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2. Vaccine effectiveness against severe COVID-19 during the Omicron wave in Germany: results from the COViK study

Author

Stoliaroff-Pepin, Anna, Peine, Caroline, Herath, Tim, Lachmann, Johannes, Hellenbrand, Wiebke, Perriat, Delphine, Dörre, Achim, Nitsche, Andreas, Michel, Janine, Grossegesse, Marica, Hofmann, Natalie, Rinner, Thomas, Kohl, Claudia, Brinkmann, Annika, Meyer, Tanja, Stern, Daniel, Treindl, Fridolin, Dorner, Brigitte G., Hein, Sascha, Werel, Laura, Hildt, Eberhard, Gläser, Sven, Schühlen, Helmut, Isner, Caroline, Peric, Alexander, Ghouzi, Ammar, Reichardt, Annette, Janneck, Matthias, Lock, Guntram, Huster, Dominik, Grünewald, Thomas, Schaade, Lars, Wichmann, Ole, and Harder, Thomas

Published
2023
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3. A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity

Author

Stern, Daniel, Meyer, Tanja C., Treindl, Fridolin, Mages, Hans Werner, Krüger, Maren, Skiba, Martin, Krüger, Jan Philipp, Zobel, Christian M., Schreiner, Maximilian, Grossegesse, Marica, Rinner, Thomas, Peine, Caroline, Stoliaroff-Pépin, Anna, Harder, Thomas, Hofmann, Natalie, Michel, Janine, Nitsche, Andreas, Stahlberg, Silke, Kneuer, Antje, Sandoni, Anna, Kubisch, Ulrike, Schlaud, Martin, Mankertz, Annette, Schwarz, Tatjana, Corman, Victor M., Müller, Marcel A., Drosten, Christian, de la Rosa, Kathrin, Schaade, Lars, Dorner, Martin B., and Dorner, Brigitte G.

Published
2023
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5. Nationally representative results on SARS-CoV-2 seroprevalence and testing in Germany at the end of 2020

Author

Neuhauser, Hannelore, Rosario, Angelika Schaffrath, Butschalowsky, Hans, Haller, Sebastian, Hoebel, Jens, Michel, Janine, Nitsche, Andreas, Poethko-Müller, Christina, Prütz, Franziska, Schlaud, Martin, Steinhauer, Hans W., Wilking, Hendrik, Wieler, Lothar H., Schaade, Lars, Liebig, Stefan, Gößwald, Antje, Grabka, Markus M., Zinn, Sabine, and Ziese, Thomas

Published
2022
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16. Socioeconomic Differences in SARS-CoV-2 Infection and Vaccination in Germany: A Seroepidemiological Study After One Year of COVID-19 Vaccination Campaign

Author

Bartig, Susanne, primary, Beese, Florian, additional, Wachtler, Benjamin, additional, Grabka, Markus M., additional, Mercuri, Elisabetta, additional, Schmid, Lorenz, additional, Schmid-Küpke, Nora Katharina, additional, Schranz, Madlen, additional, Goßner, Laura, additional, Niehues, Wenke, additional, Zinn, Sabine, additional, Poethko-Müller, Christina, additional, Schaade, Lars, additional, Hövener, Claudia, additional, Gößwald, Antje, additional, and Hoebel, Jens, additional

Published
2023
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17. Sozioökonomische Unterschiede im SARS-CoV-2-Infektions-, Impf- und Serostatus nach einem Jahr COVID-19-Impfkampagne in Deutschland

Author

Beese, Florian, additional, Bartig, Susanne, additional, Wachtler, Benjamin, additional, Grabka, Markus M., additional, Mercuri, Elisabetta, additional, Schmid, Lorenz, additional, Schmid-Küpke, Nora Katharina, additional, Schranz, Madlen, additional, Goßner, Laura, additional, Niehues, Wenke, additional, Zinn, Sabine, additional, Poethko-Mueller, Christina, additional, Schaade, Lars, additional, Hövener, Claudia, additional, Gößwald, Antje, additional, and Hoebel, Jens, additional

Published
2023
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18. Gemeinsam können wir den Auswirkungen des Klimawandels begegnen

Author

Adrian, Gerhard, Dietrich, Martin, Esser, Birgit, Hensel, Andreas, Isermeyer, Folkhard, Messner, Dirk, Mettenleiter, Thomas C., Paulini, Inge, Riewenherm, Sabine, Schaade, Lars, Tiesler, Ralph, and Wieler, Lothar H.

Subjects
ddc:610, 610 Medizin und Gesundheit
Published
2023

19. A large travel-associated outbreak of iatrogenic botulism in four European countries following intragastric botulinum neurotoxin injections for weight reduction, Türkiye, February to March 2023

Author

Dorner, Martin Bernhard, primary, Wilking, Hendrik, additional, Skiba, Martin, additional, Wilk, Laura, additional, Steinberg, Maximilian, additional, Worbs, Sylvia, additional, Çeken, Sabahat, additional, Kaygusuz, Sedat, additional, Simon, Stéphanie, additional, Becher, François, additional, Mikolajewska, Agata, additional, Kornschober, Christian, additional, Bütler, Timo, additional, Jourdan-Da-Silva, Nathalie, additional, an der Heiden, Maria, additional, Schaade, Lars, additional, Stark, Klaus, additional, Dorner, Brigitte Gertrud, additional, and Frank, Christina, additional

Published
2023
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20. Direct comparison of clinical diagnostic sensitivity of saliva from buccal swabs versus combined oro-/nasopharyngeal swabs in the detection of SARS-CoV-2 B.1.1.529 Omicron

Author

Puyskens, Andreas, primary, Michel, Janine, additional, Stoliaroff-Pépin, Anna, additional, Bayram, Fatimanur, additional, Sesver, Akin, additional, Wichmann, Ole, additional, Harder, Thomas, additional, Schaade, Lars, additional, Nitsche, Andreas, additional, and Peine, Caroline, additional

Published
2023
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21. Performance of 20 rapid antigen detection tests to detect SARS-CoV-2 B.1.617.2 (Delta) and B.1.1.529 (Omicron) variants using a clinical specimen panel from January 2022, Berlin, Germany

Author

Puyskens, Andreas, primary, Bayram, Fatimanur, additional, Sesver, Akin, additional, Michel, Janine, additional, Krause, Eva, additional, Bourquain, Daniel, additional, Filomena, Angela, additional, Esser-Nobis, Katharina, additional, Steffanowski, Carla, additional, Nübling, C Micha, additional, Scheiblauer, Heinrich, additional, Schaade, Lars, additional, and Nitsche, Andreas, additional

Published
2023
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22. Estimating the share of SARS-CoV-2-immunologically naïve individuals in Germany up to June 2022

Author

Maier, Benjamin F., Rose, Annika H., Burdinski, Angelique, Klamser, Pascal, Neuhauser, Hannelore, Wichmann, Ole, Schaade, Lars, Wieler, Lothar H., Brockmann, Dirk, Maier, Benjamin F., Rose, Annika H., Burdinski, Angelique, Klamser, Pascal, Neuhauser, Hannelore, Wichmann, Ole, Schaade, Lars, Wieler, Lothar H., and Brockmann, Dirk

Abstract

After the winter of 2021/2022, the coronavirus disease 2019 (COVID-19) pandemic had reached a phase where a considerable number of people in Germany have been either infected with a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant, vaccinated or both, the full extent of which was difficult to estimate, however, because infection counts suffer from under-reporting, and the overlap between the vaccinated and recovered subpopulations is unknown. Yet, reliable estimates regarding population-wide susceptibility were of considerable interest: Since both previous infection and vaccination reduce the risk of severe disease, a low share of immunologically naïve individuals lowers the probability of further severe outbreaks, given that emerging variants do not escape the acquired susceptibility reduction. Here, we estimate the share of immunologically naïve individuals by age group for each of the sixteen German federal states by integrating an infectious-disease model based on weekly incidences of SARS-CoV-2 infections in the national surveillance system and vaccine uptake, as well as assumptions regarding under-ascertainment. We estimate a median share of 5.6% of individuals in the German population have neither been in contact with vaccine nor any variant up to 31 May 2022 (quartile range [2.5%-8.5%]). For the adult population at higher risk of severe disease, this figure is reduced to 3.8% [1.6%-5.9%] for ages 18-59 and 2.1% [1.0%-3.4%] for ages 60 and above. However, estimates vary between German states mostly due to heterogeneous vaccine uptake. Excluding Omicron infections from the analysis, 16.3% [14.1%-17.9%] of the population in Germany, across all ages, are estimated to be immunologically naïve, highlighting the large impact the first two Omicron waves had until the beginning of summer in 2022. The method developed here might be useful for similar estimations in other countries or future outbreaks of other infectious diseases.

Published
2023

23. Together we can counter the effects of climate change

Author

Adrian, Gerhard, Dietrich, Martin, Esser, Birgit, Hensel, Andreas, Isermeyer, Folkhard, Messner, Dirk, Mettenleiter, Thomas C., Paulini, Inge, Riewenherm, Sabine, Schaade, Lars, Tiesler, Ralph, and Wieler, Lothar H.

Subjects
ddc:610, 610 Medizin und Gesundheit
Published
2023

24. Vaccine effectiveness against severe COVID-19 during the Omicron wave in Germany: Results from the COViK study

Author

Stoliaroff-Pepin, Anna, primary, Peine, Caroline, additional, Herath, Tim, additional, Lachmann, Johannes, additional, Hellenbrand, Wiebke, additional, Perriat, Delphine, additional, Dörre, Achim, additional, Nitsche, Andreas, additional, Michel, Janine, additional, Grossegesse, Marica, additional, Hofmann, Natalie, additional, Rinner, Thomas, additional, Kohl, Claudia, additional, Brinkmann, Annika, additional, Meyer, Tanja, additional, Stern, Daniel, additional, Treindl, Fridolin, additional, Dorner, Brigitte G., additional, Hein, Sascha, additional, Werel, Laura, additional, Hildt, Eberhard, additional, Gläser, Sven, additional, Schühlen, Helmut, additional, Isner, Caroline, additional, Peric, Alexander, additional, Ghouzi, Ammar, additional, Reichardt, Annette, additional, Janneck, Matthias, additional, Lock, Guntram, additional, Huster, Dominik, additional, Grünewald, Thomas, additional, Schaade, Lars, additional, Wichmann, Ole, additional, and Harder, Thomas, additional

Published
2023
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25. First cross-border outbreak of foodborne botulism in the European Union associated with the consumption of commercial dried roach (Rutilus rutilus)

Author

Hendrickx, David, primary, Varela Martínez, Carmen, additional, Contzen, Matthias, additional, Wagner-Wiening, Christiane, additional, Janke, Karl-Heinz, additional, Hernando Jiménez, Pablo, additional, Massing, Susanne, additional, Pichler, Jeanette, additional, Tichaczek-Dischinger, Petra, additional, Burckhardt, Florian, additional, Stark, Klaus, additional, Katz, Katharina, additional, Jurke, Annette, additional, Thole, Sebastian, additional, Carbó, Rosa, additional, del Pobil Ferré, Mariam Pascual, additional, Nieto, Milagros, additional, Zamora, María Jesús, additional, Sisó, Ana, additional, Pallares García, Pilar, additional, Valdezate, Sylvia, additional, Schaade, Lars, additional, Worbs, Sylvia, additional, Dorner, Brigitte Gertrud, additional, Frank, Christina, additional, and Dorner, Martin Bernhard, additional

Published
2023
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26. Effectiveness of vaccines in preventing hospitalization due to COVID-19: A multicenter hospital-based case-control study, Germany, June 2021 to January 2022

Author

Stoliaroff-Pepin, Anna, primary, Peine, Caroline, additional, Herath, Tim, additional, Lachmann, Johannes, additional, Perriat, Delphine, additional, Dörre, Achim, additional, Nitsche, Andreas, additional, Michel, Janine, additional, Grossegesse, Marica, additional, Hofmann, Natalie, additional, Rinner, Thomas, additional, Kohl, Claudia, additional, Brinkmann, Annika, additional, Meyer, Tanja, additional, Dorner, Brigitte G., additional, Stern, Daniel, additional, Treindl, Fridolin, additional, Hein, Sascha, additional, Werel, Laura, additional, Hildt, Eberhard, additional, Gläser, Sven, additional, Schühlen, Helmut, additional, Isner, Caroline, additional, Peric, Alexander, additional, Ghouzi, Ammar, additional, Reichardt, Annette, additional, Janneck, Matthias, additional, Lock, Guntram, additional, Schaade, Lars, additional, Wichmann, Ole, additional, and Harder, Thomas, additional

Published
2023
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28. Case Study – Germany

Author

Uhlenhaut, Christine, Schaade, Lars, Finke, Ernst-Jürgen, Hunger, Iris, editor, Radosavljevic, Vladan, editor, Belojevic, Goran, editor, and Rotz, Lisa D., editor

Published
2013
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35. COVID-19-Pandemie: Surveillance und Studien des Robert Koch-Instituts zur Lage- und Maßnahmenbewertung

Author

Antao, Esther-Mario, Jung-Sedzik, Tanja, Buda, Silke, Haas, Walter, Diercke, Michaela, Schumacher, Jakob, Hamouda, Osamah, Schaade, Lars, and Wieler, Lothar

Subjects
Surveillance, SARS-CoV-2, Pandemie, COVID-19, Lagebewertung, ddc:610, 610 Medizin und Gesundheit
Abstract

Als nationales Public-Health-Institut überwacht und analysiert das RKI die Verbreitung übertragbarer und nicht übertragbarer Krankheiten in Deutschland. Im Rahmen der COVID-19-Pandemie wurden die bestehenden Surveillance-Systeme zur Überwachung akuter respiratorischer Atemwegserkrankungen angepasst und erweitert und durch wissenschaftliche Studien ergänzt. Der im Epidemiologischen Bulletin 29/2022 veröffentlichte Beitrag gibt eine Übersicht über die in der COVID-19-Pandemie besonders relevanten Informations- und Datenquellen, die der epidemiologischen Lagebewertung sowie der Planung, Durchführung und Bewertung von Präventions- und Bekämpfungsmaßnahmen dienen.

Published
2022

36. Weltweiter Ausbruch von Affenpocken - Situationsbeschreibung des Robert Koch-Instituts für Deutschland, Datenstand 14.07.2022

Author

Falkenhorst, Gerhard, Jansen, Klaus, Lachmann, Raskit, Koppe, Uwe, Selb, Regina, Steffen, Gyde, Schaade, Lars, Nitsche, Andreas, Michel, Janine, and Frank, Christina

Subjects
Public Health-Maßnahmen, MPX, ddc:610, Ausbruch, Orthopockenviren, 610 Medizin und Gesundheit, Affenpocken
Abstract

Im Mai 2022 häuften sich nicht-reiseassoziierte Fälle von Affenpocken. Seitdem hat sich ein weltweiter Ausbruch mit über 11.000 Fällen in 69 Ländern entwickelt, von denen rund 80 % in Europa gemeldet wurden. In Deutschland sind 1.790 Fälle bekannt (Datenstand: 14.07.2022), das Ausbruchsgeschehen konzentriert sich hierbei hauptsächlich auf große Städte. Bis Kalenderwoche 25/2022 ist die Zahl der gemeldeten Fälle stark gestiegen, seitdem hat sich der Anstieg abgeflacht. Der im Epidemiologischen Bulletin 29/2022 veröffentlichte Bericht fasst die epidemiologische Lage des Ausbruchs und den Kenntnisstand zu Symptomen und Übertragungswegen zusammen, gibt einen Überblick über die umgesetzten Public Health-Maßnahmen inklusive Kommunikations- und Vorsichtsmaßnahmen, Impfung, Diagnostik sowie laufende Studien und bietet einen Ausblick in die Zukunft.

Published
2022

37. Corona Monitoring Nationwide (RKI-SOEP-2): Seroepidemiological Study on the Spread of SARS-CoV-2 Across Germany

Author

Bartig, Susanne, primary, Brücker, Herbert, additional, Butschalowsky, Hans, additional, Danne, Christian, additional, Gößwald, Antje, additional, Goßner, Laura, additional, Grabka, Markus M., additional, Haller, Sebastian, additional, Hess, Doris, additional, Hey, Isabell, additional, Hoebel, Jens, additional, Jordan, Susanne, additional, Kubisch, Ulrike, additional, Niehues, Wenke, additional, Poethko-Mueller, Christina, additional, Priem, Maximilian, additional, Rother, Nina, additional, Schaade, Lars, additional, Schaffrath Rosario, Angelika, additional, Schlaud, Martin, additional, Siegert, Manuel, additional, Stahlberg, Silke, additional, Steinhauer, Hans W., additional, Tanis, Kerstin, additional, Torregroza, Sabrina, additional, Trübswetter, Parvati, additional, Wernitz, Jörg, additional, Wieler, Lothar H., additional, Wilking, Hendrik, additional, and Zinn, Sabine, additional

Published
2022
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38. Tod aus der Kanalisation

Author

Ritter, Klaus, Ritter, Susanne, Brandt, Claudia, Schaade, Lars, Geiss, Heinrich K., editor, Jacobs, Enno, editor, and Mack, Dietrich, editor

Published
2002
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40. Flecken und Knoten

Author

Brandt, Claudia, Schaade, Lars, Mager, Rolf, Ritter, Klaus, Geiss, Heinrich K., editor, Jacobs, Enno, editor, and Mack, Dietrich, editor

Published
2002
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41. Seroepidemiological study on the spread of SARS-CoV-2 in Germany: Study protocol of the ‘CORONA-MONITORING bundesweit’ study (RKI-SOEP study)

Author

Hoebel, Jens, Busch, Markus A., Grabka, Markus M., Zinn, Sabine, Allen, Jennifer, Gößwald, Antje, Wernitz, Jörg, Goebel, Jan, Steinhauer, Hans Walter, Siegers, Rainer, Schröder, Carsten, Kuttig, Tim, Butschalowsky, Hans, Schlaud, Martin, Schaffrath Rosario, Angelika, Brix, Jana, Rysina, Anna, Glemser, Axel, Neuhauser, Hannelore, Stahlberg, Silke, Kneuer, Antje, Hey, Isabell, Schaarschmidt, Jörg, Fiebig, Julia, Buttmann-Schweiger, Nina, Wilking, Hendrik, Michel, Janine, Nitsche, Andreas, Wieler, Lothar H., Schaade, Lars, Ziese, Thomas, Liebig, Stefan, Lampert, Thomas, Hoebel, Jens, Busch, Markus A., Grabka, Markus M., Zinn, Sabine, Allen, Jennifer, Gößwald, Antje, Wernitz, Jörg, Goebel, Jan, Steinhauer, Hans Walter, Siegers, Rainer, Schröder, Carsten, Kuttig, Tim, Butschalowsky, Hans, Schlaud, Martin, Schaffrath Rosario, Angelika, Brix, Jana, Rysina, Anna, Glemser, Axel, Neuhauser, Hannelore, Stahlberg, Silke, Kneuer, Antje, Hey, Isabell, Schaarschmidt, Jörg, Fiebig, Julia, Buttmann-Schweiger, Nina, Wilking, Hendrik, Michel, Janine, Nitsche, Andreas, Wieler, Lothar H., Schaade, Lars, Ziese, Thomas, Liebig, Stefan, and Lampert, Thomas

Abstract

The SARS-CoV-2 coronavirus has spread rapidly across Germany. Infections are likely to be under-recorded in the notification data from local health authorities on laboratory-confirmed cases since SARS-CoV-2 infections can proceed with few symptoms and then often remain undetected. Seroepidemiological studies allow the estimation of the proportion in the population that has been infected with SARS-CoV-2 (seroprevalence) as well as the extent of undetected infections. The ‘CORONA-MONITORING bundesweit’ study (RKI-SOEP study) collects biospecimens and interview data in a nationwide population sample drawn from the German Socio-Economic Panel (SOEP). Participants are sent materials to self-collect a dry blood sample of capillary blood from their finger and a swab sample from their mouth and nose, as well as a questionnaire. The samples returned are tested for SARS-CoV-2 IgG antibodies and SARS-CoV-2 RNA to identify past or present infections. The methods applied enable the identification of SARS-CoV-2 infections, including those that previously went undetected. In addition, by linking the data collected with available SOEP data, the study has the potential to investigate social and health-related differences in infection status. Thus, the study contributes to an improved understanding of the extent of the epidemic in Germany, as well as identification of target groups for infection protection.

Published
2022

42. Seroepidemiologische Studie zur bundesweiten Verbreitung von SARS-CoV-2 in Deutschland: Studienprotokoll von CORONA-MONITORING bundesweit (RKI-SOEP-Studie)

Author

Hoebel, Jens, Busch, Markus A., Grabka, Markus M., Zinn, Sabine, Allen, Jennifer, Gößwald, Antje, Wernitz, Jörg, Goebel, Jan, Steinhauer, Hans Walter, Siegers, Rainer, Schröder, Carsten, Kuttig, Tim, Butschalowsky, Hans, Schlaud, Martin, Schaffrath Rosario, Angelika, Brix, Jana, Rysina, Anna, Glemser, Axel, Neuhauser, Hannelore, Stahlberg, Silke, Kneuer, Antje, Hey, Isabell, Schaarschmidt, Jörg, Fiebig, Julia, Buttmann-Schweiger, Nina, Wilking, Hendrik, Michel, Janine, Nitsche, Andreas, Wieler, Lothar H., Schaade, Lars, Ziese, Thomas, Liebig, Stefan, Lampert, Thomas, Hoebel, Jens, Busch, Markus A., Grabka, Markus M., Zinn, Sabine, Allen, Jennifer, Gößwald, Antje, Wernitz, Jörg, Goebel, Jan, Steinhauer, Hans Walter, Siegers, Rainer, Schröder, Carsten, Kuttig, Tim, Butschalowsky, Hans, Schlaud, Martin, Schaffrath Rosario, Angelika, Brix, Jana, Rysina, Anna, Glemser, Axel, Neuhauser, Hannelore, Stahlberg, Silke, Kneuer, Antje, Hey, Isabell, Schaarschmidt, Jörg, Fiebig, Julia, Buttmann-Schweiger, Nina, Wilking, Hendrik, Michel, Janine, Nitsche, Andreas, Wieler, Lothar H., Schaade, Lars, Ziese, Thomas, Liebig, Stefan, and Lampert, Thomas

Abstract

Das Coronavirus SARS-CoV-2 hat sich in kurzer Zeit bundesweit ausgebreitet. In den Meldedaten der Gesundheitsämter zu laborbestätigten Infektionsfällen ist von einer Untererfassung des Infektionsgeschehens auszugehen, da Infektionen häufig unentdeckt bleiben, zum Beispiel weil sie symptomarm verlaufen. In seroepidemiologischen Studien kann der Bevölkerungsanteil mit durchgemachter SARS-CoV-2-Infektion (Seroprävalenz) wie auch der Umfang unentdeckter Infektionen abgeschätzt werden. In der Studie CORONA-MONITORING bundesweit (RKI-SOEP-Studie) werden Bioproben und Befragungsdaten in einer deutschlandweiten Bevölkerungsstichprobe des Sozio-oekonomischen Panels (SOEP) erhoben. Den Teilnehmenden werden Materialien zur selbstständigen Gewinnung einer Trockenblutprobe aus Kapillarblut des Fingers und einer Abstrichprobe aus Mund und Nase sowie ein Fragebogen postalisch zugesendet. Die zurückgesendeten Proben werden auf SARS-CoV-2-IgG-Antikörper und SARS-CoV-2-RNA zur Identifikation einer durchgemachten oder aktuellen Infektion untersucht. Die eingesetzten Methoden ermöglichen es, auch solche SARS-CoV-2-Infektionen zu erkennen, die bislang unentdeckt blieben. Durch die Verknüpfung mit bereits vorhandenen SOEP-Daten hat die Studie das Potenzial, auch soziale und gesundheitsbezogene Unterschiede im Infektionsstatus zu untersuchen. So kann die Studie zu einem verbesserten Verständnis des Ausmaßes der Epidemie in Deutschland wie auch zur Identifikation von Zielgruppen für den Infektionsschutz beitragen.

Published
2022

43. Corona Monitoring Nationwide (RKI-SOEP-2): Seroepidemiological Study on the Spread of SARS-CoV-2 Across Germany.

Author

Bartig, Susanne, Brücker, Herbert, Butschalowsky, Hans, Danne, Christian, Gößwald, Antje, Goßner, Laura, Grabka, Markus M., Haller, Sebastian, Hess, Doris, Hey, Isabell, Hoebel, Jens, Jordan, Susanne, Kubisch, Ulrike, Niehues, Wenke, Poethko-Mueller, Christina, Priem, Maximilian, Rother, Nina, Schaade, Lars, Schaffrath Rosario, Angelika, and Schlaud, Martin

Abstract

SARS-CoV-2, the coronavirus, spread across Germany within just a short period of time. Seroepidemiological studies are able to estimate the proportion of the population with antibodies against SARS-CoV-2 infection (seroprevalence) as well as the level of undetected infections, which are not captured in official figures. In the seroepidemiological study Corona Monitoring Nationwide (RKI-SOEP-2), biospecimens and interview data were collected in a nationwide population-based subsample of the Socio-Economic Panel (SOEP). By using laboratory-analyzed blood samples to detect antibodies to the SARS-CoV-2 virus, we were able to identify a history of vaccination or infection in study participants. By combining these results with survey data, we were able to identify groups within the population that are at increased risk of infection. By linking the RKI-SOEP-2 survey data with data from other waves of the SOEP survey, we will be able to examine the medium- to long-term impacts of the COVID-19 pandemic, including effects of long COVID, in diverse areas of life. Furthermore, the data provide insight into the population's willingness to be vaccinated as well as related attitudes and conditions. In sum, the RKI-SOEP-2 survey data offer a better understanding of the scope of the epidemic in Germany and can help in identifying target groups for infection control in the present and future pandemics. [ABSTRACT FROM AUTHOR]

Published
2023
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44. Investigating the zoonotic origin of the West African Ebola epidemic

Author

Marí Saéz, Almudena, Weiss, Sabrina, Nowak, Kathrin, Lapeyre, Vincent, Zimmermann, Fee, Düx, Ariane, Kühl, Hjalmar S, Kaba, Moussa, Regnaut, Sebastien, Merkel, Kevin, Sachse, Andreas, Thiesen, Ulla, Villányi, Lili, Boesch, Christophe, Dabrowski, Piotr W, Radonić, Aleksandar, Nitsche, Andreas, Leendertz, Siv Aina J, Petterson, Stefan, Becker, Stephan, Krähling, Verena, Couacy‐Hymann, Emmanuel, Akoua‐Koffi, Chantal, Weber, Natalie, Schaade, Lars, Fahr, Jakob, Borchert, Matthias, Gogarten, Jan F, Calvignac‐Spencer, Sébastien, and Leendertz, Fabian H

Published
2015
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45. Effectiveness of vaccines in preventing hospitalization due to COVID-19: A multicenter hospital-based case-control study, Germany, June 2021 to January 2022

Author

Stoliaroff-Pepin, Anna, primary, Peine, Caroline, additional, Herath, Tim, additional, Lachmann, Johannes, additional, Perriat, Delphine, additional, Dörre, Achim, additional, Nitsche, Andreas, additional, Michel, Janine, additional, Grossegesse, Marica, additional, Hofmann, Natalie, additional, Rinner, Thomas, additional, Kohl, Claudia, additional, Brinkmann, Annika, additional, Meyer, Tanja, additional, Dorner, Brigitte G., additional, Stern, Daniel, additional, Treindl, Fridolin, additional, Hein, Sascha, additional, Werel, Laura, additional, Hildt, Eberhard, additional, Gläser, Sven, additional, Schühlen, Helmut, additional, Isner, Caroline, additional, Peric, Alexander, additional, Ghouzi, Ammar, additional, Reichardt, Annette, additional, Janneck, Matthias, additional, Lock, Guntram, additional, Schaade, Lars, additional, Wichmann, Ole, additional, and Harder, Thomas, additional

Published
2022
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48. Soziale Ungleichheit und COVID-19 in Deutschland – Wo stehen wir in der vierten Pandemiewelle?

Author

Hoebel, Jens, Haller, Sebastian, Bartig, Susanne, Michalski, Niels, Marquis, Adine, Diercke, Michaela, Schmid-Küpke, Nora, Wichmann, Ole, Sarma, Navina, Schaade, Lars, and Hövener, Claudia

Subjects
Soziale Ungleichheit, Deprivation, sozioökonomisch benachteiligt, SARS-CoV-2, COVID-19, ddc:610, 610 Medizin und Gesundheit
Abstract

Für eine Vielzahl von Erkrankungen und Todesursachen ist zwischen der sozioökonomischen und gesundheitlichen Lage ein enger Zusammenhang nachgewiesen. Auch die Ausbreitungsmuster von SARS-CoV-2 über verschiedene soziale Gruppen werden seit Pandemiebeginn international und in Studien des RKI bundesweit untersucht. Im Beitrag werden die zentralen Ergebnisse zum aktuellen Stand zusammengefasst und um Daten aus der dritten und vierten Pandemiewelle ergänzt. Aus den dargestellten Befunden ergeben sich Hinweise auf Möglichkeiten, die Lücken im Infektionsschutz zu schließen.

Published
2022

49. RespiCoV: Simultaneous identification of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and 46 respiratory tract viruses and bacteria by amplicon-based Oxford-Nanopore MinION sequencing

Author

Brinkmann, Annika, primary, Uddin, Steven, additional, Ulm, Sophie-Luisa, additional, Pape, Katharina, additional, Förster, Sophie, additional, Enan, Khalid, additional, Nourlil, Jalal, additional, Krause, Eva, additional, Schaade, Lars, additional, Michel, Janine, additional, and Nitsche, Andreas, additional

Published
2022
Full Text
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50. Deep Time Course Proteomics of SARS-CoV- and SARS-CoV-2-Infected Human Lung Epithelial Cells (Calu-3) Reveals Strong Induction of Interferon-Stimulated Gene Expression by SARS-CoV-2 in Contrast to SARS-CoV

Author

Grossegesse, Marica, primary, Bourquain, Daniel, additional, Neumann, Markus, additional, Schaade, Lars, additional, Schulze, Jessica, additional, Mache, Christin, additional, Wolff, Thorsten, additional, Nitsche, Andreas, additional, and Doellinger, Joerg, additional

Published
2022
Full Text
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