41 results on '"Saxton, D"'
Search Results
2. Three-dimensional single-molecule super-resolution imaging of proteins involved in primary cilia formation
- Author
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Love, Julia F., primary, Fisher, Saxton D., additional, Tomoharu, Kanie, additional, Gustavsson, Anna-Karin, additional, and Jackson, Peter K., additional
- Published
- 2023
- Full Text
- View/download PDF
3. A hierarchical pathway for assembly of the distal appendages that organize primary cilia
- Author
-
Kanie, Tomoharu, primary, Love, Julia F., additional, Fisher, Saxton D., additional, Gustavsson, Anna-Karin, additional, and Jackson, Peter K., additional
- Published
- 2023
- Full Text
- View/download PDF
4. A hierarchical pathway for assembly of the distal appendages that organize primary cilia
- Author
-
Tomoharu Kanie, Julia F. Love, Saxton D. Fisher, Anna-Karin Gustavsson, and Peter K. Jackson
- Abstract
SummaryDistal appendages are nine-fold symmetric blade-like structures attached to the distal end of the mother centriole. These structures are critical for formation of the primary cilium, by regulating at least four critical steps: ciliary vesicle recruitment, recruitment and initiation of intraflagellar transport (IFT), and removal of CP110. While specific proteins that localize to the distal appendages have been identified, how exactly each protein functions to achieve the multiple roles of the distal appendages is poorly understood. Here we comprehensively analyze known and newly discovered distal appendage proteins (CEP83, SCLT1, CEP164, TTBK2, FBF1, CEP89, KIZ, ANKRD26, PIDD1, LRRC45, NCS1, C3ORF14) for their precise localization, order of recruitment, and their roles in each step of cilia formation. Using CRISPR-Cas9 knockouts, we show that the order of the recruitment of the distal appendage proteins is highly interconnected and a more complex hierarchy. Our analysis highlights two protein modules, CEP83-SCLT1 and CEP164-TTBK2, as critical for structural assembly of distal appendages. Functional assay revealed that CEP89 selectively functions in RAB34+ciliary vesicle recruitment, while deletion of the integral components, CEP83-SCLT1-CEP164-TTBK2, severely compromised all four steps of cilium formation. Collectively, our analyses provide a more comprehensive view of the organization and the function of the distal appendage, paving the way for molecular understanding of ciliary assembly.
- Published
- 2023
5. Three-dimensional single-molecule super-resolution imaging of proteins involved in primary cilia formation
- Author
-
Julia F. Love, Saxton D. Fisher, Kanie Tomoharu, Anna-Karin Gustavsson, and Peter K. Jackson
- Subjects
Biophysics - Published
- 2023
6. Modeling Use Diffusion
- Author
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Hamblin, Robert L. and Saxton, D. Eugene
- Published
- 1979
- Full Text
- View/download PDF
7. Australia's awareness of cardiac arrest and rates of CPR training: Results from the Heart Foundation's HeartWatch survey
- Author
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Cartledge, S, Saxton, D, Finn, J, Bray, JE, Cartledge, S, Saxton, D, Finn, J, and Bray, JE
- Abstract
Objective: We aimed to provide the first national estimates of cardiopulmonary resuscitation (CPR) training and awareness of cardiac arrest. Design: A retrospective analysis of a national cross-sectional survey was undertaken. Data were collected online from adults in July 2017 as part of the Heart Foundation of Australia’s HeartWatch survey. We used logistic regression to examine demographic factors associated with CPR training. Participants: A national cohort was invited to participate in the survey using purposive, non-probability sampling methods with quotas for age, gender and area of residence, in order to reflect the wider Australian population. The final sample consisted of 1076 respondents. Main outcome measure: To determine an estimation of the prevalence of cardiac arrest awareness and CPR training at a national level and the relationship of training to demographic factors. Results: The majority (76%) of respondents were born in Australia with 51% female and 66% aged between 35 and 64 years. Only 16% of respondents could identify the difference between a cardiac arrest and a heart attack. While 56% reported previous CPR training, only 22% were currently trained (within 1 year). CPR training was associated with younger age (35 to 54 years) (OR 1.45, 95% CI 1.06 to 2.0), being born in Australia (OR 1.59, 95% CI 1.17 to 2.17) and higher levels of education (university, OR 1.86, 95% CI 1.35 to 2.57). CPR training increased confidence in respondents ability to perform effective CPR and use a defibrillator. Lack of CPR training was the most common reason why respondents would not provide CPR to a stranger. Conclusions: There is a need to improve the community’s understanding of cardiac arrest, and to increase awareness and training in CPR. CPR training rates have not changed over the past decades—new initiatives are needed.
- Published
- 2020
8. Australia's awareness of cardiac arrest and rates of CPR training: Results from the Heart Foundation's HeartWatch survey
- Author
-
Cartledge, S., Saxton, D., Finn, Judith, Bray, Janet, Cartledge, S., Saxton, D., Finn, Judith, and Bray, Janet
- Abstract
Objective: We aimed to provide the first national estimates of cardiopulmonary resuscitation (CPR) training and awareness of cardiac arrest. Design: A retrospective analysis of a national cross-sectional survey was undertaken. Data were collected online from adults in July 2017 as part of the Heart Foundation of Australia's HeartWatch survey. We used logistic regression to examine demographic factors associated with CPR training. Participants: A national cohort was invited to participate in the survey using purposive, non-probability sampling methods with quotas for age, gender and area of residence, in order to reflect the wider Australian population. The final sample consisted of 1076 respondents. Main outcome measure: To determine an estimation of the prevalence of cardiac arrest awareness and CPR training at a national level and the relationship of training to demographic factors. Results: The majority (76%) of respondents were born in Australia with 51% female and 66% aged between 35 and 64 years. Only 16% of respondents could identify the difference between a cardiac arrest and a heart attack. While 56% reported previous CPR training, only 22% were currently trained (within 1 year). CPR training was associated with younger age (35 to 54 years) (OR 1.45, 95% CI 1.06 to 2.0), being born in Australia (OR 1.59, 95% CI 1.17 to 2.17) and higher levels of education (university, OR 1.86, 95% CI 1.35 to 2.57). CPR training increased confidence in respondents ability to perform effective CPR and use a defibrillator. Lack of CPR training was the most common reason why respondents would not provide CPR to a stranger. Conclusions: There is a need to improve the community's understanding of cardiac arrest, and to increase awareness and training in CPR. CPR training rates have not changed over the past decades - new initiatives are needed.
- Published
- 2020
9. LETTERS
- Author
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Uzman, Akif, Byrd, Tim, Saxton, D., Weller, Mark, Javed, Nasser, Haywood, Nancy, Moore, Tom, Strahan, D.W., Gold, Robert, and Martin, Buster
- Subjects
General interest ,News, opinion and commentary - Published
- 2008
10. LETTERS
- Author
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Keane, Kevin, Hendricks, Thomas R., Debrovner, Linda, Braastad, Richard, Saxton, D., Reed, Ken, and Stringer, Barbara
- Subjects
General interest ,News, opinion and commentary - Published
- 2007
11. LETTERS
- Author
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Saxton, D., Hudman, Lee, Vyas, Malay, Herrada, Pete, Auzenne, Murvin R., Weesner, Mark, and Smith, Sarah
- Subjects
General interest ,News, opinion and commentary - Published
- 2006
12. POSTER VIEWING SESSION - ANDROLOGY
- Author
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Dul, E. C., primary, van Ravenswaaij-Arts, C. M. A., additional, Groen, H., additional, van Echten-Arends, J., additional, Land, J. A., additional, Tyulenev, Y., additional, Naumenko, V., additional, Kurilo, L., additional, Shileiko, L., additional, Segal, A., additional, Klimova, R., additional, Kushch, A., additional, Ribas-Maynou, J., additional, Garcia-Peiro, A., additional, Abad, C., additional, Amengual, M. J., additional, Benet, J., additional, Navarro, J., additional, Colasante, A., additional, Lobascio, A. M., additional, Scarselli, F., additional, Minasi, M. G., additional, Alviggi, E., additional, Rubino, P., additional, Casciani, V., additional, Pena, R., additional, Varricchio, M. T., additional, Litwicka, K., additional, Ferrero, S., additional, Zavaglia, D., additional, Franco, G., additional, Nagy, Z. P., additional, Greco, E., additional, Romany, L., additional, Meseguer, M., additional, Garcia-Herrero, S., additional, Pellicer, A., additional, Garrido, N., additional, Dam, A., additional, Pijnenburg, A., additional, Hendriks, J. C., additional, Westphal, J. R., additional, Ramos, L., additional, Kremer, J. A. M., additional, Eertmans, F., additional, Bogaert, V., additional, Puype, B., additional, Geisler, W., additional, Clusmann, C., additional, Klopsch, I., additional, Strowitzki, T., additional, Eggert-Kruse, W., additional, Maettner, R., additional, Isachenko, E., additional, Isachenko, V., additional, Strehler, E., additional, Sterzik, K., additional, Band, G., additional, Madgar, I., additional, Brietbart, H., additional, Naor, Z., additional, Cunha-Filho, J. S., additional, Souza, C. A., additional, Krebs, V. G., additional, Santos, K. D., additional, Koff, W. J., additional, Stein, A., additional, Hammoud, I., additional, Albert, M., additional, Bergere, M., additional, Bailly, M., additional, Boitrelle, F., additional, Vialard, F., additional, Wainer, R., additional, Izard, V., additional, Selva, J., additional, Cohen - Bacrie, P., additional, Belloc, S., additional, de mouzon, J., additional, Cohen-Bacrie, M., additional, Alvarez, S., additional, Junca, A. M., additional, Dumont, M., additional, Douard, S., additional, Prisant, N., additional, Tomita, K., additional, Hashimoto, S., additional, Akamatsu, Y., additional, Satoh, M., additional, Mori, R., additional, Inoue, T., additional, Ohnishi, Y., additional, Ito, K., additional, Nakaoka, Y., additional, Morimoto, Y., additional, Smith, V. J. H., additional, Ahuja, K. K., additional, Atig, F., additional, Raffa, M., additional, Sfar, M. T., additional, Saad, A., additional, Ajina, M., additional, Braga, D. P. A. F., additional, Halpern, G., additional, Figueira, R. C. S., additional, Setti, A. S., additional, Iaconelli Jr., A., additional, Borges Jr., E., additional, Medeiros, G. S., additional, Pasqualotto, E. B., additional, Pasqualotto, F. F., additional, Nadalini, M., additional, Tarozzi, N., additional, Di Santo, M., additional, Borini, A., additional, Lopez-Fernandez, C., additional, Arroyo, F., additional, Caballero, P., additional, Nunez-Calonge, R., additional, Fernandez, J. L., additional, Gosalvez, J., additional, Gosalbez, A., additional, Cortes, S., additional, Zikopoulos, K., additional, Lazaros, L., additional, Vartholomatos, G., additional, Kaponis, A., additional, Makrydimas, G., additional, Plachouras, N., additional, Sofikitis, N., additional, Kalantaridou, S., additional, Hatzi, E., additional, Georgiou, I., additional, de Mouzon, J., additional, Amar, E., additional, Cohen-Bacrie, P., additional, Vuillaume, M. L., additional, Brugnon, F., additional, Artonne, C., additional, Janny, L., additional, Pons-Rejraji, H., additional, Fedder, J., additional, Bosco, L., additional, Ruvolo, G., additional, Bruccoleri, A. M., additional, Manno, M., additional, Roccheri, M. C., additional, Cittadini, E., additional, Bochev, I., additional, Gavrilov, P., additional, Kyurkchiev, S., additional, Shterev, A., additional, Carlomagno, G., additional, Colone, M., additional, Condorelli, R. A., additional, Stringaro, A., additional, Calogero, A. E., additional, Zakova, J., additional, Kralikova, M., additional, Crha, I., additional, Ventruba, P., additional, Melounova, J., additional, Matejovicova, M., additional, Vodova, M., additional, Lousova, E., additional, Sanchez Toledo, M., additional, Alvarez LLeo, C., additional, Garcia Garrido, C., additional, Resta Serra, M., additional, Belmonte Andujar, L. L., additional, Gonzalez de Merlo, G., additional, Pohanka, M., additional, Huser, M., additional, Amiri, I., additional, Karimi, J., additional, Goodarzi, M. T., additional, Tavilani, H., additional, Filannino, A., additional, Magli, M. C., additional, Boudjema, E., additional, Crippa, A., additional, Ferraretti, A. P., additional, Gianaroli, L., additional, Robles, F., additional, Huang, H., additional, Yao, D. J., additional, Huang, H. J., additional, Li, J. R., additional, Fan, S. K., additional, Wang, M. L., additional, Yung-Kuei, S., additional, Amer, S., additional, Mahran, A., additional, Darne, J., additional, Shaw, R., additional, Borghi, E., additional, Cetera, C., additional, Shukla, U., additional, Ogutu, D., additional, Deval, B., additional, Jansa, M., additional, Savvas, M., additional, Narvekar, N., additional, Houska, P., additional, Dackland, A. L., additional, Bjorndahl, L., additional, Kvist, U., additional, Muzii, L., additional, Barboni, B., additional, Samanta, L., additional, Kar, S., additional, Yakovenko, S. A., additional, Troshina, M. N., additional, Rutman, B. K., additional, Dyakonov, S. A., additional, Holmes, E., additional, Feijo, C., additional, Verza Junior, S., additional, Esteves, S. C., additional, Berta, C. L., additional, Caille, A. M., additional, Ghersevich, S. A., additional, Zumoffen, C., additional, Munuce, M. J., additional, San Celestino, M., additional, Agudo, D., additional, Alonso, M., additional, Sanjurjo, P., additional, Becerra, D., additional, Bronet, F., additional, Garcia-Velasco, J. A., additional, Pacheco, A., additional, Lafuente, R., additional, Lopez, G., additional, Checa, M. A., additional, Carreras, R., additional, Brassesco, M., additional, Oneta, M., additional, Savasi, V., additional, Parrilla, B., additional, Guarneri, D., additional, Laureti, A., additional, Pagano, F., additional, Cetin, I., additional, Ekwurtzel, E., additional, Morgante, G., additional, Piomboni, P., additional, Stendardi, A., additional, Serafini, F., additional, De Leo, V., additional, Focarelli, R., additional, Benkhalifa, M., additional, De Mouzon, J., additional, Entezami, F., additional, Junca, A., additional, De Mouzon, J. J., additional, Mangiarini, A., additional, Capitanio, E., additional, Paffoni, A., additional, Restelli, L., additional, Guarneri, C., additional, Scarduelli, C., additional, Ragni, G., additional, Harrison, K., additional, Irving, J., additional, Martin, N., additional, Sherrin, D., additional, Yazdani, A., additional, Almeida, C., additional, Correia, S., additional, Rocha, E., additional, Alves, A., additional, Cunha, M., additional, Ferraz, L., additional, Silva, S., additional, Sousa, M., additional, Barros, A., additional, Perdrix, A., additional, Travers, A., additional, Milazzo, J. P., additional, Clatot, F., additional, Mousset-Simeon, N., additional, Mace, B., additional, Rives, N., additional, Clarke, H. S., additional, Callow, A., additional, Saxton, D., additional, Pacey, A. A., additional, Sapir, O., additional, Oron, G., additional, Ben-Haroush, A., additional, Garor, R., additional, Feldberg, D., additional, Pinkas, H., additional, Wertheimer, A., additional, Fisch, B., additional, Palacios, E., additional, Gonzalvo, M. C., additional, Clavero, A., additional, Ramirez, J. P., additional, Rosales, A., additional, Mozas, J., additional, Castilla, J. A., additional, Mugica, J., additional, Ramon, O., additional, Valdivia, A., additional, Exposito, A., additional, Casis, L., additional, Matorras, R., additional, Bongers, R., additional, Gottardo, F., additional, Zitzmann, M., additional, Kliesch, S., additional, Cordes, T., additional, Kamischke, A., additional, Schultze-Mosgau, A., additional, Buendgen, N., additional, Diedrich, K., additional, Griesinger, G., additional, Crisol, L., additional, Aspichueta, F., additional, Hernandez, M. L., additional, Ruiz-Sanz, J. I., additional, Mendoza, R., additional, Sanchez-Tusie, A. A., additional, Bermudez, A., additional, Lopez, P., additional, Churchill, G. C., additional, Trevino, C. L., additional, Maldonado, I., additional, and Dabbah, J., additional
- Published
- 2011
- Full Text
- View/download PDF
13. Orbital transfer vehicle - An overview
- Author
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Caluori, V. A and Saxton, D. R
- Subjects
Launch Vehicles And Space Vehicles - Abstract
A summary is given of the concept definition phase of NASA's Orbital Transfer Vehicle (OTV) program. The mission requirements are threefold: (1) the ability to deliver payloads well beyond the capability of any current system at low acceleration levels, (2) the extension of the cost effectiveness from reusability and operational flexibility provided by the Shuttle at LEO to the geosynchronous altitude, and (3) the provision of the round trip capability needed to service and maintain this expanded and more valuable resource at GEO. The initial Shuttle-matched, reusable OTV is shown to be cost effective with low development cost, relatively short development period and high projected reliability. The performance enhancement provided by aero-assist is discussed, which will enable the difficult round trip to be flown in a single Shuttle launch. Two methods of reducing vehicle velocity are available: (1) aeromaneuvering, which uses vehicle lift to climb or descend and thereby correct for density variations, and (2) aerobraking which varies vehicle drag directly to correct for density.
- Published
- 1981
14. Early space station user accommodations
- Author
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Saxton, D. R and Wolbers, H. L
- Subjects
Spacecraft Design, Testing And Performance - Abstract
The requirements for extended-duration space missions in earth orbit beyond those anticipated for the 7- to 30-day Shuttle Spacelab system have been examined. It has been determined that a continuously manned, free-flying orbital facility provides a realistic and cost-effective space platform for multidiscipline payloads designed to support research, applications, and system implementation programs such as the assembly of large space structures, and on-orbit space manufacturing. A conceptual description of such a manned facility (early Space Station) and the accommodations that it can provide using agencies and organizations is presented in this paper.
- Published
- 1975
15. Findings of the system implementation and operations peer group
- Author
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Ingram, D, Schlumberger, J. Q, Johannsen, C, Dragg, J. L, Degloria, S, Saxton, D, Sos, J, and Wall, S
- Subjects
Earth Resources And Remote Sensing - Abstract
There are no author-identified significant results in this report.
- Published
- 1978
16. Toward modular nuclear-rocket systems.
- Author
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Harris, D. J, Jordan, W. Y., Jr, and Saxton, D. R
- Subjects
Nuclear Engineering - Abstract
Propulsion module consisting of Nerva-2-class engine and Saturn V stage would permit wide spectrum of space missions including near-Earth, cislunar and manned interplanetary flight
- Published
- 1965
17. CREEP OF URANIUM
- Author
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Saxton, D, primary and Murphy, G, additional
- Published
- 1958
- Full Text
- View/download PDF
18. Implementation of the RELP vocoder using the TMS320.
- Author
-
Dankberg, M., Iltis, R., Saxton, D., and Wilson, P.
- Published
- 1984
- Full Text
- View/download PDF
19. Nitrogen reflow ovens: the effect exit temperature has on benzotriazole coated copper boards.
- Author
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Gutierrez, S., Saxton, D., Schluter, R., and Thune, P.
- Published
- 1995
- Full Text
- View/download PDF
20. Accuracy of ultrasound measurements of female pelvic organs
- Author
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SAXTON, D. W., primary, FARQUHAR, C. M., additional, RAE, T., additional, BEARD, R. W., additional, ANDERSON, M. C., additional, and WADSWORTH, J., additional
- Published
- 1990
- Full Text
- View/download PDF
21. Design and performance of a programmable real-time charge-coupled-device recirculating delay-line correlator.
- Author
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Mavor, J., Jack, M.A., Saxton, D., and Grant, P.M.
- Published
- 1977
- Full Text
- View/download PDF
22. The behaviour of infants whose mothers smoke in pregnancy
- Author
-
Saxton, D
- Published
- 1978
- Full Text
- View/download PDF
23. The nature and causes of clear-air turbulence
- Author
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SAXTON, D., primary
- Published
- 1966
- Full Text
- View/download PDF
24. Implementation of the RELP vocoder using the TMS320
- Author
-
Dankberg, M., primary, Iltis, R., additional, Saxton, D., additional, and Wilson, P., additional
- Full Text
- View/download PDF
25. Nitrogen reflow ovens: the effect exit temperature has on benzotriazole coated copper boards
- Author
-
Gutierrez, S., primary, Saxton, D., additional, Schluter, R., additional, and Thune, P., additional
- Full Text
- View/download PDF
26. TOWARD MODULAR NUCLEAR-ROCKET SYSTEMS
- Author
-
Saxton, D
- Published
- 1965
27. A hierarchical pathway for assembly of the distal appendages that organize primary cilia.
- Author
-
Kanie T, Love JF, Fisher SD, Gustavsson AK, and Jackson PK
- Abstract
Distal appendages are nine-fold symmetric blade-like structures attached to the distal end of the mother centriole. These structures are critical for formation of the primary cilium, by regulating at least four critical steps: ciliary vesicle recruitment, recruitment and initiation of intraflagellar transport (IFT), and removal of CP110. While specific proteins that localize to the distal appendages have been identified, how exactly each protein functions to achieve the multiple roles of the distal appendages is poorly understood. Here we comprehensively analyze known and newly discovered distal appendage proteins (CEP83, SCLT1, CEP164, TTBK2, FBF1, CEP89, KIZ, ANKRD26, PIDD1, LRRC45, NCS1, C3ORF14) for their precise localization, order of recruitment, and their roles in each step of cilia formation. Using CRISPR-Cas9 knockouts, we show that the order of the recruitment of the distal appendage proteins is highly interconnected and a more complex hierarchy. Our analysis highlights two protein modules, CEP83-SCLT1 and CEP164-TTBK2, as critical for structural assembly of distal appendages. Functional assay revealed that CEP89 selectively functions in RAB34
+ ciliary vesicle recruitment, while deletion of the integral components, CEP83-SCLT1-CEP164-TTBK2, severely compromised all four steps of cilium formation. Collectively, our analyses provide a more comprehensive view of the organization and the function of the distal appendage, paving the way for molecular understanding of ciliary assembly.- Published
- 2023
- Full Text
- View/download PDF
28. It takes a community to save a life in cardiac arrest: Heart safe community pilots, Australia.
- Author
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Naccarella L, Saxton D, Lugg E, and Marley J
- Subjects
- Defibrillators, Humans, Victoria, Cardiopulmonary Resuscitation, Emergency Medical Services, Out-of-Hospital Cardiac Arrest therapy
- Abstract
Issue Addressed: In Australia only 1 in 12 people will survive an out of hospital cardiac arrest (OHCA). Heart Safe Community (HSC) is a public health initiative being implemented by the Heart Foundation, Victoria in partnership with Ambulance Victoria. It aims to improve survival from OHCA by improving public access to 24 hours Automated External Defibrillators (AEDs) and by building local community skills and confidence in basic resuscitation. Over the period 2017-20, the University of Melbourne was commissioned to evaluate the implementation, effectiveness, and sustainability of three HSC pilots in Victoria, Australia., Methods: Mixed methods were used including eight focus group discussions with 64 local HSC community stakeholders and local HSC pilot site evaluation data., Results: The local HSC pilot community presentation surveys revealed that the HSC pilots delivered hundreds of presentations on bystander resuscitation, with 2772 local community members being exposed to the call to action: 'Call, Push Shock' and 'anyone can save a life'. Focus group discussions revealed that the HSC pilots built local community capacity to respond to OHCA as demonstrated by increased knowledge, confidence and skills to call Emergency Medical Services, attempt chest compression, acquire and use an AED. Community leadership to advocate for improved access to AEDs and to propagate HSC initiatives amongst community settings and cohorts has occurred. HSC implementation enablers and challenges exist. Community capacity-building frameworks can explain what makes the HSC pilot work., Conclusion: HSC can build local community capacity to respond to OHCA. Eight principles are suggested to support the building, implementation and sustainability of future HSC efforts. SO WHAT?: The HSC experience reveals that community members across the lifespan and multiple settings embrace opportunities to improve the safety and response in their community to a cardiac arrest when the action is simplified and community ownership cultivated., (© 2021 Australian Health Promotion Association.)
- Published
- 2022
- Full Text
- View/download PDF
29. Australia's awareness of cardiac arrest and rates of CPR training: results from the Heart Foundation's HeartWatch survey.
- Author
-
Cartledge S, Saxton D, Finn J, and Bray JE
- Subjects
- Adolescent, Adult, Aged, Australia, Cross-Sectional Studies, Educational Status, Female, Humans, Male, Middle Aged, Retrospective Studies, Young Adult, Cardiology, Cardiopulmonary Resuscitation education, Health Education methods, Health Knowledge, Attitudes, Practice, Out-of-Hospital Cardiac Arrest therapy, Societies, Medical
- Abstract
Objective: We aimed to provide the first national estimates of cardiopulmonary resuscitation (CPR) training and awareness of cardiac arrest., Design: A retrospective analysis of a national cross-sectional survey was undertaken. Data were collected online from adults in July 2017 as part of the Heart Foundation of Australia's HeartWatch survey. We used logistic regression to examine demographic factors associated with CPR training., Participants: A national cohort was invited to participate in the survey using purposive, non-probability sampling methods with quotas for age, gender and area of residence, in order to reflect the wider Australian population. The final sample consisted of 1076 respondents., Main Outcome Measure: To determine an estimation of the prevalence of cardiac arrest awareness and CPR training at a national level and the relationship of training to demographic factors., Results: The majority (76%) of respondents were born in Australia with 51% female and 66% aged between 35 and 64 years. Only 16% of respondents could identify the difference between a cardiac arrest and a heart attack. While 56% reported previous CPR training, only 22% were currently trained (within 1 year). CPR training was associated with younger age (35 to 54 years) (OR 1.45, 95% CI 1.06 to 2.0), being born in Australia (OR 1.59, 95% CI 1.17 to 2.17) and higher levels of education (university, OR 1.86, 95% CI 1.35 to 2.57). CPR training increased confidence in respondents ability to perform effective CPR and use a defibrillator. Lack of CPR training was the most common reason why respondents would not provide CPR to a stranger., Conclusions: There is a need to improve the community's understanding of cardiac arrest, and to increase awareness and training in CPR. CPR training rates have not changed over the past decades-new initiatives are needed., Competing Interests: Competing interests: JF and JB hold appointments with the International Liaison Committee on Resuscitation (ILCOR). JF holds an Adjunct Research Professor appointment with St John Western Australia., (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2020
- Full Text
- View/download PDF
30. Association of School Physical Activity Policies With Student Physical Activity Behavior.
- Author
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Ganzar LA, Ranjit N, Saxton D, and Hoelscher DM
- Subjects
- Adolescent, Child, Cross-Sectional Studies, Female, Health Policy, Humans, Male, Surveys and Questionnaires, Child Behavior physiology, Exercise physiology, Schools standards, Students psychology
- Abstract
Background : Few studies have examined school physical activity policies to assess dose-response on student outcomes. The purpose of this study was to evaluate the association between health-promoting physical activity policies in elementary schools and physical activity behavior. Methods : In this cross-sectional study, physical activity was assessed using self-report measures in fourth-grade students in Texas (N = 1958, x = 9.66 y) from the School Physical Activity and Nutrition (SPAN) survey. School policies were assessed using the number of health-promoting policies in place taken from the SPAN School Health Survey with principals and their proxies. Multiple linear regressions adjusted for student- and school-level confounders and school clustering were performed. Results : School physical activity policies were significantly associated with student-level physical activity behavior ( P < .05), even after controlling for the student- and school-level confounding variables. The interactions between physical activity policy-by-economic disadvantage ( P < .01) and between physical activity policy-by-geographic strata ( P < .01) were both significant, with stronger direct effects of policies on student physical activity for economically disadvantaged schools and major urban schools. Conclusion : Results from this study provide evidence for the importance of school-based health policies and practices in potentially reducing health disparities, especially in low-income and urban schools.
- Published
- 2019
- Full Text
- View/download PDF
31. Perceived Parental and Peer Social Support Is Associated With Healthier Diets in Adolescents.
- Author
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Haidar A, Ranjit N, Saxton D, and Hoelscher DM
- Subjects
- Adolescent, Cross-Sectional Studies, Female, Health Knowledge, Attitudes, Practice, Humans, Male, Texas epidemiology, Adolescent Behavior psychology, Diet, Healthy psychology, Diet, Healthy statistics & numerical data, Parents, Peer Group, Social Support
- Abstract
Objective: Investigate associations between perceived parental/peer support for a healthy diet and adolescent dietary behaviors using data from the 2009-2011 School Physical Activity and Nutrition (SPAN) survey., Design: A secondary analysis of SPAN, a cross-sectional statewide study using a validated self-administered questionnaire, assessed obesity-related behaviors., Setting: Probability-based sample of Texas 8th- and 11th-grade students., Participants: A total of 6,716 8th- and 11th-grade students., Main Outcome Measures: Obtained by self-report and included sugary beverage consumption, fruit and vegetable intake, and SPAN healthy eating score., Analysis: Multiple logistic regression and linear regression were used to determine associations, controlling for demographic variables., Results: For every 1-point increase in parental support (range, 0-12), adolescents had 1.19 times higher odds of consuming ≥1 fruits or vegetables/d (P < .001) and 1.1 times lower odds of consuming ≥2 sugary beverages/d (P < .05), and had a SPAN healthy eating score (range, -100 to 100) that was 1.6 points higher (P < .001). For every 1-point increase in peer support, adolescents had 1.14 times higher odds of consuming ≥1 fruits and vegetables/d (P < .001) and a higher SPAN healthy eating score (P < .05)., Conclusions and Implications: Parental/peer support was associated with healthier dietary behaviors. Future research could conduct pre-post intervention studies to determine whether an increase in parental/peer support is associated with positive changes in healthier eating., (Copyright © 2018 Elsevier Ltd. All rights reserved.)
- Published
- 2019
- Full Text
- View/download PDF
32. A Rhinofacial Conidiobolus coronatus Fungal Infection Presenting as an Intranasal Tumour.
- Author
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Deak L, Mudalagiriyappa S, Ballin A, Saxton D, and Chakrabarti A
- Subjects
- Adult, Amphotericin B therapeutic use, Antifungal Agents therapeutic use, Conidiobolus pathogenicity, Humans, Male, Mycoses drug therapy, Mycoses physiopathology, Nasal Cavity abnormalities, Nasal Cavity physiopathology, Neoplasms diagnosis, Neoplasms physiopathology, Tomography, X-Ray Computed methods, United Arab Emirates, Zygomycosis physiopathology, Mycoses diagnosis, Zygomycosis diagnosis
- Abstract
Conidiobolomycosis is a rare fungal infection that affects adults in tropical regions. We report a 42-year-old male patient who was referred to the Sulaiman Al Habib Hospital, Dubai, United Arab Emirates (UAE), in 2013 with excessive nasal bleeding and a suspected nasal tumour. He reported having briefly visited central India nine months previously. Computed tomography and magnetic resonance imaging showed a highly vascularised mass in the nasal cavity. However, after surgical excision, initial treatment with amphotericin B deoxycholate was unsuccessful and the disease progressed, leading to external and internal nasal deformation and necessitating further excision and facial reconstruction. Histopathological analysis of the second biopsy revealed Splendore-Hoeppli changes consistent with a fungal infection. Microbiological findings subsequently confirmed Conidiobolus coronatus . Subsequently, the patient was successfully treated with a combination of itraconazole and fluconazole. To the best of the authors' knowledge, this is the first report of a case of rhinofacial conidiobolomycosis from the UAE.
- Published
- 2018
- Full Text
- View/download PDF
33. Socioeconomic inequalities in children's diet: the role of the home food environment.
- Author
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Ranjit N, Wilkinson AV, Lytle LM, Evans AE, Saxton D, and Hoelscher DM
- Subjects
- Body Mass Index, Child, Educational Status, Female, Food Preferences, Food Supply, Humans, Male, Meals, Nutritional Status, Socioeconomic Factors, Texas, Diet standards, Environment, Feeding Behavior, Parents, Residence Characteristics, Social Class, Social Environment
- Abstract
Background: It is well documented in the literature that low socioeconomic status (SES) is associated with lower consumption of healthy foods and that these differences in consumption patterns are influenced by neighborhood food environments. Less understood is the role that SES differences in physical and social aspects of the home food environment play in consumption patterns., Methods: Using data on 4th grade children from the 2009-2011 Texas School Physical Activity and Nutrition (SPAN) study, we used mixed-effects regression models to test the magnitude of differences in the SPAN Health Eating Index (SHEI) by parental education as an indicator of SES, and the extent to which adjusting for measures of the home food environment, and measures of the neighborhood environment accounted for these SES differences., Results: Small but significant differences in children’s SHEI by SES strata exist (-1.33 between highest and lowest SES categories, p<0.01). However, incorporating home food environment and neighborhood environment measures in this model eliminates these differences (-0.7, p=0.145). Home food environment explains a greater portion of the difference. Both social (mealtime structure) and physical aspects (food availability) of the home food environment are strongly associated with consumption of healthy and unhealthy foods., Conclusions: Our findings suggest that modifiable parent behaviors at home can improve children’s eating habits and that the neighborhood may impact diet in ways other than through access to healthy food.
- Published
- 2015
- Full Text
- View/download PDF
34. The association between sport participation and dietary behaviors among fourth graders in the school physical activity and nutrition survey, 2009-2010.
- Author
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Dortch KS, Gay J, Springer A, Kohl HW 3rd, Sharma S, Saxton D, Wilson K, and Hoelscher D
- Subjects
- Carbonated Beverages statistics & numerical data, Child, Cross-Sectional Studies, Female, Fruit, Humans, Male, Nutrition Surveys, Texas epidemiology, Vegetables, Diet statistics & numerical data, Schools statistics & numerical data, Sports statistics & numerical data
- Abstract
Purpose: To determine the association between youth sport team participation and dietary behaviors among elementary school-aged children., Design: Cross-sectional survey., Setting: Public schools in Texas during 2009-2010., Subjects: A total of 5035 ethnically diverse fourth graders., Measures: Participation in organized sports teams, consumption of select food items (fruits, vegetables, beverages, sweets/snacks)., Analysis: Multiple logistic regression was used to assess the association between each food item (eaten at least once on the previous day) and number of sports teams as the independent class variable (0, 1 ,2, ≥3), adjusting for body mass index physical activity, socioeconomic status, and ethnicity., Results: Significant dose-response associations were observed between number of sports teams and consumption of fruits and vegetables. For boys, the likelihood of eating fruit and fruit-flavored drinks was significantly higher and the odds of drinking soda were lower with the number of teams. For girls, the likelihood of consuming green vegetables increased as sports teams participation increased, and participation was positively associated with diet soda consumption. A positive association was observed between the number of sports teams and scores on the Healthy Food Index for boys and girls., Conclusion: The findings that sports participation is associated with consumption of fruits and vegetables and lower consumption of soda suggest that efforts should be focused on supporting youth team sports to promote healthier food choices. Since sports are available to all ages, sports may be an important venue for promoting healthier dietary behaviors.
- Published
- 2014
- Full Text
- View/download PDF
35. Comparison of Postoperative Pain in Children with Two Intracapsular Tonsillotomy Techniques and a Standard Tonsillectomy: Microdebrider and radiofrequency tonsillotomies versus standard tonsillectomies.
- Author
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Deak L, Saxton D, Johnston K, Benedek P, and Katona G
- Abstract
Objectives: The aim of this study was to compare the duration and severity of postoperative pain for two different tonsillotomy techniques (radiofrequency [RF] and microdebrider [MD]) with the standard tonsillectomy., Methods: This non-randomised retrospective study, carried out from February 2011 to September 2012, investigated 128 children in two independent centres: Heim Pál Children's Hospital in Budapest, Hungary, and Muscat Private Hospital in Muscat, Oman. Those undergoing conventional tonsillectomies acted as the control group. One centre tested the MD technique (n = 28) while the other centre tested the RF technique (n = 31)., Results: The pain-free period after the tonsillotomies was similar between the two techniques and ranged up to three days. Other indicators of pain resolution, like the use of a single analgesic, reduced night-time waking and the time taken to resume a normal diet, were also similar for the two groups. However, patients benefited significantly from having a tonsillotomy rather than a tonsillectomy., Conclusion: The partial resectioning of tonsillar tissue using the MD and RF techniques showed promising outcomes for a better postoperative quality of life when compared to a traditional tonsillectomy. In this study, the results of both the MD and RF tonsillotomy methods were almost identical in terms of the duration of postoperative pain and recovery time.
- Published
- 2014
36. Self-test. Caring for patients with cardiovascular problems.
- Author
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Saxton DF
- Subjects
- Humans, Cardiovascular Diseases nursing, Education, Nursing, Continuing, Educational Measurement
- Published
- 1996
37. Accuracy of ultrasound measurements of female pelvic organs.
- Author
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Saxton DW, Farquhar CM, Rae T, Beard RW, Anderson MC, and Wadsworth J
- Subjects
- Adult, Endometrium pathology, Female, Humans, Hysterectomy, Ovariectomy, Pelvic Inflammatory Disease pathology, Polycystic Ovary Syndrome pathology, Postoperative Period, Ovary pathology, Ultrasonography standards, Uterus pathology
- Abstract
Uterine size, endometrial thickness and ovarian volume were measured ultrasonically and the results compared with caliper measurements made shortly afterwards at the time of total hysterectomy and bilateral salpingo-oophorectomy. The results establish the validity of ultrasound measurements. Histological studies also confirmed the diagnosis made with ultrasound of polycystic ovaries in women complaining of pain due to pelvic congestion.
- Published
- 1990
- Full Text
- View/download PDF
38. A potential microneurosurgical method for the manipulation of the developing nervous system of the postimplantation mouse embryo in utero. I. Injection methods.
- Author
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Ilgren EB, Saxton DG, Jones AE, and Duckworth SD
- Subjects
- Animals, Embryonic Development, Female, Injections methods, Injections, Intraventricular methods, Mice, Mice, Inbred C3H, Microsurgery methods, Pregnancy, Transplantation methods, Brain embryology, Embryo, Mammalian surgery, Embryology methods, Neurosurgery methods
- Abstract
A microsurgical method for the injection of cells into the postimplantation mouse embryo whilst it is in utero is described. Specific regions of the 9.5-day-old mouse embryo brain have been injected with marker substances, such regions including the intraventricular cavity of the telencephalon and the trigeminal facialis ganglion bulge of the forebrain. Histological study of the injected embryos shows that the injection method is precise and able to avoid damage to other nearly embryonic tissues. The method should have wide application in the study of questions of normal cell lineage, neoplasia, teratology, and toxicology.
- Published
- 1985
- Full Text
- View/download PDF
39. The political challenges for associate degree nursing: issues of the present, direction for the future. Summary and future direction.
- Author
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Saxton D
- Subjects
- American Nurses' Association, United States, Education, Nursing, Associate trends, Politics
- Published
- 1980
40. Collective bargaining in academe: a personal appraisal.
- Author
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Saxton DF
- Subjects
- Faculty, Nursing, Labor Unions, New York, Collective Bargaining, Faculty, Universities
- Published
- 1973
41. The process of collective bargaining and its effects on a conservative faculty member.
- Author
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Saxton DF
- Subjects
- Collective Bargaining, Faculty, Nursing, Labor Unions, United States
- Published
- 1973
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