1. Synthetic methodologies to access bioactive bis-coumarin scaffold: a recent progress.
- Author
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Bedi, Pooja, Chaudhary, Diksha, Bose, Reshmi, Santra, Soumava, Ansari, Kashif R., Kaur, Rajbir, Pramanik, Tanay, Sangtam, Therola, and Singh, Ambrish
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COUMARINS ,ORGANIC synthesis ,SYNTHETIC biology ,PHARMACEUTICAL chemistry ,CHEMICAL biology ,ANTINEOPLASTIC agents ,RESEARCH personnel - Abstract
Heterocyclics particularly those containing oxygen and nitrogen atoms are unique precursors for the synthesis of various agrochemicals and pharmaceuticals. Bis-coumarins are well-known oxygen-containing heterocycles of great significance. The development of methods to prepare bis-coumarins is of great interest in synthetic organic chemistry because of their versatile importance in medicinal chemistry and chemical biology. Bis-coumarins are well known for their antibiotic, antimicrobial, anti-HIV, and antitumor activity. Due to the vast application of bis-coumarins, the synthesis of these heterocycles has attracted huge interest from researchers. In this review, we have summarized the diverse synthetic routes of bis-coumarin synthesis making use of different catalysts and solvents under versatile reaction conditions. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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