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804 results on '"Schuster, Alexander K."'

20. Circulating microRNAs predict recurrence and death following venous thromboembolism

Author

ten Cate, Vincent, Rapp, Steffen, Schulz, Andreas, Pallares Robles, Alejandro, Jurk, Kerstin, Koeck, Thomas, Espinola-Klein, Christine, Halank, Michael, Seyfarth, Hans-Jürgen, Beutel, Manfred E., Schuster, Alexander K., Marini, Federico, Hobohm, Lukas, Lankeit, Mareike, Lackner, Karl J., Ruf, Wolfram, Münzel, Thomas, Andrade-Navarro, Miguel A., Prochaska, Jürgen H., Konstantinides, Stavros V., and Wild, Philipp S.

Published
2023
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24. Accuracy of IOL power calculations in the very elderly

Author

Sella, Ruti, Chou, Linda, Schuster, Alexander K, Gali, Helena E, Weinreb, Robert N, and Afshari, Natalie A

Subjects
Biomedical and Clinical Sciences, Ophthalmology and Optometry, Eye Disease and Disorders of Vision, Clinical Research, Aging, Eye, Aged, Aged, 80 and over, Biometry, Cataract Extraction, Humans, Lenses, Intraocular, Optics and Photonics, Refraction, Ocular, Retrospective Studies, Visual Acuity, Clinical Sciences, Immunology, Opthalmology and Optometry, Ophthalmology & Optometry, Ophthalmology and optometry
Abstract

Background/objectivesTo analyze the refractive predictability and outcomes of cataract surgery in the very elderly (≥85 years old).Subjects/methodsA retrospective case-series performed at the Shiley Eye Institute, University of California San Diego, USA. Electronically pulled data of 2444 surgeries revealed 147 surgeries on 133 very elderly patients. Chart review was conducted for all very elderly and corresponding control patients (75-84 years old). The first operated eyes of patients with final best-corrected visual acuity ≥20/40, axial length (AL) 22-26 mm, and implanted SN60WF IOL were included. Patients with ocular comorbidities and/or intra- or post-operative complications were excluded. Prediction errors of refractive outcome and percentage of eyes within ±0.50D and ±1.00D were compared between the groups for the Holladay 1 and Barrett Universal II (Barrett) formulas. Logistic regression analysis for achievement of ±1.00D was conducted.ResultsFinal analysis included 90 eyes (n = 44, very elderly, n = 46, control patients). Median absolute refractive error (MedAE) with Holladay 1, but not Barrett formula, was significantly higher in the older group (p = 0.02 and p = 0.07, respectively). The MedAE in the older group was lower using the Barrett compared to Holladay 1 (p = 0.02). Fewer older patients than younger patients achieved refraction within ±0.50D and ±1.00D from goal, using the Holladay 1 (p = 0.049 and p = 0.002 respectively). Logistic regression analysis supported the relationship between Holladay 1 predictive refractive error of >1.00D and patient's age (p = 0.046).ConclusionsVery elderly patients undergoing cataract surgery may be prone to reduced refractive precision, particularly with utilization of the Holladay 1 formula.

Published
2020

28. Association of Systemic Medication Use with Glaucoma and Intraocular Pressure: The European Eye Epidemiology Consortium

Author

Vergroesen, Joëlle E., Schuster, Alexander K., Stuart, Kelsey V., Asefa, Nigus G., Cougnard-Grégoire, Audrey, Delcourt, Cécile, Schweitzer, Cédric, Barreto, Patrícia, Coimbra, Rita, Foster, Paul J., Luben, Robert N., Pfeiffer, Norbert, Stingl, Julia V., Kirsten, Toralf, Rauscher, Franziska G., Wirkner, Kerstin, Jansonius, Nomdo M., Arnould, Louis, Creuzot-Garcher, Catherine P., Stricker, Bruno H., Keskini, Christina, Topouzis, Fotis, Bertelsen, Geir, Eggen, Anne E., Bikbov, Mukharram M., Jonas, Jost B., Klaver, Caroline C.W., Ramdas, Wishal D., and Khawaja, Anthony P.

Published
2023
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34. Assessment of psychological resilience in a large cohort of the general population: Validation and norm values of the RS-5.

Author

Reinwarth, Anna C., Hahad, Omar, Ghaemi Kerahrodi, Jasmin, Brähler, Elmar, Lieb, Klaus, Gilan, Donya, Zahn, Daniela, Chalabi, Julian, Schuster, Alexander K., Schepers, Markus, Lackner, Karl J., Schattenberg, Jörn M., Ruf, Wolfram, Wild, Philipp S., Daiber, Andreas, Michal, Matthias, Beutel, Manfred E., and Münzel, Thomas

Subjects
PSYCHOLOGICAL resilience, PSYCHOMETRICS, PSYCHOLOGICAL tests, INCOME, MENTAL illness
Abstract

Background: Psychological resilience is known as a protective factor against mental health disorders for which valid measures are indispensable. The present work aims to evaluate the Resilience Scale-5 (RS-5) psychometrically, and provide norm values. Methods: Data from the Gutenberg Health Study (GHS), encompassing 7,496 participants aged 25 to 86, spanning the years 2017 to 2022, was used. Selectivity, item difficulty, internal consistency, construct and factor validity, as well as factorial invariance were tested. Additionally, correlations and associations with depression, anxiety, and sociodemographic factors were determined. Furthermore, norm values were provided. Results: The RS-5 displayed robust psychometric properties. Participants reported an average resilience score of 28.94 (SD = 5.53, median = 30, IQR = 6, range = 5–35), with those aged ≥75 exhibiting the highest resilience levels (M = 30.21, SD = 5.75, median = 32, IQR = 7). The RS-5 displayed a very good model fit, affirming measurement invariance across sex and age decades. Construct validity found support through anticipated intercorrelations with related psychological constructs. Significant correlations (p <.001) linked higher resilience with female gender, advanced age, higher education, elevated household income, and diminished psychological distress. Conclusion: The RS-5 emerged as a reliable and economic instrument for assessing psychological resilience in individuals aged 25 to 86. The study unraveled distinct sociodemographic characteristics significantly tied to resilience levels within this cohort. In contributing recent norm values tailored to the German population, this research enhances the practical applicability of the RS-5 across diverse contexts and enriches our comprehension of the demographic nuances associated with psychological resilience. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Peripheral hypertrophic subepithelial corneal opacification – Role of tear secretion, medication and systemic diseases.

Author

Riedl, Jana C., Misirkhanova, Aminat, Wasielica‐Poslednik, Joanna, Schuster, Alexander K., Schmidtmann, Irene, Beutel, Manfred E., Pfeiffer, Norbert, and Gericke, Adrian

Subjects
DRY eye syndromes, EYE drops, ACADEMIC medical centers, SIMULATED patients, MEDICAL records
Abstract

Background: Peripheral hypertrophic subepithelial corneal opacification (PHSCO) is a corneal disease that may severely affect vision. The major goal of this study was to test the hypothesis that tear secretion, medication and systemic diseases are associated with PHSCO. Methods: This is a retrospective, case–control study conducted at the Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz. We analysed medical records of patients diagnosed with PHSCO. Sex, age, Schirmer's test II, general medication and medical history were assessed and compared to an age‐ and sex‐matched control group from the Gutenberg Health Study (GHS). Results: One hundred ninety‐five eyes of 112 patients with PHSCO were included. Eighty‐eight patients were female with a mean age of 55.3 ± 14.7 years (23–89 years) and 24 patients were male with a mean age of 59.3 ± 12.6 years (38–84 years). In 83 patients (74.1%) both eyes were involved. The Schirmer's test II was significantly reduced in patients with PHSCO compared to the GHS control group (p < 0.001). Patients with PHSCO were more frequently administered artificial tears and steroid eye drops (p < 0.001) and were more hyperopic than healthy controls (p = 0.01). Systemic diseases or medication did not differ markedly between PHSCO and healthy controls. Conclusion: Reduced tear secretion and more frequent use of artificial tears in patients with PHSCO suggest a link between PHSCO and dry eye disease. The results of the study do not support our hypothesis that PHSCO is associated with systemic diseases. Interestingly, patients with PHSCO were less frequently on β‐blockers than control subjects. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Obesity‐related inflammatory protein signature in cardiovascular clinical outcomes: results from the Gutenberg Health Study

Author

Panova‐Noeva, Marina, primary, Koeck, Thomas, additional, Schoelch, Corinna, additional, Schulz, Andreas, additional, Prochaska, Jürgen H., additional, Michal, Matthias, additional, Strauch, Konstantin, additional, Schuster, Alexander K., additional, Lackner, Karl J., additional, Münzel, Thomas, additional, Hennige, Anita M., additional, and Wild, Philipp S., additional

Published
2024
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43. Tinnitus prevalence as a function of resilience in a German population cohort

Author

Hackenberg, Berit, additional, Döge, Julia, additional, O'Brien, Karoline, additional, Matthias, Christoph, additional, Bahr-Hamm, Katharina, additional, Beutel, Manfred E., additional, Lackner, Karl J, additional, Münzel, Thomas, additional, Schuster, Alexander K, additional, Wild, Philipp, additional, and Chalabi, Julian, additional

Published
2024
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44. Noise annoyance due to different sources is associated with tinnitus presence and distress in the general population

Author

Hahad, Omar, primary, Döge, Julia, additional, Bahr-Hamm, Katharina, additional, Beutel, Manfred E., additional, Kontohow-Beckers, Konstantin, additional, Schuster, Alexander K., additional, Keller, Karsten, additional, Hobohm, Lukas, additional, Schmitt, Volker H., additional, Gianicolo, Emilio, additional, Lackner, Karl J., additional, Daiber, Andreas, additional, Wild, Philipp S., additional, Hackenberg, Berit, additional, and Münzel, Thomas, additional

Published
2024
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46. Prevalence of strabismus and risk factors in adults born preterm with and without retinopathy of prematurity: results from the Gutenberg Prematurity Eye study

Author

Fieß, Achim, primary, Dautzenberg, Kim, additional, Gißler, Sandra, additional, Mildenberger, Eva, additional, Urschitz, Michael S, additional, Elflein, Heike M, additional, Laspas, Panagiotis, additional, Stoffelns, Bernhard M, additional, Pfeiffer, Norbert, additional, and Schuster, Alexander K, additional

Published
2024
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