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6. Beschaffung

Author

Demnick-Klas, G., primary, Bosch, M., additional, Geiss, E., additional, Eckstein, G., additional, Mohr, G., additional, Schütte, G., additional, Kokal, E., additional, Böhmer, M., additional, Schlaefer, K., additional, Waltl, P., additional, and Geiger, H., additional

Published
1991
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26. Cellular phones, cordless phones, and the risks of glioma and meningioma (Interphone Study Group, Germany)

Author

Schüz J, Böhler E, Berg G, Schlehofer B, Hettinger I, Schlaefer K, Wahrendorf J, Kunna-Grass K, and Blettner M

Abstract

The widespread use of cellular telephones has generated concern about possible adverse health effects, particularly brain tumors. In this population-based case-control study carried out in three regions of Germany, all incident cases of glioma and meningioma among patients aged 30-69 years were ascertained during 2000-2003. Controls matched on age, gender, and region were randomly drawn from population registries. In total, 366 glioma cases, 381 meningioma cases, and 1,494 controls were interviewed. Overall use of a cellular phone was not associated with brain tumor risk; the respective odds ratios were 0.98 (95% confidence interval (CI): 0.74, 1.29) for glioma and 0.84 (95% CI: 0.62, 1.13) for meningioma. Among persons who had used cellular phones for 10 or more years, increased risk was found for glioma (odds ratio = 2.20, 95% CI: 0.94, 5.11) but not for meningioma (odds ratio = 1.09, 95% CI: 0.35, 3.37). No excess of temporal glioma (p = 0.41) or meningioma (p = 0.43) was observed in cellular phone users as compared with nonusers. Cordless phone use was not related to either glioma risk or meningioma risk. In conclusion, no overall increased risk of glioma or meningioma was observed among these cellular phone users; however, for long-term cellular phone users, results need to be confirmed before firm conclusions can be drawn. [ABSTRACT FROM AUTHOR]

Published
2006
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27. Malformations in newborn: results based on 30,940 infants and fetuses from the Mainz congenital birth defect monitoring system (1990-1998).

Author

Queisser-Luft, A, Stolz, G, Wiesel, A, Schlaefer, K, and Spranger, J

Subjects
HUMAN abnormalities, COMPARATIVE studies, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, RESEARCH, EVALUATION research, ACQUISITION of data, DISEASE prevalence
Abstract

Prevalence rates of birth defects in the Federal Republic of Germany are informative to assess the general background risk of having a child with a birth defect. They provide basic figures to determine temporal and regional prevalence trends, to evaluate and initiate preventive measures and to initiate research projects. To avoid observer, definition and collection bias, active monitoring systems are required. Data collected in the active monitoring system of the Mainz Birth Defects Registry are presented. From 1990-1998, 30,940 live-births, stillbirths and abortions underwent standardized physical and sonographic examinations. Anamnestic data were collected from prenatal care records, maternity files and hospital records. Major malformations were diagnosed in 2144 (6.9%) and mild errors of morphogenesis in 11,104 (35.8%) of all infants. Risk factors associated with the occurrence of major malformations were identified by comparing anamnestic data from infants with and without major malformations. Using multivariate regression models, statistically significant associations were established for 9 risk factors. Causally related risk factors were parents or siblings with malformations, parental consanguinity, more than 3 minor errors of morphogenesis in the proband, maternal diabetes mellitus and ingestion of antiallergic drugs in the first trimester of pregnancy. Conjunctional risk factors were polyhydramnios, oligohydramnios and gestational age <32 weeks at birth. Using these risk factors, populations at risk for the occurrence of major malformation can be identified. [ABSTRACT FROM AUTHOR]

Published
2002
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29. On-going Research and Needs in Cancer Epidemiology — a World-wide Survey

Author

G. Wagner, C. S. Muir, C.O. Köhler, and Schlaefer K

Subjects
medicine.medical_specialty, Veterinary medicine, business.industry, Cancer, Disease, Descriptive epidemiology, medicine.disease, World wide, Chronic disease, Family medicine, Epidemiology of cancer, Epidemiology, Medicine, business, International agency
Abstract

The 908 epidemiological studies undertaken in 70 countries and reported in 1977 to the Clearing-House of On-going Research in Cancer Epidemiology, operated jointly by the International Agency for Research on Cancer and the Deutsches Krebsforschungszentrum, have been analysed. Descriptive epidemiology is undertaken in a fairly wide range of countries. Analytical studies are much more frequent in North America, the nordic countries and in the United Kingdom where there are a considerable number of investigations under way in industrial and non-industrial high-risk groups as well as case-control studies. Studies on breast and respiratory tract cancer are frequent but common sites like pancreas, malignant melanoma and prostate are currently largely ignored. The investment in epidemiological effort is trivial in relation to study opportunities and needs. The major impediments to epidemiological cancer research comprise: 1) an absence of trained investigators due to failure to teach chronic disease epidemiology at graduate and undergraduate level, and to create a career structure; 2) differing concepts of epidemiology; 3) secrecy of death certificates in certain countries, and other barriers preventing linkage of exposed persons and their subsequent disease experience.

Published
1979
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30. CHILDHOOD CANCER AND MAJOR MALFOR- MATIONS: A POPULATION-BASED ANALYSIS OF 33 254 NEWBORNS IN THE MAINZ BIRTH REGISTRY.

Author

Queisser-Luft, A., Stofz, G., Wiesel, A., Schlaefer, K., Fleck, B., Dittrich, M., Spix, C., and Wohrendorp, J.

Subjects
TUMORS in children, JUVENILE diseases, DISEASE risk factors, CENTRAL nervous system, NEUROBLASTOMA, BIRTH weight
Abstract

The article focuses on cancer in children. A causal relationship exists between some major malformations and some forms of cancer. Associations between specific major malformations and certain types of childhood cancer were studied. Of the 33254 infants, 51 (0.15%) developed cancer, 23 had solid tumors (45%), 11 had leukemia (22%), 6 had central nervous system tumors (12%) and 5 had neuroblastoma (9%). Children with major malformations have a significantly higher risk for developing cancer. High birth weight seems to be an important risk factor for developing childhood cancer.

Published
2004

32. Eigenschaften eines räumlichen stochastischen Stammzellsystems

Author

Pilz, L., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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34. Wachstumsmodelle mit stochastischen Differentialgleichungen

Author

Rosenkranz, G., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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35. Modellbildung und Simulation nichtlinearer physiologischer Systeme

Author

Möller, D. P. F., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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37. Der Verlauf der akuten Leukämie — ein stochastischer Ansatz

Author

Messerer, Dorothea, Neiß, A., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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38. Ein Simulationsmodell der Kinetik in Dünndarmkrypten

Author

Meinzer, H. P., Götz, Th., Sandblad, B., Zajicek, G., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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40. Ein Bildverarbeitungssystem zur Analyse von Gel-Elektrophoresen

Author

Engelmann, U., Meinzer, H. P., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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41. Testen zellkinetischer Hypothesen mit Hilfe von Regulationsmodellen

Author

Wichmann, H. E., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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42. Digitale Bildverarbeitung in der Histopathologie

Author

Zinser, G., Komitowski, D., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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43. Zur Musteranalyse mikroskopischer Muskelschnittbilder

Author

Ranft, U., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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45. Rechnerunterstütztes Patienten-Monitoring im Rahmen einer Leukämiestudie

Author

Zwingers, Th., Hammel, G., Messerer, Dorothea, Starz, I., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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47. Kontinuierliche Überwachung vitaler Parameter während der Anästhesie

Author

Hartung, H.-J., Osswald, P.-M., Bender, H.-J., Lutz, H., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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48. Integration eines Tumornachsorge-Registers in ein Klinikinformationssystem

Author

Griesser, G., Hedderich, J., Sauter, K., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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49. Rechnergestützte Informationssysteme für Intensivpflege — ein Beitrag zum Fortschritt der Medizin?

Author

Timmermann, U., Schillings, H., Ehlers, C. Th., Koller, S., editor, Reichertz, P. L., editor, Überla, K., editor, Anderson, J., editor, Goos, G., editor, Gremy, F., editor, Jesdinsky, H.-J., editor, Lange, H.-J., editor, Schneider, B., editor, Segmüller, G., editor, Wagner, G., editor, Köhler, C. O., editor, Tautu, P., editor, and Schlaefer, K., editor

Published
1984
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