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6. Antibiotic resistance studies of Escherichia coli and Salmonella species isolated from diarrheal patients

Author

loha, Avijit, primary, Rahman, Md. Motiur, primary, Biswas, Anik, primary, Mou, Madhuchhanda Hazra, primary, Rifat, Tafhim Ahmed, primary, Choudhury, Md. Monjurul Habib, primary, Jebin, Farkhanda Mah, primary, Alarm, Foisal Mohammad Mosiul, primary, Sarker, Protup Kumer, primary, Tariquzzaman, Md., primary, Husain, Md. Anwar, primary, Noman, Md. Abdullah Al, primary, and Haroon, Rashid Md., primary

Published
2021
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7. Salmonella Typhi Stool Shedding by Patients With Enteric Fever and Asymptomatic Chronic Carriers in an Endemic Urban Setting.

Author

Khanam, Farhana, Darton, Thomas C, Meiring, James E, Sarker, Protup Kumer, Biswas, Prasanta Kumar, Bhuiyan, Md Amirul Islam, Rajib, Nazmul Hasan, Tonks, Susan, Pollard, Andrew J, Clemens, John D, Qadri, Firdausi, Kumer Sarker, Protup, Kumar Biswas, Prasanta, and Hasan Rajib, Nazmul

Subjects
TYPHOID fever, SALMONELLA typhi, SALMONELLA enterica serovar Typhi, TYPHOID fever diagnosis, RESEARCH, RESEARCH methodology, PUBLIC health, MEDICAL cooperation, EVALUATION research, FECES, COMPARATIVE studies, SALMONELLA, CARRIER state (Communicable diseases), MICROBIAL virulence, EPIDEMIOLOGICAL research, INFECTIOUS disease transmission
Abstract

The burden of Salmonella enterica serotype Typhi (S. Typhi) shedding in stool and its contribution to transmission in endemic settings is unknown. During passive surveillance S. Typhi shedding was seen during convalescence in 332 bacteremic patient with typhoid, although none persisted at 1-year follow-up. Anti-virulence capsule (Vi)-immunoglobulin (Ig) G titers were measured in age-stratified cohort of serosurveillance participants. Systematic stool sampling of 303 participants with high anti-Vi-IgG titers identified 1 asymptomatic carrier with shedding. These findings suggest that ongoing S. Typhi transmission in this setting is more likely to occur from acute convalescent cases, although better approaches are needed to identify true chronic carriers in the community to enable typhoid elimination. [ABSTRACT FROM AUTHOR]

Published
2021
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