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6 results on '"Schouwink G"'

1. Narcolepsy

Author

Lammers, G. J., van Dijk, J. G., Kamphuisen, H. A.C., Arends, J., Declerck, A. C., Schouwink, G., and Troost, J.

Published
1991

2. Ritanserin, a 5-HT2 receptor blocker, as add-on treatment in narcolepsy

Author

Gert Jan Lammers, Arends J, Ac, Declerck, Ha, Kamphuisen, Schouwink G, and Troost J

Subjects
Adult, Placebos, Adolescent, Double-Blind Method, Histamine H2 Antagonists, Piperidines, Ritanserin, Animals, Humans, Middle Aged, Sleep, Circadian Rhythm, Narcolepsy
Abstract

In a double-blind placebo-controlled trial, ritanserin (a 5-HT2 receptor blocker) 5 mg/day or placebo was added to the usual medication in 28 patients with narcolepsy during 4 wk. The effect was assessed by means of polysomnography, daily and weekly subjective evaluations, and Multiple sleep latency tests (MSLT). During the night ritanserin increased the amount of nonrapid eye movement slow wave sleep and reduced wakefulness after sleep onset. It improved the feeling of being refreshed in the morning after awakening and reduced subjective daytime sleepiness. The drug did not significantly influence sleep latency in the MSLT.

Published
1991

4. Ritanserin, a 5-HT2 receptor blocker, as add-on treatment in narcolepsy.

Author

Lammers GJ, Arends J, Declerck AC, Kamphuisen HA, Schouwink G, and Troost J

Subjects
Adolescent, Adult, Animals, Circadian Rhythm drug effects, Double-Blind Method, Humans, Middle Aged, Placebos, Ritanserin, Sleep drug effects, Histamine H2 Antagonists therapeutic use, Narcolepsy drug therapy, Piperidines therapeutic use
Abstract

In a double-blind placebo-controlled trial, ritanserin (a 5-HT2 receptor blocker) 5 mg/day or placebo was added to the usual medication in 28 patients with narcolepsy during 4 wk. The effect was assessed by means of polysomnography, daily and weekly subjective evaluations, and Multiple sleep latency tests (MSLT). During the night ritanserin increased the amount of nonrapid eye movement slow wave sleep and reduced wakefulness after sleep onset. It improved the feeling of being refreshed in the morning after awakening and reduced subjective daytime sleepiness. The drug did not significantly influence sleep latency in the MSLT.

Published
1991

5. [Neuromuscular diseases in adolescence].

Author

Schouwink G

Subjects
Adolescent, Female, Humans, Life Style, Male, Neuromuscular Diseases diagnosis, Neuromuscular Diseases psychology, Neuromuscular Diseases rehabilitation
Published
1978

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