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31 results on '"Sarkozy, Margot"'

1. ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis

Author

Barisic, Darko, Chin, Christopher R., Meydan, Cem, Teater, Matt, Tsialta, Ioanna, Mlynarczyk, Coraline, Chadburn, Amy, Wang, Xuehai, Sarkozy, Margot, Xia, Min, Carson, Sandra E., Raggiri, Santo, Debek, Sonia, Pelzer, Benedikt, Durmaz, Ceyda, Deng, Qing, Lakra, Priya, Rivas, Martin, Steidl, Christian, Scott, David W., Weng, Andrew P., Mason, Christopher E., Green, Michael R., and Melnick, Ari

Published
2024
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13. Association Between Intravenous to Oral Opioid Transition Time and Length of Hospital Stay After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis

Author

Hengartner, Astrid C., primary, Havlik, John, additional, David, Wyatt B., additional, Reeves, Benjamin C., additional, Freedman, Isaac G., additional, Sarkozy, Margot, additional, Maloy, Gwyneth, additional, Fernandez, Tiana, additional, Craft, Samuel, additional, Koo, Andrew B., additional, Tuason, Dominick A., additional, DiLuna, Michael, additional, and Elsamadicy, Aladine A., additional

Published
2023
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14. 550 Hospital Frailty Risk Score is an Independent Risk Factor for VP Shunt Placement for Ruptured Intracranial Aneurysms

Author

Koo, Andrew B., primary, Elsamadicy, Aladine A., additional, Sarkozy, Margot, additional, Reeves, Benjamin, additional, Craft, Samuel, additional, Sherman, Josiah, additional, Sayeed, Sumaiya, additional, Antonios, Joseph Paul, additional, Renedo, Daniela, additional, Sujijantarat, Nanthiya, additional, Hebert, Ryan Matthew, additional, Malhotra, Ajay, additional, and Matouk, Charles Christian, additional

Published
2023
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15. Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Primary Spinal Intradural/Cord Tumors.

Author

Elsamadicy, Aladine A., Koo, Andrew B., Reeves, Benjamin C., Pennington, Zach, Sarkozy, Margot, Hersh, Andrew, Havlik, John, Sherman, Josiah J. Z., Goodwin, C. Rory, Kolb, Luis, Laurans, Maxwell, Larry Lo, Sheng-Fu, Shin, John H., and Sciubba, Daniel M.

Subjects
DISEASE risk factors, FRAILTY, SPINAL surgery, SPINAL cord tumors, HOSPITAL costs, UMBILICAL cord clamping
Abstract

Objective: The Hospital Frailty Risk Score (HFRS) is a metric that measures frailty among patients in large national datasets using ICD-10 codes. While other metrics have been utilized to demonstrate the association between frailty and poor outcomes in spine oncology, none have examined the HFRS. The aim of this study was to investigate the impact of frailty using the HFRS on complications, length of stay, cost of admission, and discharge disposition in patients undergoing surgery for primary tumors of the spinal cord and meninges. Methods: A retrospective cohort study was performed using the Nationwide Inpatient Sample database from 2016 to 2018. Adult patients undergoing surgery for primary tumors of the spinal cord and meninges were identified using ICD-10-CM codes. Patients were categorized into 2 cohorts based on HFRS score: Non-Frail (HFRS<5) and Frail (HFRS≥5). Patient characteristics, treatment, perioperative complications, LOS, discharge disposition, and cost of admission were assessed. Results: Of the 5955 patients identified, 1260 (21.2%) were Frail. On average, the Frail cohort was nearly 8 years older (P <.001) and experienced more postoperative complications (P =.001). The Frail cohort experienced longer LOS (P <.001), a higher rate of non-routine discharge (P =.001), and a greater mean cost of admission (P <.001). Frailty was found to be an independent predictor of extended LOS (P <.001) and non-routine discharge (P <.001). Conclusion: Our study is the first to use the HFRS to assess the impact of frailty on patients with primary spinal tumors. We found that frailty was associated with prolonged LOS, non-routine discharge, and increased hospital costs. [ABSTRACT FROM AUTHOR]

Published
2023
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18. Differences in Health Care Resource Utilization After Surgery for Metastatic Spinal Column Tumors in Patients with a Concurrent Affective Disorder in the United States

Author

Elsamadicy, Aladine A., primary, Koo, Andrew B., additional, Sarkozy, Margot, additional, Reeves, Benjamin C., additional, Pennington, Zach, additional, Havlik, John, additional, Sandhu, Mani R., additional, Hersh, Andrew, additional, Patel, Saarang, additional, Kolb, Luis, additional, Larry Lo, Sheng-Fu, additional, Shin, John H., additional, Mendel, Ehud, additional, and Sciubba, Daniel M., additional

Published
2022
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19. Higher Hospital Frailty Risk Score is associated with increased complications and healthcare resource utilization after endovascular treatment of ruptured intracranial aneurysms.

Author

Koo, Andrew B., Elsamadicy, Aladine A., Renedo, Daniela, Sarkozy, Margot, Sherman, Josiah, Reeves, Benjamin C., Havlik, John, Antonios, Joseph, Sujijantarat, Nanthiya, Hebert, Ryan, Malhotra, Ajay, and Matouk, Charles

Subjects
ENDOVASCULAR aneurysm repair, LENGTH of stay in hospitals, FRAIL elderly, RETROSPECTIVE studies, ACQUISITION of data, MEDICAL care costs, MEDICAL care use, MEDICAL records, ADVERSE health care events, INTRACRANIAL aneurysms, LONGITUDINAL method
Abstract

Aim To use the Hospital Frailty Risk Score (HFRS) to investigate the impact of frailty on complication rates and healthcare resource utilization in patients who underwent endovascular treatment of ruptured intracranial aneurysms (IAs). Methods A retrospective cohort study was performed using the 2016-2019 National Inpatient Sample database. All adult patients (≥18 years) undergoing endovascular treatment for IAs after subarachnoid hemorrhage were identified using ICD-10-CM codes. Patients were categorized into frailty cohorts: low (HFRS <5), intermediate (HFRS 5-15) and high (HFRS >15). Patient demographics, adverse events, length of stay (LOS), discharge disposition, and total cost of admission were assessed. Multivariate logistic regression analysis was used to identify independent predictors of prolonged LOS, increased cost, and non-routine discharge. Results Of the 33 840 patients identified, 7940 (23.5%) were found to be low, 20 075 (59.3%) intermediate and 5825 (17.2%) high frailty by HFRS criteria. The rate of encountering any adverse event was significantly greater in the higher frailty cohorts (low: 59.9%; intermediate: 92.4%; high: 99.2%, p<0.001). There was a stepwise increase in mean LOS (low: 11.7±8.2 days; intermediate: 18.7±14.1 days; high: 26.6±20.1 days, p<0.001), mean total hospital cost (low: $62 888±37 757; intermediate: $99 670±63 446; high: $134 937±80 331, p<0.001), and non-routine discharge (low: 17.3%; intermediate: 44.4%; high: 69.4%, p<0.001) with increasing frailty. On multivariate regression analysis, a similar stepwise impact was found in prolonged LOS (intermediate: OR 2.38, p<0.001; high: OR 4.49, p<0.001 )], total hospital cost (intermediate: OR 2.15, p<0.001; high: OR 3.62, p<0.001), and non-routine discharge (intermediate: OR 2.13, p<0.001; high: OR 4.17, p<0.001). Conclusions Our study found that greater frailty as defined by the HFRS was associated with increased complications, LOS, total costs, and non-routine discharge. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Higher Hospital Frailty Risk Score is associated with increased complications and healthcare resource utilization after endovascular treatment of ruptured intracranial aneurysms

Author

Koo, Andrew B, primary, Elsamadicy, Aladine A, additional, Renedo, Daniela, additional, Sarkozy, Margot, additional, Sherman, Josiah, additional, Reeves, Benjamin C, additional, Havlik, John, additional, Antonios, Joseph, additional, Sujijantarat, Nanthiya, additional, Hebert, Ryan, additional, Malhotra, Ajay, additional, and Matouk, Charles, additional

Published
2022
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21. 307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured Aneurysms

Author

Koo, Andrew B., primary, Elsamadicy, Aladine A., additional, Sarkozy, Margot, additional, Sherman, Josiah, additional, Reeves, Benjamin, additional, Freedman, Isaac G., additional, Antonios, Joseph P., additional, Sujijantarat, Nanthiya, additional, Renado, Daniela, additional, Hebert, Ryan M., additional, Malhotra, Ajay, additional, and Matouk, Charles C., additional

Published
2022
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22. 134 Racial Disparities in Healthcare Resource Utilization After Pediatric Cervical and/or Thoracic Spinal Injuries: Is it Black and White?

Author

Elsamadicy, Aladine A., primary, Sandhu, Mani, additional, Freedman, Isaac G., additional, Koo, Andrew B., additional, Hengartner, Astrid, additional, Reeves, Benjamin, additional, Havlik, John, additional, Sarkozy, Margot, additional, Kundishora, Adam, additional, Tuason, Dominick, additional, and DiLuna, Michael, additional

Published
2022
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23. Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Primary Spinal Intradural/Cord Tumors

Author

Elsamadicy, Aladine A., primary, Koo, Andrew B., additional, Reeves, Benjamin C., additional, Pennington, Zach, additional, Sarkozy, Margot, additional, Hersh, Andrew, additional, Havlik, John, additional, Sherman, Josiah J. Z., additional, Goodwin, C. Rory, additional, Kolb, Luis, additional, Laurans, Maxwell, additional, Larry Lo, Sheng-Fu, additional, Shin, John H., additional, and Sciubba, Daniel M., additional

Published
2022
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25. Racial Disparities in Health Care Resource Utilization After Pediatric Cervical and/or Thoracic Spinal Injuries

Author

Elsamadicy, Aladine A., primary, Sandhu, Mani R., additional, Freedman, Isaac G., additional, Koo, Andrew B., additional, Hengartner, Astrid C., additional, Reeves, Benjamin C., additional, Havlik, John, additional, Sarkozy, Margot, additional, Hong, Chris S., additional, Kundishora, Adam J., additional, Tuason, Dominick A., additional, and DiLuna, Michael, additional

Published
2021
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26. Ramifications of Postoperative Dysphagia on Health Care Resource Utilization Following Elective Anterior Cervical Discectomy and Interbody Fusion for Cervical Spondylotic Myelopathy

Author

Elsamadicy, Aladine A., primary, Koo, Andrew B., additional, David, Wyatt B., additional, Freedman, Isaac G., additional, Reeves, Benjamin C., additional, Ehresman, Jeff, additional, Pennington, Zach, additional, Sarkozy, Margot, additional, Laurans, Maxwell, additional, Kolb, Luis, additional, Shin, John H., additional, and Sciubba, Daniel M., additional

Published
2021
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27. Relationship Between Preoperative Anemia and Perioperaive Outcomes Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis

Author

Elsamadicy, Aladine A, primary, Freedman, Isaac G, additional, Koo, Andrew B, additional, David, Wyatt, additional, Havlik, John, additional, Reeves, Benjamin, additional, Sarkozy, Margot, additional, Kundishora, Adam, additional, Sciubba, Daniel M, additional, Kahle, Kristopher T, additional, and DiLuna, Michael, additional

Published
2020
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29. Impact of Pulmonary Risk Factors on Postoperative Outcomes Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis

Author

Elsamadicy, Aladine A, primary, Freedman, Isaac G, additional, Koo, Andrew B, additional, David, Wyatt, additional, Havlik, John, additional, Reeves, Benjamin, additional, Sarkozy, Margot, additional, Kundishora, Adam, additional, Sciubba, Daniel M, additional, Kahle, Kristopher T, additional, and DiLuna, Michael, additional

Published
2020
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