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5. Georg Schmorl prize of the German spine society (DWG) 2022: current treatment for inpatients with osteoporotic thoracolumbar fractures—results of the EOFTT study

Author

Ullrich, Bernhard W., Schenk, Philipp, Scheyerer, Max J., Bäumlein, Martin, Katscher, Sebastian, Schnake, Klaus J., Zimmermann, Volker, Schwarz, Falko, Schmeiser, Gregor, Scherer, Michael, Müller, Michael, Sprengel, Kai, Osterhoff, Georg, Liepold, Katja, Schramm, Simon, Baron, Christopher, Siekmann, Holger, Franck, Alexander, Isik, N., Klauke, Friederike, and Spiegl, Ulrich J. A.

Published
2023
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8. The Diagnostic Process of Spinal Post-traumatic Deformity: An Expert Survey of 7 Cases, Consensus on Clinical Relevance Does Exist

Author

De Gendt, Erin E.A., Benneker, Lorin M., Joaquim, Andrei F., El-Sharkawi, Mohammad, Dhakal, Gaurav R., Kandziora, Frank, Tee, Jin, Bransford, Richard J., Vialle, Emiliano N., Vaccaro, Alex R., Popescu, Eugen C., Kanna, Rishi M., Polly, David W., Schnake, Klaus J., Berjano, Pedro, Ryabykh, Sergey, Neva, Marko, Lamartina, Claudio, Rothenfluh, Dominique A., Lewis, Stephan J., Muijs, Sander P.J., and Oner, F. Cumhur

Published
2023
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15. Validation of the AO Spine CROST (Clinician Reported Outcome Spine Trauma) in the clinical setting

Author

Zorgeenheid Orthopaedie Medisch, Orthopaedie Opleiding, MS Orthopaedie Algemeen, Other research (not in main researchprogram), Regenerative Medicine and Stem Cells, Sadiqi, Said, de Gendt, Erin E.A., Muijs, Sander P.J., Post, Marcel W.M., Benneker, Lorin M., Holas, Martin, Tee, Jin W., Albers, Christoph E., Häckel, Sonja, Svac, Juraj, Bransford, Richard J., El-Sharkawi, Mohammad M., Kandziora, Frank, Rajasekaran, Shanmuganathan, Schnake, Klaus J., Vaccaro, Alexander R., Oner, F. Cumhur, Zorgeenheid Orthopaedie Medisch, Orthopaedie Opleiding, MS Orthopaedie Algemeen, Other research (not in main researchprogram), Regenerative Medicine and Stem Cells, Sadiqi, Said, de Gendt, Erin E.A., Muijs, Sander P.J., Post, Marcel W.M., Benneker, Lorin M., Holas, Martin, Tee, Jin W., Albers, Christoph E., Häckel, Sonja, Svac, Juraj, Bransford, Richard J., El-Sharkawi, Mohammad M., Kandziora, Frank, Rajasekaran, Shanmuganathan, Schnake, Klaus J., Vaccaro, Alexander R., and Oner, F. Cumhur

Published
2024

16. OF-Pelvis classification of osteoporotic sacral and pelvic ring fractures

Author

Ullrich, Bernhard W., Schnake, Klaus J., Spiegl, Ulrich J. A., Schenk, Philipp, Mendel, Thomas, Behr, Lars, Bula, Philipp, Flücht, Laura B., Franck, Alexander, Gercek, Erol, Grüninger, Sebastian, Hartung, Philipp, Jacobs, Cornelius, Katscher, Sebastian, Klauke, Friederike, Liepold, Katja, Müller, Christian W., Müller, Michael, Osterhoff, Georg, Partenheimer, Axel, Piltz, Stefan, Riehle, Marion, Sauer, Daniel, Scheyerer, Max Joseph, Schleicher, Philipp, Schmeiser, Gregor, Schmidt, René, Scholz, Matti, Siekmann, Holger, Sprengel, Kai, Stoevesandt, Dietrich, Verheyden, Akhil, and Zimmermann, Volker

Published
2021
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17. Streamlining the Journey of Research Into Clinical Practice: Making Your Patients and Practice Flourish Optimizing Management and Minimizing Risk of Osteoporotic Vertebral Fractures – Perspectives of the AO Spine KF Trauma and Infection Group Key Opinion Leaders

Author

Joaquim, Andrei F., Bigdon, Sebastian F., Bransford, Richard, Chhabra, Harvinder Singh, Yurac, Ratko, Kumar, Vishal, El-Sharkawi, Mohammad, Benneker, Lorin M., Karamian, Brian A., Canseco, Jose A., Scherer, Julian, Hassan, Ahmed Abdelazim, Schroeder, Gregory D., Öner, Cumhur F., Rajasekaran, Shanmuganathan, Vialle, Emiliano, Kanna, Rishi M., Vaccaro, Alexander R., Tee, Jin, Camino-Willhuber, Gaston, Fisher, Charles G., Dvorak, Marcel F., and Schnake, Klaus J.

Abstract

Study Design Literature review with clinical recommendations.Objective To highlight important studies about osteoporotic spinal fractures (OF) that may be integrated into clinical practice based on the assessment of the AO Spine KF Trauma and Infection group key opinion leaders.Methods 4 important studies about OF that may affect current clinical practice of spinal surgeons were selected and reviewed with the aim of providing clinical recommendations to streamline the journey of research into clinical practice. Recommendations were graded as strong or conditional following the GRADE methodology.Results 4 studies were selected. Article 1: a validation of the Osteoporotic Fracture (OF)-score to treat OF fractures. Conditionalrecommendation to incorporate the OF score in the management of fractures to improve clinical results. Article 2: a randomized multicenter study comparing romosozumab/alendronate vs alendronate to decrease the incidence of new vertebral fractures. Strongrecommendation that the group receiving romosozumab/alendronate had a decreased risk of new OF when compared with the alendronate only group only. Article 3: a systematic literature review of spinal orthoses in the management of. Conditionalrecommendation to prescribe a spinal orthosis to decrease pain and improve quality of life. Article 4: post-traumatic deformity after OF. A conditionalrecommendation that middle column injury and pre-injury use of steroids may lead to high risk of post-traumatic deformity after OF.Conclusions Management of patients with OF is still complex and challenging. This review provides some recommendations that may help surgeons to better manage these patients and improve their clinical practice.

Published
2024
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19. Using Equipoise to Determine the Radiographic Characteristics Leading to Agreement on Best Treatment for Thoracolumbar Burst Fractures Without Neurologic Deficits

Author

Dandurand, Charlotte, primary, Dvorak, Marcel F., additional, Hazenbiller, Olesja, additional, Bransford, Richard J., additional, Schnake, Klaus J., additional, Vaccaro, Alexander R., additional, Benneker, Lorin M., additional, Vialle, Emiliano, additional, Schroeder, Gregory D., additional, Rajasekaran, Shanmuganathan, additional, El-Skarkawi, Mohammad, additional, Kanna, Rishi M., additional, Aly, Mohamed M., additional, Holas, Martin, additional, Canseco, Jose A., additional, Muijs, Sander, additional, Popescu, Eugen C., additional, Tee, Jin Wee, additional, Camino-Willhuber, Gaston, additional, Joaquim, Andrei Fernandes, additional, Keynan, Ory, additional, Chhabra, Harvinder Singh, additional, Bigdon, Sebastian, additional, Spiegel, Ulrich, additional, and Öner, Cumhur F., additional

Published
2024
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20. Does Erector Spinae Plane Block Decrease Analgesia Requirements After Minimal-Invasive Posterior Transpedicular Stabilization in Patients With Vertebral Body Fracture? A Prospective, Randomized, Double-Blind Controlled Study.

Author

Holas, Martin, Hlásny, Jakub, Gajdoš, Radomír, Venglarčík, Michal, Šimko, Peter, Schnake, Klaus J., Merjavy, Peter, Pučan, Tomáš, Šváč, Juraj, Nagypál, Robert, Hríň, Tomáš, Botka, Michal, Nosál´, Slavomír, and Wimmerová, Soňa

Subjects
ERECTOR spinae muscles, VERTEBRAL fractures, PARAVERTEBRAL anesthesia, VERTEBROPLASTY, MINIMALLY invasive procedures, ANALGESIA, VISUAL analog scale
Abstract

Study design: Prospective randomized placebo controlled double blind trial. Objective: To examine the effect of ESP block after minimally invasive posterior stabilization for vertebral fractures on opioid consumption, pain, blood loss, disability level, and wound healing complications. Methodology: Patients indicated for minimal invasive posterior stabilisation were included to the study. Our primary outcome was the opioid consumption and Visual Analogue Scale (VAS) measured during the first 48 hours. Secondary outcomes used to measure the short-term outcome included Oswestry Disability Index (ODI) and Patient Reported Outcome Spine Trauma (PROST). Results: In total, 60 patients were included with a 93.3% follow-up. Average morphine consumption during the PACU (Post Anaesthesia Care Unit) period was 5.357 mg in ESP group and 8.607 mg in placebo group (P =.004). Average VAS during first 24 hour was 3.944 in ESP group and 5.193 in placebo group (P =.046). Blood loss was 14.8 g per screw in ESP group and 15.4 g in placebo group (P =.387). The day2 PROST value was 33.9 in ESP group and 28.8 in placebo group (P =.008) and after 4 weeks 55.2 in ESP group and 49.9 in placebo group (P =.036). No significant differences in ODI were detected. Conclusion: The use of ESP block in minimally invasive spinal surgery for posterior fracture stabilization leads to a significant reduction of opioid consumption during PACU stay by 37.7%. Reduction of opioid consumption was accompanied with lower pain (VAS). We found positive effect of the ESP block on short term outcome scores, but no effect on perioperative blood loss and wound healing. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Validation of the AO Spine Sacral Classification System: Reliability Among Surgeons Worldwide

Author

Schroeder, Gregory D., Karamian, Brian A., Canseco, Jose A., Vialle, Luiz R., Kandziora, Frank, Benneker, Lorin M., Rajasekaran, Shanmuganathan, Holstein, Jörg H., Schnake, Klaus J., Kurd, Mark F., Dvorak, Marcel F., Vialle, Emiliano N., Joaquim, Andrei F., Kanna, Rishi M., Fehlings, Michael, Wilson, Jefferson R., Chapman, Jens R., Krieg, James C., Kleweno, Conor P., Firoozabadi, Reza, Öner, F. Cumhur, Kepler, Christopher K., and Vaccaro, Alexander R.

Published
2021
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23. Establishing the Injury Severity of Subaxial Cervical Spine Trauma: Validating the Hierarchical Nature of the AO Spine Subaxial Cervical Spine Injury Classification System

Author

Schroeder, Gregory D., Canseco, Jose A., Patel, Parthik D., Divi, Srikanth N., Karamian, Brian A., Kandziora, Frank, Vialle, Emiliano N., Oner, F. Cumhur, Schnake, Klaus J., Dvorak, Marcel F., Chapman, Jens R., Benneker, Lorin M., Rajasekaran, Shanmuganathan, Kepler, Christopher K., and Vaccaro, Alexander R.

Published
2020
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27. Description and Reliability of the AOSpine Sacral Classification System

Author

Vaccaro, Alexander R., Schroeder, Gregory D., Divi, Srikanth N., Kepler, Christopher K., Kleweno, Conor P., Krieg, James C., Wilson, Jefferson R., Holstein, Jörg H., Kurd, Mark F., Firoozabadi, Reza, Vialle, Luiz R., Oner, F. Cumhur, Kandziora, Frank, Chapman, Jens R., Schnake, Klaus J., Benneker, Lorin M., Dvorak, Marcel F., Rajasekaran, Shanmuganathan, Vialle, Emiliano N., Joaquim, Andrei F., El-Sharkawi, Mohammad Mostafa, Dhakal, Gaurav R., Popescu, Eugen C., Kanna, Rishi M., Muijs, S.P.J., Tee, Jin W., and Bellabarba, Carlo

Published
2020
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29. Spinal Post-traumatic Deformity: An International Expert Survey Among AO Spine Knowledge Forum Members

Author

Orthopaedie Opleiding, MS Orthopaedie Algemeen, Other research (not in main researchprogram), Regenerative Medicine and Stem Cells, De Gendt, Erin E A, Schroeder, Greg D, Joaquim, Andrei, Tee, Jin, Kanna, Rishi M, Kandziora, Frank, Dhakal, Gaurav R, Vialle, Emiliano N, El-Sharkawi, Mohammad, Schnake, Klaus J, Rajasekaran, Shanmuganathan, Vaccaro, Alex R, Muijs, Sander P J, Benneker, Lorin M, Oner, F Cumhur, Orthopaedie Opleiding, MS Orthopaedie Algemeen, Other research (not in main researchprogram), Regenerative Medicine and Stem Cells, De Gendt, Erin E A, Schroeder, Greg D, Joaquim, Andrei, Tee, Jin, Kanna, Rishi M, Kandziora, Frank, Dhakal, Gaurav R, Vialle, Emiliano N, El-Sharkawi, Mohammad, Schnake, Klaus J, Rajasekaran, Shanmuganathan, Vaccaro, Alex R, Muijs, Sander P J, Benneker, Lorin M, and Oner, F Cumhur

Published
2023

30. Georg Schmorl prize of the German spine society (DWG) 2022: current treatment for inpatients with osteoporotic thoracolumbar fractures-results of the EOFTT study

Author

Ullrich, Bernhard W; https://orcid.org/0000-0001-8748-1190, Schenk, Philipp, Scheyerer, Max J, Bäumlein, Martin, Katscher, Sebastian, Schnake, Klaus J, Zimmermann, Volker, Schwarz, Falko, Schmeiser, Gregor, Scherer, Michael, Müller, Michael, Sprengel, Kai, Osterhoff, Georg, Liepold, Katja, Schramm, Simon, Baron, Christopher, Siekmann, Holger, Franck, Alexander, Isik, N, Klauke, Friederike, Spiegl, Ulrich J A, Ullrich, Bernhard W; https://orcid.org/0000-0001-8748-1190, Schenk, Philipp, Scheyerer, Max J, Bäumlein, Martin, Katscher, Sebastian, Schnake, Klaus J, Zimmermann, Volker, Schwarz, Falko, Schmeiser, Gregor, Scherer, Michael, Müller, Michael, Sprengel, Kai, Osterhoff, Georg, Liepold, Katja, Schramm, Simon, Baron, Christopher, Siekmann, Holger, Franck, Alexander, Isik, N, Klauke, Friederike, and Spiegl, Ulrich J A

Abstract

AIM Osteoporotic thoracolumbar fractures are of increasing importance. To identify the optimal treatment strategy this multicentre prospective cohort study was performed. PURPOSE Patients suffering from osteoporotic thoracolumbar fractures were included. Excluded were tumour diseases, infections and limb fractures. Age, sex, trauma mechanism, OF classification, OF-score, treatment strategy, pain condition and mobilization were analysed. METHODS A total of 518 patients' aged 75 ± 10 (41-97) years were included in 17 centre. A total of 174 patients were treated conservatively, and 344 were treated surgically, of whom 310 (90%) received minimally invasive treatment. An increase in the OF classification was associated with an increase in both the likelihood of surgery and the surgical invasiveness. RESULTS Five (3%) complications occurred during conservative treatment, and 46 (13%) occurred in the surgically treated patients. 4 surgical site infections and 2 mechanical failures requested revision surgery. At discharge pain improved significantly from a visual analogue scale score of 7.7 (surgical) and 6.0 (conservative) to a score of 4 in both groups (p < 0.001). Over the course of treatment, mobility improved significantly (p = 0.001), with a significantly stronger (p = 0.007) improvement in the surgically treated patients. CONCLUSION Fracture severity according to the OF classification is significantly correlated with higher surgery rates and higher invasiveness of surgery. The most commonly used surgical strategy was minimally invasive short-segmental hybrid stabilization followed by kyphoplasty/vertebroplasty. Despite the worse clinical conditions of the surgically treated patients both conservative and surgical treatment led to an improved pain situation and mobility during the inpatient stay to nearly the same level for both treatments.

Published
2023

32. Georg Schmorl prize of the German spine society (DWG) 2022: current treatment for inpatients with osteoporotic thoracolumbar fractures-results of the EOFTT study

Author

Ullrich, Bernhard W, Schenk, Philipp, Scheyerer, Max J, Bäumlein, Martin, Katscher, Sebastian, Schnake, Klaus J, Zimmermann, Volker, Schwarz, Falko, Schmeiser, Gregor, Scherer, Michael, Müller, Michael, Sprengel, Kai, Osterhoff, Georg, Liepold, Katja, Schramm, Simon, Baron, Christopher, Siekmann, Holger, Franck, Alexander, Isik, N, Klauke, Friederike, Spiegl, Ulrich J A, University of Zurich, and Ullrich, Bernhard W

Subjects
10021 Department of Trauma Surgery, 2732 Orthopedics and Sports Medicine, 610 Medicine & health, 2746 Surgery
Abstract

Osteoporotic thoracolumbar fractures are of increasing importance. To identify the optimal treatment strategy this multicentre prospective cohort study was performed.Patients suffering from osteoporotic thoracolumbar fractures were included. Excluded were tumour diseases, infections and limb fractures. Age, sex, trauma mechanism, OF classification, OF-score, treatment strategy, pain condition and mobilization were analysed.A total of 518 patients' aged 75 ± 10 (41-97) years were included in 17 centre. A total of 174 patients were treated conservatively, and 344 were treated surgically, of whom 310 (90%) received minimally invasive treatment. An increase in the OF classification was associated with an increase in both the likelihood of surgery and the surgical invasiveness.Five (3%) complications occurred during conservative treatment, and 46 (13%) occurred in the surgically treated patients. 4 surgical site infections and 2 mechanical failures requested revision surgery. At discharge pain improved significantly from a visual analogue scale score of 7.7 (surgical) and 6.0 (conservative) to a score of 4 in both groups (p 0.001). Over the course of treatment, mobility improved significantly (p = 0.001), with a significantly stronger (p = 0.007) improvement in the surgically treated patients.Fracture severity according to the OF classification is significantly correlated with higher surgery rates and higher invasiveness of surgery. The most commonly used surgical strategy was minimally invasive short-segmental hybrid stabilization followed by kyphoplasty/vertebroplasty. Despite the worse clinical conditions of the surgically treated patients both conservative and surgical treatment led to an improved pain situation and mobility during the inpatient stay to nearly the same level for both treatments.

Published
2023

36. Impact of anxiety during hospitalization on the clinical outcome of patients with osteoporotic thoracolumbar vertebral fracture: a prospective multicentric study

Author

Schwarz, Falko, primary, Klee, Emma, additional, Schenk, Philipp, additional, Katscher, Sebastian, additional, Schnake, Klaus J., additional, Bäumlein, Martin, additional, Schmeiser, Gregor, additional, Scherer, Michael A., additional, Müller, Michael, additional, Sprengel, Kai, additional, Spiegl, Ulrich, additional, Osterhoff, Georg, additional, Schramm, Simon, additional, Siekmann, Holger, additional, Franck, Alexander, additional, Scheyerer, Max J., additional, and Ullrich, Bernhard W., additional

Published
2023
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37. Does Erector Spinae Plane Block Decrease Analgesia Requirements After Minimal-Invasive Posterior Transpedicular Stabilization in Patients With Vertebral Body Fracture? A Prospective, Randomized, Double-Blind Controlled Study

Author

Holas, Martin, primary, Hlásny, Jakub, additional, Gajdoš, Radomír, additional, Venglarčík, Michal, additional, Šimko, Peter, additional, Schnake, Klaus J., additional, Merjavy, Peter, additional, Pučan, Tomáš, additional, Šváč, Juraj, additional, Nagypál, Robert, additional, Hríň, Tomáš, additional, Botka, Michal, additional, Nosál´, Slavomír, additional, and Wimmerová, Soňa, additional

Published
2023
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38. Evolution of the AO Spine Sacral and Pelvic Classification System: a systematic review

Author

Kweh, Barry Ting Sheen, primary, Tee, Jin W., additional, Oner, F. Cumhur, additional, Schnake, Klaus J., additional, Vialle, Emiliano N., additional, Kanziora, Frank, additional, Rajasekaran, Shanmuganathan, additional, Dvorak, Marcel, additional, Chapman, Jens R., additional, Benneker, Lorin M., additional, Schroeder, Gregory, additional, and Vaccaro, Alexander R., additional

Published
2022
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39. What Factors Influence Surgeons in Decision-Making in Thoracolumbar Burst Fractures? A Survey-Based Investigation of a Panel of Spine Surgery Experts

Author

Dvorak, Marcel F., Öner, Cumhur F., Schnake, Klaus, Dandurand, Charlotte, Muijs, Sander, Schnake, Klaus J., Dvorak, Marcel F., Öner, Cumhur F., Dandurand, Charlotte, Muijs, Sander, and Bigdon, Sebastian F.

Abstract

Study Design Cross-sectional survey study.Objective To investigate factors affecting decision-making in thoracolumbar burst-fractures without neurologic deficit.Methods A 40-question survey addressing expert-related, economic, and radiological factors was distributed to 30 international trauma experts. Descriptive statistics were used to assess the impact of these factors on operative or non-operative management preferences.Results Out of 30 experts, 27 completed the survey. The majority of respondents worked at level 1 trauma centers (81.5%) within university settings (77.8%). They were primarily orthopedic surgeons (66.7%) and had over 10 years of experience (70.4%). About 81% found distinguishing between A3 and A4 fractures relevant for decision-making. Most experts (59%) treated A3 fractures non-surgically, while only 30% treated A4 fractures conservatively. Compensation systems did not influence treatment recommendations, and hospital measures promoting surgeries did not significantly affect distribution. Radiological factors, such as local kyphosis (25/27), fracture comminution (23/27), overall sagittal balance (21/27), and spinal canal narrowing (20/27), influenced decisions.Conclusion Incomplete burst fractures (A3) are predominantly treated non-surgically, while complete burst fractures (A4) are primarily treated surgically. Compensation, third-party incentives, and outpatient care did not significantly impact decision-making. Radiological factors beyond the AO Spine thoracolumbar classification system seem to be essential and warrant further evaluation.

Published
2024
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40. Using Equipoise to Determine the Radiographic Characteristics Leading to Agreement on Best Treatment for Thoracolumbar Burst Fractures Without Neurologic Deficits

Author

Dvorak, Marcel F., Öner, Cumhur F., Schnake, Klaus, Dandurand, Charlotte, Muijs, Sander, Dandurand, Charlotte, Dvorak, Marcel F., Hazenbiller, Olesja, Bransford, Richard J., Schnake, Klaus J., Vaccaro, Alexander R., Benneker, Lorin M., Vialle, Emiliano, Schroeder, Gregory D., Rajasekaran, Shanmuganathan, El-Skarkawi, Mohammad, Kanna, Rishi M., Aly, Mohamed M., Holas, Martin, Canseco, Jose A., Muijs, Sander, Popescu, Eugen C., Tee, Jin Wee, Camino-Willhuber, Gaston, Joaquim, Andrei Fernandes, Keynan, Ory, Chhabra, Harvinder Singh, Bigdon, Sebastian, Spiegel, Ulrich, and Öner, Cumhur F.

Abstract

Study Design Retrospective analysis of prospectively collected data.Objectives Our goal was to assess radiographic characteristics associated with agreement and disagreement in treatment recommendation in thoracolumbar (TL) burst fractures.Methods A panel of 22 AO Spine Knowledge Forum Trauma experts reviewed 183 cases and were asked to: (1) classify the fracture; (2) assess degree of certainty of PLC disruption; (3) assess degree of comminution; and (4) make a treatment recommendation. Equipoise threshold used was 77% (77:23 distribution of uncertainty or 17 vs 5 experts). Two groups were created: consensus vs equipoise.Results Of the 183 cases reviewed, the experts reached full consensus in only 8 cases (4.4%). Eighty-one cases (44.3%) were included in the agreement group and 102 cases (55.7%) in the equipoise group. A3/A4 fractures were more common in the equipoise group (92.0% vs 83.7%, P< .001). The agreement group had higher degree of certainty of PLC disruption [35.8% (SD 34.2) vs 27.6 (SD 27.3), P< .001] and more common use of the M1 modifier (44.3% vs 38.3%, P< .001). Overall, the degree of comminution was slightly higher in the equipoise group [47.8 (SD 20.5) vs 45.7 (SD 23.4), P< .001].Conclusions The agreement group had a higher degree of certainty of PLC injury and more common use of M1 modifier (more type B fractures). The equipoise group had more A3/A4 type fractures. Future studies are required to identify the role of comminution in decision making as degree of comminution was slightly higher in the equipoise group.

Published
2024
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41. AOSpine subaxial cervical spine injury classification system

Author

Vaccaro, Alexander R., Koerner, John D., Radcliff, Kris E., Oner, F. Cumhur, Reinhold, Maximilian, Schnake, Klaus J., Kandziora, Frank, Fehlings, Michael G., Dvorak, Marcel F., Aarabi, Bizhan, Rajasekaran, Shanmuganathan, Schroeder, Gregory D., Kepler, Christopher K., and Vialle, Luiz R.

Published
2016
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44. 187. An international validation of the AO Spine Upper Cervical Injury Classification

Author

Lambrechts, Mark, primary, Schroeder, Gregory D., additional, Karamian, Brian, additional, Canseco, Jose A., additional, Kepler, Christopher K., additional, Oner, F. Cumhur, additional, Benneker, Lorin M., additional, Rajasekaran, Shanmuganathan, additional, Dvorak, Marcel F., additional, Kandziora, Frank, additional, El-Sharkawi, Mohammad, additional, Bransford, Richard J., additional, Joaquim, Andrei F., additional, Takahata, Masahiko, additional, Hamouda, Waeel, additional, Schnake, Klaus J., additional, and Vaccaro, Alexander R., additional

Published
2022
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45. P151. Inspection of the global variability for the AO spine upper cervical injury classification

Author

Lambrechts, Mark, primary, Schroeder, Gregory D., additional, Karamian, Brian, additional, Canseco, Jose A., additional, Kepler, Christopher K., additional, Oner, F. Cumhur, additional, Vialle, Emiliano Neves, additional, Benneker, Lorin M., additional, Kandziora, Frank, additional, Joaquim, Andrei F, additional, Rajasekaran, Shanmuganathan, additional, Dvorak, Marcel F., additional, Bransford, Richard Jackson, additional, Takahata, Masahiko, additional, El-Sharkawi, Mohammad, additional, Hamouda, Waeel, additional, Schnake, Klaus J., additional, and Vaccaro, Alexander R., additional

Published
2022
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48. Spinal Post-traumatic Deformity

Author

De Gendt, Erin E.A., primary, Schroeder, Greg D., additional, Joaquim, Andrei, additional, Tee, Jin, additional, Kanna, Rishi M., additional, Kandziora, Frank, additional, Dhakal, Gaurav R., additional, Vialle, Emiliano N., additional, El-Sharkawi, Mohammad, additional, Schnake, Klaus J., additional, Rajasekaran, Shanmuganathan, additional, Vaccaro, Alex R., additional, Muijs, Sander P.J., additional, Benneker, Lorin M., additional, and Oner, F. Cumhur, additional

Published
2022
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49. Risk Factors for Failure in Conservatively Treated Osteoporotic Vertebral Fractures: A Systematic Review

Author

Scheyerer, Max J., Spiegl, Ulrich J. A., Grueninger, Sebastian, Hartmann, Frank, Katscher, Sebastian, Osterhoff, Georg, Perl, Mario, Pumberger, Matthias, Schmeiser, Gregor, Ullrich, Bernhard W., Schnake, Klaus J., Scheyerer, Max J., Spiegl, Ulrich J. A., Grueninger, Sebastian, Hartmann, Frank, Katscher, Sebastian, Osterhoff, Georg, Perl, Mario, Pumberger, Matthias, Schmeiser, Gregor, Ullrich, Bernhard W., and Schnake, Klaus J.

Abstract

Study Design: Systematic review. Objectives: Osteoporosis is one of the most common diseases of the elderly, whereby vertebral body fractures are in many cases the first manifestation. Even today, the consequences for patients are underestimated. Therefore, early identification of therapy failures is essential. In this context, the aim of the present systematic review was to evaluate the current literature with respect to clinical and radiographic findings that might predict treatment failure. Methods: We conducted a comprehensive, systematic review of the literature according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) checklist and algorithm. Results: After the literature search, 724 potentially eligible investigations were identified. In total, 24 studies with 3044 participants and a mean follow-up of 11 months (range 6-27.5 months) were included. Patient-specific risk factors were age >73 years, bone mineral density with a t-score <-2.95, BMI >23 and a modified frailty index >2.5. The following radiological and fracture-specific risk factors could be identified: involvement of the posterior wall, initial height loss, midportion type fracture, development of an intravertebral cleft, fracture at the thoracolumbar junction, fracture involvement of both endplates, different morphological types of fractures, and specific MRI findings. Further, a correlation between sagittal spinal imbalance and treatment failure could be demonstrated. Conclusion: In conclusion, this systematic review identified various factors that predict treatment failure in conservatively treated osteoporotic fractures. In these cases, additional treatment options and surgical treatment strategies should be considered in addition to follow-up examinations.

Published
2022

50. Update on Upper Cervical Injury Classifications: The New AO Upper Cervical Spine Classification System

Author

MS Orthopaedie Algemeen, Regenerative Medicine and Stem Cells, Vaccaro, Alexander R., Karamian, Brian A., Levy, Hannah A., Canseco, Jose A., Rajasekaran, Shanmuganathan, Benneker, Lorin M., Oner, F. Cumhur, Kandziora, Frank, Schnake, Klaus J., Kepler, Christopher K., Schroeder, Gregory D., MS Orthopaedie Algemeen, Regenerative Medicine and Stem Cells, Vaccaro, Alexander R., Karamian, Brian A., Levy, Hannah A., Canseco, Jose A., Rajasekaran, Shanmuganathan, Benneker, Lorin M., Oner, F. Cumhur, Kandziora, Frank, Schnake, Klaus J., Kepler, Christopher K., and Schroeder, Gregory D.

Published
2022

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