311 results on '"Saravia, F."'
Search Results
2. Characterization and evaluation of the recovery process of saturated reverse osmosis membranes by chemical oxidation
- Author
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Beratto-Ramos, A., Jaramillo, K., Zapata, P., Romero, J., Martínez, J., Meléndrez, M.F., Saravia, F., Horn, H., Borquez, R., and Pino-Soto, L.
- Published
- 2025
- Full Text
- View/download PDF
3. Effect of bST administration on plasma concentrations of IGF-I and follicular dynamics and ovulation during the interovulatory cycle of sheep and goats
- Author
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Cox, J.F., Navarrete, F., Carrasco, A., Dorado, J., and Saravia, F.
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- 2019
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4. Equine mesenchymal stem cells derived from endometrial or adipose tissue share significant biological properties, but have distinctive pattern of surface markers and migration
- Author
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Cabezas, J., Rojas, D., Navarrete, F., Ortiz, R., Rivera, G., Saravia, F., Rodriguez-Alvarez, L., and Castro, F.O.
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- 2018
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- View/download PDF
5. 33 Domestic cat embryos cultured without the zona pellucida have an altered protein pattern at the blastocyst stage
- Author
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Veraguas-Dávila, D., primary, Zapata-Rojas, C., additional, Caamaño, D., additional, Saéz-Ruiz, D., additional, Saravia, F., additional, Castro, F. O., additional, and Rodriguez-Alvarez, L., additional
- Published
- 2023
- Full Text
- View/download PDF
6. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions
- Author
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Gorojod, RM, Alaimo, A, Porte Alcon, S, Pomilio, C, Saravia, F, and Kotler, ML
- Published
- 2015
- Full Text
- View/download PDF
7. Interplay between lysosomal, mitochondrial and death receptor pathways during manganese-induced apoptosis in glial cells
- Author
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Gorojod, R. M., Alaimo, A., Porte Alcon, S., Saravia, F., and Kotler, M. L.
- Published
- 2017
- Full Text
- View/download PDF
8. 29 The
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Veraguas-Dávila, D., primary, Saéz-Ruiz, D., additional, Álvarez, M. C., additional, Saravia, F., additional, Castro, F. O., additional, and Rodríguez-Alvarez, L., additional
- Published
- 2022
- Full Text
- View/download PDF
9. Chronic Diarrhea and Metabolic Acidosis Associated With Topiramate Use
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Gil, Gaby S., Caballes, Ana, Saravia F, Estuardo, and Boma, Noella
- Published
- 2017
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- View/download PDF
10. The effect of oviductal fluid on protein tyrosine phosphorylation in cryopreserved boar spermatozoa differs with the freezing method
- Author
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Kumaresan, A., Johannisson, A., Saravia, F., and Bergqvist, A.S.
- Published
- 2012
- Full Text
- View/download PDF
11. Water management for Power‐to‐X
- Author
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Horn, H., primary, Morales, Y., additional, Samanta, P., additional, and Saravia, F., additional
- Published
- 2022
- Full Text
- View/download PDF
12. Treatment of Hydrothermal-Liquefaction Wastewater with Crossflow UF for Oil and Particle Removal
- Author
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Sayegh, A., Merkert, S., Zimmermann, J., Horn, H., and Saravia, F.
- Subjects
Technology ,hydrothermal-liquefaction wastewater ,ceramic membranes ,ddc:600 ,crossflow ultrafiltration ,oil and particle removal - Abstract
This study aims to evaluate the application of ceramic ultrafiltration membranes in the crossflow mode for the separation of particles and oil in water emulsions (free oil droplets and micelles) from hydrothermal-liquefaction wastewater (HTL-WW) from the hydrothermal liquefaction of municipal sewage sludge. The experiments were carried out using one-channel TiO$_{2}$ membranes with pore sizes of 30, 10 and 5 nm. The results showed that the highest stable permeability could be achieved with a membrane-pore size of 10 nm, which experienced less fouling, especially through pore blockage, in comparison to the two other pore sizes. Instead of observing an increase in the permeability, the application of a higher feed temperature as well as backwash cycles led to a clear increase in irreversible fouling due to the presence of surfactants in the HTL-WW. Among several physical and chemical cleaning methods, alkaline cleaning at pH 12 proved to be the most efficient in removing fouling and maintaining stable performance on a long-term basis. Ceramic-membrane ultrafiltration can be considered as an adequate first-stage treatment of real HTL wastewater.
- Published
- 2022
- Full Text
- View/download PDF
13. Application of Chlorine-Resistant Nanofiltration Membrane in Swimming Pool Water Treatment to Minimize the Disinfection By-Products
- Author
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Peng, D., primary, Saravia, F., additional, Abbt-Braun, G., additional, and Horn, H., additional
- Published
- 2015
- Full Text
- View/download PDF
14. Spermadhesin PSP-I/PSP-II heterodimer induces migration of polymorphonuclear neutrophils into the uterine cavity of the sow
- Author
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Rodriguez-Martinez, H., Saravia, F., Wallgren, M., Martinez, E.A., Sanz, L., Roca, J., Vazquez, J.M., and Calvete, J.J.
- Published
- 2010
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- View/download PDF
15. Early signs of neuroinflammation and vascular dysfunction in experimental Alzheimerʼs disease. is the hilus mainly susceptible?: S24-03
- Author
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Saravia, F.
- Published
- 2015
16. Exposure to the seminal plasma of different portions of the boar ejaculate modulates the survival of spermatozoa cryopreserved in MiniFlatPacks
- Author
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Saravia, F., Wallgren, M., Johannisson, A., Calvete, J.J., Sanz, L., Peña, F.J., Roca, J., and Rodríguez-Martínez, H.
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- 2009
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- View/download PDF
17. 25 Effect of roscovitine on the cumulus cells expansion, oocyte maturation and
- Author
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Veraguas-Davila, D., primary, Saez-Ruiz, D., additional, Alvarez, M. C., additional, Saravia, F., additional, Castro, F. O., additional, and Rodriguez-Alvarez, L., additional
- Published
- 2021
- Full Text
- View/download PDF
18. Influence of seminal plasma on the kinematics of boar spermatozoa during freezing
- Author
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Rodríguez-Martínez, H., Saravia, F., Wallgren, M., Roca, J., and Peña, F.J.
- Published
- 2008
- Full Text
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19. Assessment of motility of ejaculated, liquid-stored boar spermatozoa using computerized instruments
- Author
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Tejerina, F., Buranaamnuay, K., Saravia, F., Wallgren, M., and Rodriguez-Martinez, H.
- Published
- 2008
- Full Text
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20. Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse
- Author
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Beauquis, J., Saravia, F., Coulaud, J., Roig, P., Dardenne, M., Homo-Delarche, F., and De Nicola, Alejandro
- Published
- 2008
- Full Text
- View/download PDF
21. Role of NOM in the performance of adsorption-membrane hybrid systems applied for the removal of pharmaceuticals
- Author
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Saravia, F. and Frimmel, F.H.
- Published
- 2008
- Full Text
- View/download PDF
22. Surgical site infection after gastrointestinal surgery in children: An international, multicentre, prospective cohort study
- Author
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Harrison E. M., Drake T. M., Ghosh D., Ademuyiwa A. O., Bhangu A., Fitzgerald J. E., Glasbey J., Borda-Luque G., Costas-Chavarri A., Ntirenganya F., Fergusson S. J., Ingabire J. C. A., Ismail L., Lilford R., Mihaljevic A. L., Morton D., Mutabazi A. Z., Adisa A. O., Ots R., Pinkney T., Poskus T., Shaw C. A., Verjee A., Runigamugabo E., Khatri C., Mohan M., Jaffry Z., Altamini A., Kirby A., Soreide K., Cornick J., Iyer D., King S., Arthur T., Nahar S. N., Waterman A., Lawini I., Rouse T., Correa J. C., Salem H. K., Worku M., Arnaud A., Kalles V., Aguilera M. L., Recinos G., Quek R., Altibi A., Whitaker J., Bent Z., Al-Slaibi I., Tahboub H., Alser O. H., Shu S., Mironescu A., Bratu M., Altwijri A., Alsaggaf M. U., Jubran A. F., Seisay S., Jeyakumar J., Senanayake K., Abdulbagi O., Raptis D., Kong C., Suresh S., Scott M., Grizhja B., Ymeri S., Galiqi G., Klappenbach R., Antezana D., Beleno A. E. M., Costa C., Sanchez B., Aviles S., Modolo M. M., Fermani C. G., Balmaceda R., Villalobos S., Carmona J. M., Hamill D., Deutschmann P., Sandler S., Cox D., Nataraja R., Sharpin C., Ljuhar D., Gray D., Haines M., Niranjan N., D'Amours S., Ashtari M., Franco H., Mitul A. R., Karim S., Aman N. F., Estee M. M., Salma U., Razzaque J., Hamidkanta T., Tori S., Alamin Md. S., Roy S., Al Amin Md. S., Haque M., Faruq A., Iftekhar F., O'Shea M., Padmore G., Jonnalagadda R., Litvin A., Filatau A., Paulouski D., Shubianok M., Shachykava T., Khokha D., Khokha V., Djivoh F., Lawani I., Dossou F., Seto D. M., Gbessi D. G., Noukpozounkou B., Souaibou Y. I., Keke K. R., Hodonou F., Ahounou E., Alihonou T., Denakpo M., Ahlonsou G., Bedada A. G., Nsengiyumva C., Kwizera S., Barendegere V., Choi P., Stock S., Jamal L., Firdouse M., Zani A., Azzie G., Kushwaha S., Agarwal A., Chen T. -L., Yip C., Montes I., Zapata F., Sierra S., Lanau M. I. V., Arango M. C. M., Restrepo I. M., Giraldo R. S. R., Mendozaarango M., Domini E., Karlo R., Mihanovic J., Youssef M., Elfeki H., Thabet W., Sanad A., Tawfik G., Zaki A., Abdel-Hameed N., Mostafa M., Omar M. F. W., Ghanem A., Abdallah E., Denewer A., Emara E., Rashad E., Sakr A., Elashry R., Emile S., Khafagy T., Elhamouly S., Elfarargy A., Mamdouhmohamed A., Saiednagy G., Esam A., Elwy E., Hammad A., Khallaf S., Ibrahim E., Saidbadr A., Moustafa A., Eldosoukymohammed A., Elgheriany M., Abdelmageed E., Al Raouf E. A., Elbanby E., Elmasry M., Morsyfarahat M., Yahyamansor E., Magdyhegazy E., Gamal E., Gamal H., Kandil H., Maherabdelrouf D., Moaty M., Gamal D., El-Sagheer N., Salah M., Magdy S., Salah A., Essam A., Ali A., Badawy M., Ahmed S., Mohamed M., Assal A., Sleem M., Ebidy M., Abdelrazek A., Zahran D., Adam N., Nazir M., Hassanein A. B., Ismail A., Elsawy A., Mamdouh R., Mabrouk M., Ahmed L. A. M., Hassabalnaby M., Magdy E., Abd-Elmawla M., Fahim M., Mowafy B., Mahmoud M. I., Allam M., Alkelani M., El Gendy N. H., Aboul-Naga M. S., Alaael-Din R., Elgendy A. H., Ismail M., Shalaby M., Elsharkawy A. A., Moghazy M. E., Elbisomy K. H., Shakshouk H. A. G., Hamed M. F., Ebidy M. M., Abdelkader M., Karkeet M., Ahmed H., Adel I., Omar M. E., Ibrahim M., Ghoneim O., Hesham O., Gamal S., Hilal K., Arafa O., Awad S. A., Salem M., Elsherif F. A., Elsabbagh N., Aboelsoud M. R., Rida A. H. E. F., Hossameldin A., Hany E., Asar Y. H., Anwar N., Gadelkarim M., Abdelhady S., Morshedy E. M., Saad R., Soliman N., Salama M., Ezzat E., Mohamed A., Ibrahim A., Fergany A., Mohammed S., Reda A., Allam Y., Saad H. A., Abdelfatah A., Fathy A. M., El-Sehily A., Kasem E. A., Hassan A. T. A., Mohammed A. R., Saad A. G., Elfouly Y., Elfouly N., Hassaan A., Mohammed M. M., Elhoseny G., Magdy M., Elkhalek E. A., Zakaria Y., Ezzat T., El Dahab A. A., Kelany M., Arafa S., Hassan O. M. M., Badwi N. M., Sleem A. S., Abdelbadeai K., Abdullah M. A., Lokman M., Bahar S., Radyabdelazeam A., Adelshone A., Hasnan M. B., Zulkifli A., Kamarulzamil S. N. A., Elhendawy A., Latif A., Adnan A. B., Shaharuddin S., Majid A. H. H. A., Amreia M., Al-Marakby D., Salma M., Basir E. R. M., Ali C. D. M., Ata A. Y., Nasr M., Rezq A., Sheta A., Tariq S., Sallam A., Darwish A. K. Z., Elmihy S., El Hadry S., Farag A., Hajah H., Seliem A., Aglan A., Zohair A., Essam M., Moussa O., El-Gizawy E., Samy M., Ali S., Elhalawany E., Ata A., Elhalawany M., Nashat M., Soliman S., Elazab A., Abdelaziz M. A., Ibrahim K., Ibrahim A. M., Gado A., Hantour U., Eldeen E. A., Loaloa M. R., Abouzaid A., Ahmedbahaaeldin M., Hashad E., Sroor F., Gamil D., Mahmoudabdulhakeem E., Zakaria M., Mohamed F., Abubakr M., Ali E., Magdy H., Ramadan M., Abdelatymohamed M., Mansour S., Abdulazizamin H., Rabiemohamed A., Saami M., Ahmedredaelsayed N., Tarek A., Mohyeldeenmahmoud S., El Sayed I. M., Yusufshawky M., Mousasalem M., El-Din S. A., Soliman N. A., Talaat M., Abdelmoenelhusseiny S. A. -D. A., Abdullah N., Elshaar M., Abdelfatahibraheem A., Abdulaziz H., Ismail M. K., Hamdymadkor M., Abdelaty M., Kader S. M., Mohamedsalah O., Eldafrawy M., Zakieldeeb A., Mahmoudeid M., Attia A., El-Dien K. S., Shwky A., Badenjki M. A., Soliman A., Al Attar S. M., Sayed F., Abdelsabour F., Azizeldine M. G., Shawqi M., Hashim A., Aamer A., Raouf A. M. A., Abdelshakour M., Mahmoud B., Mahmoud M. A., Qenawy M., Rashed A. M., Dahy A., Sayed M., Shamsedine A. W., Mohamed B., Hasan A., Saad M. M., Abdulbassit K., Khalidabdelatif N., Elzahed N., Elkashash A., Bekhet N. M., Hafez S., Gad A., Maher M. E., Abdelsameea A., Hafez M., Sabe A., Ahmed A., Shahine A., Dawood K., Gaafar S., Husseiny R., Aboelmagd O., Mesbah N., Emadeldin H., Almeligy A., Bekhet A. H., Hasan D., Alhady K., Sabe A. K., Elnajjar M. A., Aboelella M., Hamsho W., Hassan I., Saad H., Abdelazim G., Mahmoud H., Wael N., Kandil A. M., Magdy A., Saidelkholy S., Adel B., Dabbour K., Elsherbiney S., Mattar O., Abdrabou A. K., Aly M. Y. M., Geuoshy A., Elnagar A., Abdelmotaleb I., Saleh A. A., Mohammedbakry H., Saeed M., Mahmoud S., Tawfik B., Ismail S. A., Zakaria E., Gad M. O., Elhelbawy M., Bassem M., Khaledabdel-Latif N., Maraie N., Elhadary N. M., Semeda N., Rabiemohamed S., Bakry H. M., Essam A. A., Tarek D., Ashour K., Elhadad A., Abdel-Aty A., Rakha I., Matter S. M., Abdelhamed R., Abdelkader O., Soliman Y., Ghanem S., Farouk S. A. M., Ibrahim E. M., El-Taher E., Mahrousbadr M., El-Sawy R. E. A., Bakr A., Al Rafati A. A. R., Saar S., Reinsoo A., Talving P., Seyoum N., Worku T., Fitsum A., Tolonen M., Leppaniemi A., Sallinen V., Parmentier B., Peycelon M., Irtan S., Dardenne S., Robert E., Maillot B., Courboin E., Arnaud A. P., Hascoet J., Abbo O., Kaci A. A., Prudhomme T., Ballouhey Q., Grosos C., Fourcade L., Cecilia T., Jean-Francois C., Helene F. -C., Delforge X., Haraux E., Dousset B., Schiavone R., Gaujoux S., Marret J. -B., Haffreingue A., Rod J., Renaux-Petel M., Lecompte J. -F., Breaud J., Gastaldi P., Taieb C., Claire R., Anis E., Bustangi N., Lopez M., Scalabre A., Grella M. G., Mariani A., Podevin G., Schmitt F., Hervieux E., Broch A., Muller C., Tabiri S., Kojo A. T. T., Bandoh D., Abantanga F., Kyereh M., Asumah H., Appiah E. K., Wondoh P., Gyedu A., Dally C., Amoah K. A. M., Yifieyeh A., Agbedinu K., Owusu F., Amoako-Boateng M., Dayie M., Hagan R., Debrah S., Ohene-Yeboah M., Clegg-Lampety J. -N., Etwire V., Dakubo J., Essoun S., Bonney W., Glover-Addy H., Osei-Nketiah S., Amoako J., Adu-Aryee N., Appeadu-Mensah W., Bediako-Bowan A., Dedey F., Ekow M., Akatibo E., Yakubu M., Kordorwu H. E. K., Asare-Bediako K., Tackie E., Aaniana K., Acquah E., Opoku-Agyeman R., Avoka A., Kusi K., Maison K., Gyamfi F. E., Naabarnabas G., Abdul-Latif S., Taahamoako P., Davor A., Dassah V., Dagoe E., Kwakyeafriyie P., Akoto E., Ackom E., Mensah E., Atkins E. T., Coompson C. L., Ivros N., Ferousis C., Agalianos C., Kyriazanos I., Barkolias C., Tselos A., Tzikos G., Voulgaris E., Lytras D., Bamicha A., Psarianos K., Stefanopoulos A., Patoulias I., Sfougaris D., Valioulis I., Balalis D., Korkolis D., Manatakis D. K., Kyrou G., Karabelias G., Papaskarlatos I. -A., Konstantina K., Zampitis N., Germanos S., Papailia A., Theodosopoulos T., Gkiokas G., Mitroudi M., Panteli C., Feidantsis T., Farmakis K., Kyziridis D., Ioannidis O., Parpoudi S., Gemenetzis G., Parasyris S., Anthoulakis C., Nikoloudis N., Margaritis M., Aguilera-Arevalo M. -L., Coyoy-Gaitan O., Rosales J., Tale L., Soley R., Barrios E., Rodriguez S. T. T., Pazgalvez C., Herreracruz D., Rosenberg G. S., Matheu A., Cohen D. M., Paul M., Charles A., Lam J. C. Y., Yeung M. H. A., Fok C. Y. J., Li K. H. G., Lai A. C. -H., Cheung Y. H. E., Wong H. Y., Leung K. W., Lee T. S. B., Lam W. H., Dao W., Kwok S. H. -W., Chan T. -Y. K., Ng Y. K., Liu Q., Foo C. C., Yang J., Kumar B., Bhatnagar A., Upadhyaya V., Kumar S., Muddebihal U., Dar W., Kc J., Alexander P., Aruldas N., Adella F. J., Rulie A. S., Iskandar F., Setiawan J., Evajelista C. V., Natalie H., Arlindawati, Gunawan R., Karismaningtyas H., Mata L., Andika F., Hasanah A., Widiastini T. A., Purwaningsih N., Mukin A. D. F., Rahmah D., Nurqistan H., Arsyad H., Adhitama N., Jeo W., Sutandi N., Clarissa A., Gultom P. A., Billy M., Haloho A., Amandito R., Johanna N., Lee F., Dorani R. M. N. R., Glynn M., Alherz M., Goh W., Shiwani H. A., Sproule L., Conlon K. C., Bala M., Kedar A., Turati L., Bianco F., Steccanella F., Gallo G., Trompetto M., Clerico G., Papandrea M., Sammarco G., Sacco R., Benevento A., Pata F., Giavarini L., Giglio M. C., Bucci L., Pagano G., Sollazzo V., Peltrini R., Luglio G., Birindelli A., Di Saverio S., Tugnoli G., Paludi M. A., Mingrone P., Pata D., Selvaggi F., Selvaggi L., Pellino G., Di Martino N., Curletti G., Aonzo P., Galleano R., Berti S., Francone E., Boni S., Lorenzon L., Lo Conte A., Balducci G., Confalonieri G., Pesenti G., Gavagna L., Vasquez G., Targa S., Occhionorelli S., Andreotti D., Pata G., Aquilino F., Chetta N., Picciariello A., Abdelkhalek M., Belli A., de Franciscis S., Bigaran A., Favero A., Basso S. M. M., Salusso P., Perino M., Mochet S., Sasia D., Riente F., Migliore M., Merlini D., Basilico S., Corbellini C., Lazzari V., Macchitella Y., Bonavina L., Angelieri D., Coletta D., Falaschi F., Catani M., Reali C., Malavenda M., Del Basso C., Ribaldi S., Coletti M., Natili A., Depalma N., Iannone I., Antoniozzi A., Rossi D., Gui D., Perrotta G., Ripa M., Giardino F. R., Foco M., Vicario E., Coccolini F., Ansaloni L., Nita G. E., Leone N., Bondurri A., Maffioli A., Simioni A., de Boni D., Pasquali S., Goldin E., Vendramin E., Ciccioli E., Tedeschi U., Bortolasi L., Violi P., Campagnaro T., Conci S., Lazzari G., Iacono C., Guglielmi A., Manfreda S., Rinaldi A., Ringressi M. N., Brunoni B., Salamone G., Mangiapane M., de Marco P., la Brocca A., Tutino R., Silvestri V., Licari L., Fontana T., Cocorullo N. F. G., Sileri P., Arcudi C., Bsisu I., Aljboor K., Abusalem L., Alnusairat A., Qaissieh A., Al-Dakka E., Ababneh A., Halhouli O., Yusufali T., Mohammed H., Lando J., Parker R., Ndegwa W., Jokubauskas M., Gribauskaite J., Venskutonis D., Kuliavas J., Dulskas A., Samalavicius N. E., Jasaitis K., Parseliunas A., Nevieraite V., Montrimaite M., Slapelyte E., Dainius E., Riauka R., Subocius Z. D. A., Venclauskas L., Gulbinas A., Bradulskis S., Kasputyte S., Mikuckyte D., Kiudelis M., Zilinskas J., Jankus T., Petrikenas S., Pazusis M., Urniezius Z., Vilcinskas M., Banaitis V. J., Gaizauskas V., Grisin E., Mazrimas P., Rackauskas R., Drungilas M., Lagunavicius K., Lipnickas V., Majauskyte D., Jotautas V., Abaliksta T., Uscinas L., Simutis G., Ladukas A., Danys D., Laugzemys E., Mikalauskas S., Sruogiene E. Z., Visinskas P., Zilinskiene R., Dragatas D., Burmistrovas A., Tverskis Z., Vaicius A., Mazelyte R., Zadoroznas A., Kaselis N., Ziubryte G., Rahantasoa F. C. F. P., Samison L. H., Rasoaherinomenjanahary F., Tolotra T. E. C., Mukuzunga C., Msosa V., Kwatiwani C., Msiska N., Chai F. Y., Asilah S. M. D., Syibrah K. Z., Chin P. X., Salleh A., Riswan N. Z., Roslani A. C., Chong H. -Y., Aziz N. A., Poh K. -S., Chai C. -A., Taher M. M., Kosai N. R., Aziz D. N. A., Rajan R., Julaihi R., Jethwani D. L., Yahaya M. T., Abdullah N. A. N., Mathew S. W., Chung K. J., Nirumal M. K., Tze R. G. E., Ali S. A. W. E. W., Gan Y. Y., Ting J. R. S., Sii S. S. Y., Koay K. L., Tan Y. K., Cheah A. E. Z., Wong C. Y., Mat T. N. T., Chow C. Y. N., Har P. A. L., Der Y., Tew Y. Y., Henry F., Low X., Neo Y. T., Heng H. E., Kong S. N., Gan C., Mok Y. T., Tan Y. W., Palayan K., Devatata M., Cheong Y. J., Gunaseelan K., Nasir W. N. A. W. M., Yoganathan P., Lee E. X., Saw J. E., Yeang L. J., Koh P. Y., Lim S. Y., Teo S. Y., Grech N., Magri D., Cassar K., Mizzi C., Falzon M., Shaikh N., Scicluna R., Zammit S., Borg E., Mizzi S., Brincat S. D., Tembo T., Le V. T. H., Grima T., Sammut K., Carabott K., Farrugia A., Zarb C., Navarro A., Dimech T., Camilleri G., Bertuello I., Dalli J., Bonavia K., Corro-Diaz S., Manriquez-Reyes M., Ramos-De la Medina A., Abdelhamid A., Hrora A., Benammi S., Bachri H., Abbouch M., Boukhal K., Bennai R. M., Belkouchi A., Jabal M. S., Benyaiche C., Vermaas M., Duinhouwer L., Pastora J., Wood G., Merlo M. S., Ajao A., Ayandipo O., Lawal T., Abdurrazzaaq A., Habeeb O., Alada M., Nasir A., Adeniran J., Popoola A., Adeyeye A., Adebanjo A., Adesanya O., Adeniyi A., Mendel H., Bello B., Muktar U., Osinowo A., Olajide T. O., Oshati O., Ihediwa G., Adenekan B., Nwinee V., Alakaloko F., Ademuyiwa A., Elebute O., Lawal A., Bode C., Olugbemi M., Adesina A., Faturoti O., Odutola O., Adebola O., Onuoha C., Taiwo O., Williams O., Balogun F., Ajai O., Oludara M., Njokanma I., Osuoji R., Kache S., Ajah J., Makama J., Adamu A., Baba S., Aliyu M., Aliyu S., Ukwenya Y., Aliyu H., Sholadoye T., Daniyan M., Ogunsua O., Anyanwu L. -J., Sheshe A., Mohammad A., Olori S. D., Mshelbwala P., Odeyemi B., Samson G., Timothy O. K., Samuel S. A., Ajiboye A., Amole I., Abiola O., Olaolorun A., Veen T., Kanani A., Styles K., Herikstad R., Larsen J. W., Soreide J. A., Jensen E., Gran M., Aahlin E. K., Gaarder T., Monrad-Hansen P. W., Naess P. A., Lauzikas G., Wiborg J., Holte S., Augestad K., Banipal G., Monteleone M., Moe T., Schultz J., Al-Taher T., Hamdan A., Salman A., Saadeh R., Musleh A., Jaradat D., Abushamleh S., Hanoun S., Qumbos A. A., Hamarshi A., Taher A. 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B., Moore R., Jennings V., Leusink A., Kariem N., Gouws J., Chu K., Bougard H., Noor F., Dell A., Rayne S., van Straten S., Khamajeet A., Tshisola S. K., Kabongo K., Kong V., Moodley Y., Anderson F., Madiba T., du Plooy F., Hartford L., Chilton G., Karjiker P., Mabitsela M., Ndlovu S., Badicel M., Jaich R., Ruiz-Tovar J., Garcia-Florez L., Otero-Diez J. L., Ramosperez V., Aguadosuarez N., Garcia J. M., Moreno S. C., Collado M. V., Carneros V. J., Septiem J. G., Gonzalez M., Picardo A., Esteban E., Ferrero E., Ortega I., Espin-Basany E., Blanco-Colino R., Andriola V., Lorena I., Contreras E., Garciabernardo C., Pagnozzi J., Sanz S., Miyardeleon A., Dorisme A., Rodicio J., Suarez A., Stuva J., Diazvico T., Fernandez-Vega L., Soldevila-Verdeguer C., Sena-Ruiz F., Pujol-Cano N., Diaz-Jover P., Garcia-Perez J. M., Segura-Sampedro J. J., Pineno-Flores C., Ambrona-Zafra D., Craus-Miguel A., Jimenez-Morillas P., Mazzella A., Jayathilake A. B., Thalgaspitiya S. P. B., Wijayarathna L. 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D., Irwin G., Johnston R., Gani M., Gravante G., Rajmohan S., Majid K., Dindyal S., Smith C., Palliyil M., Patel S., Nicholson L., Harvey N., Baillie K., Shillito S., Kershaw S., Bamford R., Orton P., Reunis E., Tyler R., Soon W., Jama G. M., Dhillon D., Patel K., Nanthakumaran S., Heard R., Chen K. Y., Barmayehvar B., Datta U., Kamarajah S. K., Iftekhartani S., Monaghan E., Donnelly P., Walker M., Parakh J., Blacker S., Kaul A., Paramasivan A., Farag S., Nessa A., Awadallah S., Lim J., Cheankhunng J., Gash K., Kiran R. P., Murray A., Etchill E., Dasari M., Puyana J., Haddad N., Zielinski M., Choudhry A., Caliman C., Beamon M., Duane T., Narayanan R., Swaroop M., Myers J., Deal R., Schadde E., Hemmila M., Napolitano L., To K., Makupe A., Musowoya J., Maimbo M., van der Naald N., Kumwenda D., Reece-Smith A., Otten K., Verbeek A., Prins M., Suarez A. A. B., Deane C., Dijan E., Elfiky M., Koskenvuo L., Thollot A., Limoges B., Capito C., Alexandre C., Kotobi H., Leroux J., Pinnagoda K., Henric N., Azzis O., Rosello O., Francois P., Etienne S., Buisson P., Hmila S., Clegg-Lamptey J. -N., Imoro O., Abem O. E., Papageorgiou D., Soulou V., Asturias S., Pena L., Connor D. B. O., Luc A. R., Russo A. A., Ruzzenente A., Taddei A., Cona C., Bottini C., Pascale G., Rotunno G., Solaini L., Pascale M. M., Notarnicola M., Corbellino M., Sacco M., Ubiali P., Cautiero R., Bocchetti T., Muzio E., Guglielmo V., Morandi E., Mao P., de Luca E., Ali F. M., Strupas K., Kondrotas P., Baltrunas R., Kutkevicius J., Ignatavicius P., Tan C. L., Siaw J. Y., Yam S. Y., Wilson L., Aziz M. R. A., Bondin J., Zorrilla C. D., Majbar A., Sale D., Abdullahi L., Osagie O., Faboya O., Fatuga A., Taiwo A., Nwabuoku E., Bliksoen M., Khan Z. A., Coronel J., Miranda C., Vasquez I., Helguero-Santin L. M., Rickard J., Adedeji A., Alqahtani S., Rath M., van Niekerk M., Koto M. Z., Matos-Puig R., Israelsson L., Schuetz T., Yuksek M. A., Mericliler M., Wolf B., Fairfield C., Yong G. L., Whitehurst K., Redgrave N., Musyoka C. K., Olivier J., Lee K., Cox M., Farhan-Alanie M. M. H., Callan R., Chibuye C., Ali T. H. A., Rekhis S., Rommaneh M., Sam Z. H., Pugliesi T. B., Pardo G., Harrison, E. M., Drake, T. M., Ghosh, D., Ademuyiwa, A. O., Bhangu, A., Fitzgerald, J. E., Glasbey, J., Borda-Luque, G., Costas-Chavarri, A., Ntirenganya, F., Fergusson, S. J., Ingabire, J. C. A., Ismail, L., Lilford, R., Mihaljevic, A. L., Morton, D., Mutabazi, A. Z., Adisa, A. O., Ots, R., Pinkney, T., Poskus, T., Shaw, C. A., Verjee, A., Runigamugabo, E., Khatri, C., Mohan, M., Jaffry, Z., Altamini, A., Kirby, A., Soreide, K., Cornick, J., Iyer, D., King, S., Arthur, T., Nahar, S. N., Waterman, A., Lawini, I., Rouse, T., Correa, J. C., Salem, H. K., Worku, M., Arnaud, A., Kalles, V., Aguilera, M. 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B., Deane, C., Dijan, E., Elfiky, M., Koskenvuo, L., Thollot, A., Limoges, B., Capito, C., Alexandre, C., Kotobi, H., Leroux, J., Pinnagoda, K., Henric, N., Azzis, O., Rosello, O., Francois, P., Etienne, S., Buisson, P., Hmila, S., Clegg-Lamptey, J. -N., Imoro, O., Abem, O. E., Papageorgiou, D., Soulou, V., Asturias, S., Pena, L., Connor, D. B. O., Luc, A. R., Russo, A. A., Ruzzenente, A., Taddei, A., Cona, C., Bottini, C., Pascale, G., Rotunno, G., Solaini, L., Pascale, M. M., Notarnicola, M., Corbellino, M., Sacco, M., Ubiali, P., Cautiero, R., Bocchetti, T., Muzio, E., Guglielmo, V., Morandi, E., Mao, P., de Luca, E., Ali, F. M., Strupas, K., Kondrotas, P., Baltrunas, R., Kutkevicius, J., Ignatavicius, P., Tan, C. L., Siaw, J. Y., Yam, S. Y., Wilson, L., Aziz, M. R. A., Bondin, J., Zorrilla, C. D., Majbar, A., Sale, D., Abdullahi, L., Osagie, O., Faboya, O., Fatuga, A., Taiwo, A., Nwabuoku, E., Bliksoen, M., Khan, Z. A., Coronel, J., Miranda, C., Vasquez, I., Helguero-Santin, L. 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B., Pardo, G., HUS Abdominal Center, II kirurgian klinikka, Department of Anatomy, Pertti Panula / Principal Investigator, Clinicum, M Drake, Thoma, Pata, Francesco, Ghosh, Dhruv, O Ademuyiwa, Adesoji, Arnaud, Alexi, Bhangu, Aneel, Edward Fitzgerald, J, Glasbey, Jame, M Harrison, Ewen, Lorena Aguilera, Maria, Alexander, Philip, W Al-Saqqa, Sara, Borda-Luque, Giuliano, Costas-Chavarri, Ainhoa, Ntirenganya, Faustin, J Fergusson, Stuart, C Allen Ingabire, J, Ismaïl, Lawani, Khairy Salem, Hosni, Theophilus Teddy Kojo, Anyomih, Carmela Lapitan, Marie, Lilford, Richard, L Mihaljevic, Andre, Morton, Dion, Zeta Mutabazi, Alphonse, Nepogodiev, Dmitri, O Adisa, Adewale, Ots, Riinu, Pinkney, Thoma, Poškus, Toma, Uzair Qureshi, Ahmad, Ramos-De la Medina, Antonio, Rayne, Sarah, A Shaw, Catherine, Shu, Sebastian, Spence, Richard, Smart, Neil, Tabiri, Stephen, Verjee, Azmina, Runigamugabo, Emmy, Khatri, Chetan, Mohan, Midhun, Jaffry, Zahra, Altamini, Afnan, Kirby, Andrew, Soreide, Kjetil, Recinos, 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Ella, Irwin, Gareth, Stoddart, Michael, Kabariti, Rakan, Suresh, Sukrit, Gash, Katherine, Scott, Mark, Narayanan, Ragavan, Maimbo, Mayaba, Grizhja, Besmir, Ymeri, Shpetim, Galiqi, Gezim, Klappenbach, Roberto, Antezana, Diego, Enrique MendozaBeleño, Alvaro, Costa, Cecilia, Sanchez, Belen, Aviles, Susan, Gabriel Fermani, Claudio, Balmaceda, Rubén, Villalobos, Santiago, Manuel Carmona, Juan, Hamill, Daniel, Deutschmann, Peter, Sandler, Simone, Cox, Daniel, Nataraja, Ram, Sharpin, Claire, Ljuhar, Damir, Gray, Demi, Haines, Morgan, Iyer, Dush, Niranjan, Nithya, D'Amours, Scott, Ashtari, Morvarid, Franco, Helena, Rahman Mitul, Ashrarur, Karim, Sabbir, F Aman, Nowrin, Mahfuz Estee, Mahnuma, Salma, Umme, Razzaque, Joyeta, Hamidkanta, Tasnia, Tori, Sayeedaaktar, Shadid Alamin, Md, Roy, Swapnil, Shadid Al Amin, Md, Haque, Muhtarima, Faruq, Amreen, Iftekhar Margaret, Farhana, Padmore O'Shea, Greg, Jonnalagadda, Ramesh, Litvin, Andrey, Filatau, Aliaksandr, Paulouski, Dzmitry, Shubianok, Maryna, 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Mahmoud, Basma, Ali Mahmoud, Mohamed, Qenawy, Mostafa, M Rashed, Ahmed, Dahy, Ahmed, Sayed, Marwa, W Shamsedine, Ahmed, Mohamed, Bakeer, Hasan, Ahmad, M Saad, Mahmoud, Abdulbassit, Khalil, Khalidabdelatif, Nadia, Elzahed, Nada, Elkashash, Ahmed, Hafez, Sarah, Gad, Ahmed, Elkhadragy Maher, Mahmoud, Abdelsameea, Ahmed, Hafez, Mohamed, Sabe, Ahmad, Kalles, Vassili, Mohamed Bekheta, Nada, Ahmed, Ataa, Shahine, Ahmed, Dawood, Khaled, Gaafar, Shireen, Husseiny, Reem, Aboelmagd, Omnia, Soliman, Ahmed, Mesbah, Nourhan, Emadeldin, Hossam, Almeligy, Amgad, Hassan Bekhet, Amira, Hasan, Doaa, Alhady, Khaled, Khaled Sabe, Ahmad, A Elnajjar, Mahmoud, Aboelella, Majed, Hamsho, Ward, Hassan, Ihab, Saad, Hala, Abdelazim, Galaleldin, Mahmoud, Hend, Wael, Noha, M Kandil, Ahmedali, Magdy, Ahmed, Saidelkholy, Shimaa, Adel, Badreldineadel, Dabbour, Kareem, Elsherbiney, Saged, Mattar, Omar, Khaled Abdrabou, Abdulshafi, Yahia mohamedAly, Mohammed, Geuoshy, Abdelrahman, Elnagar, Ahmedglal, Ahmed, Saraibrahim, 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Nirumal, Milaksh, GohErn Tze, R, WahhabEusoffee WanAli, Syedabdul, Yee Gan, Yiing, Ron SwireTing, Jesse, S YSii, Samuel, Leong Koay, Kean, Koon Tan, Yi, EeZhiun Cheah, Alvin, Yee Wong, Chui, Nur'Azmah TuanMat, Tuan, Yern NeeChow, Crystal, Al Har, Prisca, Der, Yishan, Yong Tew, Yong, Henry, Fitjerald, Low, Xinwei, Theng Neo, Ya, Ee Heng, Hian, Ning Kong, Shu, Gan, Cheewei, Ting Mok, Yi, Wen Tan, Yee, Palayan, Kandasami, Devatata, Mahadevan, Jeng Cheong, Yih, Gunaseelan, Kuhaendran, NurulAin WanMohdNasir, Wan, Yoganathan, Pigeneswaren, Xian Lee, Eu, Er Saw, Jian, Jing Yeang, Li, Ying Koh, Pei, Yee Lim, Shyang, Yi Te, Shuang, Grech, Nicole, Magri, Daniela, Cassar, Kristina, Mizzi, Christine, Falzon, Malcolm, Shaikh, Nihaal, Scicluna, Ruth, Zammit, Stefan, Mizzi, Sean, Doris Brincat, Svetlana, Tembo, Thelma, ThanhHien Le, Vu, Grima, Tara, Sammut, Keith, Carabott, Kurt, Zarb, Ciskje, Navarro, Andre', Dimech, Thea, Camilleri, Georgettemarie, Bertuello, Isaac, Dalli, Jeffrey, Bonavia, Karl, 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Elena, Guglielmo, Vania, Morandi, Eugenio, Mao, Patrizio, De Luca, Emilia, Mahmoud Ali, Farah, Žilinskas, Justa, Strupas, Kestuti, Kondrotas, Pauliu, Baltrunas, Roberta, Kutkevicius, Juoza, Ignatavicius, Povila, Ling Tan, Choy, Yng Siaw, Jia, Young Yam, Sir, Wilson, Ling, Rezal Abdul Aziz, Mohamed, Bondin, John, Diaz Zorrilla, Carmina, Majbar, Ana, Sale, Danjuma, Abdullahi, Lawal, Osagie, Olabisi, Faboya, Omolara, Fatuga, Adedeji, Taiwo, Agboola, Nwabuoku, Emeka, Bliksøen, Marte, Ali Khan, Zain, Coronel, Jazmin, Miranda, Cesar, Vasquez, Idelso, M Helguero-Santin, Lui, Rickard, Jennifer, Adedeji, Adesina, Alqahtani, Saleh, Rath, Max, Van Niekerk, Michael, Zacharia Koto, Modise, Matos-Puig, Roel, Israelsson, Leif, Schuetz, Tobia, Arif Yuksek, Mahmut, Mericliler, Meric, Uluşahin, Mehmet, Wolf, Bernhard, Fairfield, Cameron, Liang Yong, Guo, Whitehurst, Katharine, Redgrave, Natalie, K Musyoka, Caroluce, Olivier, Jame, Lee, Kathryn, Cox, Michael, H Farhan-Alanie, Muhamed M, Callan, Rory, Chibuye, Chali, Hassanein Ahmed Ali, Tebian, Rekhis, Syrine, Rommaneh, Muna, Hao Sam, Zi, Lawani, Ismail, Brunelli Pugliesi, Thay, Pardo, Gabriel, Blanco, Ruth, and GlobalSurg Collaborative: Aneel Bhangu, Adesoji O Ademuyiwa, Maria Lorena Aguilera, Philip Alexander, Sara W Al-Saqqa, Giuliano Borda-Luque, Ainhoa Costas-Chavarri, Thomas M Drake, Faustin Ntirenganya, J Edward Fitzgerald, Stuart J Fergusson, James Glasbey, Jc Allen Ingabire, Lawani Ismaïl, Hosni Khairy Salem, Anyomih Theophilus Teddy Kojo, Marie Carmela Lapitan, Richard Lilford, Andre L Mihaljevic, Dion Morton, Alphonse Zeta Mutabazi, Dmitri Nepogodiev, Adewale O Adisa, Riinu Ots, Francesco Pata, Thomas Pinkney, Tomas Poškus, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Sarah Rayne, Catherine A Shaw, Sebastian Shu, Richard Spence, Neil Smart, Stephen Tabiri, Ewen M Harrison, Chetan Khatri, Midhun Mohan, Zahra Jaffry, Afnan Altamini, Andrew Kirby, Kjetil Søreide, Gustavo Recinos, Jen Cornick, Maria Marta Modolo, Dushyant Iyer, Sebastian King, Tom Arthur, Sayeda Nazmum Nahar, Ade Waterman, Michael Walsh, Arnav Agarwal, Augusto Zani, Mohammed Firdouse, Tyler Rouse, Qinyang Liu, Juan Camilo Correa, Peep Talving, Mengistu Worku, Alexis Arnaud, Vassilis Kalles, Basant Kumar, Sunil Kumar, Radhian Amandito, Roy Quek, Luca Ansaloni, Ahmed Altibi, Donatas Venskutonis, Justas Zilinskas, Tomas Poskus, John Whitaker, Vanessa Msosa, Yong Yong Tew, Alexia Farrugia, Elaine Borg, Zineb Bentounsi, Tanzeela Gala, Ibrahim Al-Slaibi, Haya Tahboub, Osaid H Alser, Diego Romani, Sebestian Shu, Piotr Major, Aurel Mironescu, Matei Bratu, Amar Kourdouli, Aliyu Ndajiwo, Abdulaziz Altwijri, Mohammed Ubaid Alsaggaf, Ahmad Gudal, Al Faifi Jubran, Sam Seisay, Bettina Lieske, Irene Ortega, Jenifa Jeyakumar, Kithsiri J Senanayake, Omar Abdulbagi, Yucel Cengiz, Dmitri Raptis, Yuksel Altinel, Chia Kong, Ella Teasdale, Gareth Irwin, Michael Stoddart, Rakan Kabariti, Sukrit Suresh, Katherine Gash, Ragavan Narayanan, Mayaba Maimbo, Besmir Grizhja, Shpetim Ymeri, Gezim Galiqi, Roberto Klappenbach, Diego Antezana, Alvaro Enrique Mendoza Beleño, Cecilia Costa, Belen Sanchez, Susan Aviles, Claudio Gabriel Fermani, Rubén Balmaceda, Santiago Villalobos, Juan Manuel Carmona, Daniel Hamill, Peter Deutschmann, Simone Sandler, Daniel Cox, Ram Nataraja, Claire Sharpin, Damir Ljuhar, Demi Gray, Morgan Haines, Dush Iyer, Nithya Niranjan, Scott D'Amours, Morvarid Ashtari, Helena Franco, Ashrarur Rahman Mitul, Sabbir Karim, Nowrin F Aman, Mahnuma Mahfuz Estee, Umme Salma, Joyeta Razzaque, Tasnia Hamid Kanta, Sayeeda Aktar Tori, Shadid Alamin, Swapnil Roy, Shadid Al Amin, Rezaul Karim, Muhtarima Haque, Amreen Faruq, Farhana Iftekhar, Margaret O'Shea, Greg Padmore, Ramesh Jonnalagadda, Andrey Litvin, Aliaksandr Filatau, Dzmitry Paulouski, Maryna Shubianok, Tatsiana Shachykava, Dzianis Khokha, Vladimir Khokha, Fernande Djivoh, Francis Dossou, Djifid Morel Seto, Dansou Gaspard Gbessi, Bruno Noukpozounkou, Yacoubou Imorou 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Elgheriany, Eman Abdelmageed, Eman Abd Al Raouf, Esraa Samir Elbanby, Maha Elmasry, Mahitab Morsy Farahat, Eman Yahya Mansor, Eman Magdy Hegazy, Esraa Gamal, Heba Gamal, Hend Kandil, Doaa Maher Abdelrouf, Mohamed Moaty, Dina Gamal, Nada El-Sagheer, Mohamed Salah, Salma Magdy, Asmaa Salah, Ahmed Essam, Ahmed Ali, Mahmoud Badawy, Sara Ahmed, Mazed Mohamed, Abdelrahman Assal, Mohamed Sleem, Mai Ebidy, Aly Abd-Elrazek, Diaaaldin Zahran, Nourhan Adam, Mohamed Nazir, Adel B Hassanein, Ahmed Ismail, Amira Elsawy, Rana Mamdouh, Mohamed Mabrouk, Lopna Ahmed Mohamed Ahmed, Mohamed Hassab Alnaby, Eman Magdy, Manar Abd-Elmawla, Marwan Fahim, Bassant Mowafy, Moustafa Ibrahim Mahmoud, Meran Allam, Muhammad Alkelani, Noran Halim El Gendy, Mariam Saad Aboul-Naga, Reham Alaa El-Din, Alyaa Halim Elgendy, Mohamed Ismail, Mahmoud Shalaby, Aya Adel Elsharkawy, Mahmoud Elsayed Moghazy, Khaled Hesham Elbisomy, Hend Abdel Gawad Shakshouk, Mohamed Fouad Hamed, Mai Mohamed Ebidy, Mostafa Abdelkader, Mohamed Karkeet, Hayam Ahmed, Israa Adel, Mohammad Elsayed Omar, Mohamed Ibrahim, Omar Ghoneim, Omar Hesham, Shimaa Gamal, Karim Hilal, Omar Arafa, Sawsan Adel Awad, Menatalla Salem, Fawzia Abdellatif Elsherif, Nourhan Elsabbagh, Moustafa R Aboelsoud, Ahmed Hossam Eldin Fouad Rida, Amr Hossameldin, Ethar Hany, Yomna Hosny Asar, Nourhan Anwar, Mohamed Gadelkarim, Samar Abdelhady, Eman Mohamed Morshedy, Reham Saad, Nourhan Soliman, Mahmoud Salama, Eslam Ezzat, Arwa Mohamed, Arwa Ibrahim, Alaa Fergany, Sara Mohammed, Aya Reda, Yomna Allam, Hanan Adel Saad, Afnan Abdelfatah, Aya Mohamed Fathy, Ahmed El-Sehily, Esraa Abdalmageed Kasem, Ahmed Tarek Abdelbaset Hassan, Ahmed Rabeih Mohammed, Abdalla Gamal Saad, Yasmin Elfouly, Nesma Elfouly, Arij Ibrahim, Amr Hassaan, Mohammed Mustafa Mohammed, Ghada Elhoseny, Mohamed Magdy, Esraa Abd Elkhalek, Yehia Zakaria, Tarek Ezzat, Ali Abo El Dahab, Mohamed Kelany, Sara Arafa, Osama Mokhtar Mohamed Hassan, Nermin Mohamed Badwi, Ahmad Saber Sleem, Hussien Ahmed, Kholoud Abdelbadeai, Mohamed Abozed Abdullah, Muhammad Amsyar Auni Lokman, Suraya Bahar, Anan Rady Abdelazeam, Abdelrahman Adelshone, Muhammad Bin Hasnan, Athirah Zulkifli, Siti Nur Alia Kamarulzamil, Abdelaziz Elhendawy, Aliang Latif, Ahmad Bin Adnan, Shahadatul Shaharuddin, Aminah Hanum Haji Abdul Majid, Mahmoud Amreia, Dina Al-Marakby, Mahmoud Salma, Mohamad Jeffrey Bin Ismail, Elissa Rifhan Mohd Basir, Citra Dewi Mohd Ali, Aya Yehia Ata, Maha Nasr, Asmaa Rezq, Ahmed Sheta, Sherif Tariq, Abd Elkhalek Sallam, Abdelrhman Kz Darwish, Sohaila Elmihy, Shady Elhadry, Ahmed Farag, Haidar Hajeh, Abdelaziz Abdelaal, Amro Aglan, Ahmed Zohair, Mahitab Essam, Omar Moussa, Esraa El-Gizawy, Mostafa Samy, Safia Ali, Esraa El Halawany, Ahmed Ata, Mohamed El Halawany, Mohamed Nashat, Samar Soliman, Alaa Elazab, Mostada Samy, Mohamed A Abdelaziz, Khaled Ibrahim, Ahmed Mohamed Ibrahim, Ammar Gado, Usama Hantour, Esraa Alm Eldeen, Mohamed Reda Loaloa, Arwa Abouzaid, Mostafa Ahmed Bahaa Eldin, Eman Hashad, Fathy Sroor, Doaa Gamil, Eman Mahmoud Abdulhakeem, Mahmoud Zakaria, Fawzy Mohamed, Marwan Abubakr, Elsayed Ali, Hesham Magdy, Menna Tallah Ramadan, Mohamed Abdelaty Mohamed, Salma Mansour, Hager Abdul Aziz Amin, Ahmed Rabie Mohamed, Mahmoud Saami, Nada Ahmed Reda Elsayed, Adham Tarek, Sabry Mohy Eldeen Mahmoud, Islam Magdy El Sayed, Amira Reda, Martina Yusuf Shawky, Mohammed Mousa Salem, Shahinaz Alaa El-Din, Noha Abdullah Soliman, Muhammed Talaat, Shahinaz Alaael-Dein, Ahmed Abd Elmoen Elhusseiny, Noha Abdullah, Mohammed Elshaar, Aya Abdelfatah Ibraheem, Hager Abdulaziz, Mohammed Kamal Ismail, Mona Hamdy Madkor, Mohamed Abdelaty, Sara Mahmoud Abdel-Kader, Osama Mohamed Salah, Mahmoud Eldafrawy, Ahmed Zaki Eldeeb, Mostafa Mahmoud Eid, Attia Attia, Khalid Salah El-Dien, Ayman Shwky, Mohamed Adel Badenjki, Abdelrahman Soliman, Samaa Mahmoud Al Attar, Farrag Sayed, Fahd Abdel Sabour, Mohammed G Azizeldine, Muhammad Shawqi, Abdullah Hashim, Ahmed Aamer, Ahmed Mahmoud Abdelraouf, 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Ahmed Saleh, Hesham Mohammed Bakry, Manar Saeed, Shady Mahmoud, Badreldin Adel Tawfik, Samar Adel Ismail, Esraay Zakaria, Mariam O Gad, Mohamed Salah Elhelbawy, Monica Bassem, Noha Maraie, Nourhan Medhat Elhadary, Nourhan Semeda, Shaza Rabie Mohamed, Hesham Mohammed Bakry, A A Essam, Dina Tarek, Khlood Ashour, Alaa Elhadad, Abdulrahman Abdel-Aty, Ibrahim Rakha, Sara Mamdouh Matter, Rasha Abdelhamed, Omar Abdelkader, Ayat Hassaan, Yasmin Soliman, Amna Mohamed, Sara Ghanem, Sara Amr Mohamed Farouk, Eman Mohamed Ibrahim, Esraa El-Taher, Merna Mostafa, Mohamed Fawzy Mahrous Badr, Rofida Elsemelawy, Aya El-Sawy, Ahmad Bakr, Ahmad Abdel Razaq Al Rafati, Sten Saar, Arvo Reinsoo, Nebyou Seyoum, Tewodros Worku, Agazi Fitsum, Matti Tolonen, Ari Leppäniemi, Ville Sallinen, Benogreît Parmentier, Matthieu Peycelon, Sabine Irtan, Sabrina Dardenne, Elsa Robert, Betty Maillot, Etienne Courboin, Alexis Pierre Arnaud, Juliette Hascoet, Olivier Abbo, Amir Ait Kaci, Thomas Prudhomme, Quentin Ballouhey, 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Antanas Zadoroznas, Nerijus Kaselis, Greta Žiubrytė, Finaritra Casimir Fleur Prudence Rahantasoa, Luc Hervé Samison, Fanjandrainy Rasoaherinomenjanahary, Todisoa Emmanuella Christina Tolotra, Cornelius Mukuzunga, Chimwemwe Kwatiwani, Nelson Msiska, Feng Yih Chai, Siti Mohd Desa Asilah, Khuzaimah Zahid Syibrah, Pui Xin Chin, Afizah Salleh, Nur Zulaika Riswan, April Camilla Roslani, Hoong-Yin Chong, Nora Abdul Aziz, Keat-Seong Poh, Chu-Ann Chai, Sandip Kumar, Mustafa Mohammed Taher, Nik Ritza Kosai, Dayang Nita Abdul Aziz, Reynu Rajan, Rokayah Julaihi, Durvesh Lacthman Jethwani, Muhammad Taqiyuddin Yahaya, Nik Azim Nik Abdullah, Susan Wndy Mathew, Kuet Jun Chung, Milaksh Kumar Nirumal, R Goh Ern Tze, Syed Abdul Wahhab Eusoffee Wan Ali, Yiing Yee Gan, Jesse Ron Swire Ting, Samuel S Y Sii, Kean Leong Koay, Yi Koon Tan, Alvin Ee Zhiun Cheah, Chui Yee Wong, Tuan Nur'Azmah Tuan Mat, Crystal Yern Nee Chow, Prisca Al Har, Yishan Der, Fitjerald Henry, Xinwei Low, Ya Theng Neo, Hian Ee Heng, Shu 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Shaheen, Azher Herebat, Aram Abdelhaq, Ahmad Shalabi, Maram Abu-Toyour, Fatema Asi, Ala Shamasneh, Anwar Atiyeh, Mousa Mustafa, Rula Zaa'treh, Majd Dabboor, Enas Alaloul, Heba Baraka, Jehad Meqbil, Alaa Al-Buhaisi, Mohamedraed Elshami, Samah Afana, Sahar Jaber, Said Alyacoubi, Yousef Abuowda, Tasneem Idress, Eman Abuqwaider, Sara Al-Saqqa, Alaa Bowabsak, Alaa El Jamassi, Doaa Hasanain, Hadeel Al-Farram, Maram Salah, Aya Firwana, Marwa Hamdan, Israa Awad, Ahmad Ashour, Fayez Elian Al Barrawi, Ahmed Alkhatib, Maha Al-Faqawi, Mohamed Fares, Amjad Elmashala, Mohammad Adawi, Ihdaa Adawi, Reem Khreishi, Rose Khreishi, Ahmad Ashour, Ahed Ghaben, Gustavo Miguel Machain Vega, Jorge Torres Cardozo, Marcelo O'Higgins Roche, Gustavo Rodolfo Pertersen Servin, Helmut Alfredo Segovia Lohse, Larissa Ines Páez Lopez, Ramón Augusto Melo Cardozo, Fernando Espinoza, Angel David Pérez Rojas, Diana Sanchez, Camila Sanchez Samaniego, Shalon Guevara Torres, Alexander Canta Calua, Cesar Razuri, Nadia Ortiz, Xianelle Rodriguez, Nahilia Carrasco, Fridiz Saravia, Hector Shibao Miyasato, María Valcarcel-Saldaña, Ysabel Esthefany Alejos Bermúdez, Juan Carpio, Walter Ruiz Panez, Pedro Angel Toribio Orbegozo, Carolina Guzmán Dueñas, Kevin Turpo Espinoza, Ana Maria Sandoval Barrantes, Jorge Armando Chungui Bravo, Lorena Fuentes-Rivera, Carmen Fernández, Bárbara Málaga, Joselyn Ye, Ricardo Velasquez, Jannin Salcedo, Ana Lucia Contreras-Vergara, Angelica Genoveva Vergara Mejia, Maria Soledad Gonzales Montejo, Marilia Del Carmen Escalante Salas, Willy Alcca Ticona, Marvin Vargas, George Christian Manrique Sila, Robinson Mas, Arazzelly Del Pilar Paucar, Armando José Román Velásquez, Alina Robledo-Rabanal, Ludwing Alexander Zeta Solis, Kenny Turpo Espinoza, José Luis Hamasaki Hamaguchi, Erick Samuel Florez Farfan, Linda Alvi Madrid Barrientos, Juan Jaime Herrera Matta, John Jemuel V Mora, Menold Archee P Redota, Manuel Francisco Roxas, Maria Jesusa B Maño, Marie Dione Parreno-Sacdalan, Christel Leanne Almanon, Maciej Walędziak, Rafał Roszkowski, Michał Janik, Anna Lasek, Dorota Radkowiak, Mateusz Rubinkiewicz, Cristina Fernandes, Jose Costa-Maia, Renato Melo, Liviu Muntean, Aurel Sandu Mironescu, Lucian Corneliu Vida, Mariuca Popa, Hogea Mircea, Mihaela Vartic, Bogdan Diaconescu, Matei Razvan Bratu, Ionut Negoi, Mircea Beuran, Cezar Ciubotaru, Norbert Uzabumwana, Dieudonne Duhoranenayo, Elio Jovine, Nicola Zanini, Giovanni Landolfo, Murad Aljiffry, Faisal Idris, Mohammed Saleh A Alghamdi, Ashraf Maghrabi, Abdulmalik Altaf, Aroub Alkaaki, Ahmad Khoja, Abrar Nawawi, Sondos Turkustani, Eyad Khalifah, Adel Albiety, Sarah Sahel, Reham Alshareef, Mohammed Najjar, Ahmed Alzahrani, Ahmed Alghamdi, Wedyan Alhazmi, Ghiath Al Saied, Mohammed Alamoudi, Muhammed Masood Riaz, Mazen Hassanain, Basmah Alhassan, Abdullah Altamimi, Reem Alyahya, Norah Al Subaie, Fatema Al Bastawis, Afnan Altamimi, Thamer Nouh, Roaa Khan, Milan Radojkovic, Ljiljana Jeremic, Milica Nestorovic, Jia Hao Law, Keith Say Kwang Tan, Ryan Choon Kiat Tan, Joel Kin Tan, Lau Wen Liang Joel, Xue Wei Chan, Faith Qi Hui Leong, Choon Seng Chong, Sharon Koh, Kai Yin Lee, Kuok Chung Lee, Kent Pluke, Britta Dedekind, Puyearashid Nashidengo, Mark Ian Hampton, Johanna Joosten, Sanju Sobnach, Liana Roodt, Anthony Sander, James Pape, Niveshni Maistry, Phumudzo Ndwambi, Kamau Kinandu, Myint Tun, Frederick Du Toit, Quinn Ellison, Sule Burger, D C Grobler, Lawrence Bongani Khulu, Rachel Moore, Vicky Jennings, Astrid Leusink, Nazmie Kariem, Juan Gouws, Kathryn Chu, Heather Bougard, Fazlin Noor, Angela Dell, Stephanie Van Straten, Arvin Khamajeet, Serge Kapenda Tshisola, Kalangu Kabongo, Victor Kong, Yoshan Moodley, Frank Anderson, Thandinkosi Madiba, Flip du Plooy, Leila Hartford, Gareth Chilton, Parveen Karjiker, Matlou Ernest Mabitsela, Sibongile Ruth Ndlovu, Maria Badicel, Robert Jaich, Jaime Ruiz-Tovar, Luis Garcia-Florez, Jorge L Otero-Díez, Virginia Ramos Pérez, Nuria Aguado Suárez, Javier Minguez García, Sara Corral Moreno, Maria Vicenta Collado, Virginia Jiménez Carneros, Javier García Septiem, Mariana Gonzalez, Antonio Picardo, Enrique Esteban, Esther Ferrero, Eloy Espin-Basany, Ruth Blanco-Colino, Valeria Andriola, Lorena Solar García, Elisa Contreras, Carmen García Bernardo, Janet Pagnozzi, Sandra Sanz, Alberto Miyar de León, Asnel Dorismé, Joseluis Rodicio, Aida Suarez, Jessica Stuva, Tamara Diaz Vico, Laura Fernandez-Vega, Carla Soldevila-Verdeguer, Fatima Sena-Ruiz, Natalia Pujol-Cano, Paula Diaz-Jover, José Maria Garcia-Perez, Juan Jose Segura-Sampedro, Cristina Pineño-Flores, David Ambrona-Zafra, Andrea Craus-Miguel, Patricia Jimenez-Morillas, Angela Mazzella, A B Jayathilake, Spb Thalgaspitiya, L S Wijayarathna, Pmsn Wimalge, Hakeem Ayomi Sanni, Ogheneochuko Okenabirhie, Anmar Homeida, Abobaker Younis, Omer Abdelbagi Omer, Mustafa Abdulaziz, Ali Mussad, Ali Adam, Ida Björklund, Sandra Ahlqvist, Anders Thorell, Fredrik Wogensen, Arestis Sokratous, Michaela Breistrand, Hildur Thorarinsdottir, Johanna Sigurdadottir, Maziar Nikberg, Abbas Chabok, Maria Hjertberg, Peter Elbe, Deborah Saraste, Wiktor Rutkowski, Louise Forlin, Karoliina Niska, Malin Sund, Dennis Oswald, Georgios Peros, Rafael Bluelle, Katharina Reinisch, Daniel Frey, Adrian Palma, Dimitri Aristotle Raptis, Lucius Zumbühl, Markus Zuber, Roger Schmid, Gabriela Werder, Antonio Nocito, Alexandra Gerosa, Silke Mahanty, Lukas Werner Widmer, Julia Müller, Alissa Gübeli, Grzegorz Zuk, Osman Bilgin Gulcicek, Talar Vartanoglu, Emin Kose, Servet Rustu Karahan, Mehmet Can Aydin, Nuri Alper Sahbaz, Ilkay Halicioglu, Halil Alis, Ipek Sapci, Can Adiyaman, Ahmet Murat Pektaş, Turgut Bora Cengiz, Ilkan Tansoker, Vedatcan Işler, Muazzez Cevik, Deniz Mutlu, Volkan Ozben, Berk Baris Ozmen, Sefa Bayram, Sinem Yolcu, Berna Buse Kobal, Ömer Faruk Toto, Haluk Cem Çakaloğlu, Kagan Karabulut, Vahit Mutlu, Bahar Busra Ozkan, Saban Celik, Anil Semiz, Selim Bodur, Enisburak Gül, Busra Murutoglu, Reyyan Yildirim, Bahadir Emre Baki, Ekin Arslan, Mehmet Ulusahin, Ali Guner, Kudir Tomas, Nathan Walker, Nikhita Shrimanker, Simon Cole, Ryan Breslin, Ravi Srinivasan, Mohamed Elshaer, Kristina Hunter, Ahmed Al-Bahrani, Ignatius Liew, Nora Grace Mairs, Alistair Rocke, Lachlan Dick, Mobeen Qureshi, Debkumar Chowdhury, Naomi Wright, Clare Skerritt, Dorothy Kufeji, Adrienne Ho, Tharindra Dissanayake, Athula Tennakoon, Wadah Ali, Shujing Jane Lim, Charlene Tan, Stephen O'Neill, Catrin Jones, Stephen Knight, Dima Nassif, Abhishek Sharma, Oliver Warren, Rebecca White, Aia Mehdi, Nathan Post, Eliana Kalakouti, Enkhbat Dashnyam, Frederick Stourton, Ioannis Mykoniatis, Chelise Currow, Francisca Wong, Ashish Gupta, Veeranna Shatkar, Joshua Luck, Suraj Kadiwar, Alexander Smedley, Rebecca Wakefield, Philip Herrod, James Blackwell, Jonathan Lund, Fraser Cohen, Ashwath Bandi, Stefano Giuliani, Giles Bond-Smith, Theodore Pezas, Neda Farhangmehr, Tomas Urbonas, Miklos Perenyei, Philip Ireland, Natalie Blencowe, Kirk Bowling, David Bunting, Lydia Longstaff, Kenneth Keogh, Hyunjin Jeon, Muhammad Rafaih Iqbal, Shivun Khosla, Anna Jeffery, James Perera, Ahmad Aboelkassem Ibrahem, Tariq Alhammali, Yahya Salama, Shaun Oram, Thomas Kidd, Fraser Cullen, Christopher Owen, Michael Wilson, Seehui Chiu, Hannah Sarafilovic, Jennifer Ploski, Elizabeth Evans, Athar Abbas, Sylvia Kamya, Norzawani Ishak, Carly Bisset, Cedar Andress, Ye Ru Chin, Priya Patel, David Evans, Aidan Haslegrave, Adam Boggon, Kirsten Laurie, Katie Connor, Thomas Mann, Anahita Mansuri, Rachel Davies, Ewen Griffiths, Aized Raza Shahbaz, Calvin Eng, Farhat Din, Ariadne L'Heveder, Esther Hg Park, Ramanish Ravishankar, Kirsten McIntosh, Jih Dar Yau, Luke Chan, Susan McGarvie, Lingshan Tang, Hui Lim, Suhhuey Yap, Jay Park, Zhan Herr Ng, Shahrukh Mirza, Yun Lin Ang, Luke Walls, Chloe Roy, Simon Paterson-Brown, Julian Camilleri-Brennan, Kenneth Mclean, Michelle S D'Souza, Savva Pronin, David Ewart Henshall, Eunice Zuling Ter, Dina Fouad, Ashish Minocha, William English, Catrin Morgan, Dominic Townsend, Laura Maciejec, Shareef Mahdi, Onyinye Akpenyi, Elisabeth Hall, Hanaan Caydiid, Zakaria Rob, Tom Abbott, Hew D Torrance, Robin Johnston, Mohammed Aki Gani, Gianpiero Gravante, Shivanchan Rajmohan, Kiran Majid, Shiva Dindyal, Christopher Smith, Madanmohan Palliyil, Sanjay Patel, Luke Nicholson, Neil Harvey, Katie Baillie, Sam Shillito, Suzanne Kershaw, Rebecca Bamford, Peter Orton, Elke Reunis, Robert Tyler, Wai Cheong Soon, Guled M Jama, Dharminder Dhillon, Khyati Patel, Shayanthan Nanthakumaran, Rachel Heard, Kar Yan Chen, Behrad Barmayehvar, Uttaran Datta, Sivesh K Kamarajah, Sharad Karandikar, Sobhana Iftekhar Tani, Eimear Monaghan, Philippa Donnelly, Michael Walker, Jehangirshaw Parakh, Sarah Blacker, Anil Kaul, Arjun Paramasivan, Sameh Farag, Ashrafun Nessa, Salwa Awadallah, Jieqi Lim, James Chean Khun Ng, Ravi P Kiran, Alice Murray, Eric Etchill, Mohini Dasari, Juan Puyana, Nadeem Haddad, Martin Zielinski, Asad Choudhry, Celeste Caliman, Mieshia Beamon, Therese Duane, Mamta Swaroop, Jonathan Myers, Rebecca Deal, Erik Schadde, Mark Hemmila, Lena Napolitano, Kathleen To, Alex Makupe, Joseph Musowoya, Niels van der Naald, Dayson Kumwenda, Alex Reece-Smith, Kars Otten, Anna Verbeek, Marloes Prins, Alibeth Andres Baquero Suarez, Ruben Balmaceda, Chelsea Deane, Emilio Dijan, Mahmoud Elfiky, Laura Koskenvuo, Aurore Thollot, Bernard Limoges, Carmen Capito, Challine Alexandre, Henri Kotobi, Julien Leroux, Kalitha Pinnagoda, Nicolas Henric, Olivier Azzis, Olivier Rosello, Poddevin Francois, Sara Etienne, Philippe Buisson, Sophian Hmila, Joe-Nat Clegg-Lamptey, Osman Imoro, Owusu Emmanuel Abem, Dimitrios Papageorgiou, Vasiliki Soulou, Sabrina Asturias, Lenin Peña, Donal B O'Connor, Alberto Realis Luc, Alfio Alessandro Russo, Andrea Ruzzenente, Antonio Taddei, Camilla Cona, Corrado Bottini, Giovanni Pascale, Giuseppe Rotunno, Leonardo Solaini, Marco Maria Pascale, Margherita Notarnicola, Mario Corbellino, Michele Sacco, Paolo Ubiali, Roberto Cautiero, Tommaso Bocchetti, Elena Muzio, Vania Guglielmo, Eugenio Morandi, Patrizio Mao, Emilia de Luca, Farah Mahmoud Ali, Justas Žilinskas, Kestutis Strupas, Paulius Kondrotas, Robertas Baltrunas, Juozas Kutkevicius, Povilas Ignatavicius, Choy Ling Tan, Jia Yng Siaw, Sir Young Yam, Ling Wilson, Mohamed Rezal Abdul Aziz, John Bondin, Carmina Diaz Zorrilla, Anass Majbar, Danjuma Sale, Lawal Abdullahi, Olabisi Osagie, Omolara Faboya, Adedeji Fatuga, Agboola Taiwo, Emeka Nwabuoku, Marte Bliksøen, Zain Ali Khan, Jazmin Coronel, Cesar Miranda, Idelso Vasquez, Luis M Helguero-Santin, Jennifer Rickard, Adesina Adedeji, Saleh Alqahtani, Max Rath, Michael Van Niekerk, Modise Zacharia Koto, Roel Matos-Puig, Leif Israelsson, Tobias Schuetz, Mahmut Arif Yuksek, Meric Mericliler, Mehmet Ulusahin, Bernhard Wolf, Cameron Fairfield, Guo Liang Yong, Katharine Whitehurst, Natalie Redgrave, Caroluce K Musyoka, James Olivier, Kathryn Lee, Michael Cox, Muhamed M H Farhan-Alanie, Rory Callan, Chali Chibuye, Tebian Hassanein Ahmed Ali, Syrine Rekhis, Muna Rommaneh, Zi Hao Sam, Thays Brunelli Pugliesi, Gabriel Pardo, Ruth Blanco
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Male ,paediatric ,Cohort Studies ,0302 clinical medicine ,Primary outcome ,gastro-enterologic surgery ,Risk Factors ,Prospective Studies ,030212 general & internal medicine ,paediatrics ,Prospective cohort study ,Child ,Digestive System Surgical Procedures ,Original Research ,lcsh:R5-920 ,Paediatric surgery ,Health Policy ,Human development (humanity) ,3142 Public health care science, environmental and occupational health ,3. Good health ,CONGENITAL-ANOMALIES ,030220 oncology & carcinogenesis ,Child, Preschool ,surgical infection ,Female ,lcsh:Medicine (General) ,Surgical site infection ,Cohort study ,Human ,AFRICA ,medicine.medical_specialty ,CARE-ASSOCIATED INFECTION ,Adolescent ,lcsh:Infectious and parasitic diseases ,NO ,03 medical and health sciences ,MIDDLE-INCOME COUNTRIES ,medicine ,Humans ,Surgical Wound Infection ,lcsh:RC109-216 ,In patient ,Human Development Index ,business.industry ,Kirurgi ,Risk Factor ,Public Health, Environmental and Occupational Health ,Infant, Newborn ,Infant ,Digestive System Surgical Procedure ,GLOBAL BURDEN ,3126 Surgery, anesthesiology, intensive care, radiology ,Surgery ,Prospective Studie ,Cohort Studie ,business - Abstract
Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p
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- 2020
23. [GABA.sub.B] receptors and glucose homeostasis: evaluation in [GABA.sub.B] receptor knockout mice
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Bonaventura, M.M., Catalano, P.N., Chamson-Reig, A., Arany, E., Hill, D., Bettler, B., Saravia, F., Libertun, C., and Lux-Lantos, V.A.
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Homeostasis -- Evaluation ,Genetically modified mice -- Physiological aspects ,Insulin -- Properties ,Pancreas -- Properties ,Histology -- Research ,Biological sciences - Abstract
GABA has been proposed to inhibit insulin secretion through [GABA.sub.B] receptors ([GABA.sub.B]Rs) in pancreatic [beta]-cells. We investigated whether [GABA.sub.B]Rs participated in the regulation of glucose homeostasis in vivo. The animals used in this study were adult male and female BALB/C mice, mice deficient in the [GABA.sub.B1] subunit of the [GABA.sub.B]R ([GABA.sub.B.sup.-/-]), and wild types (WT). Blood glucose was measured under fasting/fed conditions and in glucose tolerance tests (GTTs) with a Lifescan Glucose meter, and serum insulin was measured by ELISA. Pancreatic insulin content and islet insulin were released by RIA. Western blots for the [GABA.sub.B1] subunit in islet membranes and immunohistochemistry for insulin and [GABA.sub.B1] were performed in both genotypes. BALB/C mice preinjected with Baclofen ([GABA.sub.B]R agonist, 7.5 mg/kg ip) presented impaired GTTs and decreased insulin secretion compared with saline-preinjected controls. [GABA.sub.B.sup.-/-] mice showed fasting and fed glucose levels similar to WT. [GABA.sub.B.sup.-/-] mice showed improved GTTs at moderate glucose overloads (2 g/kg). Baclofen pretreatment did not modify GTTs in [GABA.sub.B.sup.-/-] mice, whereas it impaired normal glycemia reinstatement in WT. Baclofen inhibited glucose-stimulated insulin secretion in WT isolated islets but was without effect in [GABA.sub.B.sup.-/-] islets. In [GABA.sub.B.sup.-/-] males, pancreatic insulin content was increased, basal and glucose-stimulated insulin secretion were augmented, and impaired insulin tolerance test and increased homeostatic model assessment of insulin resistance index were determined. Immunohistochemistry for insulin demonstrated an increase of very large islets in [GABA.sub.B.sup.-/-] males. Results demonstrate that [GABA.sub.B]Rs are involved in the regulation of glucose homeostasis in vivo and that the constitutive absence of [GABA.sub.B]Rs induces alterations in pancreatic histology, physiology, and insulin resistance. [gamma]-aminobutyric acid; insulin; glycemia; pancreas histology
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- 2008
24. Post-thaw viability of bull AI-doses with low-sperm numbers
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Ballester, J., Johannisson, A., Saravia, F., Håård, M., Gustafsson, H., Bajramovic, D., and Rodriguez-Martinez, H.
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- 2007
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25. Differences in boar sperm head shape and dimensions recorded by computer-assisted sperm morphometry are not related to chromatin integrity
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Saravia, F., Núñez-Martínez, I., Morán, J.M., Soler, C., Muriel, A., Rodríguez-Martínez, H., and Peña, F.J.
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- 2007
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26. The search for the Booroola (FecB) mutation
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Morrell, J.M., primary, Saravia, F., additional, van, Wienen M., additional, Rodriguez-Martinez, H., additional, and Wallgren, M., additional
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- 2020
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27. The physiological roles of the boar ejaculate
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Rodriguez-Martinez, H., primary, Kvist, U., additional, Saravia, F., additional, Wallgren, M., additional, Johannissono, A., additional, Sanz, L., additional, Pena, F.J., additional, Martinez, E.A., additional, Roca, J., additional, Vazquez, J.M., additional, and Calvete, J.J., additional
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- 2020
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28. Surgical site infection after gastrointestinal surgery in children: An international, multicentre, prospective cohort study
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Harrison, E.M. Drake, T.M. Ghosh, D. Ademuyiwa, A.O. Bhangu, A. Fitzgerald, J.E. Glasbey, J. Borda-Luque, G. Costas-Chavarri, A. Ntirenganya, F. Fergusson, S.J. Ingabire, J.C.A. Ismaïl, L. Lilford, R. Mihaljevic, A.L. Morton, D. Mutabazi, A.Z. Adisa, A.O. Ots, R. Pinkney, T. Poškus, T. Shaw, C.A. Verjee, A. Runigamugabo, E. Khatri, C. Mohan, M. Jaffry, Z. Altamini, A. Kirby, A. Soreide, K. Cornick, J. Iyer, D. King, S. Arthur, T. Nahar, S.N. Waterman, A. Lawini, I. Rouse, T. Correa, J.C. Salem, H.K. Worku, M. Arnaud, A. Kalles, V. Aguilera, M.L. Recinos, G. Quek, R. Altibi, A. Whitaker, J. Bent, Z. Al-Slaibi, I. Tahboub, H. Alser, O.H. Shu, S. Mironescu, A. Bratu, M. Altwijri, A. Alsaggaf, M.U. Jubran, A.F. Seisay, S. Jeyakumar, J. Senanayake, K. Abdulbagi, O. Raptis, D. Kong, C. Suresh, S. Scott, M. Grizhja, B. Ymeri, S. Galiqi, G. Klappenbach, R. Antezana, D. Beleño, A.E.M. Costa, C. Sanchez, B. Aviles, S. Modolo, M.M. Fermani, C.G. Balmaceda, R. Villalobos, S. Carmona, J.M. Hamill, D. Deutschmann, P. Sandler, S. Cox, D. Nataraja, R. Sharpin, C. Ljuhar, D. Gray, D. Haines, M. Iyer, D. Niranjan, N. D'Amours, S. Ashtari, M. Franco, H. Mitul, A.R. Karim, S. Aman, N.F. Estee, M.M. Salma, U. Razzaque, J. Hamidkanta, T. Tori, S. Alamin, Md.S. Roy, S. Al Amin, Md.S. Haque, M. Faruq, A. Iftekhar, F. O'Shea, M. Padmore, G. Jonnalagadda, R. Litvin, A. Filatau, A. Paulouski, D. Shubianok, M. Shachykava, T. Khokha, D. Khokha, V. Djivoh, F. Lawani, I. Dossou, F. Seto, D.M. Gbessi, D.G. Noukpozounkou, B. Souaibou, Y.I. Keke, K.R. Hodonou, F. Ahounou, E. Alihonou, T. Dénakpo, M. Ahlonsou, G. Bedada, A.G. Nsengiyumva, C. Kwizera, S. Barendegere, V. Choi, P. Stock, S. Jamal, L. Firdouse, M. Zani, A. Azzie, G. Kushwaha, S. Agarwal, A. Chen, T.-L. Yip, C. Montes, I. Zapata, F. Sierra, S. Lanau, M.I.V. Arango, M.C.M. Restrepo, I.M. Sierra, S. Giraldo, R.S.R. Mendozaarango, M. Domini, E. Karlo, R. Mihanovic, J. Youssef, M. Elfeki, H. Thabet, W. Sanad, A. Tawfik, G. Zaki, A. 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Janik, M. Lasek, A. Major, P. Radkowiak, D. Rubinkiewicz, M. Fernandes, C. Costa-Maia, J. Melo, R. Muntean, L. Mironescu, A.S. Vida, L.C. Kourdouli, A. Popa, M. Mircea, H. Vartic, M. Diaconescu, B. Bratu, M.R. Negoi, I. Beuran, M. Ciubotaru, C. Ingabire, J.C.A. Alphonse, M. Uzabumwana, N. Duhoranenayo, D. Jovine, E. Zanini, N. Landolfo, G. Aljiffry, M. Idris, F. Alghamdi, M.S.A. Maghrabi, A. Altaf, A. Khalifah, E. Gudal, A. Albiety, A. Alkaaki, A. Alshareef, R. Khoja, A. Nawawi, A. Najjar, M. Turkustani, S. Sahel, S. Alzahrani, A. Alghamdi, A. Alhazmi, W. Al Saied, G. Alamoudi, M. Riaz, M.M. Hassanain, M. Alhassan, B. Altamimi, A. Alyahya, R. Alsubaie, N. Albastawis, F. Altamimi, A. Nouh, T. Khan, R. Radojkovic, M. Jeremic, L. Nestorovic, M. Law, J.H. Tan, K.S.K. Tan, R.C.K. Tan, J.K. Joel, L.W.L. Lieske, B. Chan, X.W. Leong, F.Q.H. Chong, C.S. Koh, S. Lee, K.Y. Lee, K.C. Pluke, K. Dedekind, B. Nashidengo, P. Hampton, M.I. Joosten, J. Sobnach, S. Roodt, L. Sander, A. Pape, J. Spence, R. Maistry, N. Ndwambi, P. Kinandu, K. Tun, M. du Toit, F. Ellison, Q. Burger, S. Grobler, D.C. Khulu, L.B. Moore, R. Jennings, V. Leusink, A. Kariem, N. Gouws, J. Chu, K. Bougard, H. Noor, F. Dell, A. Rayne, S. van Straten, S. Khamajeet, A. Tshisola, S.K. Kabongo, K. Kong, V. Moodley, Y. Anderson, F. Madiba, T. du Plooy, F. Hartford, L. Chilton, G. Karjiker, P. Mabitsela, M. Ndlovu, S. Badicel, M. Jaich, R. Ruiz-Tovar, J. Garcia-Florez, L. Otero-Diez, J.L. Ramosperez, V. Aguadosuarez, N. Garcia, J.M. Moreno, S.C. Collado, M.V. Carneros, V.J. Septiem, J.G. Gonzalez, M. Picardo, A. Esteban, E. Ferrero, E. Ortega, I. Espin-Basany, E. Blanco-Colino, R. Andriola, V. Lorena, I. Contreras, E. Garcíabernardo, C. Pagnozzi, J. Sanz, S. Miyardeleon, A. Dorismé, A. Rodicio, J. Suarez, A. Stuva, J. Diazvico, T. Fernandez-Vega, L. Soldevila-Verdeguer, C. Sena-Ruiz, F. Pujol-Cano, N. Diaz-Jover, P. Garcia-Perez, J.M. Segura-Sampedro, J.J. Pineño-Flores, C. Ambrona-Zafra, D. Craus-Miguel, A. Jimenez-Morillas, P. Mazzella, A. Jayathilake, A.B. Thalgaspitiya, S.P.B. Wijayarathna, L.S. Wimalge, P.M.S.N. Sanni, H.A. Ndajiwo, A. Okenabirhie, O. Homeida, A. Younis, A. Omer, O.A. Abdulaziz, M. Mussad, A. Gilani, A.M. Cengiz, Y. Björklund, I. Ahlqvist, S. Ahlqvist, S. Thorell, A. Wogensen, F. Sokratous, A. Breistrand, M. Thorarinsdottir, H. Sigurdadottir, J. Nikberg, M. Chabok, A. Hjertberg, M. Elbe, P. Saraste, D. Rutkowski, W. Forlin, L. Niska, K. Sund, M. Oswald, D. Peros, G. Bluelle, R. Reinisch, K. Frey, D. Palma, A. Raptis, D. Zumbühl, L. Zuber, M. Schmid, R. Werder, G. Nocito, A. Gerosa, A. Mahanty, S. Widmer, L.W. Müller, J. Gübeli, A. Zuk, G. Gulcicek, O.B. Altinel, Y. Vartanoglu, T. Kose, E. Karahan, S.R. Aydin, M.C. Sahbaz, N.A. Halicioglu, I. Alis, H. Sapci, I. Adiyaman, C. Pektaş, A.M. Cengiz, T.B. Tansoker, I. Işler, V. Cevik, M. Mutlu, D. Ozben, V. Ozmen, B.B. Bayram, S. Yolcu, S. Kobal, B.B. Toto, Ö.F. Çakaloğlu, H.C. Karabulut, K. Mutlu, V. Ozkan, B.B. Celik, S. Semiz, A. Bodur, S. Gül, E. Murutoglu, B. Yildirim, R. Baki, B.E. Arslan, E. Ulusahin, M. Guner, A. Walker, N. Shrimanker, N. Stoddart, M. Cole, S. Breslin, R. Srinivasan, R. Elshaer, M. Hunter, K. Al-Bahrani, A. Liew, I. Mairs, N.G. Rocke, A. Dick, L. Qureshi, M. Chowdhury, D. Wright, N. Skerritt, C. Ho, A. Dissanayake, T. Tennakoon, A. Ali, W. Lim, S.J. Tan, C. O'Neill, S. Jones, C. Knight, S. Nassif, D. Sharma, A. Warren, O. White, R. Mehdi, A. Post, N. Kalakouti, E. Dashnyam, E. Stourton, F. Mykoniatis, I. Currow, C. Wong, F. Gupta, A. Shatkar, V. Luck, J. Kadiwar, S. Smedley, A. Wakefield, R. Herrod, P. Blackwell, J. Lund, J. Cohen, F. Bandi, A. Giuliani, S. Bond-Smith, G. Pezas, T. Farhangmehr, N. Urbonas, T. Perenyei, M. Ireland, P. Blencowe, N. Bowling, K. Bunting, D. Longstaff, L. Smart, N. Keogh, K. Jeon, H. Iqbal, M.R. Khosla, S. Jeffery, A. Perera, J. Teasdale, E. Ibrahem, A.A. Alhammali, T. Salama, Y. Kabariti, R. Oram, S. Kidd, T. Cullen, F. Owen, C. Wilson, M. Chiu, S. Sarafilovic, H. Ploski, J. Evans, E. Abbas, A. Kamya, S. Ishak, N. Bisset, C. Andress, C. Chin, Y.R. Patel, P. Evans, D. Jeffery, A. Perera, J. Haslegrave, A. Boggon, A. Laurie, K. Connor, K. Mann, T. Nepogodiev, D. Mansuri, A. Davies, R. Griffiths, E. Shahbaz, A.R. Eng, C. Din, F. Heveder, A.L. Park, E.H.G. Ravishankar, R. McIntosh, K. Yau, J.D. Chan, L. McGarvie, S. Tang, L. Lim, H. Yap, S. Park, J. Ng, Z. Mirza, S. Ang, Y.L. Walls, L. Teasdale, E. Roy, C. Paterson-Brown, S. Camilleri-Brennan, J. McLean, K. D'Souza, M. Pronin, S. Henshall, D.E. Ter, E. Fouad, D. Minocha, A. English, W. Morgan, C. Townsend, D. Maciejec, L. Mahdi, S. Akpenyi, O. Hall, E. Caydiid, H. Rob, Z. Abbott, T. Torrance, H.D. Irwin, G. Johnston, R. Gani, M. Gravante, G. Rajmohan, S. Majid, K. Dindyal, S. Smith, C. Palliyil, M. Patel, S. Nicholson, L. Harvey, N. Baillie, K. Shillito, S. Kershaw, S. Bamford, R. Orton, P. Reunis, E. Tyler, R. Soon, W. Jama, G.M. Dhillon, D. Patel, K. Nanthakumaran, S. Heard, R. Chen, K.Y. Barmayehvar, B. Datta, U. Kamarajah, S.K. Iftekhartani, S. Monaghan, E. Donnelly, P. Walker, M. Parakh, J. Blacker, S. Kaul, A. Paramasivan, A. Farag, S. Nessa, A. Awadallah, S. Lim, J. Cheankhunng, J. Gash, K. Kiran, R.P. Murray, A. Etchill, E. Dasari, M. Puyana, J. Haddad, N. Zielinski, M. Choudhry, A. Caliman, C. Beamon, M. Duane, T. Narayanan, R. Swaroop, M. Myers, J. Deal, R. Schadde, E. Hemmila, M. Napolitano, L. To, K. Makupe, A. Musowoya, J. Maimbo, M. van der Naald, N. Kumwenda, D. Reece-Smith, A. Otten, K. Verbeek, A. Prins, M. Suarez, A.A.B. Balmaceda, R. Deane, C. Dijan, E. Elfiky, M. Koskenvuo, L. Thollot, A. Limoges, B. Capito, C. Alexandre, C. Kotobi, H. Leroux, J. Rod, J. Pinnagoda, K. Henric, N. Azzis, O. Rosello, O. Francois, P. Etienne, S. Buisson, P. Hmila, S. Clegg-Lamptey, J.-N. Imoro, O. Abem, O.E. Wondoh, P. Papageorgiou, D. Soulou, V. Asturias, S. Peña, L. Connor, D.B.O. Luc, A.R. Russo, A.A. Ruzzenente, A. Taddei, A. Cona, C. Bottini, C. Pascale, G. Rotunno, G. Solaini, L. Pascale, M.M. Notarnicola, M. Corbellino, M. Sacco, M. Ubiali, P. Cautiero, R. Bocchetti, T. Muzio, E. Guglielmo, V. Morandi, E. Mao, P. de Luca, E. Ali, F.M. Žilinskas, J. Strupas, K. Kondrotas, P. Baltrunas, R. Kutkevicius, J. Ignatavicius, P. Tan, C.L. Siaw, J.Y. Yam, S.Y. Wilson, L. Aziz, M.R.A. Bondin, J. Zorrilla, C.D. Majbar, A. Sale, D. Abdullahi, L. Osagie, O. Faboya, O. Fatuga, A. Taiwo, A. Nwabuoku, E. Bliksøen, M. Khan, Z.A. Coronel, J. Miranda, C. Vasquez, I. Helguero-Santin, L.M. Rickard, J. Adedeji, A. Alqahtani, S. Rath, M. van Niekerk, M. Koto, M.Z. Matos-Puig, R. Israelsson, L. Schuetz, T. Yuksek, M.A. Mericliler, M. Uluşahin, M. Wolf, B. Fairfield, C. Yong, G.L. Whitehurst, K. Wilson, M. Redgrave, N. Musyoka, C.K. Olivier, J. Lee, K. Cox, M. Farhan-Alanie, M.M.H. Callan, R. Chibuye, C. Ali, T.H.A. Rekhis, S. Rommaneh, M. Sam, Z.H. Lawani, I. Pugliesi, T.B. Pardo, G. GlobalSurg Collaborative
- Abstract
Introduction Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings. Methods A multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI). Results Of 1159 children across 181 hospitals in 51 countries, 523 (45·1%) children were from high HDI, 397 (34·2%) from middle HDI and 239 (20·6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12·8% (51/397) in middle HDI and 24·7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI. Conclusion The odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda. ©
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- 2020
29. Controlled cooling during semen cryopreservation does not induce capacitation of spermatozoa from two portions of the boar ejaculate
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Saravia, F., Hernández, M., Wallgren, M., Johannisson, A., and Rodríguez-Martínez, H.
- Published
- 2007
30. Effects of exposure of pre-pubertal boars to di(2-ethylhexyl) phthalate on their frozen-thawed sperm viability post-puberty
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Spjuth, L., Saravia, F., Johannisson, A., Lundeheim, N., and Rodríguez-Martínez, H.
- Published
- 2006
31. Abnormalities of the Hippocampus are Similar in Deoxycorticosterone Acetate-Salt Hypertensive Rats and Spontaneously Hypertensive Rats
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Pietranera, L., Saravia, F., Deniselle, M. C. Gonzalez, Roig, P., Lima, A., and De Nicola, A. F.
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- 2006
32. A new and simple method to evaluate early membrane changes in frozen–thawed boar spermatozoa
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PEÑA, F. J., SARAVIA, F., JOHANNISSON, A., WALGREN, M., and RODRÍGUEZ-MARTÍNEZ, H.
- Published
- 2005
33. Oestradiol Restores Cell Proliferation in Dentate Gyrus and Subventricular Zone of Streptozotocin-Diabetic Mice
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Saravia, F., Revsin, Y., Lux-Lantos, V., Beauquis, J., Homo-Delarche, F., and De Nicola, A. F.
- Published
- 2004
34. NOM-facilitated transport of metal ions in aquifers: importance of complex-dissociation kinetics and colloid formation
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Schmitt, D., Saravia, F., Frimmel, F.H., and Schuessler, W.
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- 2003
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35. 210 Horse allogeneic mesenchymal stem cells perform homing and ameliorate endometrial inflammation after induced endometritis of mares
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Navarrete, F., primary, Saravia, F., additional, Cisterna, G., additional, Rojas, F., additional, Rodríguez-Alvarez, L., additional, Rojas, D., additional, and Castro, F., additional
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- 2020
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36. Strategies to improve the fertility of frozen-thawed boar semen for artificial insemination
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Roca, J., primary, Rodriguez-Martinez, H., additional, Vazquez, J.M., additional, Bolarin, A., additional, Hernandez, M., additional, Saravia, F., additional, Wallgren, M., additional, and Martinez, E.A., additional
- Published
- 2019
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37. Chronic Diarrhea and Metabolic Acidosis Associated With Topiramate Use
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Gaby S. Gil, Noella Boma, Estuardo Saravia F, and Ana Caballes
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Topiramate ,Diarrhea ,medicine.medical_specialty ,Fructose ,030226 pharmacology & pharmacy ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,Chronic diarrhea ,Internal medicine ,medicine ,Humans ,Pharmacology (medical) ,Pharmacology ,business.industry ,Metabolic acidosis ,General Medicine ,Middle Aged ,medicine.disease ,Chronic Disease ,Female ,business ,Acidosis ,030217 neurology & neurosurgery ,medicine.drug - Published
- 2017
38. 128 Next-generation RNA sequencing of horse adipose and endometrial mesenchymal stem cells from the same donors unveils striking differences in their transcriptomic pattern
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Navarrete, F., primary, Mellisho, E., additional, Wang, Y., additional, Cabezas, J., additional, Rodriguez-Alvarez, L. L., additional, Navarro, A., additional, Saravia, F., additional, and Castro, F. O., additional
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- 2019
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39. Characterization and quantification of structure and flow in multichannel polymer membranes by MRI
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Schuhmann, S., primary, Simkins, J.W., additional, Schork, N., additional, Codd, S.L., additional, Seymour, J.D., additional, Heijnen, M., additional, Saravia, F., additional, Horn, H., additional, Nirschl, H., additional, and Guthausen, G., additional
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- 2019
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40. Relevamiento de la cupremia en rodeos de cría bovina del chaco semiárido salteño (Argentina)
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Saravia, F. C., primary, Martínez, M. V., additional, and Ávila, G. N., additional
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- 2016
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41. Sperm survival following colloid centrifugation varies according to the part of the sperm-rich fraction used
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Jane Morrell, Saravia F, van Wienen M, Rodriguez-Martinez H, and Wallgren M
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Male ,Sperm Count ,Cell Survival ,Swine ,Sperm Motility ,Animals ,Centrifugation ,Colloids ,Spermatozoa ,Insemination, Artificial - Published
- 2009
42. The Endometrium of Cycling Cows Contains Populations of Putative Mesenchymal Progenitor Cells
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Cabezas, J, primary, Lara, E, additional, Pacha, P, additional, Rojas, D, additional, Veraguas, D, additional, Saravia, F, additional, Rodríguez‐Alvarez, L, additional, and Castro, FO, additional
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- 2014
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43. Preface
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Arzt E, Pérez Leirós C, Rettori, and Saravia F
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Engineering ,Endocrinology ,Neurology ,Endocrine and Autonomic Systems ,business.industry ,Immunology ,Library science ,business - Published
- 2010
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44. Sincronización de estros con GnRH y Prostaglandina F2a en vacas Holstein Friesian en confinamiento
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COX, J. F., CONTRERAS, V., LETELIER, N., SARAVIA, F., SANTA MARIA, A., LOBOS, A., and RECABARREN, S.
- Abstract
The combination of GNRH and prostaglandin F2aallows the control of the luteal phase and the follicular dynamic that coexist in the ovary, facilitating precise oestrus synchronisation schemes. The study was intended to characterise the reproductive response to the use of this combination for an oestrus detection program. The study considered 423 clinically sound dairy cows, from two herds, 1 to 7 calvings and adjusted production levels from 7.500 to 12.500 Kg. Cows were confined under a free-stall system and both herds were under a sanitary and nutritional control program. Since 50 days after calving, cows received 10 µg of buserelin and those having a corpus luteum, based on ultrasound assessment7days later, received 0.75 mg of tiaprost. At the moment of tiaprost administration and 72 h later, milk was collected for progesterone by RIA. The results showed that 90.7% (206/227) cows had a functional corpus luteum at the moment of prostaglandin administration, 93.7% (193/206) responded with luteolysis, and that 85.0%(164/193) showed oestrus behaviour. The interval to the oestrus was 66±15.2 h with 93.9% of cows presenting oestrus between days 2 and 4, with a high percentage (54.9%) presenting oestrus on day 3 after tiaprost administration. Finally, the conception rate was similar to the untreated controls (55.4% (144/269) vs. 50.3% (82/163) for treated vs. untreated respectively. No differences were found between herds in any parameter considered in the study. Based on the results, it can be concluded that the combination of GnRH and PGF2acan be an effective alternative to approach the problem of estrus detection in confined dairy herds., La combinación de análogos GnRH y PGF2apermite controlar la fase luteal y la dinámica folicular que coexisten en el ovario, facilitando el diseño de esquemas de sincronización de estros que mejoren la eficiencia de su detección y subsecuentemente del manejo reproductivo del rebaño. El presente trabajo tuvo como objetivo caracterizar la respuesta reproductiva a esta combinación, utilizando rebaños de alta producción monitoreados ecográficamente y por niveles de progesterona en leche. Se utilizaron 423 vacas lecheras clínicamente sanas, de 1-7 partos y lactancias ajustadas de 7.500 a 12.500 kg, bajo control sanitario y nutricional adecuado. A partir de los 50 días después del parto, las vacas recibieron 10 m g de acetato de buserelina seguido a los 7 días de 0.75 mg de tiaprost cuando presentaban cuerpo lúteo a la evaluación ecográfica. Al momento de la aplicación de tiaprost y 72 h después, se colectaron muestras de leche para evaluar los niveles de progesterona a través de RIA. Se evaluó la eficiencia de las regresiones luteales, el intervalo entre la aplicación de tiaprost y el estro, la eficiencia de detección de estros, in distribución de los estros y la fertilidad subsiguiente al tratamiento. Los resultados mostraron que un 90.7% (206/227) de las vacas tratadas tenían un cuerpo lúteo funcional, un 93,7% (193/206) mespondió con luteólisis a la administración de tiaprost y que un 85% (164/193) fueron detectadas en estro. El intervalo al estro fue de 65.7±16.0 h, distribuyéndose en un 93.9% de los casos entre los días 2 y 4 después del tiaprost, con una fuerte concentración (54.9%) en el día 3. La fertilidad del tratamiento fue similar que la expresada por el rebaño no tratado (5 5,4%, 144/ 260 vs 50.3%, 82/163; p>0.05). No hubo variaciones significativas entre los rebaños en ningún parámetro considerado en el estudio. De acuerdo a los resultados obtenidos, in combinación de análogos GnRH-PGF2apodría ser una alternativa efectiva para enfrentar el problema de detección de estros en rebaños confinados.  
- Published
- 1999
45. Freezing of boar semen can be simplified by handling a specific portion of the ejaculate with a shorter procedure and MiniFlatPack packaging
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Saravia, F., Wallgren, M., Rodriguez-Martinez, Heriberto, Saravia, F., Wallgren, M., and Rodriguez-Martinez, Heriberto
- Abstract
Low sperm survival post-thaw and time-consuming procedures for conventional freezing (CF) hamper the commercial application of cryopreserved boar semen. We had previously proven that boar spermatozoa in the first 10 mL of the sperm-rich fraction, SRF (the so-called PI, the sperm-peak portion of the ejaculate) sustain best handling in vitro, since they probably bathe in an aliquot of seminal plasma (SP) with specific composition. Here, we performed three experiments to determine: Exp I: the concentration of bicarbonate among portions of the ejaculate; Exp II: the effects of bicarbonate doses on sperm motility and; Exp III: the outcome of a faster, simpler freezing method (SF), handling PI-spermatozoa packed in MiniFlatPacks(TM) (MFP) vs. CF and vs. SRF-spermatozoa (2 x 2 factorial design). The bicarbonate content in SP was, among portions/fractions of the ejaculate, lowest in P1 (13.71 mM/L, P less than 0.0001, Exp 1). Boar spermatozoa require bicarbonate in the extender (to the levels present in PI) to maintain acceptable motility over a 120-h period at 16-17 degrees C (Exp II). Sperm freezing was dramatically shortened (from 8 to 3.5 h) by the SF-procedure. P1 - and SRF-spermatozoa survived equally both CF- and SF-freezing (% total motility 30 min PT; P1-CF: 65.2 +/- 5.4% and P1-SF: 68.9 +/- 2.4%; SRF-CF: 64.4 +/- 2.7%; SRF-SF: 55.8 +/- 3.1%, ns). Interestingly. in contrast to SRF, there were no significant variations in 30-min PT-survival among either ejaculates or boars when the P1 was frozen, independent of the handling method (CF or SF). in conclusion, such a faster freezing protocol of semen packed in MFP could be advantageously applied to P1-spermatozoa (P1-SF), while the rest of the ejaculated spermatozoa could still be used for production of conventional artificial insemination (AI) doses, thus allowing for a maintained routine management of commercially relevant stud boars. (C) 2009 Elsevier B.V. All rights reserved.
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- 2010
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46. Spermadhesin PSP-I/PSP-II heterodimer induces migration of polymorphonuclear neutrophils into the uterine cavity of the sow
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Rodriguez-Martinez, Heriberto, Saravia, F., Wallgren, M., A. Martinez, E., Sanz, L., Roca, J., M. Vazquez, J., J. Calvete, J., Rodriguez-Martinez, Heriberto, Saravia, F., Wallgren, M., A. Martinez, E., Sanz, L., Roca, J., M. Vazquez, J., and J. Calvete, J.
- Abstract
Seminal plasma (SP) is a complex fluid which exerts biological actions in the female reproductive tract. In pigs, SP elicits endometrial inflammation and consequent immune changes after mating. This study tested whether heparin-binding spermadhesins (HBPs) and the heterodimer of porcine sperm adhesions I and II (PSP-I/PSP-II) in SP recruit different lymphocyte subsets (CD2(+), CD4(+) and CD8(+) T cells) or polymorphonuclear leukocytes (PMNs) to the superficial endometrium or luminal epithelium and lumen, respectively, of oestrous sows. In Experiment 1, endometrial biopsies were taken between 2 and 120 min after infusion of uterine horns with HBPs, PSP-I/PSP-II or saline and evaluated by immunohistochemistry or histology. In Experiment 2, the uterus of oestrous sows was infused with PSP-I/PSP-II or saline to assess PMN numbers in the uterine lumen 3 h later. PSP-I/PSP-II elicited CD2(+) T cell recruitment from 10 min, and CD8(+) T cells from 60 min after infusion, while HBPs increased CD4(+) T cell recruitment by 120 min. PSP-I/PSP-II but not HBPs induced PMN migration to the surface epithelium by 10 min. PMN numbers were elevated 5-fold by 30 min and 7-fold from 60 min. with PMNs detectable in the lumen from 30 min after infusion. Six-fold more PMNs were collected from the uterine lumen of PSP-I/PSP-II-infused sows compared to controls at 3 h after infusion. These data show that PSP-I/PSP-II heterodimer in seminal plasma has a predominant role in triggering the recruitment of uterine PMNs and T cells after mating, initiating a cascade of transient and long-lasting immunological events. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
- Published
- 2010
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47. Do Cytoplasmic Lipid Droplets Accumulate in Immature Oocytes from Over-Conditioned Repeat Breeder Dairy Heifers?
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Awasthi, H., Saravia, F., Rodriguez-Martinez, Heriberto, Bage, R., Awasthi, H., Saravia, F., Rodriguez-Martinez, Heriberto, and Bage, R.
- Abstract
One of the main sources of repeat breeding in dairy cattle, caused by fertilization failure or early embryonic death, is metabolic stress during lactation. Nutrition seems also to play a role when the condition is seen in heifers, where oocyte cytoplasmic maturation is impaired. To determine whether over conditioning affects oocyte morphology, immature oocytes were collected by ovum pick-up (OPU) twice weekly during 5 weeks from three over-conditioned repeat breeder dairy heifers (RBH) and two normal virgin heifers (VH, controls) of the Swedish Red breed, monitored by body weight and condition. Oocyte quality was assessed under stereomicroscope and further examined by transmission electron microscope for accumulation of cytoplasmic lipid deposits. After OPU, the RBH yielded more low quality oocytes (60% vs 52% for VH, p = 0.14). The relative occupancy of osmophilic lipid droplets in the cytoplasm was higher in oocytes of bad quality compared with good ones, especially in RBH (p = 0.08) but also in VH (p = 0.11). Moreover, the oocytes from over-conditioned RBH showed higher amounts of cytoplasmic lipid deposits both in good (p = 0.14) and, even more prominent, in bad quality oocytes (p = 0.06). Such accumulation of lipid droplets may imply increased sensitivity to oxidative stress, hinder cytoplasmic maturation and lead to subfertility, as accounted in over-conditioned repeat breeders of the Swedish Red breed.
- Published
- 2010
- Full Text
- View/download PDF
48. Spermadhesin PSP-I/PSP-II heterodimer induces migration of polymorphonuclear neutrophils into the uterine cavity of the sow
- Author
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Ministerio de Ciencia e Innovación (España), Rodriguez-Martinez, H., Saravia, F., Wallgren, M., Martinez, E. A., Sanz, Libia, Roca, J., Vazquez, J. M., Calvete, Juan J., Ministerio de Ciencia e Innovación (España), Rodriguez-Martinez, H., Saravia, F., Wallgren, M., Martinez, E. A., Sanz, Libia, Roca, J., Vazquez, J. M., and Calvete, Juan J.
- Abstract
Seminal plasma (SP) is a complex fluid which exerts biological actions in the female reproductive tract. In pigs, SP elicits endometrial inflammation and consequent immune changes after mating. This study tested whether heparin-binding spermadhesins (HBPs) and the heterodimer of porcine sperm adhesions I and II (PSP-I/PSP-II) in SP recruit different lymphocyte subsets (CD2(+), CD4(+) and CD8(+) T cells) or polymorphonuclear leukocytes (PMNs) to the superficial endometrium or luminal epithelium and lumen, respectively, of oestrous sows. In Experiment 1, endometrial biopsies were taken between 2 and 120 min after infusion of uterine horns with HBPs, PSP-I/PSP-II or saline and evaluated by immunohistochemistry or histology. In Experiment 2, the uterus of oestrous sows was infused with PSP-I/PSP-II or saline to assess PMN numbers in the uterine lumen 3h later. PSP-I/PSP-II elicited CD2+ T cell recruitment from 10 min, and CD8(+) T cells from 60 min after infusion, while HBPs increased CD4(+) T cell recruitment by 120 min. PSP-I/PSP-II but not HBPs induced PMN migration to the surface epithelium by 10 min. PMN numbers were elevated 5-fold by 30 min and 7-fold from 60 min, with PMNs detectable in the lumen from 30 min after infusion. Six-fold more PMNs were collected from the uterine lumen of PSP-I/PSP-II-infused sows compared to controls at 3h after infusion. These data show that PSP-I/PSP-II heterodimer in seminal plasma has a predominant role in triggering the recruitment of uterine PMNs and T cells after mating, initiating a cascade of transient and long-lasting immunological events.
- Published
- 2009
49. Use of GnRH and PGF2<FONT FACE=Symbol>a</FONT> for synchronisation of oestrus in confined dairy herds
- Author
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COX, J.F., CONTRERAS, V., LETELIER, N., SARAVIA, F., SANTA MARIA, A., LOBOS, A., and RECABARREN, S.
- Subjects
sincronización de estros ,bovinos ,estrus synchronization ,dairy cattle ,a<%2FFONT>%22">GnRH-PGF2a - Abstract
La combinación de análogos GnRH y PGF2a permite controlar la fase luteal y la dinámica folicular que coexisten en el ovario, facilitando el diseño de esquemas de sincronización de estros que mejoren la eficiencia de su detección y subsecuentemente del manejo reproductivo del rebaño. El presente trabajo tuvo como objetivo caracterizar la respuesta reproductiva a esta combinación, utilizando rebaños de alta producción monitoreados ecográficamente y por niveles de progesterona en leche. Se utilizaron 423 vacas lecheras clínicamente sanas, de 1-7 partos y lactancias ajustadas de 7.500 a 12.500 kg, bajo control sanitario y nutricional adecuado. A partir de los 50 días después del parto, las vacas recibieron 10 m g de acetato de buserelina seguido a los 7 días de 0.75 mg de tiaprost cuando presentaban cuerpo lúteo a la evaluación ecográfica. Al momento de la aplicación de tiaprost y 72 h después, se colectaron muestras de leche para evaluar los niveles de progesterona a través de RIA. Se evaluó la eficiencia de las regresiones luteales, el intervalo entre la aplicación de tiaprost y el estro, la eficiencia de detección de estros, in distribución de los estros y la fertilidad subsiguiente al tratamiento. Los resultados mostraron que un 90.7% (206/227) de las vacas tratadas tenían un cuerpo lúteo funcional, un 93,7% (193/206) mespondió con luteólisis a la administración de tiaprost y que un 85% (164/193) fueron detectadas en estro. El intervalo al estro fue de 65.7±16.0 h, distribuyéndose en un 93.9% de los casos entre los días 2 y 4 después del tiaprost, con una fuerte concentración (54.9%) en el día 3. La fertilidad del tratamiento fue similar que la expresada por el rebaño no tratado (5 5,4%, 144/ 260 vs 50.3%, 82/163; p>0.05). No hubo variaciones significativas entre los rebaños en ningún parámetro considerado en el estudio. De acuerdo a los resultados obtenidos, in combinación de análogos GnRH-PGF2a podría ser una alternativa efectiva para enfrentar el problema de detección de estros en rebaños confinados The combination of GNRH and prostaglandin F2a allows the control of the luteal phase and the follicular dynamic that coexist in the ovary, facilitating precise oestrus synchronisation schemes. The study was intended to characterise the reproductive response to the use of this combination for an oestrus detection program. The study considered 423 clinically sound dairy cows, from two herds, 1 to 7 calvings and adjusted production levels from 7.500 to 12.500 Kg. Cows were confined under a free-stall system and both herds were under a sanitary and nutritional control program. Since 50 days after calving, cows received 10 µg of buserelin and those having a corpus luteum, based on ultrasound assessment 7 days later, received 0.75 mg of tiaprost. At the moment of tiaprost administration and 72 h later, milk was collected for progesterone by RIA. The results showed that 90.7% (206/227) cows had a functional corpus luteum at the moment of prostaglandin administration, 93.7% (193/206) responded with luteolysis, and that 85.0% (164/193) showed oestrus behaviour. The interval to the oestrus was 66±15.2 h with 93.9% of cows presenting oestrus between days 2 and 4, with a high percentage (54.9%) presenting oestrus on day 3 after tiaprost administration. Finally, the conception rate was similar to the untreated controls (55.4% (144/269) vs. 50.3% (82/163) for treated vs. untreated respectively. No differences were found between herds in any parameter considered in the study. Based on the results, it can be concluded that the combination of GnRH and PGF2a can be an effective alternative to approach the problem of estrus detection in confined dairy herds
- Published
- 1999
50. Sincronización de estros con GnRH y Prostaglandina F2a en vacas Holstein Friesian en confinamiento
- Author
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COX,J.F., CONTRERAS,V., LETELIER,N., SARAVIA,F., SANTA MARIA,A., LOBOS,A., and RECABARREN,S.
- Subjects
sincronización de estros ,bovinos ,a<%2FFONT>%22">GnRH-PGF2a - Abstract
La combinación de análogos GnRH y PGF2a permite controlar la fase luteal y la dinámica folicular que coexisten en el ovario, facilitando el diseño de esquemas de sincronización de estros que mejoren la eficiencia de su detección y subsecuentemente del manejo reproductivo del rebaño. El presente trabajo tuvo como objetivo caracterizar la respuesta reproductiva a esta combinación, utilizando rebaños de alta producción monitoreados ecográficamente y por niveles de progesterona en leche. Se utilizaron 423 vacas lecheras clínicamente sanas, de 1-7 partos y lactancias ajustadas de 7.500 a 12.500 kg, bajo control sanitario y nutricional adecuado. A partir de los 50 días después del parto, las vacas recibieron 10 m g de acetato de buserelina seguido a los 7 días de 0.75 mg de tiaprost cuando presentaban cuerpo lúteo a la evaluación ecográfica. Al momento de la aplicación de tiaprost y 72 h después, se colectaron muestras de leche para evaluar los niveles de progesterona a través de RIA. Se evaluó la eficiencia de las regresiones luteales, el intervalo entre la aplicación de tiaprost y el estro, la eficiencia de detección de estros, in distribución de los estros y la fertilidad subsiguiente al tratamiento. Los resultados mostraron que un 90.7% (206/227) de las vacas tratadas tenían un cuerpo lúteo funcional, un 93,7% (193/206) mespondió con luteólisis a la administración de tiaprost y que un 85% (164/193) fueron detectadas en estro. El intervalo al estro fue de 65.7±16.0 h, distribuyéndose en un 93.9% de los casos entre los días 2 y 4 después del tiaprost, con una fuerte concentración (54.9%) en el día 3. La fertilidad del tratamiento fue similar que la expresada por el rebaño no tratado (5 5,4%, 144/ 260 vs 50.3%, 82/163; p>0.05). No hubo variaciones significativas entre los rebaños en ningún parámetro considerado en el estudio. De acuerdo a los resultados obtenidos, in combinación de análogos GnRH-PGF2a podría ser una alternativa efectiva para enfrentar el problema de detección de estros en rebaños confinados
- Published
- 1999
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