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This experience report describes the procedures used by Dentistry in its dialogue with parents and guardians of children and adolescents with developmental disabilities and with the interdisciplinary team of the Integrated Rehabilitation Service of the Minas Gerais Rehabilitation Association, to establish a unique therapeutic project to achieve the general health and social integration of its patients. To this end, a documentary analysis was carried out of the articles published in full by this project that describe this dialogue. The discussion was guided by ethno methodology, considering the subjects involved in the debate, their socio-economic and cultural contexts, and the limits of care offered by the Unified Health System (SUS). [ABSTRACT FROM AUTHOR]

Copyright of GeSec: Revista de Gestao e Secretariado is the property of Sindicato das Secretarias e Secretarios do Estado de Sao Paulo (SINSESP) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Curcumin, found in turmeric rhizomes (Curcuma longa L.), has been widely studied for its potential health benefits, including anti-inflammatory, antioxidant, and wound-healing properties. However, due to its low bioavailability and unfavorable pharmacokinetics, analogous compounds have been developed to obtain better biopharmaceutical characteristics and enhanced biological effects. In this study, we evaluated the activity of curcumin and three of its synthetic analogues (DMAD, DMAM, and RI75) on the viability and differentiation of a pre-osteoblastic cell line (MC3T3-E1). We also assessed the expression of key genes involved in tissue regeneration: vascular endothelial growth factor (vegf), stromal-derived growth factor 1 (SDF-1/CXCL12), and runt-related transcription factor 2 (runx2). The cells were treated with curcumin and the three analogues at concentrations of 10, 30, or 50 µM. All tested analogues and curcumin exhibited moderate to no cell toxicity compared to the cells treated under standard conditions across all concentrations after 24, 48, and 72 hours. Only the RI75 analogue showed upregulation of SDF-1, a crucial factor in tissue regeneration. Compared to curcumin, the DMAM and RI75 analogues also upregulated runx2 and vegf, both associated with osteodifferentiation. The RI75 analogue demonstrated greater mineralization than curcumin, and both promoted more nodule formation than the untreated control. Our data suggest that the curcumin analogue RI75 at 50 µM presents similar toxicity but enhanced biological activity compared to natural curcumin, making it a promising substance for material biomodifications. [ABSTRACT FROM AUTHOR]

Purpose: The objective of this study was to evaluate the roughness characteristics, micrograph and hardness of a conventional dental composite resin subjected to two different forms of sterilization. Methods: Were made 30 cylindrical proof bodies (10.0 x 2.0 mm) of composite resin divided into 3 groups. Group A: the samples were sterilized by autoclaving; Group EO: the samples were sterilized by ethylene oxide; and Group C (control): the samples were not subjected to the sterilization process. The surface roughness was evaluated using the Surface Roughness Tester device (Time Group Inc. - TR200®, São Paulo, Brazil) apparatus in all bodies in each group. The micrograph was performed by microscopic photographic test conducted in only one sample of each group with an inverted optical microscope (Kontrol - IM-713®, USA). The Vickers microhardness was assessed through penetration intervention on 50 grams of force per 10 seconds for all bodies of the test piece. Results: The groups did not show statistically significant differences in roughness. Regarding microhardness, the group sterilized by autoclave presented inferior results to the other groups. In the micrographic evaluation, it was observed that the test groups presented greater irregularity in relation to the control group. Clinical relevance: Resin composite is the most widely used dental restorative material in practice today and the sterilization is very important to prevent contamination and ensure the specific action of the inoculated microorganisms, in the researches with the material. However, the literature is quite sparse regarding polymer sterilization although its use is cited in several areas. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this article is to describe a new technique for casting dies and mounting dental cast on simple hinge articulators using Lego blocks. The objective of this study is achieve a simple and low cost technique for optimizing the dentist's time and cost when using simple hinge articulators. Methods: Lego Blocks measuring 50mmx30mmx5mm were placed in the hinge articulator with cyanoacrylate adhesive, and solid vaseline was applied on the blocks. The models were then fixed to the blocks with Type III plaster and dies were cast. Results: This technique guaranteed good precision and retention, optimizing the dentist's time and cost, in addition to allowing the professional to use one and the same hinge articulator for different dental casts simultaneously. Clinical relevance: The hinged articulator may be indicated to help with the fabrication of single unit prostheses and for fast procedures. Considering the need to facilitate the day-to-day clinical work of dentists in terms of cost, simplicity and time, a technique capable of allowing work on several working models simultaneously will facilitate the work and optimize clinical practice, maintaining the accuracy. [ABSTRACT FROM AUTHOR]

Purpose: The aim of the study was to evaluate the load fixed partial dental prostheses (FPD) fracture of four elements made with two types of infrastructure material: Y-TZP (polycrystalline tetragonal zirconia-based ceramic stabilized by yttria) and NiCr alloy (control). One pre-molar and one molar were prepared with 3° inclination on opposing surfaces and 2 mm of occlusal surface reduction in a master model. Next, 24 models were fabricated in F23 polyurethane. All models were obtained from duplication of preparations. Ten FDPs with NiCr alloy infrastructures (control group) and 10 with Y-TZP infrastructures (experimental group) were cemented on the models. A fracture strength test of the dentures was performed by means of axial compression in a Universal Test Machine EMIC DL2000, with a 2000 Kgf load cell and speed of 1.0 mm/min. The data were submitted to Student's-t test for independent samples (α = 0.05). Results: NiCr group showed higher maximum fracture strength force (1968.78N) than did the Y-TZP group (1020.12N) (p<0.001). It can be concluded that the FPDs four elements metal-ceramic provide better fracture strength that metal-free FPDs. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to perform a review of the literature regarding the survival rate of dental implants with immediate loading using insertion torque of 30 Ncm. Material and Methods: A systematic review was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and the Cochrane Handbook for Systematic Reviews of Interventions (PROSPERO CRD42014015323). The search was performed in the PubMed, Web of Science, Cochrane Library electronic, OVID, and Scielo databases. Manual searches were also performed. The articles identified were assessed independently by 3 researchers. Clinical trials reporting dental implants with immediate loading and 30 Ncm torque in patients ages 18 years or older were included. Results: The searches yielded 589 studies. Six studies were included in the systematic review. The survival rate of dental implants was 96.8%. Three studies showed a low potential risk of bias. Conclusion: There is not strong evidence that insertion torque of 30 Ncm is enough for implant survival in cases of immediate loading. [ABSTRACT FROM AUTHOR]

Copyright of Implant Dentistry is the property of Lippincott Williams & Wilkins and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)