Search

Your search keyword '"Saxinger, W.C."' showing total 9 results
Start Over Author "Saxinger, W.C."
9 results on '"Saxinger, W.C."'

3. Subgroup G HIV Type 1 Isolates from Nigeria

Author

ABIMIKU, A.G., primary, STERN, T.L., additional, ZWANDOR, A., additional, MARKHAM, P.D., additional, CALEF, C., additional, KYARI, S., additional, SAXINGER, W.C., additional, GALLO, R.C., additional, ROBERT-GUROFF, M., additional, and REITZ, M.S., additional

Published
1994
Full Text
View/download PDF

5. Serum IgD elevation is an early marker of B cell activation during infection with the human immunodeficiency viruses.

Author

Mizuma, H., Zolla-Pazner, Susan, Litwin, S., Wafaa El-Sadr, Sharpe, Sandra, Zehr, B., Weiss, S., Saxinger, W.C., and Marmor, M-

Subjects
SERUM, B cells, HIV, AIDS, HYPERGAMMAGLOBULINEMIA, LYMPHOCYTES
Abstract

IgD levels in individuals infected with the human immunodeficiency viruses (HIV) were studied as a means of monitoring the character and timing of B cell activation in individuals with this infection. Significantly increased levels of IgD were characteristic of homosexual men who were HIV seropositive but asymptomatic or mildly symptomatic. The hyper IgD globulinaemia became progressively more pronounced in patients with increasingly severe infection and reached its most marked level in patients with AID Sreiated complex (ARC), In ARC patients, IgD levels were increased 8-8-fold above normal which was disproportionately greater than the 2 4-fold increase in IgG, the 1-8- fold increase in IgA and the 1-6-fold increase in IgM. IgD levels declined in AIDS patients (although remained elevated compared to controls). The data suggest that an unusual type of B cell activation is responsible for the unique pattern of hypergammaglobulinaemia seen in this disease and that the B cell activation occurs early in the pathogenesis of HIV infection, often before development of symptoms, and continues throughout the course of infection. [ABSTRACT FROM AUTHOR]

Published
1987

7. Letter to the Editor

Author

Josephs, S.F., primary, Schlar, L., additional, Ablashi, D.V., additional, Saxinger, W.C., additional, Streicher, H.Z., additional, and Salahuddin, S.Z., additional

Published
1988
Full Text
View/download PDF

8. Isolation and tissue distribution of type-C virus and viral components from a gibbon ape (Hylobates lar) with lymphocytic leukemia

Author

Gallo, R.C., primary, Gallagher, R.E., additional, Wong-Staal, F., additional, Aoki, T., additional, Markham, P.D., additional, Schetters, H., additional, Ruscetti, F., additional, Valerio, M., additional, Walling, M.J., additional, O'Keeffe, R.T., additional, Saxinger, W.C., additional, Guy Smith, R., additional, Gillespie, D.H., additional, and Reitz, M.S., additional

Published
1978
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results