733 results on '"Sarafianos, Stefan G."'
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2. Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition
3. Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease
4. Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization
5. The HIV-1 capsid core is an opportunistic nuclear import receptor
6. Activation of HIV-1 proviruses increases downstream chromatin accessibility
7. Structure-based virtual screening workflow to identify antivirals targeting HIV-1 capsid
8. The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
9. Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability
10. Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside
11. HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration.
12. State of the ART (antiretroviral therapy): Long-acting HIV-1 therapeutics.
13. Myrtus communis L. Essential Oil Exhibits Antiviral Activity against Coronaviruses.
14. Novel HIV-1 capsid-targeting small molecules of the PF74 binding site
15. Chemical profiling of HIV-1 capsid-targeting antiviral PF74
16. 7-Deaza-7-fluoro modification confers on 4′-cyano-nucleosides potent activity against entecavir/adefovir-resistant HBV variants and favorable safety
17. Design and Synthesis of New GS-6207 Subtypes for Targeting HIV-1 Capsid Protein
18. Oral Administration of the Nucleoside EFdA (4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine) Provides Rapid Suppression of HIV Viremia in Humanized Mice and Favorable Pharmacokinetic Properties in Mice and the Rhesus Macaque
19. Rotten to the core: antivirals targeting the HIV-1 capsid core
20. Conformational Changes in HIV-1 Reverse Transcriptase that Facilitate Its Maturation
21. Glycosylated diphyllin as a broad-spectrum antiviral agent against Zika virus
22. Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: Tolerance of a nonflexible linker
23. 5-Aminothiophene-2,4-dicarboxamide analogues as hepatitis B virus capsid assembly effectors
24. A Tag‐Free Platform for Synthesis and Screening of Cyclic Peptide Libraries.
25. Proteins and Disease | Structural Basis of HIV Reverse Transcription, Inhibition, and Drug Resistance
26. Use of TSAR, Thermal Shift Analysis in R, to identify Folic Acid as a Molecule that Interacts with HIV-1 Capsid
27. HIV-2 inhibits HIV-1 gene expression via two independent mechanisms during cellular co-infection
28. Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration
29. 6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H
30. 6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity
31. HIV-1 Resistance to Islatravir/Tenofovir Combination Therapy in Wild-Type or NRTI-Resistant Strains of Diverse HIV-1 Subtypes
32. Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H
33. Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase
34. Mutations in the RNase H Domain of HIV-1 Reverse Transcriptase Affect the Initiation of DNA Synthesis and the Specificity of RNase H Cleavage in vivo
35. 6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase
36. Publisher Correction: HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
37. HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
38. Nonnucleoside Reverse Transcriptase Inhibitors are Chemical Enhancers of Dimerization of the HIV Type 1 Reverse Transcriptase
39. Analysis of Mutations at Positions 115 and 116 in the dNTP Binding Site of HIV-1 Reverse Transcriptase
40. Lamivudine (3TC) Resistance in HIV-1 Reverse Transcriptase Involves Steric Hindrance with β -Branched Amino Acids
41. Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA)
42. Strain-specific effect on biphasic DNA binding by HIV-1 integrase
43. Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity
44. Mechanisms of Action of the Host-Targeting Agent Cyclosporin A and Direct-Acting Antiviral Agents against Hepatitis C Virus
45. Targeting the HIV-1 and HBV Capsids, an EnCore
46. TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS
47. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability
48. Nirmatrelvir Resistance in SARS-CoV-2 Omicron_BA.1 and WA1 Replicons and Escape Strategies
49. SARS-CoV-2 Induces Epithelial-Enteric Neuronal Crosstalk Stimulating VIP Release
50. Nirmatrelvir Resistance in SARS-CoV-2 Omicron_BA.1 and WA1 Replicons and Escape Strategies
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