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6. Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs

Author

Bousquet, J., Schünemann, H. J., Samolinski, B., Demoly, P., Baena-Cagnani, C. E., Bachert, C., Bonini, S., Boulet, L. P., Bousquet, P. J., Brozek, J. L., Canonica, G. W., Casale, T. B., Cruz, A. A., Fokkens, W. J., Fonseca, J. A., van Wijk, Gerth R., Grouse, L., Haahtela, T., Khaltaev, N., Kuna, P., Lockey, R. F., Lodrup Carlsen, K. C., Mullol, J., Naclerio, R., OʼHehir, R. E., Ohta, K., Palkonen, S., Papadopoulos, N. G., Passalacqua, G., Pawankar, R., Price, D., Ryan, D., Simons, F. E.R., Togias, A., Williams, D., Yorgancioglu, A., Yusuf, O. M., Aberer, W., Adachi, M., Agache, I., Aït-Khaled, N., Akdis, C. A., Andrianarisoa, A., Annesi-Maesano, I., Ansotegui, I. J., Baiardini, I., Bateman, E. D., Bedbrook, A., Beghé, B., Beji, M., Bel, E. H., Ben Kheder, A., Bennoor, K. S., Bergmann, K. C., Berrissoul, F., Bieber, T., Bindslev Jensen, C., Blaiss, M. S., Boner, A. L., Bouchard, J., Braido, F., Brightling, C. E., Bush, A., Caballero, F., Calderon, M. A., Calvo, M. A., Camargos, P. A.M., Caraballo, L. R., Carlsen, K. H., Carr, W., Cepeda, A. M., Cesario, A., Chavannes, N. H., Chen, Y. Z., Chiriac, A. M., Chivato Pérez, T., Chkhartishvili, E., Ciprandi, G., Costa, D. J., Cox, L., Custovic, A., Dahl, R., Darsow, U., De Blay, F., Deleanu, D., Denburg, J. A., Devillier, P., Didi, T., Dokic, D., Dolen, W. K., Douagui, H., Dubakiene, R., Durham, S. R., Dykewicz, M. S., El-Gamal, Y., El-Meziane, A., Emuzyte, R., Fiocchi, A., Fletcher, M., Fukuda, T., Gamkrelidze, A., Gereda, J. E., González Diaz, S., Gotua, M., Guzmán, M. A., Hellings, P. W., Hellquist-Dahl, B., Horak, F., Hourihane, Oʼ B.J., Howarth, P., Humbert, M., Ivancevich, J. C., Jackson, C., Just, J., Kalayci, O., Kaliner, M. A., Kalyoncu, A. F., Keil, T., Keith, P. K., Khayat, G., Kim, Y. Y., Koffi NʼGoran, B., Koppelman, G. H., Kowalski, M. L., Kull, I., Kvedariene, V., Larenas-Linnemann, D., Le, L. T., Lemière, C., Li, J., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M. J., Martin, F., Marshall, G. D., Martinez, F. D., Masjedi, M. R., Maurer, M., Mavale-Manuel, S., Mazon, A., Melen, E., Meltzer, E. O., Mendez, N. H., Merk, H., Mihaltan, F., Mohammad, Y., Morais-Almeida, M., Muraro, A., Nafti, S., Namazova-Baranova, L., Nekam, K., Neou, A., Niggemann, B., Nizankowska-Mogilnicka, E., Nyembue, T. D., Okamoto, Y., Okubo, K., Orru, M. P., Ouedraogo, S., Ozdemir, C., Panzner, P., Pali-Schöll, I., Park, H. S., Pigearias, B., Pohl, W., Popov, T. A., Postma, D. S., Potter, P., Rabe, K. F., Ratomaharo, J., Reitamo, S., Ring, J., Roberts, R., Rogala, B., Romano, A., Roman Rodriguez, M., Rosado-Pinto, J., Rosenwasser, L., Rottem, M., Sanchez-Borges, M., Scadding, G. K., Schmid-Grendelmeier, P., Sheikh, A., Sisul, J. C., Solé, D., Sooronbaev, T., Spicak, V., Spranger, O., Stein, R. T., Stoloff, S. W., Sunyer, J., Szczeklik, A., Todo-Bom, A., Toskala, E., Tremblay, Y., Valenta, R., Valero, A. L., Valeyre, D., Valiulis, A., Valovirta, E., Van Cauwenberge, P., Vandenplas, O., van Weel, C., Vichyanond, P., Viegi, G., Wang, D. Y., Wickman, M., Wöhrl, S., Wright, J., Yawn, B. P., Yiallouros, P. K., Zar, H. J., Zernotti, M. E., Zhong, N., Zidarn, M., and Zuberbier, T.

Published
2012
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8. How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA2LEN statement

Author

Bousquet, J., Schünemann, H. J., Bousquet, P. J., Bachert, C., Canonica, G. W., Casale, T. B., Demoly, P., Durham, S., Carlsen, K.-H., Malling, H.-J., Passalacqua, G., Simons, F. E. R., Anto, J., Baena-Cagnani, C. E., Bergmann, K.-C., Bieber, T., Briggs, A. H., Brozek, J., Calderon, M. A., Dahl, R., Devillier, P., Gerth van Wijk, R., Howarth, P., Larenas, D., Papadopoulos, N. G., Schmid-Grendelmeier, P., and Zuberbier, T.

Published
2011
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9. Grading quality of evidence and strength of recommendations in clinical practice guidelines Part 3 of 3. The GRADE approach to developing recommendations

Author

Brożek, J. L., Akl, E. A., Compalati, E., Kreis, J., Terracciano, L., Fiocchi, A., Ueffing, E., Andrews, J., Alonso-Coello, P., Meerpohl, J. J., Lang, D. M., Jaeschke, R., Williams, J. W., Jr, Phillips, B., Lethaby, A., Bossuyt, P., Glasziou, P., Helfand, M., Watine, J., Afilalo, M., Welch, V., Montedori, A., Abraha, I., Horvath, A. R., Bousquet, J., Guyatt, G. H., and Schünemann, H. J.

Published
2011
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10. Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper

Author

Bousquet, J., Schünemann, H. J., Zuberbier, T., Bachert, C., Baena-Cagnani, C. E., Bousquet, P. J., Brozek, J., Canonica, G. W., Casale, T. B., Demoly, P., Gerth van Wijk, R., Ohta, K., Bateman, E. D., Calderon, M., Cruz, A. A., Dolen, W. K., Haughney, J., Lockey, R. F., Lötvall, J., OʼByrne, P., Spranger, O., Togias, A., Bonini, S., Boulet, L. P., Camargos, P., Carlsen, K. H., Chavannes, N. H., Delgado, L., Durham, S. R., Fokkens, W. J., Fonseca, J., Haahtela, T., Kalayci, O., Kowalski, M. L., Larenas-Linnemann, D., Li, J., Mohammad, Y., Mullol, J., Naclerio, R., OʼHehir, R. E., Papadopoulos, N., Passalacqua, G., Rabe, K. F., Pawankar, R., Ryan, D., Samolinski, B., Simons, F. E. R., Valovirta, E., Yorgancioglu, A., Yusuf, O. M., Agache, I., Aït-Khaled, N., Annesi-Maesano, I., Beghe, B., Ben Kheder, A., Blaiss, M. S., Boakye, D. A., Bouchard, J., Burney, P. G., Busse, W. W., Chan-Yeung, M., Chen, Y., Chuchalin, A. G., Costa, D. J., Custovic, A., Dahl, R., Denburg, J., Douagui, H., Emuzyte, R., Grouse, L., Humbert, M., Jackson, C., Johnston, S. L., Kaliner, M. A., Keith, P. K., Kim, Y. Y., Klossek, J. M., Kuna, P., Le, L. T., Lemiere, C., Lipworth, B., Mahboub, B., Malo, J. L., Marshall, G. D., Mavale-Manuel, S., Meltzer, E. O., Morais-Almeida, M., Motala, C., Naspitz, C., Nekam, K., Niggemann, B., Nizankowska-Mogilnicka, E., Okamoto, Y., Orru, M. P., Ouedraogo, S., Palkonen, S., Popov, T. A., Price, D., Rosado-Pinto, J., Scadding, G. K., Sooronbaev, T. M., Stoloff, S. W., Toskala, E., van Cauwenberge, P., Vandenplas, O., van Weel, C., Viegi, G., Virchow, J. C., Wang, D. Y., Wickman, M., Williams, D., Yawn, B. P., Zar, H. J., Zernotti, M., and Zhong, N.

Published
2010
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13. GA2LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma ‘epidemic’

Author

Bousquet, J., Burney, P. G., Zuberbier, T., Cauwenberge, P. v., Akdis, C. A., Bindslev-Jensen, C., Bonini, S., Fokkens, W. J., Kauffmann, F., Kowalski, M. L., Lodrup-Carlsen, K., Mullol, J., Nizankowska-Mogilnicka, E., Papadopoulos, N., Toskala, E., Wickman, M., Anto, J., Auvergne, N., Bachert, C., Bousquet, P. J., Brunekreef, B., Canonica, G. W., Carlsen, K. H., Gjomarkaj, M., Haahtela, T., Howarth, P., Lenzen, G., Lotvall, J., Radon, K., Ring, J., Salapatas, M., Schünemann, H. J., Szczecklik, A., Todo-Bom, A., Valovirta, E., von Mutius, E., and Zock, J. P.

Published
2009
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14. Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper

Author

Bousquet, J., Fokkens, W., Burney, P., Durham, S. R., Bachert, C., Akdis, C. A., Canonica, G. W., Dahlen, S.-E., Zuberbier, T., Bieber, T., Bonini, S., Bousquet, P. J., Brozek, J. L., Cardell, L.-O., Crameri, R., Custovic, A., Demoly, P., van Wijk, R. G., Gjomarkaj, M., Holland, C., Howarth, P., Humbert, M., Johnston, S. L., Kauffmann, F., Kowalski, M. L., Lambrecht, B., Lehmann, S., Leynaert, B., Lodrup-Carlsen, K., Mullol, J., Niggemann, B., Nizankowska-Mogilnicka, E., Papadopoulos, N., Passalacqua, G., Schünemann, H. J., Simon, H.-U., Todo-Bom, A., Toskala, E., Valenta, R., Wickman, M., and Zock, J. P.

Published
2008

16. [From scientific evidence to clinical recommendations: outlooks and challenges for the SIN (Italian Society of Nephrology)]

Author

Santoro, D., Torri, E., Rigoni, M., Giandomenico Nollo, Schünemann, H. J., and Brunori, G.

Subjects
Evidence-Based Medicine, Italy, Conflict of Interest, Nephrology, Clinical Practice Guidelines, GRADE method, Italian Society of Nephrology, National Plan, International Cooperation, Clinical Decision-Making, Practice Guidelines as Topic, Societies, Medical
Abstract

According to the new Clinical Guidelines National Plan, Scientific Societies take on a key role in creating and implementing guidelines within the National Health System. We chart the efforts of our Society in creating the right kind of expertise and closing the gap with Scientific Societies abroad.

Published
2019

17. ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

Author

Bousquet, J., Bedbrook, A., Czarlewski, W., Onorato, G. L., Arnavielhe, S., Laune, D., Mathieu-Dupas, E., Fonseca, J., Costa, E., Lourenço, O., Morais-Almeida, M., Todo-Bom, A., Illario, M., Menditto, E., Canonica, G. W., Cecchi, L., Monti, R., Napoli, L., Ventura, M. T., De Feo, G., Fokkens, W. J., Chavannes, N. H., Reitsma, S., Cruz, A. A., da Silva, J., Serpa, F. S., Larenas-Linnemann, D., Fuentes-Perez, J. M., Huerta-Villalobos, Y. R., Rivero-Yeverino, D., Rodriguez-Zagal, E., Valiulis, A., Dubakiene, R., Emuzyte, R., Kvedariene, V., Annesi-Maesano, I., Blain, H., Bonniaud, P., Bosse, I., Dauvilliers, Y., Devillier, P., Fontaine, J. F., Pépin, J. L., Pham-Thi, N., Portejoie, F., Picard, R., Roche, N., Rolland, C., Schmidt-Grendelmeier, P., Kuna, P., Samolinski, B., Anto, J. M., Cardona, V., Mullol, J., Pinnock, H., Ryan, D., Sheikh, A., Walker, S., Williams, S., Becker, S., Klimek, L., Pfaar, O., Bergmann, K. C., Mösges, R., Zuberbier, T., Roller-Wirnsberger, R. E., Tomazic, P. V., Haahtela, T., Salimäki, J., Toppila-Salmi, S., Valovirta, E., Vasankari, T., Gemicioğlu, B., Yorgancioglu, A., Papadopoulos, N. G., Prokopakis, E. P., Tsiligianni, I. G., Bosnic-Anticevich, S., O’Hehir, R., Ivancevich, J. C., Neffen, H., Zernotti, M. E., Kull, I., Melén, E., Wickman, M., Bachert, C., Hellings, P. W., Brusselle, G., Palkonen, S., Bindslev-Jensen, C., Eller, E., Waserman, S., Boulet, L. P., Bouchard, J., Chu, D. K., Schünemann, H. J., Sova, M., De Vries, G., van Eerd, M., Agache, I., Ansotegui, I. J., Bewick, M., Casale, T., Dykewick, M., Ebisawa, M., Murray, R., Naclerio, R., Okamoto, Y., Wallace, D. V., Aberer, W., Akdis, C. A., Akdis, M., Aliberti, M. R., Almeida, R., Amat, F., Angles, R., Arnavielle, S., Asayag, E., Asarnoj, A., Arshad, H., Avolio, F., Bacci, E., Baiardini, I., Barbara, C., Barbagallo, M., Baroni, I., Barreto, B. A., Basagana, X., Bateman, E. D., Bedolla-Barajas, M., Beghé, B., Bel, E. H., Bennoor, K. S., Benson, M., Bertorello, L., Białoszewski, A. Z., Bieber, T., Bialek, S., Bjermer, L., Blasi, F., Blua, A., Bochenska Marciniak, M., Bogus-Buczynska, I., Boner, A. L., Bonini, M., Bonini, S., Bosnic-Anticevich, C. S., Bourret, R., Bousquet, P. J., Braido, F., Briedis, V., Brightling, C. E., Brozek, J., Bucca, C., Buhl, R., Buonaiuto, R., Panaitescu, C., Burguete Cabañas, M. T., Burte, E., Bush, A., Caballero-Fonseca, F., Caillaud, D., Caimmi, D., Calderon, M. A., Camargos, P. A. M., Camuzat, T., Canfora, G., Carlsen, K. H., Carreiro-Martins, P., Carriazo, A. M., Carr, W., Cartier, C., Castellano, G., Cepeda, A. M., Chen, Y., Chiron, R., Chivato, T., Chkhartishvili, E., Chuchalin, A. G., Chung, K. F., Ciaravolo, M. M., Ciceran, A., Cingi, C., Ciprandi, G., Carvalho Coehlo, A. C., Colas, L., Colgan, E., Coll, J., Conforti, D., de Sousa, J. Correia, Cortés-Grimaldo, R. M., Corti, F., Costa-Dominguez, M. C., Courbis, A. L., Cox, L., Crescenzo, M., Custovic, A., Dahlen, S. E., D’Amato, G., Dario, C., Darsow, U., De Blay, F., De Carlo, G., Dedeu, T., de Fátima Emerson, M., De Martino, B., Motta Rubina, N. P., Deleanu, D., Demoly, P., Denburg, J. A., Di Capua Ercolano, S., Di Carluccio, N., Didier, A., Dokic, D., Dominguez-Silva, M. G., Douagui, H., Dray, G., Durham, S. R., Du Toit, G., Dykewicz, M. S., El-Gamal, Y., Eklund, P., Farrell, J., Farsi, A., Ferreira de Mello, J., Ferrero, J., Fink-Wagner, A., Fiocchi, A., Fonseca, J. A., Forti, S., Gálvez-Romero, J. L., Gamkrelidze, A., Garcia-Aymerich, J., García-Cobas, C. Y., Garcia-Cruz, M. H., Genova, S., Christoff, G., Gereda, J. E., Gerth van Wijk, R., Gomez, R. M., Gómez-Vera, J., González Diaz, S., Gotua, M., Grisle, I., Guidacci, M., Guldemond, N. A., Gutter, Z., Guzmán, M. A., Hajjam, J., Hernández, L., Hourihane, J. O’. B., Humbert, M., Iaccarino, G., Ispayeva, Z., Jares, E. J., Jassem, E., Johnston, S. L., Joos, G., Jung, K. S., Just, J., group, The MASK study, University of Helsinki, Department of Dermatology, Allergology and Venereology, University of Helsinki, Department of Pathology, University of Helsinki, Viikki science library (-2009), and University of Helsinki, Institute of Biotechnology

Subjects
3121 Internal medicine
Abstract

Mobile Airways Sentinel NetworK (MASK) belongs to the Fondation Partenariale MACVIA-LR of Montpellier, France and aims to provide an active and healthy life to rhinitis sufferers and to those with asthma multimorbidity across the life cycle, whatever their gender or socio-economic status, in order to reduce health and social inequities incurred by the disease and to improve the digital transformation of health and care. The ultimate goal is to change the management strategy in chronic diseases.

Published
2019

18. Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

Author

Bousquet, J., Bedbrook, A., Czarlewski, W., Onorato, G. L., Arnavielhe, S., Laune, D., Mathieu-Dupas, E., Fonseca, J., Costa, E., Lourenço, O., Morais-Almeida, M., Todo-Bom, A., Illario, M., Menditto, E., Canonica, G. W., Cecchi, L., Monti, R., Napoli, L., Ventura, M. T., De Feo, G., Fokkens, W. J., Chavannes, N. H., Reitsma, S., Cruz, A. A., Da Silva, J., Serpa, F. S., Larenas-Linnemann, D., Fuentes Perez, J. M., Huerta-Villalobos, Y. R., Rivero-Yeverino, D., Rodriguez-Zagal, E., Valiulis, A., Dubakiene, R., Emuzyte, R., Kvedariene, V., Annesi-Maesano, I., Blain, H., Bonniaud, P., Bosse, I., Dauvilliers, Y., Devillier, P., Fontaine, J. F., Pépin, J. L., Pham-Thi, N., Portejoie, F., Picard, R., Roche, N., Rolland, C., Schmidt-Grendelmeier, P., Kuna, P., Samolinski, B., Anto, J. M., Cardona, V., Mullol, J., Pinnock, H., Ryan, D., Sheikh, A., Walker, S., Williams, S., Becker, S., Klimek, L., Pfaar, O., Bergmann, K. C., Mösges, R., Zuberbier, T., Roller-Wirnsberger, R. E., Tomazic, P. V., Haahtela, T., Salimäki, J., Toppila-Salmi, S., Valovirta, E., Vasankari, T., Gemicioǧlu, B., Yorgancioglu, A., Papadopoulos, N. G., Prokopakis, E. P., Tsiligianni, I. G., Bosnic-Anticevich, S., O'Hehir, R., Ivancevich, J. C., Neffen, H., Zernotti, M. E., Kull, I., Melén, E., Wickman, M., Bachert, C., Hellings, P. W., Brusselle, G., Palkonen, S., Bindslev-Jensen, C., Eller, E., Waserman, S., Boulet, L. P., Bouchard, J., Chu, D. K., Schünemann, H. J., Sova, M., De Vries, G., Van Eerd, M., Agache, I., Ansotegui, I. J., Bewick, M., Casale, T., Dykewick, M., Ebisawa, M., Murray, R., Naclerio, R., Okamoto, Y., Wallace, D. V., Aberer, W., Akdis, C. A., Akdis, M., Aliberti, M. R., Almeida, R., Amat, F., Angles, R., Arnavielle, S., Asayag, E., Asarnoj, A., Arshad, H., Avolio, F., Bacci, E., Baiardini, I., Barbara, C., Barbagallo, M., Baroni, I., Barreto, B. A., Basagana, X., Bateman, E. D., Bedolla-Barajas, M., Beghé, B., Bel, E. H., Bennoor, K. S., Benson, M., Bertorello, L., Białoszewski, A. Z., Bieber, T., Bialek, S., Bjermer, L., Blasi, F., Blua, A., Bochenska Marciniak, M., Bogus-Buczynska, I., Boner, A. L., Bonini, M., Bonini, S., Bosnic-Anticevich, C. S., Bourret, R., Bousquet, P. J., Braido, F., Briedis, V., Brightling, C. E., Brozek, J., Bucca, C., Buhl, R., Buonaiuto, R., Panaitescu, C., Burguete Cabañas, M. T., Burte, E., Bush, A., Caballero-Fonseca, F., Caillaud, D., Caimmi, D., Calderon, M. A., Camargos, P. A. M., Camuzat, T., Canfora, G., Carlsen, K. H., Carreiro-Martins, P., Carriazo, A. M., Carr, W., Cartier, C., Castellano, G., Cepeda, A. M., Chen, Y., Chiron, R., Chivato, T., Chkhartishvili, E., Chuchalin, A. G., Chung, K. F., Ciaravolo, M. M., Ciceran, A., Cingi, C., Ciprandi, G., Carvalho Coehlo, A. C., Colas, L., Colgan, E., Coll, J., Conforti, D., De Sousa, J. Correia, Cortés-Grimaldo, R. M., Corti, F., Costa-Dominguez, M. C., Courbis, A. L., Cox, L., Crescenzo, M., Custovic, A., Dahlen, S. E., D'Amato, G., Dario, C., Darsow, U., De Blay, F., De Carlo, G., Dedeu, T., De Fátima Emerson, M., De Martino, B., Motta Rubina, N. P., Deleanu, D., Demoly, P., Denburg, J. A., Di Capua Ercolano, S., Di Carluccio, N., Didier, A., Dokic, D., Dominguez-Silva, M. G., Douagui, H., Dray, G., Durham, S. R., Du Toit, G., Dykewicz, M. S., El-Gamal, Y., Eklund, P., Farrell, J., Farsi, A., Ferreira De Mello, J., Ferrero, J., Fink-Wagner, A., Fiocchi, A., Fonseca, J. A., Forti, S., Fuentes-Perez, J. M., Gálvez-Romero, J. L., Gamkrelidze, A., Garcia-Aymerich, J., García-Cobas, C. Y., Garcia-Cruz, M. H., Genova, S., Christoff, G., Gereda, J. E., Gerth Van Wijk, R., Gomez, R. M., Gómez-Vera, J., González Diaz, S., Gotua, M., Grisle, I., Guidacci, M., Guldemond, N. A., Gutter, Z., Guzmán, M. A., Hajjam, J., Hernández, L., Hourihane, J. O. B., Humbert, M., Iaccarino, G., Ispayeva, Z., Jares, E. J., Jassem, E., Johnston, S. L., Joos, G., Jung, K. S., Just, J., Jutel, M., Kaidashev, I., Kalayci, O., Kalyoncu, A. F., Karjalainen, J., Kardas, P., Keil, T., Keith, P. K., Khaitov, M., Khaltaev, N., Kleine-Tebbe, J., Kowalski, M. L., Kuitunen, M., Kupczyk, M., Krzych-Fałta, E., Lacwik, P., Lauri, D., Lavrut, J., L. T. T., Le, Lessa, M., Levato, G., Li, J., Lieberman, P., Lipiec, A., Lipworth, B., Lodrup Carlsen, K. C., Louis, R., Luna-Pech, J. A., Magnan, A., Mahboub, B., Maier, D., Mair, A., Majer, I., Malva, J., Mandajieva, E., Manning, P., De Manuel Keenoy, E., Marshall, G. D., Masjedi, M. R., Maspero, J. F., Matta Campos, J. J., Matos, A. L., Maurer, M., Mavale-Manuel, S., Mayora, O., Medina-Avalos, M. A., Melo-Gomes, E., Meltzer, E. O., Mercier, J., Miculinic, N., Mihaltan, F., Milenkovic, B., Moda, G., Mogica-Martinez, M. D., Mohammad, Y., Momas, I., Montefort, S., Mora Bogado, D., Morato-Castro, F. F., Mota-Pinto, A., Moura Santo, P., Münter, L., Muraro, A., Nadif, R., Nalin, M., Namazova-Baranova, L., Niedeberger, V., Nekam, K., Neou, A., Nieto, A., Nogueira-Silva, L., Nogues, M., Novellino, E., Nyembue, T. D., O'Hehir, R. E., Odzhakova, C., Ohta, K., Okubo, K., Ortega Cisneros, M., Ouedraogo, S., Pali-Schöll, I., Panzner, P., Park, H. S., Papi, A., Passalacqua, G., Paulino, E., Pawankar, R., Pedersen, S., Pereira, A. M., Persico, M., Phillips, J., Pigearias, B., Pin, I., Pitsios, C., Plavec, D., Pohl, W., Popov, T. A., Potter, P., Pozzi, A. C., Price, D., Puy, R., Pugin, B., Pulido Ross, R. E., Przemecka, M., Rabe, K. F., Raciborski, F., Rajabian-Soderlund, R., Ribeirinho, I., Rimmer, J., Rizzo, J. A., Rizzo, M. C., Robalo-Cordeiro, C., Rodenas, F., Rodo, X., Rodriguez Gonzalez, M., Rodriguez-Mañas, L., Rodrigues Valle, S., Roman Rodriguez, M., Romano, A., Rolla, G., Romano, M., Rosado-Pinto, J., Rosario, N., Rottem, M., Sagara, H., Sanchez-Borges, M., Sastre-Dominguez, J., Scadding, G. K., Schunemann, H. J., Scichilone, N., Schmid-Grendelmeier, P., Shamai, S., Sierra, M., Simons, F. E. R., Siroux, V., Sisul, J. C., Skrindo, I., Solé, D., Somekh, D., Sondermann, M., Sooronbaev, T., Sorensen, M., Sorlini, M., Spranger, O., Stellato, C., Stelmach, R., Stukas, R., Sunyer, J., Strozek, J., Szylling, A., Tebyriçá, J. N., Thibaudon, M., To, T., Trama, U., Triggiani, M., Suppli Ulrik, C., Urrutia-Pereira, M., Valenta, R., Valero, A., Van Ganse, E., Van Hague, M., Vandenplas, O., Vezzani, G., Vatrella, A., Verissimo, M. T., Viart, F., Viegi, G., Vicheva, D., Vontetsianos, T., Wagenmann, M., Wallace, D., Wang, D. Y., Werfel, T., Westman, M., Williams, D. 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MINES ALES), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), uBibliorum, Bousquet J., Bedbrook A., Czarlewski W., Onorato G.L., Arnavielhe S., Laune D., Mathieu-Dupas E., Fonseca J., Costa E., Lourenco O., Morais-Almeida M., Todo-Bom A., Illario M., Menditto E., Canonica G.W., Cecchi L., Monti R., Napoli L., Ventura M.T., De Feo G., Fokkens W.J., Chavannes N.H., Reitsma S., Cruz A.A., Da Silva J., Serpa F.S., Larenas-Linnemann D., Fuentes Perez J.M., Huerta-Villalobos Y.R., Rivero-Yeverino D., Rodriguez-Zagal E., Valiulis A., Dubakiene R., Emuzyte R., Kvedariene V., Annesi-Maesano I., Blain H., Bonniaud P., Bosse I., Dauvilliers Y., Devillier P., Fontaine J.F., Pepin J.L., Pham-Thi N., Portejoie F., Picard R., Roche N., Rolland C., Schmidt-Grendelmeier P., Kuna P., Samolinski B., Anto J.M., Cardona V., Mullol J., Pinnock H., Ryan D., Sheikh A., Walker S., Williams S., Becker S., Klimek L., Pfaar O., Bergmann K.C., Mosges R., Zuberbier T., Roller-Wirnsberger 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H., Dray G., Durham S.R., Du Toit G., Dykewicz M.S., El-Gamal Y., Eklund P., Farrell J., Farsi A., Ferreira De Mello J., Ferrero J., Fink-Wagner A., Fiocchi A., Forti S., Fuentes-Perez J.M., Galvez-Romero J.L., Gamkrelidze A., Garcia-Aymerich J., Garcia-Cobas C.Y., Garcia-Cruz M.H., Genova S., Christoff G., Gereda J.E., Gerth Van Wijk R., Gomez R.M., Gomez-Vera J., Gonzalez Diaz S., Gotua M., Grisle I., Guidacci M., Guldemond N.A., Gutter Z., Guzman M.A., Hajjam J., Hernandez L., Hourihane J.O.B., Humbert M., Iaccarino G., Ispayeva Z., Jares E.J., Jassem E., Johnston S.L., Joos G., Jung K.S., Just J., Jutel M., Kaidashev I., Kalayci O., Kalyoncu A.F., Karjalainen J., Kardas P., Keil T., Keith P.K., Khaitov M., Khaltaev N., Kleine-Tebbe J., Kowalski M.L., Kuitunen M., Kupczyk M., Krzych-Falta E., Lacwik P., Lauri D., Lavrut J., Le L.T.T., Lessa M., Levato G., Li J., Lieberman P., Lipiec A., Lipworth B., Lodrup Carlsen K.C., Louis R., Luna-Pech J.A., Magnan A., Mahboub B., Maier D., Mair A., Majer I., Malva J., Mandajieva E., Manning P., De Manuel Keenoy E., Marshall G.D., Masjedi M.R., Maspero J.F., Matta Campos J.J., Matos A.L., Maurer M., Mavale-Manuel S., Mayora O., Medina-Avalos M.A., Melo-Gomes E., Meltzer E.O., Mercier J., Miculinic N., Mihaltan F., Milenkovic B., Moda G., Mogica-Martinez M.D., Mohammad Y., Momas I., Montefort S., Mora Bogado D., Morato-Castro F.F., Mota-Pinto A., Moura Santo P., Munter L., Muraro A., Nadif R., Nalin M., Namazova-Baranova L., Niedeberger V., Nekam K., Neou A., Nieto A., Nogueira-Silva L., Nogues M., Novellino E., Nyembue T.D., Odzhakova C., Ohta K., Okubo K., Ortega Cisneros M., Ouedraogo S., Pali-Scholl I., Panzner P., Park H.S., Papi A., Passalacqua G., Paulino E., Pawankar R., Pedersen S., Pereira A.M., Persico M., Phillips J., Pigearias B., Pin I., Pitsios C., Plavec D., Pohl W., Popov T.A., Potter P., Pozzi A.C., Price D., Puy R., Pugin B., Pulido Ross R.E., Przemecka M., Rabe K.F., Raciborski F., Rajabian-Soderlund R., 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Zhong N., Zhanat I., Zidarn M., Zubrinich C., Zurkuhlen A., Bousquet, J., Bedbrook, A., Czarlewski, W., Onorato, G. L., Arnavielhe, S., Laune, D., Mathieu-Dupas, E., Fonseca, J., Costa, E., Lourenco, O., Morais-Almeida, M., Todo-Bom, A., Illario, M., Menditto, E., Canonica, G. W., Cecchi, L., Monti, R., Napoli, L., Ventura, M. T., De Feo, G., Fokkens, W. J., Chavannes, N. H., Reitsma, S., Cruz, A. A., Da Silva, J., Serpa, F. S., Larenas-Linnemann, D., Fuentes Perez, J. M., Huerta-Villalobos, Y. R., Rivero-Yeverino, D., Rodriguez-Zagal, E., Valiulis, A., Dubakiene, R., Emuzyte, R., Kvedariene, V., Annesi-Maesano, I., Blain, H., Bonniaud, P., Bosse, I., Dauvilliers, Y., Devillier, P., Fontaine, J. F., Pepin, J. L., Pham-Thi, N., Portejoie, F., Picard, R., Roche, N., Rolland, C., Schmidt-Grendelmeier, P., Kuna, P., Samolinski, B., Anto, J. M., Cardona, V., Mullol, J., Pinnock, H., Ryan, D., Sheikh, A., Walker, S., Williams, S., Becker, S., Klimek, L., Pfaar, O., Bergmann, K. C., Mosges, R., Zuberbier, T., Roller-Wirnsberger, R. E., Tomazic, P. V., Haahtela, T., Salimaki, J., Toppila-Salmi, S., Valovirta, E., Vasankari, T., Gemicioglu, B., Yorgancioglu, A., Papadopoulos, N. G., Prokopakis, E. P., Tsiligianni, I. G., Bosnic-Anticevich, S., O'Hehir, R., Ivancevich, J. C., Neffen, H., Zernotti, M. E., Kull, I., Melen, E., Wickman, M., Bachert, C., Hellings, P. W., Brusselle, G., Palkonen, S., Bindslev-Jensen, C., Eller, E., Waserman, S., Boulet, L. P., Bouchard, J., Chu, D. K., Schunemann, H. J., Sova, M., De Vries, G., Van Eerd, M., Agache, I., Ansotegui, I. J., Bewick, M., Casale, T., Dykewick, M., Ebisawa, M., Murray, R., Naclerio, R., Okamoto, Y., Wallace, D. V., Aberer, W., Akdis, C. A., Akdis, M., Aliberti, M. R., Almeida, R., Amat, F., Angles, R., Arnavielle, S., Asayag, E., Asarnoj, A., Arshad, H., Avolio, F., Bacci, E., Baiardini, I., Barbara, C., Barbagallo, M., Baroni, I., Barreto, B. A., Basagana, X., Bateman, E. D., Bedolla-Barajas, M., Beghe, B., Bel, E. H., Bennoor, K. 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E., D'Amato, G., Dario, C., Darsow, U., De Blay, F., De Carlo, G., Dedeu, T., De Fatima Emerson, M., De Martino, B., Motta Rubina, N. P., Deleanu, D., Demoly, P., Denburg, J. A., Di Capua Ercolano, S., Di Carluccio, N., Didier, A., Dokic, D., Dominguez-Silva, M. G., Douagui, H., Dray, G., Durham, S. R., Du Toit, G., Dykewicz, M. S., El-Gamal, Y., Eklund, P., Farrell, J., Farsi, A., Ferreira De Mello, J., Ferrero, J., Fink-Wagner, A., Fiocchi, A., Fonseca, J. A., Forti, S., Fuentes-Perez, J. M., Galvez-Romero, J. L., Gamkrelidze, A., Garcia-Aymerich, J., Garcia-Cobas, C. Y., Garcia-Cruz, M. H., Genova, S., Christoff, G., Gereda, J. E., Gerth Van Wijk, R., Gomez, R. M., Gomez-Vera, J., Gonzalez Diaz, S., Gotua, M., Grisle, I., Guidacci, M., Guldemond, N. A., Gutter, Z., Guzman, M. A., Hajjam, J., Hernandez, L., Hourihane, J. O. B., Humbert, M., Iaccarino, G., Ispayeva, Z., Jares, E. J., Jassem, E., Johnston, S. L., Joos, G., Jung, K. S., Just, J., Jutel, M., Kaidashev, I., Kalayci, O., Kalyoncu, A. F., Karjalainen, J., Kardas, P., Keil, T., Keith, P. K., Khaitov, M., Khaltaev, N., Kleine-Tebbe, J., Kowalski, M. L., Kuitunen, M., Kupczyk, M., Krzych-Falta, E., Lacwik, P., Lauri, D., Lavrut, J., Le, L. T. T., Lessa, M., Levato, G., Li, J., Lieberman, P., Lipiec, A., Lipworth, B., Lodrup Carlsen, K. C., Louis, R., Luna-Pech, J. A., Magnan, A., Mahboub, B., Maier, D., Mair, A., Majer, I., Malva, J., Mandajieva, E., Manning, P., De Manuel Keenoy, E., Marshall, G. D., Masjedi, M. R., Maspero, J. F., Matta Campos, J. J., Matos, A. L., Maurer, M., Mavale-Manuel, S., Mayora, O., Medina-Avalos, M. A., Melo-Gomes, E., Meltzer, E. O., Mercier, J., Miculinic, N., Mihaltan, F., Milenkovic, B., Moda, G., Mogica-Martinez, M. D., Mohammad, Y., Momas, I., Montefort, S., Mora Bogado, D., Morato-Castro, F. 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M., Wilson, N., Wright, J., Wroczynski, P., Yakovliev, P., Yawn, B. P., Yiallouros, P. K., Yusuf, O. M., Zar, H. J., Zhang, L., Zhong, N., Zhanat, I., Zidarn, M., Zubrinich, C., Zurkuhlen, A., UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, and UCL - (MGD) Service de pneumologie

Subjects
SENTINEL NETWORK, Allergy, Respiratory Medicine and Allergy, Review, WORLD-HEALTH-ORGANIZATION, Disease, Rhinitis, App, Asthma, Care pathways, DG Santé, MASK, mHealth, 0302 clinical medicine, QUALITY-OF-LIFE, PRECISION MEDICINE, Health care, Medicine and Health Sciences, GRADING QUALITY, Immunology and Allergy, Medicine, Rinitis, Lungmedicin och allergi, 0303 health sciences, The MASK study group, Public sector, DG Sante, MOBILE TECHNOLOGY, 3. Good health, ALLERGIC RHINITIS, CHRONIC RESPIRATORY-DISEASES, Rinite, EUROPEAN SYMPOSIUM, CLINICAL-PRACTICE GUIDELINES, Life Sciences & Biomedicine, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Immunology, Settore MED/10 - Malattie Dell'Apparato Respiratorio, Predictive medicine, 03 medical and health sciences, Quality of life (healthcare), App -MASK, Asma, 030304 developmental biology, ARIA, Science & Technology, Care pathway, business.industry, Change management, Correction, RC581-607, medicine.disease, 030228 respiratory system, Family medicine, Immunologic diseases. Allergy, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

AIMS: Mobile Airways Sentinel NetworK (MASK) belongs to the Fondation Partenariale MACVIA-LR of Montpellier, France and aims to provide an active and healthy life to rhinitis sufferers and to those with asthma multimorbidity across the life cycle, whatever their gender or socio-economic status, in order to reduce health and social inequities incurred by the disease and to improve the digital transformation of health and care. The ultimate goal is to change the management strategy in chronic diseases. METHODS: MASK implements ICT technologies for individualized and predictive medicine to develop novel care pathways by a multi-disciplinary group centred around the patients. STAKEHOLDERS: Include patients, health care professionals (pharmacists and physicians), authorities, patient's associations, private and public sectors. RESULTS: MASK is deployed in 23 countries and 17 languages. 26,000 users have registered. EU GRANTS 2018: MASK is participating in EU projects (POLLAR: impact of air POLLution in Asthma and Rhinitis, EIT Health, DigitalHealthEurope, Euriphi and Vigour). LESSONS LEARNT: (i) Adherence to treatment is the major problem of allergic disease, (ii) Self-management strategies should be considerably expanded (behavioural), (iii) Change management is essential in allergic diseases, (iv) Education strategies should be reconsidered using a patient-centred approach and (v) Lessons learnt for allergic diseases can be expanded to chronic diseases. ispartof: CLINICAL AND TRANSLATIONAL ALLERGY vol:9 issue:1 ispartof: location:England status: published

Published
2019

23. Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.

Author

UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (MGD) Service de pneumologie, Bewick, M, The MASK study group, Wallace, D V, Okamoto, Y, Naclerio, R, Murray, R, Ebisawa, M, Dykewick, M, Casale, T, Vandenplas, Olivier, Bousquet, J, Bedbrook, A, Czarlewski, W, Onorato, G L, Arnavielhe, S, Laune, D, Mathieu-Dupas, E, Fonseca, J, Costa, E, Lourenço, O, Morais-Almeida, M, Todo-Bom, A, Illario, M, Menditto, E, Canonica, G W, Cecchi, L, Monti, R, Napoli, L, Ventura, M T, De Feo, G, Fokkens, W J, Chavannes, N H, Reitsma, S, Cruz, A A, da Silva, J, Serpa, F S, Larenas-Linnemann, D, Fuentes Perez, J M, Huerta-Villalobos, Y R, Rivero-Yeverino, D, Rodriguez-Zagal, E, Valiulis, A, Dubakiene, R, Emuzyte, R, Kvedariene, V, Annesi-Maesano, I, Blain, H, Bonniaud, P, Bosse, I, Dauvilliers, Y, Devillier, P, Fontaine, J F, Pépin, J L, Pham-Thi, N, Portejoie, F, Picard, R, Roche, N, Rolland, C, Schmidt-Grendelmeier, P, Kuna, P, Samolinski, B, Anto, J M, Cardona, V, Mullol, J, Pinnock, H, Ryan, D, Sheikh, A, Walker, S, Williams, S, Becker, S, Klimek, L, Pfaar, O, Bergmann, K C, Mösges, R, Zuberbier, T, Roller-Wirnsberger, R E, Tomazic, P V, Haahtela, T, Salimäki, J, Toppila-Salmi, S, Valovirta, E, Vasankari, T, Gemicioğlu, B, Yorgancioglu, A, Papadopoulos, N G, Prokopakis, E P, Tsiligianni, I G, Bosnic-Anticevich, S, O'Hehir, R, Ivancevich, J C, Neffen, H, Zernotti, M E, Kull, I, Melén, E, Wickman, M, Bachert, C, Hellings, P W, Brusselle, G, Palkonen, S, Bindslev-Jensen, C, Eller, E, Waserman, S, Boulet, L P, Bouchard, J, Chu, D K, Schünemann, H J, Sova, M, De Vries, G, van Eerd, M, Agache, I, Ansotegui, I J, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (MGD) Service de pneumologie, Bewick, M, The MASK study group, Wallace, D V, Okamoto, Y, Naclerio, R, Murray, R, Ebisawa, M, Dykewick, M, Casale, T, Vandenplas, Olivier, Bousquet, J, Bedbrook, A, Czarlewski, W, Onorato, G L, Arnavielhe, S, Laune, D, Mathieu-Dupas, E, Fonseca, J, Costa, E, Lourenço, O, Morais-Almeida, M, Todo-Bom, A, Illario, M, Menditto, E, Canonica, G W, Cecchi, L, Monti, R, Napoli, L, Ventura, M T, De Feo, G, Fokkens, W J, Chavannes, N H, Reitsma, S, Cruz, A A, da Silva, J, Serpa, F S, Larenas-Linnemann, D, Fuentes Perez, J M, Huerta-Villalobos, Y R, Rivero-Yeverino, D, Rodriguez-Zagal, E, Valiulis, A, Dubakiene, R, Emuzyte, R, Kvedariene, V, Annesi-Maesano, I, Blain, H, Bonniaud, P, Bosse, I, Dauvilliers, Y, Devillier, P, Fontaine, J F, Pépin, J L, Pham-Thi, N, Portejoie, F, Picard, R, Roche, N, Rolland, C, Schmidt-Grendelmeier, P, Kuna, P, Samolinski, B, Anto, J M, Cardona, V, Mullol, J, Pinnock, H, Ryan, D, Sheikh, A, Walker, S, Williams, S, Becker, S, Klimek, L, Pfaar, O, Bergmann, K C, Mösges, R, Zuberbier, T, Roller-Wirnsberger, R E, Tomazic, P V, Haahtela, T, Salimäki, J, Toppila-Salmi, S, Valovirta, E, Vasankari, T, Gemicioğlu, B, Yorgancioglu, A, Papadopoulos, N G, Prokopakis, E P, Tsiligianni, I G, Bosnic-Anticevich, S, O'Hehir, R, Ivancevich, J C, Neffen, H, Zernotti, M E, Kull, I, Melén, E, Wickman, M, Bachert, C, Hellings, P W, Brusselle, G, Palkonen, S, Bindslev-Jensen, C, Eller, E, Waserman, S, Boulet, L P, Bouchard, J, Chu, D K, Schünemann, H J, Sova, M, De Vries, G, van Eerd, M, Agache, I, and Ansotegui, I J

Abstract

Mobile Airways Sentinel NetworK (MASK) belongs to the Fondation Partenariale MACVIA-LR of Montpellier, France and aims to provide an active and healthy life to rhinitis sufferers and to those with asthma multimorbidity across the life cycle, whatever their gender or socio-economic status, in order to reduce health and social inequities incurred by the disease and to improve the digital transformation of health and care. The ultimate goal is to change the management strategy in chronic diseases. MASK implements ICT technologies for individualized and predictive medicine to develop novel care pathways by a multi-disciplinary group centred around the patients. Include patients, health care professionals (pharmacists and physicians), authorities, patient's associations, private and public sectors. MASK is deployed in 23 countries and 17 languages. 26,000 users have registered. MASK is participating in EU projects (POLLAR: impact of air POLLution in Asthma and Rhinitis, EIT Health, DigitalHealthEurope, Euriphi and Vigour). (i) Adherence to treatment is the major problem of allergic disease, (ii) Self-management strategies should be considerably expanded (behavioural), (iii) Change management is essential in allergic diseases, (iv) Education strategies should be reconsidered using a patient-centred approach and (v) Lessons learnt for allergic diseases can be expanded to chronic diseases.

Published
2019

27. 2020 ARIA CARE PATHWAYS FOR ALLERGIC RHINITIS - GEORGIA.

Author

Gotua, M., Gamkrelidze, A., Rukhadze, M., Abramidze, T., Bochorishvili, E., Shengelidze, G., Dolidze, N., Chkhartishvili, E., Bachert, C., Pfaar, O., Schünemann, H. J., Zuberbier, T., Bedbrook, A., Czarlewski, W., and Bousquet, J.

Published
2019

29. NHF-McMaster Guideline on Care Models for Haemophilia Management

Author

Pai, M., primary, Key, N. S., additional, Skinner, M., additional, Curtis, R., additional, Feinstein, M., additional, Kessler, C., additional, Lane, S. J., additional, Makris, M., additional, Riker, E., additional, Santesso, N., additional, Soucie, J. M., additional, Yeung, C. H. T., additional, Iorio, A., additional, and Schünemann, H. J., additional

Published
2016
Full Text
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33. Pooling birth cohorts in allergy and asthma: European union-funded initiatives-a MeDALL, CHICOS, ENRIECO, and GALEN joint paper: CHICOS study group ENRIECO study group GA2LEN study group

Author

Bousquet, Jean, Anto, Josep, Sunyer, Jordi, Nieuwenhuijsen, Mark, Vrijheid, Martine, Keil, Thomas, Akdis, M., Auffray, C., Postma, D. S., Valenta, R., Haahtela, T., Cambon-Thomsen, A., Lambrecht, B. N., Akdis, C. A., Annesi-Maesano, I., Arno, A., Bachert, C., Ballester, F., Basagana, X., Baumgartner, U., Bindslev-Jensen, C., Brunekreef, B., Chatzi, L., Eller, E., Forastiere, F., Garcia-Aymerich, J., Guerra, S., Gehring, U., Hammad, H., Heinrich, J., Hohmann, C., Kauffmann, F., Kerkhof, M., Kogevinas, M., Koppelman, G. H., Kowalski, M. L., Kull, I., Lau, S., Lodrup-Carlsen, K. C., Lupinek, C., Maier, D., Makela, M. J., Martinez, F. D., Momas, I., Nawijn, M. C., Neubauer, A., Oddie, S., Palkonen, S., Reitamo, S., Rial-Sebbag, E., Salapatas, M., Siroux, V., Smagghe, D., Smit, H. A., Torrent, M., Toskala, E., van Oosterhout, A. J. M., Varaso, R., von Hertzen, L., Wickman, M., Wijmenga, C., Zuberbier, T., Burney, P. G., Van Cauwenberge, P., Bonini, S., Fokkens, W. J., Kramer, U., Mullol, J., Nizankowska-Mogilnicka, E., Papadopoulos, N., Alm, B., Alm, J., Arshad, S. H., Bravi, F., Canonica, G. W., Custovic, A., Dubakiene, R., Fantini, M. P., Gjomarkaj, M., Halken, S., Host, A., Howarth, P., Kuehni, C., Lotvall, J., Mommers, M., Porta, D., Radon, K., Ring, J., Roberts, G., Schünemann, H. J., Simpson, A., Szczecklik, A., Thijs, C., Todo-Bom, A., Valovirta, E., van Steen, K., Von Berg, A., von Mutius, E., Wahn, U., Wennergren, G., Wijga, A. H., Zock, J. P., Duijts, L., Jaddoe, V., Lawlor, D., Lucas, P., Magnus, P., Merletti, F., Nybo Andersen, A. M., Raat, H., Stoltenberg, C., Casas, M., Bergström, A., Carmichael, A., Chen, C. -M., Cordier, S., Eggesbø, M., Fernández, M. F., Fernández-Somoano, A., Grazuleviciene, R., Karvonen, A. M., Koppen, G., Krämer, U., Kuehni, C. E., Majewska, R., Patelarou, E., Skaalum Petersen, M., Pierik, F. H., Polanska, K., Richiardi, L., Santos, A. C., Slama, R., Sram, R. J., Tischer, C., Toft, G., Trnovec, T., Vandentorren, S., Vardavas, C., Vrijkotte, T. G. M., Wilhelm, M., Bousquet, Jean, Anto, Josep, Sunyer, Jordi, Nieuwenhuijsen, Mark, Vrijheid, Martine, Keil, Thoma, Akdis, M., Auffray, C., Postma, D.S., Valenta, R., Haahtela, T., Cambon-Thomsen, A., Lambrecht, B.N., Akdis, C.A., Annesi-Maesano, I., Arno, A., Bachert, C., Ballester, F., Basagana, X., Baumgartner, U., Bindslev-Jensen, C., Brunekreef, B., Chatzi, L., Eller, E., Forastiere, F., Garcia-Aymerich, J., Guerra, S., Gehring, U., Hammad, H., Heinrich, J., Hohmann, C., Kauffmann, F., Kerkhof, M., Kogevinas, M., Koppelman, G.H., Kowalski, M.L., Kull, I., Lau, S., Lodrup-Carlsen, K.C., Lupinek, C., Maier, D., Makela, M.J., Martinez, F.D., Momas, I., Nawijn, M.C., Neubauer, A., Oddie, S., Palkonen, S., Reitamo, S., Rial-Sebbag, E., Salapatas, M., Siroux, V., Smagghe, D., Smit, H.A., Torrent, M., Toskala, E., van Oosterhout, A.J.M., Varaso, R., von Hertzen, L., Wickman, M., Wijmenga, C., Zuberbier, T., Burney, P.G., Van Cauwenberge, P., Bonini, S., Fokkens, W.J., Kramer, U., Mullol, J., Nizankowska-Mogilnicka, E., Papadopoulos, N., Alm, B., Alm, J., Arshad, S.H., Bravi, F., Canonica, G.W., Custovic, A., Dubakiene, R., Fantini, M.P., Gjomarkaj, M., Halken, S., Host, A., Howarth, P., Kuehni, C., Lotvall, J., Mommers, M., Porta, D., Radon, K., Ring, J., Roberts, G., Schünemann, H.J., Simpson, A., Szczecklik, A., Thijs, C., Todo-Bom, A., Valovirta, E., van Steen, K., Von Berg, A., von Mutius, E., Wahn, U., Wennergren, G., Wijga, A.H., Zock, J.P., Duijts, L., Jaddoe, V., Lawlor, D., Lucas, P., Magnus, P., Merletti, F., Nybo Andersen, A.M., Raat, H., Stoltenberg, C., Casas, M., Bergström, A., Carmichael, A., Chen, C.-M., Cordier, S., Eggesbø, M., Fernández, M.F., Fernández-Somoano, A., Grazuleviciene, R., Karvonen, A.M., Koppen, G., Krämer, U., Kuehni, C.E., Majewska, R., Patelarou, E., Skaalum Petersen, M., Pierik, F.H., Polanska, K., Richiardi, L., Santos, A.C., Slama, R., Sram, R.J., Tischer, C., Toft, G., Trnovec, T., Vandentorren, S., Vardavas, C., Vrijkotte, T.G.M., and Wilhelm, M.

Subjects
Allergy, Risk Factor, Immunology, CHICOS, Longitudinal Studie, Environmental Exposure, Asthma, Europe, MeDALL, ENRIECO, Hypersensitivity, Multicenter Studies as Topic, Immunology and Allergy, European Union, Cohort Studie, Birth cohort, Human
Abstract

Long-term birth cohort studies are essential to understanding the life course and childhood predictors of allergy and the complex interplay between genes and the environment (including lifestyle and socioeconomic determinants). Over 100 cohorts focusing on asthma and allergy have been initiated in the world over the past 30 years. Since 2004, several research initiatives funded under the EU Framework Program for Research and Technological Development FP6-FP7 have attempted to identify, compare, and evaluate pooling data from existing European birth cohorts (GA2LEN: Global Allergy and European Network, FP6; ENRIECO: Environmental Health Risks in European Birth Cohorts, FP7; CHICOS: Developing a Child Cohort Research Strategy for Europe, FP7; MeDALL: Mechanisms of the Development of ALLergy, FP7). However, there is a general lack of knowledge about these initiatives and their potentials. The aim of this paper is to review current and past EU-funded projects in order to make a summary of their goals and achievements and to suggest future research needs of these European birth cohort networks. © 2012 S. Karger AG, Basel.

Published
2013

35. Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper

Author

Bousquet, J, Anto, J M, Demoly, P, Schünemann, H J, Togias, A, Akdis, M, Auffray, C, Bachert, C, Bieber, T, Bousquet, P J, Carlsen, K H, Casale, T B, Cruz, A A, Keil, T, Lodrup Carlsen, K C, Maurer, M, Ohta, K, Papadopoulos, N G, Roman Rodriguez, M, Samolinski, B, Agache, I, Andrianarisoa, A, Ang, C S, Annesi-Maesano, I, Ballester, F, Baena-Cagnani, C E, Basagaña, X, Bateman, E D, Bel, E H, Bedbrook, A, Beghé, B, Beji, M, Ben Kheder, A, Benet, M, Bennoor, K S, Bergmann, K C, Berrissoul, F, Bindslev-Jensen, Carsten, Bleecker, E R, Bonini, S, Boner, A L, Boulet, L P, Brightling, C E, Brozek, J L, Bush, A, Busse, W W, Camargos, P A M, Canonica, G W, Carr, W, Cesario, A, Groningen Research Institute of Pharmacy, Faculteit Medische Wetenschappen/UMCG, Groningen Research Institute for Asthma and COPD (GRIAC), AII - Amsterdam institute for Infection and Immunity, Pulmonology, Ear, Nose and Throat, Other Research, and Paediatric Pulmonology

Subjects
Urticaria, Rhinosinusitis, CHRONIC RHINOSINUSITIS, Comorbidity, macromolecular substances, WORLD-HEALTH-ORGANIZATION, Immunoglobulin E, Severity of Illness Index, Asthma, RANDOMIZED-TRIAL, Dermatitis, Atopic, CHRONIC URTICARIA, QUALITY-OF-LIFE, Chronic Disease, Practice Guidelines as Topic, Hypersensitivity, Humans, ATOPIC-DERMATITIS, Sinusitis, ASTHMA CONTROL QUESTIONNAIRE, NASAL POLYPOSIS, NONALLERGIC RHINITIS, Rhinitis, Atopic dermatitis, TASK-FORCE
Abstract

Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel

Published
2012

36. How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA(2) LEN statement

Author

Bousquet, J, Schünemann, H J, Bousquet, P J, Bachert, C, Canonica, G W, Casale, T B, Demoly, P, Durham, S, Malling, Hans-Jørgen, Passalacqua, G, Simons, F E R, Anto, J, Baena-Cagnani, C E, Bergmann, Rolf, Bieber, T, Briggs, A H, Brozek, J, Calderon, M A, Dahl, R, Devillier, P, Gerth van Wijk, R, Howarth, P, Larenas, D, Papadopoulos, N G, Schmid-Grendelmeier, P, Zuberbier, T, Carlsen, K. -H., and Bergmann, K. C.

Abstract

To cite this article: Bousquet J, Schünemann HJ, Bousquet PJ, Bachert C, Canonica GW, Casale TB, Demoly P, Durham S, Carlsen K-H, Malling H-J, Passalacqua G, Simons FER, Anto J, Baena-Cagnani CE, Bergmann K-C, Bieber T, Briggs AH, Brozek J, Calderon MA, Dahl R, Devillier P, Gerth van Wijk R, Howarth P, Larenas D, Papadopoulos NG, Schmid-Grendelmeier P, Zuberbier T. How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA(2) LEN statement. Allergy 2011; 66: 765-774. ABSTRACT: Specific immunotherapy (SIT) is one of the treatments for allergic rhinitis. However, for allergists, nonspecialists, regulators, payers, and patients, there remain gaps in understanding the evaluation of randomized controlled trials (RCTs). Although treating the same diseases, RCTs in SIT and pharmacotherapy should be considered separately for several reasons, as developed in this study. These include the severity and persistence of allergic rhinitis in the patients enrolled in the study, the problem of the placebo, allergen exposure (in particular pollen and mite), the analysis and reporting of the study, the level of symptoms of placebo-treated patients, the clinical relevance of the efficacy of SIT, the need for a validated combined symptom-medication score, the differences between children and adults and pharmacoeconomic analyses. This statement reviews issues raised by the interpretation of RCTs in sublingual immunotherapy. It is not possible to directly extrapolate the rules or parameters used in medication RCTs to SIT. It also provides some suggestions for the research that will be needed. Interestingly, some of the research questions can be approached with the available data obtained from large RCTs.

Published
2011

37. Adverse event assessment of antimuscarinics for treating overactive bladder: a network meta-analytic approach

Author

Kessler, T M, Bachmann, L M, Minder, C, Löhrer, D, Umbehr, M, Schünemann, H J, Kessels, A G H, and University of Zurich

Subjects
1000 Multidisciplinary, 1300 General Biochemistry, Genetics and Molecular Biology, 610 Medicine & health, 10046 Balgrist University Hospital, Swiss Spinal Cord Injury Center, 1100 General Agricultural and Biological Sciences, 10029 Clinic and Policlinic for Internal Medicine
Published
2011

38. Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper

Author

Bousquet, Jean, Schünemann, H J, Zuberbier, T, Bachert, C, Baena-Cagnani, C E, Bousquet, P J, Brozek, J, Canonica, G W, Casale, T B, Demoly, P, Gerth van Wijk, R, Ohta, K, Bateman, E D, Calderon, M, Cruz, A A, Dolen, W K, Haughney, J, Lockey, R F, Lötvall, J, O'Byrne, P, Spranger, O, Togias, A, Bonini, S, Boulet, L P, Camargos, P, Carlsen, K H, Chavannes, N H, Delgado, Lara García, Durham, S R, Fokkens, W J, Fonseca, Jun Sergio Ono, Haahtela, T, Kalayci, O, Kowalski, M L, Larenas-Linnemann, D, Li, J, Mohammad, Y, Mullol, J, Naclerio, R, O'Hehir, R E, Papadopoulos, N, Passalacqua, G, Rabe, K F, Pawankar, R, Ryan, David, Samolinski, B, Simons, F E R, Valovirta, E, Yorgancioglu, A, and Dahl, R

Subjects
Evidence-Based Medicine, Rhinitis, Allergic, Perennial, Practice Guidelines as Topic, Disease Management, Humans, Rhinitis, Allergic, Seasonal, Planning Techniques, Asthma
Abstract

The links between asthma and rhinitis are well characterized. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines stress the importance of these links and provide guidance for their prevention and treatment. Despite effective treatments being available, too few patients receive appropriate medical care for both diseases. Most patients with rhinitis and asthma consult primary care physicians and therefore these physicians are encouraged to understand and use ARIA guidelines. Patients should also be informed about these guidelines to raise their awareness of optimal care and increase control of the two related diseases. To apply these guidelines, clinicians and patients need to understand how and why the recommendations were made. The goal of the ARIA guidelines is to provide recommendations about the best management options for most patients in most situations. These recommendations should be based on the best available evidence. Making recommendations requires the assessment of the quality of available evidence, deciding on the balance between benefits and downsides, consideration of patients’ values and preferences, and, if applicable, resource implications. Guidelines must be updated as new management options become available or important new evidence emerges. Transparent reporting of guidelines facilitates understanding and acceptance, but implementation strategies need to be improved.

Published
2010

39. Integrated care pathways for airway diseases (AIRWAYS-ICPs).

Author

UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, J, Addis, A, Adcock, I, Agache, I, Agusti, A, Alonso, A, Annesi-Maesano, I, Anto, J M, Bachert, C, Baena-Cagnani, C E, Bai, C, Baigenzhin, A, Barbara, C, Barnes, P J, Bateman, E D, Beck, L, Bedbrook, A, Bel, E H, Benezet, O, Bennoor, K S, Benson, M, Bernabeu-Wittel, M, Bewick, M, Bindslev-Jensen, C, Blain, H, Blasi, F, Bonini, M, Bonini, S, Boulet, L P, Bourdin, A, Bourret, R, Bousquet, P J, Brightling, C E, Briggs, A, Brozek, J, Buhl, R, Bush, A, Caimmi, D, Calderon, M, Calverley, P, Camargos, P A, Camuzat, T, Canonica, G W, Carlsen, K H, Casale, T B, Cazzola, M, Cepeda Sarabia, A M, Cesario, A, Chen, Y Z, Chkhartishvili, E, Chavannes, N H, Chiron, R, Chuchalin, A, Chung, K F, Cox, L, Crooks, G, Crooks, M G, Cruz, A A, Custovic, A, Dahl, R, Dahlen, S E, De Blay, F, Dedeu, T, Deleanu, D, Demoly, P, Devillier, P, Didier, A, Dinh-Xuan, A T, Djukanovic, R, Dokic, D, Douagui, H, Dubakiene, R, Eglin, S, Elliot, F, Emuzyte, R, Fabbri, L, Fink Wagner, A, Fletcher, M, Fokkens, W J, Fonseca, J, Franco, A, Frith, P, Furber, A, Gaga, M, Garcés, J, Garcia-Aymerich, J, Gamkrelidze, A, Gonzales-Diaz, S, Gouzi, F, Guzmán, M A, Haahtela, T, Harrison, D, Hayot, M, Heaney, L G, Heinrich, J, Hellings, P W, Hooper, J, Humbert, M, Hyland, M, Iaccarino, G, Jakovenko, D, Jardim, J R, Jeandel, C, Jenkins, C, Johnston, S L, Jonquet, O, Joos, G, Jung, K S, Kalayci, O, Karunanithi, S, Keil, T, Khaltaev, N, Kolek, V, Kowalski, M L, Kull, I, Kuna, P, Kvedariene, V, Le, L T, Lodrup Carlsen, K C, Louis, R, MacNee, W, Mair, A, Majer, I, Manning, P, de Manuel Keenoy, E, Masjedi, M R, Melen, E, Melo-Gomes, E, Menzies-Gow, A, Mercier, G, Mercier, J, Michel, J P, Miculinic, N, Mihaltan, F, Milenkovic, B, Molimard, M, Momas, I, Montilla-Santana, A, Morais-Almeida, M, Morgan, M, N'Diaye, M, Nafti, S, Nekam, K, Neou, A, Nicod, L, O'Hehir, R, Ohta, K, Paggiaro, P, Palkonen, S, Palmer, S, Papadopoulos, N G, Papi, A, Passalacqua, G, Pavord, I, Pigearias, B, Plavec, D, Postma, D S, Price, D, Rabe, K F, Radier Pontal, F, Redon, J, Rennard, S, Roberts, J, Robine, J M, Roca, J, Roche, N, Rodenas, F, Roggeri, A, Rolland, C, Rosado-Pinto, J, Ryan, D, Samolinski, B, Sanchez-Borges, M, Schünemann, H J, Sheikh, A, Shields, M, Siafakas, N, Sibille, Yves, Similowski, T, Small, I, Sola-Morales, O, Sooronbaev, T, Stelmach, R, Sterk, P J, Stiris, T, Sud, P, Tellier, V, To, T, Todo-Bom, A, Triggiani, M, Valenta, R, Valero, A L, Valiulis, A, Valovirta, E, Van Ganse, E, Vandenplas, Olivier, Vasankari, T, Vestbo, J, Vezzani, G, Viegi, G, Visier, L, Vogelmeier, C, Vontetsianos, T, Wagstaff, R, Wahn, U, Wallaert, B, Whalley, B, Wickman, M, Williams, D M, Wilson, N, Yawn, B P, Yiallouros, P K, Yorgancioglu, A., Yusuf, O M, Zar, H J, Zhong, N, Zidarn, M, Zuberbier, T, UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, J, Addis, A, Adcock, I, Agache, I, Agusti, A, Alonso, A, Annesi-Maesano, I, Anto, J M, Bachert, C, Baena-Cagnani, C E, Bai, C, Baigenzhin, A, Barbara, C, Barnes, P J, Bateman, E D, Beck, L, Bedbrook, A, Bel, E H, Benezet, O, Bennoor, K S, Benson, M, Bernabeu-Wittel, M, Bewick, M, Bindslev-Jensen, C, Blain, H, Blasi, F, Bonini, M, Bonini, S, Boulet, L P, Bourdin, A, Bourret, R, Bousquet, P J, Brightling, C E, Briggs, A, Brozek, J, Buhl, R, Bush, A, Caimmi, D, Calderon, M, Calverley, P, Camargos, P A, Camuzat, T, Canonica, G W, Carlsen, K H, Casale, T B, Cazzola, M, Cepeda Sarabia, A M, Cesario, A, Chen, Y Z, Chkhartishvili, E, Chavannes, N H, Chiron, R, Chuchalin, A, Chung, K F, Cox, L, Crooks, G, Crooks, M G, Cruz, A A, Custovic, A, Dahl, R, Dahlen, S E, De Blay, F, Dedeu, T, Deleanu, D, Demoly, P, Devillier, P, Didier, A, Dinh-Xuan, A T, Djukanovic, R, Dokic, D, Douagui, H, Dubakiene, R, Eglin, S, Elliot, F, Emuzyte, R, Fabbri, L, Fink Wagner, A, Fletcher, M, Fokkens, W J, Fonseca, J, Franco, A, Frith, P, Furber, A, Gaga, M, Garcés, J, Garcia-Aymerich, J, Gamkrelidze, A, Gonzales-Diaz, S, Gouzi, F, Guzmán, M A, Haahtela, T, Harrison, D, Hayot, M, Heaney, L G, Heinrich, J, Hellings, P W, Hooper, J, Humbert, M, Hyland, M, Iaccarino, G, Jakovenko, D, Jardim, J R, Jeandel, C, Jenkins, C, Johnston, S L, Jonquet, O, Joos, G, Jung, K S, Kalayci, O, Karunanithi, S, Keil, T, Khaltaev, N, Kolek, V, Kowalski, M L, Kull, I, Kuna, P, Kvedariene, V, Le, L T, Lodrup Carlsen, K C, Louis, R, MacNee, W, Mair, A, Majer, I, Manning, P, de Manuel Keenoy, E, Masjedi, M R, Melen, E, Melo-Gomes, E, Menzies-Gow, A, Mercier, G, Mercier, J, Michel, J P, Miculinic, N, Mihaltan, F, Milenkovic, B, Molimard, M, Momas, I, Montilla-Santana, A, Morais-Almeida, M, Morgan, M, N'Diaye, M, Nafti, S, Nekam, K, Neou, A, Nicod, L, O'Hehir, R, Ohta, K, Paggiaro, P, Palkonen, S, Palmer, S, Papadopoulos, N G, Papi, A, Passalacqua, G, Pavord, I, Pigearias, B, Plavec, D, Postma, D S, Price, D, Rabe, K F, Radier Pontal, F, Redon, J, Rennard, S, Roberts, J, Robine, J M, Roca, J, Roche, N, Rodenas, F, Roggeri, A, Rolland, C, Rosado-Pinto, J, Ryan, D, Samolinski, B, Sanchez-Borges, M, Schünemann, H J, Sheikh, A, Shields, M, Siafakas, N, Sibille, Yves, Similowski, T, Small, I, Sola-Morales, O, Sooronbaev, T, Stelmach, R, Sterk, P J, Stiris, T, Sud, P, Tellier, V, To, T, Todo-Bom, A, Triggiani, M, Valenta, R, Valero, A L, Valiulis, A, Valovirta, E, Van Ganse, E, Vandenplas, Olivier, Vasankari, T, Vestbo, J, Vezzani, G, Viegi, G, Visier, L, Vogelmeier, C, Vontetsianos, T, Wagstaff, R, Wahn, U, Wallaert, B, Whalley, B, Wickman, M, Williams, D M, Wilson, N, Yawn, B P, Yiallouros, P K, Yorgancioglu, A., Yusuf, O M, Zar, H J, Zhong, N, Zidarn, M, and Zuberbier, T

Published
2014

44. Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs.

Author

UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, J, Schünemann, H J, Samolinski, B, Demoly, P, Baena-Cagnani, C E, Bachert, C, Bonini, S, Boulet, L P, Bousquet, P J, Brozek, J L, Canonica, G W, Casale, T B, Cruz, A A, Fokkens, W J, Fonseca, J A, van Wijk, R Gerth, Grouse, L, Haahtela, T, Khaltaev, N, Kuna, P, Lockey, R F, Lodrup Carlsen, K C, Mullol, J, Naclerio, R, O'Hehir, R E, Ohta, K, Palkonen, S, Papadopoulos, N G, Passalacqua, G, Pawankar, R, Price, D, Ryan, D, Simons, F E R, Togias, A, Williams, D, Yorgancioglu, A., Yusuf, O M, Aberer, W, Adachi, M, Agache, I, Aït-Khaled, N, Akdis, C A, Andrianarisoa, A, Annesi-Maesano, I, Ansotegui, I J, Baiardini, I, Bateman, E D, Bedbrook, A, Beghé, B, Beji, M, Bel, E H, Ben Kheder, A, Bennoor, K S, Bergmann, K C, Berrissoul, F, Bieber, T, Bindslev Jensen, C, Blaiss, M S, Boner, A L, Bouchard, J, Braido, F, Brightling, C E, Bush, A, Caballero, F, Calderon, M A, Calvo, M A, Camargos, P A M, Caraballo, L R, Carlsen, K H, Carr, W, Cepeda, A M, Cesario, A, Chavannes, N H, Chen, Y Z, Chiriac, A M, Chivato Pérez, T, Chkhartishvili, E, Ciprandi, G, Costa, D J, Cox, L, Custovic, A, Dahl, R, Darsow, U, De Blay, F, Deleanu, D, Denburg, J A, Devillier, P, Didi, T, Dokic, D, Dolen, W K, Douagui, H, Dubakiene, R, Durham, S R, Dykewicz, M S, El-Gamal, Y, El-Meziane, A, Emuzyte, R, Fiocchi, A, Fletcher, M, Fukuda, T, Gamkrelidze, A, Gereda, J E, González Diaz, S, Gotua, M, Guzmán, M A, Hellings, P W, Hellquist-Dahl, B, Horak, F, Hourihane, J O'B, Howarth, P, Humbert, M, Ivancevich, J C, Jackson, C, Just, J, Kalayci, O, Kaliner, M A, Kalyoncu, A F, Keil, T, Keith, P K, Khayat, G, Kim, Y Y, Koffi N'goran, B, Koppelman, G H, Kowalski, M L, Kull, I, Kvedariene, V, Larenas-Linnemann, D, Le, L T, Lemière, C, Li, J, Lieberman, P, Lipworth, B, Mahboub, B, Makela, M J, Martin, F, Marshall, G D, Martinez, F D, Masjedi, M R, Maurer, M, Mavale-Manuel, S, Mazon, A, Melen, E, Meltzer, E O, Mendez, N H, Merk, H, Mihaltan, F, Mohammad, Y, Morais-Almeida, M, Muraro, A, Nafti, S, Namazova-Baranova, L, Nekam, K, Neou, A, Niggemann, B, Nizankowska-Mogilnicka, E, Nyembue, T D, Okamoto, Y, Okubo, K, Orru, M P, Ouedraogo, S, Ozdemir, C, Panzner, P, Pali-Schöll, I, Park, H S, Pigearias, B, Pohl, W, Popov, T A, Postma, D S, Potter, P, Rabe, K F, Ratomaharo, J, Reitamo, S, Ring, J, Roberts, R, Rogala, B, Romano, A, Roman Rodriguez, M, Rosado-Pinto, J, Rosenwasser, L, Rottem, M, Sanchez-Borges, M, Scadding, G K, Schmid-Grendelmeier, P, Sheikh, A, Sisul, J C, Solé, D, Sooronbaev, T, Spicak, V, Spranger, O, Stein, R T, Stoloff, S W, Sunyer, J, Szczeklik, A, Todo-Bom, A, Toskala, E, Tremblay, Y, Valenta, R, Valero, A L, Valeyre, D, Valiulis, A, Valovirta, E, Van Cauwenberge, P, Vandenplas, Olivier, van Weel, C, Vichyanond, P, Viegi, G, Wang, D Y, Wickman, M, Wöhrl, S, Wright, J, Yawn, B P, Yiallouros, P K, Zar, H J, Zernotti, M E, Zhong, N, Zidarn, M, Zuberbier, T, Burney, P G, Johnston, S L, Warner, J O, UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, J, Schünemann, H J, Samolinski, B, Demoly, P, Baena-Cagnani, C E, Bachert, C, Bonini, S, Boulet, L P, Bousquet, P J, Brozek, J L, Canonica, G W, Casale, T B, Cruz, A A, Fokkens, W J, Fonseca, J A, van Wijk, R Gerth, Grouse, L, Haahtela, T, Khaltaev, N, Kuna, P, Lockey, R F, Lodrup Carlsen, K C, Mullol, J, Naclerio, R, O'Hehir, R E, Ohta, K, Palkonen, S, Papadopoulos, N G, Passalacqua, G, Pawankar, R, Price, D, Ryan, D, Simons, F E R, Togias, A, Williams, D, Yorgancioglu, A., Yusuf, O M, Aberer, W, Adachi, M, Agache, I, Aït-Khaled, N, Akdis, C A, Andrianarisoa, A, Annesi-Maesano, I, Ansotegui, I J, Baiardini, I, Bateman, E D, Bedbrook, A, Beghé, B, Beji, M, Bel, E H, Ben Kheder, A, Bennoor, K S, Bergmann, K C, Berrissoul, F, Bieber, T, Bindslev Jensen, C, Blaiss, M S, Boner, A L, Bouchard, J, Braido, F, Brightling, C E, Bush, A, Caballero, F, Calderon, M A, Calvo, M A, Camargos, P A M, Caraballo, L R, Carlsen, K H, Carr, W, Cepeda, A M, Cesario, A, Chavannes, N H, Chen, Y Z, Chiriac, A M, Chivato Pérez, T, Chkhartishvili, E, Ciprandi, G, Costa, D J, Cox, L, Custovic, A, Dahl, R, Darsow, U, De Blay, F, Deleanu, D, Denburg, J A, Devillier, P, Didi, T, Dokic, D, Dolen, W K, Douagui, H, Dubakiene, R, Durham, S R, Dykewicz, M S, El-Gamal, Y, El-Meziane, A, Emuzyte, R, Fiocchi, A, Fletcher, M, Fukuda, T, Gamkrelidze, A, Gereda, J E, González Diaz, S, Gotua, M, Guzmán, M A, Hellings, P W, Hellquist-Dahl, B, Horak, F, Hourihane, J O'B, Howarth, P, Humbert, M, Ivancevich, J C, Jackson, C, Just, J, Kalayci, O, Kaliner, M A, Kalyoncu, A F, Keil, T, Keith, P K, Khayat, G, Kim, Y Y, Koffi N'goran, B, Koppelman, G H, Kowalski, M L, Kull, I, Kvedariene, V, Larenas-Linnemann, D, Le, L T, Lemière, C, Li, J, Lieberman, P, Lipworth, B, Mahboub, B, Makela, M J, Martin, F, Marshall, G D, Martinez, F D, Masjedi, M R, Maurer, M, Mavale-Manuel, S, Mazon, A, Melen, E, Meltzer, E O, Mendez, N H, Merk, H, Mihaltan, F, Mohammad, Y, Morais-Almeida, M, Muraro, A, Nafti, S, Namazova-Baranova, L, Nekam, K, Neou, A, Niggemann, B, Nizankowska-Mogilnicka, E, Nyembue, T D, Okamoto, Y, Okubo, K, Orru, M P, Ouedraogo, S, Ozdemir, C, Panzner, P, Pali-Schöll, I, Park, H S, Pigearias, B, Pohl, W, Popov, T A, Postma, D S, Potter, P, Rabe, K F, Ratomaharo, J, Reitamo, S, Ring, J, Roberts, R, Rogala, B, Romano, A, Roman Rodriguez, M, Rosado-Pinto, J, Rosenwasser, L, Rottem, M, Sanchez-Borges, M, Scadding, G K, Schmid-Grendelmeier, P, Sheikh, A, Sisul, J C, Solé, D, Sooronbaev, T, Spicak, V, Spranger, O, Stein, R T, Stoloff, S W, Sunyer, J, Szczeklik, A, Todo-Bom, A, Toskala, E, Tremblay, Y, Valenta, R, Valero, A L, Valeyre, D, Valiulis, A, Valovirta, E, Van Cauwenberge, P, Vandenplas, Olivier, van Weel, C, Vichyanond, P, Viegi, G, Wang, D Y, Wickman, M, Wöhrl, S, Wright, J, Yawn, B P, Yiallouros, P K, Zar, H J, Zernotti, M E, Zhong, N, Zidarn, M, Zuberbier, T, Burney, P G, Johnston, S L, and Warner, J O

Abstract

Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified AR as mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIA World Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children.

Published
2012

45. Systems medicine and integrated care to combat chronic noncommunicable diseases

Author

Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group) [research center], Bousquet, J., Anto, J. M., Sterk, P. J., Adcock, I. M., Chung, K. F., Roca, J., Agusti, A., Brightling, C., Cambon-Thomsen, A., Cesario, A., Abdelhak, S., Antonarakis, S. E., Avignon, A., Ballabio, A., Baraldi, E., Baranov, A., Bieber, T., Bockaert, J., Brahmachari, S., Brambilla, C., Bringer, J., Dauzat, M., Ernberg, I., Fabbri, L., Froguel, P., Galas, David J., Gojobori, T., Hunter, P., Jorgensen, C., Kauffmann, F., Kourilsky, P., Kowalski, M. L., Lancet, D., Pen, C. L., Mallet, J., Mayosi, B., Mercier, J., Metspalu, A., Nadeau, J. H., Ninot, G., Noble, D., Oztürk, M., Palkonen, S., Préfaut, C., Rabe, K., Renard, E., Roberts, R. G., Samolinski, B., Schünemann, H. J., Simon, H. U., Soares, M. B., Superti-Furga, G., Tegner, J., Verjovski-Almeida, S., Wellstead, P., Wolkenhauer, O., Wouters, E., Balling, Rudi, Brookes, A. J., Charron, D., Pison, C., Chen, Z., Hood, Leroy, Auffray, Charles, Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group) [research center], Bousquet, J., Anto, J. M., Sterk, P. J., Adcock, I. M., Chung, K. F., Roca, J., Agusti, A., Brightling, C., Cambon-Thomsen, A., Cesario, A., Abdelhak, S., Antonarakis, S. E., Avignon, A., Ballabio, A., Baraldi, E., Baranov, A., Bieber, T., Bockaert, J., Brahmachari, S., Brambilla, C., Bringer, J., Dauzat, M., Ernberg, I., Fabbri, L., Froguel, P., Galas, David J., Gojobori, T., Hunter, P., Jorgensen, C., Kauffmann, F., Kourilsky, P., Kowalski, M. L., Lancet, D., Pen, C. L., Mallet, J., Mayosi, B., Mercier, J., Metspalu, A., Nadeau, J. H., Ninot, G., Noble, D., Oztürk, M., Palkonen, S., Préfaut, C., Rabe, K., Renard, E., Roberts, R. G., Samolinski, B., Schünemann, H. J., Simon, H. U., Soares, M. B., Superti-Furga, G., Tegner, J., Verjovski-Almeida, S., Wellstead, P., Wolkenhauer, O., Wouters, E., Balling, Rudi, Brookes, A. J., Charron, D., Pison, C., Chen, Z., Hood, Leroy, and Auffray, Charles

Abstract

We propose an innovative, integrated, cost-effective health system to combat major non-communicable diseases (NCDs), including cardiovascular, chronic respiratory, metabolic, rheumatologic and neurologic disorders and cancers, which together are the predominant health problem of the 21st century. This proposed holistic strategy involves comprehensive patient-centered integrated care and multi-scale, multi-modal and multi-level systems approaches to tackle NCDs as a common group of diseases. Rather than studying each disease individually, it will take into account their intertwined gene-environment, socio-economic interactions and co-morbidities that lead to individual-specific complex phenotypes. It will implement a road map for predictive, preventive, personalized and participatory (P4) medicine based on a robust and extensive knowledge management infrastructure that contains individual patient information. It will be supported by strategic partnerships involving all stakeholders, including general practitioners associated with patient-centered care. This systems medicine strategy, which will take a holistic approach to disease, is designed to allow the results to be used globally, taking into account the needs and specificities of local economies and health systems.

Published
2011

46. Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper

Author

UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, Jean, Schünemann, H J, Zuberbier, T, Bachert, C, Baena-Cagnani, C E, Bousquet, P J, Brozek, J, Canonica, G W, Casale, T B, Demoly, P, Gerth van Wijk, R, Ohta, K, Bateman, E D, Calderon, M, Cruz, A A, Dolen, W K, Haughney, J, Lockey, R F, Lötvall, J, O'Byrne, P, Spranger, O, Togias, A, Bonini, S, Boulet, L P, Camargos, P, Carlsen, K H, Chavannes, N H, Delgado, L, Durham, S R, Fokkens, W J, Fonseca, J, Haahtela, T, Kalayci, O, Kowalski, M L, Larenas-Linnemann, D, Li, J, Mohammad, Y, Mullol, J, Naclerio, R, O'Hehir, R E, Papadopoulos, N, Passalacqua, G, Rabe, K F, Pawankar, R, Ryan, D, Samolinski, B, Simons, F E R, Valovirta, E, Yorgancioglu, A., Yusuf, O M, Agache, I, Aït-Khaled, N, Annesi-Maesano, I, Beghe, B, Ben Kheder, A, Blaiss, M S, Boakye, D A, Bouchard, J, Burney, P G, Busse, W W, Chan-Yeung, M, Chen, Y, Chuchalin, A G, Costa, D J, Custovic, A, Dahl, R, Denburg, J, Douagui, H, Emuzyte, R, Grouse, L, Humbert, M, Jackson, C, Johnston, S L, Kaliner, M A, Keith, P K, Kim, Y Y, Klossek, J M, Kuna, P, Le, L T, Lemiere, C, Lipworth, B, Mahboub, B, Malo, J L, Marshall, G D, Mavale-Manuel, S, Meltzer, E O, Morais-Almeida, M, Motala, C, Naspitz, C, Nekam, K, Niggemann, B, Nizankowska-Mogilnicka, E, Okamoto, Y, Orru, M P, Ouedraogo, S, Palkonen, S, Popov, T A, Price, D, Rosado-Pinto, J, Scadding, G K, Sooronbaev, T M, Stoloff, S W, Toskala, E, van Cauwenberge, P, Vandenplas, Olivier, van Weel, C, Viegi, G, Virchow, J C, Wang, D Y, Wickman, M, Williams, D, Yawn, B P, Zar, H J, Zernotti, M, Zhong, N, UCL - (MGD) Service de pneumologie, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, Bousquet, Jean, Schünemann, H J, Zuberbier, T, Bachert, C, Baena-Cagnani, C E, Bousquet, P J, Brozek, J, Canonica, G W, Casale, T B, Demoly, P, Gerth van Wijk, R, Ohta, K, Bateman, E D, Calderon, M, Cruz, A A, Dolen, W K, Haughney, J, Lockey, R F, Lötvall, J, O'Byrne, P, Spranger, O, Togias, A, Bonini, S, Boulet, L P, Camargos, P, Carlsen, K H, Chavannes, N H, Delgado, L, Durham, S R, Fokkens, W J, Fonseca, J, Haahtela, T, Kalayci, O, Kowalski, M L, Larenas-Linnemann, D, Li, J, Mohammad, Y, Mullol, J, Naclerio, R, O'Hehir, R E, Papadopoulos, N, Passalacqua, G, Rabe, K F, Pawankar, R, Ryan, D, Samolinski, B, Simons, F E R, Valovirta, E, Yorgancioglu, A., Yusuf, O M, Agache, I, Aït-Khaled, N, Annesi-Maesano, I, Beghe, B, Ben Kheder, A, Blaiss, M S, Boakye, D A, Bouchard, J, Burney, P G, Busse, W W, Chan-Yeung, M, Chen, Y, Chuchalin, A G, Costa, D J, Custovic, A, Dahl, R, Denburg, J, Douagui, H, Emuzyte, R, Grouse, L, Humbert, M, Jackson, C, Johnston, S L, Kaliner, M A, Keith, P K, Kim, Y Y, Klossek, J M, Kuna, P, Le, L T, Lemiere, C, Lipworth, B, Mahboub, B, Malo, J L, Marshall, G D, Mavale-Manuel, S, Meltzer, E O, Morais-Almeida, M, Motala, C, Naspitz, C, Nekam, K, Niggemann, B, Nizankowska-Mogilnicka, E, Okamoto, Y, Orru, M P, Ouedraogo, S, Palkonen, S, Popov, T A, Price, D, Rosado-Pinto, J, Scadding, G K, Sooronbaev, T M, Stoloff, S W, Toskala, E, van Cauwenberge, P, Vandenplas, Olivier, van Weel, C, Viegi, G, Virchow, J C, Wang, D Y, Wickman, M, Williams, D, Yawn, B P, Zar, H J, Zernotti, M, and Zhong, N

Abstract

The links between asthma and rhinitis are well characterized. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines stress the importance of these links and provide guidance for their prevention and treatment. Despite effective treatments being available, too few patients receive appropriate medical care for both diseases. Most patients with rhinitis and asthma consult primary care physicians and therefore these physicians are encouraged to understand and use ARIA guidelines. Patients should also be informed about these guidelines to raise their awareness of optimal care and increase control of the two related diseases. To apply these guidelines, clinicians and patients need to understand how and why the recommendations were made. The goal of the ARIA guidelines is to provide recommendations about the best management options for most patients in most situations. These recommendations should be based on the best available evidence. Making recommendations requires the assessment of the quality of available evidence, deciding on the balance between benefits and downsides, consideration of patients’ values and preferences, and, if applicable, resource implications. Guidelines must be updated as new management options become available or important new evidence emerges. Transparent reporting of guidelines facilitates understanding and acceptance, but implementation strategies need to be improved.

Published
2010

47. The CONSORT statement checklist in allergen-specific immunotherapy: a GA2LEN paper

Author

Bousquet, P J, Brozek, J, Bachert, C, Bieber, T, Bonini, S, Burney, P, Calderon, M, Canonica, G W, Compalati, E, Daures, J P, Delgado, L, Demoly, P, Dahl, R, Durham, S R, Kowalski, M L, Malling, H J, Merk, H, Papadopoulos, N, Passalacqua, G, Simon, H U, Worms, M, Wahn, U, Zuberbier, T, Schünemann, H J, Bousquet, J, Bousquet, P J, Brozek, J, Bachert, C, Bieber, T, Bonini, S, Burney, P, Calderon, M, Canonica, G W, Compalati, E, Daures, J P, Delgado, L, Demoly, P, Dahl, R, Durham, S R, Kowalski, M L, Malling, H J, Merk, H, Papadopoulos, N, Passalacqua, G, Simon, H U, Worms, M, Wahn, U, Zuberbier, T, Schünemann, H J, and Bousquet, J

Abstract

Udgivelsesdato: 2009-Dec, The methodology of randomized clinical trials is essential for the critical assessment and registration of therapeutic interventions. The CONSORT (Consolidated Standards of Reporting Trials) statement was developed to alleviate the problems arising from the inadequate reporting of randomized controlled trials. The present article reflects on the items that we believe should be included in the CONSORT checklist in the context of conducting and reporting trials in allergen-specific immunotherapy. Only randomized, blinded (in particular blinding of patients, health care providers, and outcome assessors), placebo-controlled Phase III studies in this article. Our analysis focuses on the definition of patients' inclusion and exclusion criteria, allergen standardization, primary, secondary and exploratory outcomes, reporting of adverse events and analysis.

Published
2009

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