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Abstract Background The rapid evolution of nanotechnology has fundamentally transformed both medical and dental fields. By harnessing nanomaterials, researchers have unlocked the ability to replicate natural tissue structures and properties, significantly enhancing integration processes. Notably, nanostructures have emerged as pivotal elements in oral medicine, particularly in combating dental caries and enhancing outcomes in dental implants and maxillofacial surgeries. Main body of the abstract Nanostructures play multifaceted roles in oral health, promoting osseointegration and expediting healing processes in dental procedures. The impact of these materials extends to improving the adhesive strength and overall properties of dental composites. This review critically evaluates the influence of nanointerfaces on the longevity of dental restorations, exploring innovative nanotechnological interventions aimed at augmenting restoration durability. Furthermore, recent strides in nanodentistry are discussed, highlighting breakthroughs in oral health diagnostics, preventative strategies, and treatment modalities essential for achieving and sustaining optimal oral health. Short conclusion Incorporating nanotechnology into dental practice presents exciting prospects for advancing oral healthcare. From enhancing restoration durability to revolutionizing diagnostics and treatments, nanotechnology offers transformative solutions that hold significant promise for the future of oral health management.