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1. Play, PE, Paint, and Performance: What Gets Left behind When Teaching Academic Content in Kindergarten

Author

Vi-Nhuan Le, Diana Schaack, and Michael Gottfri

Abstract

There is currently a debate as to whether academic content at kindergarten crowds out time spent in creative arts, free play, and physical activity. Analyzing kindergarten teachers' reports of their instruction from the ECLS-K:2011, this study examined whether core academic content or advanced academic content in math or English language arts (ELA) displaces time spent in creative arts, indoor free play, and physical activity. The results suggested that neither core academic content nor advanced academic content in either subject displaced physical activity. More time spent on advanced math and advanced ELA was associated with more time spent on creative arts. However, teachers who reported spending more time on advanced math also reported spending less time on indoor free play.

Published
2024
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2. Radiofrequency balloon ablation: 1-year outcomes of the AURORA study

Author

My, Ilaria, Schmidt, Boris, Rottner, Laura, Tohoku, Shota, Lemoine, Marc, Schaack, David, Moser, Fabian, Urbanek, Lukas, Obergassel, Julius, Ismaili, Djemail, Hirokami, Jun, Kirchhof, Paulus, Plank, Karin, Reissmann, Bruno, Ouyang, Feifan, Rillig, Andreas, Chun, Julian, Metzner, Andreas, and Bordignon, Stefano

Published
2024
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6. When Quantum Fluctuations Meet Structural Instabilities: The Isotope- and Pressure-Induced Phase Transition in the Quantum Paraelectric NaOH

Author

Schaack, Sofiane, Mangaud, Etienne, Fallacara, Erika, Huppert, Simon, Depondt, Philippe, and Finocchi, Fabio

Subjects
Condensed Matter - Materials Science, Condensed Matter - Statistical Mechanics
Abstract

Anhydrous sodium hydroxide, a common and structurally simple compound, shows spectacular isotope effects: NaOD undergoes a first-order transition, which is absent in NaOH. By combining ab initio electronic structure calculations with path integrals, we show that NaOH is an unusual example of a quantum paraelectric: zero-point quantum fluctuations stretch the weak hydrogen bonds (HBs) until they become unstable and break. By strengthening HBs via isotope substitution or applied pressure, the system can be driven down to a broken-symmetry antiferroelectric phase. We also provide a simple quantitative criterion for HB breaking in layered crystals and show that nuclear quantum effects are crucial in paraelectric to ferroelectric transitions in hydrogen-bonded hydroxides.

Published
2023
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8. Long‐term follow‐up of patients treated with laser balloon for atrial fibrillation: A high volume center experience with the first‐ and second‐generation laser balloon

Author

Lukas Urbanek, Stefano Bordignon, Shota Tohoku, Jun Hirokami, Takahiko Nagase, Shaojie Chen, David Schaack, K. R. Julian Chun, and Boris Schmidt

Subjects
ablation, arrhythmia, atrial fibrillation, laser balloon, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Background Laser balloon (LB) pulmonary vein isolation (PVI) is an established ablation technique for atrial fibrillation (AF). We report long‐term follow‐up and procedural data of LB‐PVI and we compare the first and second LB generation. Methods Patients undergoing LB ablation with first‐ (LB1) or second‐generation LB (LB2) for AF were retrospectively enrolled and divided into two groups. Procedural endpoint was complete PVI. Clinical success was defined as no recurrence of AF/atrial tachycardia after a 90 days blanking period. Results 538 patients were included (age 66 ± 10 years, 58% paroxysmal AF), 427 in LB1 and 111 in LB2. 2079 PVs were targeted and 2073 (99.7%) were successfully isolated; 2027 (97.5%) using solely the LB. Additional touch‐up ablation was limited (46 PVs; 2.2%) with no difference between the groups. Procedural (LB1: 120 ± 33 minutes vs. LB2: 99 ± 22 min; p

Published
2024
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9. Characterizing Utilization and Outcomes of Digoxin Immune Fab for Digoxin Toxicity

Author

Sophia Sheikh, Taylor Munson, Gerard Garvan, Claire Layton, Dawn Sollee, Colleen Cowdery, Alexa Peterson, Lindsay Schaack Rothstein, Morgan Henson, Hayley Gartner, and Michael Ujhelyi

Subjects
Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441
Abstract

Abstract Background Digoxin is a widely prescribed drug for congestive heart failure and atrial fibrillation. Digoxin has a narrow therapeutic index and toxicity can develop quite easily. Digoxin immune fab (DIF) is an effective treatment for toxicity, however there are limited studies characterizing its impact on clinical outcomes in real-world clinical practice. Objectives The aim of this study was to identify factors and healthcare outcomes associated with digoxin immune fab (DIF) treatment in patients with confirmed/suspected digoxin toxicity. Methods An IRB-approved retrospective chart review of digoxin toxic patients (2011–2020) presenting at an academic healthcare system was conducted. Demographic and clinical data were collected. Patients were stratified by DIF treatment versus non-DIF treatment. DIF utilization patterns (appropriate, use when not indicated, or underutilized) were determined using pre-defined criteria. Severe digoxin toxicity was defined as having one or more of the following: mental status disturbances, antiarrhythmic therapy, acute renal impairment or dehydration, serum digoxin concentration (SDC) > 4 ng/mL, or serum K+ > 5 mEq/mL. Logistic multivariable regression analysis evaluated factors associated with DIF use. All statistical analyses were performed in R version 4.1. Results Data from 96 patients (non-DIF treated group = 49; DIF treated group = 47) were analyzed. DIF was used appropriately in 70 patients (73%), underutilized in 19 (20%), and administered to 7 (7%) patients when it was not indicated. Several clinical parameters differentiated the DIF from the non-DIF group (p

Published
2024
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11. Relationship between body mass index and cardiometabolic health in a multi-ethnic population: A project baseline health study

Author

Nishant P. Shah, Rong Lu, Francois Haddad, Scarlet Shore, Terry Schaack, Jessica Mega, Neha J. Pagidipati, Latha Palaniappan, Kenneth Mahaffey, Svati H. Shah, and Fatima Rodriguez

Subjects
Obesity, BMI, Project baseline health study, Diseases of the circulatory (Cardiovascular) system, RC666-701, Public aspects of medicine, RA1-1270
Abstract

Objective: Obesity is associated with a higher risk of cardiovascular disease. Understanding the associations between comprehensive health parameters and body mass index (BMI) may lead to targeted prevention efforts. Methods: Project Baseline Health Study (PBHS) participants were divided into six BMI categories: underweight (BMI 0, hypertension, diabetes, lower HDL-C, lower vitamin D, higher triglycerides, higher hsCRP, lower mean step counts, higher mean PHQ-9 scores, and higher mean GAD-7 scores. Conclusion: We identified associations of cardiometabolic and mental health characteristics with BMI, thereby providing a deeper understanding of cardiovascular health across BMI.

Published
2024
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14. Development and Evaluation of a Cost-effective IMU System for Gait Analysis: Comparison with Vicon and VideoPose3D Algorithms

Author

Wilhelm Nikolas, Micheler Carina M., Lang Jan J., Hinterwimmer Florian, Schaack Victor, Smits Ricardo, Haddadin Sami, and Burgkart Rainer

Subjects
imu, gait analysis, vicon, videopose3d, Medicine
Abstract

This study aimed to develop and evaluate a costeffective Inertial Measurement Unit (IMU) system for gait analysis, comparing its performance with the Vicon system and the VideoPose3D algorithm. The system comprises five calibrated sensors and a mobile app to measure lower body orientation during gait and stair climbing. Eight healthy participants were involved in the experiment, each performing ten repetitions to analyze hip and knee flexion angles. The IMU system demonstrated significantly lower mean square error than deep learning-based approaches and comparable results to the Vicon system, indicating its potential for clinical and research applications.

Published
2023
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15. Biomechanical Test Setup for the Investigation of Forehead Suture Techniques

Author

Micheler Carina M., Lang Jan J., Bäumlisberger Anja, Wachtel Nikolaus, Wilhelm Nikolas J., Schaack Victor G., Eisenhart-Rothe Rüdiger von, and Burgkart Rainer H. H.

Subjects
biomechanics, suture, forehead, tensile test, Medicine
Abstract

Wound healing can be delayed if the biomechanical stability of the wound closure is inadequate. Therefore, it is necessary to investigate different suturing techniques for their biomechanical stability. In this study, suturing techniques suitable for the forehead area were investigated. For this application, a special test setup was developed to simulate the curvature of the forehead and the corresponding physiological configuration. The average forehead curvature is 62.24 ± 4.11 mm in radius. To simulate this curvature, the skin specimens are subjected to tensile stress over the spherical surface using a standard uniaxial testing machine. For the evaluation, an automated evaluation tool for MATLAB was also developed. Three different suturing techniques (Straight, Lazy-S, Zigzag) were investigated and tested for their biomechanical stability. Of the three suturing techniques, the Zigzag suture proved to be the most stable with the highest stiffness of 44.23 ± 8.18 % and the highest final failure of 32.60 ± 4.95 % (relative to the control sample without incision). The study has shown that the test setup can be used to investigate different forehead suture techniques.

Published
2023
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17. Quantum driven proton diffusion in brucite-like minerals under high pressure

Author

Schaack, Sofiane, Depondt, Philippe, Huppert, Simon, and Finocchi, Fabio

Subjects
Condensed Matter - Materials Science
Abstract

We investigate the elementary steps at the microscopic level for proton diffusion in brucite under high pressure, which results from a complex interplay between two processes: the O-H reorientations motion around the $\mathbf c$ axis and O-H covalent bond dissociations. First-principle path-integral molecular dynamics simulations reveal that the increasing pressure tends to lock the former motion, while, in contrast, it activates the latter which is mainly triggered by nuclear quantum effects. These two competing effects therefore give rise to a pressure sweet spot for proton diffusion within the mineral. In brucite \ce{Mg(OH)2}, proton diffusion reaches a maximum for pressures close to 70GPa, while the structurally similar portlandite \ce{Ca(OH)2} never shows proton diffusion within the pressure range and time scale that we explored. We analyze the different behaviors of brucite and portlandite, which might constitute two prototypes for other minerals with the same structure.

Published
2020

18. To Stay or to Leave: Factors Shaping Early Childhood Teachers' Turnover and Retention Decisions

Author

Schaack, Diana D., Donovan, Courtney V., Adejumo, Tobiloba, and Ortega, Mari

Abstract

This qualitative study sought to understand whether there were difference in how early childhood education (ECE) teachers who stayed in or left their jobs interpreted their job demands and resources. It also sought to understand factors that shaped teachers' turnover and retention decisions. Twenty-six teachers who worked in subsidized ECE programs that blended multiple public funding sources were interviewed, 14 of whom stayed in their jobs and 12 of whom left their jobs. We found teachers' reasons for leaving or staying were complex and took into consideration workplace and family factors. Teachers who stayed tended to share the same job frustrations as those who left, namely a misalignment between job demands and resources, but those who stayed were more willing to engage creatively in solving workplace problems. Teachers who stayed placed greater value on professional development opportunities than teachers who left, and these key job rewards factored into retention decisions. Teachers who left often felt that lacking key job resources undermined their sense of competence at being an effective teacher and viewed the psychosocial workplace climate less favorably than teachers who stayed. For many teachers, the value they placed on different job rewards was influenced by family factors.

Published
2022
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22. Rapid Biodistribution of Fluorescent Outer-Membrane Vesicles from the Intestine to Distant Organs via the Blood in Mice

Author

Béatrice Schaack, Corinne Mercier, Maya Katby, Dalil Hannani, Julien Vollaire, Julie Suzanne Robert, Clément Caffaratti, Françoise Blanquet, Olivier Nicoud, Véronique Josserand, and David Laurin

Subjects
biodistribution, extracellular vesicles, miRFP713, outer membrane vesicles (OMVs), live imaging, microbiota, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract

A cell’s ability to secrete extracellular vesicles (EVs) for communication is present in all three domains of life. Notably, Gram-negative bacteria produce a specific type of EVs called outer membrane vesicles (OMVs). We previously observed the presence of OMVs in human blood, which could represent a means of communication from the microbiota to the host. Here, in order to investigate the possible translocation of OMVs from the intestine to other organs, the mouse was used as an animal model after OMVs administration. To achieve this, we first optimized the signal of OMVs containing the fluorescent protein miRFP713 associated with the outer membrane anchoring peptide OmpA by adding biliverdin, a fluorescence cofactor, to the cultures. The miRFP713-expressing OMVs produced in E. coli REL606 strain were then characterized according to their diameter and protein composition. Native- and miRFP713-expressing OMVs were found to produce homogenous populations of vesicles. Finally, in vivo and ex vivo fluorescence imaging was used to monitor the distribution of miRFP713-OMVs in mice in various organs whether by intravenous injection or oral gavage. The relative stability of the fluorescence signals up to 3 days post-injection/gavage paves the way to future studies investigating the OMV-based communication established between the different microbiotas and their host.

Published
2024
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23. Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks

Author

Katherine A. Amato, Luis A. Haddock, Katarina M. Braun, Victoria Meliopoulos, Brandi Livingston, Rebekah Honce, Grace A. Schaack, Emma Boehm, Christina A. Higgins, Gabrielle L. Barry, Katia Koelle, Stacey Schultz-Cherry, Thomas C. Friedrich, and Andrew Mehle

Subjects
Science
Abstract

Transmission of influenza A viruses (IAV) between hosts and replication within host impose genetic bottlenecks, constraining viral diversity and adaptation. Here, Amato et al. perform site-specific inoculation of barcoded IAV of ferrets and track viral diversity as infection spreads to the lower respiratory tract and conclude that narrow population bottlenecks are an important feature of the within-host infection dynamics.

Published
2022
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24. Pulsed Field Ablation for Atrial Fibrillation

Author

David Schaack, Boris Schmidt, Shota Tohoku, Stefano Bordignon, Lukas Urbanek, Ramin Ebrahimi, Jun Hirokami, Tolga Han Efe, Shaojie Chen, and KR Julian Chun

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Catheter ablation is a widely used, effective and safe treatment for AF. Pulsed field ablation (PFA), as a novel energy source for cardiac ablation, has been shown to be tissue selective and is expected to decrease damage to non-cardiac tissue while providing high efficacy in pulmonary vein isolation. The FARAPULSE ablation system (Boston Scientific) follows the idea of single-shot ablation and is the first device approved for clinical use in Europe. Since its approval, multiple high-volume centres have performed increasing numbers of PFA procedures in patients with AF and have published their experiences. This review summarises the current clinical experience regarding the use of PFA for AF using the FARAPULSE system. It provides an overview of its efficacy and safety.

Published
2023
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27. When Fulfillment Is Not Enough: Early Childhood Teacher Occupational Burnout and Turnover Intentions from a Job Demands and Resources Perspective

Author

Schaack, Diana D., Le, Vi-Nhuan, and Stedron, Jennifer

Abstract

Research Findings: This study examined the job demands and job resources of a sample of 273 early childhood teachers in Colorado. The study explored the relationships among their job demands and resources, occupational burnout, and turnover intentions using a two-level mediated model. Study findings suggest that teachers' emotional exhaustion and depersonalization from the work is a function of lack of job control, lack of collegial relationships within the program, and children's behaviors that they perceived to be challenging. However, teachers also reported being more fulfilled with their work when they worked in programs in which there was a shared vision and that allowed for greater job control. Additionally, teachers who earned lower wages, held a postsecondary degree, reported greater emotional exhaustion, and who expressed less of a shared vision with their organization were more likely to indicate intentions to leave their job. Higher levels of collegiality were indirectly related to lower turnover intentions via lower levels of emotional exhaustion among teachers. Policy or Practice: Study findings can be used to inform leadership development, teacher professional development, and workforce compensation policy to foster greater organizational health, to improve teacher well-being, and to promote teacher retention.

Published
2020
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28. Interleukin-3 protects against viral pneumonia in sepsis by enhancing plasmacytoid dendritic cell recruitment into the lungs and T cell priming

Author

Alan Bénard, Frederik J. Hansen, Florian Uhle, Bettina Klösch, Franziska Czubayko, Anke Mittelstädt, Anne Jacobsen, Paul David, Malgorzata J. Podolska, Anna Anthuber, Izabela Swierzy, Dominik Schaack, Petra Mühl-Zürbes, Alexander Steinkasserer, Michael Weyand, Markus A. Weigand, Thorsten Brenner, Christian Krautz, Robert Grützmann, and Georg F. Weber

Subjects
interleukin-3, sepsis, viral pneumonia, plasmacytoid dendritic cells, T cell priming, Immunologic diseases. Allergy, RC581-607
Abstract

RationaleSepsis, a global health burden, is often complicated by viral infections leading to increased long-term morbidity and mortality. Interleukin-3 (IL-3) has been identified as an important mediator amplifying acute inflammation in sepsis; however, its function in the host response to viral infections during sepsis remains elusive.ObjectivesTo investigate the role of IL-3 during viral pneumonia in sepsis.MethodsWe included septic patients from two different cohorts and used in vitro and in vivo assays. The obtained data were substantiated using a second model (SARS-CoV-2 infections).Measurements and main resultsLow plasma IL-3 levels were associated with increased herpes simplex virus (HSV) airway infections in septic patients, resulting in reduced overall survival. Likewise, Il-3-deficient septic mice were more susceptible to pulmonary HSV-1 infection and exhibited higher pulmonary inflammation than control mice. Mechanistically, IL-3 increases innate antiviral immunity by promoting the recruitment of circulating plasmacytoid dendritic cells (pDCs) into the airways and by enhancing pDC-mediated T cell activation upon viral stimulation. Interestingly, the ability of IL-3 to improve adaptive immunity was confirmed in patients with SARS-CoV-2 infections.ConclusionOur study identifies IL-3 as a predictive disease marker for viral reactivation in sepsis and reveals that IL-3 improves antiviral immunity by enhancing the recruitment and the function of pDCs.

Published
2023
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29. Gαq modulates the energy metabolism of osteoclasts

Author

Sushmita Chakraborty, Bianca Handrick, Dayoung Yu, Konrad A. Bode, Anna Hafner, Judith Schenz, Dominik Schaack, Florian Uhle, Taro Tachibana, Shigeki Kamitani, Thomas Vogl, and Katharina F. Kubatzky

Subjects
pasteurella mulfocida toxin, mitochondria, immunometabolism, OPA1, STAT3, Gαq, Microbiology, QR1-502
Abstract

IntroductionThe bacterial protein toxin Pasteurella multocida toxin (PMT) mediates RANKL-independent osteoclast differentiation. Although these osteoclasts are smaller, their resorptive activity is high which helps in efficient destruction of nasal turbinate bones of pigs.MethodsThe proteome of bone marrow-derived macrophages differentiated into osteoclasts with either RANKL or PMT was analysed. The results were verified by characterizing the metabolic activity using Seahorse analysis, a protein translation assay, immunoblots, real-time PCR as well as flow cytometry-based monitoring of mitochondrial activity and ROS production. A Gαq overexpression system using ER-Hoxb8 cells was used to identify Gαq-mediated metabolic effects on osteoclast differentiation and function.ResultsPMT induces the upregulation of metabolic pathways, which included strong glycolytic activity, increased expression of GLUT1 and upregulation of the mTOR pathway. As OxPhos components were expressed more efficiently, cells also displayed increased mitochondrial respiration. The heterotrimeric G protein Gαq plays a central role in this hypermetabolic cell activation as it triggers mitochondrial relocalisation of pSerSTAT3 and an increase in OPA1 expression. This seems to be caused by a direct interaction between STAT3 and OPA1 resulting in enhanced mitochondrial respiration. Overexpression of Gαq mimicked the hypermetabolic phenotype observed for PMT-induced osteoclasts and resulted in higher glycolytic and mitochondrial activity as well as increased bone resorptive activity. In addition, rheumatoid arthritis (RA) patients showed an increase in GNAQ expression, especially in the synovial fluid.DiscussionOur study suggests that Gαq plays a key role in PMT-induced osteoclastogenesis. Enhanced expression of GNAQ at the site of inflammation in RA patients indicates its pathophysiological relevance in the context of inflammatory bone disorders.

Published
2023
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30. Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in Mice

Author

Qiao, Liping, Wattez, Jean-Sebastien, Lee, Samuel, Nguyen, Amanda, Schaack, Jerome, Hay, William W, and Shao, Jianhua

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Pediatric, Diabetes, Perinatal Period - Conditions Originating in Perinatal Period, Nutrition, Metabolic and endocrine, Reproductive health and childbirth, Adaptation, Physiological, Adiponectin, Adipose Tissue, White, Animals, Blotting, Western, Body Weight, Diabetes, Gestational, Female, Fetus, Glucose, Glucose Clamp Technique, Glucose Intolerance, Hyperlipidemias, Immunohistochemistry, Insulin, Insulin Resistance, Insulin Secretion, Insulin-Secreting Cells, Lipolysis, Liver, Metabolism, Inborn Errors, Mice, Mice, Knockout, Organ Size, Pregnancy, Real-Time Polymerase Chain Reaction, Triglycerides, Medical and Health Sciences, Endocrinology & Metabolism, Biomedical and clinical sciences
Abstract

Hypoadiponectinemia has been widely observed in patients with gestational diabetes mellitus (GDM). To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (Adipoq-/- ) and wild-type (WT) mice were crossed to produce pregnant mouse models with or without adiponectin deficiency. Adenoviral vector-mediated in vivo transduction was used to reconstitute adiponectin during late pregnancy. Results showed that Adipoq-/- dams developed glucose intolerance and hyperlipidemia in late pregnancy. Increased fetal body weight was detected in Adipoq-/- dams. Adiponectin reconstitution abolished these metabolic defects in Adipoq-/- dams. Hepatic glucose and triglyceride production rates of Adipoq-/- dams were significantly higher than those of WT dams. Robustly enhanced lipolysis was found in gonadal fat of Adipoq-/- dams. Interestingly, similar levels of insulin-induced glucose disposal and insulin signaling in metabolically active tissues in Adipoq-/- and WT dams indicated that maternal adiponectin deficiency does not reduce insulin sensitivity. However, remarkably decreased serum insulin concentrations were observed in Adipoq-/- dams. Furthermore, β-cell mass, but not glucose-stimulated insulin release, in Adipoq-/- dams was significantly reduced compared with WT dams. Together, these results demonstrate that adiponectin plays an important role in controlling maternal metabolic adaptation to pregnancy.

Published
2017

31. Nanocellulose Composites as Smart Devices With Chassis, Light-Directed DNA Storage, Engineered Electronic Properties, and Chip Integration

Author

Elena Bencurova, Sergey Shityakov, Dominik Schaack, Martin Kaltdorf, Edita Sarukhanyan, Alexander Hilgarth, Christin Rath, Sergio Montenegro, Günter Roth, Daniel Lopez, and Thomas Dandekar

Subjects
nanocellulose, DNA storage, light-gated proteins, single-electron transistors, protein chip, Biotechnology, TP248.13-248.65
Abstract

The rapid development of green and sustainable materials opens up new possibilities in the field of applied research. Such materials include nanocellulose composites that can integrate many components into composites and provide a good chassis for smart devices. In our study, we evaluate four approaches for turning a nanocellulose composite into an information storage or processing device: 1) nanocellulose can be a suitable carrier material and protect information stored in DNA. 2) Nucleotide-processing enzymes (polymerase and exonuclease) can be controlled by light after fusing them with light-gating domains; nucleotide substrate specificity can be changed by mutation or pH change (read-in and read-out of the information). 3) Semiconductors and electronic capabilities can be achieved: we show that nanocellulose is rendered electronic by iodine treatment replacing silicon including microstructures. Nanocellulose semiconductor properties are measured, and the resulting potential including single-electron transistors (SET) and their properties are modeled. Electric current can also be transported by DNA through G-quadruplex DNA molecules; these as well as classical silicon semiconductors can easily be integrated into the nanocellulose composite. 4) To elaborate upon miniaturization and integration for a smart nanocellulose chip device, we demonstrate pH-sensitive dyes in nanocellulose, nanopore creation, and kinase micropatterning on bacterial membranes as well as digital PCR micro-wells. Future application potential includes nano-3D printing and fast molecular processors (e.g., SETs) integrated with DNA storage and conventional electronics. This would also lead to environment-friendly nanocellulose chips for information processing as well as smart nanocellulose composites for biomedical applications and nano-factories.

Published
2022
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32. MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries

Author

Justyna Ciolek, Claude Zoukimian, Justine Dhot, Mélanie Burban, Mathilde Triquigneaux, Benjamin Lauzier, Christelle Guimbert, Didier Boturyn, Marine Ferron, Lidia Ciccone, Livia Tepshi, Enrico Stura, Pierre Legrand, Philippe Robin, Gilles Mourier, Béatrice Schaack, Imen Fellah, Guillaume Blanchet, Chantal Gauthier-Erfanian, Rémy Beroud, Denis Servent, Michel De Waard, and Nicolas Gilles

Subjects
Snake venom, M2 muscarinic receptor, Bioactive peptide mass spectrometry, Peptide sequencing, Drug screening Peptide synthesis, Peptide folding, Arterial pressure, Therapeutics. Pharmacology, RM1-950
Abstract

All five muscarinic receptors have important physiological roles. The endothelial M2 and M3 subtypes regulate arterial tone through direct coupling to Gq or Gi/o proteins. Yet, we lack selective pharmacological drugs to assess the respective contribution of muscarinic receptors to a given function. We used mamba snake venoms to identify a selective M2R ligand to investigate its contribution to arterial contractions. Using a bio-guided screening binding assay, we isolated MT9 from the black mamba venom, a three-finger toxin active on the M2R subtype. After sequencing and chemical synthesis of MT9, we characterized its structure by X-ray diffraction and determined its pharmacological characteristics by binding assays, functional tests, and ex vivo experiments on rat and human arteries. Although MT9 belongs to the three-finger fold toxins family, it is phylogenetically apart from the previously discovered muscarinic toxins, suggesting that two groups of peptides evolved independently and in a convergent way to target muscarinic receptors. The affinity of MT9 for the M2R is 100 times stronger than that for the four other muscarinic receptors. It also antagonizes the M2R/Gi pathways in cell-based assays. MT9 acts as a non-competitive antagonist against acetylcholine or arecaine, with low nM potency, for the activation of isolated rat mesenteric arteries. These results were confirmed on human internal mammary arteries. In conclusion, MT9 is the first fully characterized M2R-specific natural toxin. It should provide a tool for further understanding of the effect of M2R in various arteries and may position itself as a new drug candidate in cardio-vascular diseases

Published
2022
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33. Yes They Can: Supporting Bachelor Degree Attainment for Early Childhood Practitioners

Author

Sakai, Laura, Kipnis, Fran, Whitebook, Marcy, and Schaack, Diana

Abstract

As part of a longitudinal study, the authors interviewed 73 nontraditional students regarding their perceptions of the challenges experienced and supports received as they returned to school to earn bachelor's degrees. All participants were working in the early care and education field. Interviewees perceived the cohort structure of their B.A. program as important to their academic success; this positive assessment increased over time and continued after graduation. A majority reported that program services such as financial assistance and the scheduling and location of classes were critically important throughout their participation in the degree programs. In contrast, academic and technological challenges reportedly decreased over time, and thus students' need for support such as tutoring, counseling services, and technology assistance decreased. Many students whose primary language was not English reported relying on English-language assistance throughout their school experience even when they perceived English academic work to be increasingly less challenging. These findings suggest that those who design and implement programs to assist degree attainment should invest in academic supports at the beginning of the program while other supports, including financial assistance, the schedule and location of classes, and the cohort itself, are critical throughout students' educational experience.

Published
2014

34. Quantum numbers of the $X(3872)$ state and orbital angular momentum in its $\rho^0 J\psi$ decay

Author

LHCb collaboration, Aaij, R., Beteta, C. Abellan, Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves Jr, A. A., Amato, S., Amerio, S., Amhis, Y., Anderlini, L., Anderson, J., Andreassen, R., Appleby, R. B., Gutierrez, O. Aquines, Archilli, F., Artamonov, A., Artuso, M., Aslanides, E., Auriemma, G., Bachmann, S., Back, J. J., Baesso, C., Balagura, V., Baldini, W., Barlow, R. J., Barschel, C., Barsuk, S., Barter, W., Bauer, Th., Bay, A., Beddow, J., Bedeschi, F., Bediaga, I., Belogurov, S., Belous, K., Belyaev, I., Ben-Haim, E., Benayoun, M., Bencivenni, G., Benson, S., Benton, J., Berezhnoy, A., Bernet, R., Bettler, M. -O., van Beuzekom, M., Bien, A., Bifani, S., Bird, T., Bizzeti, A., Bjørnstad, P. M., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bowcock, T. J. V., Bowen, E., Bozzi, C., Brambach, T., Brand, J. van den, Bressieux, J., Brett, D., Britsch, M., Britton, T., Brook, N. H., Brown, H., Burducea, I., Bursche, A., Busetto, G., Buytaert, J., Cadeddu, S., Callot, O., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carranza-Mejia, H., Carson, L., Akiba, K. Carvalho, Casse, G., Cattaneo, M., Cauet, Ch., Charles, M., Charpentier, Ph., Chen, P., Chiapolini, N., Chrzaszcz, M., Ciba, K., Vidal, X. Cid, Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Coca, C., Coco, V., Cogan, J., Cogneras, E., Collins, P., Comerma-Montells, A., Contu, A., Cook, A., Coombes, M., Coquereau, S., Corti, G., Couturier, B., Cowan, G. A., Craik, D., Cunliffe, S., Currie, R., D'Ambrosio, C., David, P., David, P. N. Y., De Bonis, I., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., Campos, M. De Oyanguren, De Paula, L., De Silva, W., De Simone, P., Decamp, D., Deckenhoff, M., Del Buono, L., Derkach, D., Deschamps, O., Dettori, F., Di Canto, A., Dijkstra, H., Dogaru, M., Donleavy, S., Dordei, F., Suárez, A. Dosil, Dossett, D., Dovbnya, A., Dupertuis, F., Dzhelyadin, R., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisenhardt, S., Eitschberger, U., Ekelhof, R., Eklund, L., Rifai, I. El, Elsasser, Ch., Elsby, D., Falabella, A., Färber, C., Fardell, G., Farinelli, C., Farry, S., Fave, V., Ferguson, D., Albor, V. Fernandez, Rodrigues, F. Ferreira, Ferro-Luzzi, M., Filippov, S., Fitzpatrick, C., Fontana, M., Fontanelli, F., Forty, R., Francisco, O., Frank, M., Frei, C., Frosini, M., Furcas, S., Furfaro, E., Torreira, A. Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garofoli, J., Garosi, P., Tico, J. Garra, Garrido, L., Gaspar, C., Gauld, R., Gersabeck, E., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Gligorov, V. V., Göbel, C., Golubkov, D., Golutvin, A., Gomes, A., Gordon, H., Gándara, M. Grabalosa, Diaz, R. Graciani, Cardoso, L. A. Granado, Graugés, E., Graziani, G., Grecu, A., Greening, E., Gregson, S., Grünberg, O., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haines, S. C., Hall, S., Hampson, T., Hansmann-Menzemer, S., Harnew, N., Harnew, S. T., Harrison, J., Hartmann, T., He, J., Heijne, V., Hennessy, K., Henrard, P., Morata, J. A. Hernando, van Herwijnen, E., Hicks, E., Hill, D., Hoballah, M., Hombach, C., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Hussain, N., Hutchcroft, D., Hynds, D., Iakovenko, V., Idzik, M., Ilten, P., Jacobsson, R., Jaeger, A., Jans, E., Jaton, P., Jing, F., John, M., Johnson, D., Jones, C. R., Jost, B., Kaballo, M., Kandybei, S., Karacson, M., Karbach, T. M., Kenyon, I. R., Kerzel, U., Ketel, T., Keune, A., Khanji, B., Kochebina, O., Komarov, I., Koopman, R. F., Koppenburg, P., Korolev, M., Kozlinskiy, A., Kravchuk, L., Kreplin, K., Kreps, M., Krocker, G., Krokovny, P., Kruse, F., Kucharczyk, M., Kudryavtsev, V., Kvaratskheliya, T., La Thi, V. N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, D., Lambert, R. W., Lanciotti, E., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Gac, R. Le, van Leerdam, J., Lees, J. -P., Lefèvre, R., Leflat, A., Lefrançois, J., Leo, S., Leroy, O., Leverington, B., Li, Y., Gioi, L. Li, Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., von Loeben, J., Lohn, S., Lopes, J. H., Asamar, E. Lopez, Lopez-March, N., Lu, H., Lucchesi, D., Luisier, J., Luo, H., Machefert, F., Machikhiliyan, I. V., Maciuc, F., Maev, O., Malde, S., Manca, G., Mancinelli, G., Marconi, U., Märki, R., Marks, J., Martellotti, G., Martens, A., Martin, L., Sánchez, A. Martín, Martinelli, M., Santos, D. Martinez, Tostes, D. Martins, Massafferri, A., Matev, R., Mathe, Z., Matteuzzi, C., Maurice, E., Mazurov, A., McCarthy, J., McNulty, R., Mcnab, A., Meadows, B., Meier, F., Meissner, M., Merk, M., Milanes, D. A., Minard, M. -N., Rodriguez, J. Molina, Monteil, S., Moran, D., Morawski, P., Morello, M. J., Mountain, R., Mous, I., Muheim, F., Müller, K., Muresan, R., Muryn, B., Muster, B., Naik, P., Nakada, T., Nandakumar, R., Nasteva, I., Needham, M., Neufeld, N., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nicol, M., Niess, V., Niet, R., Nikitin, N., Nikodem, T., Nomerotski, A., Novoselov, A., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Ogilvy, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Goicochea, J. M. Otalora, Owen, P., Pal, B. K., Palano, A., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C. J., Passaleva, G., Patel, G. D., Patel, M., Patrick, G. N., Patrignani, C., Pavel-Nicorescu, C., Alvarez, A. Pazos, Pellegrino, A., Penso, G., Altarelli, M. Pepe, Perazzini, S., Perego, D. L., Trigo, E. Perez, Yzquierdo, A. Pérez-Calero, Perret, P., Perrin-Terrin, M., Pessina, G., Petridis, K., Petrolini, A., Phan, A., Olloqui, E. Picatoste, Pietrzyk, B., Pilař, T., Pinci, D., Playfer, S., Casasus, M. Plo, Polci, F., Polok, G., Poluektov, A., Polycarpo, E., Popov, D., Popovici, B., Potterat, C., Powell, A., Prisciandaro, J., Pugatch, V., Navarro, A. Puig, Punzi, G., Qian, W., Rademacker, J. H., Rakotomiaramanana, B., Rangel, M. S., Raniuk, I., Rauschmayr, N., Raven, G., Redford, S., Reid, M. M., Reis, A. C. dos, Ricciardi, S., Richards, A., Rinnert, K., Molina, V. Rives, Romero, D. A. Roa, Robbe, P., Rodrigues, E., Perez, P. Rodriguez, Roiser, S., Romanovsky, V., Vidal, A. Romero, Rouvinet, J., Ruf, T., Ruffini, F., Ruiz, H., Valls, P. Ruiz, Sabatino, G., Silva, J. J. Saborido, Sagidova, N., Sail, P., Saitta, B., Salzmann, C., Sedes, B. Sanmartin, Sannino, M., Santacesaria, R., Rios, C. Santamarina, Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schindler, H., Schlupp, M., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M. -H., Schwemmer, R., Sciascia, B., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Sepp, I., Serra, N., Serrano, J., Seyfert, P., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Coutinho, R. Silva, Skwarnicki, T., Smith, N. A., Smith, E., Smith, M., Sokoloff, M. D., Soler, F. J. P., Soomro, F., Souza, D., De Paula, B. Souza, Spaan, B., Sparkes, A., Spradlin, P., Stagni, F., Stahl, S., Steinkamp, O., Stoica, S., Stone, S., Storaci, B., Straticiuc, M., Straumann, U., Subbiah, V. K., Swientek, S., Syropoulos, V., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Teklishyn, M., Teodorescu, E., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Tolk, S., Tonelli, D., Topp-Joergensen, S., Torr, N., Tournefier, E., Tourneur, S., Tran, M. T., Tresch, M., Tsaregorodtsev, A., Tsopelas, P., Tuning, N., Garcia, M. Ubeda, Ukleja, A., Urner, D., Uwer, U., Vagnoni, V., Valenti, G., Gomez, R. Vazquez, Regueiro, P. Vazquez, Vecchi, S., Velthuis, J. J., Veltri, M., Veneziano, G., Vesterinen, M., Viaud, B., Vieira, D., Vilasis-Cardona, X., Vollhardt, A., Volyanskyy, D., Voong, D., Vorobyev, A., Vorobyev, V., Voß, C., Voss, H., Waldi, R., Wallace, R., Wandernoth, S., Wang, J., Ward, D. R., Watson, N. K., Webber, A. D., Websdale, D., Whitehead, M., Wicht, J., Wiechczynski, J., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M. P., Williams, M., Wilson, F. F., Wishahi, J., Witek, M., Wotton, S. A., Wright, S., Wu, S., Wyllie, K., Xie, Y., Xing, F., Xing, Z., Yang, Z., Young, R., Yuan, X., Yushchenko, O., Zangoli, M., Zavertyaev, M., Zhang, F., Zhang, L., Zhang, W. C., Zhang, Y., Zhelezov, A., Zhokhov, A., Zhong, L., and Zvyagin, A.

Subjects
High Energy Physics - Experiment
Abstract

Angular correlations in $B^+\to X(3872) K^+$ decays, with $X(3872)\to \rho^0 J/\psi$, $\rho^0\to\pi^+\pi^-$ and $J/\psi \to\mu^+\mu^-$, are used to measure orbital angular momentum contributions and to determine the $J^{PC}$ value of the $X(3872)$ meson. The data correspond to an integrated luminosity of 3.0 fb$^{-1}$ of proton-proton collisions collected with the LHCb detector. This determination, for the first time performed without assuming a value for the orbital angular momentum, confirms the quantum numbers to be $J^{PC}=1^{++}$. The $X(3872)$ is found to decay predominantly through S wave and an upper limit of $4\%$ at $95\%$ C.L. is set on the fraction of D wave., Comment: 16 pages, 4 figures

Published
2015
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35. Advanced Content Coverage at Kindergarten: Are There Trade-Offs between Academic Achievement and Social-Emotional Skills?

Author

Le, Vi-Nhuan, Schaack, Diana, Neishi, Kristen, Hernandez, Marc W., and Blank, Rolf

Abstract

Policymakers have advocated academic skills building at kindergarten as a way of improving student achievement. However, early childhood educators have concerns with this policy as gains in achievement may come at the expense of children's social-emotional skills. Using a nationally representative data set of kindergartners, we find that advanced academic content, defined as academic skills typically taught at a higher grade, was associated not only with improved math and English/language arts achievement but also with improved social-emotional outcomes. Greater exposure to advanced content was associated with better interpersonal skills, better approaches to learning, better attentional focus, and lower externalizing behaviors. The results suggest that advanced academic content can be taught without compromising children's social-emotional skills.

Published
2019
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36. Long‐term follow‐up of patients treated with laser balloon for atrial fibrillation: A high volume center experience with the first‐ and second‐generation laser balloon.

Author

Urbanek, Lukas, Bordignon, Stefano, Tohoku, Shota, Hirokami, Jun, Nagase, Takahiko, Chen, Shaojie, Schaack, David, Chun, K. R. Julian, and Schmidt, Boris

Subjects
TRANSLUMINAL angioplasty, POSTOPERATIVE care, PEARSON correlation (Statistics), STATISTICAL hypothesis testing, PATIENT safety, LONG-term health care, TREATMENT effectiveness, RETROSPECTIVE studies, DESCRIPTIVE statistics, PREOPERATIVE care, CHI-squared test, MULTIVARIATE analysis, SURGICAL complications, KAPLAN-Meier estimator, LOG-rank test, ATRIAL fibrillation, MEDICAL records, ACQUISITION of data, STATISTICS, LASER angioplasty, HEALTH facilities, COMPARATIVE studies, CATHETER ablation, DATA analysis software, PATIENT aftercare, FLUOROSCOPY, PROPORTIONAL hazards models
Abstract

Background: Laser balloon (LB) pulmonary vein isolation (PVI) is an established ablation technique for atrial fibrillation (AF). We report long‐term follow‐up and procedural data of LB‐PVI and we compare the first and second LB generation. Methods: Patients undergoing LB ablation with first‐ (LB1) or second‐generation LB (LB2) for AF were retrospectively enrolled and divided into two groups. Procedural endpoint was complete PVI. Clinical success was defined as no recurrence of AF/atrial tachycardia after a 90 days blanking period. Results: 538 patients were included (age 66 ± 10 years, 58% paroxysmal AF), 427 in LB1 and 111 in LB2. 2079 PVs were targeted and 2073 (99.7%) were successfully isolated; 2027 (97.5%) using solely the LB. Additional touch‐up ablation was limited (46 PVs; 2.2%) with no difference between the groups. Procedural (LB1: 120 ± 33 minutes vs. LB2: 99 ± 22 min; p <.001) and fluoroscopy time (LB1: 11.2 ± 5 min vs. LB2: 8.5 ± 3 min; p <.001) were shorter with LB2. The complication rate was 8.9% (LB1: 10.1% vs. LB2: 4.5%; p =.067) with most complications resulting from the access site (21/48). Overall freedom from AF after 1‐year was 73.7% (paroxysmal AF: 76.9%; persistent AF: 69.3%; p <.001) with no difference between the groups (LB1: 73.4% vs. LB2: 74.7%; p =.491). Conclusion: LB showed a high efficacy and acceptable safety, with numerically lower complication rates with the second‐generation LB. Procedure and fluoroscopy times were shorter with LB2. Overall, 73.7% of patients were free from AF at 1‐year, with comparable results among both generations. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1.

Author

Qiao, Liping, Wattez, Jean-Sebastien, Lee, Samuel, Guo, Zhuyu, Schaack, Jerome, Hay, William W, Zita, Matteo Moretto, Parast, Mana, and Shao, Jianhua

Subjects
Cells, Cultured, Trophoblasts, Placenta, Animals, Mice, Knockout, Humans, Mice, Indoles, Blood Glucose, Fatty Acids, Nonesterified, Triglycerides, Insulin-Like Growth Factor Binding Protein 1, PPAR alpha, Pregnancy, Female, Adiponectin, Fetus, Growth, IGF-binding protein, Nutrition, Pediatric, Perinatal Period - Conditions Originating in Perinatal Period, Underpinning research, 1.1 Normal biological development and functioning, Reproductive health and childbirth, Clinical Sciences, Paediatrics and Reproductive Medicine, Public Health and Health Services, Endocrinology & Metabolism
Abstract

Aims/hypothesisThe main objective of this study was to investigate whether maternal adiponectin regulates fetal growth through the endocrine system in the fetal compartment.MethodsAdiponectin knockout (Adipoq (-/-) ) mice and in vivo adenovirus-mediated reconstitution were used to study the regulatory effect of maternal adiponectin on fetal growth. Primary human trophoblast cells were treated with adiponectin and a specific peroxisome proliferator-activated receptor α (PPARα) agonist or antagonist to study the underlying mechanism through which adiponectin regulates fetal growth.ResultsThe body weight of fetuses from Adipoq (-/-) dams was significantly greater than that of wild-type dams at both embryonic day (E)14.5 and E18.5. Adenoviral vector-mediated maternal adiponectin reconstitution attenuated the increased fetal body weight induced by maternal adiponectin deficiency. Significantly increased blood glucose, triacylglycerol and NEFA levels were observed in Adipoq (-/-) dams, suggesting that nutrient supply contributes to maternal adiponectin-regulated fetal growth. Although fetal blood IGF-1 concentrations were comparable in fetuses from Adipoq (-/-) and wild-type dams, remarkably low levels of IGF-binding protein 1 (IGFBP-1) were observed in the serum of fetuses from Adipoq (-/-) dams. IGFBP-1 was identified in the trophoblast cells of human and mouse placentas. Maternal fasting robustly increased IGFBP-1 levels in mouse placentas, while reducing fetal weight. Significantly low IGFBP-1 levels were found in placentas of Adipoq (-/-) dams. Adiponectin treatment increased IGFBP-1 levels in primary cultured human trophoblast cells, while the PPARα antagonist, MK886, abolished this stimulatory effect.Conclusions/interpretationThese results indicate that, in addition to nutrient supply, maternal adiponectin inhibits fetal growth by increasing IGFBP-1 expression in trophoblast cells.

Published
2016

38. Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta

Author

Kanost, Michael R, Arrese, Estela L, Cao, Xiaolong, Chen, Yun-Ru, Chellapilla, Sanjay, Goldsmith, Marian R, Grosse-Wilde, Ewald, Heckel, David G, Herndon, Nicolae, Jiang, Haobo, Papanicolaou, Alexie, Qu, Jiaxin, Soulages, Jose L, Vogel, Heiko, Walters, James, Waterhouse, Robert M, Ahn, Seung-Joon, Almeida, Francisca C, An, Chunju, Aqrawi, Peshtewani, Bretschneider, Anne, Bryant, William B, Bucks, Sascha, Chao, Hsu, Chevignon, Germain, Christen, Jayne M, Clarke, David F, Dittmer, Neal T, Ferguson, Laura CF, Garavelou, Spyridoula, Gordon, Karl HJ, Gunaratna, Ramesh T, Han, Yi, Hauser, Frank, He, Yan, Heidel-Fischer, Hanna, Hirsh, Ariana, Hu, Yingxia, Jiang, Hongbo, Kalra, Divya, Klinner, Christian, König, Christopher, Kovar, Christie, Kroll, Ashley R, Kuwar, Suyog S, Lee, Sandy L, Lehman, Rüdiger, Li, Kai, Li, Zhaofei, Liang, Hanquan, Lovelace, Shanna, Lu, Zhiqiang, Mansfield, Jennifer H, McCulloch, Kyle J, Mathew, Tittu, Morton, Brian, Muzny, Donna M, Neunemann, David, Ongeri, Fiona, Pauchet, Yannick, Pu, Ling-Ling, Pyrousis, Ioannis, Rao, Xiang-Jun, Redding, Amanda, Roesel, Charles, Sanchez-Gracia, Alejandro, Schaack, Sarah, Shukla, Aditi, Tetreau, Guillaume, Wang, Yang, Xiong, Guang-Hua, Traut, Walther, Walsh, Tom K, Worley, Kim C, Wu, Di, Wu, Wenbi, Wu, Yuan-Qing, Zhang, Xiufeng, Zou, Zhen, Zucker, Hannah, Briscoe, Adriana D, Burmester, Thorsten, Clem, Rollie J, Feyereisen, René, Grimmelikhuijzen, Cornelis JP, Hamodrakas, Stavros J, Hansson, Bill S, Huguet, Elisabeth, Jermiin, Lars S, Lan, Que, Lehman, Herman K, Lorenzen, Marce, Merzendorfer, Hans, Michalopoulos, Ioannis, Morton, David B, Muthukrishnan, Subbaratnam, Oakeshott, John G, Palmer, Will, Park, Yoonseong, and Passarelli, A Lorena

Subjects
Biological Sciences, Bioinformatics and Computational Biology, Genetics, Tobacco, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Animals, Gene Expression, Gene Expression Profiling, Genome, Insect, Larva, Manduca, Pupa, Sequence Analysis, DNA, Synteny, Lepidoptera, Insect, Tobacco hornworm, Moth, Insect biochemistry, Innate immunity, Medicinal and Biomolecular Chemistry, Biochemistry and Cell Biology, Zoology, Entomology, Biochemistry and cell biology
Abstract

Manduca sexta, known as the tobacco hornworm or Carolina sphinx moth, is a lepidopteran insect that is used extensively as a model system for research in insect biochemistry, physiology, neurobiology, development, and immunity. One important benefit of this species as an experimental model is its extremely large size, reaching more than 10 g in the larval stage. M. sexta larvae feed on solanaceous plants and thus must tolerate a substantial challenge from plant allelochemicals, including nicotine. We report the sequence and annotation of the M. sexta genome, and a survey of gene expression in various tissues and developmental stages. The Msex_1.0 genome assembly resulted in a total genome size of 419.4 Mbp. Repetitive sequences accounted for 25.8% of the assembled genome. The official gene set is comprised of 15,451 protein-coding genes, of which 2498 were manually curated. Extensive RNA-seq data from many tissues and developmental stages were used to improve gene models and for insights into gene expression patterns. Genome wide synteny analysis indicated a high level of macrosynteny in the Lepidoptera. Annotation and analyses were carried out for gene families involved in a wide spectrum of biological processes, including apoptosis, vacuole sorting, growth and development, structures of exoskeleton, egg shells, and muscle, vision, chemosensation, ion channels, signal transduction, neuropeptide signaling, neurotransmitter synthesis and transport, nicotine tolerance, lipid metabolism, and immunity. This genome sequence, annotation, and analysis provide an important new resource from a well-studied model insect species and will facilitate further biochemical and mechanistic experimental studies of many biological systems in insects.

Published
2016

39. The Project Baseline Health Study: a step towards a broader mission to map human health

Author

Kristine Arges, Themistocles Assimes, Vikram Bajaj, Suresh Balu, Mustafa R. Bashir, Laura Beskow, Rosalia Blanco, Robert Califf, Paul Campbell, Larry Carin, Victoria Christian, Scott Cousins, Millie Das, Marie Dockery, Pamela S. Douglas, Ashley Dunham, Julie Eckstrand, Dominik Fleischmann, Emily Ford, Elizabeth Fraulo, John French, Sanjiv S. Gambhir, Geoffrey S. Ginsburg, Robert C. Green, Francois Haddad, Adrian Hernandez, John Hernandez, Erich S. Huang, Glenn Jaffe, Daniel King, Lynne H. Koweek, Curtis Langlotz, Yaping J. Liao, Kenneth W. Mahaffey, Kelly Marcom, William J. Marks, David Maron, Reid McCabe, Shannon McCall, Rebecca McCue, Jessica Mega, David Miller, Lawrence H. Muhlbaier, Rajan Munshi, L. Kristin Newby, Ezra Pak-Harvey, Bray Patrick-Lake, Michael Pencina, Eric D. Peterson, Fatima Rodriguez, Scarlet Shore, Svati Shah, Steven Shipes, George Sledge, Susie Spielman, Ryan Spitler, Terry Schaack, Geeta Swamy, Martin J. Willemink, and Charlene A. Wong

Subjects
Computer applications to medicine. Medical informatics, R858-859.7
Abstract

Abstract The Project Baseline Health Study (PBHS) was launched to map human health through a comprehensive understanding of both the health of an individual and how it relates to the broader population. The study will contribute to the creation of a biomedical information system that accounts for the highly complex interplay of biological, behavioral, environmental, and social systems. The PBHS is a prospective, multicenter, longitudinal cohort study that aims to enroll thousands of participants with diverse backgrounds who are representative of the entire health spectrum. Enrolled participants will be evaluated serially using clinical, molecular, imaging, sensor, self-reported, behavioral, psychological, environmental, and other health-related measurements. An initial deeply phenotyped cohort will inform the development of a large, expanded virtual cohort. The PBHS will contribute to precision health and medicine by integrating state of the art testing, longitudinal monitoring and participant engagement, and by contributing to the development of an improved platform for data sharing and analysis.

Published
2020
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40. Erratum to: Measurement of $$\psi (2S)$$ ψ(2S) meson production in pp collisions at $$\sqrt{s}=7\,\hbox {TeV}$$ s=7TeV

Author

R. Aaij, C. Abellán Beteta, B. Adeva, M. Adinolfi, C. Adrover, A. Affolder, Z. Ajaltouni, J. Albrecht, F. Alessio, M. Alexander, G. Alkhazov, P. Alvarez Cartelle, A. A. Alves Jr, S. Amato, Y. Amhis, J. Anderson, F. Andrianala, R. B. Appleby, F. Archilli, L. Arrabito, A. Artamonov, M. Artuso, E. Aslanides, G. Auriemma, S. Bachmann, J. J. Back, D. S. Bailey, V. Balagura, W. Baldini, R. J. Barlow, C. Barschel, S. Barsuk, W. Barter, A. Bates, Th. Bauer, A. Bay, I. Bediaga, S. Belogurov, K. Belous, I. Belyaev, E. Ben-Haim, M. Benayoun, G. Bencivenni, S. Benson, J. Benton, R. Bernet, M. O. Bettler, M. van Beuzekom, A. Bien, S. Bifani, A. Bizzeti, P. M. Bjørnstad, T. Blake, F. Blanc, C. Blanks, J. Blouw, S. Blusk, A. Bobrov, V. Bocci, A. Bondar, N. Bondar, W. Bonivento, S. Borghi, A. Borgia, T. J. V. Bowcock, C. Bozzi, T. Brambach, J. van den Brand, J. Bressieux, D. Brett, M. Britsch, T. Britton, N. H. Brook, H. Brown, A. Bursche, J. Buytaert, A. Büchler-Germann, S. Cadeddu, O. Callot, M. Calvi, M. Calvo Gomez, A. Camboni, P. Campana, A. Carbone, G. Carboni, R. Cardinale, A. Cardini, L. Carson, K. Carvalho Akiba, G. Casse, M. Cattaneo, Ch. Cauet, M. Charles, Ph. Charpentier, N. Chiapolini, M. Chrzaszcz, P. Ciambrone, K. Ciba, X. Cid Vidal, G. Ciezarek, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Coca, V. Coco, J. Cogan, P. Collins, A. Comerma-Montells, F. Constantin, A. Cook, M. Coombes, G. Corti, B. Couturier, G. A. Cowan, R. Currie, C. D’Ambrosio, P. David, P. N. Y. David, O. De Aguiar Francisco, K. De Bruyn, M. De Cian, F. De Lorenzi, J. M. De Miranda, L. De Paula, P. De Simone, D. Decamp, M. Deckenhoff, H. Degaudenzi, L. Del Buono, C. Deplano, D. Derkach, O. Deschamps, F. Dettori, J. Dickens, H. Dijkstra, P. Diniz Batista, F. Domingo Bonal, S. Donleavy, F. Dordei, A. Dosil Suárez, D. Dossett, A. Dovbnya, F. Dupertuis, R. Dzhelyadin, A. Dziurda, S. Easo, U. Egede, V. Egorychev, S. Eidelman, D. van Eijk, F. Eisele, S. Eisenhardt, R. Ekelhof, L. Eklund, Ch. Elsasser, D. Elsby, D. Esperante Pereira, A. Falabella, E. Fanchini, G. Fardell, C. Farinelli, S. Farry, V. Fave, V. Fernandez Albor, F. Ferreira Rodrigues, M. Ferro-Luzzi, S. Filippov, C. Fitzpatrick, M. Fontana, F. Fontanelli, R. Forty, M. Frank, C. Frei, M. Frosini, S. Furcas, C. Färber, A. Gallas Torreira, D. Galli, M. Gandelman, P. Gandini, Y. Gao, J-C. Garnier, J. Garofoli, J. Garra Tico, L. Garrido, D. Gascon, C. Gaspar, R. Gauld, N. Gauvin, M. Gersabeck, T. Gershon, Ph. Ghez, V. Gibson, V. V. Gligorov, D. Golubkov, A. Golutvin, A. Gomes, H. Gordon, C. Gotti, M. Grabalosa Gándara, R. Graciani Diaz, L. A. Granado Cardoso, E. Graugés, G. Graziani, A. Grecu, E. Greening, S. Gregson, B. Gui, E. Gushchin, Yu. Guz, T. Gys, C. Göbel, C. Hadjivasiliou, G. Haefeli, C. Haen, S. C. Haines, T. Hampson, S. Hansmann-Menzemer, R. Harji, N. Harnew, J. Harrison, P. F. Harrison, T. Hartmann, J. He, V. Heijne, K. Hennessy, P. Henrard, J. A. Hernando Morata, E. van Herwijnen, E. Hicks, K. Holubyev, W. Hulsbergen, P. Hunt, T. Huse, R. S. Huston, D. Hutchcroft, D. Hynds, V. Iakovenko, P. Ilten, J. Imong, A. Inyakin, R. Jacobsson, A. Jaeger, M. Jahjah Hussein, E. Jans, F. Jansen, P. Jaton, B. Jean-Marie, F. Jing, M. John, D. Johnson, C. R. Jones, B. Jost, S. Kandybei, M. Karacson, T. M. Karbach, J. Keaveney, I. R. Kenyon, U. Kerzel, T. Ketel, A. Keune, B. Khanji, Y. M. Kim, M. Knecht, R. F. Koopman, P. Koppenburg, A. Kozlinskiy, L. Kravchuk, K. Kreplin, M. Kreps, G. Krocker, P. Krokovny, F. Kruse, K. Kruzelecki, M. Kucharczyk, T. Kvaratskheliya, V. N. La Thi, D. Lacarrere, G. Lafferty, A. Lai, D. Lambert, R. W. Lambert, E. Lanciotti, G. Lanfranchi, C. Langenbruch, T. Latham, C. Lazzeroni, R. Le Gac, J. van Leerdam, J.-P. Lees, A. Leflat, J. Lefrançois, R. Lefèvre, O. Leroy, T. Lesiak, L. Li, P.-R. Li, L. Li Gioi, M. Lieng, M. Liles, R. Lindner, C. Linn, B. Liu, G. Liu, J. von Loeben, J. H. Lopes, E. Lopez Asamar, N. Lopez-March, H. Lu, J. Luisier, X.-R. Lyu, A. Mac Raighne, F. Machefert, F. Maciuc, O. Maev, S. Malde, R. M. D. Mamunur, G. Manca, G. Mancinelli, N. Mangiafave, J. F. Marchand, U. Marconi, J. Marks, G. Martellotti, A. Martens, L. Martin, D. Martinez Santos, A. Martín Sánchez, A. Massafferri, Z. Mathe, C. Matteuzzi, M. Matveev, E. Maurice, B. Maynard, A. Mazurov, G. McGregor, R. McNulty, M. Meissner, M. Merk, J. Merkel, R. Messi, S. Miglioranzi, D. A. Milanes, M.-N. Minard, J. Molina Rodriguez, S. Monteil, D. Moran, P. Morawski, R. Mountain, I. Mous, F. Muheim, R. Muresan, B. Muster, M. Musy, J. Mylroie-Smith, R. Märki, K. Müller, P. Naik, T. Nakada, R. Nandakumar, I. Nasteva, M. Nedos, M. Needham, N. Neufeld, A. D. Nguyen, C. Nguyen-Mau, M. Nicol, V. Niess, N. Nikitin, T. Nikodem, A. Nomerotski, A. Novoselov, A. Oblakowska-Mucha, V. Obraztsov, S. Oggero, S. Ogilvy, R. Oldeman, J. M. Otalora Goicochea, P. Owen, B. K. Pal, J. Palacios, A. Palano, M. Palutan, J. Panman, A. Papanestis, M. Pappagallo, C. Parkes, C. J. Parkinson, G. Passaleva, G. D. Patel, M. Patel, S. K. Paterson, G. N. Patrick, C. Patrignani, A. Pellegrino, G. Penso, M. Pepe Altarelli, S. Perazzini, D. L. Perego, P. Perret, M. Perrin-Terrin, A. Petrella, A. Petrolini, A. Phan, E. Picatoste Olloqui, B. Pie Valls, B. Pietrzyk, T. Pilař, D. Pinci, R. Plackett, S. Playfer, M. Plo Casasus, G. Polok, A. Poluektov, I. Polyakov, E. Polycarpo, D. Popov, B. Popovici, C. Potterat, A. Powell, J. Prisciandaro, V. Pugatch, A. Puig Navarro, A. Pérez-Calero Yzquierdo, W. Qian, J. H. Rademacker, B. Rakotomiaramanana, M. S. Rangel, I. Raniuk, G. Raven, S. Redford, M. M. Reid, A. C. dos Reis, S. Ricciardi, A. Richards, K. Rinnert, D. A. Roa Romero, P. Robbe, E. Rodrigues, P. Rodriguez Perez, G. J. Rogers, S. Roiser, V. Romanovskiy, J. Rouvinet, T. Ruf, H. Ruiz, G. Sabatino, J. J. Saborido Silva, N. Sagidova, P. Sail, B. Saitta, C. Salzmann, M. Sannino, R. Santacesaria, C. Santamarina Rios, R. Santinelli, E. Santovetti, M. Sapunov, A. Sarti, C. Satriano, A. Satta, M. Saur, D. Savrina, P. Schaack, M. Schiller, S. Schleich, M. Schlupp, M. Schmelling, B. Schmidt, O. Schneider, A. Schopper, M. H. Schune, R. Schwemmer, B. Sciascia, A. Sciubba, A. Semennikov, K. Senderowska, I. Sepp, N. Serra, J. Serrano, P. Seyfert, M. Shapkin, Y. Shcheglov, T. Shears, L. Shekhtman, V. Shevchenko, A. Shires, R. Silva Coutinho, T. Skwarnicki, E. Smith, K. Sobczak, F. J. P. Soler, A. Solomin, F. Soomro, B. Souza De Paula, B. Spaan, A. Sparkes, P. Spradlin, F. Stagni, S. Stahl, O. Steinkamp, O. Stenyakin, S. Stoica, S. Stone, B. Storaci, M. Straticiuc, U. Straumann, V. K. Subbiah, S. Swientek, M. Szczekowski, P. Szczypka, T. Szumlak, S. T’Jampens, E. Teodorescu, F. Teubert, E. Thomas, J. van Tilburg, V. Tisserand, M. Tobin, N. Torr, E. Tournefier, S. Tourneur, M. T. Tran, A. Tsaregorodtsev, N. Tuning, M. Ubeda Garcia, A. Ukleja, P. Urquijo, U. Uwer, V. Vagnoni, G. Valenti, R. Vazquez Gomez, P. Vazquez Regueiro, S. Vecchi, J. J. Velthuis, M. Veltri, B. Viaud, I. Videau, D. Vieira, X. Vilasis-Cardona, J. Visniakov, A. Vollhardt, D. Volyanskyy, D. Voong, A. Vorobyev, S. Wandernoth, J. Wang, D. R. Ward, N. K. Watson, A. D. Webber, D. Websdale, M. Whitehead, D. Wiedner, L. Wiggers, G. Wilkinson, M. P. Williams, M. Williams, F. F. Wilson, J. Wishahi, M. Witek, W. Witzeling, S. A. Wotton, K. Wyllie, Y. Xie, Z. Xing, Z. Yang, R. Young, O. Yushchenko, M. Zangoli, M. Zavertyaev, F. Zhang, L. Zhang, W. C. Zhang, Y. Zhang, A. Zhelezov, A. Zhokhov, L. Zhong, A. Zvyagin, and LHCb Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

This erratum corrects measurements of the prompt and secondary (from-b).

Published
2020
Full Text
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42. Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice.

Author

Qiao, Liping, Guo, Zhuyu, Bosco, Chris, Guidotti, Stefano, Wang, Yunfeng, Wang, Mingyong, Parast, Mana, Schaack, Jerome, Hay, William W, Moore, Thomas R, and Shao, Jianhua

Subjects
Cell Line, Trophoblasts, Placenta, Animals, Mice, Inbred C57BL, Humans, Mice, Pregnancy Complications, Overnutrition, Obesity, Disease Models, Animal, Lipoprotein Lipase, Glycerol-3-Phosphate O-Acyltransferase, Fatty Acids, Nonesterified, Triglycerides, CCAAT-Enhancer-Binding Protein-alpha, Receptors, LDL, PPAR gamma, RNA, Messenger, Maternal Exposure, Pregnancy, Female, Fatty Acid-Binding Proteins, 1-Acylglycerol-3-Phosphate O-Acyltransferase, Sirtuin 1, Diet, High-Fat, Fatty Acid Binding Protein 3, CD36 Antigens, Nutrition, 5.1 Pharmaceuticals, Cardiovascular, Medical and Health Sciences, Endocrinology & Metabolism
Abstract

This study investigated how maternal overnutrition and obesity regulate expression and activation of proteins that facilitate lipid transport in the placenta. To create a maternal overnutrition and obesity model, primiparous C57BL/6 mice were fed a high-fat (HF) diet throughout gestation. Fetuses from HF-fed dams had significantly increased serum levels of free fatty acid and body fat. Despite no significant difference in placental weight, lipoprotein lipase (LPL) protein levels and activity were remarkably elevated in placentas from HF-fed dams. Increased triglyceride content and mRNA levels of CD36, VLDLr, FABP3, FABPpm, and GPAT2 and -3 were also found in placentas from HF-fed dams. Although both peroxisome proliferator-activated receptor-γ (PPARγ) and CCAAT/enhancer binding protein-α protein levels were significantly increased in placentas of the HF group, only PPARγ exhibited a stimulative effect on LPL expression in cultured JEG-3 human trophoblasts. Maternal HF feeding remarkably decreased SIRT1 expression in placentas. Through use of an SIRT1 activator and inhibitor and cultured trophoblasts, an inhibitory effect of SIRT1 on LPL expression was demonstrated. We also found that SIRT1 suppresses PPARγ expression in trophoblasts. Most importantly, inhibition of PPARγ abolished the SIRT1-mediated regulatory effect on LPL expression. Together, these results indicate that maternal overnutrition induces LPL expression in trophoblasts by reducing the inhibitory effect of SIRT1 on PPARγ.

Published
2015

43. Observation of the decay $B_s^0\to\bar{D}^0\phi$

Author

The LHCb collaboration, Aaij, R., Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves Jr, A. A., Amato, S., Amerio, S., Amhis, Y., Anderlini, L., Anderson, J., Andreassen, R., Andrews, J. E., Appleby, R. B., Gutierrez, O. Aquines, Archilli, F., Artamonov, A., Artuso, M., Aslanides, E., Auriemma, G., Baalouch, M., Bachmann, S., Back, J. J., Baesso, C., Balagura, V., Baldini, W., Barlow, R. J., Barschel, C., Barsuk, S., Barter, W., Bauer, Th., Bay, A., Beddow, J., Bedeschi, F., Bediaga, I., Belogurov, S., Belous, K., Belyaev, I., Ben-Haim, E., Bencivenni, G., Benson, S., Benton, J., Berezhnoy, A., Bernet, R., Bettler, M. -O., van Beuzekom, M., Bien, A., Bifani, S., Bird, T., Bizzeti, A., Bjørnstad, P. M., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bowcock, T. J. V., Bowen, E., Bozzi, C., Brambach, T., Brand, J. van den, Bressieux, J., Brett, D., Britsch, M., Britton, T., Brook, N. H., Brown, H., Burducea, I., Bursche, A., Busetto, G., Buytaert, J., Cadeddu, S., Callot, O., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Perez, D. Campora, Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carranza-Mejia, H., Carson, L., Akiba, K. Carvalho, Casse, G., Garcia, L. Castillo, Cattaneo, M., Cauet, Ch., Cenci, R., Charles, M., Charpentier, Ph., Chen, P., Chiapolini, N., Chrzaszcz, M., Ciba, K., Vidal, X. Cid, Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Coca, C., Coco, V., Cogan, J., Cogneras, E., Collins, P., Comerma-Montells, A., Contu, A., Cook, A., Coombes, M., Coquereau, S., Corti, G., Couturier, B., Cowan, G. A., Craik, D. C., Cunliffe, S., Currie, R., D'Ambrosio, C., David, P., David, P. N. Y., Davis, A., De Bonis, I., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., De Paula, L., De Silva, W., De Simone, P., Decamp, D., Deckenhoff, M., Del Buono, L., Déléage, N., Derkach, D., Deschamps, O., Dettori, F., Di Canto, A., Dijkstra, H., Dogaru, M., Donleavy, S., Dordei, F., Suárez, A. Dosil, Dossett, D., Dovbnya, A., Dupertuis, F., Durante, P., Dzhelyadin, R., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisenhardt, S., Eitschberger, U., Ekelhof, R., Eklund, L., Rifai, I. El, Elsasser, Ch., Falabella, A., Färber, C., Fardell, G., Farinelli, C., Farry, S., Ferguson, D., Albor, V. Fernandez, Rodrigues, F. Ferreira, Ferro-Luzzi, M., Filippov, S., Fiore, M., Fitzpatrick, C., Fontana, M., Fontanelli, F., Forty, R., Francisco, O., Frank, M., Frei, C., Frosini, M., Furcas, S., Furfaro, E., Torreira, A. Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garofoli, J., Garosi, P., Tico, J. Garra, Garrido, L., Gaspar, C., Gauld, R., Gersabeck, E., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Giubega, L., Gligorov, V. V., Göbel, C., Golubkov, D., Golutvin, A., Gomes, A., Gorbounov, P., Gordon, H., Gotti, C., Gándara, M. Grabalosa, Diaz, R. Graciani, Cardoso, L. A. Granado, Graugés, E., Graziani, G., Grecu, A., Greening, E., Gregson, S., Griffith, P., Grünberg, O., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haines, S. C., Hall, S., Hamilton, B., Hampson, T., Hansmann-Menzemer, S., Harnew, N., Harnew, S. T., Harrison, J., Hartmann, T., He, J., Head, T., Heijne, V., Hennessy, K., Henrard, P., Morata, J. A. Hernando, van Herwijnen, E., Hess, M., Hicheur, A., Hicks, E., Hill, D., Hoballah, M., Hombach, C., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Hussain, N., Hutchcroft, D., Hynds, D., Iakovenko, V., Idzik, M., Ilten, P., Jacobsson, R., Jaeger, A., Jans, E., Jaton, P., Jawahery, A., Jing, F., John, M., Johnson, D., Jones, C. R., Joram, C., Jost, B., Kaballo, M., Kandybei, S., Kanso, W., Karacson, M., Karbach, T. M., Kenyon, I. R., Ketel, T., Keune, A., Khanji, B., Kochebina, O., Komarov, I., Koopman, R. F., Koppenburg, P., Korolev, M., Kozlinskiy, A., Kravchuk, L., Kreplin, K., Kreps, M., Krocker, G., Krokovny, P., Kruse, F., Kucharczyk, M., Kudryavtsev, V., Kvaratskheliya, T., La Thi, V. N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, D., Lambert, R. W., Lanciotti, E., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Gac, R. Le, van Leerdam, J., Lees, J. -P., Lefèvre, R., Leflat, A., Lefrançois, J., Leo, S., Leroy, O., Lesiak, T., Leverington, B., Li, Y., Gioi, L. Li, Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., Lohn, S., Longstaff, I., Lopes, J. H., Lopez-March, N., Lu, H., Lucchesi, D., Luisier, J., Luo, H., Machefert, F., Machikhiliyan, I. V., Maciuc, F., Maev, O., Malde, S., Manca, G., Mancinelli, G., Maratas, J., Marconi, U., Marino, P., Märki, R., Marks, J., Martellotti, G., Martens, A., Sánchez, A. Martín, Martinelli, M., Santos, D. Martinez, Tostes, D. Martins, Martynov, A., Massafferri, A., Matev, R., Mathe, Z., Matteuzzi, C., Maurice, E., Mazurov, A., McCarthy, J., McNab, A., McNulty, R., McSkelly, B., Meadows, B., Meier, F., Meissner, M., Merk, M., Milanes, D. A., Minard, M. -N., Rodriguez, J. Molina, Monteil, S., Moran, D., Morawski, P., Mordà, A., Morello, M. J., Mountain, R., Mous, I., Muheim, F., Müller, K., Muresan, R., Muryn, B., Muster, B., Naik, P., Nakada, T., Nandakumar, R., Nasteva, I., Needham, M., Neubert, S., Neufeld, N., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nicol, M., Niess, V., Niet, R., Nikitin, N., Nikodem, T., Nomerotski, A., Novoselov, A., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Ogilvy, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Pal, B. K., Palano, A., Palczewski, T., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C. J., Passaleva, G., Patel, G. D., Patel, M., Patrick, G. N., Patrignani, C., Pavel-Nicorescu, C., Alvarez, A. Pazos, Pellegrino, A., Penso, G., Altarelli, M. Pepe, Perazzini, S., Trigo, E. Perez, Yzquierdo, A. Pérez-Calero, Perret, P., Perrin-Terrin, M., Pescatore, L., Pesen, E., Petridis, K., Petrolini, A., Phan, A., Olloqui, E. Picatoste, Pietrzyk, B., Pilař, T., Pinci, D., Playfer, S., Casasus, M. Plo, Polci, F., Polok, G., Poluektov, A., Polycarpo, E., Popov, A., Popov, D., Popovici, B., Potterat, C., Powell, A., Prisciandaro, J., Pritchard, A., Prouve, C., Pugatch, V., Navarro, A. Puig, Punzi, G., Qian, W., Rademacker, J. H., Rakotomiaramanana, B., Rangel, M. S., Raniuk, I., Rauschmayr, N., Raven, G., Redford, S., Reid, M. M., Reis, A. C. dos, Ricciardi, S., Richards, A., Rinnert, K., Molina, V. Rives, Romero, D. A. Roa, Robbe, P., Roberts, D. A., Rodrigues, E., Perez, P. Rodriguez, Roiser, S., Romanovsky, V., Vidal, A. Romero, Rouvinet, J., Ruf, T., Ruffini, F., Ruiz, H., Valls, P. Ruiz, Sabatino, G., Silva, J. J. Saborido, Sagidova, N., Sail, P., Saitta, B., Guimaraes, V. Salustino, Sedes, B. Sanmartin, Sannino, M., Santacesaria, R., Rios, C. Santamarina, Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schindler, H., Schlupp, M., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M. -H., Schwemmer, R., Sciascia, B., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Sepp, I., Serra, N., Serrano, J., Seyfert, P., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Coutinho, R. Silva, Sirendi, M., Skidmore, N., Skwarnicki, T., Smith, N. A., Smith, E., Smith, J., Smith, M., Sokoloff, M. D., Soler, F. J. P., Soomro, F., Souza, D., De Paula, B. Souza, Spaan, B., Sparkes, A., Spradlin, P., Stagni, F., Stahl, S., Steinkamp, O., Stevenson, S., Stoica, S., Stone, S., Storaci, B., Straticiuc, M., Straumann, U., Subbiah, V. K., Sun, L., Swientek, S., Syropoulos, V., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Teklishyn, M., Teodorescu, E., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Tolk, S., Tonelli, D., Topp-Joergensen, S., Torr, N., Tournefier, E., Tourneur, S., Tran, M. T., Tresch, M., Tsaregorodtsev, A., Tsopelas, P., Tuning, N., Garcia, M. Ubeda, Ukleja, A., Urner, D., Ustyuzhanin, A., Uwer, U., Vagnoni, V., Valenti, G., Vallier, A., Van Dijk, M., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Velthuis, J. J., Veltri, M., Veneziano, G., Vesterinen, M., Viaud, B., Vieira, D., Vilasis-Cardona, X., Vollhardt, A., Volyanskyy, D., Voong, D., Vorobyev, A., Vorobyev, V., Voß, C., Voss, H., Waldi, R., Wallace, C., Wallace, R., Wandernoth, S., Wang, J., Ward, D. R., Watson, N. K., Webber, A. D., Websdale, D., Whitehead, M., Wicht, J., Wiechczynski, J., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M. P., Williams, M., Wilson, F. F., Wimberley, J., Wishahi, J., Wislicki, W., Witek, M., Wotton, S. A., Wright, S., Wu, S., Wyllie, K., Xie, Y., Xing, Z., Yang, Z., Young, R., Yuan, X., Yushchenko, O., Zangoli, M., Zavertyaev, M., Zhang, F., Zhang, L., Zhang, W. C., Zhang, Y., Zhelezov, A., Zhokhov, A., Zhong, L., and Zvyagin, A.

Subjects
High Energy Physics - Experiment
Abstract

First observation of the decay Bs -> D0bar phi is reported using pp collision data, corresponding to an integrated luminosity of 1.0 fb^-1, collected by the LHCb experiment at a centre-of-mass energy of 7 TeV. The significance of the signal is 6.2 standard deviations. The branching fraction is measured relative to that of the decay Bs -> D0bar K*0bar to be 0.069 +/- 0.013 (stat) +/- 0.007 (syst). The first measurement of the ratio of branching fractions for the decays Bs -> D0bar K*0bar and Bd->D0bar K*0 is found to be 7.8 +/- 0.7 (stat) +/- 0.3 (syst) +/- 0.6 (f_s/f_d), where the last uncertainty is due to the ratio of the Bs and Bd fragmentation fractions., Comment: Journal reference added

Published
2013
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44. The Electromagnetic Calorimeter for the T2K Near Detector ND280

Author

Allan, D., Andreopoulos, C., Angelsen, C., Barker, G. J., Barr, G., Bentham, S., Bertram, I., Boyd, S., Briggs, K., Calland, R. G., Carroll, J., Cartwright, S. L., Carver, A., Chavez, C., Christodoulou, G., Coleman, J., Cooke, P., Davies, G., Densham, C., Di Lodovico, F., Dobson, J., Duboyski, T., Durkin, T., Evans, D. L., Finch, A., Fitton, M., Gannaway, F. C., Grant, A., Grant, N., Grenwood, S., Guzowski, P., Hadley, D., Haigh, M., Harrison, P. F., Hatzikoutelis, A., Haycock, T. D. J., Hyndman, A., Ilic, J., Ives, S., Kaboth, A. C., Kasey, V., Kellet, L., Khaleeq, M., Kogan, G., Kormos, L. L., Lawe, M., Lawson, T. B., Lister, C., Litchfield, R. P., Lockwood, M., Malek, M., Maryon, T., Masliah, P., Mavrokoridis, K., McCauley, N., Mercer, I., Metelko, C., Morgan, B., Morris, J., Muir, A., Murdoch, M., Nicholls, T., Noy, M., O'Keeffe, H. M., Owen, R. A., Payne, D., Pearce, G. F., Perkin, J. D., Poplawska, E., Preece, R., Qian, W., Ratoff, P., Raufer, T., Raymond, M., Reeves, M., Richards, D., Rooney, M., Sacco, R., Sadler, S., Schaack, P., Scott, M., Scully, D. I., Short, S., Siyad, M., Smith, R., Still, B., Sutcliffe, P., Taylor, I. J., Terri, R., Thompson, L. F., Thorley, A., Thorpe, M., Timis, C., Touramanis, C., Uchida, M. A., Uchida, Y., Vacheret, A., VanSchalkwyk, J. F., Veledar, O., Waldron, A. V., Ward, M. A., Ward, G. P., Wark, D., Wascko, M. O., Weber, A., West, N., Whitehead, L. H., Wilkinson, C., and Wilson, J. R.

Subjects
Physics - Instrumentation and Detectors
Abstract

The T2K experiment studies oscillations of an off-axis muon neutrino beam between the J-PARC accelerator complex and the Super-Kamiokande detector. Special emphasis is placed on measuring the mixing angle theta_13 by observing electron neutrino appearance via the sub-dominant muon neutrino to electron neutrino oscillation, and searching for CP violation in the lepton sector. The experiment includes a sophisticated, off-axis, near detector, the ND280, situated 280 m downstream of the neutrino production target in order to measure the properties of the neutrino beam and to understand better neutrino interactions at the energy scale below a few GeV. The data collected with the ND280 are used to study charged- and neutral-current neutrino interaction rates and kinematics prior to oscillation, in order to reduce uncertainties in the oscillation measurements by the far detector. A key element of the near detector is the ND280 electromagnetic calorimeter (ECal), consisting of active scintillator bars sandwiched between lead sheets and read outwith multi-pixel photon counters (MPPCs). The ECal is vital to the reconstruction of neutral particles, and the identification of charged particle species. The ECal surrounds the Pi-0 detector (P0D) and the tracking region of the ND280, and is enclosed in the former UA1/NOMAD dipole magnet. This paper describes the design, construction and assembly of the ECal, as well as the materials from which it is composed. The electronic and data acquisition (DAQ) systems are discussed, and performance of the ECal modules, as deduced from measurements with particle beams, cosmic rays, the calibration system, and T2K data, is described., Comment: 45 pages, 29 PDF figures. This version is accepted for publication in JINST. It includes minor changes as recommended by the referee. In particular, a bit of further information and explanation is added to several sections

Published
2013
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45. Model-independent search for CP violation in D0 to K-K+pi-pi+ and D0 to pi-pi+pi+pi- decays

Author

LHCb collaboration, Aaij, R., Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves Jr, A. A., Amato, S., Amerio, S., Amhis, Y., Anderlini, L., Anderson, J., Andreassen, R., Andrews, J. E., Appleby, R. B., Gutierrez, O. Aquines, Archilli, F., Artamonov, A., Artuso, M., Aslanides, E., Auriemma, G., Baalouch, M., Bachmann, S., Back, J. J., Baesso, C., Balagura, V., Baldini, W., Barlow, R. J., Barschel, C., Barsuk, S., Barter, W., Bauer, Th., Bay, A., Beddow, J., Bedeschi, F., Bediaga, I., Belogurov, S., Belous, K., Belyaev, I., Ben-Haim, E., Bencivenni, G., Benson, S., Benton, J., Berezhnoy, A., Bernet, R., Bettler, M. -O., van Beuzekom, M., Bien, A., Bifani, S., Bird, T., Bizzeti, A., Bjørnstad, P. M., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bowcock, T. J. V., Bowen, E., Bozzi, C., Brambach, T., Brand, J. van den, Bressieux, J., Brett, D., Britsch, M., Britton, T., Brook, N. H., Brown, H., Burducea, I., Bursche, A., Busetto, G., Buytaert, J., Cadeddu, S., Callot, O., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Perez, D. Campora, Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carranza-Mejia, H., Carson, L., Akiba, K. Carvalho, Casse, G., Garcia, L. Castillo, Cattaneo, M., Cauet, Ch., Cenci, R., Charles, M., Charpentier, Ph., Chen, P., Chiapolini, N., Chrzaszcz, M., Ciba, K., Vidal, X. Cid, Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Coca, C., Coco, V., Cogan, J., Cogneras, E., Collins, P., Comerma-Montells, A., Contu, A., Cook, A., Coombes, M., Coquereau, S., Corti, G., Couturier, B., Cowan, G. A., Cowie, E., Craik, D. C., Cunliffe, S., Currie, R., D'Ambrosio, C., David, P., David, P. N. Y., Davis, A., De Bonis, I., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., De Paula, L., De Silva, W., De Simone, P., Decamp, D., Deckenhoff, M., Del Buono, L., Déléage, N., Derkach, D., Deschamps, O., Dettori, F., Di Canto, A., Dijkstra, H., Dogaru, M., Donleavy, S., Dordei, F., Suárez, A. Dosil, Dossett, D., Dovbnya, A., Dupertuis, F., Durante, P., Dzhelyadin, R., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisenhardt, S., Eitschberger, U., Ekelhof, R., Eklund, L., Rifai, I. El, Elsasser, Ch., Falabella, A., Färber, C., Fardell, G., Farinelli, C., Farry, S., Ferguson, D., Albor, V. Fernandez, Rodrigues, F. Ferreira, Ferro-Luzzi, M., Filippov, S., Fiore, M., Fitzpatrick, C., Fontana, M., Fontanelli, F., Forty, R., Francisco, O., Frank, M., Frei, C., Frosini, M., Furcas, S., Furfaro, E., Torreira, A. Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garofoli, J., Garosi, P., Tico, J. Garra, Garrido, L., Gaspar, C., Gauld, R., Gersabeck, E., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Giubega, L., Gligorov, V. V., Göbel, C., Golubkov, D., Golutvin, A., Gomes, A., Gorbounov, P., Gordon, H., Gotti, C., Gándara, M. Grabalosa, Diaz, R. Graciani, Cardoso, L. A. Granado, Graugés, E., Graziani, G., Grecu, A., Greening, E., Gregson, S., Griffith, P., Grünberg, O., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haines, S. C., Hall, S., Hamilton, B., Hampson, T., Hansmann-Menzemer, S., Harnew, N., Harnew, S. T., Harrison, J., Hartmann, T., He, J., Head, T., Heijne, V., Hennessy, K., Henrard, P., Morata, J. A. Hernando, van Herwijnen, E., Hess, M., Hicheur, A., Hicks, E., Hill, D., Hoballah, M., Hombach, C., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Hussain, N., Hutchcroft, D., Hynds, D., Iakovenko, V., Idzik, M., Ilten, P., Jacobsson, R., Jaeger, A., Jans, E., Jaton, P., Jawahery, A., Jing, F., John, M., Johnson, D., Jones, C. R., Joram, C., Jost, B., Kaballo, M., Kandybei, S., Kanso, W., Karacson, M., Karbach, T. M., Kenyon, I. R., Ketel, T., Keune, A., Khanji, B., Kochebina, O., Komarov, I., Koopman, R. F., Koppenburg, P., Korolev, M., Kozlinskiy, A., Kravchuk, L., Kreplin, K., Kreps, M., Krocker, G., Krokovny, P., Kruse, F., Kucharczyk, M., Kudryavtsev, V., Kurek, K., Kvaratskheliya, T., La Thi, V. N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, D., Lambert, R. W., Lanciotti, E., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Gac, R. Le, van Leerdam, J., Lees, J. -P., Lefèvre, R., Leflat, A., Lefrançois, J., Leo, S., Leroy, O., Lesiak, T., Leverington, B., Li, Y., Gioi, L. Li, Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., Lohn, S., Longstaff, I., Lopes, J. H., Lopez-March, N., Lu, H., Lucchesi, D., Luisier, J., Luo, H., Machefert, F., Machikhiliyan, I. V., Maciuc, F., Maev, O., Malde, S., Manca, G., Mancinelli, G., Maratas, J., Marconi, U., Marino, P., Märki, R., Marks, J., Martellotti, G., Martens, A., Sánchez, A. Martín, Martinelli, M., Santos, D. Martinez, Tostes, D. Martins, Martynov, A., Massafferri, A., Matev, R., Mathe, Z., Matteuzzi, C., Maurice, E., Mazurov, A., McCarthy, J., McNab, A., McNulty, R., McSkelly, B., Meadows, B., Meier, F., Meissner, M., Merk, M., Milanes, D. A., Minard, M. -N., Rodriguez, J. Molina, Monteil, S., Moran, D., Morawski, P., Mordà, A., Morello, M. J., Mountain, R., Mous, I., Muheim, F., Müller, K., Muresan, R., Muryn, B., Muster, B., Naik, P., Nakada, T., Nandakumar, R., Nasteva, I., Needham, M., Neubert, S., Neufeld, N., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nicol, M., Niess, V., Niet, R., Nikitin, N., Nikodem, T., Nomerotski, A., Novoselov, A., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Ogilvy, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Pal, B. K., Palano, A., Palczewski, T., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C. J., Passaleva, G., Patel, G. D., Patel, M., Patrick, G. N., Patrignani, C., Pavel-Nicorescu, C., Alvarez, A. Pazos, Pellegrino, A., Penso, G., Altarelli, M. Pepe, Perazzini, S., Trigo, E. Perez, Yzquierdo, A. Pérez-Calero, Perret, P., Perrin-Terrin, M., Pescatore, L., Pesen, E., Petridis, K., Petrolini, A., Phan, A., Olloqui, E. Picatoste, Pietrzyk, B., Pilař, T., Pinci, D., Playfer, S., Casasus, M. Plo, Polci, F., Polok, G., Poluektov, A., Polycarpo, E., Popov, A., Popov, D., Popovici, B., Potterat, C., Powell, A., Prisciandaro, J., Pritchard, A., Prouve, C., Pugatch, V., Navarro, A. Puig, Punzi, G., Qian, W., Rademacker, J. H., Rakotomiaramanana, B., Rangel, M. S., Raniuk, I., Rauschmayr, N., Raven, G., Redford, S., Reid, M. M., Reis, A. C. dos, Ricciardi, S., Richards, A., Rinnert, K., Molina, V. Rives, Romero, D. A. Roa, Robbe, P., Roberts, D. A., Rodrigues, E., Perez, P. Rodriguez, Roiser, S., Romanovsky, V., Vidal, A. Romero, Rouvinet, J., Ruf, T., Ruffini, F., Ruiz, H., Valls, P. Ruiz, Sabatino, G., Silva, J. J. Saborido, Sagidova, N., Sail, P., Saitta, B., Guimaraes, V. Salustino, Sedes, B. Sanmartin, Sannino, M., Santacesaria, R., Rios, C. Santamarina, Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schindler, H., Schlupp, M., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M. -H., Schwemmer, R., Sciascia, B., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Sepp, I., Serra, N., Serrano, J., Seyfert, P., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Coutinho, R. Silva, Sirendi, M., Skidmore, N., Skwarnicki, T., Smith, N. A., Smith, E., Smith, J., Smith, M., Sokoloff, M. D., Soler, F. J. P., Soomro, F., Souza, D., De Paula, B. Souza, Spaan, B., Sparkes, A., Spradlin, P., Stagni, F., Stahl, S., Steinkamp, O., Stevenson, S., Stoica, S., Stone, S., Storaci, B., Straticiuc, M., Straumann, U., Subbiah, V. K., Sun, L., Swientek, S., Syropoulos, V., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Teklishyn, M., Teodorescu, E., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Tolk, S., Tonelli, D., Topp-Joergensen, S., Torr, N., Tournefier, E., Tourneur, S., Tran, M. T., Tresch, M., Tsaregorodtsev, A., Tsopelas, P., Tuning, N., Garcia, M. Ubeda, Ukleja, A., Urner, D., Ustyuzhanin, A., Uwer, U., Vagnoni, V., Valenti, G., Vallier, A., Van Dijk, M., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Velthuis, J. J., Veltri, M., Veneziano, G., Vesterinen, M., Viaud, B., Vieira, D., Vilasis-Cardona, X., Vollhardt, A., Volyanskyy, D., Voong, D., Vorobyev, A., Vorobyev, V., Voß, C., Voss, H., Waldi, R., Wallace, C., Wallace, R., Wandernoth, S., Wang, J., Ward, D. R., Watson, N. K., Webber, A. D., Websdale, D., Whitehead, M., Wicht, J., Wiechczynski, J., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M. P., Williams, M., Wilson, F. F., Wimberley, J., Wishahi, J., Wislicki, W., Witek, M., Wotton, S. A., Wright, S., Wu, S., Wyllie, K., Xie, Y., Xing, Z., Yang, Z., Young, R., Yuan, X., Yushchenko, O., Zangoli, M., Zavertyaev, M., Zhang, F., Zhang, L., Zhang, W. C., Zhang, Y., Zhelezov, A., Zhokhov, A., Zhong, L., and Zvyagin, A.

Subjects
High Energy Physics - Experiment
Abstract

A search for CP violation in the phase-space structures of D0 and D0bar decays to the final states K-K+pi-pi+ and pi-pi+pi+pi- is presented. The search is carried out with a data set corresponding to an integrated luminosity of 1.0fb^-1 collected in 2011 by the LHCb experiment in $pp$ collisions at a centre-of-mass energy of 7TeV. For the K-K+pi-pi+ final state, the four-body phase space is divided into 32 bins, each bin with approximately 1800 decays. The p-value under the hypothesis of no CP violation is 9.1%, and in no bin is a CP asymmetry greater than 6.5% observed. The phase space of the pi-pi+pi+pi- final state is partitioned into 128 bins, each bin with approximately 2500 decays. The $p$-value under the hypothesis of no CP violation is 41%, and in no bin is a CP asymmetry greater than 5.5% observed. All results are consistent with the hypothesis of no CP violation at the current sensitivity., Comment: 13 pages, 5 figures

Published
2013
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46. Measurement of form-factor independent observables in the decay $B^{0} \to K^{*0} \mu^+ \mu^-$

Author

LHCb collaboration, Aaij, R., Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves Jr, A. A., Amato, S., Amerio, S., Amhis, Y., Anderlini, L., Anderson, J., Andreassen, R., Andrews, J. E., Appleby, R. B., Gutierrez, O. Aquines, Archilli, F., Artamonov, A., Artuso, M., Aslanides, E., Auriemma, G., Baalouch, M., Bachmann, S., Back, J. J., Baesso, C., Balagura, V., Baldini, W., Barlow, R. J., Barschel, C., Barsuk, S., Barter, W., Bauer, Th., Bay, A., Beddow, J., Bedeschi, F., Bediaga, I., Belogurov, S., Belous, K., Belyaev, I., Ben-Haim, E., Bencivenni, G., Benson, S., Benton, J., Berezhnoy, A., Bernet, R., Bettler, M. -O., van Beuzekom, M., Bien, A., Bifani, S., Bird, T., Bizzeti, A., Bjørnstad, P. M., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bowcock, T. J. V., Bowen, E., Bozzi, C., Brambach, T., Brand, J. van den, Bressieux, J., Brett, D., Britsch, M., Britton, T., Brook, N. H., Brown, H., Burducea, I., Bursche, A., Busetto, G., Buytaert, J., Cadeddu, S., Callot, O., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Perez, D. Campora, Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carranza-Mejia, H., Carson, L., Akiba, K. Carvalho, Casse, G., Garcia, L. Castillo, Cattaneo, M., Cauet, Ch., Cenci, R., Charles, M., Charpentier, Ph., Chen, P., Chiapolini, N., Chrzaszcz, M., Ciba, K., Vidal, X. Cid, Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Coca, C., Coco, V., Cogan, J., Cogneras, E., Collins, P., Comerma-Montells, A., Contu, A., Cook, A., Coombes, M., Coquereau, S., Corti, G., Couturier, B., Cowan, G. A., Craik, D. C., Cunliffe, S., Currie, R., D'Ambrosio, C., David, P., David, P. N. Y., Davis, A., De Bonis, I., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., De Paula, L., De Silva, W., De Simone, P., Decamp, D., Deckenhoff, M., Del Buono, L., Déléage, N., Derkach, D., Deschamps, O., Dettori, F., Di Canto, A., Dijkstra, H., Dogaru, M., Donleavy, S., Dordei, F., Suárez, A. Dosil, Dossett, D., Dovbnya, A., Dupertuis, F., Durante, P., Dzhelyadin, R., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisenhardt, S., Eitschberger, U., Ekelhof, R., Eklund, L., Rifai, I. El, Elsasser, Ch., Falabella, A., Färber, C., Fardell, G., Farinelli, C., Farry, S., Ferguson, D., Albor, V. Fernandez, Rodrigues, F. Ferreira, Ferro-Luzzi, M., Filippov, S., Fiore, M., Fitzpatrick, C., Fontana, M., Fontanelli, F., Forty, R., Francisco, O., Frank, M., Frei, C., Frosini, M., Furcas, S., Furfaro, E., Torreira, A. Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garofoli, J., Garosi, P., Tico, J. Garra, Garrido, L., Gaspar, C., Gauld, R., Gersabeck, E., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Giubega, L., Gligorov, V. V., Göbel, C., Golubkov, D., Golutvin, A., Gomes, A., Gorbounov, P., Gordon, H., Gotti, C., Gándara, M. Grabalosa, Diaz, R. Graciani, Cardoso, L. A. Granado, Graugés, E., Graziani, G., Grecu, A., Greening, E., Gregson, S., Griffith, P., Grünberg, O., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haines, S. C., Hall, S., Hamilton, B., Hampson, T., Hansmann-Menzemer, S., Harnew, N., Harnew, S. T., Harrison, J., Hartmann, T., He, J., Head, T., Heijne, V., Hennessy, K., Henrard, P., Morata, J. A. Hernando, van Herwijnen, E., Hess, M., Hicheur, A., Hicks, E., Hill, D., Hoballah, M., Hombach, C., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Hussain, N., Hutchcroft, D., Hynds, D., Iakovenko, V., Idzik, M., Ilten, P., Jacobsson, R., Jaeger, A., Jans, E., Jaton, P., Jawahery, A., Jing, F., John, M., Johnson, D., Jones, C. R., Joram, C., Jost, B., Kaballo, M., Kandybei, S., Kanso, W., Karacson, M., Karbach, T. M., Kenyon, I. R., Ketel, T., Keune, A., Khanji, B., Kochebina, O., Komarov, I., Koopman, R. F., Koppenburg, P., Korolev, M., Kozlinskiy, A., Kravchuk, L., Kreplin, K., Kreps, M., Krocker, G., Krokovny, P., Kruse, F., Kucharczyk, M., Kudryavtsev, V., Kurek, K., Kvaratskheliya, T., La Thi, V. N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, D., Lambert, R. W., Lanciotti, E., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Gac, R. Le, van Leerdam, J., Lees, J. -P., Lefèvre, R., Leflat, A., Lefrançois, J., Leo, S., Leroy, O., Lesiak, T., Leverington, B., Li, Y., Gioi, L. Li, Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., Lohn, S., Longstaff, I., Lopes, J. H., Lopez-March, N., Lu, H., Lucchesi, D., Luisier, J., Luo, H., Machefert, F., Machikhiliyan, I. V., Maciuc, F., Maev, O., Malde, S., Manca, G., Mancinelli, G., Maratas, J., Marconi, U., Marino, P., Märki, R., Marks, J., Martellotti, G., Martens, A., Sánchez, A. Martín, Martinelli, M., Santos, D. Martinez, Tostes, D. Martins, Martynov, A., Massafferri, A., Matev, R., Mathe, Z., Matteuzzi, C., Maurice, E., Mazurov, A., McCarthy, J., McNab, A., McNulty, R., McSkelly, B., Meadows, B., Meier, F., Meissner, M., Merk, M., Milanes, D. A., Minard, M. -N., Rodriguez, J. Molina, Monteil, S., Moran, D., Morawski, P., Mordà, A., Morello, M. J., Mountain, R., Mous, I., Muheim, F., Müller, K., Muresan, R., Muryn, B., Muster, B., Naik, P., Nakada, T., Nandakumar, R., Nasteva, I., Needham, M., Neubert, S., Neufeld, N., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nicol, M., Niess, V., Niet, R., Nikitin, N., Nikodem, T., Nomerotski, A., Novoselov, A., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Ogilvy, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Pal, B. K., Palano, A., Palczewski, T., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C. J., Passaleva, G., Patel, G. D., Patel, M., Patrick, G. N., Patrignani, C., Pavel-Nicorescu, C., Alvarez, A. Pazos, Pellegrino, A., Penso, G., Altarelli, M. Pepe, Perazzini, S., Trigo, E. Perez, Yzquierdo, A. Pérez-Calero, Perret, P., Perrin-Terrin, M., Pescatore, L., Pesen, E., Petridis, K., Petrolini, A., Phan, A., Olloqui, E. Picatoste, Pietrzyk, B., Pilař, T., Pinci, D., Playfer, S., Casasus, M. Plo, Polci, F., Polok, G., Poluektov, A., Polycarpo, E., Popov, A., Popov, D., Popovici, B., Potterat, C., Powell, A., Prisciandaro, J., Pritchard, A., Prouve, C., Pugatch, V., Navarro, A. Puig, Punzi, G., Qian, W., Rademacker, J. H., Rakotomiaramanana, B., Rangel, M. S., Raniuk, I., Rauschmayr, N., Raven, G., Redford, S., Reid, M. M., Reis, A. C. dos, Ricciardi, S., Richards, A., Rinnert, K., Molina, V. Rives, Romero, D. A. Roa, Robbe, P., Roberts, D. A., Rodrigues, E., Perez, P. Rodriguez, Roiser, S., Romanovsky, V., Vidal, A. Romero, Rouvinet, J., Ruf, T., Ruffini, F., Ruiz, H., Valls, P. Ruiz, Sabatino, G., Silva, J. J. Saborido, Sagidova, N., Sail, P., Saitta, B., Guimaraes, V. Salustino, Sedes, B. Sanmartin, Sannino, M., Santacesaria, R., Rios, C. Santamarina, Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schindler, H., Schlupp, M., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M. -H., Schwemmer, R., Sciascia, B., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Sepp, I., Serra, N., Serrano, J., Seyfert, P., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Coutinho, R. Silva, Sirendi, M., Skwarnicki, T., Smith, N. A., Smith, E., Smith, J., Smith, M., Sokoloff, M. D., Soler, F. J. P., Soomro, F., Souza, D., De Paula, B. Souza, Spaan, B., Sparkes, A., Spradlin, P., Stagni, F., Stahl, S., Steinkamp, O., Stevenson, S., Stoica, S., Stone, S., Storaci, B., Straticiuc, M., Straumann, U., Subbiah, V. K., Sun, L., Swientek, S., Syropoulos, V., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Teklishyn, M., Teodorescu, E., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Tolk, S., Tonelli, D., Topp-Joergensen, S., Torr, N., Tournefier, E., Tourneur, S., Tran, M. T., Tresch, M., Tsaregorodtsev, A., Tsopelas, P., Tuning, N., Garcia, M. Ubeda, Ukleja, A., Urner, D., Ustyuzhanin, A., Uwer, U., Vagnoni, V., Valenti, G., Vallier, A., Van Dijk, M., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Velthuis, J. J., Veltri, M., Veneziano, G., Vesterinen, M., Viaud, B., Vieira, D., Vilasis-Cardona, X., Vollhardt, A., Volyanskyy, D., Voong, D., Vorobyev, A., Vorobyev, V., Voß, C., Voss, H., Waldi, R., Wallace, C., Wallace, R., Wandernoth, S., Wang, J., Ward, D. R., Watson, N. K., Webber, A. D., Websdale, D., Whitehead, M., Wicht, J., Wiechczynski, J., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M. P., Williams, M., Wilson, F. F., Wimberley, J., Wishahi, J., Wislicki, W., Witek, M., Wotton, S. A., Wright, S., Wu, S., Wyllie, K., Xie, Y., Xing, Z., Yang, Z., Young, R., Yuan, X., Yushchenko, O., Zangoli, M., Zavertyaev, M., Zhang, F., Zhang, L., Zhang, W. C., Zhang, Y., Zhelezov, A., Zhokhov, A., Zhong, L., and Zvyagin, A.

Subjects
High Energy Physics - Experiment
Abstract

We present a measurement of form-factor independent angular observables in the decay \mbox{$B^0\to K^{*}(892)^{0}\mu^+ \mu^-$}. The analysis is based on a data sample corresponding to an integrated luminosity of 1.0fb$^{-1}$, collected by the LHCb experiment in $pp$ collisions at a center-of-mass energy of 7TeV. Four observables are measured in six bins of the dimuon invariant mass squared, $q^2$, in the range $0.1

Published
2013
Full Text
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47. First measurement of time-dependent CP violation in Bs -> K+K- decays

Author

LHCb collaboration, Aaij, R., Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves Jr, A. A., Amato, S., Amerio, S., Amhis, Y., Anderlini, L., Anderson, J., Andreassen, R., Andrews, J. E., Appleby, R. B., Gutierrez, O. Aquines, Archilli, F., Artamonov, A., Artuso, M., Aslanides, E., Auriemma, G., Baalouch, M., Bachmann, S., Back, J. J., Baesso, C., Balagura, V., Baldini, W., Barlow, R. J., Barschel, C., Barsuk, S., Barter, W., Bauer, Th., Bay, A., Beddow, J., Bedeschi, F., Bediaga, I., Belogurov, S., Belous, K., Belyaev, I., Ben-Haim, E., Bencivenni, G., Benson, S., Benton, J., Berezhnoy, A., Bernet, R., Bettler, M. -O., van Beuzekom, M., Bien, A., Bifani, S., Bird, T., Bizzeti, A., Bjørnstad, P. M., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bowcock, T. J. V., Bowen, E., Bozzi, C., Brambach, T., Brand, J. van den, Bressieux, J., Brett, D., Britsch, M., Britton, T., Brook, N. H., Brown, H., Burducea, I., Bursche, A., Busetto, G., Buytaert, J., Cadeddu, S., Callot, O., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Perez, D. Campora, Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carranza-Mejia, H., Carson, L., Akiba, K. Carvalho, Casse, G., Garcia, L. Castillo, Cattaneo, M., Cauet, Ch., Cenci, R., Charles, M., Charpentier, Ph., Chen, P., Chiapolini, N., Chrzaszcz, M., Ciba, K., Vidal, X. Cid, Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Coca, C., Coco, V., Cogan, J., Cogneras, E., Collins, P., Comerma-Montells, A., Contu, A., Cook, A., Coombes, M., Coquereau, S., Corti, G., Couturier, B., Cowan, G. A., Cowie, E., Craik, D. C., Cunliffe, S., Currie, R., D'Ambrosio, C., David, P., David, P. N. Y., Davis, A., De Bonis, I., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., De Paula, L., De Silva, W., De Simone, P., Decamp, D., Deckenhoff, M., Del Buono, L., Déléage, N., Derkach, D., Deschamps, O., Dettori, F., Di Canto, A., Dijkstra, H., Dogaru, M., Donleavy, S., Dordei, F., Suárez, A. Dosil, Dossett, D., Dovbnya, A., Dupertuis, F., Durante, P., Dzhelyadin, R., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisenhardt, S., Eitschberger, U., Ekelhof, R., Eklund, L., Rifai, I. El, Elsasser, Ch., Falabella, A., Färber, C., Fardell, G., Farinelli, C., Farry, S., Ferguson, D., Albor, V. Fernandez, Rodrigues, F. Ferreira, Ferro-Luzzi, M., Filippov, S., Fiore, M., Fitzpatrick, C., Fontana, M., Fontanelli, F., Forty, R., Francisco, O., Frank, M., Frei, C., Frosini, M., Furcas, S., Furfaro, E., Torreira, A. Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garofoli, J., Garosi, P., Tico, J. Garra, Garrido, L., Gaspar, C., Gauld, R., Gersabeck, E., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Giubega, L., Gligorov, V. V., Göbel, C., Golubkov, D., Golutvin, A., Gomes, A., Gorbounov, P., Gordon, H., Gotti, C., Gándara, M. Grabalosa, Diaz, R. Graciani, Cardoso, L. A. Granado, Graugés, E., Graziani, G., Grecu, A., Greening, E., Gregson, S., Griffith, P., Grünberg, O., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haines, S. C., Hall, S., Hamilton, B., Hampson, T., Hansmann-Menzemer, S., Harnew, N., Harnew, S. T., Harrison, J., Hartmann, T., He, J., Head, T., Heijne, V., Hennessy, K., Henrard, P., Morata, J. A. Hernando, van Herwijnen, E., Hess, M., Hicheur, A., Hicks, E., Hill, D., Hoballah, M., Hombach, C., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Hussain, N., Hutchcroft, D., Hynds, D., Iakovenko, V., Idzik, M., Ilten, P., Jacobsson, R., Jaeger, A., Jans, E., Jaton, P., Jawahery, A., Jing, F., John, M., Johnson, D., Jones, C. R., Joram, C., Jost, B., Kaballo, M., Kandybei, S., Kanso, W., Karacson, M., Karbach, T. M., Kenyon, I. R., Ketel, T., Keune, A., Khanji, B., Kochebina, O., Komarov, I., Koopman, R. F., Koppenburg, P., Korolev, M., Kozlinskiy, A., Kravchuk, L., Kreplin, K., Kreps, M., Krocker, G., Krokovny, P., Kruse, F., Kucharczyk, M., Kudryavtsev, V., Kurek, K., Kvaratskheliya, T., La Thi, V. N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, D., Lambert, R. W., Lanciotti, E., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Gac, R. Le, van Leerdam, J., Lees, J. -P., Lefèvre, R., Leflat, A., Lefrançois, J., Leo, S., Leroy, O., Lesiak, T., Leverington, B., Li, Y., Gioi, L. Li, Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., Lohn, S., Longstaff, I., Lopes, J. H., Lopez-March, N., Lu, H., Lucchesi, D., Luisier, J., Luo, H., Machefert, F., Machikhiliyan, I. V., Maciuc, F., Maev, O., Malde, S., Manca, G., Mancinelli, G., Maratas, J., Marconi, U., Marino, P., Märki, R., Marks, J., Martellotti, G., Martens, A., Sánchez, A. Martín, Martinelli, M., Santos, D. Martinez, Tostes, D. Martins, Martynov, A., Massafferri, A., Matev, R., Mathe, Z., Matteuzzi, C., Maurice, E., Mazurov, A., McCarthy, J., McNab, A., McNulty, R., McSkelly, B., Meadows, B., Meier, F., Meissner, M., Merk, M., Milanes, D. A., Minard, M. -N., Rodriguez, J. Molina, Monteil, S., Moran, D., Morawski, P., Mordà, A., Morello, M. J., Mountain, R., Mous, I., Muheim, F., Müller, K., Muresan, R., Muryn, B., Muster, B., Naik, P., Nakada, T., Nandakumar, R., Nasteva, I., Needham, M., Neubert, S., Neufeld, N., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nicol, M., Niess, V., Niet, R., Nikitin, N., Nikodem, T., Nomerotski, A., Novoselov, A., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Ogilvy, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Pal, B. K., Palano, A., Palczewski, T., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C. J., Passaleva, G., Patel, G. D., Patel, M., Patrick, G. N., Patrignani, C., Pavel-Nicorescu, C., Alvarez, A. Pazos, Pellegrino, A., Penso, G., Altarelli, M. Pepe, Perazzini, S., Trigo, E. Perez, Yzquierdo, A. Pérez-Calero, Perret, P., Perrin-Terrin, M., Pescatore, L., Pesen, E., Petridis, K., Petrolini, A., Phan, A., Olloqui, E. Picatoste, Pietrzyk, B., Pilař, T., Pinci, D., Playfer, S., Casasus, M. Plo, Polci, F., Polok, G., Poluektov, A., Polycarpo, E., Popov, A., Popov, D., Popovici, B., Potterat, C., Powell, A., Prisciandaro, J., Pritchard, A., Prouve, C., Pugatch, V., Navarro, A. Puig, Punzi, G., Qian, W., Rademacker, J. H., Rakotomiaramanana, B., Rangel, M. S., Raniuk, I., Rauschmayr, N., Raven, G., Redford, S., Reid, M. M., Reis, A. C. dos, Ricciardi, S., Richards, A., Rinnert, K., Molina, V. Rives, Romero, D. A. Roa, Robbe, P., Roberts, D. A., Rodrigues, E., Perez, P. Rodriguez, Roiser, S., Romanovsky, V., Vidal, A. Romero, Rouvinet, J., Ruf, T., Ruffini, F., Ruiz, H., Valls, P. Ruiz, Sabatino, G., Silva, J. J. Saborido, Sagidova, N., Sail, P., Saitta, B., Guimaraes, V. Salustino, Sedes, B. Sanmartin, Sannino, M., Santacesaria, R., Rios, C. Santamarina, Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schindler, H., Schlupp, M., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M. -H., Schwemmer, R., Sciascia, B., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Sepp, I., Serra, N., Serrano, J., Seyfert, P., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Coutinho, R. Silva, Sirendi, M., Skidmore, N., Skwarnicki, T., Smith, N. A., Smith, E., Smith, J., Smith, M., Sokoloff, M. D., Soler, F. J. P., Soomro, F., Souza, D., De Paula, B. Souza, Spaan, B., Sparkes, A., Spradlin, P., Stagni, F., Stahl, S., Steinkamp, O., Stevenson, S., Stoica, S., Stone, S., Storaci, B., Straticiuc, M., Straumann, U., Subbiah, V. K., Sun, L., Swientek, S., Syropoulos, V., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Teklishyn, M., Teodorescu, E., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Tolk, S., Tonelli, D., Topp-Joergensen, S., Torr, N., Tournefier, E., Tourneur, S., Tran, M. T., Tresch, M., Tsaregorodtsev, A., Tsopelas, P., Tuning, N., Garcia, M. Ubeda, Ukleja, A., Urner, D., Ustyuzhanin, A., Uwer, U., Vagnoni, V., Valenti, G., Vallier, A., Van Dijk, M., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Velthuis, J. J., Veltri, M., Veneziano, G., Vesterinen, M., Viaud, B., Vieira, D., Vilasis-Cardona, X., Vollhardt, A., Volyanskyy, D., Voong, D., Vorobyev, A., Vorobyev, V., Voß, C., Voss, H., Waldi, R., Wallace, C., Wallace, R., Wandernoth, S., Wang, J., Ward, D. R., Watson, N. K., Webber, A. D., Websdale, D., Whitehead, M., Wicht, J., Wiechczynski, J., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M. P., Williams, M., Wilson, F. F., Wimberley, J., Wishahi, J., Wislicki, W., Witek, M., Wotton, S. A., Wright, S., Wu, S., Wyllie, K., Xie, Y., Xing, Z., Yang, Z., Young, R., Yuan, X., Yushchenko, O., Zangoli, M., Zavertyaev, M., Zhang, F., Zhang, L., Zhang, W. C., Zhang, Y., Zhelezov, A., Zhokhov, A., Zhong, L., and Zvyagin, A.

Subjects
High Energy Physics - Experiment
Abstract

Direct and mixing-induced CP-violating asymmetries in Bs -> K+K- decays are measured for the first time using a data sample of pp collisions, corresponding to an integrated luminosity of 1.0 fb^{-1}, collected with the LHCb detector at a centre-of-mass energy of 7 TeV. The results are C_{KK} = 0.14 \pm 0.11 \pm 0.03 and S_{KK} = 0.30 \pm 0.12 \pm 0.04, where the first uncertainties are statistical and the second systematic. The corresponding quantities are also determined for B0 -> pi+pi- decays to be C_{pipi} = -0.38 \pm 0.15 \pm 0.02 and S_{pipi} = -0.71 \pm 0.13 \pm 0.02, in good agreement with existing measurements., Comment: 22 pages, 8 figures, 4 tables, v2 with minor changes after journal review

Published
2013
Full Text
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48. Measurement of the $C\P$ asymmetry in $B^+ \rightarrow K^+ \mu^+ \mu^-$ decays

Author

LHCb collaboration, Aaij, R., Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves Jr, A. A., Amato, S., Amerio, S., Amhis, Y., Anderlini, L., Anderson, J., Andreassen, R., Andrews, J. E., Appleby, R. B., Gutierrez, O. Aquines, Archilli, F., Artamonov, A., Artuso, M., Aslanides, E., Auriemma, G., Baalouch, M., Bachmann, S., Back, J. J., Baesso, C., Balagura, V., Baldini, W., Barlow, R. J., Barschel, C., Barsuk, S., Barter, W., Bauer, Th., Bay, A., Beddow, J., Bedeschi, F., Bediaga, I., Belogurov, S., Belous, K., Belyaev, I., Ben-Haim, E., Bencivenni, G., Benson, S., Benton, J., Berezhnoy, A., Bernet, R., Bettler, M. -O., van Beuzekom, M., Bien, A., Bifani, S., Bird, T., Bizzeti, A., Bjørnstad, P. M., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bowcock, T. J. V., Bowen, E., Bozzi, C., Brambach, T., Brand, J. van den, Bressieux, J., Brett, D., Britsch, M., Britton, T., Brook, N. H., Brown, H., Burducea, I., Bursche, A., Busetto, G., Buytaert, J., Cadeddu, S., Callot, O., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Perez, D. Campora, Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carranza-Mejia, H., Carson, L., Akiba, K. Carvalho, Casse, G., Garcia, L. Castillo, Cattaneo, M., Cauet, Ch., Cenci, R., Charles, M., Charpentier, Ph., Chen, P., Chiapolini, N., Chrzaszcz, M., Ciba, K., Vidal, X. Cid, Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Coca, C., Coco, V., Cogan, J., Cogneras, E., Collins, P., Comerma-Montells, A., Contu, A., Cook, A., Coombes, M., Coquereau, S., Corti, G., Couturier, B., Cowan, G. A., Cowie, E., Craik, D. C., Cunliffe, S., Currie, R., D'Ambrosio, C., David, P., David, P. N. Y., Davis, A., De Bonis, I., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., De Paula, L., De Silva, W., De Simone, P., Decamp, D., Deckenhoff, M., Del Buono, L., Déléage, N., Derkach, D., Deschamps, O., Dettori, F., Di Canto, A., Dijkstra, H., Dogaru, M., Donleavy, S., Dordei, F., Suárez, A. Dosil, Dossett, D., Dovbnya, A., Dupertuis, F., Durante, P., Dzhelyadin, R., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisenhardt, S., Eitschberger, U., Ekelhof, R., Eklund, L., Rifai, I. El, Elsasser, Ch., Falabella, A., Färber, C., Fardell, G., Farinelli, C., Farry, S., Ferguson, D., Albor, V. Fernandez, Rodrigues, F. Ferreira, Ferro-Luzzi, M., Filippov, S., Fiore, M., Fitzpatrick, C., Fontana, M., Fontanelli, F., Forty, R., Francisco, O., Frank, M., Frei, C., Frosini, M., Furcas, S., Furfaro, E., Torreira, A. Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garofoli, J., Garosi, P., Tico, J. Garra, Garrido, L., Gaspar, C., Gauld, R., Gersabeck, E., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Giubega, L., Gligorov, V. V., Göbel, C., Golubkov, D., Golutvin, A., Gomes, A., Gorbounov, P., Gordon, H., Gotti, C., Gándara, M. Grabalosa, Diaz, R. Graciani, Cardoso, L. A. Granado, Graugés, E., Graziani, G., Grecu, A., Greening, E., Gregson, S., Griffith, P., Grünberg, O., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haines, S. C., Hall, S., Hamilton, B., Hampson, T., Hansmann-Menzemer, S., Harnew, N., Harnew, S. T., Harrison, J., Hartmann, T., He, J., Head, T., Heijne, V., Hennessy, K., Henrard, P., Morata, J. A. Hernando, van Herwijnen, E., Hess, M., Hicheur, A., Hicks, E., Hill, D., Hoballah, M., Hombach, C., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Hussain, N., Hutchcroft, D., Hynds, D., Iakovenko, V., Idzik, M., Ilten, P., Jacobsson, R., Jaeger, A., Jans, E., Jaton, P., Jawahery, A., Jing, F., John, M., Johnson, D., Jones, C. R., Joram, C., Jost, B., Kaballo, M., Kandybei, S., Kanso, W., Karacson, M., Karbach, T. M., Kenyon, I. R., Ketel, T., Keune, A., Khanji, B., Kochebina, O., Komarov, I., Koopman, R. F., Koppenburg, P., Korolev, M., Kozlinskiy, A., Kravchuk, L., Kreplin, K., Kreps, M., Krocker, G., Krokovny, P., Kruse, F., Kucharczyk, M., Kudryavtsev, V., Kurek, K., Kvaratskheliya, T., La Thi, V. N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, D., Lambert, R. W., Lanciotti, E., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Gac, R. Le, van Leerdam, J., Lees, J. -P., Lefèvre, R., Leflat, A., Lefrançois, J., Leo, S., Leroy, O., Lesiak, T., Leverington, B., Li, Y., Gioi, L. Li, Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., Lohn, S., Longstaff, I., Lopes, J. H., Lopez-March, N., Lu, H., Lucchesi, D., Luisier, J., Luo, H., Machefert, F., Machikhiliyan, I. V., Maciuc, F., Maev, O., Malde, S., Manca, G., Mancinelli, G., Maratas, J., Marconi, U., Marino, P., Märki, R., Marks, J., Martellotti, G., Martens, A., Sánchez, A. Martín, Martinelli, M., Santos, D. Martinez, Tostes, D. Martins, Martynov, A., Massafferri, A., Matev, R., Mathe, Z., Matteuzzi, C., Maurice, E., Mazurov, A., McCarthy, J., McNab, A., McNulty, R., McSkelly, B., Meadows, B., Meier, F., Meissner, M., Merk, M., Milanes, D. A., Minard, M. -N., Rodriguez, J. Molina, Monteil, S., Moran, D., Morawski, P., Mordà, A., Morello, M. J., Mountain, R., Mous, I., Muheim, F., Müller, K., Muresan, R., Muryn, B., Muster, B., Naik, P., Nakada, T., Nandakumar, R., Nasteva, I., Needham, M., Neubert, S., Neufeld, N., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nicol, M., Niess, V., Niet, R., Nikitin, N., Nikodem, T., Nomerotski, A., Novoselov, A., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Ogilvy, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Pal, B. K., Palano, A., Palczewski, T., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C. J., Passaleva, G., Patel, G. D., Patel, M., Patrick, G. N., Patrignani, C., Pavel-Nicorescu, C., Alvarez, A. Pazos, Pellegrino, A., Penso, G., Altarelli, M. Pepe, Perazzini, S., Trigo, E. Perez, Yzquierdo, A. Pérez-Calero, Perret, P., Perrin-Terrin, M., Pescatore, L., Pesen, E., Petridis, K., Petrolini, A., Phan, A., Olloqui, E. Picatoste, Pietrzyk, B., Pilař, T., Pinci, D., Playfer, S., Casasus, M. Plo, Polci, F., Polok, G., Poluektov, A., Polycarpo, E., Popov, A., Popov, D., Popovici, B., Potterat, C., Powell, A., Prisciandaro, J., Pritchard, A., Prouve, C., Pugatch, V., Navarro, A. Puig, Punzi, G., Qian, W., Rademacker, J. H., Rakotomiaramanana, B., Rangel, M. S., Raniuk, I., Rauschmayr, N., Raven, G., Redford, S., Reid, M. M., Reis, A. C. dos, Ricciardi, S., Richards, A., Rinnert, K., Molina, V. Rives, Romero, D. A. Roa, Robbe, P., Roberts, D. A., Rodrigues, E., Perez, P. Rodriguez, Roiser, S., Romanovsky, V., Vidal, A. Romero, Rouvinet, J., Ruf, T., Ruffini, F., Ruiz, H., Valls, P. Ruiz, Sabatino, G., Silva, J. J. Saborido, Sagidova, N., Sail, P., Saitta, B., Guimaraes, V. Salustino, Sedes, B. Sanmartin, Sannino, M., Santacesaria, R., Rios, C. Santamarina, Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schindler, H., Schlupp, M., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M. -H., Schwemmer, R., Sciascia, B., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Sepp, I., Serra, N., Serrano, J., Seyfert, P., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Coutinho, R. Silva, Sirendi, M., Skidmore, N., Skwarnicki, T., Smith, N. A., Smith, E., Smith, J., Smith, M., Sokoloff, M. D., Soler, F. J. P., Soomro, F., Souza, D., De Paula, B. Souza, Spaan, B., Sparkes, A., Spradlin, P., Stagni, F., Stahl, S., Steinkamp, O., Stevenson, S., Stoica, S., Stone, S., Storaci, B., Straticiuc, M., Straumann, U., Subbiah, V. K., Sun, L., Swientek, S., Syropoulos, V., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Teklishyn, M., Teodorescu, E., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Tolk, S., Tonelli, D., Topp-Joergensen, S., Torr, N., Tournefier, E., Tourneur, S., Tran, M. T., Tresch, M., Tsaregorodtsev, A., Tsopelas, P., Tuning, N., Garcia, M. Ubeda, Ukleja, A., Urner, D., Ustyuzhanin, A., Uwer, U., Vagnoni, V., Valenti, G., Vallier, A., Van Dijk, M., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Velthuis, J. J., Veltri, M., Veneziano, G., Vesterinen, M., Viaud, B., Vieira, D., Vilasis-Cardona, X., Vollhardt, A., Volyanskyy, D., Voong, D., Vorobyev, A., Vorobyev, V., Voß, C., Voss, H., Waldi, R., Wallace, C., Wallace, R., Wandernoth, S., Wang, J., Ward, D. R., Watson, N. K., Webber, A. D., Websdale, D., Whitehead, M., Wicht, J., Wiechczynski, J., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M. P., Williams, M., Wilson, F. F., Wimberley, J., Wishahi, J., Wislicki, W., Witek, M., Wotton, S. A., Wright, S., Wu, S., Wyllie, K., Xie, Y., Xing, Z., Yang, Z., Young, R., Yuan, X., Yushchenko, O., Zangoli, M., Zavertyaev, M., Zhang, F., Zhang, L., Zhang, W. C., Zhang, Y., Zhelezov, A., Zhokhov, A., Zhong, L., and Zvyagin, A.

Subjects
High Energy Physics - Experiment
Abstract

A measurement of the $C\P$ asymmetry in $B^+ \rightarrow K^+ \mu^+ \mu^-$ decays is presented using $pp$ collision data, corresponding to an integrated luminosity of 1.0${\,fb}^{-1}$, recorded by the LHCb experiment during 2011 at a centre-of-mass energy of 7 TeV. The measurement is performed in seven bins of $\mu^+ \mu^-$ invariant mass squared in the range ${0.05

Published
2013
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49. Observation of $B^0_s$-$\bar{B}^0_s$ mixing and measurement of mixing frequencies using semileptonic B decays

Author

LHCb collaboration, Aaij, R., Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves Jr, A. A., Amato, S., Amerio, S., Amhis, Y., Anderlini, L., Anderson, J., Andreassen, R., Andrews, J. E., Andrianala, F., Appleby, R. B., Gutierrez, O. Aquines, Archilli, F., Artamonov, A., Artuso, M., Aslanides, E., Auriemma, G., Baalouch, M., Bachmann, S., Back, J. J., Baesso, C., Balagura, V., Baldini, W., Barlow, R. J., Barschel, C., Barsuk, S., Barter, W., Bauer, Th., Bay, A., Beddow, J., Bedeschi, F., Bediaga, I., Belogurov, S., Belous, K., Belyaev, I., Ben-Haim, E., Bencivenni, G., Benson, S., Benton, J., Berezhnoy, A., Bernet, R., Bettler, M. -O., van Beuzekom, M., Bien, A., Bifani, S., Bird, T., Bizzeti, A., Bjørnstad, P. M., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bowcock, T. J. V., Bowen, E., Bozzi, C., Brambach, T., Brand, J. van den, Bressieux, J., Brett, D., Britsch, M., Britton, T., Brook, N. H., Brown, H., Burducea, I., Bursche, A., Busetto, G., Buytaert, J., Cadeddu, S., Callot, O., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Perez, D. Campora, Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carranza-Mejia, H., Carson, L., Akiba, K. Carvalho, Casse, G., Garcia, L. Castillo, Cattaneo, M., Cauet, Ch., Cenci, R., Charles, M., Charpentier, Ph., Chen, P., Chiapolini, N., Chrzaszcz, M., Ciba, K., Vidal, X. Cid, Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Coca, C., Coco, V., Cogan, J., Cogneras, E., Collins, P., Comerma-Montells, A., Contu, A., Cook, A., Coombes, M., Coquereau, S., Corti, G., Couturier, B., Cowan, G. A., Craik, D. C., Cunliffe, S., Currie, R., D'Ambrosio, C., David, P., David, P. N. Y., Davis, A., De Bonis, I., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., De Paula, L., De Silva, W., De Simone, P., Decamp, D., Deckenhoff, M., Del Buono, L., Déléage, N., Derkach, D., Deschamps, O., Dettori, F., Di Canto, A., Dijkstra, H., Dogaru, M., Donleavy, S., Dordei, F., Suárez, A. Dosil, Dossett, D., Dovbnya, A., Dupertuis, F., Durante, P., Dzhelyadin, R., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisenhardt, S., Eitschberger, U., Ekelhof, R., Eklund, L., Rifai, I. El, Elsasser, Ch., Falabella, A., Färber, C., Fardell, G., Farinelli, C., Farry, S., Ferguson, D., Albor, V. Fernandez, Rodrigues, F. Ferreira, Ferro-Luzzi, M., Filippov, S., Fiore, M., Fitzpatrick, C., Fontana, M., Fontanelli, F., Forty, R., Francisco, O., Frank, M., Frei, C., Frosini, M., Furcas, S., Furfaro, E., Torreira, A. Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garofoli, J., Garosi, P., Tico, J. Garra, Garrido, L., Gaspar, C., Gauld, R., Gersabeck, E., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Giubega, L., Gligorov, V. V., Göbel, C., Golubkov, D., Golutvin, A., Gomes, A., Gorbounov, P., Gordon, H., Gotti, C., Gándara, M. Grabalosa, Diaz, R. Graciani, Cardoso, L. A. Granado, Graugés, E., Graziani, G., Grecu, A., Greening, E., Gregson, S., Griffith, P., Grünberg, O., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haines, S. C., Hall, S., Hamilton, B., Hampson, T., Hansmann-Menzemer, S., Harnew, N., Harnew, S. T., Harrison, J., Hartmann, T., He, J., Head, T., Heijne, V., Hennessy, K., Henrard, P., Morata, J. A. Hernando, van Herwijnen, E., Hess, M., Hicheur, A., Hicks, E., Hill, D., Hoballah, M., Hombach, C., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Hussain, N., Hutchcroft, D., Hynds, D., Iakovenko, V., Idzik, M., Ilten, P., Jacobsson, R., Jaeger, A., Jans, E., Jaton, P., Jawahery, A., Jing, F., John, M., Johnson, D., Jones, C. R., Joram, C., Jost, B., Kaballo, M., Kandybei, S., Kanso, W., Karacson, M., Karbach, T. M., Kenyon, I. R., Ketel, T., Keune, A., Khanji, B., Kochebina, O., Komarov, I., Koopman, R. F., Koppenburg, P., Korolev, M., Kozlinskiy, A., Kravchuk, L., Kreplin, K., Kreps, M., Krocker, G., Krokovny, P., Kruse, F., Kucharczyk, M., Kudryavtsev, V., Kurek, K., Kvaratskheliya, T., La Thi, V. N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, D., Lambert, R. W., Lanciotti, E., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Gac, R. Le, van Leerdam, J., Lees, J. -P., Lefèvre, R., Leflat, A., Lefrançois, J., Leo, S., Leroy, O., Lesiak, T., Leverington, B., Li, Y., Gioi, L. Li, Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., Lohn, S., Longstaff, I., Lopes, J. H., Lopez-March, N., Lu, H., Lucchesi, D., Luisier, J., Luo, H., Machefert, F., Machikhiliyan, I. V., Maciuc, F., Maev, O., Malde, S., Manca, G., Mancinelli, G., Maratas, J., Marconi, U., Marino, P., Märki, R., Marks, J., Martellotti, G., Martens, A., Sánchez, A. Martín, Martinelli, M., Santos, D. Martinez, Tostes, D. Martins, Martynov, A., Massafferri, A., Matev, R., Mathe, Z., Matteuzzi, C., Maurice, E., Mazurov, A., McCarthy, J., McNab, A., McNulty, R., McSkelly, B., Meadows, B., Meier, F., Meissner, M., Merk, M., Milanes, D. A., Minard, M. -N., Rodriguez, J. Molina, Monteil, S., Moran, D., Morawski, P., Mordà, A., Morello, M. J., Mountain, R., Mous, I., Muheim, F., Müller, K., Muresan, R., Muryn, B., Muster, B., Naik, P., Nakada, T., Nandakumar, R., Nasteva, I., Needham, M., Neubert, S., Neufeld, N., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nicol, M., Niess, V., Niet, R., Nikitin, N., Nikodem, T., Nomerotski, A., Novoselov, A., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Ogilvy, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Pal, B. K., Palano, A., Palczewski, T., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C. J., Passaleva, G., Patel, G. D., Patel, M., Patrick, G. N., Patrignani, C., Pavel-Nicorescu, C., Alvarez, A. Pazos, Pellegrino, A., Penso, G., Altarelli, M. Pepe, Perazzini, S., Trigo, E. Perez, Yzquierdo, A. Pérez-Calero, Perret, P., Perrin-Terrin, M., Pescatore, L., Pesen, E., Petridis, K., Petrolini, A., Phan, A., Olloqui, E. Picatoste, Pietrzyk, B., Pilař, T., Pinci, D., Playfer, S., Casasus, M. Plo, Polci, F., Polok, G., Poluektov, A., Polycarpo, E., Popov, A., Popov, D., Popovici, B., Potterat, C., Powell, A., Prisciandaro, J., Pritchard, A., Prouve, C., Pugatch, V., Navarro, A. Puig, Punzi, G., Qian, W., Rademacker, J. H., Rakotomiaramanana, B., Rangel, M. S., Raniuk, I., Rauschmayr, N., Raven, G., Redford, S., Reid, M. M., Reis, A. C. dos, Ricciardi, S., Richards, A., Rinnert, K., Molina, V. Rives, Romero, D. A. Roa, Robbe, P., Roberts, D. A., Rodrigues, E., Perez, P. Rodriguez, Roiser, S., Romanovsky, V., Vidal, A. Romero, Rouvinet, J., Ruf, T., Ruffini, F., Ruiz, H., Valls, P. Ruiz, Sabatino, G., Silva, J. J. Saborido, Sagidova, N., Sail, P., Saitta, B., Guimaraes, V. Salustino, Sedes, B. Sanmartin, Sannino, M., Santacesaria, R., Rios, C. Santamarina, Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schindler, H., Schlupp, M., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M. -H., Schwemmer, R., Sciascia, B., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Sepp, I., Serra, N., Serrano, J., Seyfert, P., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Coutinho, R. Silva, Sirendi, M., Skwarnicki, T., Smith, N. A., Smith, E., Smith, J., Smith, M., Sokoloff, M. D., Soler, F. J. P., Soomro, F., Souza, D., De Paula, B. Souza, Spaan, B., Sparkes, A., Spradlin, P., Stagni, F., Stahl, S., Steinkamp, O., Stevenson, S., Stoica, S., Stone, S., Storaci, B., Straticiuc, M., Straumann, U., Subbiah, V. K., Sun, L., Swientek, S., Syropoulos, V., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Teklishyn, M., Teodorescu, E., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Tolk, S., Tonelli, D., Topp-Joergensen, S., Torr, N., Tournefier, E., Tourneur, S., Tran, M. T., Tresch, M., Tsaregorodtsev, A., Tsopelas, P., Tuning, N., Garcia, M. Ubeda, Ukleja, A., Urner, D., Ustyuzhanin, A., Uwer, U., Vagnoni, V., Valenti, G., Vallier, A., Van Dijk, M., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Velthuis, J. J., Veltri, M., Veneziano, G., Vervink, K., Vesterinen, M., Viaud, B., Vieira, D., Vilasis-Cardona, X., Vollhardt, A., Volyanskyy, D., Voong, D., Vorobyev, A., Vorobyev, V., Voß, C., Voss, H., Waldi, R., Wallace, C., Wallace, R., Wandernoth, S., Wang, J., Ward, D. R., Watson, N. K., Webber, A. D., Websdale, D., Whitehead, M., Wicht, J., Wiechczynski, J., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M. P., Williams, M., Wilson, F. F., Wimberley, J., Wishahi, J., Wislicki, W., Witek, M., Wotton, S. A., Wright, S., Wu, S., Wyllie, K., Xie, Y., Xing, Z., Yang, Z., Young, R., Yuan, X., Yushchenko, O., Zangoli, M., Zavertyaev, M., Zhang, F., Zhang, L., Zhang, W. C., Zhang, Y., Zhelezov, A., Zhokhov, A., Zhong, L., and Zvyagin, A.

Subjects
High Energy Physics - Experiment
Abstract

The $B^0_s$ and $B^0$ mixing frequencies, $\Delta m_s$ and $\Delta m_d$, are measured using a data sample corresponding to an integrated luminosity of 1.0 fb^{-1} collected by the LHCb experiment in $pp$ collisions at a centre of mass energy of 7 TeV during 2011. Around 1.8x10^6 candidate events are selected of the type $B^0_{(s)} \to D^-_{(s)} \mu^+$ (+ anything), where about half are from peaking and combinatorial backgrounds. To determine the B decay times, a correction is required for the momentum carried by missing particles, which is performed using a simulation-based statistical method. Associated production of muons or mesons allows us to tag the initial-state flavour and so to resolve oscillations due to mixing. We obtain \Delta m_s = (17.93 \pm 0.22 (stat) \pm 0.15 (syst)) ps^{-1}, \Delta m_d = (0.503 \pm 0.011 (stat) \pm 0.013 (syst)) ps^{-1}. The hypothesis of no oscillations is rejected by the equivalent of 5.8 standard deviations for $B^0_s$ and 13.0 standard deviations for $B^0$. This is the first observation of $B^0_s$ mixing to be made using only semileptonic decays.

Published
2013
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50. Branching fraction and CP asymmetry of the decays $B^+ \to K_{\rm \scriptscriptstyle S}^0 \pi^+$ and $B^+ \to K_{\rm \scriptscriptstyle S}^0 K^+$

Author

LHCb collaboration, Aaij, R., Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves Jr, A. A., Amato, S., Amerio, S., Amhis, Y., Anderlini, L., Anderson, J., Andreassen, R., Andrews, J. E., Appleby, R. B., Gutierrez, O. Aquines, Archilli, F., Artamonov, A., Artuso, M., Aslanides, E., Auriemma, G., Baalouch, M., Bachmann, S., Back, J. J., Baesso, C., Balagura, V., Baldini, W., Barlow, R. J., Barschel, C., Barsuk, S., Barter, W., Bauer, Th., Bay, A., Beddow, J., Bedeschi, F., Bediaga, I., Belogurov, S., Belous, K., Belyaev, I., Ben-Haim, E., Bencivenni, G., Benson, S., Benton, J., Berezhnoy, A., Bernet, R., Bettler, M. -O., van Beuzekom, M., Bien, A., Bifani, S., Bird, T., Bizzeti, A., Bjørnstad, P. M., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bowcock, T. J. V., Bowen, E., Bozzi, C., Brambach, T., Brand, J. van den, Bressieux, J., Brett, D., Britsch, M., Britton, T., Brook, N. H., Brown, H., Burducea, I., Bursche, A., Busetto, G., Buytaert, J., Cadeddu, S., Callot, O., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Perez, D. Campora, Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carranza-Mejia, H., Carson, L., Akiba, K. Carvalho, Casse, G., Garcia, L. Castillo, Cattaneo, M., Cauet, Ch., Cenci, R., Charles, M., Charpentier, Ph., Chen, P., Chiapolini, N., Chrzaszcz, M., Ciba, K., Vidal, X. Cid, Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Coca, C., Coco, V., Cogan, J., Cogneras, E., Collins, P., Comerma-Montells, A., Contu, A., Cook, A., Coombes, M., Coquereau, S., Corti, G., Couturier, B., Cowan, G. A., Craik, D. C., Cunliffe, S., Currie, R., D'Ambrosio, C., David, P., David, P. N. Y., Davis, A., De Bonis, I., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., De Paula, L., De Silva, W., De Simone, P., Decamp, D., Deckenhoff, M., Del Buono, L., Déléage, N., Derkach, D., Deschamps, O., Dettori, F., Di Canto, A., Dijkstra, H., Dogaru, M., Donleavy, S., Dordei, F., Suárez, A. Dosil, Dossett, D., Dovbnya, A., Dupertuis, F., Durante, P., Dzhelyadin, R., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisenhardt, S., Eitschberger, U., Ekelhof, R., Eklund, L., Rifai, I. El, Elsasser, Ch., Falabella, A., Färber, C., Fardell, G., Farinelli, C., Farry, S., Ferguson, D., Albor, V. Fernandez, Rodrigues, F. Ferreira, Ferro-Luzzi, M., Filippov, S., Fiore, M., Fitzpatrick, C., Fontana, M., Fontanelli, F., Forty, R., Francisco, O., Frank, M., Frei, C., Frosini, M., Furcas, S., Furfaro, E., Torreira, A. Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garofoli, J., Garosi, P., Tico, J. Garra, Garrido, L., Gaspar, C., Gauld, R., Gersabeck, E., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Giubega, L., Gligorov, V. V., Göbel, C., Golubkov, D., Golutvin, A., Gomes, A., Gorbounov, P., Gordon, H., Gotti, C., Gándara, M. Grabalosa, Diaz, R. Graciani, Cardoso, L. A. Granado, Graugés, E., Graziani, G., Grecu, A., Greening, E., Gregson, S., Griffith, P., Grünberg, O., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haines, S. C., Hall, S., Hamilton, B., Hampson, T., Hansmann-Menzemer, S., Harnew, N., Harnew, S. T., Harrison, J., Hartmann, T., He, J., Head, T., Heijne, V., Hennessy, K., Henrard, P., Morata, J. A. Hernando, van Herwijnen, E., Hess, M., Hicheur, A., Hicks, E., Hill, D., Hoballah, M., Hombach, C., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Hussain, N., Hutchcroft, D., Hynds, D., Iakovenko, V., Idzik, M., Ilten, P., Jacobsson, R., Jaeger, A., Jans, E., Jaton, P., Jawahery, A., Jing, F., John, M., Johnson, D., Jones, C. R., Joram, C., Jost, B., Kaballo, M., Kandybei, S., Kanso, W., Karacson, M., Karbach, T. M., Kenyon, I. R., Ketel, T., Keune, A., Khanji, B., Kochebina, O., Komarov, I., Koopman, R. F., Koppenburg, P., Korolev, M., Kozlinskiy, A., Kravchuk, L., Kreplin, K., Kreps, M., Krocker, G., Krokovny, P., Kruse, F., Kucharczyk, M., Kudryavtsev, V., Kvaratskheliya, T., La Thi, V. N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, D., Lambert, R. W., Lanciotti, E., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Gac, R. Le, van Leerdam, J., Lees, J. -P., Lefèvre, R., Leflat, A., Lefrançois, J., Leo, S., Leroy, O., Lesiak, T., Leverington, B., Li, Y., Gioi, L. Li, Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., Lohn, S., Longstaff, I., Lopes, J. H., Lopez-March, N., Lu, H., Lucchesi, D., Luisier, J., Luo, H., Machefert, F., Machikhiliyan, I. V., Maciuc, F., Maev, O., Malde, S., Manca, G., Mancinelli, G., Maratas, J., Marconi, U., Marino, P., Märki, R., Marks, J., Martellotti, G., Martens, A., Sánchez, A. Martín, Martinelli, M., Santos, D. Martinez, Tostes, D. Martins, Martynov, A., Massafferri, A., Matev, R., Mathe, Z., Matteuzzi, C., Maurice, E., Mazurov, A., McCarthy, J., McNab, A., McNulty, R., McSkelly, B., Meadows, B., Meier, F., Meissner, M., Merk, M., Milanes, D. A., Minard, M. -N., Rodriguez, J. Molina, Monteil, S., Moran, D., Morawski, P., Mordà, A., Morello, M. J., Mountain, R., Mous, I., Muheim, F., Müller, K., Muresan, R., Muryn, B., Muster, B., Naik, P., Nakada, T., Nandakumar, R., Nasteva, I., Needham, M., Neubert, S., Neufeld, N., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nicol, M., Niess, V., Niet, R., Nikitin, N., Nikodem, T., Nomerotski, A., Novoselov, A., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Ogilvy, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Pal, B. K., Palano, A., Palczewski, T., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C. J., Passaleva, G., Patel, G. D., Patel, M., Patrick, G. N., Patrignani, C., Pavel-Nicorescu, C., Alvarez, A. Pazos, Pellegrino, A., Penso, G., Altarelli, M. Pepe, Perazzini, S., Trigo, E. Perez, Yzquierdo, A. Pérez-Calero, Perret, P., Perrin-Terrin, M., Pescatore, L., Pesen, E., Petridis, K., Petrolini, A., Phan, A., Olloqui, E. Picatoste, Pietrzyk, B., Pilař, T., Pinci, D., Playfer, S., Casasus, M. Plo, Polci, F., Polok, G., Poluektov, A., Polycarpo, E., Popov, A., Popov, D., Popovici, B., Potterat, C., Powell, A., Prisciandaro, J., Pritchard, A., Prouve, C., Pugatch, V., Navarro, A. Puig, Punzi, G., Qian, W., Rademacker, J. H., Rakotomiaramanana, B., Rangel, M. S., Raniuk, I., Rauschmayr, N., Raven, G., Redford, S., Reid, M. M., Reis, A. C. dos, Ricciardi, S., Richards, A., Rinnert, K., Molina, V. Rives, Romero, D. A. Roa, Robbe, P., Roberts, D. A., Rodrigues, E., Perez, P. Rodriguez, Roiser, S., Romanovsky, V., Vidal, A. Romero, Rouvinet, J., Ruf, T., Ruffini, F., Ruiz, H., Valls, P. Ruiz, Sabatino, G., Silva, J. J. Saborido, Sagidova, N., Sail, P., Saitta, B., Guimaraes, V. Salustino, Sedes, B. Sanmartin, Sannino, M., Santacesaria, R., Rios, C. Santamarina, Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schindler, H., Schlupp, M., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M. -H., Schwemmer, R., Sciascia, B., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Sepp, I., Serra, N., Serrano, J., Seyfert, P., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Coutinho, R. Silva, Sirendi, M., Skidmore, N., Skwarnicki, T., Smith, N. A., Smith, E., Smith, J., Smith, M., Sokoloff, M. D., Soler, F. J. P., Soomro, F., Souza, D., De Paula, B. Souza, Spaan, B., Sparkes, A., Spradlin, P., Stagni, F., Stahl, S., Steinkamp, O., Stevenson, S., Stoica, S., Stone, S., Storaci, B., Straticiuc, M., Straumann, U., Subbiah, V. K., Sun, L., Swientek, S., Syropoulos, V., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Teklishyn, M., Teodorescu, E., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Tolk, S., Tonelli, D., Topp-Joergensen, S., Torr, N., Tournefier, E., Tourneur, S., Tran, M. T., Tresch, M., Tsaregorodtsev, A., Tsopelas, P., Tuning, N., Garcia, M. Ubeda, Ukleja, A., Urner, D., Ustyuzhanin, A., Uwer, U., Vagnoni, V., Valenti, G., Vallier, A., Van Dijk, M., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Velthuis, J. J., Veltri, M., Veneziano, G., Vesterinen, M., Viaud, B., Vieira, D., Vilasis-Cardona, X., Vollhardt, A., Volyanskyy, D., Voong, D., Vorobyev, A., Vorobyev, V., Voß, C., Voss, H., Waldi, R., Wallace, C., Wallace, R., Wandernoth, S., Wang, J., Ward, D. R., Watson, N. K., Webber, A. D., Websdale, D., Whitehead, M., Wicht, J., Wiechczynski, J., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M. P., Williams, M., Wilson, F. F., Wimberley, J., Wishahi, J., Wislicki, W., Witek, M., Wotton, S. A., Wright, S., Wu, S., Wyllie, K., Xie, Y., Xing, Z., Yang, Z., Young, R., Yuan, X., Yushchenko, O., Zangoli, M., Zavertyaev, M., Zhang, F., Zhang, L., Zhang, W. C., Zhang, Y., Zhelezov, A., Zhokhov, A., Zhong, L., and Zvyagin, A.

Subjects
High Energy Physics - Experiment
Abstract

An analysis of $B^+ \to K_{\rm \scriptscriptstyle S}^0 \pi^+$ and $B^+ \to K_{\rm \scriptscriptstyle S}^0 K^+$ decays is performed with the LHCb experiment. The $pp$ collision data used correspond to integrated luminosities of $1{\,fb}^{-1}$ and $2{\,fb}^{-1}$ collected at centre-of-mass energies of $\sqrt{s}=7\mathrm{\,Te\kern -0.1em V}$ and $\sqrt{s}=8\mathrm{\,Te\kern -0.1em V}$, respectively. The ratio of branching fractions and the direct {\it CP} asymmetries are measured to be $\mathcal{B}(B^+ \to K_{\rm \scriptscriptstyle S}^0 K^+)/\mathcal{B}(B^+ \to K_{\rm \scriptscriptstyle S}^0 \pi^+) = 0.064 \pm 0.009\textrm{(stat.)} \pm 0.004\textrm{(syst.)}$, $\mathcal{A}^{\it CP}(B^+ \to K_{\rm \scriptscriptstyle S}^0 \pi^+) = -0.022 \pm 0.025\textrm{(stat.)} \pm 0.010\textrm{(syst.)}$ and $\mathcal{A}^{\it CP}(B^+ \to K_{\rm \scriptscriptstyle S}^0 K^+) = -0.21 \pm 0.14\textrm{(stat.)} \pm 0.01\textrm{(syst.)}$. The data sample taken at $\sqrt{s}=7\mathrm{\,Te\kern -0.1em V}$ is used to search for $B_c^+ \to K_{\rm \scriptscriptstyle S}^0 K^+$ decays and results in the upper limit $(f_c\cdot\mathcal{B}(B_c^+ \to K_{\rm \scriptscriptstyle S}^0 K^+))/(f_u\cdot\mathcal{B}(B^+ \to K_{\rm \scriptscriptstyle S}^0 \pi^+)) < 5.8\times10^{-2}\textrm{at 90% confidence level}$, where $f_c$ and $f_u$ denote the hadronisation fractions of a $\bar{b}$ quark into a $B_c^+$ or a $B^+$ meson, respectively., Comment: 13 pages, 2 figures

Published
2013
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