1. A Case of Composite Lymphoma with Extranodal NK/T-cell Lymphoma, Nasal-type and Diffuse Large B-cell Lymphoma
- Author
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Akifumi Ichiki, Daisuke Furuya, Daisuke Ogiya, Shohei Kawakami, Sawako Shiraiwa-Hara, Rikio Suzuki, Shinichiro Machida, Makoto Onizuka, Hiromichi Matsushita, Yoshiaki Ogawa, Naoya Nakamura, Hiroshi Kawada, Yasuyuki Aoyama, Ryujiro Hara, Hidetsugu Kawai, Kiyoshi Ando, and Yukari Shirasugi
- Subjects
0301 basic medicine ,Nose Neoplasms ,Case Report ,medicine.disease_cause ,Extranodal NK/T-cell lymphoma, nasal type ,Composite lymphoma ,03 medical and health sciences ,0302 clinical medicine ,immune system diseases ,hemic and lymphatic diseases ,medicine ,Epstein-Barr virus ,Humans ,Neoplasm Invasiveness ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Epstein–Barr virus ,Immunohistochemistry ,Lymphoma ,Extranodal NK/T-cell lymphoma, nasal-type ,Lymphoma, Extranodal NK-T-Cell ,Therapy management ,030104 developmental biology ,030220 oncology & carcinogenesis ,Cancer research ,Female ,Lymphoma, Large B-Cell, Diffuse ,business ,Diffuse large B-cell lymphoma - Abstract
Composite lymphoma (CL) is defined as the occurrence of two distinct types of lymphoma within the same patient. Most cases of CL involve Hodgkin and non-Hodgkin lymphomas or two distinct types of B-cell lymphomas; true CL is a composite B-cell and T-cell lymphoma, and is rare. We herein report a case involving concurrent extranodal NK/T-cell lymphoma, nasal-type and diffuse large B-cell lymphoma, which has not been previously reported. As the mechanisms and treatments of composite B-cell and T-cell lymphomas are unclear, further studies are required to improve the prognosis.
- Published
- 2019