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Your search keyword '"Satoskar, Rohit S."' showing total 22 results
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22 results on '"Satoskar, Rohit S."'

1. Bartonella quintana Infection in Kidney Transplant Recipients from Donor Experiencing Homelessness, United States, 2022

Author

Beeson, Amy M., Rich, Shannan N., Russo, Michael E., Bhatnagar, Julu, Kumar, Rebecca N., Ritter, Jana M., Annambhotla, Pallavi, Takeda, Moe R., Kuhn, Kira F., Pillai, Prishanya, DeLeon- Carnes, Marlene, Scobell, Rebecca, Ekambaram, Maheswari, Finkel, Rachel, Reagan-Steiner, Sarah, Martines, Roosecelis B., Satoskar, Rohit S., Vranic, Gayle M., Mohammed, Raji, Rivera, Gloria E., Cooper, Kumarasen, Abdelal, Heba, Couturier, Marc Roger, Bradley, Benjamin T., Hinckley, Alison F., Koehler, Jane E., Mead, Paul S., Kuehnert, Matthew J., Ackelsberg, Joel, Basavaraju, Sridhar V., and Marx, Grace E.

Subjects
Transplantation of organs, tissues, etc. -- Complications and side effects, Verruga peruana -- Diagnosis -- Care and treatment, Homelessness -- Health aspects, Lice -- Health aspects, Medical screening -- Methods, Health
Abstract

Bartonella quintana is a small, facultatively intracellular, gram-negative bacillus that is transmitted to humans through the feces of an infected human body louse (Pediculus humanus corporis) (1). B. quintana infection [...]

Published
2024

6. Alcohol‐associated liver disease predicts increased post‐liver transplant opioid use

Author

Johnson‐Laghi, Krystina A., primary, Woo, Stephanie M., additional, Zafar, Zaeema, additional, Fernandez, Stephen, additional, Desale, Sameer, additional, Robertazzi, Suzanne E., additional, Smith, Coleman I., additional, Thomas, Arul M., additional, Lalos, Alexander T., additional, Georgia, Sarah J., additional, Jenkins, Michelle L., additional, Faust, Thomas W., additional, Fishbein, Thomas M., additional, Satoskar, Rohit S., additional, Rangnekar, Amol S., additional, and Hsu, Christine C., additional

Published
2022
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7. Bridging and downstaging with TACE in early and intermediate stage hepatocellular carcinoma: Predictors of receiving a liver transplant.

Author

Yin, Chao, Armstrong, Samantha, Shin, Richard, Geng, Xue, Wang, Hongkun, Satoskar, Rohit S., Fishbein, Thomas, Smith, Coleman, Banovac, Filip, Kim, Alexander Y., and He, Aiwu Ruth

Abstract

Background and Aims: In patients with surgically unresectable early and intermediate stage hepatocellular carcinoma (HCC), only liver transplant (LT) offers a cure. Locoregional therapies, such as transarterial chemoembolization (TACE), are widely used to bridge patients waiting for an LT or downstage tumors beyond Milan Criteria (MC). However, there are no formal guidelines on the number of TACE procedures patients should receive. Our study explores the extent to which repeated TACE might offer diminishing gains toward LT. Approach: We retrospectively analyzed 324 patients with BCLC stage A and B HCC who had received TACE with the intention of disease downstaging or bridging to LT. In addition to baseline demographics, we collected data on LT status, survival, and the number of TACE procedures. Overall survival (OS) rates were estimated using the Kaplan‐Meier method, and correlative studies were calculated using chi‐square or Fisher's exact test. Results: Out of 324 patients, 126 (39%) received an LT, 32 (25%) of whom had responded favorably to TACE. LT significantly improved OS: HR 0.174 (0.094‐0.322, P <.001). However, the LT rate significantly decreased if patients received ≥3 vs < 3 TACE procedures (21.6% vs 48.6%, P <.001). If their cancer was beyond MC after the third TACE, the LT rate was 3.7%. Conclusions: An increased number of TACE procedures may have diminishing returns in preparing patients for LT. Our study suggests that alternatives to LT, such as novel systemic therapies, should be considered for patients whose cancers are beyond MC after three TACE procedures. [ABSTRACT FROM AUTHOR]

Published
2023
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9. Use of a fluorescence spectroscopic readout to characterize the interactions of Cdc42Hs with its target/effector, and mPAK-3

Author

Leonard, David A., Satoskar, Rohit S., Wu, Wen-Jin, Bagrodia, Shubha, Cerione, Richard A., and Manor, Danny

Subjects
Proteins -- Research, Enzymes -- Research, Biological sciences, Chemistry
Abstract

The family of p21-activated kinases (PAKs) have a domain that can independently bind to the Ras-like proteins Cdc42Hs and Rac. A 72 amino acid recombinant form of this p21-binding domain (PBD) from mPAK-3 in Escherichia coli was expressed to examine structure-function relationships. Results indicated that PBD binding changes the geometry of the guanine nucleotide binding site on Cdc42Hs. The catalytic domain of the GTPase activating protein, Cdc42-GAP, was found to inhibit PBD binding in a competitive manner, suggesting that this target molecule and the negative regulator (GAP) bind to overlapping sites of the Cdc42Hs molecule.

Published
1997

10. SAT-471-Hepatic adenomatosis increases risk of hepatic adenoma bleeding

Author

Mcdermott, Chelsea, primary, Hsu, Christine Cho-Shing, additional, Desale, Sameer, additional, Fernandez, Stephen, additional, Ertreo, Marco, additional, Jha, Reena C., additional, Satoskar, Rohit S., additional, Lalos, Alexander T., additional, Rangnekar, Amol S., additional, Thomas, Arul M., additional, Smith, Coleman I., additional, and Faust, Thomas W., additional

Published
2019
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