240 results on '"Schwardt, Oliver"'
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2. Simultaneous quantification of atorvastatin, erlotinib and OSI-420 in rat serum and liver microsomes using a novel liquid chromatography-mass spectrometry method
3. Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics
4. Strengthening an Intramolecular Non‐Classical Hydrogen Bond to Get in Shape for Binding.
5. Tetra‐ and Hexavalent Siglec‐8 Ligands Modulate Immune Cell Activation
6. 158 Structure-guided design of derivatives of the complement inhibitor compstatin with improved species specificity profiles
7. 2-C-Branched mannosides as a novel family of FimH antagonists—Synthesis and biological evaluation
8. SIGLEC-4 (MAG) Antagonists: From the Natural Carbohydrate Epitope to Glycomimetics
9. A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewisx Mimetics
10. Tetra- and Hexavalent Siglec-8 Ligands Modulate Immune Cell Activation
11. Impact of OATP2B1 on Pharmacokinetics of Atorvastatin Investigated in rSlco2b1-Knockout and SLCO2B1-Knockin Rats
12. Prodruggability of carbohydrates--oral FimH antagonists
13. Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth
14. A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewis x Mimetics.
15. Front Cover: Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside (ChemMedChem 3/2022)
16. Design, synthesis and biological evaluation of mannosyl triazoles as FimH antagonists
17. Prodrugs of E‐selectin Antagonists with Enhanced Pharmacokinetic Properties
18. A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN
19. Kinetic and thermodynamic properties of MAG antagonists
20. Design, synthesis, biological evaluation, and modeling of a non-carbohydrate antagonist of the myelin-associated glycoprotein
21. Probing the carbohydrate recognition domain of E-selectin: The importance of the acid orientation in sLe x mimetics
22. Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2
23. Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside
24. Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R)
25. Therapeutic Peptides as Emerging Options to Restore Misguided Host Defence and Homeostasis: From Teaching to Concept to Clinic
26. Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2
27. Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists?
28. Trivalent, Gal/Gal NAc-containing ligands designed for the asialoglycoprotein receptor
29. A Potent Mimetic of the Siglec-8 Ligand 6'-Sulfo-Sialyl Lewisx
30. SIGLEC-4 (MAG) Antagonists: From the Natural Carbohydrate Epitope to Glycomimetics
31. Mimetics of the tri- and tetrasaccharide epitope of GQ1bα as myelin-associated glycoprotein (MAG) ligands
32. Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG)
33. Drug Discovery Today
34. Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside.
35. Antagonists of the myelin-associated glycoprotein: A new class of tetrasaccharide mimics
36. A Potent Mimetic of the Siglec‐8 Ligand 6’‐Sulfo‐Sialyl Lewisx
37. Carbohydrate Mimetics in Drug Discovery
38. Prodrugs of E‐selectin Antagonists with Enhanced Pharmacokinetic Properties.
39. Synthesis of aryl sialosides using Mitsunobu conditions
40. Comparison of affinity ranking by target-directed dynamic combinatorial chemistry and surface plasmon resonance
41. Front Cover: Improvement of Aglycone π‐Stacking Yields Nanomolar to Sub‐nanomolar FimH Antagonists (ChemMedChem 7/2019)
42. Improvement of Aglycone π‐Stacking Yields Nanomolar to Sub‐nanomolar FimH Antagonists
43. A Potent Mimetic of the Siglec‐8 Ligand 6'‐Sulfo‐Sialyl Lewisx.
44. Target‐directed Dynamic Combinatorial Chemistry: A Study on Potentials and Pitfalls as Exemplified on a Bacterial Target
45. Urinary Tract Infection: Which Conformation of the Bacterial Lectin FimH Is Therapeutically Relevant?
46. Back Cover: The Conformational Variability of FimH: Which Conformation Represents the Therapeutic Target? (ChemBioChem 11/2016)
47. The Conformational Variability of FimH: Which Conformation Represents the Therapeutic Target?
48. FimH Antagonists: Phosphate Prodrugs Improve Oral Bioavailability
49. The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X‐ray Crystallography
50. FimH Antagonists: Bioisosteres To Improve the in Vitro and in Vivo PK/PD Profile
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