20 results on '"Schlein J"'
Search Results
2. Modular Physiological Control for Left Ventricular Assist Devices: A Clinical Pilot Trial
- Author
-
Maw, M., primary, Schloeglhofer, T., additional, Widhalm, G., additional, Wittmann, F., additional, Schlein, J., additional, Schaefer, A., additional, Riebandt, J., additional, Stadler, R., additional, Moscato, F., additional, Marko, C., additional, Zimpfer, D., additional, and Schima, H., additional
- Published
- 2022
- Full Text
- View/download PDF
3. Long-Term Outcomes after Surgical Repair of Supravalvular Aortic Stenosis in Pediatric Patients: 30 Years’ Single-Center Outcome
- Author
-
Schlein, J., additional, Wiedemann, D., additional, Gabriel, H., additional, Simon, P., additional, Wollenek, G., additional, Kitzmüller, E., additional, Michel-Behnke, I., additional, Laufer, G., additional, and Zimpfer, D., additional
- Published
- 2022
- Full Text
- View/download PDF
4. Exoskeletal Structures and Musculature
- Author
-
Rothschild, Miriam and Schlein, J.
- Published
- 1975
5. Execution of the Jump and Activity
- Author
-
Rothschild, Miriam, Schlein, J., Parker, K., Neville, C., and Sternberg, S.
- Published
- 1975
6. Long-Term Outcomes after Aortic Valve Repair in Pediatric Patients
- Author
-
Schlein, J., additional, Wiedemann, D., additional, Gabriel, H., additional, Wollenek, G., additional, Simon, P., additional, Michel-Behnke, I., additional, Laufer, G., additional, and Zimpfer, D., additional
- Published
- 2021
- Full Text
- View/download PDF
7. Age determination of some flies and mosquitos by daily growth layers of skeletal apodemes
- Author
-
Schlein, J. and Gratz, N. G.
- Subjects
Culicidae ,Age Determination by Skeleton ,Diptera ,parasitic diseases ,fungi ,Animals ,Articles - Abstract
A new method of determining age in certain Diptera, including Culex and Aedes mosquitos, involves counting-sometimes with the aid of staining techniques-the layers of cuticle growth that form daily at different points (inner apodemes) of the skeleton. If developed, the method would be of great importance for eradication and control programmes. The authors recommend further studies, in particular on the application of the technique to Anopheles and certain flies such as Calliphora.
- Published
- 1972
8. The utility of temporal trends of blood biomarkers as predictors for bloodstream infections in left ventricular assist device recipients.
- Author
-
Dimitrov K, Kaider A, Gross C, Rizvanovic S, Pepa F, Granegger M, Schlein J, Angleitner P, Wiedemann D, Riebandt J, Schlöglhofer T, Laufer G, and Zimpfer D
- Abstract
Background: Temporal trends of routinely obtained parameters may provide valuable information for predicting BSIs, but this association has not yet been established in LVAD patients., Methods: This retrospective analysis included data from 347 consecutive recipients of three rotary LVAD types. Study endpoints included the incidence of BSI, the association of temporal trends of routinely obtained blood biomarkers with the development of BSIs, the incidence of BSIs, and survival on LVAD support., Results: During follow-up, 47.8% (n = 166) of the patients developed BSI. In multivariate analyses, the development of BSI was a significant predictor of mortality (HR 5.78, 95% CI 4.08-8.19, p < 0.0001). In univariate analyses, after adjusting for potential confounders, albumin (SHR 0.94, 95% CI 0.91-0.97, p < 0.00010), creatinine (SHR 1.49, 95% CI 1.03-2.15, p = 0.033), and C-reactive protein (SHR 1.19, 95% CI 1.08-1.32, p = 0.0007) significantly predicted the development of BSIs during LVAD support. Notably, the strength of the association of parameter changes with the prediction of BSIs demonstrated a time-dependent correlation in the cases of albumin (p = 0.045) and creatinine (p = 0.003)., Conclusion: Bloodstream infections are highly prevalent among LVAD recipients and are independent predictors of mortality. Temporal biomarker trends significantly predict the development of BSIs. These findings suggest opportunities for interventions aiming to reduce the incidence of BSIs., (© 2024 The Author(s). Artificial Organs published by International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.)
- Published
- 2024
- Full Text
- View/download PDF
9. Aortic Valve Repair in Pediatric Patients: 30 Years Single Center Experience.
- Author
-
Schlein J, Kaider A, Gabriel H, Wiedemann D, Hornykewycz S, Simon P, Base E, Michel-Behnke I, Laufer G, and Zimpfer D
- Subjects
- Infant, Newborn, Child, Humans, Infant, Adolescent, Aortic Valve surgery, Retrospective Studies, Follow-Up Studies, Reoperation, Treatment Outcome, Cardiac Surgical Procedures methods, Aortic Valve Stenosis surgery, Heart Valve Prosthesis Implantation methods
- Abstract
Background: Valve repair is the procedure of choice for congenital aortic valve disease. With increasing experience, the surgical armamentarium broadened from simple commissurotomy to more complex techniques. We report our 30-year experience with pediatric aortic valve repair., Methods: A retrospective chart review of all patients aged less than 18 years who underwent aortic valve repair from May 1985 to April 2020 was conducted. Mortality was cross-checked with the national health insurance database (96% complete mortality follow-up in April 2020). Primary study endpoints were survival and incidence of reoperations., Results: From May 1985 until April 2020, 126 patients underwent aortic valve repair at a median age of 1.8 years (interquartile range, 0.2-10). Early mortality was 5.6% (7 of 126). All early deaths occurred in neonates with critical aortic stenosis undergoing commissurotomy. No early deaths were observed after 2002. Kaplan-Meier estimated survival was 90.8% (95% CI, 84.0-94.8) at 10 years, 86.9% (95% CI, 78.7-92.2) at 20 years, and 83.5% (95% CI, 71.7-90.6) at 30 years. The cumulative incidence of aortic valve replacement was 37% (95% CI, 27.7-46.3) at 10 years, 62.2% (95% CI, 50.1-72.1) at 20 years, and 67.4% (51.2-79.2) at 30 years. Nine patients had undergone re-repair of the aortic valve. The majority of valve replacements were Ross procedures., Conclusions: Our results support a repair-first strategy for patients with congenital heart disease and underline that aortic valve reconstruction can be a successful long-term solution. Longevity did not differ between aortic valve commissurotomy and complex aortic valve reconstruction., (Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
10. Long-term outcomes after surgical repair of subvalvular aortic stenosis in pediatric patients.
- Author
-
Schlein J, Wollmann F, Kaider A, Wiedemann D, Gabriel H, Hornykewycz S, Base E, Michel-Behnke I, Laufer G, and Zimpfer D
- Abstract
Objectives: Subvalvular aortic stenosis (SAS) can occur as discrete or tunnel-like obstruction of the left ventricular outflow tract and as progressive disease often leads to aortic valve regurgitation. We report our 30-year single-center experience after surgical repair of SAS., Methods: A retrospective chart review of all patients aged < 18 years, who underwent surgical repair of SAS from May 1985 to April 2020, was conducted. Mortality was cross-checked with the national health insurance database (93.8% complete mortality follow-up in April 2020). Survival and competing risks analysis were used to analyze the primary endpoints survival and incidence of reoperations., Results: From May 1985 until April 2020 103 patients (median age 5.5 years) underwent surgical repair of SAS. Survival was 90.8% at 10 years and 88.7% at 20 and 30 years. Age < 1 year at time of surgery, Shone's complex, mitral stenosis and concomitant mitral valve surgery were associated with mortality. The cumulative incidence of reoperation for SAS was 21.6% at 10 years, 28.2% at 20 and 30 years. The incidence of reoperation for SAS did not differ between the myectomy, membrane resection and combined myectomy and membrane resection groups. The cumulative incidence of reoperation on the aortic valve was 13.5% at 20 years., Conclusion: Recurrence rate of SAS is not to be neglected, though surgical repair of subaortic stenosis has good long-term results. Patients who needed a combined membrane resection and septal myectomy are not more prone to recurrence than patients who underwent solitaire myectomy or membrane resection., Competing Interests: DZ had received grants from Edwards Lifesciences, Medtronic, and Abbott. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Schlein, Wollmann, Kaider, Wiedemann, Gabriel, Hornykewycz, Base, Michel-Behnke, Laufer and Zimpfer.)
- Published
- 2022
- Full Text
- View/download PDF
11. First-in-man use of the EXCOR Venous Cannula for combined cavopulmonary and systemic ventricular support in Fontan circulation failure.
- Author
-
Karner B, Urganci E, Schlein J, Base E, Greil S, Michel-Behnke I, Granegger M, Laufer G, and Zimpfer D
- Subjects
- Cannula, Catheterization, Child, Humans, Male, Polytetrafluoroethylene, Vena Cava, Superior, Fontan Procedure, Heart-Assist Devices
- Abstract
Background and Aim: The Berlin Heart EXCOR system has been developed for mechanical circulatory support (MCS) of pediatric patients with terminal heart failure. A recently introduced iteration of the system (EXCOR Venous Cannula, Berlin Heart GmbH, Berlin, Germany) is dedicated to support patients with univentricular physiologies by facilitating implantation of the EXCOR device into the Fontan pathway., Case Presentation: We report the worldwide first successful implantation of the EXCOR Venous Cannula in a biventricular support concept for a 12-year-old boy (140 cm, 42.7 kg, body surface area 1.29 m
2 , Pedimacs Level 2) with severe systemic ventricle dysfunction and failing Fontan circulation. Surgery comprised of standard Berlin Heart EXCOR implantation to support the failing ventricle (12 mm apex / staged 12/9 mm arterial cannula / 50 ml ventricle). Cannulation for subpulmonary EXCOR support was achieved by performing a total cavopulmonary connection takedown with subsequent anastomosis of a staged 12/9 mm outflow cannula to the pulmonary artery and implantation of a 14/18 mm EXCOR Venous Cannula as subpulmonary inflow graft, which was connected to the superior vena cava and Fontan tunnel using GORE-TEX grafts. In the postoperative course, cardiac output and central venous pressures rapidly improved with hepatic and renal functions restoring to age- and condition-specific norm values., Conclusion: The Berlin Heart EXCOR Venous Cannula is the first system for standardized mechanical support of Fontan circulatory failure. In our patient, subpulmonary support restoring a biventricular circulation combined with systemic MCS normalized hemodynamics and reversed end-organ dysfunction., (Copyright © 2022 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.)- Published
- 2022
- Full Text
- View/download PDF
12. Reversal of pulmonary hypertension in paediatric patients with restrictive cardiomyopathy.
- Author
-
Schlein J, Riebandt J, Laufer G, and Zimpfer D
- Subjects
- Child, Humans, Retrospective Studies, Treatment Outcome, Cardiomyopathy, Restrictive complications, Cardiomyopathy, Restrictive diagnosis, Heart Failure complications, Heart Failure therapy, Heart Transplantation, Heart-Assist Devices, Hypertension, Pulmonary etiology
- Abstract
Left ventricular assist devices can reverse pulmonary hypertension in cardiac transplant candidates with heart failure with a reduced ejection fraction. Whether a similar approach is applicable in restrictive cardiomyopathy is uncertain. We report the successful implantation of a Medtronic HVAD left ventricular assist device in a bridge-to-candidacy concept in 2 paediatric patients with restrictive cardiomyopathy., (© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
13. Aortic valve replacement in pediatric patients: 30 years single center experience.
- Author
-
Schlein J, Simon P, Wollenek G, Base E, Laufer G, and Zimpfer D
- Subjects
- Aged, Aortic Valve surgery, Child, Humans, Reoperation, Retrospective Studies, Treatment Outcome, Bioprosthesis, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation
- Abstract
Background: The choice of aortic valve replacement needs to be decided in an interdisciplinary approach and together with the patients and their families regarding the need for re-operation and risks accompanying anticoagulation. We report long-term outcomes after different AVR options., Methods: A chart review of patients aged < 18 years at time of surgery, who had undergone AVR from May 1985 until April 2020 was conducted. Contraindications for Ross procedure, which is performed since 1991 at the center were reviewed in the observed non-Ross AVR cohort. The study endpoints were compared between the mechanical AVR and the biological AVR cohort., Results: From May 1985 to April 2020 fifty-five patients received sixty AVRs: 33 mechanical AVRs and 27 biological AVRs. In over half of the fifty-three AVRs performed after 1991 (58.5%; 31/53) a contraindication for Ross procedure was present. Early mortality was 5% (3/60). All early deaths occurred in patients aged < 1 year at time of surgery. Two late deaths occurred and survival was 94.5% ± 3.1% at 10 years and 86.4% ± 6.2% at 30 years. Freedom from aortic valve re-operation was higher (p < 0.001) in the mechanical AVR than in the biological AVR cohort with 95.2% ± 4.6% and 33.6% ± 13.4% freedom from re-operation at 10 years respectively., Conclusions: Re-operation was less frequent in the mechanical AVR cohort than in the biological AVR cohort. For mechanical AVR, the risk for thromboembolic and bleeding events was considerable with a composite linearized event rate per valve-year of 3.2%., (© 2021. The Author(s).)
- Published
- 2021
- Full Text
- View/download PDF
14. Long-term outcomes after the paediatric Ross and Ross-Konno procedures.
- Author
-
Schlein J, Ebner BE, Geiger R, Simon P, Wollenek G, Moritz A, Gamillscheg A, Base E, Laufer G, and Zimpfer D
- Subjects
- Adolescent, Aortic Valve diagnostic imaging, Aortic Valve surgery, Child, Female, Humans, Infant, Male, Reoperation, Treatment Outcome, Aortic Valve Stenosis surgery, Cardiac Surgical Procedures, Pulmonary Valve diagnostic imaging, Pulmonary Valve surgery, Ventricular Outflow Obstruction surgery
- Abstract
Objectives: The Ross procedure is an attractive option for the management of aortic valve disease in paediatric patients. We reviewed our experience with the paediatric Ross procedure to determine survival and freedom from reoperation in the third decade after surgery., Methods: We reviewed the data of 124 paediatric patients [71% male, median age at time of surgery 11.1 years (interquartile range 6-14.8 years); 63.7% bicuspid aortic valve], who underwent the Ross procedure at 2 tertiary centres from April 1991 to April 2020. The Ross-Konno procedures were performed on 14 (11.3%) patients. Deaths were cross-checked with the national health insurance database, and survival status was available for 96.8% of the patients. The median follow-up time was 12.1 years (interquartile range 3-18 years)., Results: There were 3 early and 6 late deaths. All early deaths occurred in patients aged <1 year at the time of surgery. The 25-year survival was 90.3%. Actuarial freedom from reoperation (linearized rates in parentheses) was as follows: Autograft reoperation was 90.8% (0.48%/patient-year) and right ventricular outflow tract (RVOT) reoperation was 67% (2.07%/patient year) at 25 years. The univariable Cox-proportional hazard analysis revealed younger age at time of surgery (P < 0.001), smaller implanted valve size (P < 0.001) and the use of a xenograft rather than a homograft (P < 0.001) as predictors of RVOT reoperation. At multivariable Cox-proportional hazard analysis, only age was an independent risk factor for RVOT reoperation (P = 0.041)., Conclusions: The Ross and the Ross-Konno procedures are associated with good outcomes in paediatric patients. Reoperation of the RVOT is frequent and associated with younger age., (© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
15. Surgical stented transcatheter valve-in-valve implantation in atrioventricular position in children.
- Author
-
Urganci E, Aschacher T, Hornykewycz S, Herbst C, Schlein J, Kahl B, Michel-Behnke I, Sandner S, Laufer G, and Zimpfer D
- Subjects
- Animals, Cattle, Humans, Infant, Jugular Veins surgery, Tricuspid Valve surgery, Bioprosthesis, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation methods, Hypoplastic Left Heart Syndrome surgery, Stents
- Abstract
The Melody valve (Medtronic, Minneapolis, MN, USA) is a stented bovine jugular vein graft that was primarily approved for transcatheter implantation in a pulmonary valve position. The prosthetic valve can also be implanted in an atrioventricular position in infants and young children, and in these cases it must be modified appropriately. In this tutorial we demonstrate the surgical preparation of a stented transcatheter Melody valve for implantation in the atrioventricular position. Additionally, we present a safe and effective method for surgical valve-in-valve implantation in a 3-year-old patient with hypoplastic left heart syndrome., (© The Author 2016. Published by MMCTS on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2020
- Full Text
- View/download PDF
16. Implantation of a decellularized aortic homograft in a child.
- Author
-
Urganci E, Aschacher T, Herbst C, Andreas M, Schlein J, Sandner S, Laufer G, and Zimpfer D
- Subjects
- Allografts, Aortic Valve Insufficiency etiology, Child, Echocardiography, Humans, Male, Transplantation, Homologous, Aortic Valve transplantation, Aortic Valve Insufficiency surgery, Aortic Valve Stenosis congenital, Aortic Valve Stenosis surgery, Balloon Valvuloplasty
- Abstract
The implantation of a decellularized aortic homograft in children and young adults has been shown to be a good alternative to existing surgical approaches. Lower risk of calcification and the potential of growth render a homograft a promising valve substitute. The child presented in this video tutorial is a 10-year-old boy diagnosed with congenital aortic stenosis which was treated by balloon valvuloplasty early in life. Current echocardiographic findings show severe aortic regurgitation and stenosis. The tutorial provides detailed insight into how to implant a decellularized aortic homograft as a total root replacement., (© The Author 2016. Published by MMCTS on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2020
- Full Text
- View/download PDF
17. The jumping mechanism of Xenopsylla cheopis. I. Exoskeletal structures and musculature.
- Author
-
Rothschild M and Schlein J
- Subjects
- Animals, Locomotion, Muscles anatomy & histology, Siphonaptera physiology, Species Specificity, Siphonaptera anatomy & histology
- Abstract
The jumping apparatus of the flea, which includes highly modified direct and indirect flight muscles, is described: attention is drawn to the various specializations of the exoskeleton which stiffen the thorax and also provide the 'click' mechanism triggering take-off. A finger-like invagination of tall cells within the cavity of the developing pleural arch of the pharate adult secretes the resilin pad. This is illustrated with coloured photographs. It is suggested that winglessness of a Mecopteran-like ancestor pre-adapted fleas to a parasitic life-style, and that a jumping mode of progression was a primitive feature of the whole Order. Scattered throughout the Siphonaptera today are species which have secondarily lost the pleural arch and with it the power to execute large jumps. These are usually found among fleas parasitizing mammals inhabiting caves, subterranean burrows and runs, high aerial nests and snow or ice-bound habitats. Large pleural arches are associated with fleas infesting large mobile hosts.
- Published
- 1975
- Full Text
- View/download PDF
18. [Use and knowledge of contraceptive methods in female students of children education].
- Author
-
Schilling A, Rubio L, and Schlein J
- Subjects
- Adult, Chile, Female, Humans, Students, Contraception methods, Contraception Behavior, Health Knowledge, Attitudes, Practice, Sexual Behavior
- Abstract
An inquire about contraception use and knowledge was applied to 292 female students. (Average of age = 21.3 years) An 88.4% of the woman with sexual activity had used contraceptive methods at least once. Principal reason for not going on using them, was not having sexual intercourse. In single women, the use of contraceptive methods was related with age, while the type selected was related with sexual intercourse's frequency. The most used contraceptive methods were rhythm and pill, which were not the best known ones.
- Published
- 1989
19. The jumping mechanism of Xenopsylla cheopis. III. Execution of the jump and activity.
- Author
-
Rothschild M, Schlein J, Parker K, Neville C, and Sternberg S
- Subjects
- Animals, Female, Locomotion, Male, Muscles anatomy & histology, Muscles ultrastructure, Siphonaptera anatomy & histology, Temperature, Siphonaptera physiology
- Abstract
The flea's hind legs are the chief source of jumping power, but in species which execute large jumps, take-off is accelerated by elastic energy released from a resilin pad (homologous with the wing hinge ligaments of flying insects) situated in the pleural arch. A central click mechanism, operated by a rapid twitch of the trochanteral depressor (the starter muscle), synchronizes the separate sources of energy which power the jump. Ciné photos confirm the morphological evidence that the flea takes off from the trochanters, not the tarsi. The loss of wings, associated with lateral compression of the body and the shortening of the pleural ridge (which thus lowers the position of the pleural arch) together with modifications of the direct and indirect flight muscles, are some of the main morphological features associated with the change from a flying to a saltatorial mode of progression. The flea's take-off basically resembles that of other Panorpoid insects (Diptera, Mecoptera, etc.). The release of elastic energy from the pleural arch is a system by which the force used to move the wings of flying insects is rapidly fed back into the legs and adds power to the jump.
- Published
- 1975
- Full Text
- View/download PDF
20. Age determination of some flies and mosquitos by daily growth layers of skeletal apodemes.
- Author
-
Schlein J and Gratz NG
- Subjects
- Animals, Age Determination by Skeleton, Culicidae growth & development, Diptera growth & development
- Abstract
A new method of determining age in certain Diptera, including Culex and Aedes mosquitos, involves counting-sometimes with the aid of staining techniques-the layers of cuticle growth that form daily at different points (inner apodemes) of the skeleton. If developed, the method would be of great importance for eradication and control programmes. The authors recommend further studies, in particular on the application of the technique to Anopheles and certain flies such as Calliphora.
- Published
- 1972
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.