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15 results on '"Scarabin, J.M."'

1. Mutations within the MGC4607 gene cause cerebral cavernous malformations

Author

Denier, C., Goutagny, S., Labauge, P., Krivosic, V., Arnoult, M, Cousin, A., Benabid, A.L., Comoy, J., Frerebeau, P., Gilbert, B., Houtteville, J.P., Jan, M., Lapierre, F., Loiseau, H., Menei, P., Mercier, P., Moreau, J.J., Nivelon-Chevallier, A., Parker, F., Redondo, A.M., Scarabin, J.M., Tremoulet, M., Zerah, M., Maciazek, J., and Tournier-Lasserve, E.

Subjects
Biological sciences
Published
2004

8. Fear as the main feature of epileptic seizures

Author

Biraben, A., Taussig, D., Thomas, P., Even, C., Vignal, J.P., Scarabin, J.M., and Chauvel, P.

Abstract

OBJECTIVES: There are circumstances in which partial seizures may be misdiagnosed as acute psychiatric disturbances. In particular, when fear is the prominent feature the patient may be considered for years as having panic attacks. Eight patients in whom fear was the main symptom of the seizures are reported on. Patients who had a proved lack of consciousness during the fits and patients in whom fear was just fear of having a seizure were excluded. The ictal involvement of temporal limbic and frontal structures in those patients with fear of particular intensity was studied. METHODS: The localisation of the epileptogenic zone was assessed by prolonged interictal EEG recordings as well as ictal video-EEG recording of at least one seizure in every patient; five had ictal SPECT and four had chronic stereotactic implantation of depth electrodes (SEEG). In six patients, a cortical resection was performed with an Engel's class 1 outcome (minimum 28 months follow up, except for two patients). RESULTS: Localisations of primary epileptogenic zones were right temporal in three patients, left temporal in three, bitemporal in one, and frontal in one. In all cases, diagnosis of epileptic seizures could be clinically evoked because of the stereotypy of fits and of associated symptoms. The association of a fear sensation, autonomic symptoms, and coordinated behaviour suggests disturbance of a particular system. The SEEG data argue for temporolimbic and prefrontal lobe involvement in the expression of ictal fear. CONCLUSIONS: In intense ictal fear, with coordinated behaviour and autonomic features, the discharge may involve or interfere with a physiological complex information processing network. This network involves orbitoprefrontal, anterior cingulate, and temporal limbic cortices.

Published
2001

9. Contributo dei procedimenti neuroradiologici stereotassici e dell'esame di risonanza magnetica nello studio anatomico 'in vivo' dei solchi e circonvoluzioni cerebrali

Author

Musolino, A., Scarabin, J.M., Cambria, M., Rizzo, G., Misitano, G., Manti, G., Vitalone, F., Falcone, F., Cambria, S., Musolino, A., Scarabin, J.M., Cambria, M., Rizzo, G., Misitano, G., Manti, G., Vitalone, F., Falcone, F., and Cambria, S.

Abstract

Contribution of stereotactic neuro-radiological procedures and of magnetic resonance imaging to the "in vivo" anatomical study of cerebral sulci and convlolutions. M.R.I. allows us to visualize cortical sulci and convolutions. But visualisation doesn't mean precise and reliable identification in all cases, because there is individual variability in these structures and because of the presence of "pli de passage", and secondary and tertiary sulci. . Szika has demonstrated the possibility of defining indirectly the topograpfy of cortical sulci by means of Tele-Stereotactic-Stereoscopic Angiography. Indeed, Three-Dimensional ANgiography permits one to identify deep vascular segments ("laminae vascularis") buried in the sulcal walls of the invaginated cortex, thereby indicating the location, the depth and the direction of a given sulcus. We propose a procedure utilising these same "laminae vascularis" as a guide for directly identifying sulci and convolutions visible on M.R.I. images which are matched against stereotactic films using ventricular (bicoomisural line) and/or vascular landmarks. This procedure, in spite of some factors of errors, provides better anatomical knowledge on spazial organization of sulci and convolutions in living man. Key words: Cerebral cortex, cerebral sulci, "In vivo" anatomical study, Stereotactic Neurosurgery, Stereo-angiography, Magnetic Resonance Imaging.

10. Contributo dei procedimenti neuroradiologici stereotassici e dell'esame di risonanza magnetica nello studio anatomico 'in vivo' dei solchi e circonvoluzioni cerebrali

Author

Musolino, A., Scarabin, J.M., Cambria, M., Rizzo, G., Misitano, G., Manti, G., Vitalone, F., Falcone, F., Cambria, S., Musolino, A., Scarabin, J.M., Cambria, M., Rizzo, G., Misitano, G., Manti, G., Vitalone, F., Falcone, F., and Cambria, S.

Abstract

Contribution of stereotactic neuro-radiological procedures and of magnetic resonance imaging to the "in vivo" anatomical study of cerebral sulci and convlolutions. M.R.I. allows us to visualize cortical sulci and convolutions. But visualisation doesn't mean precise and reliable identification in all cases, because there is individual variability in these structures and because of the presence of "pli de passage", and secondary and tertiary sulci. . Szika has demonstrated the possibility of defining indirectly the topograpfy of cortical sulci by means of Tele-Stereotactic-Stereoscopic Angiography. Indeed, Three-Dimensional ANgiography permits one to identify deep vascular segments ("laminae vascularis") buried in the sulcal walls of the invaginated cortex, thereby indicating the location, the depth and the direction of a given sulcus. We propose a procedure utilising these same "laminae vascularis" as a guide for directly identifying sulci and convolutions visible on M.R.I. images which are matched against stereotactic films using ventricular (bicoomisural line) and/or vascular landmarks. This procedure, in spite of some factors of errors, provides better anatomical knowledge on spazial organization of sulci and convolutions in living man. Key words: Cerebral cortex, cerebral sulci, "In vivo" anatomical study, Stereotactic Neurosurgery, Stereo-angiography, Magnetic Resonance Imaging.

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