1. Intimate relationship between C–I reductive elimination, aryl scrambling and isomerization processes in Au(<scp>iii</scp>) complexes
- Author
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Sara Fernández-Moyano, Guillermo Marcos-Ayuso, Marconi N. Peñas-Defrutos, Camino Bartolomé, and Pablo Espinet
- Subjects
23 Química ,Materials Chemistry ,Metals and Alloys ,Ceramics and Composites ,Isomerización en complejos ,General Chemistry ,Isomerization processes ,Catalysis ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials - Abstract
Producción Científica, 19F NMR monitoring shows that heating trans-[AuIIIRf2I2]− solutions (Rf = C6F3Cl2-3,5) leads to formation of cis-[AuRf2I2]−, [AuRf3I]− and [AuRfI3]−via kinetic competition between isomerization and Rf/I scrambling. The system evolution is driven by the easy Rf–I reductive elimination from [AuRfI3]− (forming also [AuI2]−), which is faster than any of the Rf–Rf couplings from the coexisting species, hindering the commonly desired and thermodynamically preferred C–C coupling. A kinetic model where I− dissociation triggers both isomerization and transmetalation steps is proposed, which fits well the experimental data. DFT calculations support that the lower bond strength of AuIII–I compared to other halides produces a pathway switch that makes C–I coupling kinetically preferred. Consequently, it is better avoided in reactions looking for C–C coupling.
- Published
- 2023