463 results on '"Schneider, Bernard L."'
Search Results
2. Stable isotope labeling and ultra-high-resolution NanoSIMS imaging reveal alpha-synuclein-induced changes in neuronal metabolism in vivo
3. Central and peripheral delivered AAV9-SMN are both efficient but target different pathomechanisms in a mouse model of spinal muscular atrophy
4. Mitofusin-2 in the Nucleus Accumbens Regulates Anxiety and Depression-like Behaviors Through Mitochondrial and Neuronal Actions
5. Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice
6. SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease
7. Interactions of VMAT2 with CDCrel-1 and Parkin in Methamphetamine Neurotoxicity.
8. Central anorexigenic actions of bile acids are mediated by TGR5
9. Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells
10. Altered interplay between endoplasmic reticulum and mitochondria in Charcot–Marie–Tooth type 2A neuropathy
11. The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging
12. Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development
13. Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss
14. Parkin regulates drug-taking behavior in rat model of methamphetamine use disorder
15. Lentiviral Vector Delivery of Parkin Prevents Dopaminergic Degeneration in an α-Synuclein Rat Model of Parkinson's Disease
16. Long term peripheral AAV9-SMN gene therapy promotes survival in a mouse model of spinal muscular atrophy
17. Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL
18. Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology
19. Nano-imaging trace elements at organelle levels in substantia nigra overexpressing α-synuclein to model Parkinson’s disease
20. Cortico–reticulo–spinal circuit reorganization enables functional recovery after severe spinal cord contusion
21. Regulation of Memory Formation by the Transcription Factor XBP1
22. In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons
23. Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
24. Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity
25. Stable isotope labeling and ultra-high-resolution NanoSIMS imaging reveal alpha-synuclein-induced changes in neuronal metabolism in vivo
26. Long term peripheral AAV9-SMN gene therapy promotes survival in a mouse model of spinal muscular atrophy.
27. Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease
28. Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology
29. α-Synuclein-induced dopaminergic neurodegeneration in a rat model of Parkinson's disease occurs independent of ATP13A2 (PARK9)
30. Scalable Production and Purification of Adeno-Associated Viral Vectors (AAV)
31. Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
32. Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation
33. A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells
34. Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity
35. Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model
36. Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo
37. Recovery of walking after paralysis by regenerating characterized neurons to their natural target region.
38. Selective Vulnerability of Neuronal Subtypes in ALS: A Fertile Ground for the Identification of Therapeutic Targets
39. Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?
40. Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons
41. Neuroprotection by Gene Therapy Targeting Mutant SOD1 in Individual Pools of Motor Neurons Does not Translate Into Therapeutic Benefit in fALS Mice
42. Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth
43. Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons
44. Lentiviral Vectors for the Engineering of Implantable Cells Secreting Recombinant Antibodies
45. A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies
46. Astrocyte‐targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast‐fatigable motor units in a mouse model of amyotrophic lateral sclerosis
47. Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons
48. Chondroitinase gene therapy improves upper limb function following cervical contusion injury
49. Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease
50. Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity.
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