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The article explores the acknowledgment of the four-color conjecture in the study of ancient paintings. Topics discussed include the conceptualization of the four-color problem by mathematician Francis Guthrie, the presence of the colors yellow, brown, red, and black in prehistoric cave paintings of the Upper Palaeolithic period, and observations on the use of four colours by ancient Greek painter Apelles.

The article focuses on art historian Ernst Gombrich's works on the psychology of pictorial representation which formed the basis for his seminal work "Art and Illusion." Topics covered include his explanation for the so-called Mona Lisa effect, several concerns on his claim that the phenomenon is inevitable, and the increasing interest of experimental psychologists and neuroscientists in the phenomenon.

On the other hand, neurologists will not be unduly concerned whether migraines can be considered an illness or a disease, nor whether a patient with migraine can - or ever should - be called a migraineur. Graph: Migraine, Words and Fiction By Joost Haan Cambridge Scholars Publishing, 2022 ISBN: 1-5275-8359-7 ISBN13: 978-1-5275-8359-7 £67.99 This book is a complex work which makes considerable demands on its readers. That doctors nevertheless should believe patients, despite negative tests, is a theme thoroughly familiar to all, but, as far as I know, far from familiar to neurologists is that 'many migraine-sufferers feel guilty for having migraine without "signs"' (p.167). [Extracted from the article]