434 results on '"Schneider, Bernard L."'
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2. Central and peripheral delivered AAV9-SMN are both efficient but target different pathomechanisms in a mouse model of spinal muscular atrophy
3. SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease
4. Central anorexigenic actions of bile acids are mediated by TGR5
5. Long term peripheral AAV9-SMN gene therapy promotes survival in a mouse model of spinal muscular atrophy
6. Altered interplay between endoplasmic reticulum and mitochondria in Charcot–Marie–Tooth type 2A neuropathy
7. Parkin regulates drug-taking behavior in rat model of methamphetamine use disorder
8. Long term peripheral AAV9-SMN gene therapy promotes survival in a mouse model of spinal muscular atrophy.
9. Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development
10. Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss
11. Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology
12. Nano-imaging trace elements at organelle levels in substantia nigra overexpressing α-synuclein to model Parkinson’s disease
13. Lentiviral Vector Delivery of Parkin Prevents Dopaminergic Degeneration in an α-Synuclein Rat Model of Parkinson's Disease
14. Cortico–reticulo–spinal circuit reorganization enables functional recovery after severe spinal cord contusion
15. Stable isotope labeling and ultra-high-resolution NanoSIMS imaging reveal alpha-synuclein-induced changes in neuronal metabolism in vivo
16. In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons
17. Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
18. Scalable Production and Purification of Adeno-Associated Viral Vectors (AAV)
19. Recovery of walking after paralysis by regenerating characterized neurons to their natural target region.
20. Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity
21. Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation
22. A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells
23. Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
24. Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinsonʼs disease and increases the neurotoxicity of DOPAL
25. Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?
26. Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model
27. Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo
28. Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons
29. Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity.
30. Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth
31. Selective Vulnerability of Neuronal Subtypes in ALS: A Fertile Ground for the Identification of Therapeutic Targets
32. Lentiviral Vectors for the Engineering of Implantable Cells Secreting Recombinant Antibodies
33. Astrocyte‐targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast‐fatigable motor units in a mouse model of amyotrophic lateral sclerosis
34. The exercise-induced long noncoding RNA CYTOR promotes fast-twitch myogenesis in aging
35. Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons
36. A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies
37. Central and peripheral delivery of AAV9-SMN target different pathomechanisms in a mouse model of spinal muscular atrophy
38. Chondroitinase gene therapy improves upper limb function following cervical contusion injury
39. Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology
40. The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain
41. Behaviour-dependent recruitment of long-range projection neurons in somatosensory cortex
42. Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain
43. Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation
44. Mitofusin-2 in the Nucleus Accumbens Regulates Anxiety and Depression-like Behaviors Through Mitochondrial and Neuronal Actions
45. CSPα reduces aggregates and rescues striatal dopamine release in α-synuclein transgenic mice
46. The exercise-induced long noncoding RNA CYTOR promotes fast-twitch myogenesis in aging
47. A Parkinsonʼs disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity
48. Parkinsonʼs disease-linked mutations in VPS35 induce dopaminergic neurodegeneration
49. FOXO3 determines the accumulation of α-synuclein and controls the fate of dopaminergic neurons in the substantia nigra
50. The Links between ALS and NF-κB
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