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A new controller of an ON/OFF type was implemented for halothane anesthesia. A proportional-plus-integral controller with time-delay compensation proved not to be robust enough for the known clinical situation, as shown both in computer simulations and in animal trials. The ON/OFF controller proved to be less sensitive to parameter mismatches, and repeated animal trials showed a short response time and acceptable steady-state tracking. A method for switching the controlled effect of the drug was also developed, since anesthetic agents have multiple effects. Mean arterial blood pressure and a measure of EEG frequency were chosen as controlled variables, both being depressed by halothane. A coordinator forces the system state as near the desired values of these variables as possible, given that only one drug is used.

A procedure is presented for designing distortion-invariant correlation filters. Optical correlation filters designed using this technique retain full position invariance. The filter design begins by finding the distortion-invariant modes (eigenfunctions) for a particular image. The input image, filter, and correlation response are all spectrally expanded in terms of these orthogonal eigenfunctions. An iterative technique between the spatial domain and the spectral domain is used to rephase the invariant modes so that a filter composed of a linear combination of modes has the proper overall invariance. The iterative technique also controls the information content of the filter by maintaining specified amplitudes for each invariant mode in the filter. Targets are detected by spanning the filter to determine points of constant amplitude.

Iteratively designed filters are incorporated into an optical correlator for position, rotation, and intensity invariant recognition of target images. The filters exhibit excellent discrimination because they are designed to contain full information about the target image. Numerical simulations and experiments demonstrate detection of targets that are corrupted with random noise (SNR approximately 05) and also partially obscured by other objects. The complex valued filters are encoded in a computer generated hologram and fabricated directly using an electron-beam system. Experimental results using a liquid crystal spatial light modulator for realtime input show excellent agreement with analytical and numerical computations.