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1. A Dutch paediatric palliative care guideline: a systematic review and evidence-based recommendations for symptom treatment

Author

Infection & Immunity, Kinderbewegingszorg patientenzorg, Zorg en O&O, KinderComfortTeam, van Teunenbroek, Kim C., Mulder, Renée L., Ahout, Inge M.L., Bindels-de Heus, Karen G.C.B., Delsman-van Gelder, Catharina M., Galimont-Collen, Annemie F.S., de Groot, Marinka A.R., Heitink-Polle, Katja M.J., Looijestijn, Jeffry, Mensink, Maarten O., Mulder, Selma, Schieving, Jolanda H., Schouten-van Meeteren, Antoinette Y.N., Verheijden, Johannes M.A., Rippen, Hester, Borggreve, Brigitt C.M., Kremer, Leontien C.M., Verhagen, A. A.Eduard, Michiels, Erna M.C., Infection & Immunity, Kinderbewegingszorg patientenzorg, Zorg en O&O, KinderComfortTeam, van Teunenbroek, Kim C., Mulder, Renée L., Ahout, Inge M.L., Bindels-de Heus, Karen G.C.B., Delsman-van Gelder, Catharina M., Galimont-Collen, Annemie F.S., de Groot, Marinka A.R., Heitink-Polle, Katja M.J., Looijestijn, Jeffry, Mensink, Maarten O., Mulder, Selma, Schieving, Jolanda H., Schouten-van Meeteren, Antoinette Y.N., Verheijden, Johannes M.A., Rippen, Hester, Borggreve, Brigitt C.M., Kremer, Leontien C.M., Verhagen, A. A.Eduard, and Michiels, Erna M.C.

Published
2024

2. The development of fatigue after treatment for pediatric brain tumors does not differ between tumor locations

Author

P&O Programma's, Flex en UMCU-breed, Endocrinologie patientenzorg, Brain, Cancer, Child Health, Highfield Research Group, Speerpunt, Zorg en O&O, Irestorm, Elin, Schouten-van Meeteren, Antoinette Y.N., van Gorp, Marloes, Twisk, Jos W.R., van Santen, Hanneke M., Partanen, Marita, Grootenhuis, Martha A., van Litsenburg, Raphaele R.L., P&O Programma's, Flex en UMCU-breed, Endocrinologie patientenzorg, Brain, Cancer, Child Health, Highfield Research Group, Speerpunt, Zorg en O&O, Irestorm, Elin, Schouten-van Meeteren, Antoinette Y.N., van Gorp, Marloes, Twisk, Jos W.R., van Santen, Hanneke M., Partanen, Marita, Grootenhuis, Martha A., and van Litsenburg, Raphaele R.L.

Published
2024

3. A Dutch paediatric palliative care guideline:a systematic review and evidence-based recommendations for symptom treatment

Author

van Teunenbroek, Kim C., Mulder, Renée L., Ahout, Inge M.L., Bindels-de Heus, Karen G.C.B., Delsman-van Gelder, Catharina M., Galimont-Collen, Annemie F.S., de Groot, Marinka A.R., Heitink-Polle, Katja M.J., Looijestijn, Jeffry, Mensink, Maarten O., Mulder, Selma, Schieving, Jolanda H., Schouten-van Meeteren, Antoinette Y.N., Verheijden, Johannes M.A., Rippen, Hester, Borggreve, Brigitt C.M., Kremer, Leontien C.M., Verhagen, A. A.Eduard, Michiels, Erna M.C., van Teunenbroek, Kim C., Mulder, Renée L., Ahout, Inge M.L., Bindels-de Heus, Karen G.C.B., Delsman-van Gelder, Catharina M., Galimont-Collen, Annemie F.S., de Groot, Marinka A.R., Heitink-Polle, Katja M.J., Looijestijn, Jeffry, Mensink, Maarten O., Mulder, Selma, Schieving, Jolanda H., Schouten-van Meeteren, Antoinette Y.N., Verheijden, Johannes M.A., Rippen, Hester, Borggreve, Brigitt C.M., Kremer, Leontien C.M., Verhagen, A. A.Eduard, and Michiels, Erna M.C.

Abstract

Background: Children with life-threatening and life-limiting conditions can experience high levels of suffering due to multiple distressing symptoms that result in poor quality of life and increase risk of long-term distress in their family members. High quality symptom treatment is needed for all these children and their families, even more so at the end-of-life. In this paper, we provide evidence-based recommendations for symptom treatment in paediatric palliative patients to optimize care. Methods: A multidisciplinary panel of 56 experts in paediatric palliative care and nine (bereaved) parents was established to develop recommendations on symptom treatment in paediatric palliative care including anxiety and depression, delirium, dyspnoea, haematological symptoms, coughing, skin complaints, nausea and vomiting, neurological symptoms, pain, death rattle, fatigue, paediatric palliative sedation and forgoing hydration and nutrition. Recommendations were based on evidence from a systematic literature search, additional literature sources (such as guidelines), clinical expertise, and patient and family values. We used the GRADE methodology for appraisal of evidence. Parents were included in the guideline panel to ensure the representation of patient and family values. Results: We included a total of 18 studies that reported on the effects of specific (non) pharmacological interventions to treat symptoms in paediatric palliative care. A few of these interventions showed significant improvement in symptom relief. This evidence could only (partly) answer eight out of 27 clinical questions. We included 29 guidelines and two textbooks as additional literature to deal with lack of evidence. In total, we formulated 221 recommendations on symptom treatment in paediatric palliative care based on evidence, additional literature, clinical expertise, and patient and family values. Conclusion: Even though available evidence on symptom-related paediatric palliative care interven

Published
2024

4. Diagnostic accuracy of retinal optical coherence tomography in children with a newly diagnosed brain tumour

Author

Oogheelkunde Onderzoek, Cancer, Zorgeenheid Oogheelkunde Medisch, MS KNO, Brain, MS Oogheelkunde, Arts-Assistenten Onderwijs Radiologie, Infection & Immunity, Nuijts, Myrthe A., Stegeman, Inge, Porro, Giorgio L., Bennebroek, Carlien A.M., van Seeters, Tom, Proudlock, Frank A., Schouten – van Meeteren, Antoinette Y.N., Imhof, Saskia M., Oogheelkunde Onderzoek, Cancer, Zorgeenheid Oogheelkunde Medisch, MS KNO, Brain, MS Oogheelkunde, Arts-Assistenten Onderwijs Radiologie, Infection & Immunity, Nuijts, Myrthe A., Stegeman, Inge, Porro, Giorgio L., Bennebroek, Carlien A.M., van Seeters, Tom, Proudlock, Frank A., Schouten – van Meeteren, Antoinette Y.N., and Imhof, Saskia M.

Published
2023

6. Safety of Growth Hormone Replacement Therapy in Childhood-Onset Craniopharyngioma: A Systematic Review and Cohort Study

Author

van Schaik, Jiska, primary, Kormelink, Eline, additional, Kabak, Eda, additional, van Dalen, Elvira C, additional, Schouten-van Meeteren, Antoinette Y.N., additional, de Vos-Kerkhof, Evelien, additional, Bakker, Boudewijn, additional, Fiocco, Marta, additional, Hoving, Eelco W., additional, Tissing, Wim J.E., additional, and van Santen, Hanneke M., additional

Published
2023
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7. Impact of Bevacizumab on Visual Function, Tumor Size, and Toxicity in Pediatric Progressive Optic Pathway Glioma: A Retrospective Nationwide Multicentre Study

Author

Bennebroek, Carlien A.M., Zwol, Judith van, Porro, Giorgio L.L., Oostenbrink, Rianne, Dittrich, A.T.M., Groot, A.L.W., Graaf, Pim de, Schouten-van Meeteren, Antoinette Y.N., Bennebroek, Carlien A.M., Zwol, Judith van, Porro, Giorgio L.L., Oostenbrink, Rianne, Dittrich, A.T.M., Groot, A.L.W., Graaf, Pim de, and Schouten-van Meeteren, Antoinette Y.N.

Abstract

Item does not contain fulltext

Published
2022

8. Impact of Bevacizumab on Visual Function, Tumor Size, and Toxicity in Pediatric Progressive Optic Pathway Glioma:A Retrospective Nationwide Multicentre Study

Author

Bennebroek, Carlien A.M., van Zwol, Judith, Porro, Giorgio L., Oostenbrink, Rianne, Dittrich, Anne T.M., Groot, Annabel L.W., Pott, Jan W., Janssen, Etienne J.M., Bauer, Noël J., van Genderen, Maria M., Saeed, Peerooz, Lequin, Maarten H., de Graaf, Pim, Schouten-van Meeteren, Antoinette Y.N., Bennebroek, Carlien A.M., van Zwol, Judith, Porro, Giorgio L., Oostenbrink, Rianne, Dittrich, Anne T.M., Groot, Annabel L.W., Pott, Jan W., Janssen, Etienne J.M., Bauer, Noël J., van Genderen, Maria M., Saeed, Peerooz, Lequin, Maarten H., de Graaf, Pim, and Schouten-van Meeteren, Antoinette Y.N.

Abstract

Backgrounds: Bevacizumab (BVZ) is used as a subsequent line of treatment for pediatric optic pathway glioma (OPG) in the case of progression. Data on the treatment effect concerning tumor progression and visual function are scarce and nationwide studies are lacking. Methods: We performed a retrospective, nationwide, multicentre cohort study including all pediatric patients with OPG treated with BVZ in the Netherlands (2009–2021). Progression-free survival, change in visual acuity and visual field, MRI-based radiologic response, and toxicity were evaluated. Results: In total, 33 pediatric patients with OPG were treated with BVZ (median 12 months). Visual acuity improved in 20.5%, remained stable in 74.4%, and decreased in 5.1% of 39 of all analysed eyes. The monocular visual field improved in 73.1%, remained stable in 15.4%, and decreased in 7.7% of 25 analysed eyes. Radiologic response at the end of therapy showed a partial response in 7 patients (21.9%), minor response in 7 (21.9%), stable disease in 15 (46.9%), and progressive disease in 3 (9.3%). Progression-free survival at 18 and 36 months after the start of BVZ reduced from 70.9% to 38.0%. Toxicity (≥grade 3 CTCAE) during treatment was observed in five patients (15.2%). Conclusion: Treatment of BVZ in pediatric patients with OPG revealed stabilisation in the majority of patients, but was followed by progression at a later time point in more than 60% of patients. This profile seems relatively acceptable given the benefits of visual field improvement in more than 70% of analysed eyes and visual acuity improvement in more than 20% of eyes at the cessation of BVZ.

Published
2022

9. Dextroamphetamine Treatment in Children With Hypothalamic Obesity

Author

Endocrinologie onderzoek, Activity&Health sectie exercise, Endocrinologie patientenzorg, PMC Medisch specialisten, Brain, Child Health, Cancer, van Schaik, Jiska, Welling, Mila S., de Groot, Corjan J., van Eck, Judith P., Juriaans, Alicia, Burghard, Marcella, Oude Ophuis, Sebastianus B.J., Bakker, Boudewijn, Tissing, Wim J.E., Schouten-van Meeteren, Antoinette Y.N., van den Akker, Erica L.T., van Santen, Hanneke M., Endocrinologie onderzoek, Activity&Health sectie exercise, Endocrinologie patientenzorg, PMC Medisch specialisten, Brain, Child Health, Cancer, van Schaik, Jiska, Welling, Mila S., de Groot, Corjan J., van Eck, Judith P., Juriaans, Alicia, Burghard, Marcella, Oude Ophuis, Sebastianus B.J., Bakker, Boudewijn, Tissing, Wim J.E., Schouten-van Meeteren, Antoinette Y.N., van den Akker, Erica L.T., and van Santen, Hanneke M.

Published
2022

10. Transition From Diencephalic Syndrome to Hypothalamic Obesity in Children With Suprasellar Low Grade Glioma: A Case Series

Author

Endocrinologie onderzoek, Cancer, Neurochirurgen, Endocrinologie patientenzorg, Brain, Child Health, van Roessel, Ichelle M.A.A., Schouten-van Meeteren, Antoinette Y.N., Meijer, Lisethe, Hoving, Eelco W., Bakker, Boudewijn, van Santen, Hanneke M., Endocrinologie onderzoek, Cancer, Neurochirurgen, Endocrinologie patientenzorg, Brain, Child Health, van Roessel, Ichelle M.A.A., Schouten-van Meeteren, Antoinette Y.N., Meijer, Lisethe, Hoving, Eelco W., Bakker, Boudewijn, and van Santen, Hanneke M.

Published
2022

11. Hypothalamic-Pituitary and Other Endocrine Surveillance Among Childhood Cancer Survivors

Author

Endocrinologie onderzoek, Child Health, Cancer, Neurochirurgen, MS Interne Geneeskunde, MS Radiotherapie, Endocrinologie patientenzorg, Brain, van Iersel, Laura, Mulder, Renee L., Denzer, Christian, Cohen, Laurie E., Spoudeas, Helen A., Meacham, Lillian R., Sugden, Elaine, Schouten-van Meeteren, Antoinette Y.N., Hoving, Eelco W., Packer, Roger J., Armstrong, Gregory T., Mostoufi-Moab, Sogol, Stades, Aline M., van Vuurden, Dannis, Janssens, Geert O., Thomas-Teinturier, Cécile, Murray, Robert D., Di Iorgi, Natascia, Neggers, Sebastian J.C.M.M., Thompson, Joel, Toogood, Andrew A., Gleeson, Helena, Follin, Cecilia, Bardi, Edit, Torno, Lilibeth, Patterson, Briana, Morsellino, Vera, Sommer, Grit, Clement, Sarah C., Srivastava, Deokumar, Kiserud, Cecilie E., Fernandez, Alberto, Scheinemann, Katrin, Raman, Sripriya, Yuen, Kevin C.J., Wallace, W. Hamish, Constine, Louis S., Skinner, Roderick, Hudson, Melissa M., Kremer, Leontien C.M., Chemaitilly, Wassim, van Santen, Hanneke M., Endocrinologie onderzoek, Child Health, Cancer, Neurochirurgen, MS Interne Geneeskunde, MS Radiotherapie, Endocrinologie patientenzorg, Brain, van Iersel, Laura, Mulder, Renee L., Denzer, Christian, Cohen, Laurie E., Spoudeas, Helen A., Meacham, Lillian R., Sugden, Elaine, Schouten-van Meeteren, Antoinette Y.N., Hoving, Eelco W., Packer, Roger J., Armstrong, Gregory T., Mostoufi-Moab, Sogol, Stades, Aline M., van Vuurden, Dannis, Janssens, Geert O., Thomas-Teinturier, Cécile, Murray, Robert D., Di Iorgi, Natascia, Neggers, Sebastian J.C.M.M., Thompson, Joel, Toogood, Andrew A., Gleeson, Helena, Follin, Cecilia, Bardi, Edit, Torno, Lilibeth, Patterson, Briana, Morsellino, Vera, Sommer, Grit, Clement, Sarah C., Srivastava, Deokumar, Kiserud, Cecilie E., Fernandez, Alberto, Scheinemann, Katrin, Raman, Sripriya, Yuen, Kevin C.J., Wallace, W. Hamish, Constine, Louis S., Skinner, Roderick, Hudson, Melissa M., Kremer, Leontien C.M., Chemaitilly, Wassim, and van Santen, Hanneke M.

Published
2022

12. Ophthalmological Evaluation in Children Presenting with a Primary Brain Tumor

Author

Oogheelkunde Onderzoek, Cancer, Zorglijn Achtersegment, MS KNO, Brain, MS Oogheelkunde, Neurochirurgen, Infection & Immunity, Nuijts, Myrthe A., Stegeman, Inge, Porro, Giorgio L., Duvekot, Josje C., Van Egmond-Ebbeling, Michelle B., Van Der Linden, Denise C.P., Hoving, Eelco W., Schouten-Van Meeteren, Antoinette Y.N., Imhof, Saskia M., Oogheelkunde Onderzoek, Cancer, Zorglijn Achtersegment, MS KNO, Brain, MS Oogheelkunde, Neurochirurgen, Infection & Immunity, Nuijts, Myrthe A., Stegeman, Inge, Porro, Giorgio L., Duvekot, Josje C., Van Egmond-Ebbeling, Michelle B., Van Der Linden, Denise C.P., Hoving, Eelco W., Schouten-Van Meeteren, Antoinette Y.N., and Imhof, Saskia M.

Published
2022

13. Ophthalmological Findings in Youths with a Newly Diagnosed Brain Tumor

Author

Nuijts, Myrthe A., Stegeman, Inge, Van Seeters, Tom, Borst, Marloes D., Bennebroek, Carlien A.M., Buis, Dennis R., Naus, Nicole C., Porro, Giorgio L., Van Egmond-Ebbeling, Michelle B., Voskuil-Kerkhof, Elisabeth S.M., Pott, Janwillem R., Franke, Niels E., De Vos-Kerkhof, Evelien, Hoving, Eelco W., Schouten-Van Meeteren, Antoinette Y.N., Imhof, Saskia M., Ophthalmology, Epidemiology and Data Science, Graduate School, Neurosurgery, Paediatric Oncology, and Paediatrics

Subjects
Male, Ophthalmology, Adolescent, Brain Neoplasms, Vision Tests, Vision Disorders, Humans, Vision, Low, Female, Prospective Studies, Visual Fields, Child
Abstract

ImportanceVisual impairment is an irreversible adverse effect in individuals who experienced a childhood brain tumor. Ophthalmological evaluation at diagnosis enables early detection of vision loss, decision-making about treatment, and when applicable, the timely use of visual interventions. However, awareness of visual impairment in clinical practice is suboptimal, and adherence to ophthalmological evaluation needs to be improved.ObjectiveTo assess the prevalence and types of abnormal ophthalmological findings in youths with a newly diagnosed brain tumor.Design, Setting, and ParticipantsIn this nationwide, prospective cohort study, youths aged 0 to 18 years with a newly diagnosed brain tumor between May 15, 2019, and August 11, 2021, were consecutively enrolled in 4 hospitals in the Netherlands, including the dedicated tertiary referral center for pediatric oncology care.ExposuresA standardized and comprehensive ophthalmological examination, including orthoptic evaluation, visual acuity testing, visual field examination, and ophthalmoscopy, was performed within 4 weeks from brain tumor diagnosis.Main Outcomes and MeasuresThe main outcomes were prevalence and types of visual symptoms and abnormal ophthalmological findings at brain tumor diagnosis.ResultsOf 170 youths included in the study (96 [56.5%] male; median age, 8.3 years [range, 0.2-17.8 years]), 82 (48.2%) had infratentorial tumors; 53 (31.2%), supratentorial midline tumors; and 35 (20.6%), cerebral hemisphere tumors. A total of 161 patients (94.7%) underwent orthoptic evaluation (67 [41.6%] preoperatively; 94 [58.4%] postoperatively); 152 (89.4%), visual acuity testing (63 [41.4%] preoperatively; 89 [58.6%] postoperatively); 121 (71.2%), visual field examination (49 [40.4%] preoperatively; 72 [59.6%] postoperatively); and 164 (96.5%), ophthalmoscopy (82 [50.0%] preoperatively; 82 [50.0%] postoperatively). Overall, 101 youths (59.4%) presented with visual symptoms at diagnosis. Abnormal findings were found in 134 patients (78.8%) during ophthalmological examination. The most common abnormal findings were papilledema in 86 of 164 patients (52.4%) who underwent ophthalmoscopy, gaze deficits in 54 of 161 (33.5%) who underwent orthoptic evaluation, visual field defects in 32 of 114 (28.1%) with reliable visual field examination, nystagmus in 40 (24.8%) and strabismus in 32 (19.9%) of 161 who underwent orthoptic evaluation, and decreased visual acuity in 13 of 152 (8.6%) with reliable visual acuity testing. Forty-five of 69 youths (65.2%) without visual symptoms at diagnosis had ophthalmological abnormalities on examination.Conclusions and RelevanceThe results of this study suggest that there is a high prevalence of abnormal ophthalmological findings in youths at brain tumor diagnosis regardless of the presence of visual symptoms. These findings support the need of standardized ophthalmological examination and the awareness of ophthalmologists and referring oncologists, neurologists, and neurosurgeons for ophthalmological abnormalities in this patient group.

Published
2022

15. The diagnostic accuracy and prognostic value of OCT for the evaluation of the visual function in children with a brain tumour: A systematic review

Author

Oogheelkunde Onderzoek, Cancer, MS Oogheelkunde, Infection & Immunity, MS Dermatologie/Allergologie, Zorglijn Achtersegment, MS KNO, Brain, Nuijts, Myrthe A., Imhof, Saskia M., Veldhuis, Nienke, Dekkers, Coco C., Schouten-Van Meeteren, Antoinette Y.N., Stegeman, Inge, Oogheelkunde Onderzoek, Cancer, MS Oogheelkunde, Infection & Immunity, MS Dermatologie/Allergologie, Zorglijn Achtersegment, MS KNO, Brain, Nuijts, Myrthe A., Imhof, Saskia M., Veldhuis, Nienke, Dekkers, Coco C., Schouten-Van Meeteren, Antoinette Y.N., and Stegeman, Inge

Published
2021

20. The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas

Author

ZL Kinder Ner en Nec Medisch, Brain, Pathologie mortuarium en obductie, Pathologie Pathologen staf, Cancer, Pathologie Opleiding, Pathologie, Bongaarts, Anika, van Scheppingen, Jackelien, Korotkov, Anatoly, Mijnsbergen, Caroline, Anink, Jasper J., Jansen, Floor E., Spliet, Wim G.M., den Dunnen, Wilfred F.A., Gruber, Victoria E., Scholl, Theresa, Samueli, Sharon, Hainfellner, Johannes A., Feucht, Martha, Kotulska, Katarzyna, Jozwiak, Sergiusz, Grajkowska, Wieslawa, Buccoliero, Anna Maria, Caporalini, Chiara, Giordano, Flavio, Genitori, Lorenzo, Coras, Roland, Blümcke, Ingmar, Krsek, Pavel, Zamecnik, Josef, Meijer, Lisethe, Scicluna, Brendon P., Schouten-van Meeteren, Antoinette Y.N., Mühlebner, Angelika, Mills, James D., Aronica, Eleonora, ZL Kinder Ner en Nec Medisch, Brain, Pathologie mortuarium en obductie, Pathologie Pathologen staf, Cancer, Pathologie Opleiding, Pathologie, Bongaarts, Anika, van Scheppingen, Jackelien, Korotkov, Anatoly, Mijnsbergen, Caroline, Anink, Jasper J., Jansen, Floor E., Spliet, Wim G.M., den Dunnen, Wilfred F.A., Gruber, Victoria E., Scholl, Theresa, Samueli, Sharon, Hainfellner, Johannes A., Feucht, Martha, Kotulska, Katarzyna, Jozwiak, Sergiusz, Grajkowska, Wieslawa, Buccoliero, Anna Maria, Caporalini, Chiara, Giordano, Flavio, Genitori, Lorenzo, Coras, Roland, Blümcke, Ingmar, Krsek, Pavel, Zamecnik, Josef, Meijer, Lisethe, Scicluna, Brendon P., Schouten-van Meeteren, Antoinette Y.N., Mühlebner, Angelika, Mills, James D., and Aronica, Eleonora

Published
2020

21. Histopathologic features of retinoblastoma and its relation with in vitro drug resistance measured by means of the MTT assay

Author

Schouten-van Meeteren, antoinette Y.N., der Valk, Paul van, der Linden, Hans C.van, Moll, Annette C., Imhof, Saskia M., Huismans, Dieuwke R., Loonen, Anne H., and Veerman, Anjo J.P.

Subjects
Retinoblastoma -- Drug therapy, Drug resistance -- Physiological aspects, Calcification -- Physiological aspects, Histology, Pathological -- Analysis, Health
Published
2001

24. MicroRNA519d and microRNA4758 can identify gangliogliomas from dysembryoplastic neuroepithelial tumours and astrocytomas

Author

Bongaarts, Anika, primary, Prabowo, Avanita S., additional, Arena, Andrea, additional, Anink, Jasper J., additional, Reinten, Roy J., additional, Jansen, Floor E., additional, Spliet, Wim G.M., additional, Thom, Maria, additional, Coras, Roland, additional, Blümcke, Ingmar, additional, Kotulska, Katarzyna, additional, Jozwiak, Sergiusz, additional, Grajkowska, Wieslawa, additional, Söylemezoğlu, Figen, additional, Pimentel, José, additional, Schouten-van Meeteren, Antoinette Y.N., additional, Mills, James D., additional, Iyer, Anand M., additional, van Vliet, Erwin A., additional, Mühlebner, Angelika, additional, and Aronica, Eleonora, additional

Published
2018
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26. Biological material collection to advance translational research and treatment of children with CNS tumours : position paper from the SIOPE Brain Tumour Group

Author

Rutkowski, Stefan, Modena, Piergiorgio, Williamson, Daniel, Kerl, Kornelius, Nysom, Karsten, Pizer, Barry, Bartels, Ute, Puget, Stephanie, Doz, François, Michalski, Antony, von Hoff, Katja, Chevignard, Mathilde, Avula, Shivaram, Murray, Matthew J., Schönberger, Stefan, Czech, Thomas, Schouten-van Meeteren, Antoinette Y.N., Kordes, Uwe, Kramm, Christof M., van Vuurden, Dannis G., Hulleman, Esther, Janssens, Geert O., Solanki, Guirish A., van Veelen, Marie Luise C., Thomale, Ulrich, Schuhmann, Martin U., Jones, Chris, Giangaspero, Felice, Figarella-Branger, Dominique, Pietsch, Torsten, Clifford, Steve C., Pfister, Stefan M., Van Gool, Stefaan W., Rutkowski, Stefan, Modena, Piergiorgio, Williamson, Daniel, Kerl, Kornelius, Nysom, Karsten, Pizer, Barry, Bartels, Ute, Puget, Stephanie, Doz, François, Michalski, Antony, von Hoff, Katja, Chevignard, Mathilde, Avula, Shivaram, Murray, Matthew J., Schönberger, Stefan, Czech, Thomas, Schouten-van Meeteren, Antoinette Y.N., Kordes, Uwe, Kramm, Christof M., van Vuurden, Dannis G., Hulleman, Esther, Janssens, Geert O., Solanki, Guirish A., van Veelen, Marie Luise C., Thomale, Ulrich, Schuhmann, Martin U., Jones, Chris, Giangaspero, Felice, Figarella-Branger, Dominique, Pietsch, Torsten, Clifford, Steve C., Pfister, Stefan M., and Van Gool, Stefaan W.

Published
2018

27. The development of hypothalamic obesity in craniopharyngioma patients : A risk factor analysis in a well-defined cohort

Author

van Iersel, Laura, Meijneke, Ruud W.H., Schouten-van Meeteren, Antoinette Y.N., Reneman, Liesbeth, de Win, Maartje M., van Trotsenburg, A. S.Paul, Bisschop, Peter H., Finken, Martijn J.J., Vandertop, W. Peter, van Furth, Wouter R., van Santen, Hanneke M., van Iersel, Laura, Meijneke, Ruud W.H., Schouten-van Meeteren, Antoinette Y.N., Reneman, Liesbeth, de Win, Maartje M., van Trotsenburg, A. S.Paul, Bisschop, Peter H., Finken, Martijn J.J., Vandertop, W. Peter, van Furth, Wouter R., and van Santen, Hanneke M.

Published
2018

28. Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group

Author

UMC Utrecht, MS Radiotherapie, Cancer, Rutkowski, Stefan, Modena, Piergiorgio, Williamson, Daniel, Kerl, Kornelius, Nysom, Karsten, Pizer, Barry, Bartels, Ute, Puget, Stephanie, Doz, François, Michalski, Antony, von Hoff, Katja, Chevignard, Mathilde, Avula, Shivaram, Murray, Matthew J., Schönberger, Stefan, Czech, Thomas, Schouten-van Meeteren, Antoinette Y.N., Kordes, Uwe, Kramm, Christof M., van Vuurden, Dannis G., Hulleman, Esther, Janssens, Geert O., Solanki, Guirish A., van Veelen, Marie Luise C., Thomale, Ulrich, Schuhmann, Martin U., Jones, Chris, Giangaspero, Felice, Figarella-Branger, Dominique, Pietsch, Torsten, Clifford, Steve C., Pfister, Stefan M., Van Gool, Stefaan W., UMC Utrecht, MS Radiotherapie, Cancer, Rutkowski, Stefan, Modena, Piergiorgio, Williamson, Daniel, Kerl, Kornelius, Nysom, Karsten, Pizer, Barry, Bartels, Ute, Puget, Stephanie, Doz, François, Michalski, Antony, von Hoff, Katja, Chevignard, Mathilde, Avula, Shivaram, Murray, Matthew J., Schönberger, Stefan, Czech, Thomas, Schouten-van Meeteren, Antoinette Y.N., Kordes, Uwe, Kramm, Christof M., van Vuurden, Dannis G., Hulleman, Esther, Janssens, Geert O., Solanki, Guirish A., van Veelen, Marie Luise C., Thomale, Ulrich, Schuhmann, Martin U., Jones, Chris, Giangaspero, Felice, Figarella-Branger, Dominique, Pietsch, Torsten, Clifford, Steve C., Pfister, Stefan M., and Van Gool, Stefaan W.

Published
2018

29. The development of hypothalamic obesity in craniopharyngioma patients: A risk factor analysis in a well-defined cohort

Author

Endocrinologie patientenzorg, Child Health, Arts-assistenten Kinderen, van Iersel, Laura, Meijneke, Ruud W.H., Schouten-van Meeteren, Antoinette Y.N., Reneman, Liesbeth, de Win, Maartje M., van Trotsenburg, A. S.Paul, Bisschop, Peter H., Finken, Martijn J.J., Vandertop, W. Peter, van Furth, Wouter R., van Santen, Hanneke M., Endocrinologie patientenzorg, Child Health, Arts-assistenten Kinderen, van Iersel, Laura, Meijneke, Ruud W.H., Schouten-van Meeteren, Antoinette Y.N., Reneman, Liesbeth, de Win, Maartje M., van Trotsenburg, A. S.Paul, Bisschop, Peter H., Finken, Martijn J.J., Vandertop, W. Peter, van Furth, Wouter R., and van Santen, Hanneke M.

Published
2018

30. The development of hypothalamic obesity in craniopharyngioma patients: A risk factor analysis in a well-defined cohort

Author

van Iersel, Laura, primary, Meijneke, Ruud W.H., additional, Schouten-van Meeteren, Antoinette Y.N., additional, Reneman, Liesbeth, additional, de Win, Maartje M., additional, van Trotsenburg, A.S. Paul, additional, Bisschop, Peter H., additional, Finken, Martijn J.J., additional, Vandertop, W. Peter, additional, van Furth, Wouter R., additional, and van Santen, Hanneke M., additional

Published
2018
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31. Subependymal giant cell astrocytomas in Tuberous Sclerosis Complex have consistent TSC1/TSC2 biallelic inactivation, and no BRAF mutations

Author

Bongaarts, Anika, primary, Giannikou, Krinio, additional, Reinten, Roy J., additional, Anink, Jasper J., additional, Mills, James D., additional, Jansen, Floor E., additional, Spliet, Wim G.M., additional, den Dunnen, Willfred F.A., additional, Coras, Roland, additional, Blümcke, Ingmar, additional, Paulus, Werner, additional, Scholl, Theresa, additional, Feucht, Martha, additional, Kotulska, Katarzyna, additional, Jozwiak, Sergiusz, additional, Buccoliero, Anna Maria, additional, Caporalini, Chiara, additional, Giordano, Flavio, additional, Genitori, Lorenzo, additional, Söylemezoğlu, Figen, additional, Pimentel, José, additional, Nellist, Mark, additional, Schouten-van Meeteren, Antoinette Y.N., additional, Nag, Anwesha, additional, Mühlebner, Angelika, additional, Kwiatkowski, David J., additional, and Aronica, Eleonora, additional

Published
2017
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32. Prevalence and Risk Factors of Early Endocrine Disorders in Childhood Brain Tumor Survivors: A Nationwide, Multicenter Study

Author

Clement, Sarah C., primary, Schouten-van Meeteren, Antoinette Y.N., additional, Boot, Annemieke M., additional, Claahsen-van der Grinten, Hedy L., additional, Granzen, Bernd, additional, Sen Han, K., additional, Janssens, Geert O., additional, Michiels, Erna M., additional, van Trotsenburg, A.S. Paul, additional, Vandertop, W. Peter, additional, van Vuurden, Dannis G., additional, Kremer, Leontien C.M., additional, Caron, Hubert N., additional, and van Santen, Hanneke M., additional

Published
2016
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33. Real-world implementation of electronic patient-reported outcomes in outpatient pediatric cancer care

Author

Schepers, Sasja A., primary, Sint Nicolaas, Simone M., additional, Haverman, Lotte, additional, Wensing, Michel, additional, Schouten van Meeteren, Antoinette Y.N., additional, Veening, Margreet A., additional, Caron, Huib N., additional, Hoogerbrugge, Peter M., additional, Kaspers, Gertjan J.L., additional, Verhaak, Christianne M., additional, and Grootenhuis, Martha A., additional

Published
2016
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35. Real-world implementation of electronic patient-reported outcomes in outpatient pediatric cancer care.

Author

Schepers, Sasja A., Sint Nicolaas, Simone M., Haverman, Lotte, Wensing, Michel, Schouten van Meeteren, Antoinette Y.N., Veening, Margreet A., Caron, Huib N., Hoogerbrugge, Peter M., Kaspers, Gertjan J.L., Verhaak, Christianne M., and Grootenhuis, Martha A.

Subjects
CHILDHOOD cancer, CANCER patient care, MEDICAL personnel, CANCER diagnosis, MEDICAL innovations, TUMOR treatment, OUTPATIENT medical care, PEDIATRICS, QUESTIONNAIRES
Abstract

Objective: The KLIK method is an online tool that monitors and discusses electronic patient-reported outcomes (ePROs), which has been shown to enhance outcomes. This study aimed (1) to determine the fidelity (ie, extent to which used as intended) of the KLIK method as implemented in outpatient pediatric cancer care and (2) to study health care professional (HCP)-reported barriers and facilitators for implementation.Methods: Two hundred five children with newly diagnosed cancer (enrollment rate 85%) participated. At 1 (T1), 3 (T2), and 6 (T3) months after diagnosis, patients (8-18 years) or parents (of patients 0-7 years) completed health-related quality of life (HRQoL) questionnaires, which were transformed into an ePROfile and discussed by their HCP during consultations. Fidelity was determined by the following: percentage of website registrations, HRQoL questionnaires completed, and ePROfiles discussed. Implementation determinants were assessed with HCPs after the final T3 with the Measurement Instrument for Determinants of Innovations.Results: Depending on the time point (T1-T3), fidelity was 86% to 89% for website registration, 66-85% for completed HRQoL questionnaires, and 56% to 62% for ePROfile discussion. Barriers were mainly related to organizational issues (eg, organizational change) and less frequently to users (eg, motivation to comply) or the intervention (compatibility). Facilitators were related to the user (eg, positive outcome expectations) and intervention (simplicity) but not to the organization.Conclusions: When implementing ePROs in outpatient pediatric oncology practice, HCPs report determinants that influence ePRO integration. To improve implementation and outcomes, tailored organizational (eg, formal ratification by management and time) and specific local (eg, individualized assessments) strategies should be developed to achieve optimal ePRO discussion. [ABSTRACT FROM AUTHOR]

Published
2017
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36. LOGGIC/FIREFLY-2: A phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration.

Author

van Tilburg, Cornelis Martinus, Kilburn, Lindsay Baker, Crotty, Erin, Smith, Amy Amundson, Perreault, Sébastien, Franson, Andrea Flynn, Jabado, Nada, Hoffman, Lindsey M., Schmidt, Rene, Schouten-van Meeteren, Antoinette Y.N., Sehestedt, Astrid, Opocher, Enrico, Hernáiz Driever, Pablo, Avula, Shivaram, Ziegler, David Simon, Qiu, Jiaheng, Tsao, Li-Pen, Manley, Peter, Hargrave, Darren R., and Witt, Olaf

Published
2023
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40. Survival prediction model of children with diffuse intrinsic pontine glioma based on clinical and radiological criteria

Author

Jansen, Marc H., primary, Veldhuijzen van Zanten, Sophie E., additional, Sanchez Aliaga, Esther, additional, Heymans, Martijn W., additional, Warmuth-Metz, Monika, additional, Hargrave, Darren, additional, van der Hoeven, Erica J., additional, Gidding, Corrie E., additional, de Bont, Eveline S., additional, Eshghi, Omid S., additional, Reddingius, Roel, additional, Peeters, Cacha M., additional, Schouten-van Meeteren, Antoinette Y.N., additional, Gooskens, Rob H.J., additional, Granzen, Bernd, additional, Paardekooper, Gabriel M., additional, Janssens, Geert O., additional, Noske, David P., additional, Barkhof, Frederik, additional, Kramm, Christof M., additional, Vandertop, W. Peter, additional, Kaspers, Gertjan J., additional, and van Vuurden, Dannis G., additional

Published
2014
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41. Dose-Effect Relationships for Adverse Events After Cranial Radiation Therapy in Long-term Childhood Cancer Survivors

Author

van Dijk, Irma W.E.M., primary, Cardous-Ubbink, Mathilde C., additional, van der Pal, Helena J.H., additional, Heinen, Richard C., additional, van Leeuwen, Flora E., additional, Oldenburger, Foppe, additional, van Os, Rob M., additional, Ronckers, Cécile M., additional, Schouten–van Meeteren, Antoinette Y.N., additional, Caron, Huib N., additional, Koning, Caro C.E., additional, and Kremer, Leontien C.M., additional

Published
2013
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44. Author reply

Author

Moll, Annette C, primary, Imhof, Saskia M, additional, Schouten-Van Meeteren, Antoinette Y.N, additional, Kuik, Dirk J, additional, Hofman, Pieter, additional, and Boers, Maarten, additional

Published
2002
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46. Survival prediction model of children with diffuse intrinsic pontine glioma based on clinical and radiological criteria.

Author

Jansen, Marc H., Veldhuijzen van Zanten, Sophie E., Sanchez Aliaga, Esther, Heymans, Martijn W., Warmuth-Metz, Monika, Hargrave, Darren, van der Hoeven, Erica J., Gidding, Corrie E., de Bont, Eveline S., Eshghi, Omid S., Reddingius, Roel, Peeters, Cacha M., Schouten-van Meeteren, Antoinette Y.N., Gooskens, Rob H.J., Granzen, Bernd, Paardekooper, Gabriel M., Janssens, Geert O., Noske, David P., Barkhof, Frederik, and Kramm, Christof M.

Published
2015
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48. Chemoreduction for Retinoblastoma.

Author

Moll, Annette C., Imhof, Saskia M., Schouten-van Meeteren, Antoinette Y.N., Boers, Maarten, van Leeuwen, Flora, and Hofman, Pieter

Subjects
RETINOBLASTOMA, INTRACRANIAL tumors, THERAPEUTICS, DRUG therapy, RESEARCH
Abstract

Discusses methods of prevention of intracranial neuroblastic malignancy by means of chemoreduction of retinoblastoma. Reasons for decline in the incidence of pinealoblastoma; Assertion of authors that chemotherapy does not prevents but only postpones the formation of retinoblastoma; Possible causes behind triggering of pinealoblastoma in patients with familial hereditary retinoblastoma.

Published
2003
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