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4. LiMeS-Lab: An Integrated Laboratory for the Development of Liquid–Metal Shield Technologies for Fusion Reactors

Author

Tanke, V. F. B., Al, R. S., Alonso van der Westen, S., Brons, S., Classen, I. G. J., van Dommelen, J. A. W., van Eck, H. J. N., Geers, M. G. D., Lopes Cardozo, N. J., van der Meiden, H. J., Orrico, C. A., van de Pol, M. J., Riepen, M., Rindt, P., de Rooij, T. P., Scholten, J., Timmer, R. H. M., Vernimmen, J. W. M., Vos, E. G. P., and Morgan, T. W.

Published
2023
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7. Cost-effectiveness of selective decontamination of the digestive tract to decrease infectious complications in colorectal cancer surgery: An analysis of the SELECT trial

Author

Abis, G.S.A., Bonjer, H.J., Tuynman, J.B., van Egmond, M., Stockmann, H.B.A.C., de Korte, N., Acherman, Y.I.Z., Oosterling, S.J., den Boer, F.C., Sonneveld, D.J.A., Budding, A.E., Poort, L., Reuvers, J.R.D., Gaikhorst, E., Ben, Â. Jornada, Scholten, J., Bosmans, J.E., and Kazemier, G.

Published
2023
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12. Challenges in QCD matter physics - The Compressed Baryonic Matter experiment at FAIR

Author

CBM Collaboration, Ablyazimov, T., Abuhoza, A., Adak, R. P., Adamczyk, M., Agarwal, K., Aggarwal, M. M., Ahammed, Z., Ahmad, F., Ahmad, N., Ahmad, S., Akindinov, A., Akishin, P., Akishina, E., Akishina, T., Akishina, V., Akram, A., Al-Turany, M., Alekseev, I., Alexandrov, E., Alexandrov, I., Amar-Youcef, S., Anđelić, M., Andreeva, O., Andrei, C., Andronic, A., Anisimov, Yu., Appelshäuser, H., Argintaru, D., Atkin, E., Avdeev, S., Averbeck, R., Azmi, M. D., Baban, V., Bach, M., Badura, E., Bähr, S., Balog, T., Balzer, M., Bao, E., Baranova, N., Barczyk, T., Bartoş, D., Bashir, S., Baszczyk, M., Batenkov, O., Baublis, V., Baznat, M., Becker, J., Becker, K. -H., Belogurov, S., Belyakov, D., Bendarouach, J., Berceanu, I., Bercuci, A., Berdnikov, A., Berdnikov, Y., Berendes, R., Berezin, G., Bergmann, C., Bertini, D., Bertini, O., Beşliu, C., Bezshyyko, O., Bhaduri, P. P., Bhasin, A., Bhati, A. K., Bhattacharjee, B., Bhattacharyya, A., Bhattacharyya, T. K., Biswas, S., Blank, T., Blau, D., Blinov, V., Blume, C., Bocharov, Yu., Book, J., Breitner, T., Brüning, U., Brzychczyk, J., Bubak, A., Büsching, H., Bus, T., Butuzov, V., Bychkov, A., Byszuk, A., Cai, Xu, Cálin, M., Cao, Ping, Caragheorgheopol, G., Carević, I., Cătănescu, V., Chakrabarti, A., Chattopadhyay, S., Chaus, A., Chen, Hongfang, Chen, LuYao, Cheng, Jianping, Chepurnov, V., Cherif, H., Chernogorov, A., Ciobanu, M. I., Claus, G., Constantin, F., Csanád, M., D'Ascenzo, N., Das, Supriya, Das, Susovan, de Cuveland, J., Debnath, B., Dementiev, D., Deng, Wendi, Deng, Zhi, Deppe, H., Deppner, I., Derenovskaya, O., Deveaux, C. A., Deveaux, M., Dey, K., Dey, M., Dillenseger, P., Dobyrn, V., Doering, D., Dong, Sheng, Dorokhov, A., Dreschmann, M., Drozd, A., Dubey, A. K., Dubnichka, S., Dubnichkova, Z., Dürr, M., Dutka, L., Dželalija, M., Elsha, V. V., Emschermann, D., Engel, H., Eremin, V., Eşanu, T., Eschke, J., Eschweiler, D., Fan, Huanhuan, Fan, Xingming, Farooq, M., Fateev, O., Feng, Shengqin, Figuli, S. P. D., Filozova, I., Finogeev, D., Fischer, P., Flemming, H., Förtsch, J., Frankenfeld, U., Friese, V., Friske, E., Fröhlich, I., Frühauf, J., Gajda, J., Galatyuk, T., Gangopadhyay, G., Chávez, C. García, Gebelein, J., Ghosh, P., Ghosh, S. K., Gläßel, S., Goffe, M., Golinka-Bezshyyko, L., Golovatyuk, V., Golovnya, S., Golovtsov, V., Golubeva, M., Golubkov, D., Ramírez, A. Gómez, Gorbunov, S., Gorokhov, S., Gottschalk, D., Gryboś, P., Grzeszczuk, A., Guber, F., Gudima, K., Gumiński, M., Gupta, A., Gusakov, Yu., Han, Dong, Hartmann, H., He, Shue, Hehner, J., Heine, N., Herghelegiu, A., Herrmann, N., Heß, B., Heuser, J. M., Himmi, A., Höhne, C., Holzmann, R., Hu, Dongdong, Huang, Guangming, Huang, Xinjie, Hutter, D., Ierusalimov, A., Ilgenfritz, E. -M., Irfan, M., Ivanischev, D., Ivanov, M., Ivanov, P., Ivanov, Valery, Ivanov, Victor, Ivanov, Vladimir, Ivashkin, A., Jaaskelainen, K., Jahan, H., Jain, V., Jakovlev, V., Janson, T., Jiang, Di, Jipa, A., Kadenko, I., Kähler, P., Kämpfer, B., Kalinin, V., Kallunkathariyil, J., Kampert, K. -H., Kaptur, E., Karabowicz, R., Karavichev, O., Karavicheva, T., Karmanov, D., Karnaukhov, V., Karpechev, E., Kasiński, K., Kasprowicz, G., Kaur, M., Kazantsev, A., Kebschull, U., Kekelidze, G., Khan, M. M., Khan, S. A., Khanzadeev, A., Khasanov, F., Khvorostukhin, A., Kirakosyan, V., Kirejczyk, M., Kiryakov, A., Kiš, M., Kisel, I., Kisel, P., Kiselev, S., Kiss, T., Klaus, P., Kłeczek, R., Klein-Bösing, Ch., Kleipa, V., Klochkov, V., Kmon, P., Koch, K., Kochenda, L., Koczoń, P., Koenig, W., Kohn, M., Kolb, B. W., Kolosova, A., Komkov, B., Korolev, M., Korolko, I., Kotte, R., Kovalchuk, A., Kowalski, S., Koziel, M., Kozlov, G., Kozlov, V., Kramarenko, V., Kravtsov, P., Krebs, E., Kreidl, C., Kres, I., Kresan, D., Kretschmar, G., Krieger, M., Kryanev, A. V., Kryshen, E., Kuc, M., Kucewicz, W., Kucher, V., Kudin, L., Kugler, A., Kumar, Ajit, Kumar, Ashwini, Kumar, L., Kunkel, J., Kurepin, A., Kurepin, N., Kurilkin, A., Kurilkin, P., Kushpil, V., Kuznetsov, S., Kyva, V., Ladygin, V., Lara, C., Larionov, P., García, A. Laso, Lavrik, E., Lazanu, I., Lebedev, A., Lebedev, S., Lebedeva, E., Lehnert, J., Lehrbach, J., Leifels, Y., Lemke, F., Li, Cheng, Li, Qiyan, Li, Xin, Li, Yuanjing, Lindenstruth, V., Linnik, B., Liu, Feng, Lobanov, I., Lobanova, E., Löchner, S., Loizeau, P. -A., Lone, S. A., Martínez, J. A. Lucio, Luo, Xiaofeng, Lymanets, A., Lyu, Pengfei, Maevskaya, A., Mahajan, S., Mahapatra, D. P., Mahmoud, T., Maj, P., Majka, Z., Malakhov, A., Malankin, E., Malkevich, D., Malyatina, O., Malygina, H., Mandal, M. M., Mandal, S., Manko, V., Manz, S., Garcia, A. M. Marin, Markert, J., Masciocchi, S., Matulewicz, T., Meder, L., Merkin, M., Mialkovski, V., Michel, J., Miftakhov, N., Mik, L., Mikhailov, K., Mikhaylov, V., Milanović, B., Militsija, V., Miskowiec, D., Momot, I., Morhardt, T., Morozov, S., Müller, W. F. J., Müntz, C., Mukherjee, S., Castillo, C. E. Muńoz, Murin, Yu., Najman, R., Nandi, C., Nandy, E., Naumann, L., Nayak, T., Nedosekin, A., Negi, V. S., Niebur, W., Nikulin, V., Normanov, D., Oancea, A., Oh, Kunsu, Onishchuk, Yu., Ososkov, G., Otfinowski, P., Ovcharenko, E., Pal, S., Panasenko, I., Panda, N. R., Parzhitskiy, S., Patel, V., Pauly, C., Penschuck, M., Peshekhonov, D., Peshekhonov, V., Petráček, V., Petri, M., Petriş, M., Petrovici, A., Petrovici, M., Petrovskiy, A., Petukhov, O., Pfeifer, D., Piasecki, K., Pieper, J., Pietraszko, J., Płaneta, R., Plotnikov, V., Plujko, V., Pluta, J., Pop, A., Pospisil, V., Poźniak, K., Prakash, A., Prasad, S. K., Prokudin, M., Pshenichnov, I., Pugach, M., Pugatch, V., Querchfeld, S., Rabtsun, S., Radulescu, L., Raha, S., Rami, F., Raniwala, R., Raniwala, S., Raportirenko, A., Rautenberg, J., Rauza, J., Ray, R., Razin, S., Reichelt, P., Reinecke, S., Reinefeld, A., Reshetin, A., Ristea, C., Ristea, O., Rodriguez, A. Rodriguez, Roether, F., Romaniuk, R., Rost, A., Rostchin, E., Rostovtseva, I., Roy, Amitava, Roy, Ankhi, Rożynek, J., Ryabov, Yu., Sadovsky, A., Sahoo, R., Sahu, P. K., Sahu, S. K., Saini, J., Samanta, S., Sambyal, S. S., Samsonov, V., Rosado, J. Sánchez, Sander, O., Sarangi, S., Satława, T., Sau, S., Saveliev, V., Schatral, S., Schiaua, C., Schintke, F., Schmidt, C. J., Schmidt, H. R., Schmidt, K., Scholten, J., Schweda, K., Seck, F., Seddiki, S., Selyuzhenkov, I., Semennikov, A., Senger, A., Senger, P., Shabanov, A., Shabunov, A., Shao, Ming, Sheremetiev, A. D., Shi, Shusu, Shumeiko, N., Shumikhin, V., Sibiryak, I., Sikora, B., Simakov, A., Simon, C., Simons, C., Singaraju, R. N., Singh, A. K., Singh, B. K., Singh, C. P., Singhal, V., Singla, M., Sitzmann, P., Siwek-Wilczyńska, K., Škoda, L., Skwira-Chalot, I., Som, I., Song, Guofeng, Song, Jihye, Sosin, Z., Soyk, D., Staszel, P., Strikhanov, M., Strohauer, S., Stroth, J., Sturm, C., Sultanov, R., Sun, Yongjie, Svirida, D., Svoboda, O., Szabó, A., Szczygieł, R., Talukdar, R., Tang, Zebo, Tanha, M., Tarasiuk, J., Tarassenkova, O., Târzilă, M. -G., Teklishyn, M., Tischler, T., Tlustý, P., Tölyhi, T., Toia, A., Topil'skaya, N., Träger, M., Tripathy, S., Tsakov, I., Tsyupa, Yu., Turowiecki, A., Tuturas, N. G., Uhlig, F., Usenko, E., Valin, I., Varga, D., Vassiliev, I., Vasylyev, O., Verbitskaya, E., Verhoeven, W., Veshikov, A., Visinka, R., Viyogi, Y. P., Volkov, S., Volochniuk, A., Vorobiev, A., Voronin, Aleksey, Voronin, Alexander, Vovchenko, V., Vznuzdaev, M., Wang, Dong, Wang, Xi-Wei, Wang, Yaping, Wang, Yi, Weber, M., Wendisch, C., Wessels, J. P., Wiebusch, M., Wiechula, J., Wielanek, D., Wieloch, A., Wilms, A., Winckler, N., Winter, M., Wiśniewski, K., Wolf, Gy., Won, Sanguk, Wu, Ke-Jun, Wüstenfeld, J., Xiang, Changzhou, Xu, Nu, Yang, Junfeng, Yang, Rongxing, Yin, Zhongbao, Yoo, In-Kwon, Yuldashev, B., Yushmanov, I., Zabołotny, W., Zaitsev, Yu., Zamiatin, N. I., Zanevsky, Yu., Zhalov, M., Zhang, Yifei, Zhang, Yu, Zhao, Lei, Zheng, Jiajun, Zheng, Sheng, Zhou, Daicui, Zhou, Jing, Zhu, Xianglei, Zinchenko, A., Zipper, W., Żoładź, M., Zrelov, P., Zryuev, V., Zumbruch, P., and Zyzak, M.

Subjects
Nuclear Experiment
Abstract

Substantial experimental and theoretical efforts worldwide are devoted to explore the phase diagram of strongly interacting matter. At LHC and top RHIC energies, QCD matter is studied at very high temperatures and nearly vanishing net-baryon densities. There is evidence that a Quark-Gluon-Plasma (QGP) was created at experiments at RHIC and LHC. The transition from the QGP back to the hadron gas is found to be a smooth cross over. For larger net-baryon densities and lower temperatures, it is expected that the QCD phase diagram exhibits a rich structure, such as a first-order phase transition between hadronic and partonic matter which terminates in a critical point, or exotic phases like quarkyonic matter. The discovery of these landmarks would be a breakthrough in our understanding of the strong interaction and is therefore in the focus of various high-energy heavy-ion research programs. The Compressed Baryonic Matter (CBM) experiment at FAIR will play a unique role in the exploration of the QCD phase diagram in the region of high net-baryon densities, because it is designed to run at unprecedented interaction rates. High-rate operation is the key prerequisite for high-precision measurements of multi-differential observables and of rare diagnostic probes which are sensitive to the dense phase of the nuclear fireball. The goal of the CBM experiment at SIS100 (sqrt(s_NN) = 2.7 - 4.9 GeV) is to discover fundamental properties of QCD matter: the phase structure at large baryon-chemical potentials (mu_B > 500 MeV), effects of chiral symmetry, and the equation-of-state at high density as it is expected to occur in the core of neutron stars. In this article, we review the motivation for and the physics programme of CBM, including activities before the start of data taking in 2022, in the context of the worldwide efforts to explore high-density QCD matter., Comment: 15 pages, 11 figures. Published in European Physical Journal A

Published
2016
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16. Chrysanthemum Morifolium Extract And Ascorbic Acid-2-Glucoside (AA2G) Blend Inhibits UVA-Induced Delayed Cyclobutane Pyrimidine Dimer (CPD) Production In Melanocytes

Author

Yim S, Lee J, Jo H, Scholten J, Willingham R, Nicoll J, and Baswan SM

Subjects
cellular dna photodamage, chrysanthemum morifolium extract, ascorbic acid-2-glucoside (aa2g), dna damage, cyclobutane pyrimidine dimers (cpd), dark cpd, melanocytes, uv radiation, Dermatology, RL1-803
Abstract

Sunghan Yim,1 Jeesun Lee,2 Hae Jo,2 Jeff Scholten,1 Ryan Willingham,3 Jim Nicoll,3 Sudhir M Baswan4 1Analytical Sciences R&D, Amway Corporation, Ada, MI, USA; 2Asia Innovation Center, Global Discovery R&D, Amway Corporation, Seoul, South Korea; 3Zen-Bio, Inc., Research Triangle Park, Durham, NC, USA; 4Global Discovery R&D, Amway Corporation, Ada, MI, USACorrespondence: Sunghan YimAmway Corporation, 7575 Fulton Street E, Ada, MI 49355, USATel +1 616 787 1458Fax +1 616 787 4466Email sunghan.yim@amway.comBackground: Solar ultraviolet radiation (UV) induces DNA damages in skin via direct absorption of UVB or indirectly by photosensitization mediated through UVA. Recent findings have revealed that UVA induces cyclobutane pyrimidine dimer (CPD) generation via chemiexcitation in melanocytes hours after the exposure. This UVA-induced delayed CPD (dark CPD) constitutes the majority of CPD in melanocytes. These findings indicate that sun light can damage the skin hours after the exposure, suggesting the need for skin care products post sun exposure. The main objective of this study was to investigate whether a blend of Chrysanthemum Morifolium flower extract (Chrys) and vitamin C derivative, Ascorbic Acid-2-Glucoside (AA2G), can provide protective effects against reactive oxygen species, melanin formation and UVA-induced dark CPD.Methods: Intracellular ROS levels were measured in epidermal keratinocytes using DHR123 dye. Melanogenesis inhibition efficacy was determined using B16 cells. As for the dark CPD measurement, Melan-a cells were treated with or without actives for 6 days, then irradiated with UVA at various doses. Cells were exposed with anti-CPD mAb followed by secondary Ab. CPD levels were determined by measuring fluorescent intensity using a high content imaging analysis.Results: Chrys, AA2G and their blend at various concentrations demonstrated ROS scavenging activity. Though Chrys alone did not show significant melanogenesis inhibition in B16 assay, the blend of Chrys with AA2G demonstrated additive effects in comparison with AA2G alone. The blend of AA2G and Chrys at various concentrations exhibited enhanced efficacy for inhibiting dark CPD compared to AA2G alone.Conclusion: The results from this study indicate that the use of natural antioxidant, Chrys in combination with AA2G, provides protection against UVA-induced delayed CPD formation by enhancing ROS scavenging activity and melanogenesis inhibition. These findings could potentially be applied for formulating post-sun exposure skin care products, possibly extending to evening-after care products.Keywords: cellular DNA photodamage, chrysanthemum morifolium extract, ascorbic acid-2-glucoside, AA2G, DNA damage, cyclobutane pyrimidine dimers, CPD, dark CPD, melanocytes

Published
2019

20. Environmental life cycle assessment of production of the high intensity sweetener steviol glycosides from Stevia rebaudiana leaf grown in Europe: The SWEET project

Author

Suckling, John, Morse, S, Murphy, R, Astley, S, Halford, J C G, Harrold, J A, Le-Bail, A, Koukouna, E, Musinovic, H, Perret, J, Raben, Anne, Roe, M, Scholten, J, Scott, C, Stamatis, C, Westbroek, C, Suckling, John, Morse, S, Murphy, R, Astley, S, Halford, J C G, Harrold, J A, Le-Bail, A, Koukouna, E, Musinovic, H, Perret, J, Raben, Anne, Roe, M, Scholten, J, Scott, C, Stamatis, C, and Westbroek, C

Abstract

Purpose: There is an increasing interest in the use of non-nutritive sweeteners to replace added sugar in food and beverage products for reasons of improving consumer health. Much work has been done to understand safety of sweeteners, but very little on sustainability. To address that gap, this study presents the results of a life cycle assessment (LCA) of production of rebaudioside A 60%, 95% pure (RA60) steviol glycoside mix from Stevia rebaudiana leaf grown in Europe.Methods: An attributional cradle-to-factory-gate life cycle assessment was conducted on growing of stevia leaves and extraction of steviol glycosides in Europe. Primary data were used from a case study supply chain. Results are reported in impact categories from the ReCiPe 2016 (H) method, with focus given to global warming potential, freshwater eutrophication, water consumption, and land use. Impacts are expressed both in terms of production mass and sweetness equivalence, a common metric for understanding high intensity sweetener potency. Sweetness equivalence of RA60 is typically 200 to 300 times that of sugar. Comparison of environmental impact is made to sugar (sucrose) produced from both cane and beets. The research is part of the EU project SWEET (sweeteners and sweetness enhancers: impact on health, obesity, safety, and sustainability).Results and discussion: Global warming potential for production of RA60 was found to be 20.25 kgCO2-eq/kgRA60 on a mass basis and 0.081 kgCO2-eq/kgSE on a sweetness equivalence basis. Field production of stevia leaves was found to be the main source of impact for most impact categories, and for all four focus categories. Extraction of the RA60 was the main source of impact for the others. Leaf processing and seedling propagation were minor contributors to life cycle impact. Removal of international transport from the supply chain reduced global warming potential by 18.8%. C

Published
2023

21. Life cycle assessment of the sweetness enhancer thaumatin (E957) produced from Thaumatococcus daniellii fruit foraged from West Africa: The SWEET project

Author

Suckling, J, Morse, S, Murphy, R, Astley, S, Boy, C, Halford, J C G, Harrold, J A, Le-Bail, A, Koukouna, E, Musinovic, H, Raben, Anne, Roe, M, Scholten, J, Scott, C, Westbroek, C, Suckling, J, Morse, S, Murphy, R, Astley, S, Boy, C, Halford, J C G, Harrold, J A, Le-Bail, A, Koukouna, E, Musinovic, H, Raben, Anne, Roe, M, Scholten, J, Scott, C, and Westbroek, C

Abstract

Replacing added sugar with non-nutritive sweeteners and sweetness enhancers is of increasing interest due to the negative health effects of excess sugar consumption. Much has been done to understand health and safety of such sweetening additives, but little on their sustainability. This study, part of the Horizon 2020 SWEET project, presents results from the first life cycle assessment of the sweetness enhancer thaumatin, produced from Thaumatococcus daniellii fruit, from forests in West Africa and extracted in the United Kingdom. Thaumatin is used in formulations to increase perceived sweetness of added sugar, allowing some to be removed. Environmental impact is reported for multiple impact categories from the ReCiPe 2016 (H) method, focusing on global warming potential, land use, water consumption, and freshwater eutrophication. Impacts are expressed in terms of product mass and sweetness equivalence. Global warming potential for production of thaumatin is found to be 719.2 kgCO2-eq/kg. When thaumatin replaces 20% of added sugar, environmental impact for a given sweetness is found to reduce by an average of 19.4% across all impact categories. International transport is a major contributor to global warming potential, as is aril removal from the fruit to freshwater eutrophication and water use, and fruit foraging to land use. However, land use is identified as a key area of future research to improve uncertainty in the data. Results show that thaumatin can be used to reduce the environmental impact of providing sweet taste in food and beverage products.

Published
2023

22. LiMeS-Lab: An Integrated Laboratory for the Development of Liquid–Metal Shield Technologies for Fusion Reactors

Author

Tanke, V. F.B., Al, R. S., Alonso van der Westen, S., Brons, S., Classen, I. G.J., van Dommelen, J. A.W., van Eck, H. J.N., Geers, M. G.D., Lopes Cardozo, N. J., van der Meiden, H. J., Orrico, C. A., van de Pol, M. J., Riepen, M., Rindt, P., de Rooij, T. P., Scholten, J., Timmer, R. H.M., Vernimmen, J. W.M., Vos, E. G.P., Morgan, T. W., Tanke, V. F.B., Al, R. S., Alonso van der Westen, S., Brons, S., Classen, I. G.J., van Dommelen, J. A.W., van Eck, H. J.N., Geers, M. G.D., Lopes Cardozo, N. J., van der Meiden, H. J., Orrico, C. A., van de Pol, M. J., Riepen, M., Rindt, P., de Rooij, T. P., Scholten, J., Timmer, R. H.M., Vernimmen, J. W.M., Vos, E. G.P., and Morgan, T. W.

Abstract

The liquid metal shield laboratory (LiMeS-Lab) will provide the infrastructure to develop, test, and compare liquid metal divertor designs for future fusion reactors. The main research topics of LiMeS-lab will be liquid metal interactions with the substrate material of the divertor, the continuous circulation and capillary refilling of the liquid metal during intense plasma heat loading and the retention of plasma particles in the liquid metal. To facilitate the research, four new devices are in development at the Dutch Institute for Fundamental Energy Research and the Eindhoven University of Technology: LiMeS-AM: a custom metal 3D printer based on powder bed fusion; LiMeS-Wetting, a plasma device to study the wetting of liquid metals on various substrates with different surface treatments; LiMeS-PSI, a linear plasma generator specifically adapted to operate continuous liquid metal loops. Special diagnostic protection will also be implemented to perform measurements in long duration shots without being affected by the liquid metal vapor; LiMeS-TDS, a thermal desorption spectroscopy system to characterize deuterium retention in a metal vapor environment. Each of these devices has specific challenges due to the presence and deposition of metal vapors that need to be addressed in order to function. In this paper, an overview of LiMeS-Lab will be given and the conceptual designs of the last three devices will be presented.

Published
2023

23. Ideas and perspectives: Land–ocean connectivity through groundwater

Author

Arévalo-Martínez, D.L., Haroon, A., Bange, H.W., Erkul, E., Jegen, M., Moosdorf, N., Schneider von Deimling, J., Berndt, C., Böttcher, M.E., Hoffmann, J., Liebetrau, V., Mallast, Ulf, Massmann, G., Micallef, A., Michael, H.A., Paasche, Hendrik, Rabbel, W., Santos, I., Scholten, J., Schwalenberg, K., Szymczycha, B., Thomas, A.T., Virtasalo, J.J., Waska, H., Weymer, B.A., Arévalo-Martínez, D.L., Haroon, A., Bange, H.W., Erkul, E., Jegen, M., Moosdorf, N., Schneider von Deimling, J., Berndt, C., Böttcher, M.E., Hoffmann, J., Liebetrau, V., Mallast, Ulf, Massmann, G., Micallef, A., Michael, H.A., Paasche, Hendrik, Rabbel, W., Santos, I., Scholten, J., Schwalenberg, K., Szymczycha, B., Thomas, A.T., Virtasalo, J.J., Waska, H., and Weymer, B.A.

Abstract

For millennia, humans have gravitated towards coastlines for their resource potential and as geopolitical centres for global trade. A basic requirement ensuring water security for coastal communities relies on a delicate balance between the supply and demand of potable water. The interaction between freshwater and saltwater in coastal settings is, therefore, complicated by both natural and human-driven environmental changes at the land–sea interface. In particular, ongoing sea-level rise, warming and deoxygenation might exacerbate such perturbations. In this context, an improved understanding of the nature and variability of groundwater fluxes across the land–sea continuum is timely yet remains out of reach. The flow of terrestrial groundwater across the coastal transition zone and the extent of freshened groundwater below the present-day seafloor are receiving increased attention in marine and coastal sciences because they likely represent a significant yet highly uncertain component of (bio)geochemical budgets and because of the emerging interest in the potential use of offshore freshened groundwater as a resource. At the same time, “reverse” groundwater flux from offshore to onshore is of prevalent socio-economic interest, as terrestrial groundwater resources are continuously pressured by over-pumping and seawater intrusion in many coastal regions worldwide. An accurate assessment of the land–ocean connectivity through groundwater and its potential responses to future anthropogenic activities and climate change will require a multidisciplinary approach combining the expertise of geophysicists, hydrogeologists, (bio)geochemists and modellers. Such joint activities will lay the scientific basis for better understanding the role of groundwater in societally relevant issues such as climate change, pollution and the environmental status of the coastal oceans within the framework of the United Nations Sustainable Development Goals. Here, we present our perspectives on

Published
2023

24. An updated identification guide to the species of Amorphophallus (Araceae): new synonyms and a set of global dichotomous keys

Author

Scholten, J. and Scholten, J.

Abstract

This work presents updated dichotomous keys to the Amorphophallus (Araceae) species of the world based on morphological characters of the inflorescence. It is a compilation of data derived from herbarium specimens, living specimens, protologues, and following papers outlining taxonomic updates to the genus. Three new synonyms are proposed and a general key including 239 species of Amorphophallus distributed across the African, Asian, and Australian continents is included. Ten additional subkeys are provided by geographical subregion, making identification streamlined if the locality of the specimen is known. The aim of this paper is to make identification of Amorphophallus species accessible through a single manuscript, serving not only the research sector, but also citizen science. This guide provides a rapid and ac

Published
2023
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25. Environmental life cycle assessment of production of the non-nutritive sweetener sucralose (E955) derived from cane sugar produced in the United States of America:The SWEET project

Author

Blenkley, E., Suckling, J., Morse, S., Murphy, R., Raats, M., Astley, S., Halford, J. C. G., Harrold, J. A., Le-Bail, A., Koukouna, E., Musinovic, H., Raben, A., Roe, M., Scholten, J., Scott, C., Westbroek, C., Blenkley, E., Suckling, J., Morse, S., Murphy, R., Raats, M., Astley, S., Halford, J. C. G., Harrold, J. A., Le-Bail, A., Koukouna, E., Musinovic, H., Raben, A., Roe, M., Scholten, J., Scott, C., and Westbroek, C.

Abstract

Purpose: There is increasing concern about the detrimental health effects of added sugar in food and drink products. Sweeteners are seen as a viable alternative. Much work has been done on health and safety of using sweeteners as a replacement for added sugar, but very little on their sustainability. This work aims to bridge that gap with a life cycle assessment (LCA) of sucralose derived from cane sugar grown in the United States of America (USA). Methods: An attributional, cradle-to-gate LCA was conducted on sucralose production in the USA. Primary data were derived from literature for the chlorination process, and all other data from background sources. Results are reported via the ReCiPe 2016 (H) method, with focus given to land use, global warming potential (GWP), marine eutrophication, mineral resource scarcity, and water consumption. Because sucralose has a much greater perceived sweetness than sugar, impacts are expressed both in absolute terms of 1 kg mass and in relative sweetness equivalence terms to 1 kg sugar. Scenario modelling explores the sensitivity of the LCA results to change in key parameters. This research was conducted as part of the EU Horizon 2020 project SWEET (Sweeteners and sweetness enhancers: Impact on health, obesity, safety and sustainability). Results and discussion: GWP for 1 kg sucralose was calculated to be 71.83 kgCO2-eq/kg (sugar from sugarcane is 0.77 kgCO2-eq/kg). However, on a sweetness equivalence basis, GWP of sucralose reduces to 0.12 kgCO2-eq/kgSE. Production of reagents was the main contributor to impact across most impact categories. Sugar (starting material for sucralose production) was not a majority contributor to any impact category, and changing the source of sugar has little effect upon net impact (average 2.0% variation). Instead, uncertainty in reference data is a greater source of variability: reagent use optimization reduces average impact of sucralose production b

Published
2023

26. Environmental life cycle assessment of production of the non-nutritive sweeteners aspartame (E951) and neotame (E961) from chemical processes:The SWEET project

Author

Suckling, J., Morse, S., Murphy, R., Raats, M., Astley, S., Halford, J. C.G., Harrold, J. A., Le-Bail, A., Koukouna, E., Musinovic, H., Raben, A., Roe, M., Scholten, J., Scott, C., Westbroek, C., Suckling, J., Morse, S., Murphy, R., Raats, M., Astley, S., Halford, J. C.G., Harrold, J. A., Le-Bail, A., Koukouna, E., Musinovic, H., Raben, A., Roe, M., Scholten, J., Scott, C., and Westbroek, C.

Abstract

Consumption of added sugar is a cause of concern due to links with non-communicable diseases. Non-nutritive sweeteners (NNSs) are increasingly seen as a viable alternative. Health and safety of NNSs are well studied, but not their environmental impact. In this study the environmental impact of NNSs aspartame and neotame are presented. This is the first such study attempting to quantify environmental impact of neotame. Life cycle data are derived from literature, alongside stoichiometric reaction equations and resulting heat changes. Global warming potential (GWP) of 1 kg aspartame is found to be 29.25 kgCO2-eq/kg, and 1 kg neotame to be 43.42 kgCO2-eq/kg. It is found that both NNSs have great potential to replace the sweetness of added sugar with reduced environmental impact, e.g., GWP of neotame is found to be 0.4–0.7%, and aspartame 10.5–18.4%, of an equivalent sweetness for sucrose. This study demonstrates that environmental impact of the additional resources required to make neotame from aspartame are more than offset by the increase in perceived sweetness, from 200 to 8000-times. It is shown that there are significant uncertainties related to life cycle inventory data and data derivation method. Therefore, this work further highlights the difficulties of conducting a life cycle assessment of highly refined industrial food additives and the need for good industrial collaboration in obtaining data.

Published
2023

28. Challenges in QCD matter physics --The scientific programme of the Compressed Baryonic Matter experiment at FAIR

Author

Ablyazimov, T., Abuhoza, A., Adak, R. P., Adamczyk, M., Agarwal, K., Aggarwal, M. M., Ahammed, Z., Ahmad, F., Ahmad, N., Ahmad, S., Akindinov, A., Akishin, P., Akishina, E., Akishina, T., Akishina, V., Akram, A., Al-Turany, M., Alekseev, I., Alexandrov, E., Alexandrov, I., Amar-Youcef, S., Anđelić, M., Andreeva, O., Andrei, C., Andronic, A., Anisimov, Yu., Appelshäuser, H., Argintaru, D., Atkin, E., Avdeev, S., Averbeck, R., Azmi, M. D., Baban, V., Bach, M., Badura, E., Bähr, S., Balog, T., Balzer, M., Bao, E., Baranova, N., Barczyk, T., Bartoş, D., Bashir, S., Baszczyk, M., Batenkov, O., Baublis, V., Baznat, M., Becker, J., Becker, K. -H., Belogurov, S., Belyakov, D., Bendarouach, J., Berceanu, I., Bercuci, A., Berdnikov, A., Berdnikov, Y., Berendes, R., Berezin, G., Bergmann, C., Bertini, D., Bertini, O., Beşliu, C., Bezshyyko, O., Bhaduri, P. P., Bhasin, A., Bhati, A. K., Bhattacharjee, B., Bhattacharyya, A., Bhattacharyya, T. K., Biswas, S., Blank, T., Blau, D., Blinov, V., Blume, C., Bocharov, Yu., Book, J., Breitner, T., Brüning, U., Brzychczyk, J., Bubak, A., Büsching, H., Bus, T., Butuzov, V., Bychkov, A., Byszuk, A., Cai, Xu, Cãlin, M., Cao, Ping, Caragheorgheopol, G., Carević, I., Cătănescu, V., Chakrabarti, A., Chattopadhyay, S., Chaus, A., Chen, Hongfang, Chen, LuYao, Cheng, Jianping, Chepurnov, V., Cherif, H., Chernogorov, A., Ciobanu, M. I., Claus, G., Constantin, F., Csanád, M., D’Ascenzo, N., Das, Supriya, Das, Susovan, de Cuveland, J., Debnath, B., Dementiev, D., Deng, Wendi, Deng, Zhi, Deppe, H., Deppner, I., Derenovskaya, O., Deveaux, C. A., Deveaux, M., Dey, K., Dey, M., Dillenseger, P., Dobyrn, V., Doering, D., Dong, Sheng, Dorokhov, A., Dreschmann, M., Drozd, A., Dubey, A. K., Dubnichka, S., Dubnichkova, Z., Dürr, M., Dutka, L., Dželalija, M., Elsha, V. V., Emschermann, D., Engel, H., Eremin, V., Eşanu, T., Eschke, J., Eschweiler, D., Fan, Huanhuan, Fan, Xingming, Farooq, M., Fateev, O., Feng, Shengqin, Figuli, S. P. D., Filozova, I., Finogeev, D., Fischer, P., Flemming, H., Förtsch, J., Frankenfeld, U., Friese, V., Friske, E., Fröhlich, I., Frühauf, J., Gajda, J., Galatyuk, T., Gangopadhyay, G., García Chávez, C., Gebelein, J., Ghosh, P., Ghosh, S. K., Gläßel, S., Goffe, M., Golinka-Bezshyyko, L., Golovatyuk, V., Golovnya, S., Golovtsov, V., Golubeva, M., Golubkov, D., Gómez Ramírez, A., Gorbunov, S., Gorokhov, S., Gottschalk, D., Gryboś, P., Grzeszczuk, A., Guber, F., Gudima, K., Gumiński, M., Gupta, A., Gusakov, Yu., Han, Dong, Hartmann, H., He, Shue, Hehner, J., Heine, N., Herghelegiu, A., Herrmann, N., Heß, B., Heuser, J. M., Himmi, A., Höhne, C., Holzmann, R., Hu, Dongdong, Huang, Guangming, Huang, Xinjie, Hutter, D., Ierusalimov, A., Ilgenfritz, E. -M., Irfan, M., Ivanischev, D., Ivanov, M., Ivanov, P., Ivanov, Valery, Ivanov, Victor, Ivanov, Vladimir, Ivashkin, A., Jaaskelainen, K., Jahan, H., Jain, V., Jakovlev, V., Janson, T., Jiang, Di, Jipa, A., Kadenko, I., Kähler, P., Kämpfer, B., Kalinin, V., Kallunkathariyil, J., Kampert, K. -H., Kaptur, E., Karabowicz, R., Karavichev, O., Karavicheva, T., Karmanov, D., Karnaukhov, V., Karpechev, E., Kasiński, K., Kasprowicz, G., Kaur, M., Kazantsev, A., Kebschull, U., Kekelidze, G., Khan, M. M., Khan, S. A., Khanzadeev, A., Khasanov, F., Khvorostukhin, A., Kirakosyan, V., Kirejczyk, M., Kiryakov, A., Kiš, M., Kisel, I., Kisel, P., Kiselev, S., Kiss, T., Klaus, P., Kłeczek, R., Klein-Bösing, Ch., Kleipa, V., Klochkov, V., Kmon, P., Koch, K., Kochenda, L., Koczoń, P., Koenig, W., Kohn, M., Kolb, B. W., Kolosova, A., Komkov, B., Korolev, M., Korolko, I., Kotte, R., Kovalchuk, A., Kowalski, S., Koziel, M., Kozlov, G., Kozlov, V., Kramarenko, V., Kravtsov, P., Krebs, E., Kreidl, C., Kres, I., Kresan, D., Kretschmar, G., Krieger, M., Kryanev, A. V., Kryshen, E., Kuc, M., Kucewicz, W., Kucher, V., Kudin, L., Kugler, A., Kumar, Ajit, Kumar, Ashwini, Kumar, L., Kunkel, J., Kurepin, A., Kurepin, N., Kurilkin, A., Kurilkin, P., Kushpil, V., Kuznetsov, S., Kyva, V., Ladygin, V., Lara, C., Larionov, P., Laso García, A., Lavrik, E., Lazanu, I., Lebedev, A., Lebedev, S., Lebedeva, E., Lehnert, J., Lehrbach, J., Leifels, Y., Lemke, F., Li, Cheng, Li, Qiyan, Li, Xin, Li, Yuanjing, Lindenstruth, V., Linnik, B., Liu, Feng, Lobanov, I., Lobanova, E., Löchner, S., Loizeau, P. -A., Lone, S. A., Lucio Martínez, J. A., Luo, Xiaofeng, Lymanets, A., Lyu, Pengfei, Maevskaya, A., Mahajan, S., Mahapatra, D. P., Mahmoud, T., Maj, P., Majka, Z., Malakhov, A., Malankin, E., Malkevich, D., Malyatina, O., Malygina, H., Mandal, M. M., Mandal, S., Manko, V., Manz, S., Marin Garcia, A. M., Markert, J., Masciocchi, S., Matulewicz, T., Meder, L., Merkin, M., Mialkovski, V., Michel, J., Miftakhov, N., Mik, L., Mikhailov, K., Mikhaylov, V., Milanović, B., Militsija, V., Miskowiec, D., Momot, I., Morhardt, T., Morozov, S., Müller, W. F. J., Müntz, C., Mukherjee, S., Muñoz Castillo, C. E., Murin, Yu., Najman, R., Nandi, C., Nandy, E., Naumann, L., Nayak, T., Nedosekin, A., Negi, V. S., Niebur, W., Nikulin, V., Normanov, D., Oancea, A., Oh, Kunsu, Onishchuk, Yu., Ososkov, G., Otfinowski, P., Ovcharenko, E., Pal, S., Panasenko, I., Panda, N. R., Parzhitskiy, S., Patel, V., Pauly, C., Penschuck, M., Peshekhonov, D., Peshekhonov, V., Petráček, V., Petri, M., Petriş, M., Petrovici, A., Petrovici, M., Petrovskiy, A., Petukhov, O., Pfeifer, D., Piasecki, K., Pieper, J., Pietraszko, J., Płaneta, R., Plotnikov, V., Plujko, V., Pluta, J., Pop, A., Pospisil, V., Poźniak, K., Prakash, A., Prasad, S. K., Prokudin, M., Pshenichnov, I., Pugach, M., Pugatch, V., Querchfeld, S., Rabtsun, S., Radulescu, L., Raha, S., Rami, F., Raniwala, R., Raniwala, S., Raportirenko, A., Rautenberg, J., Rauza, J., Ray, R., Razin, S., Reichelt, P., Reinecke, S., Reinefeld, A., Reshetin, A., Ristea, C., Ristea, O., Rodriguez Rodriguez, A., Roether, F., Romaniuk, R., Rost, A., Rostchin, E., Rostovtseva, I., Roy, Amitava, Roy, Ankhi, Rożynek, J., Ryabov, Yu., Sadovsky, A., Sahoo, R., Sahu, P. K., Sahu, S. K., Saini, J., Samanta, S., Sambyal, S. S., Samsonov, V., Sánchez Rosado, J., Sander, O., Sarangi, S., Satława, T., Sau, S., Saveliev, V., Schatral, S., Schiaua, C., Schintke, F., Schmidt, C. J., Schmidt, H. R., Schmidt, K., Scholten, J., Schweda, K., Seck, F., Seddiki, S., Selyuzhenkov, I., Semennikov, A., Senger, A., Senger, P., Shabanov, A., Shabunov, A., Shao, Ming, Sheremetiev, A. D., Shi, Shusu, Shumeiko, N., Shumikhin, V., Sibiryak, I., Sikora, B., Simakov, A., Simon, C., Simons, C., Singaraju, R. N., Singh, A. K., Singh, B. K., Singh, C. P., Singhal, V., Singla, M., Sitzmann, P., Siwek-Wilczyńska, K., Škoda, L., Skwira-Chalot, I., Som, I., Song, Guofeng, Song, Jihye, Sosin, Z., Soyk, D., Staszel, P., Strikhanov, M., Strohauer, S., Stroth, J., Sturm, C., Sultanov, R., Sun, Yongjie, Svirida, D., Svoboda, O., Szabó, A., Szczygieł, R., Talukdar, R., Tang, Zebo, Tanha, M., Tarasiuk, J., Tarassenkova, O., Târzilă, M. -G., Teklishyn, M., Tischler, T., Tlustý, P., Tölyhi, T., Toia, A., Topil’skaya, N., Träger, M., Tripathy, S., Tsakov, I., Tsyupa, Yu., Turowiecki, A., Tuturas, N. G., Uhlig, F., Usenko, E., Valin, I., Varga, D., Vassiliev, I., Vasylyev, O., Verbitskaya, E., Verhoeven, W., Veshikov, A., Visinka, R., Viyogi, Y. P., Volkov, S., Volochniuk, A., Vorobiev, A., Voronin, Aleksey, Voronin, Alexander, Vovchenko, V., Vznuzdaev, M., Wang, Dong, Wang, Xi-Wei, Wang, Yaping, Wang, Yi, Weber, M., Wendisch, C., Wessels, J. P., Wiebusch, M., Wiechula, J., Wielanek, D., Wieloch, A., Wilms, A., Winckler, N., Winter, M., Wiśniewski, K., Wolf, Gy., Won, Sanguk, Wu, Ke-Jun, Wüstenfeld, J., Xiang, Changzhou, Xu, Nu, Yang, Junfeng, Yang, Rongxing, Yin, Zhongbao, Yoo, In-Kwon, Yuldashev, B., Yushmanov, I., Zabołotny, W., Zaitsev, Yu., Zamiatin, N. I., Zanevsky, Yu., Zhalov, M., Zhang, Yifei, Zhang, Yu, Zhao, Lei, Zheng, Jiajun, Zheng, Sheng, Zhou, Daicui, Zhou, Jing, Zhu, Xianglei, Zinchenko, A., Zipper, W., Żoładź, M., Zrelov, P., Zryuev, V., Zumbruch, P., and Zyzak, M.

Published
2017
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29. Stetigförderer

Author

Bruns, R., Günthner, W., ten Hompel, M., Katterfeld, A., Kessler, F., Krause, F., Kunze, G., Marquardt, H.-G., Overmeyer, L., Poppy, W., Schmidt, T., Scholten, J., Wagner, G., Wehking, K.-H., Grote, Karl-Heinrich, editor, and Feldhusen, Jörg, editor

Published
2011
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30. Grundlagen

Author

Wagner, G., Marquardt, H.-G., Scholten, J., Wehking, K.-H., Schmidt, T., Grote, Karl-Heinrich, editor, and Feldhusen, Jörg, editor

Published
2011
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33. Fördertechnik

Author

Bruns, R., Günthner, W., ten Hompel, M., Kessler, F., Krause, F., Kunze, G., Marquardt, H. -G., Poppy, W., Scholten, J., Severin, D., Wagner, G., Grote, Karl-Heinrich, editor, and Feldhusen, Jörg, editor

Published
2007
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37. Radon (222Rn) as tracer for submarine groundwater discharge investigation—limitations of the approach at shallow wind-exposed coastal settings

Author

Schubert, Michael, Scholten, J., Kreuzburg, M., Petermann, E., de Paiva, M.L., Köhler, D., Liebetrau, V., Rapaglia, J., Schlüter, M., Schubert, Michael, Scholten, J., Kreuzburg, M., Petermann, E., de Paiva, M.L., Köhler, D., Liebetrau, V., Rapaglia, J., and Schlüter, M.

Abstract

Mapping radon (222Rn) distribution patterns in the coastal sea is a widely applied method for localizing and quantifying submarine groundwater discharge (SGD). While the literature reports a wide range of successful case studies, methodical problems that might occur in shallow wind-exposed coastal settings are generally neglected. This paper evaluates causes and effects that resulted in a failure of the radon approach at a distinct shallow wind-exposed location in the Baltic Sea. Based on a simple radon mass balance model, we discuss the effect of both wind speed and wind direction as causal for this failure. We show that at coastal settings, which are dominated by gentle submarine slopes and shallow waters, both parameters have severe impact on coastal radon distribution patterns, thus impeding their use for SGD investigation. In such cases, the radon approach needs necessarily to allow for the impact of wind speed and wind direction not only during but also prior to the field campaign.

Published
2022

40. Materials research under ITER-like divertor conditions at FOM Rijnhuizen

Author

Wright, G.M., Westerhout, J., Al, R.S., Alves, E., Alves, L.C., Barradas, N.P., van den Berg, M.A., Borodin, D., Brezinsek, S., Brons, S., van Eck, H.J.N., de Groot, B., Kleyn, A.W., Koppers, W.R., Kruijt, O.G., Linke, J., Lopes Cardozo, N.J., Mayer, M., van der Meiden, H.J., Prins, P.R., van Rooij, G.J., Scholten, J., Shumack, A.E., Smeets, P.H.M., De Temmerman, G., Vijvers, W.A.J., and Rapp, J.

Published
2011
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42. New linear plasma devices in the trilateral euregio cluster for an integrated approach to plasma surface interactions in fusion reactors

Author

Unterberg, B., Jaspers, R., Koch, R., Massaut, V., Rapp, J., Reiter, D., Kraus, S., Kreter, A., Philipps, V., Reimer, H., Samm, U., Scheibl, L., Schweer, B., Schuurmans, J., Uytdenhouwen, I., Al, R., van den Berg, M.A., Brons, S., van Eck, H.J.N., Goedheer, W.J., Graswinckel, M.F., van der Grift, T., Kleyn, A., Koppers, W.R., Kruyt, O., Lof, A., van der Meiden, H.J., Melissen, W., van de Pol, M., van Rooij, G.J., Smeets, P., Scholten, J., Schram, D.C., De Temmerman, G., Vijvers, W., Emmichoven, P.A. Zeijlmans van, and Zielinski, J.J.

Published
2011
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48. Construction of the plasma-wall experiment Magnum-PSI

Author

Rapp, J., Koppers, W.R., van Eck, H.J.N., van Rooij, G.J., Goedheer, W.J., de Groot, B., Al, R., Graswinckel, M.F., van den Berg, M.A., Kruyt, O., Smeets, P., van der Meiden, H.J., Vijvers, W., Scholten, J., van de Pol, M., Brons, S., Melissen, W., van der Grift, T., Koch, R., Schweer, B., Samm, U., Philipps, V., Engeln, R.A.H., Schram, D.C., Lopes Cardozo, N.J., and Kleyn, A.W.

Published
2010
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