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88 results on '"Schuermann D."'

1. Measurement of 1323 and 1487 keV resonances in 15N({\alpha}, {\gamma})19F with the recoil separator ERNA

Author

Di Leva, A., Imbriani, G., Buompane, R., Gialanella, L., Best, A., Cristallo, S., De Cesare, M., D'Onofrio, A., Duarte, J. G., Gasques, L. R., Morales-Gallegos, L., Pezzella, A., Porzio, G., Rapagnani, D., Roca, V., Romoli, M., Schürmann, D., Straniero, O., and Terrasi, F.

Subjects
Nuclear Experiment
Abstract

The origin of fluorine is a widely debated issue. Nevertheless, the ^{15}N({\alpha},{\gamma})^{19}F reaction is a common feature among the various production channels so far proposed. Its reaction rate at relevant temperatures is determined by a number of narrow resonances together with the DC component and the tails of the two broad resonances at E_{c.m.} = 1323 and 1487 keV. Measurement through the direct detection of the 19F recoil ions with the European Recoil separator for Nuclear Astrophysics (ERNA) were performed. The reaction was initiated by a 15N beam impinging onto a 4He windowless gas target. The observed yield of the resonances at Ec.m. = 1323 and 1487 keV is used to determine their widths in the {\alpha} and {\gamma} channels. We show that a direct measurement of the cross section of the ^{15}N({\alpha},{\gamma})^{19}F reaction can be successfully obtained with the Recoil Separator ERNA, and the widths {\Gamma}_{\gamma} and {\Gamma}_{\alpha} of the two broad resonances have been determined. While a fair agreement is found with earlier determination of the widths of the 1487 keV resonance, a significant difference is found for the 1323 keV resonance {\Gamma}_{\alpha} . The revision of the widths of the two more relevant broad resonances in the 15N({\alpha},{\gamma})19F reaction presented in this work is the first step toward a more firm determination of the reaction rate. At present, the residual uncertainty at the temperatures of the ^{19}F stellar nucleosynthesis is dominated by the uncertainties affecting the Direct Capture component and the 364 keV narrow resonance, both so far investigated only through indirect experiments., Comment: 8 pages, 11 figures. Accepted for publication in PRC

Published
2017
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2. Lifetime measurement of the 6792 keV state in 15O, important for the astrophysical S factor extrapolation in 14N(p,g)15O

Author

Schuermann, D., Kunz, R., Lingner, I., Rolfs, C., Schuemann, F., Strieder, F., and Trautvetter, H. -P.

Subjects
Nuclear Experiment
Abstract

We report on a new lifetime measurement of the E_x=6792 keV state in 15O via the Doppler-shift attenuation method at the E=259 keV resonance in the reaction 14N(p,g)15O. This subthreshold state is of particular importance for the determination of the ground state astrophysical S factor of 14N(p,g)15O at stellar energies. The measurement technique has been significantly improved compared with previous work. The conclusion of a finite lifetime drawn there cannot be confirmed with the present data. In addition, the lifetime of the two states at E_x=5181 and 6172 keV have been measured with the same technique in order to verify the experimental method. We observe an attenuation factor F(tau)>0.98 for the E_x =6172 and 6792 keV states, respectively, corresponding to tau<0.77 fs. The attenuation factor for the E_x=5181 keV state results in F(tau)=0.78+/-0.02 corresponding to tau=8.4+/-1.0 fs in excellent agreement with literature., Comment: 7 pages, 9 figures, accepted for publication in PRC

Published
2008
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3. First direct measurement of the total cross section of 12C(alpha,gamma)16O

Author

Schuermann, D., Di Leva, A., Gialanella, L., Rogalla, D., Strieder, F., De Cesare, N., D'Onofrio, A., Imbriani, G., Kunz, R., Lubritto, C., Ordine, A., Roca, V., Rolfs, C., Romano, M., Schuemann, F., Terrasi, F., and Trautvetter, H. -P.

Subjects
Nuclear Experiment
Abstract

The total cross section of 12C(alpha,gamma)16O was measured for the first time by a direct and ungated detection of the 16O recoils. This measurement in inverse kinematics using the recoil mass separator ERNA in combination with a windowless He gas target allowed to collect data with high precision in the energy range E=1.9 to 4.9 MeV. The data represent new information for the determination of the astrophysical S(E) factor., Comment: 5 pages, 3 figures, 1 table, accepted for publication Eur.Phys.J. A (Online first available)

Published
2005
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7. New measurement of 7Be half-life in different metallic environments

Author

Limata, B. N., Fülöp, Zs., Schürmann, D., De Cesare, N., D’Onofrio, A., Esposito, A., Gialanella, L., Gyürky, Gy., Imbriani, G., Raiola, F., Roca, V., Rogalla, D., Rolfs, C., Romano, M., Somorjai, E., Strieder, F., Terrasi, F., Fülöp, Zsolt, editor, Gyürky, György, editor, and Somorjai, Endre, editor

Published
2006
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8. Multiorganinfektionen — komplexe klinisch-infektiologische Krankheiten

Author

Bergmann, Frank, Bienzle, Ulrich, Breithaupt, Henning, Grimminger, Friedrich, Lohmeyer, Jürgen, Schürmann, D., Seeger, Werner, Suttorp, Norbert, Walmrath, Hans-Dieter, Schölmerich, Jürgen, editor, Burdach, S., editor, Drexler, H., editor, Hallek, M., editor, Hiddemann, W., editor, Hörl, W.H., editor, Klein, H., editor, Landthaler, M., editor, Lenz, K., editor, Mann, K., editor, Mössner, J., editor, Müller-Ladner, U., editor, Reichen, J., editor, Schmiegel, W., editor, Schröder, J.O., editor, Seeger, W., editor, Stremmel, W., editor, Suttorp, N., editor, Weilemann, L.S., editor, and Wöhrle, J.C., editor

Published
2005
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9. Reisemedizinische Betreuung von HIV-Infizierten

Author

Grobusch, M. P., Weinke, T., Padberg, J., Teichmann, D., Schürmann, D., Bergmann, F., Brockmeyer, Norbert H., editor, Hoffmann, Klaus, editor, Reimann, G., editor, Stücker, Markus, editor, Altmeyer, Peter, editor, and Brodt, R., editor

Published
2000
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18. Recoil separator ERNA: acceptances in angle and energy

Author

Rogalla, D., Schürmann, D., Strieder, F., Aliotta, M., DeCesare, N., DiLeva, A., Lubritto, C., D’Onofrio, A., Gialanella, L., Imbriani, G., Kluge, J., Ordine, A., Roca, V., Röcken, H., Rolfs, C., Romano, M., Schümann, F., Terrasi, F., and Trautvetter, H.P.

Published
2003
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19. The LUNA II [formula omitted] accelerator

Author

Formicola, A., Imbriani, G., Junker, M., Bemmerer, D., Bonetti, R., Broggini, C., Casella, C., Corvisiero, P., Costantini, H., Gervino, G., Gustavino, C., Lemut, A., Prati, P., Roca, V., Rolfs, C., Romano, M., Schürmann, D., Strieder, F., Terrasi, F., Trautvetter, H.-P., and Zavatarelli, S.

Published
2003
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24. Radiochemical separation of 7Be from the cooling water of the neutron spallation source SINQ at PSI

Author

Schumann, D., Ayranov, M., Stowasser, T., Gialanella, L., di Leva, A., Romano, M., Schuermann, D., Schumann, D., Ayranov, M., Stowasser, T., Gialanella, L., di Leva, A., Romano, M., and Schuermann, D.

Abstract

7Be is a key radionuclide for investigation of several astrophysical processes and phenomena. In addition, it is used as a tracer in wear measurements. It is produced in considerable amounts in the cooling water (D2O) of the Spallation Induced Neutron Source (SINQ) facility at PSI by spallation reactions on 16O with the generated fast neutrons. A shielded ion-exchange filter containing 100 mL of the mixed-bed ion exchanger LEWATIT was installed as a bypass for the cooling water into the cooling loop of SINQ for three months. The collected activity of 7Be was in the range of several hundred GBq. Further, the 7Be was separated and purified in a hot-cell remotely-controlled using a separation system installed. With the exception of 10Be, radioactive byproducts can be neglected, so that this cooling water could serve as an ideal source for highly active 7Be-samples. The facility is capable of producing 7Be with activities up to 1 TBq per year. The 7Be sample preparation is described in detail and the possible uses are discussed. In particular some preliminary results of 7Be ion beam production are presented

Published
2017

26. PEPDar: A randomized prospective noninferiority study of ritonavir-boosted darunavir for HIV post-exposure prophylaxis

Author

Faetkenheuer, G., Jessen, H., Stoehr, A., Jung, N., Jessen, A. B., Kuemmerle, T., Berger, M., Bogner, J. R., Spinner, C. D., Stephan, C., Degen, O., Vogelmann, R., Spornraft-Ragaller, P., Schnaitmann, E., Jensen, B., Ulmer, A., Kittner, J. M., Haerter, G., Malfertheiner, P., Rockstroh, J., Knecht, G., Scholten, S., Harrer, T., Kern, W. V., Salzberger, B., Schuermann, D., Ranneberg, B., Faetkenheuer, G., Jessen, H., Stoehr, A., Jung, N., Jessen, A. B., Kuemmerle, T., Berger, M., Bogner, J. R., Spinner, C. D., Stephan, C., Degen, O., Vogelmann, R., Spornraft-Ragaller, P., Schnaitmann, E., Jensen, B., Ulmer, A., Kittner, J. M., Haerter, G., Malfertheiner, P., Rockstroh, J., Knecht, G., Scholten, S., Harrer, T., Kern, W. V., Salzberger, B., Schuermann, D., and Ranneberg, B.

Abstract

ObjectivesPEPDar compared the tolerability and safety of ritonavir-boosted darunavir (DRV/r)-based post-exposure prophylaxis (PEP) with the tolerability and safety of standard of care (SOC). The primary endpoint was the early discontinuation rate among the per-protocol population. MethodsPEPDar was an open-label, randomized, multicentre, prospective, noninferiority safety study. Subjects were stratified by type of event (occupational vs. nonoccupational, i.e. sexual) and were randomized to receive DRV/r plus two nucleoside reverse transcriptase inhibitors (NRTIs) or SOC PEP. Twenty-two private or university HIV clinics in Germany participated. Subjects were 18 years old and had documented or potential HIV exposure and indication for HIV PEP. They initiated PEP not later than 72 h after the event and were HIV negative. ResultsA total of 324 subjects were screened, the per-protocol population was 305, and 273 subjects completed the study. One hundred and fifty-five subjects received DRV/r-based PEP and 150 subjects received ritonavir-boosted lopinavir (LPV/r)-based PEP for 28-30 days; 298 subjects also received tenofovir/emtricitabine. The early discontinuation rate in the DRV/r arm was 6.5% compared with 10.0% in the SOC arm (P = 0.243). Adverse drug reactions (ADRs) were reported in 68% of DRV/r subjects and 75% of SOC subjects (P = 0.169). Fewer DRV/r subjects (16.1%) had at least one grade 2 or 3 ADR compared with SOC subjects (29.3%) (P = 0.006). All grades of diarrhoea, nausea, and sleep disorders were significantly less frequent with DRV/r, while headache was significantly more frequent. No HIV seroconversion was reported during follow-up. ConclusionsNoninferiority of DRV/r to SOC was demonstrated. DRV/r should be included as a standard component of recommended regimens in PEP guidelines.

Published
2016

27. Stellar and Primordial Nucleosynthesis of 7Be: Measurement of 3He(α,γ)7Be

Author

DI LEVA, ANTONINO, IMBRIANI, GIANLUCA, ROCA, VINCENZO, ROMANO, MARIO, Gialanella L., Kunz R., Rogalla D., Schuermann D., Strieder F., de Cesare M., de Cesare N., D'Onofrio A., Fulop Z., Gyurky G., Mangano G., Ordine A., Rolfs C., Somorjai E., Terrasi F., DI LEVA, Antonino, Gialanella, L., Kunz, R., Rogalla, D., Schuermann, D., Strieder, F., de Cesare, M., de Cesare, N., D'Onofrio, A., Fulop, Z., Gyurky, G., Imbriani, Gianluca, Mangano, G., Ordine, A., Roca, Vincenzo, Rolfs, C., Romano, Mario, Somorjai, E., and Terrasi, F.

Subjects
Nuclear astrophysic, stellar evolution, experimental nuclear physic
Abstract

The 3He(α,γ)7Be reaction presently represents the largest nuclear uncertainty in the predicted solar neutrino flux and has important implications on the big bang nucleosynthesis, i.e., the production of primordial 7Li. We present here the results of an experiment using the recoil separator ERNA (European Recoil separator for Nuclear Astrophysics) to detect directly the 7Be ejectiles. In addition, off-beam activation and coincidence γ-ray measurements were performed at selected energies. At energies above 1 MeV a large discrepancy compared to previous results is observed both in the absolute value and in the energy dependence of the cross section. Based on the available data and models, a robust estimate of the cross section at the astrophysical relevant energies is proposed.

Published
2009

29. Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA

Author

Pfaffeneder, T., Spada, F., Wagner, M., Brandmayr, C., Laube, S.K., Eisen, D., Truss, M., Steinbacher, J., Hackner, B., Kotljarova, O., Schuermann, D., Michalakis, S., Kosmatchev, O., Schiesser, S., Steigenberger, B., Raddaoui, N., Kashiwazaki, G., Muller, U., Spruijt, C.G., Vermeulen, M., Leonhardt, H., Schar, P., Muller, M., Carell, T., Pfaffeneder, T., Spada, F., Wagner, M., Brandmayr, C., Laube, S.K., Eisen, D., Truss, M., Steinbacher, J., Hackner, B., Kotljarova, O., Schuermann, D., Michalakis, S., Kosmatchev, O., Schiesser, S., Steigenberger, B., Raddaoui, N., Kashiwazaki, G., Muller, U., Spruijt, C.G., Vermeulen, M., Leonhardt, H., Schar, P., Muller, M., and Carell, T.

Abstract

Item does not contain fulltext

Published
2014

31. Study of the reaction 3He(d,α)p through the Trojan Horse Method

Author

LA COGNATA, M., Musumarra, A., Spitaleri, C, Cherubini, Silvio, DEL ZOPPO, A., Di, A., Pietro, Figuera, P., Lamia, L., Lattuada, Marcello, Pellegriti, M. G., Pappalardo, L., Pizzone, R. G., Rolfs, C., Romano, Stefano, Schuermann, D., Tumino, A., Tudisco, S., and Typel, S.

Published
2003

32. Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function

Author

Messner, S, Schuermann, D, Altmeyer, M, Kassner, I, Schmidt, D, Schär, P, Müller, S, Hottiger, M O, Messner, S, Schuermann, D, Altmeyer, M, Kassner, I, Schmidt, D, Schär, P, Müller, S, and Hottiger, M O

Abstract

Poly(ADP-ribose) polymerase 1 (PARP1) is a chromatin-associated nuclear protein and functions as a molecular stress sensor. At the cellular level, PARP1 has been implicated in a wide range of processes, such as maintenance of genome stability, cell death, and transcription. PARP1 functions as a transcriptional coactivator of nuclear factor B (NF-B) and hypoxia inducible factor 1 (HIF1). In proteomic studies, PARP1 was found to be modified by small ubiquitin-like modifiers (SUMOs). Here, we characterize PARP1 as a substrate for modification by SUMO1 and SUMO3, both in vitro and in vivo. PARP1 is sumoylated at the single lysine residue K486 within its automodification domain. Interestingly, modification of PARP1 with SUMO does not affect its ADP-ribosylation activity but completely abrogates p300-mediated acetylation of PARP1, revealing an intriguing crosstalk of sumoylation and acetylation on PARP1. Genetic complementation of PARP1-depleted cells with wildtype and sumoylation-deficient PARP1 revealed that SUMO modification of PARP1 restrains its transcriptional coactivator function and subsequently reduces gene expression of distinct PARP1-regulated target genes. Messner, S., Schuermann, D., Altmeyer, M., Kassner, I., Schmidt, D., Scha¨r, P., Mu¨ller, S., and Hottiger, M. O. Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function.

Published
2009

34. PET scans in HIV-related Hodgkin lymphoma (HIV-HL): Results of a retrospective study.

Author

Hentrich, M., primary, Berger, M., additional, Hoffmann, C., additional, Siehl, J., additional, Wolf, T., additional, Nickelsen, M., additional, Rockstroh, J., additional, Schuermann, D., additional, Rieke, A., additional, Schmidmaier, R., additional, Knechten, H., additional, Mueller, M., additional, Fätkenheuer, G., additional, Meyer, R., additional, Arastéh, K., additional, Mosthaf, F. A., additional, and Wyen, C., additional

Published
2011
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35. Comparison of metabolic abnormalities and clinical lipodystrophy 48 weeks after switching from HAART to Trizivir™ versus continued HAART: The trizal study

Author

Lafeuillade, Alain, Clumeck, Nathan, Mallolas, Josep, Jaeger, Hans, Livrozet, Jean-Michel, do Sameira Ferreira, Maria, Johnson, Margaret, Cheret, Arnaud, Antoun, Zeina, Demonty, Jean, Bazin, C., Bentata, Michelle, Bouvet, Élisabeth, Delfraissy, J.F., Dellamonica, Pierre, Saint Marc, T., De Saint Martin, Luc, De Truchis, Pierre, Dien, Georges, Gallais, H., Gil, Helder, Hoen, Bruno, Katlama, Christine, Lacoste, Denis, Lang, Jeanmarie, Beumont, Maria, Massip, P., Rozenbaum, Willy, Sereni, Daniel, Yeni, Patrick, Fenske, Stefan, Rockstroh, Jürgen, Salzberger, Bernd, Schuermann, D., Staszewski, Schlomo, Mulcahy, Fiona, Lazzarin, Adriano, Milazzo, Francesco, Moroni, Mauro, Cargnel, Antonietta, Santos, Claudia Paula, Flamholc, Leo, Koppel, Kristina, Easterbrook, Philippa, Fisher, Martin, Gazzard, Brian, Kinghorn, George, Weber, Jonathan, Wilkins, Edmund, Lafeuillade, Alain, Clumeck, Nathan, Mallolas, Josep, Jaeger, Hans, Livrozet, Jean-Michel, do Sameira Ferreira, Maria, Johnson, Margaret, Cheret, Arnaud, Antoun, Zeina, Demonty, Jean, Bazin, C., Bentata, Michelle, Bouvet, Élisabeth, Delfraissy, J.F., Dellamonica, Pierre, Saint Marc, T., De Saint Martin, Luc, De Truchis, Pierre, Dien, Georges, Gallais, H., Gil, Helder, Hoen, Bruno, Katlama, Christine, Lacoste, Denis, Lang, Jeanmarie, Beumont, Maria, Massip, P., Rozenbaum, Willy, Sereni, Daniel, Yeni, Patrick, Fenske, Stefan, Rockstroh, Jürgen, Salzberger, Bernd, Schuermann, D., Staszewski, Schlomo, Mulcahy, Fiona, Lazzarin, Adriano, Milazzo, Francesco, Moroni, Mauro, Cargnel, Antonietta, Santos, Claudia Paula, Flamholc, Leo, Koppel, Kristina, Easterbrook, Philippa, Fisher, Martin, Gazzard, Brian, Kinghorn, George, Weber, Jonathan, and Wilkins, Edmund

Abstract

SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2003

36. [636] THE INFLUENCE OF NUCLEOSIDE FREE HAART ON THE TREATMENT OF CHRONIC HEPATITIS C WITH PEGYLATED INTERFERON/RIBAVIRIN COMBINATION TREATMENT

Author

Rockstroh, J.K., primary, Ahlenstiehl, G., additional, Vogel, M., additional, Klausen, G., additional, Lutz, T., additional, Schuermann, D., additional, Carlebach, A., additional, Mayr, C., additional, Carganico, A., additional, Buggisch, P., additional, Klinker, H., additional, John, C., additional, Goelz, I., additional, and Staszewski, S., additional

Published
2007
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38. Radiochemical separation of 7Be from the cooling water of the neutron spallation source SINQ at PSI.

Author

Schumann, D., Ayranov, M., Stowasser, T., Gialanella, L., di Leva, A., Romano, M., and Schuermann, D.

Subjects
RADIOCHEMICAL analysis, SEPARATION (Technology), SPALLATION (Nuclear physics), NUCLEAR reactions, ION exchange (Chemistry)
Abstract

7Be is a key radionuclide for investigation of several astrophysical processes and phenomena. In addition, it is used as a tracer in wear measurements. It is produced in considerable amounts in the cooling water (D2O) of the Spallation Induced Neutron Source (SINQ) facility at PSI by spallation reactions on 16O with the generated fast neutrons. A shielded ion-exchange filter containing 100 mL of the mixed-bed ion exchanger LEWATIT was installed as a bypass for the cooling water into the cooling loop of SINQ for three months. The collected activity of 7Be was in the range of several hundred GBq. Further, the 7Be was separated and purified in a hot-cell remotely-controlled using a separation system installed. With the exception of 10Be, radioactive byproducts can be neglected, so that this cooling water could serve as an ideal source for highly active 7Be-samples. The facility is capable of producing 7Be with activities up to 1 TBq per year. The 7Be sample preparation is described in detail and the possible uses are discussed. In particular some preliminary results of 7Be ion beam production are presented. [ABSTRACT FROM AUTHOR]

Published
2013
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39. Radiochemical separation of 7Be from the cooling water of the neutron spallation source SINQ at PSI

Author

Schumann, D., Ayranov, M., Stowasser, T., Gialanella, L., di Leva, A., Romano, M., Schuermann, D., Schumann, D., Ayranov, M., Stowasser, T., Gialanella, L., di Leva, A., Romano, M., and Schuermann, D.

Abstract

7Be is a key radionuclide for investigation of several astrophysical processes and phenomena. In addition, it is used as a tracer in wear measurements. It is produced in considerable amounts in the cooling water (D2O) of the Spallation Induced Neutron Source (SINQ) facility at PSI by spallation reactions on 16O with the generated fast neutrons. A shielded ion-exchange filter containing 100 mL of the mixed-bed ion exchanger LEWATIT was installed as a bypass for the cooling water into the cooling loop of SINQ for three months. The collected activity of 7Be was in the range of several hundred GBq. Further, the 7Be was separated and purified in a hot-cell remotely-controlled using a separation system installed. With the exception of 10Be, radioactive byproducts can be neglected, so that this cooling water could serve as an ideal source for highly active 7Be-samples. The facility is capable of producing 7Be with activities up to 1 TBq per year. The 7Be sample preparation is described in detail and the possible uses are discussed. In particular some preliminary results of 7Be ion beam production are presented

46. 14,15N beam from cyanide compounds

Author

Di Leva, A., Pezzella, A., De Cesare, N., D'Onofrio, A., Gialanella, L., Romano, M., Romoli, M., Schuermann, D., Terrasi, F., and Imbriani, G.

Subjects
*ION bombardment, *CYANIDES, *NUCLEAR astrophysics, *SUBSTRATES (Materials science), *ATOMIC mass, *GRAPHITE
Abstract

Abstract: We report here on the direct generation of a CN− ion beam for the production of a N ion beam to be used in nuclear astrophysics measurements. The procedure relies on the production of CN− ion beam with a SNICS source starting from several appropriate substrates containing CN− triple bond. Several of the investigated substrates showed a higher beam intensity with respect to the common N beam production from a cathode of BN plus graphite. Best results in terms of analyzed beam intensity were observed with K3Fe(CN)6 and KSCN cathodes. Use of the latter compound is particularly appealing because of the easy availability of mass-15 enriched molecule. [Copyright &y& Elsevier]

Published
2012
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48. Radiochemical separation of 7Be from the cooling water of the neutron spallation source SINQ at PSI

Author

Lucio Gialanella, M. Romano, M. Ayranov, D. Schuermann, Dorothea Schumann, T. Stowasser, A. di Leva, Schumann, D., Ayranov, M., Stowasser, T., Gialanella, L., DI LEVA, Antonino, Romano, M., Schuermann, D., Gialanella, Lucio, and di Leva, A.

Subjects
Spallation reaction, Chemistry, Nuclear astrophysics, Be-7, Chemical separation techniques, Nuclear engineering, Separation (aeronautics), Water cooling, Spallation, Neutron, Physical and Theoretical Chemistry
Abstract

Radiochimica acta, 101 (8), ISSN:0033-8230, ISSN:2193-3405

Published
2013
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