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7 results on '"Schacht, Simon R."'

1. The effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults: A randomized controlled trial

Author

Mertz, Kenneth H, primary, Reitelseder, Søren, additional, Bechshoeft, Rasmus, additional, Bulow, Jacob, additional, Højfeldt, Grith, additional, Jensen, Mikkel, additional, Schacht, Simon R, additional, Lind, Mads Vendelbo, additional, Rasmussen, Morten A, additional, Mikkelsen, Ulla R, additional, Tetens, Inge, additional, Engelsen, Søren B, additional, Nielsen, Dennis S, additional, Jespersen, Astrid P, additional, and Holm, Lars, additional

Published
2021
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3. Physical fitness in community-dwelling older adults is linked to dietary intake, gut microbiota, and metabolomic signatures

Author

Castro-Mejia, Josué L., Khakimov, Bekzod, Krych, Lukasz, Bülow, Jacob, Bechshøft, Rasmus L., Højfeldt, Grith, Mertz, Kenneth H., Garne, Eva Stahl, Schacht, Simon R., Ahmad, Hajar F., Kot, Witold, Hansen, Lars H., Perez-Cueto, Federico J. A., Lind, Mads V., Lassen, Aske J., Tetens, Inge, Jensen, Tenna, Reitelseder, Søren, Jespersen, Astrid P., Holm, Lars, Engelsen, Søren B., Nielsen, Dennis S., Castro-Mejia, Josué L., Khakimov, Bekzod, Krych, Lukasz, Bülow, Jacob, Bechshøft, Rasmus L., Højfeldt, Grith, Mertz, Kenneth H., Garne, Eva Stahl, Schacht, Simon R., Ahmad, Hajar F., Kot, Witold, Hansen, Lars H., Perez-Cueto, Federico J. A., Lind, Mads V., Lassen, Aske J., Tetens, Inge, Jensen, Tenna, Reitelseder, Søren, Jespersen, Astrid P., Holm, Lars, Engelsen, Søren B., and Nielsen, Dennis S.

Abstract

When humans age, changes in body composition arise along with lifestyle-associated disorders influencing fitness and physical decline. Here we provide a comprehensive view of dietary intake, physical activity, gut microbiota (GM), and host metabolome in relation to physical fitness of 207 community-dwelling subjects aged +65 years. Stratification on anthropometric/body composition/physical performance measurements (ABPm) variables identified two phenotypes (high/low-fitness) clearly linked to dietary intake, physical activity, GM, and host metabolome patterns. Strikingly, despite a higher energy intake high-fitness subjects were characterized by leaner bodies and lower fasting proinsulin-C-peptide/blood glucose levels in a mechanism likely driven by higher dietary fiber intake, physical activity and increased abundance of Bifidobacteriales and Clostridiales species in GM and associated metabolites (i.e., enterolactone). These factors explained 50.1% of the individual variation in physical fitness. We propose that targeting dietary strategies for modulation of GM and host metabolome interactions may allow establishing therapeutic approaches to delay and possibly revert comorbidities of aging.

Published
2020

4. Daily Protein and Energy Intake Are Not Associated with Muscle Mass and Physical Function in Healthy Older Individuals—A Cross-Sectional Study

Author

Højfeldt, Grith, primary, Nishimura, Yusuke, additional, Mertz, Kenneth, additional, Schacht, Simon R., additional, Lindberg, Jonas, additional, Jensen, Mikkel, additional, Hjulmand, Morten, additional, Lind, Mads Vendelbo, additional, Jensen, Tenna, additional, Jespersen, Astrid Pernille, additional, Reitelseder, Soren, additional, Tetens, Inge, additional, and Holm, Lars, additional

Published
2020
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5. Effects of Prolonged Whey Protein Supplementation and Resistance Training on Biomarkers of Vitamin B12 Status: A 1-Year Randomized Intervention in Healthy Older Adults (the CALM Study)

Author

Greibe, Eva, primary, Reitelseder, Søren, additional, Bechshøft, Rasmus L., additional, Bülow, Jacob, additional, Højfeldt, Grith W., additional, Schacht, Simon R., additional, Knudsen, Mads L., additional, Tetens, Inge, additional, Ostenfeld, Marie S., additional, Mikkelsen, Ulla R., additional, Heegaard, Christian W., additional, Nexo, Ebba, additional, and Holm, Lars, additional

Published
2020
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6. Physical fitness in community‐dwelling older adults is linked to dietary intake, gut microbiota, and metabolomic signatures

Author

Castro‐Mejía, Josué L., primary, Khakimov, Bekzod, additional, Krych, Łukasz, additional, Bülow, Jacob, additional, Bechshøft, Rasmus L., additional, Højfeldt, Grith, additional, Mertz, Kenneth H., additional, Garne, Eva Stahl, additional, Schacht, Simon R., additional, Ahmad, Hajar F., additional, Kot, Witold, additional, Hansen, Lars H., additional, Perez‐Cueto, Federico J. A., additional, Lind, Mads V., additional, Lassen, Aske J., additional, Tetens, Inge, additional, Jensen, Tenna, additional, Reitelseder, Søren, additional, Jespersen, Astrid P., additional, Holm, Lars, additional, Engelsen, Søren B., additional, and Nielsen, Dennis S., additional

Published
2020
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7. Physical fitness in community dwelling older adults is linked to dietary intake, gut microbiota and metabolomic signatures

Author

Castro-Mejía, Josué L., primary, Khakimov, Bekzod, additional, Krych, Łukasz, additional, Bülow, Jacob, additional, Bechshøft, Rasmus L., additional, Højfeldt, Grith, additional, Mertz, Kenneth H., additional, Garne, Eva Stahl, additional, Schacht, Simon R., additional, Ahmad, Hajar F., additional, Kot, Witold, additional, Hansen, Lars H., additional, Perez-Cueto, Federico J. A., additional, Lind, Mads V., additional, Lassen, Aske J., additional, Tetens, Inge, additional, Jensen, Tenna, additional, Reitelseder, Søren, additional, Jespersen, Astrid P., additional, Holm, Lars, additional, Engelsen, Søren B., additional, and Nielsen, Dennis S., additional

Published
2019
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