Search

Your search keyword '"Schulze zur Wiesch J"' showing total 365 results
Start Over Author "Schulze zur Wiesch J"
365 results on '"Schulze zur Wiesch J"'

2. Rare HCV subtypes and retreatment outcomes in a cohort of European DAA-experienced patients

Author

Antoni, C., Teufel, A., Vogelmann, R., Ebert, M., Balavoine, J., Giostra, E., Berning, M., Hampe, J., Boettler, T., Neumann-Haefelin, C., Thimme, R., De Gottardi, A., Rauch, A., Semmo, N., Ellenrieder, V., Gress, M., Herrmann, A., Stallmach, A., Hoffmann, D., Protzer, U., Kodal, A., Löbermann, M., Götze, T., Keitel-Anselmino, V., Lange, C.M., Zachoval, R., Mayerle, J., Maieron, A., Michl, P., Merle, U., Moradpour, D., Chave, J.-P., Muche, M., Epple, H.-J., Müller-Schilling, M., Kocheise, F., Müller, T., Tacke, F., Roeb, E., Rissland, J., Krawczyk, M., Schulze, P., Semela, D., Spengler, U., Rockstroh, J., Strassburg, C.P., Siebler, J., Schulze zur Wiesch, J., Piecha, F., von Felden, J., Jordan, S., Lohse, A., Sprinzl, M., Galle, P., Stauber, R., Strey, B., Steckstor, W., Schmiegel, W., Brockmeyer, N.H., Canbay, A., Trautwein, C., Uschner, F., Trebicka, J., Weber, T., Wedemeyer, H., Cornberg, M., Manns, M., Wietzke-Braun, P., Günther, R., Willuweit, K., Hilgard, G., Schmidt, H., Zizer, E., Backhus, J., Seufferlein, T., Al-Taie, O., Angeli, W., Beckebaum, S., Erhardt, A., Garrido-Lüneburg, A., Gattringer, H., Genné, D., Gschwantler, M., Gundling, F., Hametner, S., Schöfl, R., Haag, S., Heinzow, H., Heyer, T., Hirschi, C., Jussios, A., Kanzler, S., Kordecki, N., Kraus, M., Kullig, U., Wollschläger, S., Magenta, L., Beretta-Piccoli, B. Terziroli, Menges, M., Mohr, L., Muehlenberg, K., Niederau, C., Paulweber, B., Petrides, A., Pinkernell, M., Piso, R., Rambach, W., Reinhardt, L., Reiser, M., Riecken, B., Rieke, A., Roth, J., Schelling, M., Schlee, P., Schneider, A., Scholz, D., Schott, E., Schuchmann, M., Schulten-Baumer, U., Seelhoff, A., Stich, A., Stickel, F., Ungemach, J., Walter, E., Weber, A., Wege, H., Winzer, T., Abels, W., Adler, M., Audebert, F., Baermann, C., Bästlein, E., Barth, R., Barthel, K., Becker, W., Behrends, J., Benninger, J., Berger, F., Berzow, D., Beyer, T., Bierbaum, M., Blaukat, O., Bodtländer, A., Böhm, G., Börner, N., Bohr, U., Bokemeyer, B., Bruch, H.R., Bucholz, D., Buggisch, P., Matschenz, K., Petersen, J., Burkhard, O., Busch, N., Chirca, C., Delker, R., Diedrich, J., Frank, M., Diehl, M., Tal, A.O., Schneider, M., Dienethal, A., Dietel, P., Dikopoulos, N., Dreck, M., Dreher, F., Drude, L., Ende, K., Ehrle, U., Baumgartl, K., Emke, F., Glosemeyer, R., Felten, G., Hüppe, D., Fischer, J., Fischer, U., Frederking, D., Frick, B., Friese, G., Gantke, B., Geyer, P., Schwind, H.R., Glas, M., Glaunsinger, T., Goebel, F., Göbel, U., Görlitz, B., Graf, R., Gruber, H., Hartmann, C., Klag, C., Härter, G., Herder, M., Heuchel, T., Heuer, S., Hinrichsen, H., Seegers, B., Höffl, K.-H., Hörster, H., Sonne, J.-U., Hofmann, W.P., Holst, F., Hunstiger, M., Hurst, A., Jägel-Guedes, E., John, C., Jung, M., Kallinowski, B., Kapzan, B., Kerzel, W., Khaykin, P., Klarhof, M., Klüppelberg, U., Wolfratshausen, Klugewitz, K., Knapp, B., Knevels, U., Kochsiek, T., Körfer, A., Köster, A., Kuhn, M., Langekamp, A., Künzig, B., Link, R., Littman, M., Löhr, H., Lutz, T., Gute, P., Knecht, G., Lutz, U., Mainz, D., Mahle, I., Maurer, P., Mauss, S., Mayer, C., Möller, H., Heyne, R., Moritzen, D., Mroß, M., Mundlos, M., Naumann, U., Nehls, O., K, Ningel, R., Oelmann, A., Olejnik, H., Gadow, K., Pascher, E., Philipp, A., Pichler, M., Polzien, F., Raddant, R., Riedel, M., Rietzler, S., Rössle, M., Rufle, W., Rump, A., Schewe, C., Hoffmann, C., Schleehauf, D., Schmidt, W., Schmidt-Heinevetter, G., Fabris, J. Schmidtler-von, Schneider, L., Schober, A., Niehaus-Hahn, S., Schwenzer, J., Seidel, T., Seitel, G., Sick, C., Simon, K., Stähler, D., Stenschke, F., Steffens, H., Stein, K., Steinmüller, M., Sternfeld, T., Svensson, K., Tacke, W., Teuber, G., Teubner, K., Thieringer, J., Tomesch, A., Trappe, U., Ullrich, J., Urban, G., Usadel, S., von Lucadou, A., Weinberger, F., Werheid-Dobers, M., Werner, P., Winter, T., Zehnter, E., Zipf, A., Dietz, Julia, Graf, Christiana, Berg, Christoph P., Port, Kerstin, Deterding, Katja, Buggisch, Peter, Peiffer, Kai-Henrik, Vermehren, Johannes, Dultz, Georg, Geier, Andreas, Reiter, Florian P., Bruns, Tony, Schattenberg, Jörn M., Durmashkina, Elena, Gustot, Thierry, Moreno, Christophe, Trauth, Janina, Discher, Thomas, Fischer, Janett, Berg, Thomas, Kremer, Andreas E., Müllhaupt, Beat, Zeuzem, Stefan, and Sarrazin, Christoph

Published
2024
Full Text
View/download PDF

5. Patterns of Resistance-Associated Substitutions in Patients With Chronic HCV Infection Following Treatment With Direct-Acting Antivirals

Author

Antoni, C., Vogelmann, R., Ebert, M., Backhus, J., Seufferlein, T., Balavoine, J., Giostra, E., Berg, C., Cornberg, M., Wedemeyer, H., Manns, M., De Gottardi, A., Esteban, R., Discher, T., Roeb, E., Gress, M., Günther, R., Wietzke-Braun, P., Herrmann, A., Stallmach, A., Hoffmann, D., Klinker, H., Kodal, A., Lammert, F., Löbermann, M., Schulze zur Wiesch, J., von Felden, J., Piecha, F., Lohse, A., Götze, T., Malfertheiner, P., Mayerle, J., Moradpour, D., Moreno, C., Neumann-Haefelin, C., Thimme, R., Reinhardt, L., Ellenrieder, V., Schattenberg, J., Sprinzl, M., Galle, P., Schmidt, J., Schott, E., Epple, H.-J., Siebler, J., Stauber, R., Steckstor, M., Schmiegel, W., Stremmel, W., Strey, B., Tomasiewicz, K., Trautwein, C., Zachoval, R., Angeli, W., Beckebaum, S., Doberauer, C., Ende, K., Erhardt, A., Garrido-Lüneburg, A., Gattringer, H., Genné, D., Gschwantler, M., Gundling, F., Hartmann, C., Heyer, T., Hirschi, C., Kanzler, S., Kordecki, N., Kraus, M., Kullig, U., Magenta, L., Terziroli Beretta-Piccoli, B., Menges, M., Mohr, L., Muehlenberg, K., Niederau, C., Paulweber, B., Petrides, A., Piso, R., Rambach, W., Reiser, M., Riecken, B., Roth, J., Schöfl, R., Maieron, A., Schneider, A., Schuchmann, M., Schulten-Baumer, U., Seelhoff, A., Semela, D., Stich, A., Vollmer, C., Brückner, J., Ungemach, J., Walter, E., Weber, A., Winzer, T., Abels, W., Adler, M., Audebert, F., Baermann, C., Bästlein, E., Barth, R., Barthel, K., Baumgartl, K., Becker, W., Benninger, J., Beyer, T., Bodtländer, A., Böhm, G., Bohr, U., Moll, A., Naumann, U., Börner, N., Bruch, H.R., Busch, N., Burkhard, O., Chirca, C., Dienethal, A., Dietel, P., Dreher, F., Efken, P., Ehrle, U., Emke, F., Fischer, J., Fischer, U., Frederking, D., Frick, B., Gantke B, B., Geyer, P., Glaunsinger, T., Goebel, F., Göbel, U., Graf, R., Herder, M., Heuchel, T., Heuer, S., Heyne, R., Höffl, K.H., Hofmann, W.P., Holst, F., Hörster, H., John, C., Jung, M.C., Kallinowski, B., Kerzel, W., Khaykin, P., Klarhof, M., Knapp, B., Knevels, U., Körfer, A., Köster, A., Künzig, B., Langenkamp, A., Kuhn, M., Littman, M., Löhr, H., Ludwig, L., Lutz, U., Maurer, P., Mayer, C., Meister, V., Moritzen, D., Mroß, M., Mundlos, M., Nehls, O., Ningel, K., Oelmann, A., Olejnik, H., Pascher, E., Philipp, A., Pichler, M., Polzien, F., Raddant, R., Riedel, M., Rietzler, S., Rump, A., Schmidt, W., Schmidtler-von Fabris, J., Schneider, L., Schober, A., Schwenzer, J., Seidel, T., Seitel, G., Sick, C., Simon, K., Stähler, D., Steffens, H., Svensson, K., Tacke, W., Teubner, K., Thieringer, J., Trappe, U., Ullrich, J., Usadel, S., von Lucadou, A., Werheid-Dobers, M., Zehnter, E., Zipf, A., Dietz, Julia, Susser, Simone, Vermehren, Johannes, Peiffer, Kai-Henrik, Grammatikos, Georgios, Berger, Annemarie, Ferenci, Peter, Buti, Maria, Müllhaupt, Beat, Hunyady, Bela, Hinrichsen, Holger, Mauss, Stefan, Petersen, Jörg, Buggisch, Peter, Felten, Gisela, Hüppe, Dietrich, Knecht, Gaby, Lutz, Thomas, Schott, Eckart, Berg, Christoph, Spengler, Ulrich, von Hahn, Thomas, Berg, Thomas, Zeuzem, Stefan, and Sarrazin, Christoph

Published
2018
Full Text
View/download PDF

6. High vaccination coverage and infection rate result in a robust SARS‐CoV‐2‐specific immunity in the majority of liver cirrhosis and transplant patients: A single‐center cross‐sectional study

Author

Schulenburg, P., Herting, A., Harberts, A., Lütgehetmann, M., Jahnke‐Triankowski, J., Pischke, S., Piecha, F., Drolz, A., Jörg, V., Hübener, P., Wehmeyer, M., Addo, M. M., Fischer, L., Lohse, A. W., Schulze Zur Wiesch, J., and Sterneck, M.

Abstract

In the third year of the SARS‐CoV‐2 pandemic, little is known about the vaccine‐ and infection‐induced immune response in liver transplant recipients (LTR) and liver cirrhosis patients (LCP). This cross‐sectional study assessed the vaccination coverage, infection rate, and the resulting humoral and cellular SARS‐CoV‐2‐specific immune responses in a cohort of LTR and LCP at the University Medical Center Hamburg‐Eppendorf, Germany between March and May 2023. Clinical and laboratory data from 244 consecutive patients (160 LTR and 84 LCP) were collected via chart review and a patient survey. Immune responses were determined via standard spike(S)‐ and nucleocapsid‐protein serology and a spike‐specific Interferon‐gamma release assay (IGRA). On average, LTR and LCP were vaccinated 3.7 and 3.3 times, respectively and 59.4% of patients received ≥4 vaccinations. Altogether, 68.1% (109/160) of LTR and 70.2% (59/84) of LCP experienced a SARS‐CoV‐2 infection. Most infections occurred during the Omicron wave in 2022 after an average of 3.0 vaccinations. Overall, the hospitalization rate was low (<6%) in both groups. An average of 4.3 antigen contacts by vaccination and/or infection resulted in a seroconversion rate of 98.4%. However, 17.5% (28/160) of LTR and 8.3% (7/84) of LCP demonstrated only low anti‐S titers (<1000 AU/ml), and 24.6% (16/65) of LTR and 20.4% (10/59) of LCP had negative or low IGRA responses. Patients with hybrid immunity (vaccination plus infection) elicited significantly higher anti‐S titers compared with uninfected patients with the same number of spike antigen contacts. A total of 22.2% of patients refused additional booster vaccinations. By spring 2023, high vaccination coverage and infection rate have resulted in a robust, mostly hybrid, humoral and cellular immune response in most LTR and LCP. However, booster vaccinations with vaccines covering new variants seem advisable, especially in patients with low immune responses and risk factors for severe disease.

Published
2024
Full Text
View/download PDF

7. Virushepatitis

Author

Boesecke, C., primary, Nierhoff, D., additional, and Schulze zur Wiesch, J., additional

Published
2018
Full Text
View/download PDF

13. Response to discontinuation of nucleos(t)ide analogue treatment in HBeAg-negative chronic hepatitis B: results from the Stop-NUC trial

Author

van Bömmel, F, additional, Stein, K, additional, Heyne, R, additional, Möller, H, additional, Petersen, J, additional, Buggisch, P, additional, Berg, C, additional, Werner, C, additional, Zeuzem, S, additional, Stallmach, A, additional, Herrmann, A, additional, Sprinzl, M, additional, Grambihler, A, additional, Schott, E, additional, Benckert, J, additional, Pathil-Warth, A, additional, von Arnim, U, additional, Keitel, V, additional, Trauth, J, additional, Simon, KG, additional, Trautwein, C, additional, Trein, A, additional, Hüppe, D, additional, Cornberg, M, additional, Lammert, F, additional, Ingilitz, P, additional, Zachoval, R, additional, Hinrichsen, H, additional, Zipprich, A, additional, Klinker, H, additional, Schulze zur Wiesch, J, additional, Brosteanu, O, additional, Schmiedeknecht, A, additional, and Berg, T, additional

Published
2020
Full Text
View/download PDF

14. Diagnostic accuracy of noninvasive markers of steatosis, NASH, and liver fibrosis in HIV-monoinfected individuals at risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results from the ECHAM study

Author

Lemoine, M, Assoumou, L, De Wit, S, Girard, P-M, Valantin, MA, Katlama, C, Necsoi, C, Campa, P, Huefner, AD, Schulze Zur Wiesch, J, Rougier, H, Bastard, J-P, Stocker, H, Mauss, S, Serfaty, L, Ratziu, V, Menu, Y, Schlue, J, Behrens, G, Bedossa, P, Capeau, J, Ingiliz, P, Costagliola, D, and ANRS-ECHAM Group

Subjects
Liver Cirrhosis, Male, medicine.medical_specialty, Liver fibrosis, ANRS-ECHAM Group, Population, Diagnostic accuracy, HIV Infections, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Adipokines, Belgium, Fibrosis, Non-alcoholic Fatty Liver Disease, Internal medicine, Germany, Virology, Nonalcoholic fatty liver disease, Medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Prospective Studies, Prospective cohort study, education, Aged, Ultrasonography, 2. Zero hunger, education.field_of_study, medicine.diagnostic_test, business.industry, 1103 Clinical Sciences, Middle Aged, medicine.disease, Magnetic Resonance Imaging, 3. Good health, Infectious Diseases, Anti-Retroviral Agents, Liver biopsy, Elasticity Imaging Techniques, 030211 gastroenterology & hepatology, Female, France, Steatosis, business
Abstract

BACKGROUND: HIV-monoinfected individuals are at high risk of nonalcoholic fatty liver disease. Noninvasive tests of steatosis, nonalcoholic steatohepatitis (NASH), and fibrosis have been poorly assessed in this population. Using liver biopsy (LB) as a reference, we assessed the accuracy of noninvasive methods for their respective diagnosis: magnetic resonance imaging proton-density-fat-fraction (MRI-PDFF), FibroScan/controlled attenuation parameter (CAP), and biochemical tests. METHODS: We enrolled antiretroviral therapy-controlled participants with persistently elevated transaminases and/or metabolic syndrome, and/or lipodystrophy. All had hepatic MRI-PDFF, FibroScan/CAP, FibroTest/NashTest/SteatoTest, APRI, FIB-4, and nonalcoholic fatty liver disease-fibrosis score. A LB was indicated if suspected significant fibrosis (FibroScan ≥7.1 kPa and/or FibroTest ≥0.49). Performance was considered as good if area under a receiver operating characteristic curves (AUROCs) was >0.80. RESULTS: Among the 140 patients with suspected significant fibrosis out of the 402 eligible patients, 49 had had a LB: median age of 54 years (53-65), body mass index: 26 kg/m (24-30), steatosis in 37 (76%), NASH in 23 (47%), and fibrosis in 31 (63%) patients [F2: 7 (14%); F3: 6 (12%); and F4: 2 (4%)]. Regarding steatosis, MRI-PDFF had excellent and CAP good performances with AUROCs at 0.98 (95% confidence interval: 0.96 to 1.00) and 0.88 (0.76 to 0.99), respectively, whereas the AUROCs of SteatoTest was 0.68 (0.51 to 0.85). Regarding fibrosis (≥F2), APRI and FIB-4 had good performance with AUROCs at 0.86 (0.74 to 0.98) and 0.81 (0.67 to 0.95). By contrast, FibroScan and FibroTest had poor AUROCs [0.61 (0.43 to 0.79) and 0.61 (0.44 to 0.78)], with very low specificity. Regarding NASH, alanine aminotransferase ≥36 IU/L had good performance with AUROCs of 0.83 (0.71 to 0.94), whereas the NashTest had an AUROC of 0.60 (0.44 to 0.76). CONCLUSIONS: In HIV-monoinfected patients, MRI-PDFF and FibroScan/CAP are highly accurate for the diagnosis of steatosis. The alanine aminotransferase level and APRI should be considered for the detection of NASH and fibrosis.

Published
2019

17. Persistenz von HCV Resistenz-assoziierten Substitutionen in NS3, NS5A und NS5B nach einem DAA Therapieversagen

Author

Dietz, J, additional, Vermehren, J, additional, Peiffer, KH, additional, Müllhaupt, B, additional, Buggisch, P, additional, Matschenz, K, additional, Schattenberg, J, additional, Antoni, C, additional, Mauss, S, additional, Durmashkina, E, additional, Niederau, C, additional, Discher, T, additional, Trauth, J, additional, Schulze zur Wiesch, J, additional, Piecha, F, additional, Müller, T, additional, Berg, T, additional, Neumann-Haefelin, C, additional, Berg, C, additional, Zeuzem, S, additional, and Sarrazin, C, additional

Published
2019
Full Text
View/download PDF

18. Allogeneic stem cell transplant in individuals living with HIV-1: an update of the IciStem Consortium

Author

Wensing, AMJ, primary, Salgado, M., additional, Kwon, M., additional, Eberhard, J.M., additional, Saez-Cirion, A., additional, Schulze zur Wiesch, J., additional, Hütter, G., additional, Badiola-González, J., additional, Bandera, A., additional, Barrett, L., additional, Gupta, R.K., additional, Jensen, B.E., additional, Kuball, J.H.E., additional, Martín Carbonero, L., additional, Nabergoj, M., additional, Raj, K., additional, Saldaña-Moreno, R., additional, Scarlatti, G., additional, Vandekerckhove, L., additional, Díez Martín, J.L., additional, Nijhuis, M., additional, and Martínez-Picado, J., additional

Published
2019
Full Text
View/download PDF

22. Viral escape contributes to the failure of hepatitis D virus (HDV)-specific CD8+ T cells and drives population-level evolution of HDV

Author

Oberhardt, V, additional, Karimzadeh, H, additional, Kiraithe, M, additional, Salimi Alizei, E, additional, Bockmann, JH, additional, Schulze zur Wiesch, J, additional, Budeus, B, additional, Hoffmann, D, additional, Wedemeyer, H, additional, Rodríguez-Frías, F, additional, Casillas, R, additional, Buti, M, additional, Smedile, A, additional, Alavian, SM, additional, Heinold, A, additional, Emmerich, F, additional, Panning, M, additional, Gostick, E, additional, Price, DA, additional, Timm, J, additional, Hofmann, M, additional, Raziorrouh, B, additional, Thimme, R, additional, Protzer, U, additional, Roggendorf, M, additional, and Neumann-Haefelin, C, additional

Published
2019
Full Text
View/download PDF

23. Increased frequency of TIGIT+CD73-CD8+ T cells with a TOX+ TCF-1low profile in patients with newly diagnosed and relapsed AML.

Author

Brauneck, F., Haag, F., Woost, R., Wildner, N., Tolosa, E., Rissiek, A., Vohwinkel, G., Wellbrock, J., Bokemeyer, C., Schulze zur Wiesch, J., Ackermann, C., and Fiedler, W.

Subjects
T cells, ACUTE myeloid leukemia, TRANSCRIPTION factors, BONE marrow
Abstract

The inhibitory receptor TIGIT, as well as theectonucleotidases CD39 and CD73 constitute potential exhaustion markers for T cells. Detailed analysis of these markers can shed light into dysregulation of the T-cell response in acute myeloid leukemia (AML) and will help to identify potential therapeutic targets. The phenotype and expression of transcription factors was assessed on different T-cell populations derived from peripheral blood (PB, n = 38) and bone marrow (BM, n = 43). PB and BM from patients with AML diagnosis, in remission and at relapse were compared with PB from healthy volunteers (HD) (n = 12) using multiparameter flow cytometry. An increased frequency of terminally differentiated (CD45R-CCR7-)CD8+ T cells was detected in PB and BM regardless of the disease state. Moreover, we detected an increased frequency of two distinct T-cell populations characterized by the co-expression of PD-1 or CD39 on TIGIT+CD73-CD8- T cells in newly diagnosed and relapsed AML in comparison to HDs. In contrast to the PD-1+TIGIT+CD73-CD8+ T-cell population, the frequency of CD39+TIGIT+CD73-CD8+ T cells was normalized in remission. PD-1+- and CD39+TIGIT+CD73-CD8+ T cells exhibited additional features of exhaustion by decreased expression of CD127 and TCF-1 and increased intracellular expression of the transcription factor TOX. CD8+ T cells in AML exhibit a key signature of two subpopulations, PD-1+TOX+TIGIT+CD73-CD8+- and CD39+TOX+TIGIT+CD73-CD8+ T cells that were increased at different stages of the disease. These results provide a rationale to analyze TIGIT blockade in combination with inhibition of the purinergic signaling and depletion of TOX to improve T-cell mediated cytotoxicity in AML. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

24. Prävalenz von HCV NS5A Resistenzen und Therapieansprechen bei DAA-naiven Patienten mit einer chronischen Genotyp (GT) 1a Hepatitis C Virusinfektion

Author

Dietz, J, additional, Vermehren, J, additional, Peiffer, KH, additional, Welzel, T, additional, Petersen, J, additional, Matzschenz, K, additional, Klinker, H, additional, Schulze zur Wiesch, J, additional, Hinrichsen, H, additional, Discher, T, additional, Reinhardt, L, additional, Mauss, S, additional, Müller-Schilling, M, additional, Müller, T, additional, Niederau, C, additional, Neumann-Haefelin, C, additional, Berg, C, additional, Zeuzem, S, additional, and Sarrazin, C, additional

Published
2018
Full Text
View/download PDF

28. Significant changes of HCV patient characteristics over time in the era of direct antiviral agent therapy – are all HCV subpopulations treated similarly? – Results from the German hepatitis C Cohort

Author

Christensen, S., primary, Ingiliz, P., additional, Schulze Zur Wiesch, J., additional, Schewe, K., additional, Boesecke, C., additional, Hüppe, D., additional, Baumgarten, A., additional, Thomas, L., additional, Schmutz, G., additional, Georg, S.K., additional, Florian, B., additional, Heiner, B., additional, and Mauss, S., additional

Published
2018
Full Text
View/download PDF

29. High efficacy of sofosbuvir/velpatasvir and impact of baseline resistance-associated substitutions in hepatitis C genotype 3 infection

Author

von Felden, J., primary, Vermehren, J., additional, Ingiliz, P., additional, Mauss, S., additional, Lutz, T., additional, Simon, K. G., additional, Busch, H. W., additional, Baumgarten, A., additional, Schewe, K., additional, Hueppe, D., additional, Boesecke, C., additional, Rockstroh, J. K., additional, Daeumer, M., additional, Luebke, N., additional, Timm, J., additional, Schulze zur Wiesch, J., additional, Sarrazin, C., additional, and Christensen, S., additional

Published
2018
Full Text
View/download PDF

30. Patterns of Resistance-Associated Substitutions in Patients With Chronic HCV Infection Following Treatment With Direct-Acting Antivirals

Author

Dietz, Julia, primary, Susser, Simone, additional, Vermehren, Johannes, additional, Peiffer, Kai-Henrik, additional, Grammatikos, Georgios, additional, Berger, Annemarie, additional, Ferenci, Peter, additional, Buti, Maria, additional, Müllhaupt, Beat, additional, Hunyady, Bela, additional, Hinrichsen, Holger, additional, Mauss, Stefan, additional, Petersen, Jörg, additional, Buggisch, Peter, additional, Felten, Gisela, additional, Hüppe, Dietrich, additional, Knecht, Gaby, additional, Lutz, Thomas, additional, Schott, Eckart, additional, Berg, Christoph, additional, Spengler, Ulrich, additional, von Hahn, Thomas, additional, Berg, Thomas, additional, Zeuzem, Stefan, additional, Sarrazin, Christoph, additional, Antoni, C., additional, Vogelmann, R., additional, Ebert, M., additional, Backhus, J., additional, Seufferlein, T., additional, Balavoine, J., additional, Giostra, E., additional, Berg, C., additional, Cornberg, M., additional, Wedemeyer, H., additional, Manns, M., additional, De Gottardi, A., additional, Esteban, R., additional, Discher, T., additional, Roeb, E., additional, Gress, M., additional, Günther, R., additional, Wietzke-Braun, P., additional, Herrmann, A., additional, Stallmach, A., additional, Hoffmann, D., additional, Klinker, H., additional, Kodal, A., additional, Lammert, F., additional, Löbermann, M., additional, Schulze zur Wiesch, J., additional, von Felden, J., additional, Piecha, F., additional, Lohse, A., additional, Götze, T., additional, Malfertheiner, P., additional, Mayerle, J., additional, Moradpour, D., additional, Moreno, C., additional, Neumann-Haefelin, C., additional, Thimme, R., additional, Reinhardt, L., additional, Ellenrieder, V., additional, Schattenberg, J., additional, Sprinzl, M., additional, Galle, P., additional, Schmidt, J., additional, Schott, E., additional, Epple, H.-J., additional, Siebler, J., additional, Stauber, R., additional, Steckstor, M., additional, Schmiegel, W., additional, Stremmel, W., additional, Strey, B., additional, Tomasiewicz, K., additional, Trautwein, C., additional, Zachoval, R., additional, Angeli, W., additional, Beckebaum, S., additional, Doberauer, C., additional, Ende, K., additional, Erhardt, A., additional, Garrido-Lüneburg, A., additional, Gattringer, H., additional, Genné, D., additional, Gschwantler, M., additional, Gundling, F., additional, Hartmann, C., additional, Heyer, T., additional, Hirschi, C., additional, Kanzler, S., additional, Kordecki, N., additional, Kraus, M., additional, Kullig, U., additional, Magenta, L., additional, Terziroli Beretta-Piccoli, B., additional, Menges, M., additional, Mohr, L., additional, Muehlenberg, K., additional, Niederau, C., additional, Paulweber, B., additional, Petrides, A., additional, Piso, R., additional, Rambach, W., additional, Reiser, M., additional, Riecken, B., additional, Roth, J., additional, Schöfl, R., additional, Maieron, A., additional, Schneider, A., additional, Schuchmann, M., additional, Schulten-Baumer, U., additional, Seelhoff, A., additional, Semela, D., additional, Stich, A., additional, Vollmer, C., additional, Brückner, J., additional, Ungemach, J., additional, Walter, E., additional, Weber, A., additional, Winzer, T., additional, Abels, W., additional, Adler, M., additional, Audebert, F., additional, Baermann, C., additional, Bästlein, E., additional, Barth, R., additional, Barthel, K., additional, Baumgartl, K., additional, Becker, W., additional, Benninger, J., additional, Beyer, T., additional, Bodtländer, A., additional, Böhm, G., additional, Bohr, U., additional, Moll, A., additional, Naumann, U., additional, Börner, N., additional, Bruch, H.R., additional, Busch, N., additional, Burkhard, O., additional, Chirca, C., additional, Dienethal, A., additional, Dietel, P., additional, Dreher, F., additional, Efken, P., additional, Ehrle, U., additional, Emke, F., additional, Fischer, J., additional, Fischer, U., additional, Frederking, D., additional, Frick, B., additional, Gantke B, B., additional, Geyer, P., additional, Glaunsinger, T., additional, Goebel, F., additional, Göbel, U., additional, Graf, R., additional, Herder, M., additional, Heuchel, T., additional, Heuer, S., additional, Heyne, R., additional, Höffl, K.H., additional, Hofmann, W.P., additional, Holst, F., additional, Hörster, H., additional, John, C., additional, Jung, M.C., additional, Kallinowski, B., additional, Kerzel, W., additional, Khaykin, P., additional, Klarhof, M., additional, Knapp, B., additional, Knevels, U., additional, Körfer, A., additional, Köster, A., additional, Künzig, B., additional, Langenkamp, A., additional, Kuhn, M., additional, Littman, M., additional, Löhr, H., additional, Ludwig, L., additional, Lutz, U., additional, Maurer, P., additional, Mayer, C., additional, Meister, V., additional, Moritzen, D., additional, Mroß, M., additional, Mundlos, M., additional, Nehls, O., additional, Ningel, K., additional, Oelmann, A., additional, Olejnik, H., additional, Pascher, E., additional, Philipp, A., additional, Pichler, M., additional, Polzien, F., additional, Raddant, R., additional, Riedel, M., additional, Rietzler, S., additional, Rump, A., additional, Schmidt, W., additional, Schmidtler-von Fabris, J., additional, Schneider, L., additional, Schober, A., additional, Schwenzer, J., additional, Seidel, T., additional, Seitel, G., additional, Sick, C., additional, Simon, K., additional, Stähler, D., additional, Steffens, H., additional, Svensson, K., additional, Tacke, W., additional, Teubner, K., additional, Thieringer, J., additional, Trappe, U., additional, Ullrich, J., additional, Usadel, S., additional, von Lucadou, A., additional, Werheid-Dobers, M., additional, Zehnter, E., additional, and Zipf, A., additional

Published
2018
Full Text
View/download PDF

40. HIV-seroreversion dynamics after allogeneic stem cell transplantation

Author

Salgado, M., primary, González, V., additional, Rivaya, B., additional, Gálvez, C.r., additional, Kwon, M., additional, Badiola, J., additional, Bandera, A., additional, Jensen, B., additional, Vandekerckhove, L., additional, Raj, K., additional, Nijhuis, M., additional, Jurado, Manuel, additional, Schulze zur Wiesch, J., additional, Saez-Cirión, A., additional, Luis Diez-Martin, J., additional, Wensing, A., additional, and Martinez-Picado, J., additional

Published
2017
Full Text
View/download PDF

42. Untersuchung von HCV Resistenzen in Verbindung mit dem Therapieansprechen bei Patienten mit einer chronischen Hepatitis C Genotyp 4 Infektion

Author

Dietz, J, additional, Susser, S, additional, Vermehren, J, additional, Peiffer, KH, additional, Welzel, T, additional, Grammatikos, G, additional, Müllhaupt, B, additional, Wursthorn, K, additional, Petersen, J, additional, Schattenberg, J, additional, Chave, JP, additional, Niederau, C, additional, Felden, J, additional, Schulze zur Wiesch, J, additional, Moreno, C, additional, Hahn, T, additional, Berg, T, additional, Berg, C, additional, Zeuzem, S, additional, and Sarrazin, C, additional

Published
2017
Full Text
View/download PDF

44. Liver steatosis and fibrosis in at-risk European HIV-monoinfected patients

Author

Lemoine, M., primary, Assoumou, L., additional, Ingiliz, P., additional, Girard, P.-M., additional, De Wit, S., additional, Valantin, M.-A., additional, Huefner, A., additional, Schulze zur Wiesch, J., additional, Mauss, S., additional, Menu, Y., additional, Bedossa, P., additional, Capeau, J., additional, Costagliola, D., additional, and Behrens, G., additional

Published
2017
Full Text
View/download PDF

45. Resistance patterns in patients with chronic hepatitis C genotype 4 infection and treatment outcome

Author

Dietz, J., primary, Vermehren, J., additional, Susser, S., additional, Peiffer, K.-H., additional, Grammatikos, G., additional, Perner, D., additional, Müllhaupt, B., additional, Buggisch, P., additional, Petersen, J., additional, Schattenberg, J., additional, Galle, P., additional, Chave, J.-P., additional, Kuhn, M., additional, Zachoval, R., additional, Niederau, C., additional, Schulze zur Wiesch, J., additional, Moreno, C., additional, Berg, T., additional, Berg, C., additional, Zeuzem, S., additional, and Sarrazin, C., additional

Published
2017
Full Text
View/download PDF

46. B CELLS WITH VIRUS‐NEUTRALIZING IGHV1‐69 MUTATIONS SHOW LYMPHOMA‐LIKE TRANSCRIPTOMES IN PATIENTS WITH CHRONIC HEPATITIS C INFECTION.

Author

Schultheiß, C., Willscher, E., Paschold, L., Ackermann, C., Escher, M., Scholz, R., Knapp, M., Lützkendorf, J., Müller, L., Schulze zur Wiesch, J., and Binder, M.

Subjects
CHRONIC hepatitis C, B cells, B cell receptors, TRANSCRIPTOMES, AGAMMAGLOBULINEMIA
Abstract

B Methods: b We sequenced B cell repertoires in patients with chronic HCV infection and HCV patients with a sustained virological response (SVR) after DAA therapy. B CELLS WITH VIRUS-NEUTRALIZING IGHV1-69 MUTATIONS SHOW LYMPHOMA-LIKE TRANSCRIPTOMES IN PATIENTS WITH CHRONIC HEPATITIS C INFECTION B Introduction: b Chronic hepatitis C virus (HCV) infection leads to a complex interplay with adaptive immune cells that may result in B cell dyscrasias such as type II mixed cryoglobulinemia and lymphoma. [Extracted from the article]

Published
2023
Full Text
View/download PDF

48. Six weeks of Sofosbuvir/Ledipasvir treatment of acute hepatitis C Virus genotype 1 monoinfection: Final results of the German HepNet Acute HCV IV Study

Author

Deterding, K, additional, Spinner, CD, additional, Schott, E, additional, Welzel, TM, additional, Gerken, G, additional, Klinker, H, additional, Spengler, U, additional, Wiegand, J, additional, Schulze zur Wiesch, J, additional, Pathil, A, additional, Cornberg, M, additional, Umgelter, A, additional, Zöllner, C, additional, Zeuzem, S, additional, Papkalla, A, additional, Weber, K, additional, Hardtke, S, additional, der Leyen, H, additional, Koch, A, additional, Witzendorff, D, additional, Manns, MP, additional, and Wedemeyer, H, additional

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results