Guido, Romano, Fabrizio, Famularo, S., Donadon, M., Cipriani, F., Ardito, F., Carissimi, F., Perri, P., Iaria, M., Dominioni, T., Zanello, M., Conci, S., Molfino, S., Labarba, G., Ferrari, C., Germani, P., Patauner, S., Pinotti, E., Lodo, E., Garatti, M., Sciannamea, I., Troci, A., Conticchio, M., Floridi, A., Chiarelli, M., Fumagalli, L., Memeo, R., Crespi, M., Antonucci, A., Zimmitti, G., Zanus, G., Zago, M., Frena, A., Tarchi, P., Griseri, G., Ercolani, G., Baiocchi, G. L., Ruzzenente, A., Jovine, E., Maestri, M., Dallavalle, R., Grazi, G. L., Giuliante, F., Aldrighetti, L., Torzilli, G., Romano, F., Bernasconi, D. P., Ciulli, C., Giani, A., Costa, G., Ratti, F., Bellobono, M., Calabrese, F., Cremaschi, E., De Peppo, V., Cucchetti, A., Lazzari, G., Percivale, A., Ciola, M., Sega, V., Frassani, S., Del Vecchio, A., Pennacchi, L., Corleone, P., Cosola, D., Salvador, L., and Montuori, M.

Subjects
Male, Cirrhosis, Outcome Assessment, Hepatocellular carcinoma, Settore MED/18 - CHIRURGIA GENERALE, Datasets as Topic, HERCOLES, Hepatocarcinoma recurrence, Liver surgery, Redo surgery, Outcome Assessment, Health Care, Ascites, Registries, Laparoscopy, education.field_of_study, medicine.diagnostic_test, Liver Neoplasms, Middle Aged, Italy, Local, Radiological weapon, Female, medicine.symptom, Reoperation, medicine.medical_specialty, Carcinoma, Hepatocellular, Population, NO, Internal medicine, medicine, Hepatectomy, Humans, education, LS7_4, Aged, business.industry, Carcinoma, Hepatocellular, Perioperative, Hepatology, medicine.disease, Surgery, Health Care, Neoplasm Recurrence, Neoplasm Recurrence, Local, business
Abstract

Liver surgery is the first line treatment for hepatocarcinoma. Hepatocarcinoma Recurrence on the Liver Study (HERCOLES) Group was established in 2018 with the goal to create a network of Italian centres sharing data and promoting scientific research on hepatocellular carcinoma (HCC) in the surgical field. This is the first national report that analyses the trends in surgical and oncological outcomes. Register data were collected by 22 Italian centres between 2008 and 2018. One hundred sixty-four variables were collected, regarding liver functional status, tumour burden, radiological, intraoperative and perioperative data, histological features and oncological follow-up. 2381 Patients were enrolled. Median age was 70 (IQR 63-75) years old. Cirrhosis was present in 1491 patients (62.6%), and Child-A were 89.9% of cases. HCC was staged as BCLC0-A in almost 50% of cases, while BCLC B and C were 20.7% and 17.9% respectively. Major liver resections were 481 (20.2%), and laparoscopy was employed in 753 (31.6%) cases. Severe complications occurred only in 5%. Postoperative ascites was recorded in 10.5% of patients, while posthepatectomy liver failure was observed in 4.9%. Ninety-day mortality was 2.5%. At 5years, overall survival was 66.1% and disease-free survival was 40.9%. Recurrence was intrahepatic in 74.6% of cases. Redo-surgery and thermoablation for recurrence were performed up to 32% of cases. This is the most updated Italian report of the national experience in surgical treatment for HCC. This dataset is consistently allowing the participating centres in creating multicentric analysis which are already running with a very large sample size and strong power. Liver surgery is the first line treatment for hepatocarcinoma. Hepatocarcinoma Recurrence on the Liver Study (HERCOLES) Group was established in 2018 with the goal to create a network of Italian centres sharing data and promoting scientific research on hepatocellular carcinoma (HCC) in the surgical field. This is the first national report that analyses the trends in surgical and oncological outcomes. Register data were collected by 22 Italian centres between 2008 and 2018. One hundred sixty-four variables were collected, regarding liver functional status, tumour burden, radiological, intraoperative and perioperative data, histological features and oncological follow-up. 2381 Patients were enrolled. Median age was 70 (IQR 63–75) years old. Cirrhosis was present in 1491 patients (62.6%), and Child-A were 89.9% of cases. HCC was staged as BCLC0-A in almost 50% of cases, while BCLC B and C were 20.7% and 17.9% respectively. Major liver resections were 481 (20.2%), and laparoscopy was employed in 753 (31.6%) cases. Severe complications occurred only in 5%. Postoperative ascites was recorded in 10.5% of patients, while posthepatectomy liver failure was observed in 4.9%. Ninety-day mortality was 2.5%. At 5years, overall survival was 66.1% and disease-free survival was 40.9%. Recurrence was intrahepatic in 74.6% of cases. Redo-surgery and thermoablation for recurrence were performed up to 32% of cases. This is the most updated Italian report of the national experience in surgical treatment for HCC. This dataset is consistently allowing the participating centres in creating multicentric analysis which are already running with a very large sample size and strong power.

Published
2020

16. Single large hepatocellular carcinoma > 5 cm with surgical indication: is it mandatory a major hepatectomy? a propensity-score weighted analysis.

Author

Garancini M, Serenari M, Famularo S, Cipriani F, Ardito F, Russolillo N, Conci S, Nicolini D, Perri P, Zanello M, Iaria M, Lai Q, Romano M, La Barba G, Molfino S, Germani P, Dominioni T, Zimmiti G, Conticchio M, Fumagalli L, Zago M, Troci A, Sciannamea I, Ferrari C, Scotti MA, Griseri G, Antonucci A, Crespi M, Pinotti E, Chiarelli M, Memeo R, Hilal MA, Maestri M, Tarchi P, Baiocchi G, Ercolani G, Zanus G, Rossi M, Valle RD, Jovine E, Frena A, Patauner S, Grazi GL, Vivarelli M, Ruzzenente A, Ferrero A, Giuliante F, Aldrighetti L, Torzilli G, Cescon M, Bernasconi D, and Romano F

Subjects
Humans, Male, Female, Retrospective Studies, Middle Aged, Aged, Postoperative Complications etiology, Treatment Outcome, Survival Rate, Adult, Hepatectomy methods, Carcinoma, Hepatocellular surgery, Carcinoma, Hepatocellular pathology, Carcinoma, Hepatocellular mortality, Liver Neoplasms surgery, Liver Neoplasms pathology, Liver Neoplasms mortality, Propensity Score
Abstract

Purpose: Single large hepatocellular carcinoma >5cm (SLHCC) traditionally requires a major liver resection. Minor resections are often performed with the goal to reduce morbidity and mortality. Aim of the study was to establish if a major resection should be considered the best treatment for SLHCC or a more limited resection should be preferred., Methods: A multicenter retrospective analysis of the HE.RC.O.LE.S. Group register was performed. All collected patients with surgically treated SLHCC were divided in 5 groups of treatment (major hepatectomy, sectorectomy, left lateral sectionectomy, segmentectomy, non-anatomical resection) and compared for baseline characteristics, short and long-term results. A propensity-score weighted analysis was performed., Results: 535 patients were enrolled in the study. Major resection was associated with significantly increased major complications compared to left lateral sectionanectomy, segmentectomy and non-anatomical resection (all p<0.05) and borderline significant increased major complications compared to sectorectomy (p=0.08). Left lateral sectionectomy showed better overall survival compared to major resection (p=0.02), while other groups of treatment resulted similar to major hepatectomy group for the same item. Absence of oncological benefit after major resection and similar outcomes among the 5 groups of treatment was confirmed even in the sub-population excluding patients with macrovascular invasion., Conclusion: Major resection was associated to increased major post-operative morbidity without long-term survival benefit; when technically feasible and oncologically adequate, minor resections should be preferred for the surgical treatment of SLHCC., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Published
2024
Full Text
View/download PDF

17. [Intestinal neuroendocrine tumor. Case report and review of the literature].

Author

Micheletto G, Sciannamea I, Zanoni A, Panizzo V, Rubino B, and Danelli P

Subjects
Aged, Follow-Up Studies, Humans, Laparotomy, Lymphatic Metastasis, Male, Radiography, Abdominal, Time Factors, Tomography, X-Ray Computed, Treatment Outcome, Adenoma diagnosis, Adenoma surgery, Carcinoid Tumor diagnosis, Carcinoid Tumor diagnostic imaging, Carcinoid Tumor pathology, Carcinoid Tumor surgery, Colonic Polyps diagnosis, Colonic Polyps surgery, Ileal Neoplasms diagnosis, Ileal Neoplasms diagnostic imaging, Ileal Neoplasms pathology, Ileal Neoplasms surgery, Neoplasms, Multiple Primary diagnosis, Sigmoid Neoplasms diagnosis, Sigmoid Neoplasms surgery
Abstract

Gastroenteropancreatic (GEP) neuroendocrine tumors are rare neoplasm and have proved to be slow growing malignancies which involve many organs and most frequently the gastrointestinal tract. They have a peculiary biological behaviour: most of them have endocrine function (carcinoid syndrome); many are clinically silent until late presentation. Symptoms are non specific; the most common are abdominal pain, nausea and vomiting, weight loss and gastrointestinal (GI) blood loss. Incidental carcinoid, discovered at the time of another procedure, occurred in 40% of patients, and in multiple site throughout the GI tract. Here we report a case of a 73-year-old male with an adenomatous colonic polyp, not suitable of endoscopic treatment, and a synchronous carcinoid of small intestine discovered during surgical procedure. Therefore we performed a review of literature with particular attention to diagnosis and strategy of the treatment.

Published
2009

Catalog

Books, media, physical & digital resources
See catalog results