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649 results on '"Scholz, Jens"'

1. Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) – short version

Author

DAS-Taskforce, Baron, Ralf, Binder, Andreas, Biniek, Rolf, Braune, Stephan, Buerkle, Hartmut, Dall, Peter, Demirakca, Sueha, Eckardt, Rahel, Eggers, Verena, Eichler, Ingolf, Fietze, Ingo, Freys, Stephan, Fründ, Andreas, Garten, Lars, Gohrbandt, Bernhard, Harth, Irene, Hartl, Wolfgang, Heppner, Hans-Jürgen, Horter, Johannes, Huth, Ralf, Janssens, Uwe, Jungk, Christine, Kaeuper, Kristin Maria, Kessler, Paul, Kleinschmidt, Stefan, Kochanek, Matthias, Kumpf, Matthias, Meiser, Andreas, Mueller, Anika, Orth, Maritta, Putensen, Christian, Roth, Bernd, Schaefer, Michael, Schaefers, Rainhild, Schellongowski, Peter, Schindler, Monika, Schmitt, Reinhard, Scholz, Jens, Schroeder, Stefan, Schwarzmann, Gerhard, Spies, Claudia, Stingele, Robert, Tonner, Peter, Trieschmann, Uwe, Tryba, Michael, Wappler, Frank, Waydhas, Christian, Weiss, Bjoern, and Weisshaar, Guido

Subjects
guideline, evidence, analgesia, sedation, delirium, anxiety, stress, sleep, monitoring, treatment, intensive care, critical care, Germany, Medicine
Abstract

In 2010, under the guidance of the DGAI (German Society of Anaesthesiology and Intensive Care Medicine) and DIVI (German Interdisciplinary Association for Intensive Care and Emergency Medicine), twelve German medical societies published the “Evidence- and Consensus-based Guidelines on the Management of Analgesia, Sedation and Delirium in Intensive Care”. Since then, several new studies and publications have considerably increased the body of evidence, including the new recommendations from the American College of Critical Care Medicine (ACCM) in conjunction with Society of Critical Care Medicine (SCCM) and American Society of Health-System Pharmacists (ASHP) from 2013. For this update, a major restructuring and extension of the guidelines were needed in order to cover new aspects of treatment, such as sleep and anxiety management. The literature was systematically searched and evaluated using the criteria of the Oxford Center of Evidence Based Medicine. The body of evidence used to formulate these recommendations was reviewed and approved by representatives of 17 national societies. Three grades of recommendation were used as follows: Grade “A” (strong recommendation), Grade “B” (recommendation) and Grade “0” (open recommendation). The result is a comprehensive, interdisciplinary, evidence and consensus-based set of level 3 guidelines. This publication was designed for all ICU professionals, and takes into account all critically ill patient populations. It represents a guide to symptom-oriented prevention, diagnosis, and treatment of delirium, anxiety, stress, and protocol-based analgesia, sedation, and sleep-management in intensive care medicine.

Published
2015
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2. Evidence and consensus-based German guidelines for the management of analgesia, sedation and delirium in intensive care – short version

Author

Kleinschmidt, Stefan, Koppert, Wolfgang, Kessler, Paul, Huth, Ralf, Hartl, Wolfgang, Haase, Ulrike, Garten, Lars, Engelmann, Lothar, Eichler, Ingolf, Eggers, Verena, Dictus, Christine, Dall, Peter, Bürkle, Hartmut, Biniek, Rolf, Bäsell, Katrin, Baron, Ralf, Heymann, Anja, Martin, Jörg, Kretz, Franz-Josef, Laubenthal, Heinz, Marggraf, Guenter, Meiser, Andreas, Neugebauer, Edmund, Neuhaus, Ulrike, Putensen, Christian, Quintel, Michael, Reske, Alexander, Roth, Bernard, Scholz, Jens, Schröder, Stefan, Schreiter, Dierk, Schüttler, Jürgen, Schwarzmann, Gerhard, Stingele, Robert, Tonner, Peter, Tränkle, Philip, Treede, Rolf Detlef, Trupkovic, Tomislav, Tryba, Michael, Wappler, Frank, Waydhas, Christian, and Spies, Claudia

Subjects
guideline, evidence, analgesia, sedation, delirium, monitoring, treatment, intensive care, Medicine
Abstract

Targeted monitoring of analgesia, sedation and delirium, as well as their appropriate management in critically ill patients is a standard of care in intensive care medicine. With the undisputed advantages of goal-oriented therapy established, there was a need to develop our own guidelines on analgesia and sedation in intensive care in Germany and these were published as 2nd Generation Guidelines in 2005. Through the dissemination of these guidelines in 2006, use of monitoring was shown to have improved from 8 to 51% and the use of protocol-based approaches increased to 46% (from 21%).Between 2006–2009, the existing guidelines from the DGAI (Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin) and DIVI (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin) were developed into 3rd Generation Guidelines for the securing and optimization of quality of analgesia, sedation and delirium management in the intensive care unit (ICU). In collaboration with another 10 professional societies, the literature has been reviewed using the criteria of the Oxford Center of Evidence Based Medicine. Using data from 671 reference works, text, diagrams and recommendations were drawn up. In the recommendations, Grade “A” (very strong recommendation), Grade “B” (strong recommendation) and Grade “0” (open recommendation) were agreed.As a result of this process we now have an interdisciplinary and consensus-based set of 3rd Generation Guidelines that take into account all critically illness patient populations.The use of protocols for analgesia, sedation and treatment of delirium are repeatedly demonstrated. These guidelines offer treatment recommendations for the ICU team. The implementation of scores and protocols into routine ICU practice is necessary for their success.

Published
2010

5. Perioperative and Postoperative Management

Author

Scholz, Jens, Tonner, Peter H., von Knobelsdorff, Georg, Izbicki, J. R., editor, Broering, D. C., editor, Yekebas, E. F., editor, Kutup, A., editor, Chernousov, A. F., editor, Gallinger, Y. I., editor, Bogopolski, P. M., editor, and Soehendra, N., editor

Published
2009
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9. MAid: A Robotic Wheelchair Operating in Public Environments

Author

Prassler, Erwin, Scholz, Jens, Strobel, Matthias, Fiorini, Paolo, Goos, Gerhard, editor, Hartmanis, Juris, editor, van Leeuwen, Jan, editor, Carbonell, Jaime G., editor, Siekmann, Jörg, editor, Christensen, Henrik I., editor, Bunke, Horst, editor, and Noltemeier, Hartmut, editor

Published
1999
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10. The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany

Author

Häsler, Robert, Kautz, Christian, Rehman, Ateequr, Podschun, Rainer, Gassling, Volker, Brzoska, Pius, Sherlock, Jon, Gräsner, Jan-Thorsten, Hoppenstedt, Gesine, Schubert, Sabine, Ferlinz, Astrid, Lieb, Wolfgang, Laudes, Matthias, Heinsen, Femke-Anouska, Scholz, Jens, Harmsen, Dag, Franke, Andre, Eisend, Swantje, Kunze, Thomas, Fickenscher, Helmut, Ott, Stephan, Rosenstiel, Philip, and Schreiber, Stefan

Published
2018
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28. A model of the isolated perfused rat small intestine

Author

Lautenschlager, Ingmar, Dombrowsky, Heike, Frerichs, Inez, Kuchenbecker, Solveig-Carolin, Bade, Steffen, Schultz, Holger, Zabel, Peter, Scholz, Jens, Weiler, Norbert, and Uhlig, Stefan

Subjects
Intestine, Small -- Physiological aspects, Intestine, Small -- Research, Platelet activating factor -- Physiological aspects, Biological sciences
Abstract

Intestinal edema remains a serious clinical problem, and novel approaches to study its pathophysiology are needed. It was our aim to develop a long-term stable isolated perfused rat small bowel preparation permitting analysis of vascular, luminal, interstitial, and lymphatic compartments and to demonstrate the utility of this model by studying the effects of the proinflammatory mediator platelet-activating factor (PAF). A temperature-controlled chamber with an integrated balance was designed to perfuse isolated intestines through the mesenteric artery and the gut lumen. Steroids or oxygen carriers were not needed. Functional and morphological integrity of the tissue was preserved for several hours as confirmed by oxygen consumption, venous lactate-to-pyruvate ratio, arterial and venous pH, lactose digestion and galactose uptake, intravascular and luminal pressures, maintained fluid homeostasis, gut motility, and quantitative light microscopic analysis. Administration of PAF caused typical effects such as vasoconstriction, gut atony, and loss of galactose uptake. PAF also elicited a transient loss of 20% of the perfusate liquid from the mesenteric vascular bed, two-thirds of which were transferred to the lumen. All these responses were entirely reversible. This new model provides detailed insights into the physiology of the small intestine and will allow to study fundamental processes such as fluid homeostasis, barrier functions, transport mechanisms, and immune responses in this organ. Using this model, here we show a dramatic and yet reversible response of the rat small bowel to PAF, suggesting luminal water clearance as a novel safety factor in the intestine that may be of clinical relevance. intestine physiology; fluid balance; platelet-activating factor doi: 10.1152/ajpgi.00313.2009

Published
2010

29. Welcome: Deputy Chairman – Section Surgery, Orthopedics and Anaesthesiology (17) of the Leopoldina, CEO of the University Hospital Schleswig-Holstein

Author

Scholz, Jens

Subjects
Welcome, Medicine, Conference
Abstract

Leopoldina Symposium Mission – Innovation: Telematics, eHealth and High-Definition Medicine in Patient-Centered Acute Medicine, Berlin, February 28th and 29th, 2020 - Opening, Mission – Innovation: Telematics, eHealth and High-Definition Medicine in Patient-Centered Acute Medicine, p. 11

Published
2021
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