1,267 results on '"Schwartz, Thue W"'
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2. Multiple recent HCAR2 structures demonstrate a highly dynamic ligand binding and G protein activation mode
3. An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake
4. Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
5. Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91
6. Deciphering specificity and cross-reactivity in tachykinin NK1 and NK2 receptors
7. Microbiome-derived ethanol in nonalcoholic fatty liver disease
8. A systems biology approach to study non-alcoholic fatty liver (NAFL) in women with obesity
9. Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells
10. N -acyl taurines are endogenous lipid messengers that improve glucose homeostasis
11. G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice
12. snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis
13. Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
14. Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production
15. The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones
16. Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2
17. Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine
18. Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
19. Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolites
20. The HETE Is on FFAR1 and Pancreatic Islet Cells
21. Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
22. A new paradigm of intracrine free fatty acid receptor 4 signaling at lipid droplets
23. GPCR-Mediated Signaling of Metabolites
24. EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia–like B-cell malignancies
25. Conversion of Agonist Site to Metal-Ion Chelator Site in the β 2-Adrenergic Receptor
26. The CCR5 Receptor Acts as an Alloantigen in CCR5Δ 32 Homozygous Individuals: Identification of Chemokine-and HIV-1-Blocking Human Antibodies
27. Phorbol Esters and SDF-1 Induce Rapid Endocytosis and down Modulation of the Chemokine Receptor CXCR4
28. A Broad-Spectrum Chemokine Antagonist Encoded by Kaposi's Sarcoma- Associated Herpesvirus
29. Paracrine relationship between incretin hormones and endogenous 5‐hydroxytryptamine in the small and large intestine
30. Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk
31. Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery
32. Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle
33. Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist
34. Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery
35. Paracrine relationship between incretin hormones and endogenous 5-hydroxytryptamine in the small and large intestine
36. Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle
37. G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice
38. Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography
39. Molecular Dynamics Based Identification of Binding Pathways and Two Distinct High-Affinity Sites for Succinate in SUCNR1/GPR91
40. GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo
41. Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action
42. The Melanocortin-4 Receptor Is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-like Peptide 1 In Vivo
43. Metabolite G-protein coupled receptor signaling: Potential regulation of eicosanoids
44. Outrunning obesity with Lac-Phe?
45. Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
46. Enteroendocrine cell types revisited
47. Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells
48. Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts
49. Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction
50. Outrunning obesity with Lac-Phe?
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