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1. Evaluation and care of international living kidney donor candidates: Strategies for addressing common considerations and challenges.

Author

Henderson, Macey, Nishio-Lucar, Angie, Cooper, Matthew, Lentine, Krista, Shukhman, Ellen, Hunt, Julia, LaPointe-Rudow, Dianne, Mandelbrot, Didier, Hays, Rebecca, Kumar, Vineeta, Schaefer, Heidi, and Al Ammary, Fawaz

Subjects
international donor, living donor kidney transplantation, living kidney donation, logistics, medical evaluation, Consensus, Humans, Kidney Transplantation, Living Donors, United States
Abstract

End-stage kidney disease patients in the United States may have family members or friends who are not US citizens or residents but are willing to serve as their living kidney donor in the United States (international donors). In July 2017, the American Society for Transplantation (AST) Live Donor Community of Practice (LDCOP) convened a multidisciplinary workgroup of experts in living donation care, including coordinators, social workers, donor advocates, administrators, and physicians, to evaluate educational gaps related to the evaluation and care of international donors. The evaluation of international living donor candidates is a resource-intensive process that raises key considerations for assessing risk of exploitation/inducement and addressing communication barriers, logistics barriers, and access to care in their home country. Through consensus-building discussions, we developed recommendations related to: (a) establishing program guidelines for international donor candidate evaluation and selection; (b) initial screening; (c) logistics planning; (d) comprehensive evaluation; and (e) postdonation care and follow-up. These recommendations are not intended to direct formal policy, but rather as guidance to help programs more efficiently and effectively structure and execute evaluations and care coordination. We also offer recommendations for research and advocacy to optimize the care of this unique group of living donors.

Published
2020

5. Kidney Transplantation From Hepatitis C Viremic Deceased Donors to Aviremic Recipients in a Real-world Setting

Author

Concepcion, Beatrice P., Binari, Laura A., Schaefer, Heidi, Rega, Scott, Feurer, Irene, Shawar, Saed, Naik, Ruchi, Hickman, Laura, Walker, Jasmine, Kapp, Meghan, Birdwell, Kelly A., Langone, Anthony, Helderman, J. Harold, Ann Sarrell, Bonnie, Kochar, Guneet, Dubray, Bernard, Smith, Kristin, O’Dell, Heather, DeMers, April, Shelton, Princess, Perri, Roman, Shaffer, David, and Forbes, Rachel C.

Published
2021
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7. A2/A2B to B kidney transplantation outcomes: A single center 7‐year experience.

Author

El Chediak, Alissar, Shawar, Saed, Fallahzadeh, Mohammad K., Forbes, Rachel, Schaefer, Heidi M., Feurer, Irene D., Rega, Scott, Triozzi, Jefferson L., and Shaffer, David

Subjects
KIDNEY transplantation, TREATMENT effectiveness, GRAFT survival, OVERALL survival, SURVIVAL rate
Abstract

Introduction: Data on long‐term outcomes following A2/A2B to B kidney transplants since the 2014 kidney allocation system (KAS) changes are few. The primary aim of this study is to report our 7‐year experience with A2/A2B to B kidney transplants and to compare post‐transplant outcomes of A2/A2B to a concurrent group of B to B kidney transplants. Additionally, the study evaluates the impact of pre‐transplant anti‐A1 titers on survival outcomes in A2/A2B transplants. Methods: This retrospective, single‐center analysis included all adults who received A2/A2B to B deceased donor kidney transplants from December 2014 to June 2021 compared to B to B recipients. The effects of pre‐transplant IgM/IgG titers, stratified as ≤1:8 and ≥1:16, on death‐censored, rejection‐free, and overall graft survival were tested. Results: Fifty‐three A2/A2B and 114 B to B adults were included with a median follow‐up time of 32 months. Overall graft survival, patient survival, and rejection‐free graft survival did not differ between the two groups. There were no differences between the groups' overall kidney function values (p >.80) or their temporal trajectories (time by group interaction p >.11). Unadjusted death‐censored graft survival was lower in A2/A2B to B compared to B recipients (p =.03), but the effect was not significant (p =.195) after adjusting for any readmissions (p =.96), rejection episodes (p <.001) or BK infection (p =.76). We did not detect an effect of pre‐transplant titer group on death‐censored (p =.59), rejection‐free (p =.61), or overall graft survival (p =.26) Conclusions: A2/A2B to B kidney transplants have comparable overall patient and graft survival, rejection‐free graft survival, and longitudinal renal function compared to B to B transplants at our center. Allograft survival outcomes were not significantly different between patients with low and high pre‐transplant anti‐A1 IgM/IgG titers. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Twelve‐month kidney and liver outcomes of kidney transplantation from Hepatitis C Viremic deceased donors to aviremic recipients.

Author

Binari, Laura A., Thorne, Peter, Rega, Scott A., Feurer, Irene D., Shawar, Saed, Naik, Ruchi, Birdwell, Kelly A., Helderman, J. Harold, Langone, Anthony, Sarrell, Bonnie Ann, Schaefer, Heidi, DuBray, Bernard John, Eid, Kareem, Hickman, Laura, Shaffer, David, Concepcion, Beatrice P., and Forbes, Rachel C.

Subjects
KIDNEY transplantation, HEPATITIS C, KIDNEYS, GLOMERULAR filtration rate, ALANINE aminotransferase, LIVER, ASPARTATE aminotransferase
Abstract

Introduction: Utilization of hepatitis C viremic (HCV+) deceased donor kidneys (DDKT) for aviremic recipients increases opportunities for transplantation with excellent short‐term outcomes. Our primary aim was to understand longer‐term outcomes, specifically assessing kidney and liver function in the first year posttransplant. Methods: This was a retrospective single‐center study of adult DDKT recipients of HCV+ kidneys (cases) matched 1:1 to recipients of HCV‐ kidneys (comparators). Between‐group outcomes were analyzed using comparisons of means and proportions, survival analysis methods, and multivariable mixed effects models. Results: Sixty‐five cases and 65 comparators had statistically comparable demographic and clinical characteristics. There were no between‐group differences in serum creatinine or estimated glomerular filtration rate at month 12 (p =.662) or in their trajectories over months 1–12 (p >.292). Within the first 60 days, rates of liver function values >3 times upper limit of normal among cases were comparable to comparators for aspartate aminotransferase (AST) (14% vs. 6%, p =.242) and higher for alanine transaminase (ALT) (23% vs. 6%, p =.011). AST declined during the first 8 weeks (p =.005) and stabilized for both groups (p =.406) during the following 10 months. ALT declined during the first 8 weeks (p <.001), continued to decline over months 3–12 (p =.016), and the trajectory was unrelated to antiviral therapy initiation among cases. Conclusions: Aviremic recipients of HCV+ kidneys had comparable kidney outcomes to matched recipients of HCV‐ kidneys. Despite more HCV+ recipients having an elevation in ALT within the first 60 days, ALT values normalized with no identified liver complications attributed to HCV. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Novel Once-Daily Extended-Release Tacrolimus Versus Twice-Daily Tacrolimus in De Novo Kidney Transplant Recipients: Two-Year Results of Phase 3, Double-Blind, Randomized Trial

Author

Denny, Jason E., Kulkarni, Sanjay, Hricik, Donald, Bresnahan, Barbara A., Bunnapradist, Suphamai, El-Sabrout, Rafik A., Chan, Laurence K., Ciancio, Gaetano, El-Ghoroury, Mohamed A., Goldstein, Michael J., Gaston, Robert S., Gohh, Reginald Y., Killackey, Mary T., King, Anne, Knight, Richard J., Kore, Arputharaj H., Sudan, Debra L., Chapochnick Friedmann, Javier, Mulgaonkar, Shamkant P., Nolan, Charles, Pankewycz, Oleh G., Pirsch, John D., Schaefer, Heidi M., Steinberg, Steven M., Gelb, Bruce E., True, Karin A., West-Thielke, Patricia M., Waybill, Mary M., Wolf, Joshua H., Ketel, Beverley L., Harland, Robert C., Shihab, Fuad S., Cassuto, Elisabeth, Le Meur, Yannick, Rostaing, Lionel, Mariat, Christophe, Grinyó, Josep Maria, Puig, Jose, Seron, Daniel, Tisone, Giuseppe, Ciechanowski, Kazimierz, Foroncewicz, Bartosz, Wlodarczyk, Zbigniew, Budde, Klemens, Witzke, Oliver, Mondragon, Guillermo A., Mancilla Urrea, Eduardo, Alberu Gomez, Josefina, Reyes Acevedo, Rafael, Rial, Maria del Carmen, Novoa, Pablo A., Silva, Helio T., Jr., Garcia, Valter D., Carvalho, Deise D., Santamaria Saber, Luciana T., Contieri, Fabiana L., Bastos, Marcos G., Manfro, Roberto C., Kanellis, John, Eris, Josette, O’Connell, Philip, Hughes, Peter, Russ, Graeme, Pidgeon, Grant B., Dittmer, Ian D., Kee, Terence, Vathsala, Anantharaman, Naumovic, Radomir, Mitic, Igor, Parmjeet, Randhawa, Grinyó, Josep M., and Silva, Helio Tedesco, Jr.

Published
2016
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10. List of Contributors

Author

Alexopoulos, Sophoclis, primary, Alhamed, Tarek, additional, Alicic, Radica Z., additional, Amarah, Amatur, additional, Ananthakrishnan, Shubha, additional, Arduino, Matthew J., additional, Rosenthal Asher, Deborah S., additional, Axelrod, David, additional, Balogun, Rasheed Abiodun, additional, Bargman, Joanne M., additional, Beathard, Gerald A., additional, Beaulieu, Monica C., additional, Belcher, Justin M., additional, Berns, Jeffrey S., additional, Bieber, Scott D., additional, Bloom, Roy D., additional, Blumberg, Emily A., additional, Bowman, Brendan, additional, Carrero, Juan J., additional, Cedillo-Couvert, Esteban, additional, Chan, Christopher T., additional, Chandraker, Anil, additional, Chopra, Tushar, additional, Cobo, Gabriela, additional, Cohen, Lewis M., additional, Collins, Allan J., additional, Concepcion, Beatrice P., additional, Connor, Michael J., additional, Coresh, Josef, additional, Cukor, Daniel, additional, Dawson, Solomon, additional, de Boer, Ian, additional, Denburg, Michelle, additional, Depner, Thomas A., additional, Dharnidharka, Vikas R., additional, Germain, Michael J., additional, Gill, John S., additional, Goral, Simin, additional, Grafals, Monica, additional, Graham, Judi M., additional, Hall, Gentzon, additional, Heimbürger, Olof, additional, Hingorani, Sangeeta R., additional, Hudson, Joanna Q., additional, Inker, Lesley A., additional, Jankowska, Magdalena, additional, Johnson, Emily J., additional, Johnston, Olwyn, additional, Jones, Clare B., additional, Jovanovich, Anna, additional, Kam-Tao Li, Philip, additional, Karp, Seth J., additional, Kendrick, Jessica, additional, Kimmel, Paul L., additional, Klatte, Derk C.F., additional, Knoll, Greg, additional, Kraus, Michael A., additional, Lash, James P., additional, Lentine, Krista L., additional, Levey, Andrew S., additional, Levin, Adeera, additional, Lim, Mary Ann, additional, Lindhom, Bengt, additional, Liu, Kathleen, additional, MacLaughlin, Helen, additional, Marsh, Nicola, additional, Matsuoka, Lea, additional, Mawad, Habib, additional, Mehrotra, Rajnish, additional, Moe, Sharon, additional, Najafian, Nadar, additional, Nataatmadja, Melissa, additional, Nguyen, Duc B., additional, Okusa, Mark Douglas, additional, Oliver, Matthew J., additional, Palevsky, Paul M., additional, Parikh, Chirag R., additional, Patel, Priti R., additional, Porter, Anna C., additional, Quinn, Robert R., additional, Riella, Leonardo V., additional, Rhee, Eugene P., additional, Rivara, Matthew B., additional, Rosner, Mitchell H., additional, Roumelioti, Maria-Eleni, additional, Roumeliotis, Athanasios K., additional, Sarnak, Mark J., additional, Sawinski, Deirdre, additional, Schaefer, Heidi, additional, Shafi, Tariq, additional, Sheerin, Neil, additional, Siew, Edward D., additional, Srivastava, Anand, additional, Starr, Michelle C., additional, Stenvinkel, Peter, additional, St. Peter, Wendy L., additional, Szeto, Cheuk-Chun, additional, Tolwani, Ashita J., additional, Trinh, Emilie, additional, Tuttle, Katherine R., additional, Unruh, Mark L., additional, Vella, John P., additional, Waikar, Sushrut S., additional, Yee-Moon Wang, Angela, additional, Wasse, Monnie, additional, Wazny, Lori, additional, Weiner, Daniel E., additional, Weinhandl, Eric, additional, Weiss, Jessica W., additional, Wetmore, James B., additional, Wong, Tiffany C., additional, Woodell, Tyler B., additional, Xu, Hong, additional, Yeun, Jane Y., additional, and Zalunardo, Nadia, additional

Published
2019
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12. Effects of Voice and Biographic Data on Face Encoding

Author

Karlsson, Thilda, Schaefer, Heidi, Barton, Jason J. S., Corrow, Sherryse L., Karlsson, Thilda, Schaefer, Heidi, Barton, Jason J. S., and Corrow, Sherryse L.

Abstract

There are various perceptual and informational cues for recognizing people. How these interact in the recognition process is of interest. Our goal was to determine if the encoding of faces was enhanced by the concurrent presence of a voice, biographic data, or both. Using a between-subject design, four groups of 10 subjects learned the identities of 24 faces seen in video-clips. Half of the faces were seen only with their names, while the other half had additional information. For the first group this was the persons voice, for the second, it was biographic data, and for the third, both voice and biographic data. In a fourth control group, the additional information was the voice of a generic narrator relating non-biographic information. In the retrieval phase, subjects performed a familiarity task and then a face-to-name identification task with dynamic faces alone. Our results consistently showed no benefit to face encoding with additional information, for either the familiarity or identification task. Tests for equivalency indicated that facilitative effects of a voice or biographic data on face encoding were not likely to exceed 3% in accuracy. We conclude that face encoding is minimally influenced by cross-modal information from voices or biographic data., Funding Agencies|Natural Sciences and Engineering Research Council [RGPIN 319129]; Canada Research Chair [950-228984]; Marianne Koerner Chair in Brain Diseases; National Eye Institute [F32 EY023479-02]

Published
2023
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19. Effects of Faces and Voices on the Encoding of Biographic Information

Author

Fransson, Sarah, Corrow, Sherryse, Yeung, Shanna, Schaefer, Heidi, Barton, Jason J. S., Fransson, Sarah, Corrow, Sherryse, Yeung, Shanna, Schaefer, Heidi, and Barton, Jason J. S.

Abstract

There are multiple forms of knowledge about people. Whether diverse person-related data interact is of interest regarding the more general issue of integration of multi-source information about the world. Our goal was to examine whether perception of a persons face or voice enhanced the encoding of their biographic data. We performed three experiments. In the first experiment, subjects learned the biographic data of a character with or without a video clip of their face. In the second experiment, they learned the characters data with an audio clip of either a generic narrators voice or the characters voice relating the same biographic information. In the third experiment, an audiovisual clip of both the face and voice of either a generic narrator or the character accompanied the learning of biographic data. After learning, a test phase presented biographic data alone, and subjects were tested first for familiarity and second for matching of biographic data to the name. The results showed equivalent learning of biographic data across all three experiments, and none showed evidence that a characters face or voice enhanced the learning of biographic information. We conclude that the simultaneous processing of perceptual representations of people may not modulate the encoding of biographic data., Funding Agencies|Natural Sciences and Engineering Research Council [RGPIN 319129]; Canada Research Chair [950-228984]; Marianne Koerner Chair in Brain Diseases; National Eye Institute [F32 EY023479-02]

Published
2022
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24. Cortical auditory evoked potential morphology : response characteristics of the P1-N1-P2-N2 waves as determined by stimulus and subject parameters

Author

Schaefer, Heidi

Abstract

Analysis of cortical auditory evoked potentials (CAEPs) can provide valuable insight into how sounds are processed differently based on subject and stimulus parameters. Having a thorough understanding of these norms is necessary to use techniques for detecting a variety of neurological impairments, for evaluating hearing thresholds in patients who are unreliable or difficult to assess behaviourally, and for monitoring brain plasticity. Specifically, areas of central processing that can be investigated using electrophysiological methods include the ability to detect sounds, discriminate between sounds, and the ability to recognize and notice similarities or differences in sound patterns. There is also potential for CAEPs to be used to monitor speech processing. Possible applications of monitoring speech using CAEPs include validating hearing aids, assessing neural plasticity in hearing aid and cochlear implant users over time, and determining the efficacy of auditory training in improving speech perception. In order to effectively record and analyze CAEPs for any purpose, it is essential that clinicians have a thorough understanding of how stimulus factors such as intensity, duration, frequency, and presentation rate affect the positive and negative components of CAEPs. Furthermore, clinicians must be well versed in their understanding of CAEP maturational changes, as components show changes in latency, amplitude, and variability over the life span. On account of CAEPs being generated from higher level cortical areas, they are also highly mediated by subject state and attention. As such, it is critical that these factors be taken into consideration when comparing data across participants, and when comparing individual data with norms. Through the process of conducting a scoping review, this thesis outlines morphological trends of CAEPs as a function of both stimulus and subject parameters, highlights the interdependency of such variables, and identifies avenues for further research. Furthermore, data has been compiled into a freely available resource which clinicians may contribute to as additional research is conducted.

Published
2021
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26. List of Contributors

Author

Abbate, Mauro, primary, Adrogué, Horacio J., additional, Alper, Seth L., additional, Alpern, Robert J., additional, Baliga, Radhakrishna, additional, Batlle, Daniel, additional, Bernardo, José F., additional, Berndt, Theresa J., additional, Bevensee, Mark O., additional, Biber, Jürg, additional, Bindels, René J.M., additional, Birn, Henrik, additional, Boron, Walter F., additional, Craig Brater, D., additional, Brown, Edward M., additional, Burckhardt, Gerhard, additional, Camargo, Simone M.R., additional, Caplan, Michael J., additional, Cárdenas, Andrés, additional, Chen, Sheldon, additional, Ilsø Christensen, Erik, additional, Chung-Park, Moonja, additional, Coe, Fredric L., additional, Conrad, Kirk P., additional, Cooper, Christopher J., additional, Curthoys, Norman P., additional, Devarajan, Prasad, additional, Diamond, Matthew, additional, Dumitru, Cristina, additional, Dworkin, Lance D., additional, Eckardt, Kai-Uwe, additional, Huba Endre, Zoltán, additional, Evan, Andrew, additional, Falk, Ronald J., additional, Forster, Ian C., additional, Friedman, Peter A., additional, Kazue Fujihara, Clarice, additional, Geibel, John P., additional, Giacomini, Kathleen M., additional, Ginès, Pere, additional, Goral, Simin, additional, Halperin, Mitchell, additional, Hamm, L. Lee, additional, Haque, Syed K., additional, Hebert, Steven C., additional, Harold Helderman, J., additional, Henrich, William L., additional, Hernando, Nati, additional, Hoenderop, Joost G.J., additional, Homeister, Jonathon W., additional, Hummel, Charles S., additional, Jennette, J. Charles, additional, Kamel, Kamel S., additional, Ananth Karumanchi, S., additional, Kashtan, Clifford E., additional, Khoury, Charbel, additional, Kleta, Robert, additional, Koepsell, Hermann, additional, Konrad, Martin, additional, Krapf, Reto, additional, Kumar, Rajiv, additional, Kurtz, Armin, additional, Kurtz, Ira, additional, Langone, Anthony J., additional, Lin, Shih-Hua, additional, Lindheimer, Marshall D., additional, Lu, Christopher Y., additional, Macconi, Daniela, additional, Madaio, Michael, additional, Madias, Nicolaos E., additional, Makrides, Victoria, additional, Manoharon, Anup, additional, Matsson, Pär, additional, Mitch, William E., additional, Moe, Orson W., additional, Molitoris, Bruce A., additional, Murer, Heini, additional, Nattie, Eugene, additional, Nielsen, Rikke, additional, Palmer, Biff F., additional, Preisig, Patricia A., additional, Quamme, Gary A., additional, Quarles, L. Darryl, additional, Rajapurkar, Mohan, additional, Remuzzi, Giuseppe, additional, Riccardi, Daniela, additional, Schaefer, Heidi, additional, Schelling, Jeffrey R., additional, Schlingmann, Karl P., additional, Schrier, Robert W., additional, Sedor, John R., additional, Segal, Yoav, additional, Seldin, Donald W., additional, Shah, Sudhir V., additional, Sharfuddin, Asif, additional, Somlo, Stefan, additional, Stewart, Andrew K., additional, Tebben, Peter J., additional, Torres, Vicente E., additional, Verrey, François, additional, James Walker, Robert, additional, Wenger, Roland H., additional, Worcester, Elaine, additional, Workeneh, Biruh T., additional, Wright, Ernest M., additional, Wysolmerski, John, additional, Yang, Sung-Sen, additional, Zatz, Roberto, additional, Ziyadeh, Fuad N., additional, and Zoja, Carla, additional

Published
2012
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29. Contributors

Author

ABBATE, MAURO, primary, ABRAHAMSON, DALE R., additional, ADAMCZAK, MARCIN, additional, ADROGUÉ, HORACIO J., additional, ALPER, SETH L., additional, ALPERN, ROBERT J., additional, ANDREOLI, THOMAS E., additional, APERIA, ANITA C., additional, BAILEY, MATTHEW A., additional, BATLLE, DANIEL, additional, BAUM, MICHEL, additional, BERNDT, THERESA J., additional, BEVENSEE, MARK O., additional, BIBER, JÜRG, additional, BICHET, DANIEL G., additional, BINDELS, RENÉ J.M., additional, BLANTZ, ROLAND C., additional, BORON, WALTER F., additional, BRATER, D. CRAIG, additional, BRIGGS, JOSEPHINE P., additional, BROWN, ALEX, additional, BRUNSKILL, NIGEL J., additional, BURCKHARDT, GERHARD, additional, BURNSTOCK, GEOFFREY, additional, CANTLEY, LLOYD, additional, CAO, CHUNHUA, additional, CAPASSO, GIOVAMBATTISTA, additional, CAPLAN, MICHAEL J., additional, CARROLL, HUGH J., additional, CHAN, LAURENCE, additional, CHUNG-PARK, MOONJA, additional, COE, FREDRIC L., additional, COFFMAN, THOMAS M., additional, COMPER, WAYNE D., additional, CONRAD, KIRK P., additional, CROWLEY, STEVEN D., additional, CURTHOYS, NORMAN P., additional, CUTILLAS, PEDRO R., additional, DANOFF, THEODORE M., additional, DEBNAM, EDWARD S., additional, DIMKE, HENRIK, additional, DOUCET, ALAIN, additional, DUBEY, RAGHVENDRA K., additional, DUSSO, ADRIANA, additional, ECKARDT, KAI-UWE, additional, ELLISON, DAVID H., additional, ENDOU, HITOSHI, additional, ENDRE, ZOLTÁN HUBA, additional, EPSTEIN, FRANKLIN H., additional, EVAN, ANDREW, additional, FALK, RONALD J., additional, FARBAKHSH, KAMBIZ, additional, FERRERI, NICHOLAS R., additional, FONG, PEYING, additional, FONTELES, MANASSES CLAUDINO, additional, FORSTER, IAN, additional, FORTE, LEONARD RALPH, additional, FRANCH, HAROLD A., additional, FRASSETTO, LYNDA A., additional, FRIEDMAN, PETER A., additional, FRØKLÆR, JØRGEN, additional, GEIBEL, JOHN P., additional, GEKLE, MICHAEL, additional, GIEBISCH, GERHARD, additional, GINÈS, PERE, additional, GOLDSTEIN, STEVE A.N., additional, GORAL, SIMIN, additional, GRIFFIN, SIAN V., additional, GUGGINO, WILLIAM B., additional, GUISE, THERESA A., additional, GURLEY, SUSAN B., additional, HALL, STEPHEN D., additional, HALPERIN, MITCHELL L., additional, HAMM, L. LEE, additional, HEBERT, STEVEN C., additional, HEDIGER, MATTHIAS A., additional, HELDERMAN, J. HAROLD, additional, HENRICH, WILLIAM L., additional, HERAS-HERZIG, AILLEEN, additional, HERNANDO, NATI, additional, HOENDEROP, JOOST G.J., additional, HOLTBÄCK, ULLA, additional, HORISBERGER, JEAN-DANIEL, additional, HUMMLER, EDITH, additional, HUNLEY, TRACY E., additional, JACKSON, EDWIN K., additional, JENNETTE, J. CHARLES, additional, JOHNS, EDWARD J., additional, JOHNSON, JOHN P., additional, KAISSLING, BRIGITTE, additional, KAMEL, KAMEL S., additional, KARUMANCHI, S. ANANTH, additional, KASHTAN, CLIFFORD E., additional, KASISKE, BERTRAM L., additional, KATZ, ADRIAN I., additional, KING, BRIAN F., additional, KLAHR, SAULO, additional, KLEYMAN, THOMAS R., additional, KOEPSELL, HERMANN, additional, KON, VALENTINA, additional, KONRAD, MARTIN, additional, KOPP, ULLA C., additional, KRAPF, RETO, additional, KRIZ, WILHELM, additional, KUMAR, RAJIV, additional, KURSCHAT, CHRISTINE E., additional, KURTZ, ARMIN, additional, KWON, TAE-HWAN, additional, LANDOWSKI, CHRISTOPHER P., additional, LANGONE, ANTHONY J., additional, LANG, FLORIAN, additional, LAYTON, HAROLD E., additional, LE, THU H., additional, LEVY, DANIEL I., additional, LIN, SHIH-HUA, additional, LINDHEIMER, MARSHALL D., additional, LU, CHRISTOPHER Y., additional, MADAIO, MICHAEL P., additional, MADIAS, NICOLAOS E., additional, MALNIC, GERHARD, additional, MATLIN, KARL S., additional, McCLELLAN, WILLIAM C., additional, MCGIFF, JOHN C., additional, MICHEL, C. CHARLES, additional, MINER, JEFFREY H., additional, MITCH, WILLIAM E., additional, MIYAZAKI, HIROKI, additional, MOE, ORSON W., additional, MOLITORIS, BRUCE A., additional, MORRIS, R. CURTIS, additional, MUJAIS, SALIM K., additional, MURER, HEINI, additional, MUTO, SHIGEAKI, additional, NATTIE, EUGENE, additional, NEILSON, ERIC G., additional, NIELSEN, SØREN, additional, NIGAM, SANJAY K., additional, NOGUEIRA, JOSEPH M., additional, OH, MAN S., additional, OKUSA, MARK D., additional, OSICKA, TANYA M., additional, PALLONE, THOMAS L., additional, PALMER, BIFF F., additional, PALMER, LAWRENCE G., additional, PARKER, MARK D., additional, PARKS, JOAN H., additional, PREISIG, PATRICIA A., additional, QUAMME, GARY A., additional, QUARLES, L. DARRYL, additional, QUIGLEY, RAYMOND, additional, REEVES, W. BRIAN, additional, REMUZZI, GIUSEPPE, additional, REUSS, LUIS, additional, RICCARDI, DANIELA, additional, RINGHOFER, BRIAN, additional, RITZ, EBERHARD, additional, RIVARD, CHRISTOPHER J., additional, ROBERTSON, GARY L., additional, ROSA, ROBERT M., additional, ROSSIER, BERNARD C., additional, RUSSO, LEILEATA M., additional, SACKIN, HENRY, additional, SAKURAI, HIROYUKI, additional, SANDS, JEFF M., additional, SATLIN, LISA M., additional, SCHAEFER, HEIDI, additional, SCHELLING, JEFFREY R., additional, SCHILD, LAURENT, additional, SCHLINGMANN, KARL P., additional, SCHNERMANN, JÜRGEN B., additional, SCHRIER, ROBERT W., additional, SEBASTIAN, ANTHONY, additional, SEDOR, JOHN R., additional, SEGAL, YOAV, additional, SEKINE, TAKASHI, additional, SELDIN, DONALD W., additional, SENITKO, MARTIN, additional, SHAH, MALATHI, additional, SHAH, SUDHIR V., additional, SHANKLAND, STUART J., additional, SHARFUDDIN, ASIF A., additional, SHARMA, KUMAR, additional, SHENG, SHAOHU, additional, SHIRLEY, DAVID G., additional, SILBERNAGL, STEFAN, additional, SILVER, STEPHEN M., additional, SILVERMAN, MEL, additional, SLATOPOLSKY, EDUARDO, additional, SOMLO, STEFAN, additional, STERNS, RICHARD H., additional, STEWART, ANDREW K., additional, SUZUKI, YOSHIRO, additional, TEBBEN, PETER J., additional, THOMSON, SCOTT C., additional, TORRES, VICENTE E., additional, UNWIN, ROBERT J., additional, VERREY, FRANÇOIS, additional, VESELY, DAVID L., additional, WAGNER, CARSTEN A., additional, WALDMAN, MERYL, additional, WALKER, ROBERT JAMES, additional, WANG, WEI, additional, WANG, WEN-HUI, additional, WANG, YINGHONG, additional, WEINSTEIN, ALAN M., additional, WELLING, PAUL A., additional, WOLF, GUNTER, additional, WORCESTER, ELAINE, additional, ZIYADEH, FUAD N., additional, and ZOJA, CARLA, additional

Published
2008
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31. Impact of Social Media on Self-Referral Patterns for Living Kidney Donation

Author

DuBray, Bernard J., primary, Shawar, Saed H., additional, Rega, Scott A., additional, Smith, Kristin M., additional, Centanni, Kaylin M., additional, Warmke, Kara, additional, Concepcion, Beatrice P., additional, Edwards, Gretchen C., additional, Schaefer, Heidi M., additional, Feurer, Irene D., additional, and Forbes, Rachel C., additional

Published
2020
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32. Care of international living kidney donor candidates in the United States: A survey of contemporary experience, practice, and challenges

Author

Lentine, Krista L., primary, Motter, Jennifer D., additional, Henderson, Macey L., additional, Hays, Rebecca E, additional, Shukhman, Ellen, additional, Hunt, Julia, additional, Al Ammary, Fawaz, additional, Kumar, Vineeta, additional, LaPointe Rudow, Dianne, additional, Van Pilsum Rasmussen, Sarah E., additional, Nishio‐Lucar, Angie G., additional, Schaefer, Heidi M., additional, Cooper, Matthew, additional, and Mandelbrot, Didier A., additional

Published
2020
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34. Evaluation and care of international living kidney donor candidates: Strategies for addressing common considerations and challenges

Author

Shukhman, Ellen, primary, Hunt, Julia, additional, LaPointe‐Rudow, Dianne, additional, Mandelbrot, Didier, additional, Hays, Rebecca E., additional, Kumar, Vineeta, additional, Schaefer, Heidi, additional, Al Ammary, Fawaz, additional, Henderson, Macey L., additional, Nishio‐Lucar, Angie, additional, Cooper, Matthew, additional, and Lentine, Krista L., additional

Published
2020
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40. HMG-CoA reductase inhibitors in kidney transplant recipients receiving tacrolimus: statins not associated with improved patient or graft survival

Author

Schaefer Heidi, Basu Amit, Tan Henkie, Johnston James, McCauley Jerry, Shapiro Ron, Wu Christine M, Younas Nizar, Smetanka Cynthia, Winkelmayer Wolfgang C, and Unruh Mark

Subjects
Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract Background The beneficial effects of early statin use in kidney transplant recipients, especially those on tacrolimus-based immunosuppression, are not well established. We evaluated the predictors of statin use following kidney transplantation and examined its association with patient and allograft survival. Methods We examined 615 consecutive patients who underwent kidney transplant at our institution between January 1998 and January 2002. Statin use was assessed at baseline and 3, 6, 9, and 12 months following kidney transplant. Patients were followed for allograft and patient survival. Results 36% of the 615 kidney transplant recipients were treated with statin treatment. Statin use increased over the course of the study period. Older age, elevated body mass index, higher triglyceride levels, hypercholesterolemia, diabetes, history of myocardial infarction were associated with higher rates of statin use; elevated alkaline phosphatase levels and CMV IgG seropositivity were associated with less statin use. Older age, elevated BMI and hypercholesterolemia remained significant predictors of increased statin use after accounting for covariates using multiple regression. The early use of statins was not associated with improvements in unadjusted patient survival [HR 0.99; 95%CI 0.72-1.37] or graft survival [HR 0.97; 95% CI 0.76-1.24]. The risks of death and graft survival were not consistently reduced with exposure to statin using either adjusted models or propensity scores in Cox Proportional Hazards models. Conclusions In a kidney transplant population primarily receiving tacrolimus-based immunosuppression, early statin use was not associated with significantly improved graft or patient survival.

Published
2010
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41. A randomized, placebo-controlled phase I trial of live, attenuated herpes zoster vaccine in subjects with end-stage renal disease immunized prior to renal transplantation

Author

Miller, Geraldine, primary, Schaefer, Heidi, additional, Yoder, Sandra, additional, Miller, Rachel, additional, Winokur, Patricia, additional, Kotloff, Karen, additional, Klassen, David, additional, Wierzbicki, Michael, additional, Amegashie, Cyrille, additional, and Edwards, Kathryn, additional

Published
2018
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45. Novel Once-Daily Extended-Release Tacrolimus Versus Twice-Daily Tacrolimus in De Novo Kidney Transplant Recipients: Two-Year Results of Phase 3, Double-Blind, Randomized Trial

Author

Rostaing, Lionel, primary, Bunnapradist, Suphamai, additional, Grinyó, Josep M., additional, Ciechanowski, Kazimierz, additional, Denny, Jason E., additional, Silva, Helio Tedesco, additional, Budde, Klemens, additional, Kulkarni, Sanjay, additional, Hricik, Donald, additional, Bresnahan, Barbara A., additional, El-Sabrout, Rafik A., additional, Chan, Laurence K., additional, Ciancio, Gaetano, additional, El-Ghoroury, Mohamed A., additional, Goldstein, Michael J., additional, Gaston, Robert S., additional, Gohh, Reginald Y., additional, Killackey, Mary T., additional, King, Anne, additional, Knight, Richard J., additional, Kore, Arputharaj H., additional, Sudan, Debra L., additional, Chapochnick Friedmann, Javier, additional, Mulgaonkar, Shamkant P., additional, Nolan, Charles, additional, Pankewycz, Oleh G., additional, Pirsch, John D., additional, Schaefer, Heidi M., additional, Steinberg, Steven M., additional, Gelb, Bruce E., additional, True, Karin A., additional, West-Thielke, Patricia M., additional, Waybill, Mary M., additional, Wolf, Joshua H., additional, Ketel, Beverley L., additional, Harland, Robert C., additional, Shihab, Fuad S., additional, Cassuto, Elisabeth, additional, Le Meur, Yannick, additional, Rostaing, Lionel, additional, Mariat, Christophe, additional, Grinyó, Josep Maria, additional, Puig, Jose, additional, Seron, Daniel, additional, Tisone, Giuseppe, additional, Foroncewicz, Bartosz, additional, Wlodarczyk, Zbigniew, additional, Witzke, Oliver, additional, Mondragon, Guillermo A., additional, Mancilla Urrea, Eduardo, additional, Alberu Gomez, Josefina, additional, Reyes Acevedo, Rafael, additional, Rial, Maria del Carmen, additional, Novoa, Pablo A., additional, Silva, Helio T., additional, Garcia, Valter D., additional, Carvalho, Deise D., additional, Santamaria Saber, Luciana T., additional, Contieri, Fabiana L., additional, Bastos, Marcos G., additional, Manfro, Roberto C., additional, Kanellis, John, additional, Eris, Josette, additional, O’Connell, Philip, additional, Hughes, Peter, additional, Russ, Graeme, additional, Pidgeon, Grant B., additional, Dittmer, Ian D., additional, Kee, Terence, additional, Vathsala, Anantharaman, additional, Naumovic, Radomir, additional, Mitic, Igor, additional, and Parmjeet, Randhawa, additional

Published
2016
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