335 results on '"Sbardella, E."'
Search Results
2. Predicting postoperative hypocortisolism in patients with non-aldosterone-producing adrenocortical adenoma: a retrospective single-centre study
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Bonaventura, I., Tomaselli, A., Angelini, F., Ferrari, D., De Alcubierre, D., Hasenmajer, V., Sbardella, E., Cozzolino, A., Paganini, A. M., Isidori, A. M., Minnetti, M., and Pofi, R.
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- 2024
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3. Tall stature and gigantism in transition age: clinical and genetic aspects—a literature review and recommendations
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Sada, V., Puliani, G., Feola, T., Pirchio, R., Pofi, R., Sesti, F., De Alcubierre, D., Amodeo, M. E., D’Aniello, F., Vincenzi, L., Gianfrilli, D., Isidori, A. M., Grossman, A. B., and Sbardella, E.
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- 2024
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4. Sellar and parasellar lesions in the transition age: a retrospective Italian multi-centre study
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Feola, T., Pirchio, R.sa, Puliani, G., Pofi, R., Crocco, M., Sada, V., Sesti, F., Verdecchia, F., Gianfrilli, D., Appetecchia, M., Di Iorgi, N., Jaffrain-Rea, M. L., Pivonello, R., Isidori, A. M., Grossman, A. B., and Sbardella, E.
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- 2023
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5. Management of male factor infertility: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS): Endorsing Organization: Italian Society of Embryology, Reproduction, and Research (SIERR)
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Ferlin, A., Calogero, A. E., Krausz, C., Lombardo, F., Paoli, D., Rago, R., Scarica, C., Simoni, M., Foresta, C., Rochira, V., Sbardella, E., Francavilla, S., and Corona, G.
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- 2022
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6. Expected and paradoxical effects of obesity on cancer treatment response
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Gallo, Marco, Adinolfi, Valerio, Barucca, Viola, Prinzi, Natalie, Renzelli, Valerio, Barrea, Luigi, Di Giacinto, Paola, Ruggeri, Rosaria Maddalena, Sesti, Franz, Arvat, Emanuela, Baldelli, Roberto, Arvat, Emanuela, Colao, Annamaria, Isidori, Andrea, Lenzi, Andrea, Baldell, Roberto, Albertelli, M., Attala, D., Bianchi, A., Di Sarno, A., Feola, T., Mazziotti, G., Nervo, A., Pozza, C., Puliani, G., Razzore, P., Ramponi, S., Ricciardi, S., Rizza, L., Rota, F., Sbardella, E., and Zatelli, M. C.
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- 2021
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7. Strong interaction studies with kaonic atoms
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Marton, J., Bazzi, M., Beer, G., Berucci, C., Bosnar, D., Bragadireanu, A. M., Cargnelli, M., Clozza, A., Curceanu, C., d'Uffizi, A., Fiorini, C., Ghio, F., Guaraldo, C., Hayano, R., Iliescu, M., Ishiwatari, T., Iwasaki, M., Sandri, P. Levi, Okada, S., Pietreanu, D., Piscicchia, K., Ponta, T., Quaglia, R., Vidal, A. Romero, Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
The strong interaction of antikaons with nucleons and nuclei in the low-energy regime represents an active research field connected intrinsically with few-body physics. There are important open questions like the question of antikaon nuclear bound states. A unique and rather direct experimental access to the antikaon-nucleon scattering lengths is provided by precision X-ray spectroscopy of transitions in low-lying states of light kaonic atoms like kaonic hydrogen isotopes. In the SIDDHARTA experiment at the electron-positron collider DAFNE of LNF-INFN we measured the most precise values of the strong interaction observables, i.e. the strong interaction on the 1s ground state of the electromagnetically bound kaonic hydrogen atom leading to a hadronic shift and a hadronic broadening of the 1s state. The SIDDHARTA result triggered new theoretical work which achieved major progress in the understanding of the low-energy strong interaction with strangeness. Antikaon-nucleon scattering lengths have been calculated constrained by the SIDDHARTA data on kaonic hydrogen. For the extraction of the isospin-dependent scattering lengths a measurement of the hadronic shift and width of kaonic deuterium is necessary. Therefore, new X-ray studies with the focus on kaonic deuterium are in preparation (SIDDHARTA2). Many improvements in the experimental setup will allow to measure kaonic deuterium which is challenging due to the anticipated low X-ray yield. Especially important are the data on the X-ray yields of kaonic deuterium extracted from a exploratory experiment within SIDDHARTA., Comment: 4 pages, 2 figures
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- 2016
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8. $K$-series X-ray yield measurement of kaonic hydrogen atoms in a gaseous target
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Bazzi, M., Beer, G., Bellotti, G., Berucci, C., Bragadireanu, A. M., Bosnar, D., Cargnelli, M., Curceanu, C., Butt, A. D., d'Uffizi, A., Fiorini, C., Ghio, F., Guaraldo, C., Hayanao, R. S., Iliescu, M., Ishiwatari, T., Iwasaki, M., Sandri, P. Levi, Marton, J., Okada, S., Pietreanu, D., Piscicchia, K., Vidal, A. Romero, Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
We measured the $K$-series X-rays of the $K^{-}p$ exotic atom in the SIDDHARTA experiment with a gaseous hydrogen target of 1.3 g/l, which is about 15 times the $\rho_{\rm STP}$ of hydrogen gas. At this density, the absolute yields of kaonic X-rays, when a negatively charged kaon stopped inside the target, were determined to be 0.012$^{+0.004}_{-0.003}$ for $K_{\alpha}$ and 0.043$^{+0.012}_{-0.011}$ for all the $K$-series transitions $K_{tot}$. These results, together with the KEK E228 experiment results, confirm for the first time a target density dependence of the yield predicted by the cascade models, and provide valuable information to refine the parameters used in the cascade models for the kaonic atoms., Comment: 9 pages, 5 figures. Submitted to Nuclear Physics A, Special Issue on Strangeness and Charm
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- 2016
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9. Application of photon detectors in the VIP2 experiment to test the Pauli Exclusion Principle
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Pichler, A., Bartalucci, S., Bazzi, M., Bertolucci, S., Berucci, C., Bragadireanu, M., Cargnelli, M., Clozza, A., Curceanu, C., De Paolis, L., Di Matteo, S., D'Uffizi, A., Egger, J. -P., Guaraldo, C., Iliescu, M., Ishiwatari, T., Laubenstein, M., Marton, J., Milotti, E., Pietreanu, D., Piscicchia, K., Ponta, T., Sbardella, E., Scordo, A., Shi, H., Sirghi, D., Sirghi, F., Sperandio, L., Vazquez-Doce, O., Widmann, E., and Zmeskal, J.
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Physics - Instrumentation and Detectors - Abstract
The Pauli Exclusion Principle (PEP) was introduced by the austrian physicist Wolfgang Pauli in 1925. Since then, several experiments have checked its validity. From 2006 until 2010, the VIP (VIolation of the Pauli Principle) experiment took data at the LNGS underground laboratory to test the PEP. This experiment looked for electronic 2p to 1s transitions in copper, where 2 electrons are in the 1s state before the transition happens. These transitions violate the PEP. The lack of detection of X-ray photons coming from these transitions resulted in a preliminary upper limit for the violation of the PEP of $4.7 \times 10^{-29}$. Currently, the successor experiment VIP2 is under preparation. The main improvements are, on one side, the use of Silicon Drift Detectors (SDDs) as X-ray photon detectors. On the other side an active shielding is implemented, which consists of plastic scintillator bars read by Silicon Photomultipliers (SiPMs). The employment of these detectors will improve the upper limit for the violation of the PEP by around 2 orders of magnitude.
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- 2016
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10. VIP 2: Experimental tests of the Pauli Exclusion Principle for electrons
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Pichler, A., Bartalucci, S., Bazzi, M., Bertolucci, S., Berucci, C., Bragadireanu, M., Cargnelli, M., Clozza, A., Curceanu, C., De Paolis, L., Di Matteo, S., D'Uffizi, A., Egger, J. -P., Guaraldo, C., Iliescu, M., Ishiwatari, T., Laubenstein, M., Marton, J., Milotti, E., Pietreanu, D., Piscicchia, K., Ponta, T., Sbardella, E., Scordo, A., Shi, H., Sirghi, D., Sirghi, F., Sperandio, L., Vazquez-Doce, O., Widmann, E., and Zmeskal, J.
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Physics - Instrumentation and Detectors - Abstract
The Pauli Exclusion Principle (PEP) was famously discovered in 1925 by the austrian physicist Wolfgang Pauli. Since then, it underwent several experimental tests. Starting in 2006, the VIP (Violation of the Pauli Principle) experiment looked for 2p to 1s X-ray transitions in copper, where 2 electrons are present in the 1s state before the transition happens. These transitions violate the PEP, and the lack of detection of the corresponding X-ray photons lead to a preliminary upper limit for the violation of the PEP of 4.7 * 10^(-29). The follow-up experiment VIP 2 is currently in the testing phase and will be transported to its final destination, the underground laboratory of Gran Sasso in Italy, in autumn 2015. Several improvements compared to its predecessor like the use of new X-ray detectors and active shielding from background gives rise to a goal for the improvement of the upper limit of the probability for the violation of the Pauli Exclusion Principle of 2 orders of magnitude.
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- 2016
11. Spontaneously emitted X-rays: an experimental signature of the dynamical reduction models
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Curceanu, C., Bartalucci, S., Bassi, A., Bazzi, M., Bertolucci, S., Berucci, C., Bragadireanu, A. M., Cargnelli, M., Clozza, A., De Paolis, L., Di Matteo, S., Donadi, S., DUffizi, A., Egger, J-P., Guaraldo, C., Iliescu, M., Ishiwatari, T., Laubenstein, M., Marton, J., Milotti, E., Pichler, A., Pietreanu, D., Piscicchia, K., Ponta, T ., Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Sperandio, L., Doce, O. Vazquez, and Zmeskal, J.
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Quantum Physics ,Physics - Instrumentation and Detectors - Abstract
We present the idea of searching for X-rays as a signature of the mechanism inducing the spontaneous collapse of the wave function. Such a signal is predicted by the continuous spontaneous localization theories, which are solving the "measurement problem" by modifying the Schrodinger equation. We will show some encouraging preliminary results and discuss future plans and strategy., Comment: to be published in Foundation of Physics 2015
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- 2016
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12. Searches for the Violation of Pauli Exclusion Principle at LNGS in VIP(-2) experiment
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Shi, H, Bartalucci, S., Bertolucci, S., Berucci, C., Bragadireanu, A. M., Cargnelli, M., Clozza, A., Curceanu, C., De Paolis, L., Di Matteo, S., d'Uffizi, A., Egger, J. -P., Guaraldo, C., Iliescu, M., Ishiwatari, T., Marton, J., Laubenstein, M., Milotti, E., Pietreanu, D., Piscicchia, K., Ponta, T., Vidal, A. Romero, Sbardella, E., Scordo, A., Sirghi, D. L., Sirghi, F., Sperandio, L., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Physics - Instrumentation and Detectors ,Quantum Physics - Abstract
The VIP (Violation of Pauli exclusion principle) experiment and its follow-up experiment VIP-2 at the Laboratori Nazionali del Gran Sasso (LNGS) search for X-rays from Cu atomic states that are prohibited by the Pauli Exclusion Principle (PEP). The candidate events, if they exist, will originate from the transition of a $2p$ orbit electron to the ground state which is already occupied by two electrons. The present limit on the probability for PEP violation for electron is 4.7 $\times10^{-29}$ set by the VIP experiment. With upgraded detectors for high precision X-ray spectroscopy, the VIP-2 experiment will improve the sensitivity by two orders of magnitude., Comment: 5 pages, 3 figures, 1 table. Conference proceedings for oral presentation at TAUP 2015, Torino
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- 2016
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13. Precision X-ray spectroscopy of kaonic atoms as a probe of low-energy kaon-nucleus interaction
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Shi, H., Bazzi, M., Beer, G., Bellotti, G., Berucci, C., Bragadireanu, A. M., Bosnar, D., Cargnelli, M., Curceanu, C., Butt, A. D., d'Uffizi, A., Fiorini, C., Ghio, F., Guaraldo, C., Hayano, R. S., Iliescu, M., Ishiwatari, T., Iwasaki, M., Sandri, P. Levi, Marton, J., Okada, S., Pietreanu, D., Piscicchia, K., Vidal, A. Romero, Sbardella, E., Scordo, A., Sirghi, D. L., Sirghi, F., Tatsuno, H., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
In the exotic atoms where one atomic $1s$ electron is replaced by a $K^{-}$, the strong interaction between the $K^{-}$ and the nucleus introduces an energy shift and broadening of the low-lying kaonic atomic levels which are determined by only the electromagnetic interaction. By performing X-ray spectroscopy for Z=1,2 kaonic atoms, the SIDDHARTA experiment determined with high precision the shift and width for the $1s$ state of $K^{-}p$ and the $2p$ state of kaonic helium-3 and kaonic helium-4. These results provided unique information of the kaon-nucleus interaction in the low energy limit., Comment: 4 pages, 1 figure, proceedings for oral presentation at the ICNFP2015 conference, Kolymbari, Crete
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- 2016
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14. Strong interaction studies with kaonic atoms
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Marton, J., Bazzi, M., Beer, G., Berucci, C., Bosnar, D., Bragadireanu, A. M., Cargnelli, M., Clozza, A., Curceanu, C., d'Uffizi, A., Fiorini, C., Ghio, F., Guaraldo, C., Hayano, R., Iliescu, M., Ishiwatari, T., Iwasaki, M., Sandri, P. Levi, Okada, S., Pietreanu, D., Piscicchia, K., Ponta, T., Quaglia, R., Vidal, A. Romero, Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
The strong interaction of antikaons (K-) with nucleons and nuclei in the low energy regime represents an active research field connected intrinsically with few-body physics. There are important open questions like the question of antikaon nuclear bound states - the prototype system being K-pp. A unique and rather direct experimental access to the antikaon-nucleon scattering lengths is provided by precision X-ray spectroscopy of transitions in low-lying states of light kaonic atoms like kaonic hydrogen isotopes. In the SIDDHARTA experiment at the electron-positron collider DA?NE of LNF-INFN we measured the most precise values of the strong interaction observables, i.e. the strong interaction on the 1s ground state of the electromagnetically bound K-p atom leading to a hadronic shift and a hadronic broadening of the 1s state. The SIDDHARTA result triggered new theoretical work which achieved major progress in the understanding of the low-energy strong interaction with strangeness. Antikaon-nucleon scattering lengths have been calculated constrained by the SIDDHARTA data on kaonic hydrogen. For the extraction of the isospin-dependent scattering lengths a measurement of the hadronic shift and width of kaonic deuterium is necessary. Therefore, new X-ray studies with the focus on kaonic deuterium are in preparation (SIDDHARTA2). Many improvements in the experimental setup will allow to measure kaonic deuterium which is challenging due to the anticipated low X-ray yield. Especially important are the data on the X-ray yields of kaonic deuterium extracted from a exploratory experiment within SIDDHARTA., Comment: Proc. Few Body 21, 4 pages, 2 figures
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- 2015
15. VIP 2: Experimental tests of the Pauli Exclusion Principle for electrons
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Pichler, A., Bartalucci, S., Bertolucci, S., Berucci, C., Bragadireanu, M., Cargnelli, M., Clozza, A., Curceanu, C., De Paolis, L., Di Matteo, S., D`Uffizi, A., Egger, J. P., Guaraldo, C., Iliescu, M., Ishiwatari, T., Laubenstein, M., Marton, J., Milotti, E., Pietreanu, D., Piscicchia, K., Ponta, T., Sbardella, E., Scordo, A., Shi, H., Sirghi, D., Sirghi, F., Sperandio, L., Vazquez-Doce, O., Widmann, E., and Zmeskal, J.
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Physics - Instrumentation and Detectors ,Quantum Physics - Abstract
Many experiments investigated the violation of the Pauli Exclusion Principle (PEP) since its discovery in 1925. The VIP (VIolation of the Pauli Principle) experiment tested the PEP by measuring the probability for an external electron to be captured and undergo a 2p to 1s transition during its cascading process, where the 1s state is already occupied by two electrons. This transition is forbidden by the Pauli Exclusion Principle. The VIP experiment resulted in a preliminary upper limit for the probability of the violation of the PEP of 4.7 x 10^{-29}. Currently a setup for the follow-up experiment VIP 2 is under preparation. The goal of this experiment is to improve the upper limit for the violation of the PEP by two orders of magnitude, by different improvements like enhanced energy resolution of the X-ray detectors and by implementing an active shielding. Here we report currently ongoing performance tests of the new parts of the setup., Comment: EXA 2014 proceedings in Hyperfine Interactions (2015), Springer International Publishing
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- 2015
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16. Unprecedented studies of the low-energy negatively charged kaons interactions in nuclear matter by AMADEUS
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Curceanu, C., Piscicchia, K., Bazzi, M., Berucci, C., Bosnar, D., Bragadireanu, A. M., Clozza, A., Cargnelli, M., D'uffizi, A., Fabbietti, L., Fiorini, C., Ghio, F., Guaraldo, C., Iliescu, M., Sandri, P. Levi, Marton, J., Pietreanu, D., Lener, M. Poli, Quaglia, R., Vidal, A. Romero, Sbardella, E., Scordo, A., Shi, H., Sirghi, D., Sirghi, F., Skurzok, M., Tucakovic, I., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
The AMADEUS experiment aims to provide unique quality data of $K^-$ hadronic interactions in light nuclear targets, in order to solve fundamental open questions in the non-perturbative strangeness QCD sector, like the controversial nature of the $\Lambda(1405)$ state, the yield of hyperon formation below threshold, the yield and shape of multi-nucleon $K^-$ absorption, processes which are intimately connected to the possible existence of exotic antikaon multi-nucleon clusters. AMADEUS takes advantage of the DA$\Phi$NE collider, which provides a unique source of monochromatic low-momentum kaons and exploits the KLOE detector as an active target, in order to obtain excellent acceptance and resolution data for $K^-$ nuclear capture on H, ${}^4$He, ${}^{9}$Be and ${}^{12}$C, both at-rest and in-flight. During the second half of 2012 a successful data taking was performed with a dedicated pure carbon target implemented in the central region of KLOE, providing a high statistic sample of pure at-rest $K^-$ nuclear interactions. For the future dedicated setups involving cryogenic gaseous targets are under preparation., Comment: 14 pages, 6 figures
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- 2015
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17. Measurement of the strong interaction induced shift and width of the 1s state of kaonic deuterium at J-PARC
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Zmeskal, J., Sato, M., Ajimura, S., Bazzi, M., Beer, G., Berucci, C., Bhang, H., Bosnar, D., Bragadireanu, M., Buehler, P., Busso, L., Cargnelli, M., Choi, S., Clozza, A., Curceanu, C., D'uffizi, A., Enomoto, S., Fabbietti, L., Faso, D., Fiorini, C., Fujioka, H., Ghio, F., Golser, R., Guaraldo, C., Hashimoto, T., Hayano, R. S., Hiraiwa, T., Iio, M., Iliescu, M., Inoue, K., Ishimoto, S., Ishiwatari, T., Itahashi, K., Iwai, M., Iwasaki, M., Kawasaki, S., Lachner, J., Sandri, P. Levi, Ma, Y., Marton, J., Matsuda, Y., Mizoi, Y., Morra, O., Moskal, P., Nagae, T., Noumi, H., Ohnishi, H., Okada, S., Outa, H., Pietreanu, D., Piscicchia, K., Lener, M. Poli, Vidal, A. Romero, Sada, Y., Sakaguchi, A., Sakuma, F., Sbardella, E., Scordo, A., Sekimoto, M., Shi, H., Silarski, M., Sirghi, D., Sirghi, F., Suzuki, K., Suzuki, S., Suzuki, T., Tanida, K., Tatsuno, H., Tokuda, M., Toyoda, A., Tucakovic, I., Tsukada, K., Doce, O. Vazquez, Widmann, E., Yamaga, T., Yamazaki, T., and Zhang, Q.
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Nuclear Experiment ,Physics - Instrumentation and Detectors - Abstract
The antikaon-nucleon interaction close to threshold provides crucial information on the interplay between spontaneous and explicit chiral symmetry breaking in low-energy QCD. In this context the importance of kaonic deuterium X-ray spectroscopy has been well recognized, but no experimental results have yet been obtained due to the difficulty of the measurement. We propose to measure the shift and width of the kaonic deuterium 1s state with an accuracy of 60 eV and 140 eV respectively at J-PARC. These results together with the kaonic hydrogen data (KpX at KEK, DEAR and SIDDHARTA at DAFNE) will then permit the determination of values of both the isospin I=0 and I=1 antikaon-nucleon scattering lengths and will provide the most stringent constraints on the antikaon-nucleon interaction, promising a breakthrough. Refined Monte Carlo studies were performed, including the investigation of background suppression factors for the described setup. These studies have demonstrated the feasibility of determining the shift and width of the kaonic deuterium atom 1s state with the desired accuracy of 60 eV and 140 eV., Comment: 12 pages, 9 figures
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- 2015
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18. Beyond quantum mechanics? Hunting the 'impossible' atoms (Pauli Exclusion Principle violation and spontaneous collapse of the wave function at test)
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Piscicchia, K., Curceanu, C., Bartalucci, S., Bassi, A., Bertolucci, S., Berucci, C., Bragadireanu, A. M., Cargnelli, M., Clozza, A., De Paolis, L., Di Matteo, S., Donadi, S., d'Uffizi, A., Egger, J-P., Guaraldo, C., Iliescu, M., Ishiwatari, T., Laubenstein, M., Marton, J., Milotti, E., Pietreanu, D., Ponta, T., Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Sperandio, L., Doce, O. Vazquez, and Zmeskal, J.
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Quantum Physics ,Physics - Instrumentation and Detectors - Abstract
The development of mathematically complete and consistent models solving the so-called "measurement problem", strongly renewed the interest of the scientific community for the foundations of quantum mechanics, among these the Dynamical Reduction Models posses the unique characteristic to be experimentally testable. In the first part of the paper an upper limit on the reduction rate parameter of such models will be obtained, based on the analysis of the X-ray spectrum emitted by an isolated slab of germanium and measured by the IGEX experiment. The second part of the paper is devoted to present the results of the VIP (Violation of the Pauli exclusion principle) experiment and to describe its recent upgrade. The VIP experiment established a limit on the probability that the Pauli Exclusion Principle (PEP) is violated by electrons, using the very clean method of searching for PEP forbidden atomic transitions in copper.
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- 2015
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19. Testing the Pauli Exclusion Principle for electrons at LNGS
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Shi, H., Bartalucci, S., Bertolucci, S., Berucci, C., Bragadireanu, A. M., Cargnelli, M., Clozza, A., Curceanu, C., De Paolis, L., Di Matteo, S., d'Uffizi, A., Egger, J. -P., Guaraldo, C., Iliescu, M., Ishiwatari, T., Marton, J., Laubenstein, M., Milotti, E., Pietreanu, D., Piscicchia, K., Ponta, T., Vidal, A. Romero, Sbardella, E., Scordo, A., Sirghi, D. L., Sirghi, F., Sperandio, L., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Quantum Physics ,Physics - Instrumentation and Detectors - Abstract
High-precision experiments have been done to test the Pauli exclusion principle (PEP) for electrons by searching for anomalous $K$-series X-rays from a Cu target supplied with electric current. With the highest sensitivity, the VIP (VIolation of Pauli Exclusion Principle) experiment set an upper limit at the level of $10^{-29}$ for the probability that an external electron captured by a Cu atom can make the transition from the 2$p$ state to a 1$s$ state already occupied by two electrons. In a follow-up experiment at Gran Sasso, we aim to increase the sensitivity by two orders of magnitude. We show proofs that the proposed improvement factor is realistic based on the results from recent performance tests of the detectors we did at Laboratori Nazionali di Frascati (LNF)., Comment: 8 pages, 5 figures, conference proceedings on TAUP 2013
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- 2014
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20. Malignant cerebral infarction after ChAdOx1 nCov-19 vaccination: a catastrophic variant of vaccine-induced immune thrombotic thrombocytopenia
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De Michele, M., Iacobucci, M., Chistolini, A., Nicolini, E., Pulcinelli, F., Cerbelli, B., Merenda, E., Schiavo, O. G., Sbardella, E., Berto, I., Petraglia, L., Caracciolo, N., Chiara, M., Truglia, S., and Toni, D.
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- 2021
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21. Predictors of malignancy in high-risk indeterminate (TIR3B) cytopathology thyroid nodules
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Cozzolino, A., Pozza, C., Pofi, R., Sbardella, E., Faggiano, A., Isidori, A. M., Giannetta, E., Pernazza, A., Rullo, E., Ascoli, V., Lenzi, A., and Gianfrilli, D.
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- 2020
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22. COVID-19 infection and glucocorticoids: update from the Italian Society of Endocrinology Expert Opinion on steroid replacement in adrenal insufficiency
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Isidori, A. M., Arnaldi, G., Boscaro, M., Falorni, A., Giordano, C., Giordano, R., Pivonello, R., Pofi, R., Hasenmajer, V., Venneri, M. A., Sbardella, E., Simeoli, C., Scaroni, C., and Lenzi, A.
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- 2020
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23. Thyroid profile during the alternative Sunitinib dosing 2/1 schedule in metastatic renal cell carcinoma
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Rizza, L., Sbardella, E., Gianfrilli, D., Lauretta, R., Tenuta, M., Del Bene, G., Longo, F., Faggiano, A., Lenzi, A., Giannetta, E., and Pozza, C.
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- 2020
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24. X-ray transition yields of low-Z kaonic atoms produced in Kapton
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Bazzi, M., Beer, G., Berucci, C., Bombelli, L., Bragadireanu, A. M., Cargnelli, M., Curceanu, C., d'Uffizi, A., Fiorini, C., Ghio, F., Guaraldo, C., Hayano, R. S., Iliescu, M., Ishiwatari, T., Iwasaki, M., Kienle, P., Sandri, P. Levi, Longoni, A., Marton, J., Okada, S., Pietreanu, D., Ponta, T., Quaglia, R., Vidal, A. Romero, Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Tudorache, A., Tudorache, V., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
The X-ray transition yields of kaonic atoms produced in Kapton polyimide (C22H10N2O5) were measured for the first time in the SIDDHARTA experiment. X-ray yields of the kaonic atoms with low atomic numbers (Z = 6, 7, and 8) and transitions with high principal quantum numbers (n = 5-8) were determined. The relative yield ratios of the successive transitions and those of carbon-to-nitrogen (C:N) and carbon-to-oxygen (C:O) were also determined. These X-ray yields provide important information for understanding the capture ratios and cascade mechanisms of kaonic atoms produced in a compound material, such as Kapton., Comment: Accepted in Nucl. Phys. A (2013)
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- 2013
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25. A GEM-based Time Projection Chamber for the AMADEUS experiment
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Lener, M. Poli, Bazzi, M., Corradi, G., Curceanu, C., D'Uffizi, A., Paglia, C., Sbardella, E., Scordo, A., Tagnani, D., Vidal, A. Romero, and Zmeskal, J.
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Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
In this paper we present the R&D activity on a new GEM-based TPC prototype for AMADEUS, a new experimental proposal at the DA{\Phi}NE {\Phi}-factory at the Laboratori Nazionali di Frascati (INFN), aiming to perform measurements of the low-energy negative kaons interactions in nuclei. Such innovative detector will equip the inner part of the experiment in order to perfom a better reconstruction of the primary vertex and the secondary particles tracking. A 10x10 cm2 prototype with a drift gap up to 15 cm was realized and succesfully tested at the {\pi} M1 beam facility of the Paul Scherrer Institut (PSI) with low momentum hadrons. The measurements of the detector efficiency and spatial resolution have been performed. The results as a function of the gas gain, drift field, front-end electronic threshold and particle momentum are reported and discussed., Comment: 51th International Winter Conference - Bormio 2013
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- 2013
26. Kaon-nuclei interaction studies at low energies (the AMADEUS project)
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Piscicchia, K., Bazzi, M., Berucci, C., Bosnar, D., Bragadireanu, A. M., Cargnelli, M., Clozza, A., Curceanu, C., D'Uffizi, A., Ghio, F., Guaraldo, C., Kienle, P., Iliescu, M., Ishiwatari, T., Sandri, P. Levi, Marton, J., Pietreanu, D., Lener, M. Poli, Rizzo, A., Vidal, A. Romero, Sbardella, E., Scordo, A., Sirghi, D. L., Sirghi, F., Tatsuno, H., Tucakovic, I., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
The AMADEUS experiment aims to perform dedicated precision studies in the sector of low-energy kaon-nuclei interaction at the DA\Phi NE collider at LNF-INFN. In particular the experiment plans to perform measurements of the debated deeply bound kaonic nuclear states (by stopping kaons in cryogenic gaseous targets 3He and 4He) to explore the nature of the \Lambda(1405) in nuclear environment and to measure the cross section of K- on light nuclei, for K- momentum lower than 100 MeV/c. The AMADEUS dedicated setup will be installed in the central region of the KLOE detector., Comment: 3 pages
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- 2013
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27. Performances of a GEM-based Time Projection Chamber prototype for the AMADEUS experiment
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Lener, M. Poli, Bazzi, M., Corradi, G., Curceanu, C., D'Uffizi, A., Paglia, C., Vidal, A. Romero, Sbardella, E., Scordo, A., Tagnani, D., and Zmeskal, J.
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Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
A large number of high-energy and heavy-ion experiments successfully used Time Projection Chamber (TPC) as central tracker and particle identification detector. However, the performance requirements on TPC for new high-rate particle experiments greatly exceed the abilities of traditional TPC read out by multi-wire proportional chamber (MWPC). Gas Electron Multiplier (GEM) detector has great potential to improve TPC performances when used as amplification device. In this paper we present the R&D activity on a new GEM-based TPC detector built as a prototype for the inner part for AMADEUS, a new experimental proposal at the DAFNE collider at Laboratori Nazionali di Frascati (INFN), aiming to perform measurements of the low-energy negative kaons interactions in nuclei. In order to evaluate the GEM-TPC performances, a 10x10 cm2 prototype with a drift gap up to 15 cm has been realized. The detector was tested at the pM1 beam facility of the Paul Scherrer Institut (PSI) with low momentum pions and protons, without magnetic field. Drift properties of argonisobutane gas mixtures are measured and compared withMagboltz prediction. Detection efficiency and spatial resolution as a function of a large number of parameters, such as the gas gain, the drift field, the front-end electronic threshold and particle momentum, are illustrated and discussed. Particle identification capability and the measurement of the energy resolution in isobutane-based gas mixture are also reported.
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- 2013
28. Preliminary study of kaonic deuterium X-rays by the SIDDHARTA experiment at DAFNE
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Bazzi, M., Beer, G., Berucci, C., Bombelli, L., Bragadireanu, A. M., Cargnelli, M., Curceanu, C., d'Uffizi, A., Fiorini, C., Frizzi, T., Ghio, F., Guaraldo, C., Hayano, R., Iliescu, M., Ishiwatari, T., Iwasaki, M., Kienle, P., Sandri, P. Levi, Longoni, A., Marton, J., Okada, S., Pietreanu, D., Ponta, T., Vidal, A. Romero, Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Tudorache, A., Tudorache, V., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
The study of the KbarN system at very low energies plays a key role for the understanding of the strong interaction between hadrons in the strangeness sector. At the DAFNE electron-positron collider of Laboratori Nazionali di Frascati we studied kaonic atoms with Z=1 and Z=2, taking advantage of the low-energy charged kaons from Phi-mesons decaying nearly at rest. The SIDDHARTA experiment used X-ray spectroscopy of the kaonic atoms to determine the transition yields and the strong interaction induced shift and width of the lowest experimentally accessible level (1s for H and D and 2p for He). Shift and width are connected to the real and imaginary part of the scattering length. To disentangle the isospin dependent scattering lengths of the antikaon-nucleon interaction, measurements of Kp and of Kd are needed. We report here on an exploratory deuterium measurement, from which a limit for the yield of the K-series transitions was derived: Y(K_tot)<0.0143 and Y(K_alpha)<0.0039 (CL 90%). Also, the upcoming SIDDHARTA-2 kaonic deuterium experiment is introduced., Comment: Accepted by Nuclear Physics A
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- 2013
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29. Characterization of a scintillating fibers read by MPPC detectors trigger prototype for the AMADEUS experiment
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Scordo, A., Bazzi, M., Berucci, C., Curceanu, C., D'Uffizi, A., Piscicchia, K., Lener, M. Poli, Vidal, A. Romero, Sbardella, E., and Doce, O. Vazquez
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Physics - Instrumentation and Detectors - Abstract
Multi-Pixel Photon Counters (MPPC) consist of hundreds of micro silicon Avalanche PhotoDiodes (APD) working in Geiger mode. The high gain and the low noise, typical of these devices, together with their good performance in magnetic field, make them ideal readout detectors for scintillating fibers as trigger detectors in particle and nuclear physics experiments like AMADEUS, where such detectors are planned to be used to trigger on charged kaon pairs. In order to investigate the detection efficiency of such a system, a prototype setup consisting of 32, 1 mm diameter scintillating fibers, arranged in two double layers of 16 fibers each, and read out by 64 MPPCs with an ad-hoc built readout electronics, was tested at the piM-1 line of the Paul Scherrer Institute (PSI) in Villigen, Switzerland. The detection efficiency and the trigger capability were measured on a beam containing protons, electrons, muons and pions with a momentum of 440 MeV/c. The measured average efficiency for protons for a double layer of scintillating fibers (96.9 +/-1.2%) represents a guarantee of the good performance of this system as a trigger for the AMADEUS experiment., Comment: 9 pages, 9 figures, 2 tables, sent to JINST for publication
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- 2013
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30. Measurements of the strong-interaction widths of the kaonic 3He and 4He 2p levels
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The SIDDHARTA collaboration, Bazzi, M., Beer, G., Bombelli, L., Bragadireanu, A. M., Cargnelli, M., Curceanu, C., d'Uffizi, A., Fiorini, C., Frizzi, T., Ghio, F., Guaraldo, C., Hayano, R. S., Iliescu, M., Ishiwatari, T., Iwasaki, M., Kienle, P., Sandri, P. Levi, Longoni, A., Marton, J., Okada, S., Pietreanu, D., Ponta, T., Rizzo, A., Vidal, A. Romero, Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Tudorache, A., Tudorache, V., Doce, O. Vazquez, Wunschek, B., Widmann, E., and Zmeskal, J.
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Nuclear Experiment - Abstract
The kaonic 3He and 4He X-rays emitted in the 3d-2p transitions were measured in the SIDDHARTA experiment. The widths of the kaonic 3He and 4He 2p states were determined to be Gamma_2p(3He) = 6 \pm 6 (stat.) \pm 7 (syst.) eV, and Gamma_2p(4He) = 14 \pm 8 (stat.) \pm 5 (syst.) eV, respectively. Both results are consistent with the theoretical predictions. The width of kaonic 4He is much smaller than the value of 55 \pm 34 eV determined by the experiments performed in the 70's and 80's, while the width of kaonic 3He was determined for the first time., Comment: Accepted in Phys. Lett. B
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- 2012
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31. Towards the tailoring of glucocorticoid replacement in adrenal insufficiency: the Italian Society of Endocrinology Expert Opinion
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Isidori, A. M., Arnaldi, G., Boscaro, M., Falorni, A., Giordano, C., Giordano, R., Pivonello, R., Pozza, C., Sbardella, E., Simeoli, C., Scaroni, C., and Lenzi, A.
- Abstract
Context: Glucocorticoid (GC) replacement therapy in patients with adrenal insufficiency (AI) is life saving. After over 50 years of conventional GC treatment, novel formulations are now entering routine clinical practice. Methods: Given the spectrum of medications currently available and new insights into the understanding of AI, the authors reviewed relevant medical literature with emphasis on original studies, prospective observational data and randomized controlled trials performed in the past 35 years. The Expert Opinion of a panel of selected endocrinologists was sought to answer specific clinical questions. The objective was to provide an evidence-supported guide, for the use of GC in various settings from university hospitals to outpatient clinics, that offers specific advice tailored to the individual patient. Results: The Panel reviewed available GC replacement therapies, comprising short-acting, intermediate and long-acting oral formulations, subcutaneous formulations and the novel modified-release hydrocortisone. Advantages and disadvantages of these formulations were reviewed. Conclusions: In the Panel’s opinion, achieving the optimal GC timing and dosing is needed to improve the outcome of AI. No-single formulation offers the best option for every patients. Recent data suggest that more emphasis should be given to the timing of intake. Tailoring of GS should be attempted in all patients—by experts—on a case-by-case basis. The Panel identified specific subgroups of AI patients that could be help by this process. Long-term studies are needed to confirm the short-term benefits associated with the modified-release GCs. The impact of GC tailoring has yet to be proven in terms of hospitalization rate, morbidity and mortality.
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- 2024
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32. Predictors of malignancy in high-risk indeterminate (TIR3B) cytopathology thyroid nodules
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Cozzolino, A., Pozza, C., Pofi, R., Sbardella, E., Faggiano, A., Isidori, A. M., Giannetta, E., Pernazza, A., Rullo, E., Ascoli, V., Lenzi, A., and Gianfrilli, D.
- Abstract
Purpose: The classification of indeterminate cytopathology at thyroid fine-needle-aspiration (FNA) has been updated to reduce the number of unnecessary surgery; the 2014 Italian classification introduced the low-risk (TIR3A) and high-risk (TIR3B) subcategories. Aim of this study was to identify the ultrasonographic (US), clinical and cytological predictors of malignancy among TIR3B nodules from a single institution. Methods: A prospective observational study including 1844 patients who underwent thyroid FNA from June 2014 to January 2019. Ultrasonographic, clinical and cytological features were recorded. All TIR3B diagnoses were referred to surgery. According to final histology, patients were divided into thyroid cancer (TC) or benign nodules. Chi-square test, or Fisher exact test when appropriate, were used to compare groups and logistic regression analyses were used to determine independent predictors of malignancy. Results: Of 1844 FNAs, 96 (5.2%) were TIR3B. Histology report was available in 65. Among them, 25 (38.5%) were TC. Predictors of TC were nodule size < 20 mm [Odds Ratio (OR) = 5.88, 95% CI 1.91–18.11, p= 0.002], absence or weak intralesional flow [OR = 0.3, 95% CI 0.09–0.77, p= 0.015], microcalcifications [OR = 6.5, 95% CI 1.90–21.93, p= 0.003] at US; nuclear inclusions [OR = 25.3, 95% CI 1.34–476.07, p= 0.031] and chromatin clearing [OR = 3.7, 95% CI 1.27–10.99, p= 0.017] at cytopathology. Patients aged < 55 years had a significantly higher risk of TC [OR = 9.7, 95% CI 2.79–34.07, p< 0.001]. In multivariate analysis, age < 55 and nodule size < 20 mm resulted as independent risk factors. Conclusions: Patients < 55 years receiving a diagnosis TIR3B on nodules < 20 mm, with microcalcifications, showing specific nuclear atypia at cytopathology are more likely to have TC. Combining US, cytological and clinical features could help determining which patients with a TIR3B diagnosis should be referred to surgery.
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- 2024
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33. K-series X-ray yield measurement of kaonic hydrogen atoms in a gaseous target
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Bazzi, M., Beer, G., Bellotti, G., Berucci, C., Bragadireanu, A.M., Bosnar, D., Cargnelli, M., Curceanu, C., Butt, A.D., d'Uffizi, A., Fiorini, C., Ghio, F., Guaraldo, C., Hayano, R.S., Iliescu, M., Ishiwatari, T., Iwasaki, M., Levi Sandri, P., Marton, J., Okada, S., Pietreanu, D., Piscicchia, K., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Sirghi, D.L., Sirghi, F., Tatsuno, H., Vazquez Doce, O., Widmann, E., and Zmeskal, J.
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- 2016
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34. Approach to hyponatremia according to the clinical setting: Consensus statement from the Italian Society of Endocrinology (SIE), Italian Society of Nephrology (SIN), and Italian Association of Medical Oncology (AIOM)
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Sbardella, E., Isidori, A. M., Arnaldi, G., Arosio, M., Barone, C., Benso, A., Berardi, R., Capasso, G., Caprio, M., Ceccato, F., Corona, G., Della Casa, S., De Nicola, L., Faustini-Fustini, M., Fiaccadori, E., Gesualdo, L., Gori, S., Lania, A., Mantovani, G., Menè, P., Parenti, G., Pinto, C., Pivonello, R., Razzore, P., Regolisti, G., Scaroni, C., Trepiccione, F., Lenzi, A., Peri, A., and On behalf of the: Fluid and Electrolyte Disorders Club of the Italian Society of Endocrinology; Italian Society of Nephrology; and Italian Association of Medical Oncology
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- 2017
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35. Testing the Pauli Exclusion Principle for Electrons at LNGS
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Shi, H., Bartalucci, S., Bertolucci, S., Berucci, C., Bragadireanu, A.M., Cargnelli, M., Clozza, A., Curceanu, C., De Paolis, L., Di Matteo, S., d’Uffizi, A., Egger, J.-P., Guaraldo, C., Iliescu, M., Ishiwatari, T., Marton, J., Laubenstein, M., Milotti, E., Pietreanu, D., Piscicchia, K., Ponta, T., Vidal, A. Romero, Sbardella, E., Scordo, A., Sirghi, D.L., Sirghi, F., Sperandio, L., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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- 2015
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36. Studies of the interaction at DAΦNE
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Vázquez Doce, O., Bazzi, M., Berucci, C., Bombelli, L., Bragadireanu, A. M., Cargnelli, M., Clozza, A., Curceanu (Petrascu), C., d’Uffizi, A., Fiorini, C., Ghio, F., Guaraldo, C., Iliescu, M., Ishiwatari, T., Sandri, P. Levi, Longoni, A., Marton, J., Okada, S., Pietreanu, D., Piscicchia, K., Poli Lener, M., Ponta, T., Rizzo, A., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Widmann, E., Zmeskal, J., Bühler, Paul, editor, Hartmann, Olaf, editor, Marton, Johann, editor, Suzuki, Ken, editor, Widmann, Eberhard, editor, and Zmeskal, Johann, editor
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- 2012
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37. Kaonic 3He and 4He X-ray measurements in SIDDHARTA
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Ishiwatari, Tomoichi, Bazzi, M., Beer, G., Berucci, C., Bombelli, L., Bragadireanu, A. M., Cargnelli, M., Clozza, A., Corradi, G., Curceanu (Petrascu), C., d’Uffizi, A., Fiorini, C., Ghio, F., Girolami, B., Guaraldo, C., Hayano, R. S., Iliescu, M., Iwasaki, M., Kienle, P., Levi Sandri, P., Lucherini, V., Marton, J., Okada, S., Pietreanu, D., Piscicchia, K., Poli Lener, M., Ponta, T., Quaglia, R., Rizzo, A., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Tudorache, A., Tudorache, V., Vazquez Doce, O., Widmann, E., Wünschek, B., Zmeskal, J., Bühler, Paul, editor, Hartmann, Olaf, editor, Marton, Johann, editor, Suzuki, Ken, editor, Widmann, Eberhard, editor, and Zmeskal, Johann, editor
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- 2012
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38. Results from the kaonic hydrogen X-ray measurement at DAFNE and outlook to future experiments
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Cargnelli, Michael, Bazzi, M., Beer, G., Berucci, C., Bombelli, L., Bragadireanu, A. M., Clozza, A., Corradi, G., Curceanu (Petrascu), C., d’Uffizi, A., Fiorini, C., Ghio, F., Girolami, B., Guaraldo, C., Hayano, R. S., Iliescu, M., Ishiwatari, T., Iwasaki, M., Kienle, P., Levi Sandri, P., Lucherini, V., Marton, J., Okada, S., Pietreanu, D., Piscicchia, K., Poli Lener, M., Ponta, T., Quaglia, R., Rizzo, A., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Tudorache, A., Tudorache, V., Vazquez Doce, O., Widmann, E., Zmeskal, J., Bühler, Paul, editor, Hartmann, Olaf, editor, Marton, Johann, editor, Suzuki, Ken, editor, Widmann, Eberhard, editor, and Zmeskal, Johann, editor
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- 2012
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39. Prevalence and severity of non‐alcoholic fatty liver disease are underestimated in clinical practice: impact of a dedicated screening approach at a large university teaching hospital
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Marjot, T., Sbardella, E., Moolla, A., Hazlehurst, J. M., Tan, G. D., Ainsworth, M., Cobbold, J. F. L., and Tomlinson, J. W.
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- 2018
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40. Unlocking the secrets of the kaon–nucleon/nuclei interactions at low-energies: The SIDDHARTA(-2) and the AMADEUS experiments at the DAΦNE collider
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Curceanu, C., Bazzi, M., Beer, G., Berucci, C., Bombelli, L., Bragadireanu, A.M., Cargnelli, M., Clozza, A., dʼUffizi, A., Fiorini, C., Frizzi, T., Ghio, F., Guaraldo, C., Hayano, R.S., Iliescu, M., Ishiwatari, T., Iwasaki, M., Kienle, P., Levi Sandri, P., Longoni, A., Marton, J., Okada, S., Pietreanu, D., Piscicchia, K., Poli Lener, M., Ponta, T., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Sirghi, D.L., Sirghi, F., Tatsuno, H., Tudorache, A., Tudorache, V., Vazquez Doce, O., Widmann, E., Wünschek, B., and Zmeskal, J.
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- 2013
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41. Strong-interaction shifts and widths of kaonic helium isotopes
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Ishiwatari, T., Bazzi, M., Beer, G., Bombelli, L., Bragadireanu, A.M., Cargnelli, M., Curceanu (Petrascu), C., dʼUffizi, A., Fiorini, C., Frizzi, T., Ghio, F., Guaraldo, C., Hayano, R.S., Iliescu, M., Iwasaki, M., Kienle, P., Levi Sandri, P., Longoni, A., Marton, J., Okada, S., Pietreanu, D., Ponta, T., Rizzo, A., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Sirghi, D.L., Sirghi, F., Tatsuno, H., Tudorache, A., Tudorache, V., Vazquez Doce, O., Widmann, E., Wünschek, B., and Zmeskal, J.
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- 2013
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42. Carotid artery stenting during endovascular thrombectomy for acute ischemic stroke with tandem occlusion: the Italian Registry of Endovascular Treatment in Acute Stroke
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Sallustio, Fabrizio, Pracucci, Giovanni, Cappellari, Manuel, Saia, Valentina, Mascolo, Alfredo Paolo, Marrama, Federico, Gandini, Roberto, Koch, Giacomo, Diomedi, Marina, D’Agostino, Federica, Rocco, Alessandro, Da Ros, Valerio, Wlderk, Andrea, Nezzo, Marco, Argirò, Renato, Morosetti, Daniele, Renieri, Leonardo, Nencini, Patrizia, Vallone, Stefano, Zini, Andrea, Bigliardi, Guido, Pitrone, Antonio, Grillo, Francesco, Bracco, Sandra, Tassi, Rossana, Bergui, Mauro, Naldi, Andrea, Carità, Giuseppe, Casetta, Ilaria, Gasparotti, Roberto, Magoni, Mauro, Simonetti, Luigi, Haznedari, Nicolò, Paolucci, Matteo, Mavilio, Nicola, Malfatto, Laura, Menozzi, Roberto, Genovese, Antonio, Cosottini, Mirco, Orlandi, Giovanni, Comai, Alessio, Franchini, Enrica, Pedicelli, Alessandro, Frisullo, Giovanni, Puglielli, Edoardo, Casalena, Alfonsina, Cester, Giacomo, Baracchini, Claudio, Castellano, Davide, Di Liberto, Alessandra, Ricciardi, Giuseppe Kenneth, Chiumarulo, Luigi, Petruzzellis, Marco, Lafe, Elvis, Persico, Alessandra, Cavasin, Nicola, Critelli, Adriana, Semeraro, Vittorio, Tinelli, Angelica, Giorgianni, Andrea, Carimati, Federico, Auteri, William, Rizzuto, Stefano, Biraschi, Francesco, Nicolini, Ettore, Ferrari, Antonio, Melis, Maurizio, Calia, Stefano, Tassinari, Tiziana, Nuzzi, Nunzio Paolo, Corato, Manuel, Sacco, Simona, Squassina, Guido, Invernizzi, Paolo, Gallesio, Ivan, Ruiz, Luigi, Dui, Giovanni, Carboni, Nicola, Amistà, Pietro, Russo, Monia, Maiore, Mario, Zanda, Bastianina, Craparo, Giuseppe, Mannino, Marina, Inzitari, Domenico, Toni, Danilo, Mangiafico, Salvatore, Gasparotti, R., Inzitari, D., Mangiafico, S., Toni, D., Vallone, S., Zini, A., Bergui, M., Causin, F., Ciccone, A., Nencini, P., Saletti, A., Sallustio, F., Tassi, R., Thyrion, F. Zappoli, Pracucci, G., Saia, V., Gandini, R., Da Ros, V., Greco, L., Morosetti, D., Diomedi, M., Nappini, S., Limbucci, N., Renieri, L., Fainardi, E., Verganti, L., Sacchetti, F., Zelent, G., Bigliardi, G., Dell’Acqua, M. L., Picchetto, L., Vandelli, L., Pentore, R., Maffei, S., Nichelli, P., Longo, M., Pitrone, A., Vinci, S. L., Velo, M., Caragliano, A., Tessitore, A., Bonomo, O., Musolino, R., La Spina, P., Casella, C., Fazio, M. C., Grillo, F., Cotroneo, M., Dell’Aera, C., Francalanza, I., Bracco, S., Cioni, S., Gennari, P., Vallone, I. M., Cerase, A., Martini, G., Stura, G., Daniele, D., Cerrato, P., Naldi, A., Onofrio, M., De Vito, A., Azzini, C., Casetta, I., Mardighian, D., Frigerio, M., Magoni, M., Costa, A., Simonetti, L., Cirillo, L., Taglialatela, F., Isceri, S., Princiotta, C., Dall’Olio, M., Cellerini, M., Gentile, M., Piccolo, L., Migliaccio, L., Brancaleoni, L., Naldi, F., Romoli, M., Zaniboni, A., Ruggiero, M., Sanna, A., Haznedari, N., Commodaro, C., Longoni, M., Biguzzi, S., Cordici, F., Malatesta, E., Castellan, L., Mavilio, N., Salsano, G., Malfatto, L., Finocchi, C., Menozzi, R., Piazza, P., Epifani, E., Andreone, A., Scoditti, U., Castellini, P., Latte, L., Grisendi, I., Cosottini, M., Puglioli, M., Lazzarotti, G., Lauretti, D., Mancuso, M., Giannini, N., Maccarone, M., Orlandi, G., Comai, A., Bonatti, G., Nano, G., Ferro, F., Bonatti, M., Dall’Ora, E., Dossi, R. Currò, Turri, E., Turri, M., Colosimo, C., Pedicelli, A., D’Argento, F., Alexandre, A., Frisullo, G., Di Egidio, V., Puglielli, E. G., Ruggero, L., Assetta, M., Casalena, A., Cester, G., Baracchini, C., Viaro, F., Pieroni, A., Vaudano, G., Comelli, C., Di Maggio, L., Castellano, D., Cavallo, R., Duc, E., Chianale, G., Ciceri, E. F. M., Plebani, M., Augelli, R., Zampieri, P., Grazioli, A., Cappellari, M., Forlivesi, S., Tomelleri, G., Micheletti, N., Chiumarulo, L., Zimatore, D. S., Federico, F., Petruzzelli, M., Zappoli, F., Lafe, E., Sanfilippo, G., Sgreccia, A., Martignoni, A., Cavallini, A., Denaro, F., Persico, A., Cagliari, E., Cavasin, N., Quatrale, R., Critelli, A., Burdi, N., Semeraro, V., Lucarelli, N., Ganimede, M. P., Internò, S., Tinelli, A., Prontera, M. P., Pesare, A., Cotroneo, E., Pampana, E., Ricciardi, F., Gigli, R., Pezzella, F. R., Corsi, F., Giorgianni, A., Baruzzi, F., Pellegrino, C., Terrana, A., Versino, M., Delodovici, M. L., Carimati, F., Cariddi, L. Princiotta, Auteri, W., Di Benedetto, O., Silvagni, U., Perrotta, P., Crispino, E., Petrone, A., Stancati, F., Rizzuto, S., Pugliese, P., Pisani, E., Siniscalchi, A., Gaudiano, C., Pirritano, D., Del Giudice, F., Piano, M., Agostoni, E., Motto, C., Gatti, A., Guccione, A., Tortorella, R., Stecco, A., Guzzardi, G., Del Sette, B., Coppo, L., Baldan, J., Romano, D., Siani, A., Locatelli, G., Saponiero, R., Napolitano, R., De Gregorio, M., Volpe, G., Tenuta, M., Guidetti, G., Biraschi, F., Wulbek, A., Falcou, A., Anzini, A., Mancini, A., De Michele, M., Fausti, S., Di Mascio, M. T., Durastanti, L., Sbardella, E., Mellina, V., Nicolini, E., Comelli, S., Ganau, C., Corraine, S., Fusaro, F., Ferrari, A., Schirru, F., Ledda, V., Secci, S., Melis, M., Piras, V., Moller, J., Padolecchia, R., Allegretti, L., Caldiera, V., Calia, S., Ganci, G., Tassinari, T., Sugo, A., De Nicola, M., Giannoni, M., Bruni, S., Gambelli, E., Provinciali, L., Nuzzi, N. P., Marcheselli, S., Corato, M., Scomazzoni, F., Simionato, F., Roveri, L., Filauri, P., Sacco, S., Orlandi, B., De Santis, F., Tiseo, C., Notturno, F., Ornello, R., Pavia, M., Squassina, G., Cobelli, M., Morassi, M., Magni, E., Invernizzi, P., Pepe, F., Bigni, B., Costa, P., Crabbio, M., Griffini, S., Palmerini, F., Piras, M. P., Gallesio, I., Barbero, S., Ferrandi, D., Dui, G., Fancello, M. C., Zedda, S., Ticca, A., Saddi, M. V., Deiana, G., Rossi, R., Carboni, N., Mela, A., Amistà, P., Russo, M., Iannucci, G., Pinna, V., Di Clemente, L., Santi, M., De Boni, A., De Luca, C., Natrella, M., Fanelli, G., Cristoferi, M., Bottacchi, E., Corso, G., Tosi, P., Sessa, M., Giossi, A., Baietti, Null, Romano, G., Meineri, P., Armentano, A., Versace, P., Arcudi, L., Galvano, G., Petralia, B., Feraco, P., Luppi, G., Giometto, B., Bignamini, V., Piffer, S., Meloni, G. B., Fabio, C., Maiore, M., Pintus, F., Pischedda, A., Manca, A., Mongili, C., Zanda, B., Baule, A., Florio, F., Ciccarese, G., Leone, M., Di Viesti, P., Pappalardo, M. P., Craparo, G., Gallo, C., Monaco, S., Mannino, M., Muto, M., Guarnieri, Gl., Andreone, V., Passalacqua, G., Allegritti, M., Caproni, S., Filizzolo, M., Salmaggi, A., Giordano, A., Marini, C., Frattale, I., Lucente, G., Nozzoli, C., and Lupo, F. A.
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Stent ,Acute stroke ,Settore MED/37 - Neuroradiologia ,Acute stroke Internal carotid artery diseases Stent Thrombectomy ,Neurology (clinical) ,General Medicine ,Settore MED/26 ,Internal carotid artery diseases ,Thrombectomy - Abstract
The management of tandem extracranial internal carotid artery and intracranial large vessel occlusion during endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) has been under-investigated. We sought to investigate outcomes of AIS patients with tandem occlusion (TO) treated with carotid artery stenting (CAS) compared to those not treated with CAS (no-CAS) during EVT.We performed a cohort study using data from AIS patients enrolled in the Italian Registry of Endovascular Treatment in Acute Stroke. Outcomes were 3 months' mortality, functional outcome, complete and successful recanalization, any intracranial hemorrhage, parenchymal hematoma and symptomatic intracerebral hemorrhage.Among 466 AIS patients with TO, CAS patients were 122 and no-CAS patients were 226 (118 excluded). After adjustment for unbalanced variables, CAS was associated with a lower rate of 3 months' mortality (OR 0.407, 95% CI 0.171-0.969, p = 0.042). After adjustment for pre-defined variables, CAS was associated with a lower rate of 3 months' mortality (aOR 0.430, 95% CI 0.187-0.989, p = 0.047) and a higher rate of complete recanalization (aOR 1.986, 95% CI 1.121-3.518, p = 0.019), successful recanalization (aOR 2.433, 95% CI 1.263-4.686, p = 0.008) and parenchymal hematoma (aOR 2.876, 95% CI 1.173-7.050, p = 0.021). CAS was associated with lower 3 months mortality (OR 0.373, 95% CI 0.141-0.982, p = 0.046) and higher rates of successful recanalization (OR 2.082, 95% CI 1.099-3.942, p = 0.024) after adjustment for variables associated with 3 months' mortality and successful recanalization, respectively.Among AIS patients with TO, CAS during EVT was associated with a higher rate of successful reperfusion and a lower rate of 3 months' mortality.
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- 2022
43. Investigation of the low energy kaons hadronic interactions in light nuclei by AMADEUS
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Piscicchia, K., Bazzi, M., Berucci, C., Bosnar, D., Bragadireanu, A. M., Cargnelli, M., Clozza, A., Curceanu, C., Grande, R. Del, D’uffizi, A., Fabbietti, L., Fiorini, C., Ghio, F., Guaraldo, C., Iliescu, M., Sandri, P. Levi, Marton, J., Moskal, P., Pietreanu, D., Lener, M. Poli, Quaglia, R., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Skurzok, M., Silarski, M., Sirghi, D., Sirghi, F., Tucakovic, I., Doce, O. Vazquez, Widmann, E., and Zmeskal, J.
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- 2015
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- View/download PDF
44. Neuroimaging evidence of gray and white matter damage and clinical correlates in progressive supranuclear palsy
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Piattella, Maria Cristina, Upadhyay, N., Bologna, M., Sbardella, E., Tona, F., Formica, A., Petsas, N., Berardelli, A., and Pantano, P.
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- 2015
- Full Text
- View/download PDF
45. Effect of risedronate in osteoporotic HIV males, according to gonadal status: a pilot study
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Pepe, J., Isidori, A. M., Falciano, M., Iaiani, G., Salotti, A., Diacinti, D., Del Fiacco, R., Sbardella, E., Cipriani, C., Piemonte, S., Raimo, O., Biondi, P., Biamonte, F., Lenzi, A., and Minisola, S.
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- 2014
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46. L-series X-ray yields of kaonic 3He and 4He atoms in gaseous targets
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Bazzi, M., Beer, G., Berucci, C., Bragadireanu, A. M., Cargnelli, M., Curceanu, C., d’Uffizi, A., Fiorini, C., Ghio, F., Guaraldo, C., Hayano, R. S., Iliescu, M., Ishiwatari, T., Iwasaki, M., Sandri, P. Levi, Marton, J., Okada, S., Pietreanu, D., Ponta, T., Quaglia, R., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Vazquez Doce, O., Wünschek, B., Widmann, E., Zmeskal, J., and The SIDDHARTA Collaboration
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- 2014
- Full Text
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47. VIP 2: experimental tests of the pauli exclusion principle for electrons
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Pichler, A., primary, Bartalucci, S., additional, Bertolucci, S., additional, Berucci, C., additional, Bragadireanu, M., additional, Cargnelli, M., additional, Clozza, A., additional, Curceanu, C., additional, De Paolis, L., additional, Di Matteo, S., additional, D’Uffizi, A., additional, Egger, J.-P., additional, Guaraldo, C., additional, Iliescu, M., additional, Ishiwatari, T., additional, Laubenstein, M., additional, Marton, J., additional, Milotti, E., additional, Pietreanu, D., additional, Piscicchia, K., additional, Ponta, T., additional, Sbardella, E., additional, Scordo, A., additional, Shi, H., additional, Sirghi, D., additional, Sirghi, F., additional, Sperandio, L., additional, Vazquez-Doce, O., additional, Widmann, E., additional, and Zmeskal, J., additional
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- 2015
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- View/download PDF
48. Epidemiology of pancreatic neuroendocrine neoplasms. a gender perspective
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Muscogiuri, G., Altieri, B., Albertelli, M., Dotto, A., Modica, R., Barrea, L., Fanciulli, G., Feola, T., Baldelli, R., Ruggeri, R. M., Gallo, M., Guarnotta, V., Malandrino, P., Messina, E., Venneri, M. A., Giannetta, E., Ferone, D., Colao, A., Faggiano, A., Bottiglieri, F., Campione, S., de Cicco, F., Dicitore, A., Ferrau, F., Grillo, F., Grossrubatscher, E., Guadagno, E., Isidori, A. M., Lania, A., Lenzi, A., Calzo, F. L., Pes, L., Pizza, G., Pofi, R., Puliani, G., Rainone, C., Razzore, P., Rizza, L., Rubino, M., Sbardella, E., Sesti, F., Vitale, G., Zatelli, M. C., Muscogiuri G, Altieri B, Albertelli M, Dotto A, Modica R, Barrea L, Fanciulli G, Feola T, Baldelli R, Ruggeri RM, Gallo M, Guarnotta V, Malandrino P, Messina E, Venneri MA, Giannetta E, Ferone D, Colao A, Faggiano A, Muscogiuri, G., Altieri, B., Albertelli, M., Dotto, A., Modica, R., Barrea, L., Fanciulli, G., Feola, T., Baldelli, R., Ruggeri, R. M., Gallo, M., Guarnotta, V., Malandrino, P., Messina, E., Venneri, M. A., Giannetta, E., Ferone, D., Colao, A., Faggiano, A., Bottiglieri, F., Campione, S., de Cicco, F., Dicitore, A., Ferrau, F., Grillo, F., Grossrubatscher, E., Guadagno, E., Isidori, A. M., Lania, A., Lenzi, A., Calzo, F. L., Pes, L., Pizza, G., Pofi, R., Puliani, G., Rainone, C., Razzore, P., Rizza, L., Rubino, M., Sbardella, E., Sesti, F., Vitale, G., and Zatelli, M. C.
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Male ,medicine.medical_specialty ,Cardiovascular diseases ,Epidemiology ,Gender ,Pancreatic neuroendocrine neoplasms ,Sex ,Type 2 diabetes ,Female ,Humans ,Middle Aged ,Pancreas ,Retrospective Studies ,Diabetes Mellitus, Type 2 ,Neuroendocrine Tumors ,Pancreatic Neoplasms ,Pancreatic neuroendocrine neoplasm ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,Disease ,Neuroendocrine tumors ,Type 2 diabete ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Retrospective Studie ,Internal medicine ,Diabetes mellitus ,medicine ,gender ,Pancrea ,sex ,business.industry ,pancreatic neuroendocrine neoplasms ,Retrospective cohort study ,medicine.disease ,Cardiovascular disease ,cardiovascular diseases ,Natural history ,030220 oncology & carcinogenesis ,Pancreatitis ,epidemiology ,type 2 diabetes ,business ,Neuroendocrine Tumor ,Human - Abstract
Purpose: Pancreatic neuroendocrine neoplasms (PNENs) are a group of clinically rare and heterogeneous tumors of the pancreas. Currently there are no studies investigating the gender difference in PNEN susceptibility. Thus, the purpose of this study was aimed at examining how gender shapes risk factors, clinicopathological features, and comorbidities in PNENs. Methods: The study design consisted of an Italian multicenter, retrospective study. The study included all consecutive patients with PNENs followed at the participating centers. Two hundred and twenty-nine patients (105 males,124 females, age 54 ± 0.98 years) with PNENs were enrolled at the participating centers. The clinicopathological features (age, gender, BMI, histology, tumor size, tumor grade, distant metastasis, hormonal function, and diagnostic circumstances), comorbidities (cardiovascular diseases (CVD), pancreatitis, type 2 diabetes (T2DM), and potential risk factors (smoking and drinking) were included in the analysis. Results: Females were slightly prevalent (54.15%). PNENs were diagnosed at younger age in females compared to males (p = 0.04). The prevalence of CVD was significantly higher in males than in females (p = 0.006). In the female group, the presence of T2DM was significantly associated with higher tumor grade (p = 0.04) and metastatic disease (p = 0.02). The proportion of smokers and alcohol drinkers was significantly higher in the male group (p < 0.001). No significant gender differences were detected regarding the other parameters included in the analysis. Conclusions: This study has identified gender differences of PNENs in terms of age at diagnosis, associated comorbidities, and potential risk factors. A gender-tailored approach could become a potential strategy to better understand the natural history of PNENs and improve the effectiveness of PNENs clinical management.
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- 2020
49. Emerging Therapies in Pheochromocytoma and Paraganglioma: Immune Checkpoint Inhibitors in the Starting Blocks
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Fanciulli G., Di Molfetta S., Dotto A., Florio T., Feola T., Rubino M., de Cicco F., Colao A., Faggiano A., Albertelli M., Altieri B., Barrea L., Bottiglieri F., Campione S., Dicitore A., Ferone D., Ferrau F., Grossrubatscher E., Gallo M., Giannetta E., Grillo F., Guadagno E., Guarnotta V., Isidori A. M., Lania A., Lenzi A., Lo Calzo F., Malandrino P., Messina E., Modica R., Muscogiuri G., Pizza G., Pes L., Pofi R., Puliani G., Rainone C., Razzore P., Rizza L., Ruggieri R. M., Sbardella E., Sesti F., Venneri M. A., Vitale G., Zatelli M. C., Fanciulli G., Di Molfetta S., Dotto A., Florio T., Feola T., Rubino M., de Cicco F., Colao A., Faggiano A., Albertelli M., Altieri B., Barrea L., Bottiglieri F., Campione S., Dicitore A., Ferone D., Ferrau F., Grossrubatscher E., Gallo M., Giannetta E., Grillo F., Guadagno E., Guarnotta V., Isidori A.M., Lania A., Lenzi A., Lo Calzo F., Malandrino P., Messina E., Modica R., Muscogiuri G., Pizza G., Pes L., Pofi R., Puliani G., Rainone C., Razzore P., Rizza L., Ruggieri R.M., Sbardella E., Sesti F., Venneri M.A., Vitale G., Zatelli M.C., Fanciulli, G., Di Molfetta, S., Dotto, A., Florio, T., Feola, T., Rubino, M., de Cicco, F., Colao, A., Faggiano, A., Albertelli, M., Altieri, B., Barrea, L., Bottiglieri, F., Campione, S., Dicitore, A., Ferone, D., Ferrau, F., Grossrubatscher, E., Gallo, M., Giannetta, E., Grillo, F., Guadagno, E., Guarnotta, V., Isidori, A. M., Lania, A., Lenzi, A., Lo Calzo, F., Malandrino, P., Messina, E., Modica, R., Muscogiuri, G., Pizza, G., Pes, L., Pofi, R., Puliani, G., Rainone, C., Razzore, P., Rizza, L., Ruggieri, R. M., Sbardella, E., Sesti, F., Venneri, M. A., Vitale, G., and Zatelli, M. C.
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atezolizumab ,avelumab ,cemiplimab ,durvalumab ,immune checkpoint inhibitors ,ipilimumab ,nivolumab ,paraganglioma ,pembrolizumab ,pheochromocytoma ,lcsh:Medicine ,Ipilimumab ,Review ,Immune checkpoint inhibitor ,Pembrolizumab ,Bioinformatics ,Pheochromocytoma ,Avelumab ,03 medical and health sciences ,0302 clinical medicine ,Paraganglioma ,Atezolizumab ,Medicine ,Ate-zolizumab ,030304 developmental biology ,0303 health sciences ,business.industry ,lcsh:R ,General Medicine ,medicine.disease ,Clinical trial ,030220 oncology & carcinogenesis ,Nivolumab ,business ,medicine.drug - Abstract
Pheochromocytoma and paraganglioma are neuroendocrine neoplasms, originating in the adrenal medulla and in parasympathetic and sympathetic autonomic nervous system ganglia, respectively. They usually present as localized tumours curable with surgery. However, these tumours may exhibit heterogeneous clinical course, ranging from no/minimal progression to aggressive (progressive/metastatic) behavior. For this setting of patients, current therapies are unsatisfactory. Immune checkpoint inhibitors have shown outstanding results for several types of solid cancers. We therefore aimed to summarize and discuss available data on efficacy and safety of current FDA-approved immune checkpoint inhibitors in patients with pheochromocytoma and paraganglioma. After an extensive search, we found 15 useful data sources (four full-published articles, four supplements of scientific journals, seven ongoing registered clinical trials). The data we detected, even with the limit of the small number of patients treated, make a great expectation on the therapeutic use of immune checkpoint inhibitors. Besides, the newly detected predictors of response will (hopefully) be of great helps in selecting the subset of patients that might benefit the most from this class of drugs. Finally, new trials are in the starting blocks, and they are expected to shed in the next future new light on a therapy, which is considered a milestone in oncology.
- Published
- 2020
50. Kaon-Nucleon Strong Interaction in Kaonic Atoms: The SIDDHARTA Program
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Iliescu, M., Bazzi, M., Beer, G., Bombelli, L., Bragadireanu, A. M., Cargnelli, M., Curceanu (Petrascu), C., d’Uffizi, A., Fiorini, C., Frizzi, T., Ghio, F., Guaraldo, C., Hayano, R. S., Ishiwatari, T., Iwasaki, M., Kienle, P., Levi Sandri, P., Longoni, A., Marton, J., Okada, S., Pietreanu, D., Ponta, T., Rizzo, A., Romero Vidal, A., Sbardella, E., Scordo, A., Shi, H., Sirghi, D. L., Sirghi, F., Tatsuno, H., Tudorache, A., Tudorache, V., Vazquez Doce, O., Widmann, E., Wünschek, B., and Zmeskal (SIDDHARTA Collaboration), J.
- Published
- 2013
- Full Text
- View/download PDF
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