150 results on '"Santucci, Pierre"'
Search Results
2. Host cell environments and antibiotic efficacy in tuberculosis
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Day, Nathan J., Santucci, Pierre, and Gutierrez, Maximiliano G.
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- 2024
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3. ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages
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Aylan, Beren, Bernard, Elliott M., Pellegrino, Enrica, Botella, Laure, Fearns, Antony, Athanasiadi, Natalia, Bussi, Claudio, Santucci, Pierre, and Gutierrez, Maximiliano G.
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- 2023
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4. Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism
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Bussi, Claudio, Heunis, Tiaan, Pellegrino, Enrica, Bernard, Elliott M., Bah, Nourdine, Dos Santos, Mariana Silva, Santucci, Pierre, Aylan, Beren, Rodgers, Angela, Fearns, Antony, Mitschke, Julia, Moore, Christopher, MacRae, James I., Greco, Maria, Reinheckel, Thomas, Trost, Matthias, and Gutierrez, Maximiliano G.
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- 2022
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5. Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy
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Aitken, Jim, Allen, Zoe, Ambler, Rachel, Ambrose, Karen, Ashton, Emma, Avola, Alida, Balakrishnan, Samutheswari, Barns-Jenkins, Caitlin, Barr, Genevieve, Barrell, Sam, Basu, Souradeep, Beale, Rupert, Beesley, Clare, Bhardwaj, Nisha, Bibi, Shahnaz, Bineva-Todd, Ganka, Biswas, Dhruva, Blackman, Michael J., Bonnet, Dominique, Bowker, Faye, Broncel, Malgorzata, Brooks, Claire, Buck, Michael D., Buckton, Andrew, Budd, Timothy, Burrell, Alana, Busby, Louise, Bussi, Claudio, Butterworth, Simon, Byott, Matthew, Byrne, Fiona, Byrne, Richard, Caidan, Simon, Campbell, Joanna, Canton, Johnathan, Cardoso, Ana, Carter, Nick, Carvalho, Luiz, Carzaniga, Raffaella, Chandler, Natalie, Chen, Qu, Cherepanov, Peter, Churchward, Laura, Clark, Graham, Clayton, Bobbi, Cobolli Gigli, Clementina, Collins, Zena, Cottrell, Sally, Crawford, Margaret, Cubitt, Laura, Cullup, Tom, Davies, Heledd, Davis, Patrick, Davison, Dara, Dearing, Vicky, Debaisieux, Solene, Diaz-Romero, Monica, Dibbs, Alison, Diring, Jessica, Driscoll, Paul C., D'Avola, Annalisa, Earl, Christopher, Edwards, Amelia, Ekin, Chris, Evangelopoulos, Dimitrios, Faraway, Rupert, Fearns, Antony, Ferron, Aaron, Fidanis, Efthymios, Fitz, Dan, Fleming, James, Frampton, Daniel, Frederico, Bruno, Gaiba, Alessandra, Gait, Anthony, Gamblin, Steve, Gärtner, Kathleen, Gaul, Liam, Golding, Helen M., Goldman, Jacki, Goldstone, Robert, Gomez Dominguez, Belen, Gong, Hui, Grant, Paul R., Greco, Maria, Grobler, Mariana, Guedan, Anabel, Gutierrez, Maximiliano G., Hackett, Fiona, Hall, Ross, Halldorsson, Steinar, Harris, Suzanne, Hashim, Sugera, Hatipoglu, Emine, Healy, Lyn, Heaney, Judith, Herbst, Susanne, Hewitt, Graeme, Higgins, Theresa, Hindmarsh, Steve, Hirani, Rajnika, Hope, Joshua, Horton, Elizabeth, Hoskins, Beth, Howell, Michael, Howitt, Louise, Hoyle, Jacqueline, Htun, Mint R., Hubank, Michael, Huerga Encabo, Hector, Hughes, Deborah, Hughes, Jane, Huseynova, Almaz, Hwang, Ming-Shih, Instrell, Rachael, Jackson, Deborah, Jamal-Hanjani, Mariam, Jenkins, Lucy, Jiang, Ming, Johnson, Mark, Jones, Leigh, Kanu, Nnennaya, Kassiotis, George, Kelly, Gavin, Kiely, Louise, Teixeira, Anastacio King Spert, Kirk, Stuart, Kjaer, Svend, Knuepfer, Ellen, Komarov, Nikita, Kotzampaltiris, Paul, Kousis, Konstantinos, Krylova, Tammy, Kucharska, Ania, Labrum, Robyn, Lambe, Catherine, Lappin, Michelle, Lee, Stacey-Ann, Levett, Andrew, Levett, Lisa, Levi, Marcel, Liu, Hon Wing, Loughlin, Sam, Lu, Wei-Ting, MacRae, James I., Madoo, Akshay, Marczak, Julie A., Martensson, Mimmi, Martinez, Thomas, Marzook, Bishara, Matthews, John, Matz, Joachim M., McCall, Samuel, McCoy, Laura E., McKay, Fiona, McNamara, Edel C., Minutti, Carlos M., Mistry, Gita, Molina-Arcas, Miriam, Montaner, Beatriz, Montgomery, Kylie, Moore, Catherine, Moore, David, Moraiti, Anastasia, Moreira-Teixeira, Lucia, Mukherjee, Joyita, Naceur-Lombardelli, Cristina, Nelson, Aileen, Nicod, Jerome, Nightingale, Luke, Nofal, Stephanie, Nurse, Paul, Nutan, Savita, Oedekoven, Caroline, O'Garra, Anne, O'Leary, Jean D., Olsen, Jessica, O'Neill, Olga, O'Reilly, Nicola, Suarez, Paula Ordonez, Osborne, Neil, Pabari, Amar, Pajak, Aleksandra, Papayannopoulos, Venizelos, Paraskevopoulou, Stavroula M, Patel, Namita, Patel, Yogen, Paun, Oana, Peat, Nigel, Peces-Barba Castano, Laura, Caballero, Ana Perez, Perez-Lloret, Jimena, Perrault, Magali S., Perrin, Abigail, Poh, Roy, Poirier, Enzo Z., Polke, James M., Pollitt, Marc, Prieto-Godino, Lucia, Proust, Alize, Puvirajasinghe, Clinda, Queval, Christophe, Ramachandran, Vijaya, Ramaprasad, Abhinay, Ratcliffe, Peter, Reed, Laura, Reis e Sousa, Caetano, Richardson, Kayleigh, Ridewood, Sophie, Roberts, Fiona, Roberts, Rowenna, Rodgers, Angela, Romero Clavijo, Pablo, Rosa, Annachiara, Rossi, Alice, Roustan, Chloe, Rowan, Andrew, Sahai, Erik, Sait, Aaron, Sala, Katarzyna, Sanchez, Emilie, Sanderson, Theo, Santucci, Pierre, Sardar, Fatima, Sateriale, Adam, Saunders, Jill A., Sawyer, Chelsea, Schlott, Anja, Schweighoffer, Edina, Segura-Bayona, Sandra, Shah Punatar, Rajvee, Shahmanesh, Maryam, Shaw, Joe, Silva Dos Santos, Mariana, Silvestre, Margaux, Singer, Matthew, Snell, Daniel M., Song, Ok-Ryul, Spyer, Moira J., Steel, Louisa, Strange, Amy, Sullivan, Adrienne E., Tan, Michele S.Y., Tautz-Davis, Zoe H., Taylor, Effie, Taylor, Gunes, Taylor, Harriet B., Taylor-Beadling, Alison, Teixeira Subtil, Fernanda, Terré Torras, Berta, Toolan-Kerr, Patrick, Torelli, Francesca, Toteva, Tea, Treeck, Moritz, Trojer, Hadija, Tsai, Ming-Han C., Turner, James M.A., Turner, Melanie, Ule, Jernej, Ulferts, Rachel, Vanloo, Sharon P., Veeriah, Selvaraju, Venkatesan, Subramanian, Vousden, Karen, Wack, Andreas, Walder, Claire, Walker, Philip A., Wang, Yiran, Ward, Sophia, Wenman, Catharina, Williams, Luke, Williams, Matthew J., Keong Wong, Wai, Wright, Joshua, Wu, Mary, Wynne, Lauren, Xiang, Zheng, Yap, Melvyn, Zagalak, Julian A., Zecchin, Davide, Zillwood, Rachel, Carthiyaniamma, Santhakumari, DeTisi, Jane, Dick, Julie, Hill, Andrea, Kipper, Karin, Kullar, Birinder, Norris, Sarah, Rugg-Gunn, Fergus, Salvatierra, Rebecca, Shaya, Gabriel, Sloan, Astrid, Singh, Priyanka, Varley, James, Whatley, Ben, Balestrini, Simona, Koepp, Matthias J., Gandhi, Sonia, Rickman, Hannah M., Shin, Gee Yen, Houlihan, Catherine F., Anders-Cannon, Jonny, Silvennoinen, Katri, Xiao, Fenglai, Zagaglia, Sara, Hudgell, Kirsty, Ziomek, Mariusz, Haimes, Paul, Sampson, Adam, Parker, Annie, Helen Cross, J., Pardington, Rosemarie, Nastouli, Eleni, Swanton, Charles, Sander, Josemir W., and Sisodiya, Sanjay M.
- Published
- 2021
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6. Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide
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Santucci, Pierre, Greenwood, Daniel J., Fearns, Antony, Chen, Kai, Jiang, Haibo, and Gutierrez, Maximiliano G.
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- 2021
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7. Intrabacterial lipid inclusion‐associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen Mycobacterium tuberculosis
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Dargham, Tonia, primary, Mallick, Ivy, additional, Kremer, Laurent, additional, Santucci, Pierre, additional, and Canaan, Stéphane, additional
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- 2023
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8. Acinetobacter type VI secretion system comprises a non-canonical membrane complex
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Kandolo, Ona, primary, Cherrak, Yassine, additional, Filella-Merce, Isaac, additional, Le Guenno, Hugo, additional, Kosta, Artemis, additional, Espinosa, Leon, additional, Santucci, Pierre, additional, Verthuy, Christophe, additional, Lebrun, Régine, additional, Nilges, Michael, additional, Pellarin, Riccardo, additional, and Durand, Eric, additional
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- 2023
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9. Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages
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Pellegrino, Enrica, primary, Aylan, Beren, additional, Bussi, Claudio, additional, Fearns, Antony, additional, Bernard, Elliott M., additional, Athanasiadi, Natalia, additional, Santucci, Pierre, additional, Botella, Laure, additional, and Gutierrez, Maximiliano G., additional
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- 2023
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10. Host cell environments and antibiotic efficacy in tuberculosis
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Day, Nathan J., primary, Santucci, Pierre, additional, and Gutierrez, Maximiliano G., additional
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- 2023
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- View/download PDF
11. Meet early career researcher—Ismath Sadhir—Awardee of the molecular microbiology poster prize at the EMBO workshop bacterial morphogenesis, survival and virulence: Dynamic genomes and envelopes
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Santucci, Pierre, primary
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- 2023
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12. Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria
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Santucci, Pierre, Johansen, Matt D., Point, Vanessa, Poncin, Isabelle, Viljoen, Albertus, Cavalier, Jean-François, Kremer, Laurent, and Canaan, Stéphane
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- 2019
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13. Activity and Crystal Structure of the Adherent-Invasive Escherichia coli Tle3/Tli3 T6SS Effector/Immunity Complex Determined Using an AlphaFold2 Predicted Model
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Le, Thi Thu Hang, primary, Kellenberger, Christine, additional, Boyer, Marie, additional, Santucci, Pierre, additional, Flaugnatti, Nicolas, additional, Cascales, Eric, additional, Roussel, Alain, additional, Canaan, Stéphane, additional, Journet, Laure, additional, and Cambillau, Christian, additional
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- 2023
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14. High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages
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Aylan, Beren, primary, Botella, Laure, additional, Gutierrez, Maximiliano G., additional, and Santucci, Pierre, additional
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- 2023
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15. Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism
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Bussi, Claudio, primary, Heunis, Tiaan, additional, Pellegrino, Enrica, additional, Bernard, Elliott M., additional, Bah, Nourdine, additional, dos Santos, Mariana Silva, additional, Santucci, Pierre, additional, Aylan, Beren, additional, Rodgers, Angela, additional, Fearns, Antony, additional, Mitschke, Julia, additional, Moore, Christopher, additional, MacRae, James I., additional, Greco, Maria, additional, Reinheckel, Thomas, additional, Trost, Matthias, additional, and Gutierrez, Maximiliano G., additional
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- 2022
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16. Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis
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Santucci, Pierre, primary, Aylan, Beren, additional, Botella, Laure, additional, Bernard, Elliott M., additional, Bussi, Claudio, additional, Pellegrino, Enrica, additional, Athanasiadi, Natalia, additional, and Gutierrez, Maximiliano G., additional
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- 2022
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17. Indivisions et micro-parcellaires : désordre ou opportunité pour l’agriculture de pente ? , pp.113-145
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Vianey, Gisèle, Paoli, Jean-Christophe, and Santucci, Pierre
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- 2022
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18. Molecular Microbiology of Microbiomes.
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Santucci, Pierre
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MOLECULAR microbiology , *MICROBIAL communities , *CELL envelope (Biology) , *GUT microbiome , *GASTROINTESTINAL diseases , *MICROBIAL ecology - Abstract
The article "Molecular Microbiology of Microbiomes" explores the diverse microbial ecosystems found in various environments, including humans, animals, and plants. Through advanced technologies and interdisciplinary research, scientists aim to understand the composition and function of these microbial communities to address biomedical and environmental challenges. The special issue of Molecular Microbiology highlights key findings on the human gut microbiome, the impact of antibiotics and nonantimicrobial drugs on microbiota, and the potential effects of microbiota-host interactions on brain function and behavior. Additionally, research on microbiomes from a One-Health perspective seeks to improve human health by studying interactions between human bodies, animals, and the environment. [Extracted from the article]
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- 2024
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19. Cell wall architecture and function in microbial physiology
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Santucci, Pierre, primary
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- 2022
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20. Visualizing pyrazinamide action by live single cell imaging of phagosome acidification and Mycobacterium tuberculosis pH homeostasis
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Santucci, Pierre, primary, Aylan, Beren, additional, Botella, Laure, additional, Bernard, Elliott M., additional, Bussi, Claudio, additional, Pellegrino, Enrica, additional, Athanasiadi, Natalia, additional, and Gutierrez, Maximiliano G., additional
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- 2021
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21. Mycobacterium tuberculosis modulates mitochondrial function in human macrophages
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Bussi, Claudio, primary, Silva Dos Santos, Mariana, additional, Bernard, Elliott M., additional, Santucci, Pierre B., additional, Macrae, James I., additional, and Gutierrez, Maximiliano G., additional
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- 2021
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22. Intrabacterial lipid inclusions in mycobacteria: unexpected key players in survival and pathogenesis?
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Mallick, Ivy, primary, Santucci, Pierre, additional, Poncin, Isabelle, additional, Point, Vanessa, additional, Kremer, Laurent, additional, Cavalier, Jean-François, additional, and Canaan, Stéphane, additional
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- 2021
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23. Understanding the Relationships between Extensive Livestock Systems, Land-Cover Changes, and CAP Support in Less-Favored Mediterranean Areas
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Debolini, Marta, Paoli, Jean, Napoleone, Claude, Moulery, Michel, Leonelli, Lara, Santucci, Pierre, Delattre, Laurence, Environnement Méditerranéen et Modélisation des Agro-Hydrosystèmes (EMMAH), Avignon Université (AU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Systèmes d'élevage méditerranéens et tropicaux (UMR SELMET), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité de recherche d'Écodéveloppement (ECODEVELOPPEMENT), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Sciences pour l'environnement (SPE), Centre National de la Recherche Scientifique (CNRS)-Université Pascal Paoli (UPP), Lille économie management - UMR 9221 (LEM), Université d'Artois (UA)-Université catholique de Lille (UCL)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), European Commission, European Commission Joint Research Centre, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Université Pascal Paoli (UPP)-Centre National de la Recherche Scientifique (CNRS), and Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
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lcsh:Agriculture ,land-use change ,extensive livestock systems ,farmer choice drivers ,less favored areas (LFA) ,[SDE]Environmental Sciences ,lcsh:S ,Mediterranean mountainous landscape ,[SHS.ECO]Humanities and Social Sciences/Economics and Finance ,Common Agricultural Policy ,[SHS]Humanities and Social Sciences - Abstract
Farm abandonment and over-extensification trends in less-favored livestock breeding areas in the Mediterranean have led to socio-environmental issues that are difficult to assess and address, due to the characteristics of these areas (e.g., poor data availability and reliability). In a study case that presents many of the characteristics common to these areas, we combine qualitative and quantitative approaches to assess (i) the relationship between livestock production and land-cover change and (ii) the drivers of farmer decisions, concerning the types of livestock they breed. We show that the Common Agricultural Policy&rsquo, s objective of open-landscape preservation cannot be achieved through the observed livestock management practices, with the most heavily CAP subsidy-dependent activities (e.g., suckler-cow breeding) having one of the weakest contributions to this objective. We also econometrically show that suckler-cow breeding is more likely to be adopted as a complementary or main activity in farms facing a labor scarcity and land abundance context. These results complement the literature and contribute to the discussion regarding the design of CAP support for less-favored Mediterranean areas.
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- 2020
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24. M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion
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Bernard, Elliott M., Fearns, Antony, Bussi, Claudio, Santucci, Pierre, Peddie, Christopher J., Lai, Rachel J., Collinson, Lucy M., and Gutierrez, Maximiliano G.
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Stem cell ,Macrophage ,Xenophagy ,Autophagy ,Tuberculosis ,Research Article - Abstract
Xenophagy is an important cellular defence mechanism against cytosol-invading pathogens, such as Mycobacterium tuberculosis (Mtb). Activation of xenophagy in macrophages targets Mtb to autophagosomes; however, how Mtb is targeted to autophagosomes in human macrophages at a high spatial and temporal resolution is unknown. Here, we use human induced pluripotent stem cell-derived macrophages (iPSDMs) to study the human macrophage response to Mtb infection and the role of the ESX-1 type VII secretion system. Using RNA-seq, we identify ESX-1-dependent transcriptional responses in iPSDMs after infection with Mtb. This analysis revealed differential inflammatory responses and dysregulated pathways such as eukaryotic initiation factor 2 (eIF2) signalling and protein ubiquitylation. Moreover, live-cell imaging revealed that Mtb infection in human macrophages induces dynamic ESX-1-dependent, LC3B-positive tubulovesicular autophagosomes (LC3-TVS). Through a correlative live-cell and focused ion beam scanning electron microscopy (FIB SEM) approach, we show that upon phagosomal rupture, Mtb induces the formation of LC3-TVS, from which the bacterium is able to escape to reside in the cytosol. Thus, iPSDMs represent a valuable model for studying spatiotemporal dynamics of human macrophage–Mtb interactions, and Mtb is able to evade capture by autophagic compartments., Summary: Following phagosome membrane damage, Mycobacterium tuberculosis induces the formation of, and escapes from, tubulovesicular autophagosomes in human induced pluripotent stem cell-derived macrophages.
- Published
- 2020
25. Scalable and robust SARS-CoV-2 testing in an academic center
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Aitken, Jim, Ambrose, Karen, Barrell, Sam, Beale, Rupert, Bineva-Todd, Ganka, Biswas, Dhruva, Byrne, Richard, Caidan, Simon, Cherepanov, Peter, Churchward, Laura, Clark, Graham, Crawford, Margaret, Cubitt, Laura, Dearing, Vicky, Earl, Christopher, Edwards, Amelia, Ekin, Chris, Fidanis, Efthymios, Gaiba, Alessandra, Gamblin, Steve, Gandhi, Sonia, Goldman, Jacki, Goldstone, Robert, Grant, Paul R., Greco, Maria, Heaney, Judith, Hindmarsh, Steve, Houlihan, Catherine F., Howell, Michael, Hubank, Michael, Hughes, Deborah, Instrell, Rachael, Jackson, Deborah, Jamal-Hanjani, Mariam, Jiang, Ming, Johnson, Mark, Jones, Leigh, Kanu, Nnennaya, Kassiotis, George, Kirk, Stuart, Kjaer, Svend, Levett, Andrew, Levett, Lisa, Levi, Marcel, Lu, Wei-Ting, MacRae, James I., Matthews, John, McCoy, Laura E., Moore, Catherine, Moore, David, Nastouli, Eleni, Nicod, Jerome, Nightingale, Luke, Olsen, Jessica, O’Reilly, Nicola, Pabari, Amar, Papayannopoulos, Venizelos, Patel, Namita, Peat, Nigel, Pollitt, Marc, Ratcliffe, Peter, Reis e Sousa, Caetano, Rosa, Annachiara, Rosenthal, Rachel, Roustan, Chloe, Rowan, Andrew, Shin, Gee Yen, Snell, Daniel M., Song, Ok-Ryul, Spyer, Moira J., Strange, Amy, Swanton, Charles, Turner, James M. A., Turner, Melanie, Wack, Andreas, Walker, Philip A., Ward, Sophia, Wong, Wai Keong, Wright, Joshua, Wu, Mary, Allen, Zoe, Ambler, Rachel, Ashton, Emma, Avola, Alida, Balakrishnan, Samutheswari, Barns-Jenkins, Caitlin, Barr, Genevieve, Basu, Souradeep, Beesley, Clare, Bhardwaj, Nisha, Bibi, Shahnaz, Blackman, Michael J., Bonnet, Dominique, Bowker, Faye, Broncel, Malgorzata, Brooks, Claire, Buck, Michael D., Buckton, Andrew, Budd, Timothy, Burrell, Alana, Busby, Louise, Bussi, Claudio, Butterworth, Simon, Byrne, Fiona, Campbell, Joanna, Canton, Johnathan, Cardoso, Ana, Carter, Nick, Carvalho, Luiz, Carzaniga, Raffaella, Chandler, Natalie, Chen, Qu, Clayton, Bobbi, Gigli, Clementina Cobolli, Collins, Zena, Cottrell, Sally, Cullup, Tom, Davies, Heledd, Davis, Patrick, Davison, Dara, Debaisieux, Solene, Diaz-Romero, Monica, Dibbs, Alison, Diring, Jessica, Driscoll, Paul C., D’Avola, Annalisa, Evangelopoulos, Dimitrios, Faraway, Rupert, Fearns, Antony, Ferron, Aaron, Dan Fitz, Fleming, James, Frederico, Bruno, Gait, Anthony, Gaul, Liam, Golding, Helen M., Gomez Dominguez, Belen, Gong, Hui, Grobler, Mariana, Guedan, Anabel, Gutierrez, Maximiliano G., Hackett, Fiona, Hall, Ross, Halldorsson, Steinar, Harris, Suzanne, Hashim, Sugera, Healy, Lyn, Herbst, Susanne, Hewitt, Graeme, Higgins, Theresa, Hirani, Rajnika, Hope, Joshua, Horton, Elizabeth, Hoskins, Beth, Howitt, Louise, Hoyle, Jacqueline, Htun, Mint R., Huerga Encabo, Hector, Hughes, Jane, Huseynova, Almaz, Hwang, Ming-Shih, Jenkins, Lucy, Kiely, Louise, King Spert Teixeira, Anastacio, Knuepfer, Ellen, Komarov, Nikita, Kotzampaltiris, Paul, Kousis, Konstantinos, Krylova, Tammy, Kucharska, Ania, Labrum, Robyn, Lambe, Catherine, Lappin, Michelle, Lee, Stacey-Ann, Liu, Hon Wing, Loughlin, Sam, Madoo, Akshay, Marczak, Julie A., Martensson, Mimmi, Martinez, Thomas, Marzook, Bishara, Matz, Joachim M., McCall, Samuel, McKay, Fiona, McNamara, Edel C., Minutti, Carlos M., Mistry, Gita, Molina-Arcas, Miriam, Montaner, Beatriz, Montgomery, Kylie, Moraiti, Anastasia, Moreira-Teixeira, Lucia, Mukherjee, Joyita, Naceur-Lombardelli, Cristina, Nelson, Aileen, Nofal, Stephanie, Nurse, Paul, Nutan, Savita, Oedekoven, Caroline, O’Garra, Anne, O’Leary, Jean D., O’Neill, Olga, Suarez, Paula Ordonez, Osborne, Neil, Pajak, Aleksandra, Patel, Yogen, Paun, Oana, Peces-Barba Castano, Laura, Perez Caballero, Ana, Perez-Lloret, Jimena, Perrault, Magali S., Perrin, Abigail, Poh, Roy, Poirier, Enzo Z., Polke, James M., Prieto-Godino, Lucia, Proust, Alize, Puvirajasinghe, Clinda, Queval, Christophe, Ramachandran, Vijaya, Ramaprasad, Abhinay, Reed, Laura, Richardson, Kayleigh, Ridewood, Sophie, Roberts, Fiona, Roberts, Rowenna, Rodgers, Angela, Clavijo, Pablo Romero, Rossi, Alice, Sahai, Erik, Sait, Aaron, Sala, Katarzyna, Sanderson, Theo, Santucci, Pierre, Sardar, Fatima, Sateriale, Adam, Saunders, Jill A., Sawyer, Chelsea, Schlott, Anja, Schweighoffer, Edina, Segura-Bayona, Sandra, Shah Punatar, Rajvee, Shaw, Joe, Silva Dos Santos, Mariana, Silvestre, Margaux, Singer, Matthew, Steel, Louisa, Sullivan, Adrienne E., Tan, Michele S. Y., Tautz-Davis, Zoe H., Taylor, Effie, Taylor, Gunes, Taylor, Harriet B., Taylor-Beadling, Alison, Teixeira Subtil, Fernanda, Terré Torras, Berta, Toolan-Kerr, Patrick, Torelli, Francesca, Toteva, Tea, Treeck, Moritz, Trojer, Hadija, Tsai, Ming-Han C., Ule, Jernej, Ulferts, Rachel, Vanloo, Sharon P., Veeriah, Selvaraju, Venkatesan, Subramanian, Vousden, Karen, Walder, Claire, Wang, Yiran, Wenman, Catharina, Williams, Luke, Williams, Matthew J., Wynne, Lauren, Xiang, Zheng, Yap, Melvyn, Zagalak, Julian A., Zecchin, Davide, and Zillwood, Rachel
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2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Crick COVID-19 Consortium ,Biomedical Engineering ,Bioengineering ,CORONAVIRUS ,medicine.disease_cause ,Applied Microbiology and Biotechnology ,medicine ,Medical Laboratory Science ,Humans ,Royaume uni ,Coronavirus ,Reino unido ,Science & Technology ,business.industry ,Clinical Laboratory Techniques ,Reverse Transcriptase Polymerase Chain Reaction ,Academies and Institutes ,Virology ,United Kingdom ,Europe ,Biotechnology & Applied Microbiology ,Molecular Medicine ,business ,Coronavirus Infections ,Life Sciences & Biomedicine ,Biotechnology ,PNEUMONIA OUTBREAK - Published
- 2020
26. Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy
- Author
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Balestrini, Simona, primary, Koepp, Matthias J., additional, Gandhi, Sonia, additional, Rickman, Hannah M., additional, Shin, Gee Yen, additional, Houlihan, Catherine F., additional, Anders-Cannon, Jonny, additional, Silvennoinen, Katri, additional, Xiao, Fenglai, additional, Zagaglia, Sara, additional, Hudgell, Kirsty, additional, Ziomek, Mariusz, additional, Haimes, Paul, additional, Sampson, Adam, additional, Parker, Annie, additional, Helen Cross, J., additional, Pardington, Rosemarie, additional, Nastouli, Eleni, additional, Swanton, Charles, additional, Sander, Josemir W., additional, Sisodiya, Sanjay M., additional, Aitken, Jim, additional, Allen, Zoe, additional, Ambler, Rachel, additional, Ambrose, Karen, additional, Ashton, Emma, additional, Avola, Alida, additional, Balakrishnan, Samutheswari, additional, Barns-Jenkins, Caitlin, additional, Barr, Genevieve, additional, Barrell, Sam, additional, Basu, Souradeep, additional, Beale, Rupert, additional, Beesley, Clare, additional, Bhardwaj, Nisha, additional, Bibi, Shahnaz, additional, Bineva-Todd, Ganka, additional, Biswas, Dhruva, additional, Blackman, Michael J., additional, Bonnet, Dominique, additional, Bowker, Faye, additional, Broncel, Malgorzata, additional, Brooks, Claire, additional, Buck, Michael D., additional, Buckton, Andrew, additional, Budd, Timothy, additional, Burrell, Alana, additional, Busby, Louise, additional, Bussi, Claudio, additional, Butterworth, Simon, additional, Byott, Matthew, additional, Byrne, Fiona, additional, Byrne, Richard, additional, Caidan, Simon, additional, Campbell, Joanna, additional, Canton, Johnathan, additional, Cardoso, Ana, additional, Carter, Nick, additional, Carvalho, Luiz, additional, Carzaniga, Raffaella, additional, Chandler, Natalie, additional, Chen, Qu, additional, Cherepanov, Peter, additional, Churchward, Laura, additional, Clark, Graham, additional, Clayton, Bobbi, additional, Cobolli Gigli, Clementina, additional, Collins, Zena, additional, Cottrell, Sally, additional, Crawford, Margaret, additional, Cubitt, Laura, additional, Cullup, Tom, additional, Davies, Heledd, additional, Davis, Patrick, additional, Davison, Dara, additional, Dearing, Vicky, additional, Debaisieux, Solene, additional, Diaz-Romero, Monica, additional, Dibbs, Alison, additional, Diring, Jessica, additional, Driscoll, Paul C., additional, D'Avola, Annalisa, additional, Earl, Christopher, additional, Edwards, Amelia, additional, Ekin, Chris, additional, Evangelopoulos, Dimitrios, additional, Faraway, Rupert, additional, Fearns, Antony, additional, Ferron, Aaron, additional, Fidanis, Efthymios, additional, Fitz, Dan, additional, Fleming, James, additional, Frampton, Daniel, additional, Frederico, Bruno, additional, Gaiba, Alessandra, additional, Gait, Anthony, additional, Gamblin, Steve, additional, Gärtner, Kathleen, additional, Gaul, Liam, additional, Golding, Helen M., additional, Goldman, Jacki, additional, Goldstone, Robert, additional, Gomez Dominguez, Belen, additional, Gong, Hui, additional, Grant, Paul R., additional, Greco, Maria, additional, Grobler, Mariana, additional, Guedan, Anabel, additional, Gutierrez, Maximiliano G., additional, Hackett, Fiona, additional, Hall, Ross, additional, Halldorsson, Steinar, additional, Harris, Suzanne, additional, Hashim, Sugera, additional, Hatipoglu, Emine, additional, Healy, Lyn, additional, Heaney, Judith, additional, Herbst, Susanne, additional, Hewitt, Graeme, additional, Higgins, Theresa, additional, Hindmarsh, Steve, additional, Hirani, Rajnika, additional, Hope, Joshua, additional, Horton, Elizabeth, additional, Hoskins, Beth, additional, Howell, Michael, additional, Howitt, Louise, additional, Hoyle, Jacqueline, additional, Htun, Mint R., additional, Hubank, Michael, additional, Huerga Encabo, Hector, additional, Hughes, Deborah, additional, Hughes, Jane, additional, Huseynova, Almaz, additional, Hwang, Ming-Shih, additional, Instrell, Rachael, additional, Jackson, Deborah, additional, Jamal-Hanjani, Mariam, additional, Jenkins, Lucy, additional, Jiang, Ming, additional, Johnson, Mark, additional, Jones, Leigh, additional, Kanu, Nnennaya, additional, Kassiotis, George, additional, Kelly, Gavin, additional, Kiely, Louise, additional, Teixeira, Anastacio King Spert, additional, Kirk, Stuart, additional, Kjaer, Svend, additional, Knuepfer, Ellen, additional, Komarov, Nikita, additional, Kotzampaltiris, Paul, additional, Kousis, Konstantinos, additional, Krylova, Tammy, additional, Kucharska, Ania, additional, Labrum, Robyn, additional, Lambe, Catherine, additional, Lappin, Michelle, additional, Lee, Stacey-Ann, additional, Levett, Andrew, additional, Levett, Lisa, additional, Levi, Marcel, additional, Liu, Hon Wing, additional, Loughlin, Sam, additional, Lu, Wei-Ting, additional, MacRae, James I., additional, Madoo, Akshay, additional, Marczak, Julie A., additional, Martensson, Mimmi, additional, Martinez, Thomas, additional, Marzook, Bishara, additional, Matthews, John, additional, Matz, Joachim M., additional, McCall, Samuel, additional, McCoy, Laura E., additional, McKay, Fiona, additional, McNamara, Edel C., additional, Minutti, Carlos M., additional, Mistry, Gita, additional, Molina-Arcas, Miriam, additional, Montaner, Beatriz, additional, Montgomery, Kylie, additional, Moore, Catherine, additional, Moore, David, additional, Moraiti, Anastasia, additional, Moreira-Teixeira, Lucia, additional, Mukherjee, Joyita, additional, Naceur-Lombardelli, Cristina, additional, Nelson, Aileen, additional, Nicod, Jerome, additional, Nightingale, Luke, additional, Nofal, Stephanie, additional, Nurse, Paul, additional, Nutan, Savita, additional, Oedekoven, Caroline, additional, O'Garra, Anne, additional, O'Leary, Jean D., additional, Olsen, Jessica, additional, O'Neill, Olga, additional, O'Reilly, Nicola, additional, Suarez, Paula Ordonez, additional, Osborne, Neil, additional, Pabari, Amar, additional, Pajak, Aleksandra, additional, Papayannopoulos, Venizelos, additional, Paraskevopoulou, Stavroula M, additional, Patel, Namita, additional, Patel, Yogen, additional, Paun, Oana, additional, Peat, Nigel, additional, Peces-Barba Castano, Laura, additional, Caballero, Ana Perez, additional, Perez-Lloret, Jimena, additional, Perrault, Magali S., additional, Perrin, Abigail, additional, Poh, Roy, additional, Poirier, Enzo Z., additional, Polke, James M., additional, Pollitt, Marc, additional, Prieto-Godino, Lucia, additional, Proust, Alize, additional, Puvirajasinghe, Clinda, additional, Queval, Christophe, additional, Ramachandran, Vijaya, additional, Ramaprasad, Abhinay, additional, Ratcliffe, Peter, additional, Reed, Laura, additional, Reis e Sousa, Caetano, additional, Richardson, Kayleigh, additional, Ridewood, Sophie, additional, Roberts, Fiona, additional, Roberts, Rowenna, additional, Rodgers, Angela, additional, Romero Clavijo, Pablo, additional, Rosa, Annachiara, additional, Rossi, Alice, additional, Roustan, Chloe, additional, Rowan, Andrew, additional, Sahai, Erik, additional, Sait, Aaron, additional, Sala, Katarzyna, additional, Sanchez, Emilie, additional, Sanderson, Theo, additional, Santucci, Pierre, additional, Sardar, Fatima, additional, Sateriale, Adam, additional, Saunders, Jill A., additional, Sawyer, Chelsea, additional, Schlott, Anja, additional, Schweighoffer, Edina, additional, Segura-Bayona, Sandra, additional, Shah Punatar, Rajvee, additional, Shahmanesh, Maryam, additional, Shaw, Joe, additional, Silva Dos Santos, Mariana, additional, Silvestre, Margaux, additional, Singer, Matthew, additional, Snell, Daniel M., additional, Song, Ok-Ryul, additional, Spyer, Moira J., additional, Steel, Louisa, additional, Strange, Amy, additional, Sullivan, Adrienne E., additional, Tan, Michele S.Y., additional, Tautz-Davis, Zoe H., additional, Taylor, Effie, additional, Taylor, Gunes, additional, Taylor, Harriet B., additional, Taylor-Beadling, Alison, additional, Teixeira Subtil, Fernanda, additional, Terré Torras, Berta, additional, Toolan-Kerr, Patrick, additional, Torelli, Francesca, additional, Toteva, Tea, additional, Treeck, Moritz, additional, Trojer, Hadija, additional, Tsai, Ming-Han C., additional, Turner, James M.A., additional, Turner, Melanie, additional, Ule, Jernej, additional, Ulferts, Rachel, additional, Vanloo, Sharon P., additional, Veeriah, Selvaraju, additional, Venkatesan, Subramanian, additional, Vousden, Karen, additional, Wack, Andreas, additional, Walder, Claire, additional, Walker, Philip A., additional, Wang, Yiran, additional, Ward, Sophia, additional, Wenman, Catharina, additional, Williams, Luke, additional, Williams, Matthew J., additional, Keong Wong, Wai, additional, Wright, Joshua, additional, Wu, Mary, additional, Wynne, Lauren, additional, Xiang, Zheng, additional, Yap, Melvyn, additional, Zagalak, Julian A., additional, Zecchin, Davide, additional, Zillwood, Rachel, additional, Carthiyaniamma, Santhakumari, additional, DeTisi, Jane, additional, Dick, Julie, additional, Hill, Andrea, additional, Kipper, Karin, additional, Kullar, Birinder, additional, Norris, Sarah, additional, Rugg-Gunn, Fergus, additional, Salvatierra, Rebecca, additional, Shaya, Gabriel, additional, Sloan, Astrid, additional, Singh, Priyanka, additional, Varley, James, additional, and Whatley, Ben, additional
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- 2021
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27. Understanding the Relationships between Extensive Livestock Systems, Land-Cover Changes, and CAP Support in Less-Favored Mediterranean Areas
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Delattre, Laurence, primary, Debolini, Marta, additional, Paoli, Jean Christophe, additional, Napoleone, Claude, additional, Moulery, Michel, additional, Leonelli, Lara, additional, and Santucci, Pierre, additional
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- 2020
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28. Intracellular pathogens, membrane damage and cytosolic access
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Santucci, Pierre, primary
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- 2020
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29. Intracellular localisation ofMycobacterium tuberculosisaffects antibiotic efficacy
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Santucci, Pierre, primary, Greenwood, Daniel J., additional, Fearns, Antony, additional, Chen, Kai, additional, Jiang, Haibo, additional, and Gutierrez, Maximiliano G., additional
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- 2020
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30. Mycobacterium tuberculosis modulates mitochondrial function in human macrophages
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Bussi, Claudio, primary, Silva Dos Santos, Mariana, additional, Bernard, Elliott M., additional, Santucci, Pierre, additional, Macrae, James I., additional, and Gutierrez, Maximiliano G., additional
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- 2020
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31. Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers
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Houlihan, Catherine F, primary, Vora, Nina, additional, Byrne, Thomas, additional, Lewer, Dan, additional, Kelly, Gavin, additional, Heaney, Judith, additional, Gandhi, Sonia, additional, Spyer, Moira J, additional, Beale, Rupert, additional, Cherepanov, Peter, additional, Moore, David, additional, Gilson, Richard, additional, Gamblin, Steve, additional, Kassiotis, George, additional, McCoy, Laura E, additional, Swanton, Charles, additional, Hayward, Andrew, additional, Nastouli, Eleni, additional, Aitken, Jim, additional, Allen, Zoe, additional, Ambler, Rachel, additional, Ambrose, Karen, additional, Ashton, Emma, additional, Avola, Alida, additional, Balakrishnan, Samutheswari, additional, Barns-Jenkins, Caitlin, additional, Barr, Genevieve, additional, Barrell, Sam, additional, Basu, Souradeep, additional, Beesley, Clare, additional, Bhardwaj, Nisha, additional, Bibi, Shahnaz, additional, Bineva-Todd, Ganka, additional, Biswas, Dhruva, additional, Blackman, Michael J, additional, Bonnet, Dominique, additional, Bowker, Faye, additional, Broncel, Malgorzata, additional, Brooks, Claire, additional, Buck, Michael D, additional, Buckton, Andrew, additional, Budd, Timothy, additional, Burrell, Alana, additional, Busby, Louise, additional, Bussi, Claudio, additional, Butterworth, Simon, additional, Byrne, Fiona, additional, Byrne, Richard, additional, Caidan, Simon, additional, Campbell, Joanna, additional, Canton, Johnathan, additional, Cardoso, Ana, additional, Carter, Nick, additional, Carvalho, Luiz, additional, Carzaniga, Raffaella, additional, Chandler, Natalie, additional, Chen, Qu, additional, Churchward, Laura, additional, Clark, Graham, additional, Clayton, Bobbi, additional, Cobolli Gigli, Clementina, additional, Collins, Zena, additional, Cottrell, Sally, additional, Crawford, Margaret, additional, Cubitt, Laura, additional, Cullup, Tom, additional, Davies, Heledd, additional, Davis, Patrick, additional, Davison, Dara, additional, D'Avola, Annalisa, additional, Dearing, Vicky, additional, Debaisieux, Solene, additional, Diaz-Romero, Monica, additional, Dibbs, Alison, additional, Diring, Jessica, additional, Driscoll, Paul C, additional, Earl, Christopher, additional, Edwards, Amelia, additional, Ekin, Chris, additional, Evangelopoulos, Dimitrios, additional, Faraway, Rupert, additional, Fearns, Antony, additional, Ferron, Aaron, additional, Fidanis, Efthymios, additional, Fitz, Dan, additional, Fleming, James, additional, Frederico, Bruno, additional, Gaiba, Alessandra, additional, Gait, Anthony, additional, Gaul, Liam, additional, Golding, Helen M, additional, Goldman, Jacki, additional, Goldstone, Robert, additional, Gomez Dominguez, Belen, additional, Gong, Hui, additional, Grant, Paul R, additional, Greco, Maria, additional, Grobler, Mariana, additional, Guedan, Anabel, additional, Gutierrez, Maximiliano G, additional, Hackett, Fiona, additional, Hall, Ross, additional, Halldorsson, Steinar, additional, Harris, Suzanne, additional, Hashim, Sugera, additional, Healy, Lyn, additional, Herbst, Susanne, additional, Hewitt, Graeme, additional, Higgins, Theresa, additional, Hindmarsh, Steve, additional, Hirani, Rajnika, additional, Hope, Joshua, additional, Horton, Elizabeth, additional, Hoskins, Beth, additional, Houlihan, Catherine F, additional, Howell, Michael, additional, Howitt, Louise, additional, Hoyle, Jacqueline, additional, Htun, Mint R, additional, Hubank, Michael, additional, Huerga Encabo, Hector, additional, Hughes, Deborah, additional, Hughes, Jane, additional, Huseynova, Almaz, additional, Hwang, Ming-Shih, additional, Instrell, Rachael, additional, Jackson, Deborah, additional, Jamal-Hanjani, Mariam, additional, Jenkins, Lucy, additional, Jiang, Ming, additional, Johnson, Mark, additional, Jones, Leigh, additional, Kanu, Nnennaya, additional, Kiely, Louise, additional, King Spert Teixeira, Anastacio, additional, Kirk, Stuart, additional, Kjaer, Svend, additional, Knuepfer, Ellen, additional, Komarov, Nikita, additional, Kotzampaltiris, Paul, additional, Kousis, Konstantinos, additional, Krylova, Tammy, additional, Kucharska, Ania, additional, Labrum, Robyn, additional, Lambe, Catherine, additional, Lappin, Michelle, additional, Lee, Stacey-Ann, additional, Levett, Andrew, additional, Levett, Lisa, additional, Levi, Marcel, additional, Liu, Hon-Wing, additional, Loughlin, Sam, additional, Lu, Wei-Ting, additional, MacRae, James I, additional, Madoo, Akshay, additional, Marczak, Julie A, additional, Martensson, Mimmi, additional, Martinez, Thomas, additional, Marzook, Bishara, additional, Matthews, John, additional, Matz, Joachim M, additional, McCall, Samuel, additional, McKay, Fiona, additional, McNamara, Edel C, additional, Minutti, Carlos M, additional, Mistry, Gita, additional, Molina-Arcas, Miriam, additional, Montaner, Beatriz, additional, Montgomery, Kylie, additional, Moore, Catherine, additional, Moraiti, Anastasia, additional, Moreira-Teixeira, Lucia, additional, Mukherjee, Joyita, additional, Naceur-Lombardelli, Cristina, additional, Nelson, Aileen, additional, Nicod, Jerome, additional, Nightingale, Luke, additional, Nofal, Stephanie, additional, Nurse, Paul, additional, Nutan, Savita, additional, Oedekoven, Caroline, additional, O'Garra, Anne, additional, O'Leary, Jean D, additional, Olsen, Jessica, additional, O'Neill, Olga, additional, Ordonez Suarez, Paula, additional, O'Reilly, Nicola, additional, Osborne, Neil, additional, Pabari, Amar, additional, Pajak, Aleksandra, additional, Papayannopoulos, Venizelos, additional, Patel, Namita, additional, Patel, Yogen, additional, Paun, Oana, additional, Peat, Nigel, additional, Peces-Barba Castano, Laura, additional, Perez Caballero, Ana, additional, Perez-Lloret, Jimena, additional, Perrault, Magali S, additional, Perrin, Abigail, additional, Poh, Roy, additional, Poirier, Enzo Z, additional, Polke, James M, additional, Pollitt, Marc, additional, Prieto-Godino, Lucia, additional, Proust, Alize, additional, Shah Punatar, Rajvee, additional, Puvirajasinghe, Clinda, additional, Queval, Christophe, additional, Ramachandran, Vijaya, additional, Ramaprasad, Abhinay, additional, Ratcliffe, Peter, additional, Reed, Laura, additional, Reis e Sousa, Caetano, additional, Richardson, Kayleigh, additional, Ridewood, Sophie, additional, Roberts, Rowenna, additional, Rodgers, Angela, additional, Romero Clavijo, Pablo, additional, Rosa, Annachiara, additional, Rossi, Alice, additional, Roustan, Chloe, additional, Rowan, Andrew, additional, Sahai, Erik, additional, Sait, Aaron, additional, Sala, Katarzyna, additional, Sanderson, Theo, additional, Santucci, Pierre, additional, Sardar, Fatima, additional, Sateriale, Adam, additional, Saunders, Jill A, additional, Sawyer, Chelsea, additional, Schlott, Anja, additional, Schweighoffer, Edina, additional, Segura-Bayona, Sandra, additional, Shaw, Joe, additional, Shin, Gee Yen, additional, Silva Dos Santos, Mariana, additional, Silvestre, Margaux, additional, Singer, Matthew, additional, Snell, Daniel M, additional, Song, Ok-Ryul, additional, Steel, Louisa, additional, Strange, Amy, additional, Sullivan, Adrienne E, additional, Tan, Michele SY, additional, Tautz-Davis, Zoe H, additional, Taylor, Effie, additional, Taylor, Gunes, additional, Taylor, Harriet B, additional, Taylor-Beadling, Alison, additional, Teixeira Subtil, Fernanda, additional, Terré Torras, Berta, additional, Toolan-Kerr, Patrick, additional, Torelli, Francesca, additional, Toteva, Tea, additional, Treeck, Moritz, additional, Trojer, Hadija, additional, Tsai, Ming-Han C, additional, Turner, James MA, additional, Turner, Melanie, additional, Ule, Jernej, additional, Ulferts, Rachel, additional, Vanloo, Sharon P, additional, Veeriah, Selvaraju, additional, Venkatesan, Subramanian, additional, Vousden, Karen, additional, Wack, Andreas, additional, Walder, Claire, additional, Walker, Philip A, additional, Wang, Yiran, additional, Ward, Sophia, additional, Wenman, Catharina, additional, Wiliams, Luke, additional, Williams, Matthew J, additional, Wong, Wai Keong, additional, Wright, Joshua, additional, Wu, Mary, additional, Wynne, Lauren, additional, Xiang, Zheng, additional, Yap, Melvyn, additional, Zagalak, Julian A, additional, Zecchin, Davide, additional, Zillwood, Rachel, additional, Matthews, Rebecca, additional, Severn, Abigail, additional, Adam, Sajida, additional, Enfield, Louise, additional, McBride, Angela, additional, Gärtner, Kathleen, additional, Edwards, Sarah, additional, Lorencatto, Fabiana, additional, Michie, Susan, additional, Manley, Ed, additional, Shahmanesh, Maryam, additional, Lukha, Hinal, additional, Prymas, Paulina, additional, McBain, Hazel, additional, Shortman, Robert, additional, Wood, Leigh, additional, Davies, Claudia, additional, Williams, Bethany, additional, Ng, Kevin W, additional, Cornish, Georgina H, additional, Faulkner, Nikhil, additional, Riddell, Andrew, additional, Hobson, Philip, additional, Agua-Doce, Ana, additional, Bartolovic, Kerol, additional, Russell, Emma, additional, Carr, Lotte, additional, Sanchez, Emilie, additional, Frampton, Daniel, additional, Byott, Matthew, additional, Paraskevopoulou, Stavroula M, additional, Crayton, Elise, additional, Meyer, Carly, additional, Gkouleli, Triantafylia, additional, Stoltenberg, Andrea, additional, Ranieri, Veronica, additional, Byrne, Tom, additional, Roberts, Fiona, additional, and Hatipoglu, Emine, additional
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- 2020
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32. M. tuberculosis infection of human iPSDM reveals complex membrane dynamics during xenophagy evasion
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Bernard, Elliott M., primary, Fearns, Antony, additional, Bussi, Claudio, additional, Santucci, Pierre, additional, Peddie, Christopher J., additional, Lai, Rachel J., additional, Collinson, Lucy M., additional, and Gutierrez, Maximiliano G., additional
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- 2020
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33. LipG a bifunctional phospholipase/thioesterase involved in mycobacterial envelope remodeling
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Santucci, Pierre, Point, Vanessa, Poncin, Isabelle, Guy, Alexandre, Crauste, Céline, Serveau-Avesque, Carole, Galano, Jean Marie, Spilling, Chistopher D., Cavalier, Jean-François, Canaan, Stéphane, Laboratoire d'ingénierie des systèmes macromoléculaires (LISM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut des Sciences Moléculaires (ISM), Université Montesquieu - Bordeaux 4-Université Sciences et Technologies - Bordeaux 1-École Nationale Supérieure de Chimie et de Physique de Bordeaux (ENSCPB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), University of Missouri [St. Louis], University of Missouri System, Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and Université Montesquieu - Bordeaux 4-Université Sciences et Technologies - Bordeaux 1 (UB)-École Nationale Supérieure de Chimie et de Physique de Bordeaux (ENSCPB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
[SDV]Life Sciences [q-bio] ,Mycobacterium smegmatis ,Phosphatidylinositols ,phospholipid homeostasis ,antibiotics ,cell- 16 ,Mice ,cell-envelope ,Cell Wall ,Animals ,Humans ,Tuberculosis ,[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology ,Research Articles ,lipolytic enzymes ,Macrophages ,Glycopeptides ,Mycobacterium tuberculosis ,Anti-Bacterial Agents ,[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology ,Phospholipases ,Glycolipids ,Research Article - Abstract
International audience; Tuberculosis caused by Mycobacterium tuberculosis is currently one of the leading causes of death from an infectious agent. The main difficulties encountered in eradicating this bacteria are mainly related to (i) a very complex lipid composition of the bacillus cell wall, (ii) its ability to hide from the immune system inside the granulomas, and (iii) the increasing number of resistant strains. In this context, we were interested in the Rv0646c (lipGMTB) gene located upstream to the mmaA cluster which is described as being crucial for the production of cell wall components and required for the bacilli adaptation and survival in mouse macrophages. Using biochemical experiments combined with the construction of deletion and overexpression mutant strains in Mycobacterium smegmatis, we found that LipGMTB is a cytoplasmic membrane-associated enzyme that displays both phospholipase and thioesterase activities. Overproduction of LipGMTB decreases the glycopeptidolipids (GPL) level concomitantly to an increase in phosphatidylinositol (PI) which is the precursor of the PI mannoside (PIM), an essential lipid component of the bacterial cell wall. Conversely, deletion of the lipGMS gene in M. smegmatis leads to an overproduction of GPL, and subsequently decreases the strain susceptibility to various antibiotics. All these findings demonstrate that LipG is involved in cell envelope biosynthesis/remodeling, and consequently this enzyme may thus play an important role in mycobacterial physiology.
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- 2018
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34. Dissecting the membrane lipid binding properties and lipase activity of Mycobacterium tuberculosis LipY domains
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Santucci, Pierre, primary, Smichi, Nabil, additional, Diomandé, Sadia, additional, Poncin, Isabelle, additional, Point, Vanessa, additional, Gaussier, Hélène, additional, Cavalier, Jean‐François, additional, Kremer, Laurent, additional, and Canaan, Stéphane, additional
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- 2019
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35. Synthesis of Long‐Chain β‐Lactones and Their Antibacterial Activities against Pathogenic Mycobacteria
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Santucci, Pierre, primary, Dedaki, Christina, additional, Athanasoulis, Alexandros, additional, Gallorini, Laura, additional, Munoz, Anaïs, additional, Canaan, Stéphane, additional, Cavalier, Jean‐François, additional, and Magrioti, Victoria, additional
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- 2019
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36. Lipid Droplets Breakdown: Adipose Triglyceride Lipase Leads the Way
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Santucci, Pierre, primary and Canaan, Stephane, additional
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- 2018
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37. Delineating the Physiological Roles of the PE and Catalytic Domains of LipY in Lipid Consumption in Mycobacterium-Infected Foamy Macrophages
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Santucci, Pierre, primary, Diomandé, Sadia, additional, Poncin, Isabelle, additional, Alibaud, Laetitia, additional, Viljoen, Albertus, additional, Kremer, Laurent, additional, de Chastellier, Chantal, additional, and Canaan, Stéphane, additional
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- 2018
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38. Cyclophostin and Cyclipostins analogues, new promising molecules to treat mycobacterial-related diseases
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Nguyen, Phuong Chi, primary, Madani, Abdeldjalil, additional, Santucci, Pierre, additional, Martin, Benjamin P., additional, Paudel, Rishi R., additional, Delattre, Sandrine, additional, Herrmann, Jean-Louis, additional, Spilling, Christopher D., additional, Kremer, Laurent, additional, Canaan, Stéphane, additional, and Cavalier, Jean-François, additional
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- 2018
- Full Text
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39. Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers
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Aitken, Jim, Allen, Zoe, Ambler, Rachel, Ambrose, Karen, Ashton, Emma, Avola, Alida, Balakrishnan, Samutheswari, Barns-Jenkins, Caitlin, Barr, Genevieve, Barrell, Sam, Basu, Souradeep, Beale, Rupert, Beesley, Clare, Bhardwaj, Nisha, Bibi, Shahnaz, Bineva-Todd, Ganka, Biswas, Dhruva, Blackman, Michael J, Bonnet, Dominique, Bowker, Faye, Broncel, Malgorzata, Brooks, Claire, Buck, Michael D, Buckton, Andrew, Budd, Timothy, Burrell, Alana, Busby, Louise, Bussi, Claudio, Butterworth, Simon, Byrne, Fiona, Byrne, Richard, Caidan, Simon, Campbell, Joanna, Canton, Johnathan, Cardoso, Ana, Carter, Nick, Carvalho, Luiz, Carzaniga, Raffaella, Chandler, Natalie, Chen, Qu, Cherepanov, Peter, Churchward, Laura, Clark, Graham, Clayton, Bobbi, Cobolli Gigli, Clementina, Collins, Zena, Cottrell, Sally, Crawford, Margaret, Cubitt, Laura, Cullup, Tom, Davies, Heledd, Davis, Patrick, Davison, Dara, D'Avola, Annalisa, Dearing, Vicky, Debaisieux, Solene, Diaz-Romero, Monica, Dibbs, Alison, Diring, Jessica, Driscoll, Paul C, Earl, Christopher, Edwards, Amelia, Ekin, Chris, Evangelopoulos, Dimitrios, Faraway, Rupert, Fearns, Antony, Ferron, Aaron, Fidanis, Efthymios, Fitz, Dan, Fleming, James, Frederico, Bruno, Gaiba, Alessandra, Gait, Anthony, Gamblin, Steve, Gandhi, Sonia, Gaul, Liam, Golding, Helen M, Goldman, Jacki, Goldstone, Robert, Gomez Dominguez, Belen, Gong, Hui, Grant, Paul R, Greco, Maria, Grobler, Mariana, Guedan, Anabel, Gutierrez, Maximiliano G, Hackett, Fiona, Hall, Ross, Halldorsson, Steinar, Harris, Suzanne, Hashim, Sugera, Healy, Lyn, Heaney, Judith, Herbst, Susanne, Hewitt, Graeme, Higgins, Theresa, Hindmarsh, Steve, Hirani, Rajnika, Hope, Joshua, Horton, Elizabeth, Hoskins, Beth, Houlihan, Catherine F, Howell, Michael, Howitt, Louise, Hoyle, Jacqueline, Htun, Mint R, Hubank, Michael, Huerga Encabo, Hector, Hughes, Deborah, Hughes, Jane, Huseynova, Almaz, Hwang, Ming-Shih, Instrell, Rachael, Jackson, Deborah, Jamal-Hanjani, Mariam, Jenkins, Lucy, Jiang, Ming, Johnson, Mark, Jones, Leigh, Kanu, Nnennaya, Kassiotis, George, Kiely, Louise, King Spert Teixeira, Anastacio, Kirk, Stuart, Kjaer, Svend, Knuepfer, Ellen, Komarov, Nikita, Kotzampaltiris, Paul, Kousis, Konstantinos, Krylova, Tammy, Kucharska, Ania, Labrum, Robyn, Lambe, Catherine, Lappin, Michelle, Lee, Stacey-Ann, Levett, Andrew, Levett, Lisa, Levi, Marcel, Liu, Hon-Wing, Loughlin, Sam, Lu, Wei-Ting, MacRae, James I, Madoo, Akshay, Marczak, Julie A, Martensson, Mimmi, Martinez, Thomas, Marzook, Bishara, Matthews, John, Matz, Joachim M, McCall, Samuel, McCoy, Laura E, McKay, Fiona, McNamara, Edel C, Minutti, Carlos M, Mistry, Gita, Molina-Arcas, Miriam, Montaner, Beatriz, Montgomery, Kylie, Moore, Catherine, Moore, David, Moraiti, Anastasia, Moreira-Teixeira, Lucia, Mukherjee, Joyita, Naceur-Lombardelli, Cristina, Nastouli, Eleni, Nelson, Aileen, Nicod, Jerome, Nightingale, Luke, Nofal, Stephanie, Nurse, Paul, Nutan, Savita, Oedekoven, Caroline, O'Garra, Anne, O'Leary, Jean D, Olsen, Jessica, O'Neill, Olga, Ordonez Suarez, Paula, O'Reilly, Nicola, Osborne, Neil, Pabari, Amar, Pajak, Aleksandra, Papayannopoulos, Venizelos, Patel, Namita, Patel, Yogen, Paun, Oana, Peat, Nigel, Peces-Barba Castano, Laura, Perez Caballero, Ana, Perez-Lloret, Jimena, Perrault, Magali S, Perrin, Abigail, Poh, Roy, Poirier, Enzo Z, Polke, James M, Pollitt, Marc, Prieto-Godino, Lucia, Proust, Alize, Shah Punatar, Rajvee, Puvirajasinghe, Clinda, Queval, Christophe, Ramachandran, Vijaya, Ramaprasad, Abhinay, Ratcliffe, Peter, Reed, Laura, Reis e Sousa, Caetano, Richardson, Kayleigh, Ridewood, Sophie, Roberts, Rowenna, Rodgers, Angela, Romero Clavijo, Pablo, Rosa, Annachiara, Rossi, Alice, Roustan, Chloe, Rowan, Andrew, Sahai, Erik, Sait, Aaron, Sala, Katarzyna, Sanderson, Theo, Santucci, Pierre, Sardar, Fatima, Sateriale, Adam, Saunders, Jill A, Sawyer, Chelsea, Schlott, Anja, Schweighoffer, Edina, Segura-Bayona, Sandra, Shaw, Joe, Shin, Gee Yen, Silva Dos Santos, Mariana, Silvestre, Margaux, Singer, Matthew, Snell, Daniel M, Song, Ok-Ryul, Spyer, Moira J, Steel, Louisa, Strange, Amy, Sullivan, Adrienne E, Swanton, Charles, Tan, Michele SY, Tautz-Davis, Zoe H, Taylor, Effie, Taylor, Gunes, Taylor, Harriet B, Taylor-Beadling, Alison, Teixeira Subtil, Fernanda, Terré Torras, Berta, Toolan-Kerr, Patrick, Torelli, Francesca, Toteva, Tea, Treeck, Moritz, Trojer, Hadija, Tsai, Ming-Han C, Turner, James MA, Turner, Melanie, Ule, Jernej, Ulferts, Rachel, Vanloo, Sharon P, Veeriah, Selvaraju, Venkatesan, Subramanian, Vousden, Karen, Wack, Andreas, Walder, Claire, Walker, Philip A, Wang, Yiran, Ward, Sophia, Wenman, Catharina, Wiliams, Luke, Williams, Matthew J, Wong, Wai Keong, Wright, Joshua, Wu, Mary, Wynne, Lauren, Xiang, Zheng, Yap, Melvyn, Zagalak, Julian A, Zecchin, Davide, Zillwood, Rachel, Matthews, Rebecca, Severn, Abigail, Adam, Sajida, Enfield, Louise, McBride, Angela, Gärtner, Kathleen, Edwards, Sarah, Lorencatto, Fabiana, Michie, Susan, Manley, Ed, Shahmanesh, Maryam, Lukha, Hinal, Prymas, Paulina, McBain, Hazel, Shortman, Robert, Wood, Leigh, Davies, Claudia, Williams, Bethany, Ng, Kevin W, Cornish, Georgina H, Faulkner, Nikhil, Riddell, Andrew, Hobson, Philip, Agua-Doce, Ana, Bartolovic, Kerol, Russell, Emma, Carr, Lotte, Sanchez, Emilie, Frampton, Daniel, Byott, Matthew, Paraskevopoulou, Stavroula M, Crayton, Elise, Meyer, Carly, Vora, Nina, Gkouleli, Triantafylia, Stoltenberg, Andrea, Ranieri, Veronica, Byrne, Tom, Lewer, Dan, Hayward, Andrew, Gilson, Richard, Kelly, Gavin, Roberts, Fiona, Hatipoglu, Emine, and Byrne, Thomas
- Published
- 2020
- Full Text
- View/download PDF
40. Dynamiques contradictoires d’évolution des exploitations agricoles de moyenne montagne corse : spécialiser ou diversifier les exploitations familiales
- Author
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Paoli, Jean-Christophe, Santucci, Pierre, Lafitte, Line-Marie, and Bazin
- Subjects
Montagne ,Vente directe ,Petite exploitation ,Châtaigne ,production agricole ,corse ,économie agricole ,foncier ,méditerranée - Abstract
La montagne corse a fondé son économie agricole contemporaine sur la production de denrées animales et végétales transformées à la ferme et sur l’extensivité du capital investi par rapport au foncier utilisé. Cette double adaptation, qui relève de logiques individuelles plus que d’une action stratégique collective permet aux exploitations de moyenne montagne de dégager des revenus élevés et stables en mobilisant peu de capitaux. Pourtant cette adaptation liée au relatif isolement de la montagne et aux difficultés de mécanisation révèle ses limites : limites environnementales dues au non entretien du paysage associé à une utilisation minière des éléments hérités du système agraire ancien (sols, châtaigneraies, terrasses) d’une part, limites sociales dues aux pertes d’actifs dans un contexte où la coopération est faible, d’autre part. Ces deux limites sont liées au phénomène d’agrandissement des surfaces d’exploitations, incapable de gérer l’espace et le patrimoine dont elles héritent. Elles révèlent le paradoxe d’un patrimoine mis en valeur, notamment au travers des produits vendus, mais guère entretenu.
- Published
- 2016
41. Experimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of Tuberculosis
- Author
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Santucci, Pierre, Bouzid, Feriel, Smichi, Nabil, Poncin, Isabelle, Kremer, Laurent, De Chastellier, Chantal, Drancourt, Michel, Canaan, Stéphane, Enzymologie interfaciale et de physiologie de la lipolyse (EIPL), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), Centre d’études d’Agents Pathogènes et Biotechologies pour la Santé (CPBS), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche en Infectiologie de Montpellier (IRIM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), and Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Adipocyte ,Granuloma ,Macrophages ,Mycobacteria ,Review ,Mycobacterium tuberculosis ,Pathogenesis ,Models, Theoretical ,Lipid Metabolism ,Microbiology ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Host-Pathogen Interactions ,Animals ,Humans ,Amoeba ,Lipid body - Abstract
International audience; Despite a slight decline since 2014, tuberculosis (TB) remains the major deadly infectious disease worldwide with about 1.5 million deaths each year and with about one-third of the population being latently infected with Mycobacterium tuberculosis, the etiologic agent of TB. During primo-infection, the recruitment of immune cells leads to the formation of highly organized granulomas. Among the different cells, one outstanding subpopulation is the foamy macrophage (FM), characterized by the abundance of triacylglycerol-rich lipid bodies (LB). M. tuberculosis can reside in FM, where it acquires, from host LB, the neutral lipids which are subsequently processed and stored by the bacilli in the form of intracytosolic lipid inclusions (ILI). Although host LB can be viewed as a reservoir of nutrients for the pathogen during latency, the molecular mechanisms whereby intraphagosomal mycobacteria interact with LB and assimilate the LB-derived lipids are only beginning to be understood. Past studies have emphasized that these physiological processes are critical to the M. tuberculosis infectious-life cycle, for propagation of the infection, establishment of the dormancy state and reactivation of the disease. In recent years, several animal and cellular models have been developed with the aim of dissecting these complex processes and of determining the nature and contribution of their key players. Herein, we review some of the in vitro and in vivo models which allowed to gain significant insight into lipid accumulation and consumption in M. tuberculosis, two important events that are directly linked to pathogenicity, granuloma formation/maintenance and survival of the tubercle bacillus under non-replicative conditions. We also discuss the advantages and limitations of each model, hoping that this will serve as a guide for future investigations dedicated to persistence and innovative therapeutic approaches against TB.
- Published
- 2016
- Full Text
- View/download PDF
42. Casgi, furmagli e brocci, les fromages corses
- Author
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Sorba, Jean, Casalta, Erick, Santucci, Pierre, Paoli, Jean-Christophe, Laboratoire de Recherches sur le Développement de l'Elevage (LRDE), Institut National de la Recherche Agronomique (INRA), Sciences Pour l'Oenologie (SPO), Université Montpellier 1 (UM1)-Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université Montpellier 1 (UM1)-Université de Montpellier (UM)-Institut National de la Recherche Agronomique (INRA), Unité de recherche Développement de l'Elevage (LRDE), Université Montpellier 1 (UM1)-Institut de Recherche pour le Développement (IRD [Nouvelle-Calédonie])-Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), and Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut de Recherche pour le Développement (IRD [Nouvelle-Calédonie])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)
- Subjects
Fromages ,Corse ,Sociologie ,Economie ,Anthropologie ,production méditerranéenne ,économie ,[SDV]Life Sciences [q-bio] ,fromage - Abstract
absent
- Published
- 2015
43. Deliverable D4.20, Part 2 6 Report on Claim WP4 Task 2, Activity c) (Ad-Hoc studies)
- Author
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Arriaza, M., Bal, Tufan, Borisov, Petar, Cagla, M., Colombo, S., Delattre, Laurence, Ehmeier, Veronika, Galimberti, Giuliano, Giedych, Renata, Gueniot, Florian, Häfner, Kati, Handan Giray, F., Kantelhardt, Jochen, Kapfer, Martin, Kart, Ormeci, Kobus, Pawel, Leonelli, Lara, Majewski, Edward, Maksymiuk, Gabriela, Malak-Rawlikowska, Agata, Manrique, Rosa, MOULERY, Michel, Napoleone, Claude, Nikolov, Dimitre, Paoli, Jean-Christophe, Piorr, Annette, Radev, Teodor, Raggi, Meri, Reindl, Andreas, Rodríguez Entrena, M., Santucci, Pierre, Schaller, Lena, Szulczewska, Barbara, Ungaro, Fabrizio, Targetti, Stefano, van Zanten, Boris, Verburg, Peter, Viaggi, Davide, Wolski, Przemysław, Zasada, Ingo, Zavalloni, Matteo, Instituto Andaluz de Investigación y Formación Agraria y Pesquera (IFAPA), Süleyman Demirel University, Agricultural University [Plovdiv], Universität für Bodenkultur Wien = University of Natural Resources and Life [Vienne, Autriche] (BOKU), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Warsaw Agricultural University, Leibniz-Zentrum für Agrarlandschaftsforschung = Leibniz Centre for Agricultural Landscape Research (ZALF), Unité de recherche d'Écodéveloppement (ECODEVELOPPEMENT), Institut National de la Recherche Agronomique (INRA), Laboratoire de Recherches sur le Développement de l'Elevage (LRDE), VU University Medical Center [Amsterdam], European Project: 289578,EC:FP7:KBBE,FP7-KBBE-2011-5,CLAIM(2012), and Universität für Bodenkultur Wien [Vienne, Autriche] (BOKU)
- Subjects
[SDV]Life Sciences [q-bio] ,[SHS]Humanities and Social Sciences - Abstract
Activity c) represents original studies about the effects of landscape on economic activities and society welfare. These “ad-hoc studies” in Activity c) can be seen as the logical consequence of Activity a) and b): In the ad-hoc study, the knowledge gaps in the process of local answering the project’s guiding questions, that have been detected during Activity a) and b), shall be filled. Furthermore, the ad-hoc studies test innovative methodologies likely to be sufficient in assessing the cause chain effects between landscape and rural development development/regional competitiveness. (At this, testing of methodologies is decided on case by case by the CLAIM consortium, depending on local need (and with a view of providing, altogether a coverage of different potential methods.) Consequently, the different CSA ad-hoc studies do not follow a common methodological approach, as the different local basic conditions and knowledge gaps determine different needs and as a variety of methods shall be tested which could be suitable to address the projects objectives. Part 4 of D4.20 represents the basic report on the application of different methods to a answer the CSA specific research questions and on the final results of the ad-hoc studies. The report is organised country by country.
- Published
- 2014
44. Deliverable D4.20, Part 1 - Summary report on WP4 Task 2, Activities a) b) c) d)
- Author
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Arriaza, Manuel, Bal, Tufan, Borisov, Petar, Cagla, M., Czekaj, Stefania, Delattre, Laurence, Galimberti, Giuliano, Giedych, Renata, Häfner, Kati, Handan Giray, F., Gueniot, Florian, Kantelhardt, Jochen, Kapfer, Martin, Kart, Ormeci, Kobus, Pawel, Leonelli, Lara, Majewski, Edward, Maksymiuk, Gabriela, Malak-Rawlikowska, Agata, Manrique, Rosa, Moulery, Michel, Napoleone, Claude, Nikolov, Dimitre, Paoli, Jean-Christophe, Piorr, Annette, Radev, Teodor, Raggi, Meri, Santucci, Pierre, Schaller, Lena, Szulczewska, Barbara, Targetti, Stefano, Ungaro, Fabrizio, van Zanten, Boris, Verburg, Peter, Viaggi, Davide, Wąs, Adam, Wolski, Przemysław, Zasada, Ingo, and Zavalloni, Matteo
- Published
- 2014
45. Towards a better understanding of local breeds to livestock farming systems: an exploratory methodological proposal
- Author
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Paoli, Jean-Christophe, Viollet, Alice, Santucci, Pierre, Gambotti, Jean-Yves, Lauvie, Anne, Laboratoire de Recherches sur le Développement de l'Elevage (LRDE), and Institut National de la Recherche Agronomique (INRA)
- Subjects
corsica ,breeders points of view ,sheep ,livestock farming systems ,[SDV]Life Sciences [q-bio] ,adaptation ,local breed ,[SHS]Humanities and Social Sciences - Abstract
8. Seminar of the FAO-CIHEAM Sub-Network on Production Systems,Tangier (Morocco) 2013/06/11-13 ISBN : 2-85352-525-2; International audience; Local breeds are often described as adapted to local conditions, but we noticed a lack of characterization of what this adaptation refers to, in particular for breeders themselves. Moreover a single local breed can be involved in a diversity of livestock farming systems types and fodder systems. We proposed a specific research method, aiming to explore adaptation of Corsican sheep local breed to livestock farming systems. We consider that breeders are the first breed managers and as a consequence that the attempt to understand their own point of view on adaptation and their corresponding managing practices is of first importance. We present our method, based on semi structured interviews conducted through a sample of breeders chosen among types of farming systems made up thanks to a preliminary agrarian diagnosis. The analysis of the first results of this survey allows us to discuss this exploratory method proposal
- Published
- 2014
46. Le dilemme de l'élevage sur parcours en Corse : de la politique anti-incendies à la recherche de l'autonomie
- Author
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Paoli, Jean-Christophe, Santucci, Pierre, Laboratoire de Recherches sur le Développement de l'Elevage (LRDE), and Institut National de la Recherche Agronomique (INRA)
- Subjects
élevage pastoral ,aide à la décision ,écologie ,environnement ,politique publique ,pac ,[SDV]Life Sciences [q-bio] ,pastoralisme ,incendie ,ComputingMilieux_MISCELLANEOUS ,[SHS]Humanities and Social Sciences - Abstract
National audience
- Published
- 2014
47. Experimental Evolution of Mycobacterium tuberculosis in Human Macrophages Results in Low-Frequency Mutations Not Associated with Selective Advantage
- Author
-
Guerrini, Valentina, primary, Subbian, Selvakumar, additional, Santucci, Pierre, additional, Canaan, Stéphane, additional, Gennaro, Maria Laura, additional, and Pozzi, Gianni, additional
- Published
- 2016
- Full Text
- View/download PDF
48. Les systèmes d'élevage : quelles évolutions des communications aux 3R depuis 20 ans ?
- Author
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Choisis, Jean Philippe, Cournut, Sylvie, Havet, Alain, Nozieres, Marie-Odile, Santucci, Pierre, Dynamiques Forestières dans l'Espace Rural ( DYNAFOR ), Institut National Polytechnique [Toulouse] ( INP ) -Institut National de la Recherche Agronomique ( INRA ) -Ecole Nationale Supérieure Agronomique de Toulouse, Mutations des activités des espaces et des formes d'organisation dans les territoires ruraux ( METAFORT ), Institut National de la Recherche Agronomique ( INRA ) -AgroParisTech-VetAgro Sup ( VAS ) -Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture ( IRSTEA ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Sciences pour l'Action et le Développement : Activités, Produits, Territoires ( SADAPT ), AgroParisTech-Institut National de la Recherche Agronomique ( INRA ), Elevage des ruminants en régions chaudes ( ERRC ), Centre de Coopération Internationale en Recherche Agronomique pour le Développement ( CIRAD ) -Institut National de la Recherche Agronomique ( INRA ), Unité de recherche Développement de l'Elevage ( LRDE ), Institut National de la Recherche Agronomique ( INRA ), Dynamiques Forestières dans l'Espace Rural (DYNAFOR), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Toulouse-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Mutations des activités des espaces et des formes d'organisation dans les territoires ruraux (METAFORT), Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut National de la Recherche Agronomique (INRA)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-AgroParisTech, Sciences pour l'Action et le Développement : Activités, Produits, Territoires (SADAPT), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Elevage des ruminants en régions chaudes (UMR ERRC), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA), Unité de recherche Développement de l'Elevage (LRDE), Institut National de la Recherche Agronomique (INRA), Institut National de la Recherche Agronomique (INRA)-École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National Polytechnique (Toulouse) (Toulouse INP), Mutations des activités des espaces et des formes d'organisation dans les territoires ruraux (UMR METAFORT), AgroParisTech-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Recherche Agronomique (INRA)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), AgroParisTech-Institut National de la Recherche Agronomique (INRA), Laboratoire de Recherches sur le Développement de l'Elevage (LRDE), Institut National de la Recherche Agronomique (INRA)-École nationale supérieure agronomique de Toulouse (ENSAT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT), and Institut National de la Recherche Agronomique (INRA)-AgroParisTech-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)
- Subjects
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences ,Systèmes d'élevage ,rétrospective ,[ SDV.SA ] Life Sciences [q-bio]/Agricultural sciences - Abstract
absent
- Published
- 2013
49. Relation between farming systems, the CAP subsidies and the fires that occur in the forested mediterranean areas. A Corsican case study
- Author
-
Delattre, Laurence, Paoli, Jean-Christophe, Santucci, Pierre, Gueniot, Florian, Napoleone, Claude, MOULERY, Michel, Leonelli, Lara, Unité de recherche d'Écodéveloppement (ECODEVELOPPEMENT), Institut National de la Recherche Agronomique (INRA), Laboratoire de Recherches sur le Développement de l'Elevage (LRDE), and Searchlight.
- Subjects
[SDV]Life Sciences [q-bio] ,ComputingMilieux_MISCELLANEOUS ,[SHS]Humanities and Social Sciences - Abstract
International audience
- Published
- 2013
50. Towards a better understanding of adaptation of local breeds to livestock farming systems: an exploratory methodological proposal
- Author
-
Paoli, Jean-Christophe, Viollet, Alice, Santucci, Pierre, Gambotti, Jean-Yves, Lauvie, Anne, Laboratoire de Recherches sur le Développement de l'Elevage (LRDE), Institut National de la Recherche Agronomique (INRA), and Centre International de Hautes Etudes Agronomiques Méditerranéennes (CIHEAM). FRA.
- Subjects
[SDV]Life Sciences [q-bio] ,ComputingMilieux_MISCELLANEOUS ,[SHS]Humanities and Social Sciences - Abstract
International audience
- Published
- 2013
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