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Byline: Swati. Chhabra, Naveen. Malhotra, Sukhminder. Singh Bajwa, Sanjay. Choubey, Shibu. Sasidharan, Neeru. Sahni Anaesthesiology is a high-demand speciality of medicine in terms of long and unpredictable work hours, stressful [...]

Byline: Ankita. Sharma, Priyanka. Sharma, Shibu. Sasidharan Sir, We report a case of Winchester syndrome for femur fracture fixation, which was successfully managed in our hospital. It was interesting because [...]

Byline: Shalendra. Singh, Nitesh. Kumar, Debashish. Paul, Shibu. Sasidharan Sir, For optimal visualisation during operative hysteroscopy, liquid distension media like 1.5% glycine/Cytal (Mannitol + sorbitol) are used.[1] Though 1.5% glycine [...]

Background. Infertility and its treatment are frequently associated with psychological distress. We assessed the prevalence of anxiety and depression in couples undergoing treatment for infertility with assisted reproductive techniques (ARTs). Methods. We included 160 married couples undergoing treatment for infertility at an ART centre. The prevalence of anxiety and depression was assessed using the hospital anxiety and depression scale. Results. The prevalence of anxiety and depression was 46.2% and 40.9%, respectively. Women had higher mean (SD) anxiety (10.76 [2.69]) and depression (9.86 [2.06]) scores; however, this gender difference was statistically significant only with respect to anxiety (p=0.02). The mean anxiety scores were highest among both genders when the cause of infertility was attributed to both partners and during the first year and 10 years after treatment. Men in the age groups of 20-24 years and 40-44 years and those with no prior treatment had a statistically significant association with the highest anxiety scores. The mean depression scores showed a statistically significant decline in both genders with increasing age. Among men, the mean depression scores were significantly higher in those with no prior treatment, male cause of infertility and during the first year and after 10 years of treatment. Conclusion. The prevalence of anxiety and depression among infertile couples undergoing treatment with ART was almost twice as high as that in the general population. The mean anxiety scores were significantly associated with duration of treatment and gender-based attribution in both genders; however, age and prior treatment were associated with only men. The mean scores of depression were significantly associated with age in both genders, while duration of treatment, gender-based attribution and prior treatment were significantly associated only with men. [ABSTRACT FROM AUTHOR]

Byline: Shalendra. Singh, Pothireddy. Sreenivasulu, Saurabh. Sud, Shibu. Sasidharan, Ankur. Gupta We present a rare case of dengue hemorrhagic fever presenting with severe myocardial dysfunction along with intracranial hemorrhage and [...]

Background. Advanced diagnostics are not easily accessible in austere topographical locations. We documented retinal changes in patients with acute mountain sickness (AMS+) and compared these with asymptomatic individuals (AMS-) with recent induction into high altitude using direct ophthalmoscopy as a screening tool. Methods. We evaluated 97 individuals (43 AMS- and 54 AMS + ) who were inducted to an altitude 3800 m above sea level by direct ophthalmoscopy after pupillary dilatation, on day 2 of arrival. Results. Retinal vein dilatation was seen in 36 (66.7%) AMS+ v. 14 (32.6%) AMS- (p<0.01), hyperaemia of the optic disc in 30 (55.6%) AMS+ v. 14 (32.6%) AMS-(p<0.05), hyperaemia of the optic disc along with retinal vein dilatation in 27 (50%) AMS+ v. 9 (20.9%) AMS-(p<0.01), retinal vein tortuosity in 12 (22.2%) AMS+ v. 3 (7%) AMS- (p<0.02). In AMS+ with retinal vein dilatation 17 (50%) had SpO2 >91% and 19 (79.2%) had SpO2 <91% (p<0.01). An AMS score of ≥5 was recorded in 25 (69.4%; p<0.001) with venular dilatation and in 19 (52.8%; p<0.001) who were AMS+ with an induction number ≥3 had retinal dilatation. Conclusion. Acute hypobaric hypoxia causes retinal venous dilatation, tortuosity and hyperaemia of the optic disc in those with AMS and correlates directly with SpO2 levels. The incidence of retinal vein dilatation increases with frequent re-entry into high altitude and more severe symptoms of AMS. Hence, all those being inducted to high altitude should be screened for retinal vascular changes. [ABSTRACT FROM AUTHOR]

DRC's fight with the EVD (Ebola Virus Disease) was just settling when WHO declared COVID-19 to be a Public Health Emergency of International Concern (PHEIC) on March 12, 2020. DRC's economic growth decelerated from its pre-COVID level of 4.4% in 2019 to an estimated 0.8% in 2020. This has caused concomitant setbacks in the treatment and control of major health issues like HIV, tuberculosis, measles, rift valley fever and malaria in the country. This, coupled with civil unrest, other infectious diseases and risk to the safety of the health workers is a recipe for a 'perfect storm' waiting to unfold. [ABSTRACT FROM AUTHOR]

Preterm birth is associated with significant perinatal morbidity and mortality. Spontaneous preterm birth accounts for up to 75% of all preterm births. Several maternal and fetal characteristics have been associated with preterm birth. With a better understanding of the pathophysiology of preterm birth, various biochemical markers have been studied extensively to predict preterm birth efficiently to intervene appropriately and timely in the cases that would benefit from treatment. This paper provides a summary of the current literature on the use of biochemical markers in predicting spontaneous preterm birth in symptomatic and high-risk-asymptomatic women. For this review, we searched the Cochrane, Medline, PubMed databases and we have included studies from 2009 to date mentioning these important markers in predicting preterm labor. Evidence from the literature suggests cervicovaginal fetal fibronectin, interleukin-6, phosphorylated Insulin-like growth factor binding protein-1, placental alpha macroglobulin-1, and serumα-fetoprotein are promising biochemical markers in predicting spontaneous preterm birth. [ABSTRACT FROM AUTHOR]