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3. Donor site morbidity after the harvest of microvascular flaps from the medial and lateral femoral condyle region: Objective, radiologic, and patient-reported outcome of a multi-center trial

Author

Neuwirth, Maximilian, Ziegler, Thomas, Benedikt, Stefan, Winter, Raimund, Kamolz, Lars P., Schintler, Michael, Rab, Matthias, Mueller-Eggenberger, Michael, Mischitz, Madeleine, Palle, Wolfgang, Hoenck, Karina, Schoellnast, Helmut, Janek, Elmar, Borenich, Andrea, and Buerger, Heinz

Published
2022
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5. The Use of Fibrinolytic Agents in the Salvage of Free Flaps: A Systematic Review.

Author

Mandal, Patrick, Moshammer, Maximilian, Hecker, Andrzej, Smolle, Christian, Carnieletto, Martina, Mayrhofer, Marcel, Schintler, Michael, Winter, Raimund, and Kamolz, Lars Peter

Subjects
FIBRINOLYTIC agents, FREE flaps, DRUG repositioning, SCIENCE databases, WEB databases
Abstract

Background: Microvascular thrombosis following free tissue transfer presents a complex challenge for surgeons and carries the potential risk of flap failure. The application of fibrinolytic agents represents a robust therapeutic option. The aim of this systematic review is to provide a comprehensive overview of the clinical use of fibrinolytic drugs in the rescue of compromised free flaps. Methods: A systematic literature search for clinical studies detailing the utilization of fibrinolytic agents for salvaging free flaps was conducted using the PubMed and Web of Science databases. The inclusion criteria encompassed English-language publications that specifically addressed the clinical application of fibrinolytic agents for free-flap salvage. Results: A total of 331 articles were screened after excluding duplicates, with 56 meeting the inclusion criteria. Among these, 21 were clinical trials (evidence level III), and 35 were case studies (evidence level IV/V). In total, 459 flaps underwent treatment with fibrinolytic agents. Conclusion: The application of fibrinolytic agents appears to be a valuable intervention for rescuing compromised free flaps attributable to microvascular compromise. Notably, no prospective randomized trials have been published on this subject, and the evidence within the existing literature is characterized by its limited and heterogeneous nature. Further research is imperative to gather data on the efficacy, dosage, and safety profile of fibrinolytic agents. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Feasibility of collecting wound fluid during ongoing negative pressure wound therapy by the use of an additional container – A prospective observational study

Author

Wolfsberger, Christina Helene, primary, Maitz, Emanuel, additional, Schmachtl, Philipp, additional, Winkler, Sonja, additional, Luschnig, Daniel, additional, Sigl, Eva, additional, Heinzle, Andrea, additional, Gamerith, Clemens, additional, Tuca, Alexandru‐Cristian, additional, and Schintler, Michael V., additional

Published
2021
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15. Feasibility of collecting wound fluid during ongoing negative pressure wound therapy by the use of an additional container – A prospective observational study.

Author

Wolfsberger, Christina Helene, Maitz, Emanuel, Schmachtl, Philipp, Winkler, Sonja, Luschnig, Daniel, Sigl, Eva, Heinzle, Andrea, Gamerith, Clemens, Tuca, Alexandru‐Cristian, and Schintler, Michael V.

Subjects
NEGATIVE-pressure wound therapy, FLUIDS, QUESTIONNAIRES, DESCRIPTIVE statistics, COLLECTION & preservation of biological specimens, PATIENT safety, WOUND care, LONGITUDINAL method
Abstract

Negative‐pressure‐wound‐therapy is commonly used in clinical routine for wound management. Aim of the present study was to assess the feasibility and safety of using an additional container to collect wound fluid during ongoing negative‐pressure‐wound‐therapy. In this present prospective observational study, patients with negative‐pressure‐wound‐therapy were included. An additional container was inserted in the connecting tube between the wound and the vacuum generating device. The following 3 days, the container was changed daily and replaced by a new one. Further safety outcome parameters were assessed. A questionnaire was answered by the responsible surgeon. Twenty‐two patients with negative‐pressure‐wound‐therapy with a median (IQR) age of 58.5 (53.0‐70.0) years were included in the present study. In median, the duration of negative‐pressure‐wound‐therapy was 5.0 (4.6‐5.5) days. In mean ± SD the collected volume of the wound fluid in millilitres (mL) was on day one 7 ± 4 on day two 8 ± 7 and 10 ± 11 on day three. In one patient, there was <0.1 mL of clear water in the additional container. No safety concerns due to the additional container were observed. This study demonstrates that collecting wound fluid during ongoing negative‐pressure‐wound‐therapy over a time period of 3 days is feasible and safe. No safety concerns were observed. [ABSTRACT FROM AUTHOR]

Published
2022
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17. Gesellschaftsberichte

Author

Hinghofer-Szalkay, Helmut, Loder, Ingrid, Rössler, Andreas, Gallasch, Eugen, Einspieler, Christa, Prechtl, Heinz F. R., Scharfetter, Hermann, Rössler, Andreas, Moser, Maximilian, Frühwirth, Matthias, Gallasch, Eugen, Jernej, G., Kenner, Thomas, Bqjevskij, R., Reckenzaun, Evelyn, Friedrich, Gerhard, Habermann, Walter, Kiesler, Karl, Groll, R., Smolle-Jüttner, Freyja-Maria, Friedrich, Gerhard, Habermann, Walter, Griesbacher, Thomas, Dimai, Hans-Peter, Domej, W., Leb, Georg, Lau, K-HW., Knauer, A., Fladerer, Petra, Strempfl, C., Haas, D., Krause, Robert, Wenisch, Christoph, Knoflach-Reichart, Claudia, Lahousen, Theresa, Hofmann, Peter, Kopera, Daisy, Pilger, Ulrike, Krippl, P., Wolf, Gerald, Samonigg, Hellmut, Lahousen, Theresa, Knoflach-Reichart, Claudia, Jantscher, Martina, Lahousen, Theresa, Knoßach-Reichart, Claudia, Jantscher, Martina, Metzger, Peter, Messenbäck, Franz G., Prandl, Eva-Christina, Spendel, Stephan, Schintler, Michael V., Siegl, Alexander, Schinder, F., Wittgruber, Gabriela, Hellbom, Bengt, Scharnagl, Erwin, Prandl, Eva-Christina, Saurer, Thomas, Klinger, Richard, Schwarz, Sonja, Haid, Martin, Schinagl, Doris, Varosanec, Stjepan, Schwarz, Thomas, Aigner, Reingard M., Wolf, Gerald, Lorbach, Markus P., Seibert, Franz Josef, Boldin, Christian, Leithgöb, Ortnar, Grechenig, Wolfgang, Szyszkowitz, Rudolf, Steinbauer, Maria, Steinbrenner, Birgit, Schönauer-Cejpek, Martina, Martischnig, Alexandra, Temmel, Werner, Tauss, Josef, Portugaller, Horst R., Hausegger, Klaus A., Wolf, Gerald, Aigner, Reingard M., Nicoletti, Rudolf, Schwarz, Thomas, Lorbach, Mark P., Krippl, P., Wolf, Gerald, Aigner, Reingard M., Schwarz, Thomas, Lorbach, Mark P., Krippl, P., and Yazdani, Rene

Published
2003
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25. Evaluierung der Rekonstruktionstechniken am Ohrläppchen nach Piercing oder kosmetischer Aufdehnung

Author

Wimbauer, Julia M., Grohmann, Martin, Tuca, Alexandru-Cristian, Schintler, Michael, Rappl, Thomas, Winter, Raimund, Riml, Stefan, and Umschaden, Johann

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die Dehnung des Ohrläppchens und das daraus resultierende Entstehen von Fleischtunnel sind heutzutage ein trendiges Merkmal zur Körpermodifikation. Einige Patienten ändern jedoch im Laufe der Jahre ihre Meinung und äußern den Wunsch nach einer plastischen Korrektur.[zum vollständigen Text gelangen Sie über die oben angegebene URL], 48. Jahrestagung der Deutschen Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC), 55. Jahrestagung der Österreichischen Gesellschaft für Plastische, Ästhetische und Rekonstruktive Chirurgie, 22. Jahrestagung der Vereinigung der Deutschen Ästhetisch-Plastischen Chirurgen (VDÄPC)

Published
2017

26. Ohrkorrektur bei Neugeborenen mit einem Ohrmuschelformungssystem - Eine retrospektive Analyse

Author

Eylert, Gertraud, Lebo, Patricia, Maitz, Emanuel, Wolfsberger, Christina, Winter, Raimund, Laback, Christian, Schintler, Michael, Kamolz, Lars-Peter, and Spendel, Stephan

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die Inzidenzrate für Ohrmuscheldeformitäten liegt bei Kindern liegt zwischen 20-35%. Postnatal bestehen im Neugeborenenkreislauf noch für einige Wochen zirkulierende mütterliche Hormone. In dieser Phasen werden Östrogen ursächlich genannt, welche in der[zum vollständigen Text gelangen Sie über die oben angegebene URL], 48. Jahrestagung der Deutschen Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC), 55. Jahrestagung der Österreichischen Gesellschaft für Plastische, Ästhetische und Rekonstruktive Chirurgie, 22. Jahrestagung der Vereinigung der Deutschen Ästhetisch-Plastischen Chirurgen (VDÄPC)

Published
2017

27. PS02.244: PEDICLED FLAPS IN ESOPHAGEAL SURGERY: WHERE THORACIC-, PLASTIC- AND ENT- SURGEONS MEET

Author

Gschwandtner, Elisabeth, primary, Lindenmann, Jörg, additional, Fink-Neuböck, Nicole, additional, Fediuk, Melanie, additional, Porubsky, Christian, additional, Swatek, Paul, additional, Maier, Alfred, additional, Spendel, Stephan, additional, Schintler, Michael, additional, Thurnher, Dietmar, additional, and Smolle-Jüttner, Freyja-Maria, additional

Published
2018
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29. Ohrkorrektur ohne Operation - erste Erfahrungen mit einem Ohrmuschelformungssystem bei Neugeborenen mit Ohrmuscheldysplasien

Author

Spendel, Stephan, Lebo, Patricia, Schintler, Michael V., Rappl, Thomas, and Kamolz, Lars-Peter

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Fehlbildungen der Ohrmuscheln bei Kindern bleiben häufig unbeachtet. Obwohl statistische Erhebungen eine Inzidenzrate zwischen 20% und 35% belegen, wird einer Ohrdeformität oftmals nicht die erforderliche Aufmerksamkeit geschenkt. Eine Ohrmuschelfehlbildung könnte[for full text, please go to the a.m. URL], 45. Jahrestagung der Deutschen Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC), 19. Jahrestagung der Vereinigung der Deutschen Ästhetisch-Plastischen Chirurgen (VDÄPC), 52. Jahrestagung der Österreichischen Gesellschaft für Plastische, Ästhetische und Rekonstruktive Chirurgie (ÖGPRÄC)

Published
2014
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30. Wirkung von Spermidin bei 3° Verbrennungen (Tierexperimentelle Studie)

Author

Parvizi, Daryousch, Schintler, Michael, Justich, Ivo, Prandl, Eva, Aichner, Elisabeth, Wurzer, Paul, Tuca, Alexandru, Stacher, Elvira, Hager, Alexandra, Eisenberg, Tobias, Madeo, Frank, Trop, Marija, and Kamolz, Lars-Peter

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Hitzeeinwirkung auf Zellebene führt zu einer Denaturierung der Proteine und zu Schäden an der Zellmembran. Die Nekrosezone befindet sich im Zentrum der Wunde. An sie angrenzend befindet sich die Stasezone, gekennzeichnet durch verminderte Gewebsperfusion; sie besteht aus einer[for full text, please go to the a.m. URL], 45. Jahrestagung der Deutschen Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC), 19. Jahrestagung der Vereinigung der Deutschen Ästhetisch-Plastischen Chirurgen (VDÄPC), 52. Jahrestagung der Österreichischen Gesellschaft für Plastische, Ästhetische und Rekonstruktive Chirurgie (ÖGPRÄC)

Published
2014
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31. Anatomy of the Vascularized Lateral Femoral Condyle Flap

Author

Parvizi, Daryousch, primary, Vasilyeva, Anna, additional, Wurzer, Paul, additional, Tuca, Alexandru, additional, Lebo, Patricia, additional, Winter, Raimund, additional, Clayton, Robert P., additional, Rappl, Thomas, additional, Schintler, Michael V., additional, Kamolz, Lars-P., additional, and Buerger, Heinz K., additional

Published
2016
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32. Modernes Management großer postinterventioneller Leistenhämatome

Author

Schramayer, Georg, Koter, Stephan Herwig, Cohnert, Tina, and Schintler, Michael

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Zugänge über die Leistengefäße zum Zwecke von Interventionen sind im Zunehmen begriffen. Dabei treten mitunter sehr große Hämatome auf, die einer umgehenden gefäßchirurgischen Sanierung bedürfen. Material und Methoden: Wir berichten über[for full text, please go to the a.m. URL], 130. Kongress der Deutschen Gesellschaft für Chirurgie

Published
2013
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33. Sensor materials for the detection of human neutrophil elastase and cathepsin G activity in wound ¿uid

Author

Wehrschuetz-Sigl, Eva, Guebitz, Georg M., Van der Palen, Job, Hasmann, Andrea, Gewessler, Ulrike, Hulla, Elisabet, Schneider, Konstantin P., Binder, Barbara, Francesko, Antonio, Tzanov, Tzanko, Schintler, Michael, Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, and Universitat Politècnica de Catalunya. GBMI - Grup de Biotecnologia Molecular i Industrial

Subjects
Cathepsin G, Ciències de la salut::Medicina::Dermatologia [Àrees temàtiques de la UPC], Leucocyte elastase, ELA2, Human neutrophil elastase, Elastasi neutrofila, CTSG
Abstract

Human neutrophil elastase (HNE) and cathepsin G (CatG) are involved in the pathogenesis of a number of inflammatory disorders. These serine proteinases are released by neutrophils and monocytes in case of infection. Wound infection is a severe complication regarding wound healing causing diagnostic and therapeutic problems. In this study we have shown the potential of HNE and CatG to be used as markers for early detection of infection. Significant differences in HNE and CatG levels in infected and non-infected wound fluids were observed. Peptide substrates for these two enzymes were successfully immobilised on different surfaces, including collagen, modified collagen, polyamide polyesters and silica gel. HNE and CatG activities were monitored directly in wound fluid via hydrolysis of the chromogenic substrates. Infected wound fluids led to significant higher substrate hydrolysis compared with non-infected ones. These different approaches could be used for the development of devices which are able to detect elevated enzyme activities before manifestation of infection directly on bandages. This would allow a timely intervention by medical doctors thus preventing severe infections.

Published
2011
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36. Sensor materials for the detection of human neutrophil elastase and cathepsin G activity in wound ¿uid

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, Universitat Politècnica de Catalunya. GBMI - Grup de Biotecnologia Molecular i Industrial, Wehrschuetz-Sigl, Eva, Guebitz, Georg M., Van der Palen, Job, Hasmann, Andrea, Gewessler, Ulrike, Hulla, Elisabet, Schneider, Konstantin P., Binder, Barbara, Francesko, Antonio, Tzanov, Tzanko, Schintler, Michael, Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, Universitat Politècnica de Catalunya. GBMI - Grup de Biotecnologia Molecular i Industrial, Wehrschuetz-Sigl, Eva, Guebitz, Georg M., Van der Palen, Job, Hasmann, Andrea, Gewessler, Ulrike, Hulla, Elisabet, Schneider, Konstantin P., Binder, Barbara, Francesko, Antonio, Tzanov, Tzanko, and Schintler, Michael

Abstract

Human neutrophil elastase (HNE) and cathepsin G (CatG) are involved in the pathogenesis of a number of inflammatory disorders. These serine proteinases are released by neutrophils and monocytes in case of infection. Wound infection is a severe complication regarding wound healing causing diagnostic and therapeutic problems. In this study we have shown the potential of HNE and CatG to be used as markers for early detection of infection. Significant differences in HNE and CatG levels in infected and non-infected wound fluids were observed. Peptide substrates for these two enzymes were successfully immobilised on different surfaces, including collagen, modified collagen, polyamide polyesters and silica gel. HNE and CatG activities were monitored directly in wound fluid via hydrolysis of the chromogenic substrates. Infected wound fluids led to significant higher substrate hydrolysis compared with non-infected ones. These different approaches could be used for the development of devices which are able to detect elevated enzyme activities before manifestation of infection directly on bandages. This would allow a timely intervention by medical doctors thus preventing severe infections., Peer Reviewed, Postprint (published version)

Published
2011

38. Novel protease-based diagnostic devices for detection of wound infection

Author

Heinzle, Andrea, primary, Papen-Botterhuis, Nicole E., additional, Schiffer, Doris, additional, Schneider, Konstantin P., additional, Binder, Barbara, additional, Schintler, Michael, additional, Haaksman, Ingrid K., additional, Lenting, Herman B., additional, Gübitz, Georg M., additional, and Sigl, Eva, additional

Published
2013
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43. Ultrasound-Navigated Interstitial Nd:YAG LaserCoagulation of Congenital Vascular Disorders

Author

Spendel, Stephan, primary, Prandl, Eva-Christina, additional, Uggowitzer, Martin, additional, Kugler, Christian, additional, Schintler, Michael V., additional, Siegl, Alexander, additional, Hellbom, Bengt, additional, Schimpl, Günther, additional, Mayr, Johannes M., additional, Klein, Erich G., additional, Aschauer, Michaela, additional, and Scharnagl, Erwin, additional

Published
2001
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46. 6 Jahre "Zertifizierte/r Wundmanager/-in®".

Author

Kammerlander, Gerhard, Petek, Cäcilia, Schaflinger, Erich, Hirschberger, Günther, Nolte, Thomas, Gröchenig, Ernst, Andriessen, Anneke, Allmer, Gertrude, Asmussen, Peter D., Klier, Harald, Peischl, Renate, Brunner, Urs, Eberlein, Thomas, Spendel, Stephan, and Schintler, Michael

Abstract

Copyright of GMS Krankenhaushygiene Interdisziplinaer is the property of German Medical Science Publishing House gGmbH and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2006

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