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9 results on '"Schoettler, Friederike I."'

7. The rare case of double valve surgery in a patient with factor VII deficiency.

Author

Schoettler, Friederike I., Fatehi Hassanabad, Ali, Chiu, Michael H., Ferland, Andre, and Adams, Corey

Subjects
*ATRIAL fibrillation diagnosis, *HEART valve surgery, *PNEUMONIA treatment, *TRICUSPID valve surgery, *MITRAL valve surgery, *RED blood cell transfusion, *ANTICOAGULANTS, *SUBSTANCE abuse, *MEDICAL history taking, *BLOOD coagulation disorders, *BLOOD testing, *RARE diseases, *HEPARIN, *RESPIRATORY insufficiency, *HEART failure, *DECISION making in clinical medicine, *AMIODARONE, *SURGICAL complications, *MITRAL valve insufficiency, *VENTRICULAR dysfunction, *GENETIC disorders, *ATRIAL fibrillation, *INTERNATIONAL normalized ratio, *SURGICAL hemostasis, *NOSOCOMIAL infections, *ARTIFICIAL respiration, *CARDIAC surgery, *HEMORRHAGE, *AORTIC valve insufficiency, *ECHOCARDIOGRAPHY, *NOSEBLEED
Abstract

Performing cardiac surgery on patients with bleeding diatheses poses significant challenges since these patients are at an increased risk for complications secondary to excessive bleeding. Despite its rarity, patients with factor VII (FVII) deficiency may require invasive procedures such as cardiac surgery. However, we lack guidelines on their pre-, peri-, and post-operative management. As FVII deficiency is rare, it seems unlikely to design and learn from large clinical studies. Instead, we need to base our clinical decision-making on single reported cases and registry data. Herein, we present the rare case of a patient with FVII deficiency who underwent double valve surgery. Pre-operatively, activated recombinant FVII (rFVIIa) was administered to reduce the risk of bleeding. Nevertheless, the patient experienced major bleeding. This case highlights the significance of FVII deficiency in patients undergoing cardiac surgery and emphasizes the importance of adequate and appropriate transfusion of blood products for these patients. [ABSTRACT FROM AUTHOR]

Published
2024
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