796 results on '"Schön M"'
Search Results
2. Terahertz spin currents and inverse spin Hall effect in thin-film heterostructures containing complex magnetic compounds
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Seifert, T., Martens, U., Günther, S., Schoen, M. A. W., Radu, F., Chen, X. Z., Lucas, I., Ramos, R., Aguirre, M. H., Algarabel, P. A., Anadón, A., Körner, H., Walowski, J., Back, C., Ibarra, M. R., Morellón, L., Saitoh, E., Wolf, M., Song, C., Uchida, K., Münzenberg, M., Radu, I., and Kampfrath, T.
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Condensed Matter - Materials Science ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Terahertz emission spectroscopy of ultrathin multilayers of magnetic and heavy metals has recently attracted much interest. This method not only provides fundamental insights into photoinduced spin transport and spin-orbit interaction at highest frequencies but has also paved the way to applications such as efficient and ultrabroadband emitters of terahertz electromagnetic radiation. So far, predominantly standard ferromagnetic materials have been exploited. Here, by introducing a suitable figure of merit, we systematically compare the strength of terahertz emission from X/Pt bilayers with X being a complex ferro-, ferri- and antiferromagnetic metal, that is, dysprosium cobalt (DyCo$_5$), gadolinium iron (Gd$_{24}$Fe$_{76}$), Magnetite (Fe$_3$O$_4$) and iron rhodium (FeRh). We find that the performance in terms of spin-current generation not only depends on the spin polarization of the magnet's conduction electrons but also on the specific interface conditions, thereby suggesting terahertz emission spectroscopy to be a highly surface-sensitive technique. In general, our results are relevant for all applications that rely on the optical generation of ultrafast spin currents in spintronic metallic multilayers.
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- 2017
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3. The temperature dependence of FeRh's transport properties
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Mankovsky, S., Polesya, S., Chadova, K., Ebert, H., Staunton, J. B., Gruenbaum, T., Schoen, M. A. W., Back, C. H., Chen, X. Z., and Song, C.
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Condensed Matter - Materials Science - Abstract
The finite-temperature transport properties of FeRh compounds are investigated by first-principles Density Functional Theory-based calculations. The focus is on the behavior of the longitudinal resistivity with rising temperature, which exhibits an abrupt decrease at the metamagnetic transition point, $T = T_m$ between ferro- and antiferromagnetic phases. A detailed electronic structure investigation for $T \geq 0$ K explains this feature and demonstrates the important role of (i) the difference of the electronic structure at the Fermi level between the two magnetically ordered states and (ii) the different degree of thermally induced magnetic disorder in the vicinity of $T_m$, giving different contributions to the resistivity. To support these conclusions, we also describe the temperature dependence of the spin-orbit induced anomalous Hall resistivity and Gilbert damping parameter. For the various response quantities considered the impact of thermal lattice vibrations and spin fluctuations on their temperature dependence is investigated in detail. Comparison with corresponding experimental data finds in general a very good agreement.
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- 2016
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4. Improving Contrast Enhancement in Pulmonary CTA: The value of breathing maneuvers
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Manava, P., Galster, M., Schoen, M., Ficker, J., Lell, M.M., Adamus, R., and Bruch, M.
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- 2020
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5. Versorgungsrealität der stationären vasoaktiven Therapie mit Prostazyklinderivaten bei Patienten mit akralen Durchblutungsstörungen bei systemischer Sklerose in Deutschland
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Juche, A., Siegert, E., Mueller-Ladner, U., Riemekasten, G., Günther, C., Kötter, I., Henes, J., Blank, N., Voll, R. E., Ehrchen, J., Schmalzing, M., Susok, L., Schmeiser, T., Sunderkoetter, C., Distler, J., Worm, M., Kreuter, A., Horváth, O. N., Schön, M. P., Korsten, P., Zeidler, G., Pfeiffer, C., Krieg, T., Hunzelmann, N., and Moinzadeh, P.
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- 2020
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6. Max Weber-Gesamtausgabe: Band II/7,1: Briefe 1911-1912
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Max Weber, Birgit Rudhard, Manfred Schön, M. Rainer Lepsius, Wolfgang J. Mommsen and Max Weber, Birgit Rudhard, Manfred Schön, M. Rainer Lepsius, Wolfgang J. Mommsen
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- 2019
7. Depletion potentials near geometrically structured substrates
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Bryk, P., Roth, R., Schoen, M., and Dietrich, S.
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Condensed Matter - Soft Condensed Matter - Abstract
Using the recently developed so-called White Bear version of Rosenfeld's Fundamental Measure Theory we calculate the depletion potentials between a hard-sphere colloidal particle in a solvent of small hard spheres and simple models of geometrically structured substrates: a right-angled wedge or edge. In the wedge geometry, there is a strong attraction beyond the corresponding one near a planar wall that significantly influences the structure of colloidal suspensions in wedges. In accordance with an experimental study, for the edge geometry we find a free energy barrier of the order of several $k_B T$ which repels a big colloidal particle from the edge., Comment: 7 pages, 7 figures
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- 2003
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8. Patientenverfügungen aus Sicht des chirurgischen Patienten – neue Aspekte und Ziele: Einstellungen und Verbreitungsgrad vorsorglicher Willensbekundungen von Patienten vor geplanten Operationen
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Justinger, C., Lang, T., Serrano Contreras, T., Schreiner, M., Kehl, F., and Schön, M. R.
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- 2019
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9. Prognostic Factors in Overall Survival of Patients with Unresectable Intrahepatic Cholangiocarcinoma Treated by Means of Yttrium-90 Radioembolization: Results in Therapy-Naïve Patients
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Reimer, P., Virarkar, M. K., Binnenhei, M., Justinger, M., Schön, M. R., and Tatsch, K.
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- 2018
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10. Supplementation-Induced Change in Muscle Carnosine is Paralleled by Changes in Muscle Metabolism, Protein Glycation and Reactive Carbonyl Species Sequestering
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SCHÖN, M, primary, JUST, I, additional, KRUMPOLEC, P, additional, BLAŽÍČEK, P, additional, VALKOVIČ, L, additional, ALDINI, G, additional, TSAI, C-L, additional, DE COURTEN, B, additional, KRŠŠÁK, M, additional, UKROPCOVÁ, B, additional, and UKROPEC, J, additional
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- 2023
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11. Effects of running on adiponectin, insulin and cytokines in cerebrospinal fluid in healthy young individuals
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Schön, M., Kovaničová, Z., Košutzká, Z., Nemec, M., Tomková, M., Jacková, L., Máderová, D., Slobodová, L., Valkovič, P., Ukropec, J., and Ukropcová, B.
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- 2019
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12. Scoring system for assessing the symmetry of tooth development in mixed dentition
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Friedrich, RE., primary and Schön, M., additional
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- 2023
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13. Wasted leg syndrome: An atypical slowly-progressive form of lower motor neuron disease
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Schön, M., primary, Oliveira Santos, M., additional, Gromicho, M., additional, Pinto, S., additional, Swash, M., additional, and de Carvalho, M., additional
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- 2023
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14. Laparoskopische Leberchirurgie
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Schön, M. R. and Justinger, C.
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- 2017
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15. Neutrophil extracellular traps: protagonists of cancer progression?
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Erpenbeck, L and Schön, M P
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- 2017
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16. Rolle des Integrins αE(CD103)β7 auf epidermotropen T-Lymphozyten in psoriatischen Läsionen und in einem T-Zell-vermittelten murinen Psoriasis-Modell
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Schön, M. P., Donohue, J. P., Schön, M., Pauls, K., Agace, W. W., Ruzicka, Th., Parker, Ch. M., Plettenberg, A., editor, Meigel, Wilhelm N., editor, and Moll, Ingrid, editor
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- 2000
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17. Swen Malte John zum 60. Geburtstag
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Frosch, P. J., Skudlik, C., and Schön, M. P.
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- 2017
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18. Pathogenese der Psoriasis vulgaris
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Schäkel, K., Schön, M. P., and Ghoreschi, K.
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- 2016
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19. Use of Preoperative Magnetic Resonance Imaging to Select Patients with Rectal Cancer for Neoadjuvant Chemoradiation—Interim Analysis of the German OCUM Trial (NCT01325649)
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Kreis, Martin E., Ruppert, R., Ptok, H., Strassburg, J., Brosi, P., Lewin, A., Schön, M. R., Sauer, J., Junginger, T., Merkel, S., Hermanek, P., and for the OCUM study group
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- 2016
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20. Cutaneous Lymphocyte Localization in the Pathogenesis of Psoriasis
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Schön, M. P., Stock, G., editor, Lessl, M., editor, Hamann, Alf, editor, Asadullah, Khusru, editor, and Schottelius, Arndt, editor
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- 2004
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21. Supplement to: Primary and secondary syphilis.
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Schön, M P and Bertsch, H P.
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- 2016
22. Gestaltung und Unterstützung von Communities of Practice
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Schoen, M. S. Stefan, Scheer, August-Wilhelm, editor, Markus, Ursula, editor, and Wagner, Daniel, editor
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- 1999
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23. Makulonoduläre Läsion am Rücken eines 66-jährigen Mannes
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Hartmann, F., Haenssle, H. A., Seitz, C. S., Kretschmer, L., Schön, M. P., and Buhl, T.
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- 2016
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24. Critical depletion of pure fluids in colloidal solids: Results of experiments on EURECA and grand canonical Monte Carlo simulations
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Thommes, M., Schoen, M., Findenegg, G. H., Araki, H., editor, Brézin, E., editor, Ehlers, J., editor, Frisch, U., editor, Hepp, K., editor, Jaffe, R. L., editor, Kippenhahn, R., editor, Weidenmüller, H. A., editor, Wess, J., editor, Zittartz, J., editor, Beiglböck, W., editor, Ratke, Lorenz, editor, Walter, Hannes, editor, and Feuerbacher, Berndt, editor
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- 1996
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25. Möglichkeiten der interdisziplinären Zusammenarbeit
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Biemer, E., Stock, W., Dielert, E., Partecke, B. D., Berger, A., Mailänder, P., Machens, H.-G., Rieck, B., Hierner, R., Feller, A.-M., Baumeister, R. G. H., Frick, A., Gabka, J. C., Bohmert, H., Schaller, P., Gabka, C. J., Maiwald, G., Götz, G., Liebeskind, U., Schön, M., Kilpert, B., Schlag, P. M., Rueger, J. M., Linhart, W., Gutt, C., Rosenthal, M., Hainbuch, V., Rückert, J., Pannike, A., Hartel, W., editor, and Hierholzer, G.
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- 1995
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26. TLR7 and TLR8 as targets in cancer therapy
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Schön, M P and Schön, M
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- 2008
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27. Fat depot-specific mRNA expression of novel loci associated with waist–hip ratio
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Schleinitz, D, Klöting, N, Lindgren, C M, Breitfeld, J, Dietrich, A, Schön, M R, Lohmann, T, Dreßler, M, Stumvoll, M, McCarthy, M I, Blüher, M, and Kovacs, P
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- 2014
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28. A numerical procedure to calculate residual stresses and fatigue life of pressurized components after autofrettage
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Schön, M., Köttgen, V. B., Seeger, T., Rie, K.-T., editor, Grünling, H. W., editor, König, G., editor, Neumann, P., editor, Nowack, H., editor, Schwalbe, K.-H., editor, and Seeger, T., editor
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- 1992
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29. The impact of stapling technique and surgeon specialism on anastomotic failure after right-sided colorectal resection: an international multicentre, prospective audit
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Glasbey, Jc, Nepogodiev, D, Battersby, N, Bhangu, A, El-Hussuna, A, Frasson, M, Singh, B, Vennix, S, Zmora, O, Pinkney, T, Chaudhri, S, Bemelman, W, Christensen, P, D'Hoore, A, Laurberg, S, Morton, D, Rubbini, M, Vaizey, C, Mehta, S, Ives, N, Magill, L, Perry, R, Sheward, N, Cillo, M, Estefania, D, Patron Uriburu, J, Ruiz, H, Salomon, M, Makhmudov, A, Selnyahina, L, Varabei, A, Vizhynis, Y, Claeys, D, Defoort, B, Muysoms, F, Pletinckx, P, Vergucht, V, Debergh, I, Feryn, T, Reusens, H, Nachtergaele, M, Francart, D, Jehaes, C, Markiewicz, S, Monami, B, Weerts, J, Bouckaert, W, Houben, B, Knol, J, Sergeant, G, Vangertruyden, G, Haeck, L, Lange, C, Sommeling, C, Vindevoghel, K, Castro, S, De Bruyn, H, Huyghe, M, De Wolf, E, Reynders, D, de Buck van Overstraeten, A, Wolthuis, A, Delibegovic, S, Christiani, A, Marchiori, M Jr, Rocha de Moraes, C, Tercioti, V Jr, Arabadjieva, E, Bulanov, D, Dardanov, D, Stoyanov, V, Yonkov, A, Angelov, K, Maslyankov, S, Sokolov, M, Todorov, G, Toshev, S, Georgiev, Y, Karashmalakov, A, Zafirov, G, Wang, X, Condic, D, Kraljik, D, Mrkovic, H, Pavkovic, V, Raguž, K, Bencurik, V, Holášková, E, Skrovina, M, Farkašová, M, Grolich, T, Kala, Z, Antos, F, Pruchova, V, Sotona, O, Chobola, M, Dusek, T, Ferko, A, Örhalmi, J, Hoch, J, Kocian, P, Martinek, L, Bernstein, I, Gotschalck Sunesen, K, Leunbach, J, Thorlacius-Ussing, O, Uth Oveson, A, Dahl Chirstensen, S, Gamez, V, Oeting, M, Schou Loeve, U, Ugianskis, A, Jessen, M, Krarup, P, Linde, K, Mirza, Q, Overgaard Stovring, J, Erritzøe, L, Loft Jakobsen, H, Lykke, J, Palmgren Colov, E, Husted Madsen, A, Linde Friis, T, Amstrup Funder, J, Dich, R, Kjaer, S, Rasmussen, S, Schlesinger, N, Dilling Kjaer, M, Qvist, N, Khalid, A, Ali, G, Hadi, S, Rosell Walker, L, Kivelä, A, Lehtonen, T, Lepistö, A, Scheinin, T, Siironen, P, Kössi, J, Kuusanmäki, P, Tomminen, T, Turunen, A, Rautio, T, Vierimaa, M, Huhtinen, H, Karvonen, J, Lavonius, M, Rantala, A, Varpe, P, Cotte, E, Francois, Y, Glehen, O, Kepenekian, V, Passot, G, Maggiori, L, Manceau, G, Panis, Y, Gout, M, Rullier, E, van Geluwe, B, Chafai, N, Lefevre, Jh, Parc, Y, Tiret, E, Couette, C, Duchalais, E, Agha, A, Hornberger, M, Hungbauer, A, Iesalnieks, I, Weindl, I, Crescenti, F, Keller, M, Kolodziejski, N, Scherer, R, Sterzing, D, Bock, B, Boehm, G, El-Magd, M, Krones, C, Niewiera, M, Buhr, J, Cordesmeyer, S, Hoffmann, M, Krückemeier, K, Vogel, T, Schön, M, Baral, J, Lukoschek, T, Münch, S, Pullig, F, Horisberger, K, Kienle, P, Magdeburg, J, Post, S, Batzalexis, K, Germanos, S, Agalianos, C, Dervenis, C, Gouvas, N, Kanavidis, P, Kottikias, A, Katsoulis, Ie, Korkolis, D, Plataniotis, G, Sakorafas, G, Akrida, I, Argentou, M, Kollatos, C, Lampropoulos, C, Tsochatzis, S, Besznyák, I, Bursics, A, Egyed, T, Papp, G, Svastics, I, Atladottir, J, Möller, P, Sigurdsson, H, Stefánsson, T, Valsdottir, E, Andrews, E, Foley, N, Hechtl, D, Majeed, M, Mccourt, M, Hanly, A, Hyland, J, Martin, S, O'Connell, Pr, Winter, D, Connelly, T, Joyce, W, Wrafter, P, Berkovitz, R, Avital, S, Haj Yahia, I, Hermann, N, Shpitz, B, White, I, Lishtzinsky, Y, Tsherniak, A, Wasserberg, N, Horesh, N, Keler, U, Pery, R, Shapiro, R, Tulchinsky, H, Badran, B, Dayan, K, Iskhakov, A, Lecaros, J, Nabih, N, Angrima, I, Bardini, R, Pizzolato, E, Tonello, M, Arces, F, Balestri, R, Ceccarelli, C, Prosperi, V, Rossi, E, Giannini, I, Vincenti, L, Di Candido, F, Di Iena, M, Guglielmi, A, Caputi-Iambrenghi, O, Marsanic, P, Mellano, A, Muratore, A, Annecchiarico, M, Bencini, L, Amore Bonapasta, S, Coratti, A, Guerra, F, Asteria, Cr, Boccia, L, Gerard, L, Pascariello, A, Manca, G, Marino, F, Casaril, A, Inama, M, Moretto, G, Bacchelli, C, Carvello, M, Mariani, N, Montorsi, M, Spinelli, A, Romairone, E, Scabini, S, Belli, A, Bianco, F, De Franciscis, S, Maria Romano, G, Delrio, P, Pace, U, Rega, D, Sassaroli, C, Scala, D, De Luca, R, Ruggieri, E, Elbetti, C, Garzi, A, Romoli, L, Scatizzi, M, Vannucchi, A, Curletti, G, Durante, V, Galleano, R, Mariani, F, Reggiani, L, Bellomo, R, Infantino, A, Franceschilli, L, Sileri, P, Clementi, I, Coletta, D, La Torre, F, Mingoli, A, Velluti, F, Di Giacomo, A, Fiorot, A, Massani, M, Padoan, L, Ruffolo, C, Caruso, S, Franceschini, F, Laessig, R, Monaci, I, Rontini, M, Annunziata Azienda SM, De Nardi, P, Elmore, U, Lemma, M, Rosati, R, Tamburini, A, De Luca, M, Sartori, A, Benevento, A, Bottini, C, Ferrari, Cc, Pata, F, Tessera, G, Pellino, G, Selvaggi, F, Lanzani, A, Romano, F, Sgroi, G, Steccanella, F, Turati, L, Yamamoto, T, Ancans, G, Gerkis, S, Leja, M, Pcolkins, A, Sivins, A, Latkauskas, T, Lizdenis, P, Saladžinskas, Ž, Švagždys, S, Tamelis, A, Razbadauskas, A, Sokolovas, M, Dulskas, A, Samalavicius, N, Jotautas, V, Mikalauskas, S, Poskus, E, Poskus, T, Strupas, K, Camenzuli, C, Cini, C, Predrag, A, Psaila, J, Spiteri, N, Buskens, C, de Groof EJ, Gooszen, J, Tanis, P, Belgers, E, Davids, P, Furnee, E, Postma, E, Pronk, A, Smakman, N, Clermonts, S, Zimmerman, D, Omloo, J, van der Zaag, E, van Duijvendijk, P, Wassenaar, E, Bruijninckx, M, de Graff, E, Doornebosch, P, Tetteroo, G, Vermaas, M, Iordens, G, Knops, S, Toorenvliet, B, van Westereenen HL, Boerma, E, Coene, P, van der Harst, E, Van Der Pool, A, Raber, M, Melenhorst, J, de Castro, S, Gerhards, M, Arron, M, Bremers, A, de Wilt, H, Ferenschild, F, Yauw, S, Cense, H, Demirkiran, A, Hunfeld, M, Mulder, I, Nonner, J, Swank, H, van Wagensveld, B, Bolmers, M, Briel, J, van Geloven, A, van Rossem, C, Klemann, V, Konsten, J, Leenders, B, Schok, T, Bleeker, W, Gidwani, A, Lawther, R, Loughlin, P, Skelly, B, Spence, R, Brun, M, Helgeland, M, Ignjatovic, D, Øresland, T, Yousefi, P, Flåten Backe, I, Helmer Sjo, O, Nesbakken, A, Tandberg-Eriksen, M, Cais, A, Hallvard Traeland, J, Herikstad, R, Kørner, H, Lauvland, N, Jajtner, D, Kabiesz, W, Rak, M, Gmerek, L, Horbacka, K, Horst, N, Krokowicz, P, Kwiatkowski, A, Pasnik, K, Karcz, P, Romaniszyn, M, Rusek, T, Walega, P, Czarencki, R, Obuszko, Z, Sitarska, M, Wojciech, W, Zawadzki, M, Amado, S, Clara, P, Couceiro, A, Malaquias, R, Rama, N, Almeida, A, Barbosa, E, Cernadas, E, Duarte, A, Silva, P, Costa, S, Martinez Insua, C, Marques, R, Pereira, J, Pereira, C, Sacchetti, M, Carvalho Pinto, B, Jorge Vieira Sousa, P, Oliveira, A, Cardoso, R, Carlos, S, Corte-Real, J, Moniz Pereira, P, Souto, R, Carneiro, C, Marinho, R, Nunes, V, Rocha, R, Sousa, M, Leite, J, Melo, F, Pimentel, J, Ventura, L, Vila Nova, C, Copăescu, C, Bintintan, V, Ciuce, C, Dindelegan, G, Scurtu, R, Seicean, R, Domansky, N, Karachun, A, Moiseenko, A, Pelipas, Y, Petrov, A, Pravosudov, I, Aiupov, R, Akmalov, Y, Parfenov, A, Suleymanov, N, Tarasov, N, Jumabaev, H, Mamedli, Z, Rasulov, A, Aliev, I, Chernikovskiy, I, Kochnev, V, Komyak, K, Smirnov, A, Achkasov, S, Bolikhov, K, Shelygin, Y, Sushkov, O, Zapolskiy, A, Gvozdenovic, M, Jovanovic, D, Lausevic, Z, Cvetković, D, Maravić, M, Milovanovic, B, Stojakovic, N, Tripković, I, Mihajlovic, D, Nestorovic, M, Pecic, V, Petrovic, D, Stanojevic, G, Barisic, G, Dimitrijevic, I, Krivokapic, Z, Markovic, V, Popovic, M, Aleksic, A, Dabic, D, Kostic, I, Milojkovic, A, Perunicic, V, Lukic, D, Petrovic, T, Radovanovic, D, Radovanovic, Z, Cuk, Vm, Cuk, Vv, Kenic, M, Kovacevic, B, Krdzic, I, Korcek, J, Rems, M, Toplak, J, Escarrâ, J, Gil Barrionuevo, M, Golda, T, Kreisler Moreno, E, Zerpa Martin, C, Álvarez Laso, C, Cumplido, P, Padin, H, Baixauli Fons, J, Hernández-Lizoain, J, Martinez-Ortega, P, Molina-Fernández, M, Sánchez-Justicia, C, Antonio Gracia Solanas, J, Córdoba Díaz de Laspra, E, Echazarreta-Gallego, E, Elia-Guedea, M, Ramirez, J, Arredondo Chaves, J, Diez González, P, Elosua, T, Sahagún, J, Turienzo Frade, A, Álvarez Conde, J, Castrillo, E, Diaz Maag, R, Maderuelo, V, Saldarriaga, L, Aldrey Cao, I, Fernández Varela, X, Núñez Fernández, S, Parajó Calvo, A, Villar Álvarez, S, Blesa Sierra, I, Lozano, R, Márquez, M, Porcel, O, Menendez, P, Fernández Hevia, M, Flores Sigüenza, L, Jimenez Toscano, M, Lacy Fortuny, A, Ordoñez Trujillo, J, Espi, A, Garcia-Botello, S, Martín-Arévalo, J, Moro-Valdezate, D, Pla-Martí, V, Blanco-Antona, F, Abrisqueta, J, Ibañez Canovas, N, Lujan Mompean, J, Escolá Ripoll, D, Martinez Gonzalez, S, Parodi, J, Fernández López, A, Ramos Fernández, M, Castellvi Valls, J, Ortiz de Zarate, L, Ribas, R, Sabia, D, Viso, L, Alonso Gonçalves, S, José Gil Egea, M, Pascual Damieta, M, Pera, M, Salvans Ruiz, S, Bernal, J, Landete, F, Ais, G, Etreros, J, Aguiló Lucia, J, Boscá, A, Deusa, S, García Del Caño, J, Viciano, V, García-Armengol, J, Roig, J, Blas, J, Escartin, J, Fatás, J, Fernando, J, Ferrer, R, Arias Pacheco, R, García Flórez, L, Moreno Gijón, M, Otero Díez, J, Solar Garcia, L, Aguilar Teixido, F, Balaguer Ojo, C, Bargallo Berzosa, J, Lamas Moure, S, Enrique Sierra, J, Fermiñán, A, Herrerias, F, Rufas, M, Viñas, J, Codina-Cazador, A, Farrés, R, Gómez, N, Julià, D, Planellas, P, López, J, Luna, A, Maristany, C, Muñoz Duyos, A, Puértolas, N, Alcantara Moral, M, Serra-Aracil, X, Concheiro Coello, 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R., Sánchez De La Villa, G., Compañ, A., García Marín, A., Nofuentes, C., Orts Micó, F., Pérez Auladell, V., Carrasco, M., Duque Perez, C., Gálvez-Pastor, S., Navarro Garcia, I., Sanchez Perez, A., Enjuto, D., Manuel Bujalance, F., Marcelin, N., Pérez, M., Serrano García, R., Cabrera, A., de la Portilla, F., Diaz-Pavon, J., Jimenez-Rodriguez, R., Vazquez-Monchul, J., Daza González, J., Gómez Pérez, R., Rivera Castellano, J., Roldán de la Rua, J., Errasti Alustiza, J., Fernandez, L., Romeo Ramirez, J., Sardon Ramos, J., Cermeño Toral, B., Alias, D., Garcia-Olmo, D., Guadalajara, H., Herreros, M., Pacheco, P., del Castillo Díez, F., Lima Pinto, F., Martínez Alegre, J., Ortega, I., Picardo Nieto Antonio, A., Caro, A., Escuder, J., Feliu, F., Millan, M., Alos Company, R., Frangi Caregnato, A., Lozoya Trujillo, R., Rodríguez Carrillo, R., Ruiz Carmona, M., Alonso, N., Ambrona Zafra, D., Amilka Ayala Candia, B., Bonnin Pascual, J., Pineño Flores, C., Alcazar Montero, J., Angoso Clavijo, M., Garcia, J., Sanchez Tocino, J., Gómez-Alcazar, C., Costa-Navarro, D., Ferri-Romero, J., Rey-Riveiro, M., Romero-Simó, M., Arencibia, B., Esclapez, P., García-Granero, E., Granero, P., Medina Fernández, F. J., Gallardo Herrera, A. B., Diaz López, C., Navarro Rodriguez, E., Torres Tordera, E., Arenal, J., Citores, M., Marcos, J., Sánchez, J., Tinoco, C., Espin, E., Garcia Granero, A., Jimenez Gomez, L., Sanchez Garcia, J., Vallribera, F., Folkesson, J., Sköldberg, F., Bergman, K., Borgström, E., Frey, J., Silfverberg, A., Söderholm, M., Nygren, J., Segelman, J., Gustafsson, D., Lagerqvist, A., Papp, A., Pelczar, M., Abraham-Nordling, M., Ahlberg, M., Sjovall, A., Tengstrom, J., Hagman, K., Chabok, A., Ezra, E., Nikberg, M., Smedh, K., Tiselius, C., Al-Naimi, N., Dao Duc, M., Meyer, J., Mormont, M., Ris, F., Prevost, G., Villiger, P., Hoffmann, H., Kettelhack, C., Kirchhoff, P., Oertli, D., Weixler, B., Aytac, B., Leventoglu, S., Mentes, B., Yuksel, O., Demirbas, S., Busra Ozkan, B., Selçuk Özbalci, G., Sungurtekin, U., Gülcü, B., Ozturk, E., Yilmazlar, T., Challand, C., Fearnhead, N., Hubbard, R., Kumar, S., Arthur, J., Barben, C., Skaife, P., Slawik, S., Williams, M., Zammit, M., Barker, J., French, J., Sarantitis, I., Slawinski, C., Clifford, R., Eardley, N., Johnson, M., Mcfaul, C., Vimalachandran, D., Allan, S., Bell, A., Oates, E., Shanmugam, V., Brigic, A., Halls, M., Pucher, P., Stubbs, B., Agarwal, T., Chopada, A., Mallappa, S., Pathmarajah, M., Sugden, C., Brown, C., Macdonald, E., Mckay, A., Richards, J., Robertson, A., Kaushal, M., Patel, P., Tezas, S., Touqan, N., Ayaani, S., Marimuthu, K., Piramanayagam, B., Vourvachis, M., Iqbal, N., Korsgen, S., Seretis, C., Shariff, U., Arnold, S., Chan, H., Clark, E., Fernandes, R., Moran, B., Bajwa, A., Mcarthur, D., Cao, K., Cunha, P., Pardoe, H., Quddus, A., Theodoropoulou, K., Bolln, C., Denys, G., Gillespie, M., Manimaran, N., Reidy, J., Malik, A. I., Malik, A., Pitt, J., Aryal, K., El-Hadi, A., Lal, R., Pal, A., Velchuru, V., Oliveira Cunha, M., Thomas, M., Bains, S., Boyle, K., Miller, A., Norwood, M., Yeung, J., Goian, L., Gurjar, S., Saghir, W., Sengupta, N., Stewart-Parker, E., Bailey, S., Khalil, T., Lawes, D., Nikolaou, S., Omar, G., Church, R., Muthiah, B., Garrett, W., Marsh, P., Obeid, N., Chandler, S., Coyne, P., Evans, M., Hunt, L., Lim, J., Oliphant, Z., Papworth, E., Weaver, H., Cuiñas Leon, K., Williams, G., Hernon, J., Kapur, S., Moosvi, R., Shaikh, I., Swafe, L., Aslam, M., Evans, J., Ihedioha, U., Kang, P., Merchant, J., Hompes, R., Middleton, R., Broomfield, A., Crutten-Wood, D., Foster, J., Nash, G., Akhtar, M., Boshnaq, M., Eldesouky, S., Mangam, S., Rabie, M., Ahmed, J., Khan, J., Ming Goh, N., Shamali, A., Stefan, S., Thompson, C., Amin, A., Docherty, J., Lim, M., Walker, K., Watson, A., Hossack, M., Mackenzie, N., Paraoan, M., Alam, N., Daniels, I., Narang, S., Pathak, S., Smart, N., Al-Qaddo, A., Codd, R., Rutka, O., Bronder, C., Crighton, I., Davies, E., Raymond, T., Bookless, L., Griffiths, B., Plusa, S., Carlson, G., Harrison, R., Lees, N., Mason, C., Quayle, J., Branagan, G., Broadhurst, J., Chave, H., Sleight, S., Awad, F., Cruickshank, N., Joy, H., Boereboom, C., Daliya, P., Dhillon, A., Watson, N., Watson, R., Artioukh, D., Gokul, K., Javed, M., Kong, R., Sutton, J., Faiz, O., Jenkins, I., Leo, C. A., Samaranayake, S. F., Warusavitarne, J., Arya, S., Bhan, C., Mukhtar, H., Oshowo, A., Wilson, J., Duff, S., Fatayer, T., Mbuvi, J., Sharma, A., Cornish, J., Davies, L., Harries, R., Morris, C., Torkington, J., Knight, J., Lai, C., Shihab, O., Tzivanakis, A., Hussain, A., Luke, D., Padwick, R., Torrance, A., Tsiamis, A., Dawson, P., Balfour, A., Brady, R., Mander, J., Paterson, H., Chandratreya, N., Chu, H., Cutting, J., Vernon, S., Wai Ho, C., Andreani, S., Patel, H., Warner, M., Yan Qi Tan, J., Iqbal, A., Khan, A., Perrin, K., Raza, A., Tan, S., Meyer, Jérémy, Graduate School, TOBB ETÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, TOBB ETU, Faculty of Medicine, Department of Surgical Sciences, and Demirbaş, Sezai
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Crohn’s disease ,Male ,Leak ,Surgi-cal technique ,anastomotic leak ,Bowel anastomosis ,colorectal cancer ,Crohn's disease ,epidemiology ,international ,oversewn ,stapler ,surgery ,surgical technique ,Colorectal cancer ,medicine.medical_treatment ,030230 surgery ,Colon/surgery ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,0302 clinical medicine ,Epidemiology ,Prospective Studies ,Treatment Failure ,Young adult ,Prospective cohort study ,Colectomy ,Aged, 80 and over ,General Surgery/statistics & numerical data ,Medical Audit ,ddc:617 ,Anastomosis, Surgical ,Gastroenterology ,Middle Aged ,Colorectal Neoplasms/surgery ,Colorectal surgery ,030220 oncology & carcinogenesis ,Female ,Colectomy/adverse effects ,Colorectal Neoplasms ,Anastomotic Leak/etiology ,Adult ,medicine.medical_specialty ,Adolescent ,Colon ,bowel anastomosis ,Colorectal Surgery/statistics & numerical data ,Anastomosis ,NO ,Young Adult ,03 medical and health sciences ,Surgical Stapling ,medicine ,Humans ,Aged ,ta3126 ,business.industry ,Anastomosis, Surgical/adverse effects ,Surgical Stapling/adverse effects ,Bowel anastomosi ,medicine.disease ,Surgery ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,General Surgery ,business ,Colorectal Surgery - Abstract
AIM: There is little evidence to support choice of technique and configuration for stapled anastomoses after right hemicolectomy and ileocaecal resection. This study aimed to determine the relationship between stapling technique and anastomotic failure.METHOD: Any unit performing gastrointestinal surgery was invited to contribute data on consecutive adult patients undergoing right hemicolectomy or ileocolic resection to this prospective, observational, international, multicentre study. Patients undergoing stapled, side-to-side ileocolic anastomoses were identified and multilevel, multivariable logistic regression analyses were performed to explore factors associated with anastomotic leak.RESULTS: One thousand three hundred and forty-seven patients were included from 200 centres in 32 countries. The overall anastomotic leak rate was 8.3%. Upon multivariate analysis there was no difference in leak rate with use of a cutting stapler for apical closure compared with a noncutting stapler (8.4% vs 8.0%, OR 0.91, 95% CI 0.54-1.53, P = 0.72). Oversewing of the apical staple line, whether in the cutting group (7.9% vs 9.7%, OR 0.87, 95% CI 0.52-1.46, P = 0.60) or noncutting group (8.9% vs 5.7%, OR 1.40, 95% CI 0.46-4.23, P = 0.55) also conferred no benefit in terms of reducing leak rates. Surgeons reporting to be general surgeons had a significantly higher leak rate than those reporting to be colorectal surgeons (12.1% vs 7.3%, OR 1.65, 95% CI 1.04-2.64, P = 0.04).CONCLUSION: This study did not identify any difference in anastomotic leak rates according to the type of stapling device used to close the apical aspect. In addition, oversewing of the anastomotic staple lines appears to confer no benefit in terms of reducing leak rates. Although general surgeons operated on patients with more high-risk characteristics than colorectal surgeons, a higher leak rate for general surgeons which remained after risk adjustment needs further exploration.
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- 2018
30. Immune modulation and apoptosis induction: Two sides of the antitumoral activity of imiquimod
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Schön, M. P. and Schön, M.
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- 2004
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31. Correction to: Prognostic Factors in Overall Survival of Patients with Unresectable Intrahepatic Cholangiocarcinoma Treated by Means of Yttrium-90 Radioembolization: Results in Therapy-Naïve Patients
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Reimer, P., Virarkar, M. K., Binnenhei, M., Justinger, C., Schön, M. R., and Tatsch, K.
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- 2018
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32. Nd:YAG- und gepulste Farbstofflaser-Therapie von 271 infantilen Hämangiomen bei 149 Kindern: eine retrospektive Analyse: FV09/02
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Brehmer, F., Lockmann, A., Grönemeyer, L.-L., Haenssle, H. A., Zutt, M., von Fintel, H., Kühnle, I., Schön, M. P., and Thoms, K.-M.
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- 2015
33. Was gibt es Neues in Klinik und Therapie?: PV05/02
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Schön, M. P.
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- 2015
34. Corrigendum to “Improving contrast enhancement in pulmonary CTA: The value of breathing maneuvers” [Eur J Radiol Open 7 (2020) 100280]
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Manava, P., Galster, M., Schoen, M., Ficker, J., Lell, M.M., Adamus, R., and Bruch, M.
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- 2021
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35. Alleviation of chronic venous leg ulcers with a hand-held dielectric barrier discharge plasma generator (PlasmaDerm® VU-2010): results of a monocentric, two-armed, open, prospective, randomized and controlled trial (NCT01415622)
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Brehmer, F., Haenssle, H. A., Daeschlein, G., Ahmed, R., Pfeiffer, S., Görlitz, A., Simon, D., Schön, M. P., Wandke, D., and Emmert, S.
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- 2015
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36. Melanoma thickness: the role of patients’ characteristics, risk indicators and patterns of diagnosis
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Haenssle, H. A., Hoffmann, S., Holzkamp, R., Samhaber, K., Lockmann, A., Fliesser, M., Emmert, S., Schön, M. P., Rosenberger, A., and Buhl, T.
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- 2015
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37. Ist die brusterhaltende Therapie des Mammakarzinoms ohne postoperative Strahlentherapie gerechtfertigt?
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Schön, M., Liebeskind, U., Peek, U., Schlag, P. M., Hartel, W., editor, and Pichlmayr, R.
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- 1996
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38. Surface-wave tomography at mining sites — A case study from Central Sweden
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Papadopoulou*, M., primary, Da Col, F., additional, Socco, L.V., additional, Hu, S., additional, Bäckström, E., additional, Schön, M., additional, Marsden, P., additional, and Malehmir, A., additional
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- 2021
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39. IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
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Prelli Bozzo C, Nchioua R, Volcic M, Koepke L, Krüger J, Schütz D, Heller S, Stürzel CM, Kmiec D, Conzelmann C, Müller J, Zech F, Braun E, Groß R, Wettstein L, Weil T, Weiß J, Diofano F, Rodríguez Alfonso AA, Wiese S, Sauter D, Münch J, Goffinet C, Catanese A, Schön M, Boeckers TM, Stenger S, Sato K, Just S, Kleger A, Sparrer KMJ, Kirchhoff F.
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- 2021
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40. Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects
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Klöting, N., Kovacs, P., Kern, M., Heiker, J. T., Fasshauer, M., Schön, M. R., Stumvoll, M., Beck-Sickinger, A. G., and Blüher, M.
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- 2011
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41. Epidermolysis bullosa simplex: greater penetrance due to a keratin 5 gene variant
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Jantke, M., Has, C., Haenssle, H. A., Schön, M. P., and Emmert, S.
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- 2014
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42. Successful therapy with anakinra in a patient with generalized pustular psoriasis carrying IL36RN mutations
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Hüffmeier, U., Wätzold, M., Mohr, J., Schön, M. P., and Mössner, R.
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- 2014
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43. Patients with Crohn's disease have longer post-operative in-hospital stay than patients with colon cancer but no difference in complications' rate
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Dich Grandt, S, El-Hussuna, A, Frasson, M, Singh, B, Gallo, G, Pata, F, Negoi, I, Pinkney, T, Zmora, O, Bhangu, A, Battersby, N, Chaudhri, S, Nepogodiev, D, Vennix, S, Glasbey, J, Minaya, A, Basso, L, Pukuotukai, M, Kelly, Me, Sánchez Guillén, L, Pellino, G, Buchs, N, Morton, D, Bemelman, W, Christensen, P, D'Hoore, A, Laurberg, S, Rubbini, M, Vaizey, C, Magill, L, Perry, R, Sheward, N, Mortensen, Rn, Cillo, M, Estefania, D, Patron Uriburu, J, Ruiz, H, Salomon, M, Makhmudov, A, Selnyahina, L, Varabei, A, Vizhynis, Y, Claeys, D, Defoort, B, Muysoms, F, Pletinckx, P, Vergucht, V, Debergh, I, Feryn, T, Reusens, H, Francart, D, Jehaes, C, Markiewicz, S, Monami, B, Weerts, J, Bouckaert, W, Houben, B, Knol, J, Sergeant, G, Vangertruyden, G, Haeck, L, Lange, C, Sommeling, C, Vindevoghel, K, Castro, S, De Bruyn, H, Huyghe, M, De Wolf, E, Reynders, D, de Buck van Overstraeten, A, Wolthuis, A, Delibegovic, S, Christiani, A, Marchiori, M Jr, Rocha de Moraes, C, Tercioti, V Jr, Arabadjieva, E, Bulanov, D, Dardanov, D, Stoyanov, V, Yonkov, A, Angelov, K, Maslyankov, S, Sokolov, M, Todorov, G, Toshev, S, Georgiev, Y, Karashmalakov, A, Zafirov, G, Wang, X, Condic, D, Kraljik, D, Mrkovic, H, Pavkovic, V, Raguž, K, Bencurik, V, Holášková, E, Skrovina, M, Farkašová, M, Grolich, T, Kala, Z, Antos, F, Pruchova, V, Sotona, O, Chobola, M, Dusek, T, Ferko, A, Örhalmi, J, Hoch, J, Kocian, P, Martinek, L, Bernstein, I, Gotschalck Sunesen, K, Leunbach, J, Thorlacius-Ussing, O, Uth Oveson, A, Dahl Chirstensen, S, Gamez, V, Oeting, M, Schou Loeve, U, Ugianskis, A, Jessen, M, Krarup, Pm, Linde, K, Mirza, Q, Overgaard Stovring, J, Erritzøe, L, Loft Jakobsen, H, Lykke, J, Palmgren Colov, E, Husted Madsen, A, Linde Friis, T, Amstrup Funder, J, Dich, R, Kjær, S, Rasmussen, S, Schlesinger, N, Dilling Kjaer, M, Qvist, N, Khalid, A, Ali, G, Hadi, S, Rosell Walker, L, Kivelä, A, Lehtonen, T, Lepistö, A, Scheinin, T, Siironen, P, Kössi, J, Kuusanmäki, P, Tomminen, T, Turunen, A, Rautio, T, Vierimaa, M, Huhtinen, H, Karvonen, J, Lavonius, M, Rantala, A, Varpe, P, Cotte, E, Francois, Y, Glehen, O, Kepenekian, V, Passot, G, Maggiori, L, Manceau, G, Panis, Y, Gout, M, Rullier, E, van Geluwe, B, Chafai, N, Lefevre, Jh, Parc, Y, Tiret, E, Couette, C, Duchalais, E, Agha, A, Hornberger, M, Hungbauer, A, Iesalnieks, I, Weindl, I, Crescenti, F, Keller, M, Kolodziejski, N, Scherer, R, Sterzing, D, Bock, B, Boehm, G, El-Magd, M, Krones, C, Niewiera, M, Buhr, J, Cordesmeyer, S, Hoffmann, M, Krückemeier, K, Vogel, T, Schön, M, Baral, J, Lukoschek, T, Münch, S, Pullig, F, Horisberger, K, Kienle, P, Magdeburg, J, Post, S, Batzalexis, K, Germanos, S, Agalianos, C, Dervenis, C, Gouvas, N, Kanavidis, P, Kottikias, A, Katsoulis, Ie, Korkolis, D, Plataniotis, G, Sakorafas, G, Akrida, I, Argentou, M, Kollatos, C, Lampropoulos, C, Tsochatzis, S, Besznyák, I, Bursics, A, Egyed, T, Papp, G, Svastics, I, Atladottir, J, Möller, P, Sigurdsson, H, Stefánsson, T, Valsdottir, E, Andrews, E, Foley, N, Hechtl, D, 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C, Antonio Gracia Solanas, J, Córdoba Díaz de Laspra, E, Arredondo Chaves, J, Diez González, P, Elosua, T, Sahagún, J, Turienzo Frade, A, Álvarez Conde, J, Castrillo, E, Diaz Maag, R, Maderuelo, V, Saldarriaga, L, Aldrey Cao, I, Fernández Varela, X, Núñez Fernández, S, Parajó Calvo, A, Villar Álvarez, S, Blesa Sierra, I, Lozano, R, Márquez, M, Porcel, O, Menendez, P, Fernández Hevia, M, Flores Sigüenza, L, Jimenez Toscano, M, Lacy Fortuny, A, Ordoñez, J, Espi, A, Garcia Botello, S, Martín Arévalo, J, Moro Valdezate, D, Pla, Martív, Blanco Antona, F, Abrisqueta, J, Ibañez Canovas, N, Lujan Mompean, J, Escolá Ripoll, D, Martinez Gonzalez, S, Parodi, J, Fernández López, A, Ramos Fernández, M, Castellvi Valls, J, Ortiz de Zarate, L, Ribas, R, Sabia, D, Viso, L, Alonso Gonçalves, S, José Gil, M, Pascual Damieta, M, Pera, M, Salvans Ruiz, S, Bernal, J, Landete, F, Ais, G, Etreros, J, Aguiló Lucia, J, Boscá, A, Deusa, S, García del Caño, J, Viciano, V, García Armengol, J, Roig, J, Blas, J, Escartin, J, Fatás, J, Fernando, J, Ferrer, R, Arias Pacheco, R, García Flórez, L, Moreno Gijón, M, Otero Díez, J, Solar Garcia, L, Aguilar Teixido, F, Balaguer Ojo, C, Bargallo Berzosa, J, Lamas Moure, S, Enrique Sierra, J, Fermiñán, A, Herrerias, F, Rufas, M, Viñas, J, Codina Cazador, A, Farrés, R, Gómez, N, Julià, D, Planellas, P, López, J, Luna, A, Maristany, C, Muñoz Duyos, A, Puértolas, N, Alcantara Moral, M, Serra Aracil, X, Concheiro Coello, P, Gómez, D, Carton, C, Miguel, A, Reoyo Pascual, F, Valero Cerrato, X, Zambrano Muñoz, R, Cervera Aldama, J, García González, J, Ramos Prada, J, Santamaría Olabarrieta, M, Urigüen Echeverría, A, Coves Alcover, R, Espinosa Soria, J, Fernandez Rodriguez, E, Hernandis Villalba, J, Maturana Ibañez, V, De la Torre Gonzalez, F, Huerga, D, Pérez Viejo, E, Rivera, A, Ruiz Ucar, E, Garcia Septiem, J, Jiménez, V, Jiménez Miramón, J, Ramons Rodriquez, J, Rodriguez Alvarez, V, Garcea, A, Ponchietti, L, Borda, N, Enriquez Navascues, J, Saralegui, Y, Febles Molina, G, Nogues, E, Rodríguez, M, Roque Castellano, C, Sosa Quesada, Y, Alvarez Gallego, M, Pascual, I, Rubio Perez, I, Diaz San Andrés, B, Tone Villanueva, F, Alonso, J, Cagigas, C, Castillo, J, Gómez, M, Martín Parra, J, Mengual Ballester, M, Pellicer Franco, E, Soria Aledo, V, Valero Navarro, G, Caballero Rodríguez, E, Gonzalez De Chaves, P, Hernandez, G, Perez Alvarez, A, Soto Sanchez, A, Cesar Becerra Garcia, F, Guillermo Alonso Roque, J, López, Rodríguez, Arias, F, Del Valle Ruiz, Sr, Sánchez De La Villa, G, Compañ, A, García Marín, A, Nofuentes, C, Orts, Micóf, Pérez Auladell, V, Carrasco, M, Duque Perez, C, Gálvez Pastor, S, Navarro Garcia, I, Sanchez Perez, A, Enjuto, D, Manuel Bujalance, F, Marcelin, N, Pérez, M, Serrano García, R, Cabrera, A, de la Portilla, F, Diaz Pavon, J, Jimenez Rodriguez, R, Vazquez Monchul, J, Martínez Alegre, J, Ortega, I, Picardo Nieto Antonio, A, Caro, A, Escuder, J, Feliu, F, Millan, M, Alos Company, R, Frangi Caregnato, A, Lozoya Trujillo, R, Rodríguez Carrillo, R, Ruiz Carmona, M, Alonso, N, Ambrona Zafra, D, Amilka Ayala, B, Bonnin Pascual, Cj, Pineño Flores, C, Alcazar Montero, J, Angoso Clavijo, M, Garcia, J, Sanchez Tocino, J, Gómez Alcazar, C, Costa Navarro, D, Ferri Romero, J, Rey Riveiro, M, Romero Simó, M, Arencibia, B, Esclapez, P, García Granero, E, Granero, P, Medina Fernández, Fj, Gallardo Herrera, Ab, Diaz López, C, Navarro Rodriguez, E, Torres Tordera, E, Arenal, J, Citores, M, Marcos, J, Sánchez, J, Tinoco, C, Espin, E, Garcia Granero, A, Jimenez Gomez, L, Sanchez Garcia, J, Vallribera, F, Folkesson, J, Sköldberg, F, Bergman, K, Borgström, E, Frey, J, Silfverberg, A, Söderholm, M, Nygren, J, Segelman, J, Gustafsson, D, Lagerqvist, A, Papp, A, Pelczar, M, Abraham Nordling, M, Ahlberg, M, Sjovall, A, Tengstrom, J, Hagman, K, Chabok, A, Ezra, E, Nikberg, M, Smedh, K, Tiselius, C, Al Naimi, N, Dao Duc, M, Meyer, J, Mormont, M, Ris, F, Prevost, G, Villiger, P, Hoffmann, H, Kettelhack, C, Kirchhoff, P, Oertli, D, Weixler, B, Aytac, B, Leventoglu, S, Mentes, B, Yuksel, O, Demirbas, S, Busra Ozkan, B, Selçuk Özbalci, G, Sungurtekin, U, Gülcü, B, Ozturk, E, Yilmazlar, T, Challand, C, Fearnhead, N, Hubbard, R, Kumar, S, Arthur, J, Barben, C, Skaife, P, Slawik, S, Williams, M, Zammit, M, Barker, J, French, J, Sarantitis, I, Slawinski, C, Clifford, R, Eardley, N, Johnson, M, Mcfaul, C, Vimalachandran, D, Allan, S, Bell, A, Oates, E, Shanmugam, V, Brigic, A, Halls, M, Pucher, P, Stubbs, B, Agarwal, T, Chopada, A, Mallappa, S, Pathmarajah, M, Sugden, C, Brown, C, Macdonald, E, Mckay, A, Richards, J, Robertson, A, Kaushal, M, Patel, P, Tezas, S, Touqan, N, Ayaani, S, Marimuthu, K, Piramanayagam, B, Vourvachis, M, Iqbal, N, Korsgen, S, Seretis, C, Shariff, U, Arnold, S, Chan, H, Clark, E, Fernandes, R, Moran, B, Bajwa, A, Mcarthur, D, Cao, K, Cunha, P, Pardoe, H, Quddus, A, Theodoropoulou, K, Bolln, C, Denys, G, Gillespie, M, Manimaran, N, Reidy, J, Malik, Ai, Malik, A, Pitt, J, Aryal, K, 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Crohn’s disease ,medicine.medical_specialty ,Complications ,Colorectal cancer ,SURGERY ,medicine.medical_treatment ,Bowel resection ,Disease ,Inflammatory bowel disease ,NO ,COLORECTAL-CANCER ,03 medical and health sciences ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,MORBIDITY ,0302 clinical medicine ,Medicine ,Crohn’s disease, Colon cancer, Complications, Length of stay, Bowel resection, Right hemicolectomy ,DIVERTICULAR-DISEASE ,Colon cancer ,Length of stay ,Right hemicolectomy ,colon cancer ,complications ,length of stay ,bowel resection ,right hemicolectomy ,PREOPERATIVE OPTIMIZATION ,RISK ,Crohn's disease ,ddc:617 ,business.industry ,medicine.disease ,3126 Surgery, anesthesiology, intensive care, radiology ,digestive system diseases ,Surgery ,030220 oncology & carcinogenesis ,3121 General medicine, internal medicine and other clinical medicine ,Diverticular disease ,Prospective Study ,030211 gastroenterology & hepatology ,SMOKING ,business ,Complication ,Hospital stay ,INFLAMMATORY-BOWEL-DISEASE - Abstract
BACKGROUND: Right hemicolectomy or ileocecal resection are used to treat benign conditions like Crohn's disease (CD) and malignant ones like colon cancer (CC).AIM: To investigate differences in pre- and peri-operative factors and their impact on post-operative outcome in patients with CC and CD.METHODS: This is a sub-group analysis of the European Society of Coloproctology's prospective, multi-centre snapshot audit. Adult patients with CC and CD undergoing right hemicolectomy or ileocecal resection were included. Primary outcome measure was 30-d post-operative complications. Secondary outcome measures were post-operative length of stay (LOS) at and readmission.RESULTS: Three hundred and seventy-five patients with CD and 2,515 patients with CC were included. Patients with CD were younger (median = 37 years for CD and 71 years for CC (P < 0.01), had lower American Society of Anesthesiology score (ASA) grade (P < 0.01) and less comorbidity (P < 0.01), but were more likely to be current smokers (P < 0.01). Patients with CD were more frequently operated on by colorectal surgeons (P < 0.01) and frequently underwent ileocecal resection (P < 0.01) with higher rate of de-functioning/primary stoma construction (P < 0.01). Thirty-day post-operative mortality occurred exclusively in the CC group (66/2515, 2.3%). In multivariate analyses, the risk of post-operative complications was similar in the two groups (OR 0.80, 95%CI: 0.54-1.17; P = 0.25). Patients with CD had a significantly longer LOS (Geometric mean 0.87, 95%CI: 0.79-0.95; P < 0.01). There was no difference in re-admission rates. The audit did not collect data on post-operative enhanced recovery protocols that are implemented in the different participating centers.CONCLUSION: Patients with CD were younger, with lower ASA grade, less comorbidity, operated on by experienced surgeons and underwent less radical resection but had a longer LOS than patients with CC although complications' rate was not different between the two groups.
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- 2019
44. Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis
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Geserick, P, Drewniok, C, Hupe, M, Haas, T L, Diessenbacher, P, Sprick, M R, Schön, M P, Henkler, F, Gollnick, H, Walczak, H, and Leverkus, M
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- 2008
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45. Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans
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Klöting, N., Schleinitz, D., Ruschke, K., Berndt, J., Fasshauer, M., Tönjes, A., Schön, M. R., Kovacs, P., Stumvoll, M., and Blüher, M.
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- 2008
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46. Imiquimod: mode of action
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Schön, M. P. and Schön, M.
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- 2007
47. Verbesserung und Beschleunigung der Regeneration des traumatisierten peripheren Skelettmuskels durch Erythropoetin
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Rotter, Robert, Menshykova, M., Winkler, T., Matziolis, G., Stratos, I., Schoen, M., Bittorf, T., Mittlmeier, T., Vollmar, B., Steinau, H. -U., editor, Schackert, H. K., editor, and Bauer, H., editor
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- 2007
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48. Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes
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Berndt, J., Kovacs, P., Ruschke, K., Klöting, N., Fasshauer, M., Schön, M. R., Körner, A., Stumvoll, M., and Blüher, M.
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- 2007
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49. Predictors for Anastomotic Leak, Postoperative Complications, and Mortality After Right Colectomy for Cancer: Results From an International Snapshot Audit
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Gallo, G., Pata, F., Vennix, S., Laurberg, S., Morton, D., Rubbini, M., Vaizey, C., Magill, L., Perry, R., Sheward, N., Hervas, D., Cillo, M., Estefania, D., Uriburu, J.P., Ruiz, H., Solomon, M., Makhmudov, A., Selnyahina, L., Varabei, A., Vizhynis, Y., Claeys, D., Defoort, B., Muysoms, F., Pletinckx, P., Vergucht, V., Debergh, I., Feryn, T., Reusens, H., Nachtergaele, M., Francart, D., Jehaes, C., Markiewicz, S., Monami, B., Weerts, J., Houben, B., Haeck, L., Lange, C., Sommeling, C., Vindevoghel, K., Castro, S., De Bruyn, H., Huyghe, M., De Wolf, E., Reynders, D., D'Hoore, A., De Buck Van Overstraeten, A., Wolthuis, A., Delibegovic, S., Christiani, A., Marchiori, M., Jr., De Moraes, C.R., Tercioti, V., Jr., Arabadjieva, E., Bulanov, D., Dardanov, D., Stoyanov, V., Yonkov, A., Angelov, K., Maslyankov, S., Sokolov, M., Todorov, G., Toshev, S., Georgiev, Y., Karashmalakov, A., Zafirov, G., Wang, X., Condic, D., Kraljik, D., Mrkovic, H., Pavkovic, V., Raguž, K., Bencurik, V., Holášková, E., Skrovina, M., Farkašová, M., Grolich, T., Kala, Z., Antos, F., Pruchova, V., Sotona, O., Chobola, M., Dusek, T., Ferko, A., Örhalmi, J., Hoch, J., Kocian, P., Martinek, L., Bernstein, I., Sunesen, K.G., Leunbach, J., Thorlacius-Ussing, O., Oveson, A.U., Christensen, P., Chirstensen, S.D., Gamez, V., Oeting, M., Loeve, U.S., Ugianskis, A., Jessen, M., Krarup, P., Linde, K., Mirza, Q., Stovring, J.O., Erritzøe, L., Jakobsen, H.L., Lykke, J., Colov, E.P., Madsen, A.H., Friis, T.L., Funder, J.A., Dich, R., Kjar, S., Rasmussen, S., Schlesinger, N., Kjaer, M.D., Qvist, N., Khalid, A., Ali, G., El-Hussuna, A., Hadi, S., Walker, L.R., Kivelä, A., Lehtonen, T., Lepistö, A., Scheinin, T., Siironen, P., Kössi, J., Kuusanmäki, P., Tomminen, T., Turunen, A., Rautio, T., Vierimaa, M., Huhtinen, H., Karvonen, J., Lavonius, M., Rantala, A., Varpe, P., Cotte, E., Francois, Y., Glehen, O., Kepenekian, V., Passot, G., Maggiori, L., Manceau, G., Panis, Y., Gout, M., Rullier, E., Van Geluwe, B., Chafai, N., Lefevre, J., Parc, Y., Tire, E., Couette, C., Duchalais, E., Agha, A., Hornberger, M., Hungbauer, A., Iesalnieks, I., Weindl, I., Crescenti, F., Keller, M., Kolodziejski, N., Scherer, R., Sterzing, D., Bock, B., Boehm, G., El-Magd, M., Krones, C., Niewiera, M., Buhr, J., Cordesmeyer, S., Hoffmann, M., Krückemeier, K., Vogel, T., Schön, M., Baral, J., Lukoschek, T., Münch, S., Pullig, F., Horisberger, K., Kienle, P., Magdeburg, J., Post, S., Batzalexis, K., Germanos, S., Agalianos, C., Dervenis, C., Gouvas, N., Kanavidis, P., Kottikias, A., Katsoulis, I., Korkolis, D., Plataniotis, G., Sakorafas, G., Akrida, I., Argentou, M., Kollatos, C., Lampropoulos, C., Tsochatzis, S., Besznyák, I., Bursics, A., Egyed, T., Papp, G., Svastics, I., Atladottir, J., Möller, P., Sigurdsson, H., Stefánsson, T., Valsdottir, E., Andrews, E., Foley, N., Hechtl, D., Majeed, M., McCourt, M., Hanly, A., Hyland, J., Martin, S., O'Connell, R., Winter, D., Connelly, T., Joyce, W., Wrafter, P., Berkovitz, R., Avital, S., Yahia, I.H., Herman, N., Shpitz, B., White, I., Lishtzinsky, Y., Tsherniak, A., Wasserberg, N., Horesh, N., Keler, U., Pery, R., Shapiro, R., Zmora, O., Tulchinsky, H., Badran, B., Dayan, K., Iskhakov, A., Lecaros, J., Nabih, N., Angrima, I., Bardini, R., Pizzolato, E., Tonello, M., Arces, F., Balestri, R., Ceccarelli, C., Prosperi, V., Rossi, E., Giannini, I., Vincenti, L., Di Candido, F., Di Iena, M., Guglielmi, A., Iambrenghi, O., Marsanic, P., Mellano, A., Muratore, A., Annecchiarico, M., Bencini, L., Bonapasta, S., Coratti, A., Guerra, F., Asteria, C., Boccia, L., Gerard, L., Pascariello, A., Manca, G., Marino, F., Casaril, A., Inama, M., Moretto, G., Bacchelli, C., Carvello, M., Mariani, N., Montorsi, M., Spinelli, A., Romairone, E., Scabini, S., Belli, A., Bianco, F., De Franciscis, S., Romano, G.M., Delrio, P., Pace, U., Rega, D., Sassaroli, C., Scala, D., De Luca, R., Ruggieri, E., Elbetti, C., Garzi, A., Romoli, L., Scatizzi, M., Vannucchi, A., Curletti, G., Durante, V., Galleano, R., Mariani, F., Reggiani, L., Bellomo, R., Infantino, A., Franceschilli, L., Sileri, P., Clementi, I., Coletta, D., La Torre, F., Mingoli, A., Velluti, F., Di Giacomo, A., Fiorot, A., Massani, M., Padoan, L., Ruffolo, C., Caruso, S., Franceschini, F., Laessig, R., Monaci, I., Rontini, M., De Nardi, P., Lemma, M., Rosati, R., Tamburini, A., De Luca, M., Sartori, A., Benevento, A., Bottini, C., Ferrari, C., Tessera, G., Pellino, G., Selvaggi, F., Lanzani, A., Romano, F., Sgroi, G., Steccanella, F., Turati, L., Yamamoto, T., Ancans, G., Gerkis, S., Leja, M., Pcolkins, A., Sivins, A., Latkauskas, T., Lizdenis, P., Saladžinskas, Ž., Švagždys, S., Tamelis, A., Razbadauskas, A., Sokolovas, M., Dulskas, A., Samalavicius, N., Jotautas, V., Mikalauskas, S., Poskus, E., Poskus, T., Strupas, K., Camenzuli, C., Cini, C., Predrag, A., Psaila, J., Spiteri, N., Bemelman, W., Buskens, C., De Groof, J., Gooszen, J., Tanis, P., Belgers, E., Davids, P., Furnee, E., Postma, E., Pronk, A., Smakman, N., Clermonts, S., Zimmerman, D., Omloo, J., Van Der Zaag, E., Van Duijvendijk, P., Wassenaar, E., Bruijninckx, M., De Graff, E., Doornebosch, P., Tetteroo, G., Vermaas, M., Iordens, G., Knops, S., Toorenvliet, B., Van Westereenen, E., Boerma, E., Coene, P., Van Der Harst, E., Van Der Pool, A., Raber, M., Melenhorst, J., De Castro, S., Gerhards, M., Arron, M., Bremers, A., De Wilt, H., Ferenschild, F., Yauw, S., Cense, H., Demirkiran, A., Hunfeld, M., Mulder, I., Nonner, J., Swank, H., Van Wagensveld, B., Bolmers, M., Briel, J., Van Geloven, N., Van Rossem, C., Klemann, V., Konsten, J., Leenders, B., Schok, T., Bleeker, W., Gidwani, A., Lawther, R., Loughlin, P., Skelly, B., Spence, R., Brun, M., Helgeland, M., Ignjatovic, D., Øresland, T., Peyman, Y., Backe, I.F., Sjo, O.H., Nesbakken, A., Tandberg-Eriksen, M., Cais, A., Traland, J.H., Herikstad, R., Kørner, H., Lauvland, N., Jajtner, D., Kabiesz, W., Rak, M., Gmerek, L., Horbacka, K., Horst, N., Krokowicz, P., Kwiatkowski, A., Pasnik, K., Karcz, P., Romaniszyn, M., Rusek, T., Walega, P., Czarencki, R., Obuszko, Z., Sitarska, M., Wojciech, W., Zawadzki, M., Amado, S., Clara, P., Couceiro, A., Malaquias, R., Rama, N., Almeida, A., Barbosa, E., Cernadas, E., Duarte, A., Silva, P., Costa, S., Insua, C.M., Pereira, J., Pereira, C., Sacchetti, M., Ferreira, R.A.M., Pinto, B.C., Sousa, P.J.V., Oliveira, A., Cardoso, R., Carlos, S., Corte-Real, J., Pereira, P.M., Souto, R., Carneiro, C., Marinho, R., Nunes, V., Rocha, R., Sousa, M., Leite, J., Melo, F., Pimentel, J., Ventura, L., Nova, C.V., Copǎescu, C., Bintintan, V., Ciuce, C., Dindelegan, G., Scurtu, R., Seicean, R., Domansky, N., Karachun, A., Moiseenko, A., Pelipas, Y., Petrov, A., Pravosudov, I., Aiupov, R., Akmalov, Y., Parfenov, A., Suleymanov, N., Tarasov, N., Jumabaev, H., Mamedli, Z., Rasulov, A., Aliev, I., Chernikovskiy, I., Kochnev, V., Komyak, K., Smirnov, A., Achkasov, S., Bolikhov, K., Shelygin, Y., Sushkov, O., Zapolskiy, A., Gvozdenovic, M., Jovanovic, D., Lausevic, Z., Cvetković, D., Maravić, M., Milovanovic, B., Stojakovic, N., Tripković, I., Mihajlovic, D., Nestorovic, M., Pecic, V., Petrovic, D., Stanojevic, G., Barisic, G., Dimitrijevic, I., Krivokapic, Z., Markovic, V., Popovic, M., Aleksic, A., Dabic, D., Kostic, I., Milojkovic, A., Perunicic, V., Dragana, R., Lukic, D., Petrovic, T., Radovanovic, Z., Cuk, V., Kenic, M., Kovacevic, B., Krdzic, I., Korcek, J., Rems, M., Toplak, J., Escarrâ, J., Barrionuevo, M.G., Golda, T., Moreno, E.K., Martin, C.Z., Laso, C.A., Cumplido, P., Padin, H., Fons, J.B., Hernández-Lizoain, J., Martinez-Ortega, P., Molina-Fernández, M., Sánchez-Justicia, C., Solanas, J.A.G., De Laspra, E.C.D., Elia-Guedea, M., Gallego, E., Ramirez, J., Chaves, J.A., González, P.D., Elosua, T., Sahagún, J., Frade, A.T., Conde, J.A., Castrillo, E., Maag, R.D., Maderuelo, V., Saldarriaga, L., Cao, I.A., Varela, X.F., Fernández, S.N., Calvo, A.P., Álvarez, S.V., Sierra, I.B., Lozano, R., Márquez, M., Porcel, O., Menendez, P., Hevia, M.F., Sigüenzo, L.F., Toscano, M.J., Fortuny, A.L., Trujillo, J.O., Espi, A., Garcia-Botello, S., Martín-Arévalo, J., Moro-Valdezate, D., Pla-Martí, V., Blanco-Antona, F., Abrisqueta, J., Canovas, N.I., Mompean, J.L., Ripoll, D.E., Gonzalez, S.M., Parodi, J., López, A.F., Fernández, M.R., Valls, J.C., De Zarate, L.O., Ribas, R., Sabia, D., Viso, L., Gonçalves, S.A., Egea, M.J.G., Damieta, M.P., Pera, M., Ruiz, S.S., Bernal, J., Landete, F., Ais, G., Alonso, E., Lucia, J.A., Boscá, A., Deusa, S., Del Caño, J.G., Viciano, V., García-Armengol, J., Roig, J., Blas, J., Escartin, J., Fatás, J., Fernando, J., Ferrer, R., Pacheco, R.A., Flórez, L.G., Gijón, M.M., Díez, J.O., Garcia, L.S., Teixido, F.A., Ojo, C.B., Berzosa, J.B., Moure, S.L., Sierra, J.E., Fermiñán, A., Herrerias, F., Rufas, M., Viñas, J., Codina-Cazador, A., Farrés, R., Gómez, N., Julià, D., Planellas, P., López, J., Luna, A., Maristany, C., Duyos, A.M., Puértolas, N., Moral, M.A., Serra-Aracil, X., Coello, P.C., Gómez, D., Carton, C., Miguel, A., Pascual, F.R., Cerrato, X.V., Muñoz, R.Z., Cervera-Aldama, J., González, J.G., Ramos-Prada, J., Santamaría-Olabarrieta, M., Urigüen-Echeverría, A., Alcover, R.C., Soria, J.E., Rodriguez, E.F., Hernandis, J., Ibañez, V.M., De La Torre Gonzalez, F., Huerga, D., Viejo, E.P., Rivera, A., Ucar, E.R., Garcia-Septiem, J., Jiménez, V., Miramón, J.J., Rodriquez, J.R., Alvarez, V.R., Garcea, A., Ponchietti, L., Borda, N., Enriquez-Navascues, J., Saralegui, Y., Molina, G.F., Nogues, E., Méndez, A.R., Castellano, C.R., Quesada, Y.S., Gallego, M., Pascual, I., Perez, I., San Andrés, B., Villanueva, F., Alonso, J., Cagigas, C., Castillo, J., Gómez, M., Martín-Parra, J., Ballester, M.M., Franco, E.P., Aledo, V.S., Navarro, G.V., Rodriquez, E.C., De Chaves, P.G., Hernandez, G., Alvarez, A.P., Sanchez, A.S., Garcia, F.C.B., Roque, J.G.A., Aria, F.L.R., Del Valle Ruiz, S.R., De La Villa, G.S., Compañ, A., Marín, A.G., Nofuentes, C., Micó, F.O., Auladell, V.P., Carrasco, M., Perez, C.D., Gálvez-Pastor, S., Garcia, I.N., Perez, A.S., Enjuto, D., Bujalance, F.M., Marcelin, N., Pérez, M., García, R.S., Cabrera, A., De La Portilla, F., Diaz-Pavon, J., Jimenez-Rodriguez, R., Vazquez-Monchul, J., González, J.D., Pérez, R.G., Castellano, J.R., De La Rua, J.R., Toral, B.C., Alustiza, J.E., Fernández, L., Ramirez, J.R., Ramos, J.S., Alias, D., Garcia-Olmo, D., Guadalajara, H., Herreros, M., Pacheco, P., Del Castillo Díez, F., Pinto, F.L., Alegre, J.M., Ortega, I., Antonio, A.P.N., Caro, A., Escuder, J., Feliu, F., Millan, M., Company, R.A., Caregnato, A.F., Trujillo, R.L., Carrillo, R.R., Carmona, M.R., Alonso, N., Zafra, D.A., Candia, B.A.A., Pascual, J.B., Flores, C.P., Montero, J.A., Clavijo, M.A., Garcia, J., Tocino, J.S., Alcazar, C., Navarro, D.C., Romero, J.F., Riveiro, M.R., Romero, M., Arencibia, B., Esclapez, P., Frasson, M., García-Granero, E., Granero, P., Herrera, A.B.G., Diaz, L., Tordera, E.M.T., Fernandez, F.M., Rodriguez, E.N., Arenal, J., Citores, M., Marcos, J., Sánchez, J., Tinoco, C., Espin, E., Granero, A.G., Gomez, L.J., Garcia, J.S., Vallribera, F., Folkesson, J., Sköldberg, F., Bergman, K., Borgström, E., Frey, J., Silfverberg, A., Söderholm, M., Nygren, J., Segelman, J., Gustafsson, D., Lagerqvist, A., Papp, A., Pelczar, M., Abraham-Nordling, M., Ahlberg, M., Sjovall, A., Tengstrom, J., Hagman, K., Chabok, A., Ezra, E., Nikberg, M., Smedh, K., Tiselius, C., Al-Naimi, N., Dao Duc, M., Meyer, J., Mormont, M., Ris, F., Prevost, G., Villiger, P., Hoffmann, H., Kettelhack, C., Kirchhoff, P., Oertli, D., Weixler, B., Aytac, B., Leventoglu, S., Mentes, B., Yuksel, O., Demirbas, S., Ozkan, B.B., Özbalci, G.S., Sungurtekin, Uğur, Gülcü, B., Ozturk, E., Yilmazlar, T., Challand, C., Fearnhead, N., Hubbard, R., Kumar, S., Arthur, J., Barben, C., Skaife, P., Slawik, S., Williams, M., Zammit, M., Barker, J., French, J., Sarantitis, I., Slawinski, C., Clifford, R., Eardley, N., Johnson, M., McFaul, C., Vimalachandran, D., Allan, S., Bell, A., Oates, E., Shanmugam, V., Brigic, A., Halls, M., Pucher, P., Stubbs, B., Agarwal, T., Chopada, A., Mallappa, S., Pathmarajah, M., Sugden, C., Brown, C., Macdonald, E., Mckay, A., Richards, J., Robertson, A., Kaushal, M., Patel, P., Tezas, S., Touqan, N., Ayaani, S., Marimuthu, K., Piramanayagam, B., Vourvachis, M., Iqbal, N., Korsgen, S., Seretis, C., Shariff, U., Arnold, S., Battersby, N.J., Chan, H., Clark, E., Fernandes, R., Moran, S., Bajwa, A., McArthur, D., Cao, K., Cunha, P., Pardoe, H., Quddus, A., Theodoropoulou, K., Bolln, C., Denys, G., Gillespie, M., Manimaran, N., Reidy, J., Malik, A., Pitt, J., Aryal, K., El-Hadi, A., Lal, R., Pal, A., Velchuru, V., Chaudhri, S., Cunha, M.O., Singh, B., Thomas, M., Bains, S., Boyle, K., Miller, A., Norwood, M., Yeung, J., Goian, L., Gurjar, S., Saghir, W., Sengupta, N., Stewart-Parker, E., Bailey, S., Khalil, T., Lawes, D., Nikolaou, S., Omar, G., Church, R., Muthiah, B., Garrett, W., Marsh, P., Obeid, N., Chandler, S., Coyne, P., Evans, M., Hunt, L., Lim, J., Oliphant, Z., Papworth, E., Weaver, H., Leon, K.C., Williams, G., Hernon, J., Kapur, S., Moosvi, R., Shaikh, I., Swafe, L., Aslam, M., Evans, J., Ihedioha, U., Kang, P., Merchant, J., Hompes, R., Middleton, R., Broomfield, A., Crutten-Wood, D., Foster, J., Nash, G., Akhtar, M., Boshnaq, M., Eldesouky, S., Mangam, S., Rabie, M., Ahmed, J., Khan, J., Goh, N.M., Shamali, A., Stefan, S., Nepogodiev, D., Pinkney, T.D., Thompson, C., Amin, A., Docherty, J., Lim, M., Walker, K., Watson, A., Hossack, M., Mackenzie, N., Paraoan, M., Alam, N., Daniels, I., Narang, S., Pathak, S., Smart, N., Al-Qaddo, A., Codd, R., Rutka, O., Bronder, C., Crighton, I., Davies, E., Raymond, T., Bookless, L., Griffiths, B., Plusa, S., Carlson, G., Harrison, R., Lees, N., Mason, C., Quayle, J., Branagan, G., Broadhurst, J., Chave, H., Sleight, S., Awad, F., Bhangu, A., Cruickshank, N., Joy, H., Boereboom, C., Daliya, P., Dhillon, A., Watson, N., Watson, R., Artioukh, D., Gokul, K., Javed, M., Kong, R., Sutton, J., Faiz, O., Jenkins, I., Leo, C., Samaranayake, F., Warusavitarne, J., Arya, S., Bhan, C., Mukhtar, H., Oshowo, A., Wilson, J., Duff, S., Fatayer, T., Mbuvi, J., Sharma, A., Cornish, J., Davies, L., Harries, R., Morris, C., Torkington, J., Knight, J., Lai, C., Shihab, O., Tzivanakis, A., Hussain, A., Luke, D., Padwick, R., Torrance, A., Tsiamis, A., Dawson, P., Balfour, A., Brady, R., Mander, J., Paterson, H., Chandratreya, N., Chu, H., Cutting, J., Vernon, S., Ho, C.W., Andreani, S., Patel, H., Warner, M., Tan, J.Y.Q., Iqbal, A., Khan, A., Perrin, K., Raza, A., Tan, S., European Society of Coloproctology Collaborating Group Collaborators, Group, ESCP Cohort Studies Sub-Committee, ESCP Research Committee, Logistical Support and Data Collection, Analysis, Investigators, Radiology and nuclear medicine, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Surgery, MUMC+: MA Heelkunde (9), Graduate School, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA - Cancer Treatment and Quality of Life, Neurology, and Center for Evidence Based Education
- Subjects
Male ,Leak ,Conference Paper ,adverse event ,ileostomy ,non-smoker ,0302 clinical medicine ,middle aged ,antibiotic therapy ,80 and over ,antibiotic agent ,postoperative complication ,emergency surgery ,Colectomy ,cecum ,Aged, 80 and over ,OUTCOMES ,adult ,COLON-CANCER ,Gastroenterology ,operation duration ,clinical trial ,General Medicine ,cohort analysis ,laparoscopic surgery ,ureter injury ,Survival Rate ,aged ,risk factor ,030220 oncology & carcinogenesis ,Cohort ,kidney injury ,030211 gastroenterology & hepatology ,Colonic Neoplasms/mortality ,anastomosis leakage ,liver injury ,prospective study ,medicine.medical_specialty ,SURGICAL STRESS ,ELECTIVE RIGHT ,surgical infection ,03 medical and health sciences ,Humans ,human ,Aged ,clinical audit ,sex ratio ,major clinical study ,mortality ,hemicolectomy ,multicenter study ,RISK-FACTORS ,observational study ,Complication ,Anastomotic leak ,Colon cancer ,Postoperative outcome ,Right colectomy ,general surgery ,surgical mortality ,SURGERY ,very elderly ,morbidity ,Anastomotic Leak ,mortality rate ,open surgery ,Cohort Studies ,Postoperative Complications ,gallbladder disease ,LAPAROSCOPY ,Risk Factors ,Neoplasms ,cancer mortality ,Laparoscopy ,Prospective cohort study ,colon resection ,Medical Audit ,medicine.diagnostic_test ,Mortality rate ,colon tumor ,Middle Aged ,female ,colon cancer ,Right Colectomy ,Colonic Neoplasms ,ileum ,surgical stapling ,Female ,cancer surgery ,Colectomy/adverse effects ,duodenum injury ,small intestine resection ,RESECTION ,reoperation ,Anastomosis ,NO ,MORBIDITY ,medicine ,operative blood loss ,LS7_4 ,percutaneous drainage ,business.industry ,suture technique ,Surgery ,blood vessel injury ,peroperative complication ,elective surgery ,Anastomotic Leak/epidemiology ,pathology ,business - Abstract
A right hemicolectomy is among the most commonly performed operations for colon cancer, but modern high-quality, multination data addressing the morbidity and mortality rates are lacking.This study reports the morbidity and mortality rates for right-sided colon cancer and identifies predictors for unfavorable short-term outcome after right hemicolectomy.This was a snapshot observational prospective study.The study was conducted as a multicenter international study.The 2015 European Society of Coloproctology snapshot study was a prospective multicenter international series that included all patients undergoing elective or emergency right hemicolectomy or ileocecal resection over a 2-month period in early 2015. This is a subanalysis of the colon cancer cohort of patients.Predictors for anastomotic leak and 30-day postoperative morbidity and mortality were assessed using multivariable mixed-effect logistic regression models after variables selection with the Lasso method.Of the 2515 included patients, an anastomosis was performed in 97.2% (n = 2444), handsewn in 38.5% (n = 940) and stapled in 61.5% (n = 1504) cases. The overall anastomotic leak rate was 7.4% (180/2444), 30-day morbidity was 38.0% (n = 956), and mortality was 2.6% (n = 66). Patients with anastomotic leak had a significantly increased mortality rate (10.6% vs 1.6% no-leak patients; p0.001). At multivariable analysis the following variables were associated with anastomotic leak: longer duration of surgery (OR = 1.007 per min; p = 0.0037), open approach (OR = 1.9; p = 0.0037), and stapled anastomosis (OR = 1.5; p = 0.041).This is an observational study, and therefore selection bias could be present. For this reason, a multivariable logistic regression model was performed, trying to correct possible confounding factors.Anastomotic leak after oncologic right hemicolectomy is a frequent complication, and it is associated with increased mortality. The key contributing surgical factors for anastomotic leak were anastomotic technique, surgical approach, and duration of surgery. See Video Abstract at http://links.lww.com/DCR/B165. PREDICTORES DE FUGA ANASTOMóTICA, COMPLICACIONES POSTOPERATORIAS Y MORTALIDAD DESPUéS DE LA COLECTOMíA DERECHA POR CáNCER: RESULTADOS DE UNA AUDITORíA INTERNACIONAL DE CORTO PLAZO: La hemicolectomía derecha se encuentra entre las operaciones más frecuentemente realizadas para cáncer de colon, pero faltan datos modernos multinacionales de alta calidad, que aborden las tasas de morbilidad y mortalidad.Reportar la tasa de morbilidad y mortalidad para cáncer de colon del lado derecho, e identificar predictores de resultados desfavorables a corto plazo, después de la hemicolectomía derecha.Estudio prospectivo observacional de corto plazo.Estudio multicéntrico internacional.El estudio de corto plazo de la Sociedad Europea de Coloproctología de 2015, fue una serie prospectiva multicéntrica internacional, que incluyó a todos los pacientes sometidos a hemicolectomía derecha electiva, de emergencia o resección ileocecal, por un período de dos meses y a principios de 2015. Este es un subanálisis, cohorte de pacientes con cáncer de colon.Los predictores de fuga anastomótica, morbilidad y mortalidad postoperatorias a los 30 días, se evaluaron usando modelos de regresión logística de efectos multivariables mixtos, después de la selección de variables con el método Lasso.De los 2,515 pacientes incluidos, se realizó una anastomosis en el 97,2% (n = 2,444); sutura manual en 38.5% (n = 940) y por engrapadora en 61.5% (n = 1504) casos. La tasa global de fuga anastomótica fue del 7,4% (180/2,444), morbilidad a los 30 días fue del 38,0% (n = 956) y la mortalidad fue del 2,6% (n = 66). Los pacientes con fuga anastomótica tuvieron una tasa de mortalidad significativamente mayor (10,6% frente al 1,6% de pacientes sin fuga, p0,001). En el análisis multivariable, las siguientes variables se asociaron con la fuga anastomótica: mayor duración de la cirugía (OR 1.007 por minuto, p = 0.0037), abordaje abierto (OR 1.9, p = 0.0037) y anastomosis por engrapadora (OR 1.5, p = 0.041).Este es un estudio observacional y por lo tanto podría estar presente el sesgo de selección. Por esta razón, se realizó un modelo de regresión logística multivariable, tratando de corregir posibles factores de confusión.La fuga anastomótica después de la hemicolectomía derecha oncológica, es una complicación frecuente y asociada a mayor mortalidad. Los factores quirúrgicos clave que contribuyeron a la fuga anastomótica, fueron la técnica anastomótica, abordaje quirúrgico y duración de la cirugía. Consulte Video Resumen en http://links.lww.com/DCR/B165. (Traducción-Dr. Fidel Ruiz Healy).
- Published
- 2020
50. Gene Expression Analysis of Papillomas from Proteinase-Activated Receptor-2-Deficient and Wild-Type Mice
- Author
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Rattenholl, A, Seeliger, S, Buddenkotte, J, Ehrchen, J, Schön, M P, Schön, M, Ständer, S, and Steinhoff, M
- Published
- 2006
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